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Category Archives: Transhuman News

The Chinese Government Has Convinced Its Citizens That the U.S. Army Brought Coronavirus to Wuhan – VICE

Posted: April 9, 2020 at 6:25 pm

U.S. Army sergeant Maatje Benassi was among several hundred U.S. service men and women who traveled to Wuhan to take part in the Military World Games in October.

But, according to a widely-believed conspiracy theory, the 52-year-old road racing cyclist carried something else with her on her trip to China: The coronavirus.

The story has no grounding in fact. It was a fairy tale dreamed up by U.S. conspiracy theorist George Webb in Washington, DC. But the Communist Party of China (CCP) has promoted it so aggressively within China that it has become accepted knowledge among the Chinese populace that the U.S. military imported the coronavirus to Wuhan and began the pandemic that has killed over 50,000 people and infected more than a million worldwide.

Its difficult to say how many Chinese people accept the conspiracy as true, but the CCPs promotion of the idea across social networks WeChat and Weibo, as well as amplification through state-run TV, has made it inescapable in Chinese society. Indeed, any Chinese person who disputes that narrative on social media can have their account shut down and their families arrested.

I couldn't argue against the posts that the virus was brought to China by the U.S. military even though I knew it was a lie because any evidence I post against the Chinese government propaganda will be deleted, the Wechat group can be deleted, my account will be suspended and I can put my family in danger, one Chinese American named Zhang, who did not want to be named over fears of retribution, told VICE News.

READ: China is now blaming a lone US cyclist for the coronavirus pandemic

Globally, Beijings efforts to deflect criticism and pin the blame on the U.S. have been hit and miss, but at home, the effort has been hugely successful. More than half a dozen China experts say there is widespread acceptance of the narrative which has found a receptive audience thanks to decades of anti-US indoctrination and a complete lack of an independent media or access to outside sources.

Sadly most Chinese people really believe the U.S. brought the virus to China and they call it USA virus, Lucy, a 45-year-old Chinese American who recently returned to China to take care of her parents, told VICE News. The CCPs anti-American propaganda is very successful.

Conspiracy theories around the origin of the coronavirus are not unique to China. We have seen everyone from celebrities sharing a video claiming Bill Gates created the coronavirus to Sen. Tom Cotton claiming the disease was deliberately created in a virology lab in Wuhan.

But what is unique to China is the inability for most citizens in the country to fact-check the claims being made by official CCP outlets, or to seek any independent information outside Chinas Great Firewall, which blocks access to most western news outlets and other sources of information, such as Google and Wikipedia.

READ: Here's how China is rewriting the history of the coronavirus pandemic to make itself the hero

Chinese citizens are fully aware that their government censors criticism of Beijing on WeChat and Weibo while pushing messages that portray it in a positive light. Theyre also aware of the consequences for challenging that or for seeking outside information.

When the government spreads disinformation about other countries and blocks counter-narratives, it is much easier for people to buy into governments narratives because you just dont have access to alternative sources of information, Yaqui Wang, a China researcher at Human Rights Watch, told VICE News.

And when it comes to claims about the U.S. Chinese people have been conditioned to believe the worst.

CCP disinformation about the U.S. is nothing new, through textbooks, movies and many other educational, cultural, and media productions, Beijing has been increasingly promoting the narrative that the U.S. is an imperialist power that wants to undermine the rise of China.

Chinese media doesnt need much effort to convince its people of that blatant lie that the U.S. army brought the disease to Wuhan, most Chinese people, after 70 years of anti-American propaganda, are already convinced the U.S. is an evil country and is responsible for many bad events in the world, Lucy said.

Inside of China the conspiracy spread rapidly through WeChat, a messaging app that is so deeply integrated into Chinese life that losing your account means losing access to banking, online shopping, ordering taxis and much more.

According to Zhang, the conspiracy theory was shared in multiple WeChat groups they were in, and in such a way that it looked like a coordinated effort.

A few weeks ago, I started to see posts about the virus was brought to China by the U.S. military, the source said. All the posts appeared in different WeChat groups at around the same time. Keep in mind most WeChat groups are completely independent of each other. For the same posts to show up in all the large WeChat groups at the same time, it has to have the government behind it.

The CCP has a huge amount of control over how WeChat operates and has already shown its willingness to use that power to control the coronavirus narrative.

It has banned WeChat users inside the country who have shared anything vaguely negative about the governments response to coronavirus, it has silenced overseas WeChat users without their knowledge, and it has ramped up the level of censorship on the topic of coronavirus as the epidemic escalated.

READ: Wuhan's crematoriums are filling thousands of urns with coronavirus remains each day

The fact China has not banned this topic from being discussed on WeChat shows that it is happy for it to continue to be disseminated.

The topic has been widely discussed on WeChat and Weibo, one Hong Kong-based social media researcher known by the Twitter handle Chelsea, told VICE News. The CCP doesnt censor the discussion of origin. As most Chinese think the virus is not from China. I think this is the direction that CCP want it to keep going.

The view is backed up by Victor Shih, a China expert at the University of California.

Although the Chinese government and Chinese tech companies have demonstrated numerous times that they have the capacity to stop rumors and forwards from going viral on WeChat using censorship tools, they have not chosen to stop this groundless theory from circulating among Chinese communities, Shih told VICE News.

But unlike previous anti-U.S. propaganda, this time around Beijing is also seeking to sow disinformation further afield. What is new this time is that China is doing this kind of disinformation externally, on Twitter, a platform blocked in China, and through its external-facing media outlets, Wang said.

Research published this week by the Stanford Internet Observatory shows that the seeds of the conspiracy go back at least to January, when news of the virus in Wuhan.

It is unclear when the conspiracy theory was first floated or by whom, but it had gained enough traction by the turn of the year that on Jan. 2, a Chinese-language YouTube channel shared a video dismissing the idea that the pneumonia in Wuhan was the result of U.S. genetic warfare.

READ: China is trying to rewrite the history of silenced coronavirus whistleblower doctor Li Wenliang

It was around this time that whistleblower doctor Li Wenliang tried to warn friends about a growing pneumonia-like virus spreading in his hospital in Wuhan before the government silenced him.

The researcher said that because platforms have pledged to remove disinformation related to the origin of the coronavirus, and our research started in mid-March, some materials could have been removed.

Throughout January and February, the conspiracy theory continued to filter through on platforms like YouTube and Twitter which are banned in China and the English-language versions of Chinas state-backed media also began boosting the unfounded claims.

Then, in March, Foreign Ministry spokesperson Zhao Lijian gave the conspiracy the CCPs seal of approval, tweeting that It might be U.S. army who brought the epidemic to Wuhan.

A week later he doubled down on the claim, citing Webbs conspiracy theory about Benassi being coronavirus patient zero, without a shred of evidence.

Beijings reason for persisting with these claims is simple.

While people are discussing and debunking these conspiracy theories, they are not talking about its initial failings in responding to the outbreak and the questions being raised over the veracity of the figures it has shared about the outbreak.

Propaganda like this largely serves the leadership's interests in that it takes attention away from other problems in China, one of the co-founders of GreatFire.org, an organization that tracks Chinas online censorship, told VICE News, using the pseudonym Charlie Smith. You and many of your peers are covering this story now instead of covering other, more truthful, and likely hurtful, stories. It's a waste of everyone's time except The Party's.

Cover: A couple wearing face masks arrive at the railway station in Wuhan, in China's central Hubei province on April 6, 2020. (Photo: HECTOR RETAMAL/AFP via Getty Images)

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William Wordsworth was the supreme bard of nature and solitude – The Economist

Posted: at 5:58 pm

Two hundred and fifty years after his birth, he remains a poet of blessed consolations in distress

IN THIS SEASON of cancelled parties, the 250th anniversary of William Wordsworths birth will also go unmarked in public. Celebrations of the English poet, born on April 7th 1770, should have bloomed like his beloved daffodils all over the Lakeland region (pictured), and beyond. He taught not only his compatriots but devotees around the world to be, like him, a lover of the meadows and the woods, / And mountains; and of all that we behold / From this green earth. Now the British landscapes he trudged through are empty of the visitors that his verse attracted from overcrowded Victorian cities. (Indeed, in his later years Wordsworth fretted about the mass tourism that his Romantic worship of unspoilt nature had fostered. Is then no nook of English ground secure / From rash assault? he thundered when the Kendal and Windermere railway, designed to carry Wordsworthian excursionists, was proposed in 1844.)

Wordsworth has lately stridden back into fashion as a pioneer ecologist, a green visionary. For him, nature is a single, interconnected system. Every child joins it not as an alien manipulator but, as his autobiographical epic, The Prelude, puts it, an inmate of this active universe; even as an agent of the one great mind. The fledgling poet, his mature self recalled, grasped and gloried in the interdependence of nature, for in all things / I saw one life, and felt that it was joy. The so-called Gaia hypothesis of modern environmentalism starts here.

First-hand encounters with the healing benefits of fell and vale have now been put on hold. Still, the bard of the great outdoors has lessons for people trapped inside by natural forces greater than human will. In a period of enforced apartness, Wordsworths lifelong pursuit of joyous solitude seems timelier than ever. He contrasted calm, reflective isolation with the loneliness of compulsory sociability. As his poem Home at Grasmere warns, he truly is alone, / He of the multitude whose eyes are doomed / To hold vacant commerce day by day / With that which he can neither know nor love.

For Wordsworth, solitude brings joy above all because it carves out space for memory. Even his over-familiar daffodils (I wandered lonely as a cloud) matter most not at first sight but when, recollected, they flash upon the inward eye / Which is the bliss of solitude. More than the treks, tours and climbs around picturesque locations that filled his years and drew generations of disciples to ramble after him, what Wordsworth cherished was memory as solace and strength. The Prelude finds meaning not so much in the rapture of observation as the balm of reminiscence, since The earth / And common face of Nature spake to me / Rememberable things. Uncannily, his great poem of 1798, Lines written a few miles above Tintern Abbey, talks of finding relief through memory from the fever of the world. That relief comes in fond thoughts of the winding river Wye, Thou wanderer through the woods, / How often has my spirit turned to thee.

Generations of readers have noted that Wordsworths own memory-enriched solitude was companionably shared: his poetic jaunts around the Lakes depended on the decades-long support provided by his sister Dorothy, wife Mary, and sister-in-law Sara. This champion of rugged hermits, outcasts and nomads could always walk home to warm fires and friendly faces. He did, however, live with grief and lossof his parents, his brother, of two young children, and of the political hopes prompted by the French Revolution that later shattered into what he calls these times of fear / This melancholy waste of hopes oerthrown.

As a poet of comfort via simple, everyday experience, of blessed consolations in distress, he remains without equal. The philosopher John Stuart Mill paid the finest tribute to this gift. Stricken by a depressive breakdown after his hyper-intellectual youth, Millas his Autobiography of 1873 explainsfound in Wordsworth a supremely effective medicine for my mind. His poems fed Mill with a source of inward joy, of sympathetic and imaginative pleasure, which could be shared in by all human beings. As Mill put it: I felt myself at once better and happier as I came under their influence.

During this spell of collective standstill, that power need not dimand you do not need to contemplate some awesome summit, torrent or ravine to feel it. As the Ode: Intimations of Immortality confesses, To me the meanest flower that blows can give / Thoughts that do often lie too deep for tears. Look closely when out on your next state-approved stroll.

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Preventing Coronavirus Exposure When You Have Psoriasis and Eczema – Everyday Health

Posted: at 5:53 pm

Living with psoriasis and atopic dermatitis, or eczema, means Im always thinking twice about what might exacerbate these skin conditions. I need to especially consider what in my environment might trigger itchiness or rashes. Now, as were all faced with the novel coronavirus, Im even more vigilant about how practices such as frequent hand-washing and disinfecting may affect my health.

Take, for example, a recent shopping trip to my local Costco. I grabbed a shopping cart before entering, much like any other time. On this visit, though, a bleach wipe container sat on a table inside the door. I dutifully took a wipe to disinfect the cart handle. Then I looked at my hands, wondering if I should wipe them too and thinking about how it might irritate my skin.

The Centers for Disease Control and Preventions (CDC) website lists ways to protect yourself from exposure to the coronavirus. Im already at a higher risk for serious illness because I have asthma. Im also concerned that I might be at a higher risk because I take a biologic to treat psoriasis.

RELATED: What You Need to Know About the New Coronavirus if You Have Asthma

The National Psoriasis Foundation Medical Boards recommendations for those with psoriatic disease state that patients with severe disease, those on potentially immunosuppressive therapies and those presenting with comorbid conditions may be at a higher risk for infection. They recommend patients contact their healthcare providers office with any concerns related to treatments such as biologics.

Even if you are not in a higher risk group for COVID-19, the public health message is for everyone to follow measures to stop the spread of the coronavirus.

A repeated message to stop the spread is to clean hands frequently, ideally with soap for at least 20 seconds. If soap is not available, then hand sanitizer with at least 60 percent alcohol serves as a replacement. Unfortunately, frequently cleaning my hands dries them out. Soaps and hand sanitizers can contain perfumes that my skin reacts to as well.

The American Academy of Dermatology Association (AAD) recommends that you leave some water on your hands when drying them and apply hand cream or ointment while theyre still damp. The AAD also points out that dermatologists recommend using a cream or ointment that contains mineral oil or petrolatum and says its fragrance-free and dye-free.

Another CDC guideline is to avoid touching your eyes, nose, and mouth, because they can serve as pathways for the virus to enter the lungs and throat. Germs can spread when you touch a contaminated surface, such as a doorknob or countertop, and then touch your face.

Touching the face is something people often do without even noticing. A study published in February 2015 in the Journal of Infection Control observed that students touched their faces 23 times an hour, with 44 percent of touches involving a mucous membrane. With rashes on my face, including my eyelids, it can be very difficult for me not to touch my face.

On their website, the National Eczema Association responded to questions related to the coronavirus, including how to avoid touching facial eczema. Their first recommendation is to practice distraction techniques such as playing handheld video games, arts and crafts, or playing a musical instrument.

They also recommend using competing responses, which replace one behavior with another. For example, every time I want to touch my face, I might snap my fingers or touch my leg instead. They conclude, If you do need to deliberately touch your face, wash your hands first; avoid the nose, eyes and mouth; and perhaps use a clean cloth or Kleenex.

Since psoriasis and eczema on my face is an ongoing issue, I follow my facial skin treatments carefully to reduce irritation and itchiness. Contact your healthcare provider or dermatologist if you need to address skin concerns on your face.

Keeping social distance to prevent the coronavirus is critical, but it can be very isolating especially for people living with a chronic condition.

Fortunately, we live in an age where people connect through a variety of electronic means, such as video and text chat, virtual communities, or online games and activities. I felt uplifted and encouraged after recently joining a church group on a video chat. If you are sheltering at home, you may have more time to catch up with old friends and family.

Virtual connections can even help you communicate with your doctor. TheNPF Medical Board, for example, recommends telehealth appointments whenever possible for routine visits during the pandemic. Both my daughters successfully used telehealth for their recent doctor appointments. I utilized messaging to discuss my psoriasis with my dermatologist.

RELATED: Your Everyday Guide to Telemedicine

Living with skin diseases might add some complication to following CDC guidelines, but they can be overcome. Lets pledge to do so together to flatten the curve and save lives.

Here are some resources to help answer your questions about managing psoriasis and eczema these days:

National Eczema Association (NEA): Ask the Ecz-perts: Coronavirus (COVID-19)

National Psoriasis Foundation (NPF): Coronavirus Concerns?

NPF Psound Bytes podcast: Ep. 64 "Coronavirus and Psoriatic Disease: Your Questions Answered"

You can read more about my experiences in myblogfor Everyday Health and on mywebsite.

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Natural Moisturizers That Will Soothe Dry Skin From All Your Hand Washing – HuffPost Canada

Posted: at 5:53 pm

Were all washing our hands multiple times a day to help keep us safe from COVID-19, but the non-stop scrubbing leaves our hands a lot drier than were used to.

Frequent washing draws moisture from the skin, and for those of us that are prone to dry skin, eczema, or have other sensitivities, something to soothe our hands post-wash is a necessity (not to mention a relief).

WATCH: Songs thatll help you remember how long to wash your hands. Story continues below.

Weve rounded up a selection of some of our favourite natural hand creams to nourish and soften our skin, all of which can be safely delivered in Canada.

Clinically tested and proven to protect against excessive dryness and eczema, we keep a tube of Skinfix Hand Repair Cream at the ready for repeated hand washings, and pop it into our pockets for post-sanitizing moisture when were out for a socially distanced walk.

A combination of healing botanicals and natural oils including colloidal oatmeal and sweet almond oil relieves our hands of itching and irritation while providing the nourishment we need.

A luxurious treat for tired and dry hands, the uplifting floral fragrance of this cream helps us unwind, while argan oil, shea butter, and aloe vera nourishes our skin with vitamins and fatty acids.

VladimirFLoyd via Getty Images

We also appreciate that Kahina donates a portion of their annual revenue to support the communities of the Moroccan workers who harvest the argan oil.

This gluten-free and vegan lotion is perfect for hands (or anywhere else on the body!) and most of the ingredients are sourced from local Canadian growers.

We keep our bottle next to the sink for a simple pump or two after washing our hands, and we love the fresh scent of rosemary, citrus, and lavender. The notes of lavender in particular help calm us after a tough day studies have shown that lavender can help reduce stress and anxiety.

Weve found a relaxing self-hand massage before bed is a soothing way to wind down, and this lotion is a lovely addition to our mindful ritual.

The cream nourishes our skin like a dream thanks to organic argan oil, olive oil, and an aromatic blend of essential oils.

A blend of sustainably sourced shea butter, palm and coconut oil gathered through womens collectives in Ghana repairs and soothes dry, sensitive skin.

We love using this cream on our hands as its enriched with vitamin E, which has anti-aging properties and can help reduce inflammation.

WATCH: Six tips to keep your hands moisturized from all that washing. Story continues below.

Unscented and perfect for tucking into a pocket or keeping on the nightstand, this made-in-Toronto blend of camellia, hemp and meadowfoam oil protects our hands night and day.

The fresh scent and smooth feel of this easily absorbed hydrating hand cream almost makes up for the fact that were washing our hands a dozen times a day.

Made of a dermatologically tested and certified natural blend of sea buckthorn (traditionally used to repair and renew skin), sesame, and essential oils, this cream works wonders on our chapped hands.

We got a giggle from Cocoon Apothecarys cute product name (a bit ironic since were missing hugs and physical contact right now), and the Touchy Feely Lotion itself is one of our faves to protect our skin from dryness and the effects of ongoing hand washing.

The spring-fresh scent of lavender and rosemary boosts our mood, while organic olive oil helps our hands stay soft.

This soothing hand lotion, made from a healing blend of lavender, aloe and grapeseed, instantly moisturizes our skin and uplifts our spirits with a soothing scent.

Available in either a convenient pump dispenser or a portable tube, the upside to all this hand washing (asides from the health benefits) could be the opportunity to heal our skin with this aromatic and therapeutic lotion.

For extra sensitive skin, or for those of us who are feeling the effects of multiple lathers, this cream is a gentle, fragrance-free option to protect our hands.

Hypoallergenic and dermatologist tested, this oatmeal-based cream instantly soothes and helps to gently moisturize and soften.

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Here’s Why Regenerons Stock Is Worth More Than Its Coronavirus Work – Motley Fool

Posted: at 5:53 pm

Regeneron's (NASDAQ:REGN)stock has increased by 34% in 2020 as the company and its partner Sanofi (NASDAQ:SNY) initiated two large scale phase 2/3 clinical trials in March where it is providing an existing drug, Kevzara, to treat patients with severe COVID-19, the disease caused by the novel coronavirus. This development has investors optimistic about its prospects. But Regeneron's financial performance for the full year will be driven by the company's core business of treating eye diseases, asthma, eczema, and cancer.

Let's take a closer look at the biotech stock's main revenue drivers to decide if it's a buy today.

Image Source: Getty Images

As of April 9, there have been over 1.4 million worldwide confirmed COVID-19 cases and almost 90,000 virus-related deaths. While there are no approved drugs to effectively treat COVID-19 patients, many companies, including Regeneron, have commenced clinical trials to determine whether existing compounds used for other diseases can help these patients recover.

In March, Regeneron and Sanofi announced that they initiated two large phase 2/3 trials to assess whether Kevzara can prevent lung damage and respiratory distress in patients with severe COVID-19. Regeneron and Sanofi currently market Kevzara as a treatment for adult patients with rheumatoid arthritis (RA).Kevzara blocks the interleukin-6 (IL-6) protein, which may cause a patient's immune system to overreact and damage the lungs.

Recently, a preliminary study performed at a Munich Hospital found patients who have a minimal amount of IL-6 protein have significantly lower rates of respiratory failure and may not need mechanical ventilation. Earlier, a small Chinese study showed that patients who received Actemra, Roche Holdings' (OTC:RHHBY) IL-6 receptor antagonist and competing RA drug, were able to be discharged from the hospital and return home.

Eylea, an injectable drug that prevents blindness, grew by 14% in the U.S. to over $4.6 billion in 2019 (about 60% of Regeneron's sales).Eylea's revenues should continue to increase as it the company fully launches a pre-filled syringe delivery option for physicians and continues to market to the drug to adults with age-related macular degeneration (AMD), a disease that affects almost 11 million people in the U.S and is the leading cause of vision loss in Americans 60 and older. Eylea prevents the disease from progressing to an advanced stage and results in rapid, large sustained improvement for patients with mild to moderate AMD.

Regeneron will also benefit from growth in its diabetic eye business as it has established a dedicated salesforce to specifically contact specialists that see these types of patients. The company is devoting a significant amount of resources to improve on the low current rates of diagnosis and treatment of diabetic retinopathy (DR). DR is a complication of diabetes that causes damage to the retina and can lead to severe vision loss. Early treatment with Eylea, however, can halt the progress of DR, reducing the risk of blindness. This is a welcome development for the almost 8 million people who have DR.

Dupixent sales reported by Sanofi grew by almost 151% to over $2.3 billion in 2019 as physicians prescribed the drug to other adult patients with eczema and treated patients in three new sub-segments (asthma, children with eczema, and adults with chronic long-term sinus inflammation linked to nasal polyps). While Sanofi records all of global Dupixent sales on its income statement, it paid Regeneron over $1.4 billion in contribution revenue in 2019, up 40%, relating to royalties and profits from Dupixent (and two other drugs).

Dupixent should continue to grow as it is used for other patients in these three markets and it will enjoy further growth if it obtains approval from the Food and Drug Administration (FDA) for using the drug for asthma in pediatrics, chronic obstructive pulmonary disease, eczema in pediatrics, and several other indications.

Regeneron generated $176 million in revenue from Libatyo in 2019, up from almost $15 million in 2018. Libtayo treats advanced Cutaneous Squamous Cell Carcinoma (CSCC), a form of skin cancer that accounts for an estimated 7,000 deaths each year in the U.S. As of November 2019, its share of U.S. patients with CSCC was 43%, up from 3% when it was launched in October 2018.

Regeneron is currently testing Libtayo in Non-Small Cell Lung Cancer (NSCLC) patients, cervical cancer, and Basal Cell Carcinoma (BCC; the most common form of skin cancer). Libtayo's revenues should increase in the near-term as physicians continue to prescribe the drug for their CSCC patients and the drug is eventually used in other types of cancers.

I consider to be Regeneron a buy right now because it has ample opportunity to increase the revenue and profits it currently generates from its three key drugs, Eylea, Dupixent, and Libtayo. While investors will be waiting for further updates on Kevzara, they should focus and monitor Regeneron's progress in expanding its the diabetic eye segment, further penetrating the three emerging areas for Dupixent, gaining market share in CSCC, and obtaining FDA approval for treating other indications with these drugs.

While it's easy to be enthralled by its progress in the COVID-19 space, investors thinking about buying Regeneron would do well to consider the stock from a more holistic stance. And it looks good from here.

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1 protein in the skin kickstarts a pesky itch – Futurity: Research News

Posted: at 5:53 pm

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A commonly expressed protein called periostin can directly activate itch-associated neurons in the skin, according to new research.

The researchers found that blocking periostin receptors on these neurons reduced the itch response in a mouse model of atopic dermatitis, or eczema. The findings could have implications for treatment of this condition.

Itch sensations are transmitted from neuronal projections in the skin through the dorsal root ganglia (DRG)clusters of sensory cells located at the root of the spinal nervesthen to the spinal cord.

We have found that periostin, a protein that is produced abundantly in skin as part of an allergic response, can interact directly with sensory neurons in the skin, effectively turning on the itch response, says lead author Santosh Mishra, assistant professor of neuroscience at North Carolina State University. Additionally, we identified the neuronal receptor that is the initial connection between periostin and itch response.

The researchers identified a receptor protein called v3, expressed on sensory neurons in skin, as the periostin receptor.

In a chemically-induced mouse model of atopic dermatitis, the team found that exposure to common allergens such as dust mites increased periostin production in skin, exacerbating the itch response. However, when the researchers turned off the receptor protein, itch reduced significantly.

Periostin and its receptor connect the skin directly to the central nervous system, Mishra says. We have identified the first junction in the itch pathway associated with eczema. If we can break that connection, we can relieve the itch.

The research appears in Cell Reports.

Funding for the work came from NC States startup fund. Additional researchers from NC State, Wake Forest University, and Duke University contributed to the work.

Source: NC State

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The 9 Best Bath Salts and Soaks of 2020 Reviews – Allure

Posted: at 5:52 pm

During these dare I say it again strange and uncertain times, it's so important to find ways to unwind and stay calm amid all of the craziness. Lately, one of our personal favorite activities for self-care has been taking baths, not only because we have more time on our hands, but because it's a soothing experience for both the body and mind.

Add some bath salts or a muscle-relaxing soak into the mix and it gets even better. (Spa-like, some might say.) There's a variety of options to choose from, too... bath bombs, dead sea-infused salts, and colloidal oatmeal elixirs, just to name a few.

As always, Allure editors were more than happy to share some of their most-loved products, but we also tapped two board-certified dermatologists for their go-to bath picks. Take it from us: These skin-loving salts and soaks turn bathtime into a serious treat.

Now enough chit-chat ahead, find nine amazing options that are worth adding to your arsenal if you want to soak the stress away, and get softer skin while you're at it.

All products featured on Allure are independently selected by our editors. However, when you buy something through our retail links, we may earn an affiliate commission.

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Covid-19: Frequent hand-washing, sanitising giving rise to skin problems – New Straits Times Online

Posted: at 5:52 pm

SINGAPORE: In the last few months, senior patient service associate Judy Tan, 56, who works at Singapores National Skin Centre, has been struggling to find a balance between managing her eczema-prone skin and maintaining tip-top hand hygiene at work.

Tan suffers from irritant hand eczema on her right hand, a skin disease commonly seen in people working in the healthcare and food industry due to stringent hand hygiene practices.

Her work at the National Skin Centre involves handling patient enquiries, clinic registration as well as appointments and billing matters.

The eczema on her hands, which started about two years ago, has left her with painful, dry and cracked skin. Sometimes, the cracked skin would bleed.

Even the simple act of washing the dishes or shampooing her hair is challenging when her skin acts up.

The ongoing Covid-19 pandemic has made it even more challenging for her as healthcare workers must sanitise their hands after each patient encounter.

Tan, who works in a subsidised dermatology clinic where she sees up to 100 patients each day, said: I try to wash my hands with soap and water, and then apply moisturiser after handwashing in between patients instead of using alcohol rubs, which really hurt my skin.

If I have to use alcohol rubs or disinfectant wipes to clean the table counters at work, I will use the other hand, which is still holding up at the moment.

Tan said that her skin issues are not unique. Since the authorities stepped up on infection control measures, many of her colleagues have also been experiencing similar symptoms.

Tan said: Like me, the majority of my colleagues are also experiencing dry, itchy hands. However, I am honoured and proud to be in healthcare at this critical moment, so I will still carry on and do my part even though my hand eczema affects my lifestyle.

She has sought treatment at the skin centre itself. For now, she uses olive oil and hand cream, and wears cotton gloves at night after applying moisturisers to ease her severe skin dryness.

SANITISING HANDS 30 TO 50 TIMES EACH WORK SHIFT

Good hand hygiene helps prevent the transmission of infections such as Covid-19, but these preventive practices can also damage the skin.

Anecdotally, dermatologists approached by TODAY said that they are seeing a rising number of people with irritant eczema in the last two months all related to increased handwashing and overuse of harsh sanitising and disinfecting products.

Dr Mark Tang, senior consultant dermatologist at The Skin Specialists and Laser Clinic, said that skin issues related to over-washing and hand hygiene practices are an unavoidable reality for many people at the moment, particularly for healthcare and frontline workers.

He said that medical personnel must sanitise their hands after every patient encounter, which could be 30 to 50 times for each shift.

Being a little obsessive about hand hygiene is important and even life-saving at this time.

For those with a predisposition for hand or facial eczema, it is a very difficult time for them to balance the dilemma of maintaining hand hygiene and preventing eczema flares, Dr Tang said.

RASHES ON FACE FROM WEARING MASKS

Dr Tang has also encountered cases of facial rashes and mild pressure sores due to prolonged wearing of surgical or face masks.

The skin doctor, whose clinic is in Mount Alvernia Medical Centre, sees around two to three cases of hand rashes and one to two cases of facial rashes a week.

This does not include the many informal consultations he has when he encounters other healthcare workers in the wards and along corridors.

Dr Suzanne Cheng, senior consultant at the National Skin Centre, said that she has also noticed an increase in irritant eczema on the arms, legs and trunks due to frequent use of antiseptic body washes.

In particular, those with pre-existing eczema will suffer more because they already have a defective skin barrier, which makes their skin more sensitive.

DISRUPTING THE SKINS NATURAL B

ARRIER FUNCTION

Dr Cheng said that handwashing with soap and other aggressive disinfectants strip the skin of natural oils and damages the skin barrier.

When this is repeatedly done, it can cause skin dryness and flaking. In more severe cases, there is skin inflammation, itch, cracks and soreness.

Frequent use of an alcohol-based hand rub as well as disinfectant wipes and solutions for decontamination of high-touch areas has a similar effect, she added.

Even for those without pre-existing eczema issues, dermatologist Lynn Chiam from Children and Adults Skin Hair Laser Clinic said that certain ingredients found in hand sanitisers and detergents can disrupt the natural barrier function of the skin and strip away the skins natural oils and reduce its ability to protect itself.

The ingredients used in hand sanitisers that may affect the skin include various forms of alcohol, such as ethanol, n-proponol, isopropyl alcohol, chlorehexidine, hydrogen peroxides, quaternary ammonium derviatives, colorants and fragrances, Dr Chiam said.

So, although dermatologists see irritant eczema more commonly in people working in the healthcare and food sectors who must wash their hands more frequently, Dr Cheng from the National Skin Centre said that almost everyone now can develop the skin disease due to more vigorous hand hygiene practices to limit transmission of Covid-19.

Dr Chiam said that besides the healthcare sector, those working in the education and childcare sectors are more likely to sanitise and wash their hands more frequently as well.

In her practice, she has seen a 20 per cent increase in patients with hand eczema in the last two months. They range from young adults to parents of young children to the middle-aged group.

In severe cases, both hands are cracked, fissured and bleeding. It is painful (for them) to open their hands as the skin is so dry and painful, she said.

One of Dr Tangs patients, a 34-year-old auditor who did not want to be named, said that excessive handwashing in the last few months following the birth of her first child has worsened her hand eczema.

Right now, the dry and irritated skin around her joints has started to split spontaneously, which causes her a lot of pain.

I wash my hands even more these days, especially after I touch lift buttons or door handles. When well-meaning colleagues offer me hand sanitisers, Ill feel obliged to use them even though the alcohol rubs burn my skin so much that I feel like screaming when I use them, she said.

Dr Tang said that some of the more severe cases he has seen have infected areas with crusting and oozing. Tiny water vesicles (fluid-filled blisters) as well as swollen and inflamed nail folds can also develop.

These patients have constant itch that can affect their sleep. They also scratch incessantly, leading to further worsening of the inflammation and infection, he said.

CRACKED SKIN RAISES RISK OF ACQUIRING INFECTIONS

While good hand hygiene helps prevent transmission of infections, the experts warned that skin that is cracked and damaged could, ironically, put people at a higher risk of acquiring infections.

Dr Chiam said: Over-washing and over-disinfecting our hands can lead to excessive stripping away of natural oils on the skin, which are important components of the skin barrier. With a defective barrier function and cracks, tears in the skin from dryness, bacteria and viruses can enter the skin more readily.

Dr Tang said that although broken and fissured skin may increase the risk of bacterial infections and certain skin viruses such as the human papillomavirus that can cause warts, it does not increase ones risk of getting respiratory viral infections such as Covid-19 per se.

This is because respiratory viruses are usually transmitted via the respiratory tract or mucosal lining.

However, he pointed out that people with hand rashes may not adhere closely to hand hygiene practices due to their skin condition.

These lapses can increase their personal risk of getting infected. So, early prevention and treatment of hand rashes are vital in

our fight against the pandemic, Dr Tang said.

A GENTLE CLEANSER WILL WORK JUST AS WELL

For those prone to getting eczema or have active eczema, Dr Cheng of the National Skin Centre advised avoiding or minimising contact with irritants such as soap, disinfectants, detergents and alcohol-based wipes and rubs.

Use a gentle, soap-free, fragrance-free cleanser instead. Ensure there is easy access by putting a bottle by the sink, shower room and at your workplace toilet.

A cleanser does not need to be antibacterial or industrial-strength to clean skin and remove dirt, bacteria and viruses, she emphasised.

She also cautioned against using hot water to wash hands or shower because it can worsen skin conditions. The temperature of the water used for handwashing does not impact the removal of germs such as bacteria or viruses that cause diseases.

Associate Professor Hsu Li Yang, programme leader for infectious diseases and the co-director of global health at NUS Saw Swee Hock School of Public Health, said that regular handwashing works best to clean hands, but added that a hand sanitiser is useful when a tap is not readily available.

Regular soap is sufficient to pry apart the envelope of viruses such as Sars-CoV-2, which causes Covid-19, while water additionally washes away the virus particles, which does not happen with hand sanitiser, Associate Prof Hsu said.

He explained that most of the active ingredients in hand sanitisers available will work against the coronavirus, particularly those containing alcohol above 60 per cent concentration.

However, cleansers marketed as antibacterial offers no advantage against viruses, he said. They act against bacteria instead. Today Online

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Scientists identify a protein that switches on allergic itching – New Atlas

Posted: at 5:52 pm

Incessant itching is a harsh and problematic reality for eczema sufferers, causing all sorts of problems that can range from skin infections to trouble sleeping. Scientists investigating the biological processes behind the condition have uncovered a protein in the skin they say acts as a switch for itch-related neurons, offering a potential new target in the ongoing search for more effective treatments.

A number of factors can cause outbreaks for eczema sufferers, including irritants, reactions to certain foods, and allergies. The itching sensation, which often goes with other symptoms such as dryness and redness, is driven by neurons in the skin, which take their cues from sensory cells based at the root of the spinal nerves.

Researchers at North Carolina State University have been examining this pathway through experiments on mice, in which they chemically induced cases of eczema. When exposing the animals to common allergens such as dust mites, the scientists observed an increase in a skin protein called periostin, which served to greatly exacerbate the itch response.

We have found that periostin, a protein that is produced abundantly in skin as part of an allergic response, can interact directly with sensory neurons in the skin, effectively turning on the itch response, says Santosh Mishra, lead author of a paper. Additionally, we identified the neuronal receptor that is the initial connection between periostin and itch response.

The receptor protein, called v3, is expressed in the skin's sensory neurons and acts as the connector for periostin in driving the increased itch response. The team found that by switching off the receptor, they could break this important chain and significantly reduce the severity of the itching.

Periostin and its receptor connect the skin directly to the central nervous system, Mishra says. We have identified the first junction in the itch pathway associated with eczema. If we can break that connection, we can relieve the itch.

The research was published in the journal Cell Reports.

Source: North Carolina State University

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Do You Have ‘Iso Skin’? Why Your Face Is Freaking Out And How To Fix It – 10 daily

Posted: at 5:51 pm

If you thought self isolation was going to give you gloriously fresh skin, you wouldn't be the only one.

And why wouldn't you? Surely weeks and weeks without makeup would mean our skin would see the benefits of working from home. But as we enter week three of self isolation, turns out it's actually quite the opposite.

Many women are seeing an increase in skin related troubles, from breakouts, to dryness and irritation dubbed 'iso skin'. Like we don't have enough things to worry about during the coronavirus pandemic, now we have skin woes to add to our ever growing list.But why?

According toDr Vivek Eranki, a leading Australian cosmetic surgeon and head of Australian Cosmetic, spending timeindoors is linked to vitamin D deficiency as well as increased exposure to artificial and dry air. And it's these two factors combined that are causing our skin to throw a bit of a tantrum.

"Skin is the body's largest organ and vitamin D deficiency accelerates its ageing. Not getting enough sun also lowers immunity and increases flare ups of autoimmune conditions such as eczema, psoriasis and atopic dermatitis,"Dr Eranki told 10 daily.

The artificial air that comes from our air conditioners and heaters further removes the moisture from our skin, causing it to dry out.

"Skin has to maintain its moisture levels to look good, but also to heal. Dry skin increases the risk of flare ups of eczema and other skin conditions and makes your skin more susceptible to infections,"Dr Eranki added.

Other factors including stress, poor diet and lack of exercise while we spend more time at home can further exacerbate these skin issues. Here's what you can do to get your skin back to normal:

You might be tempted to up your usual skincare routine while you're at home, especially if your skin is currently freaking out. We're talking about applying a face mask everyday and a plethora of serums.

Dr Eranki said this is a big no-no and likely causing your skin to spin out of control even further, the exact opposite of what you're trying to achieve.

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"When patients overdo their skin care regime, it inhibits the protective features of your skin. This has an opposite effect and causes flare ups of acne and eczema," he said.

So remember in primary school when your teacher used to tell you slow and steady wins the race? Turns out it's the same when it comes to skincare: sticking to a basic routine is usually best.

While you might want to give yourself a DIY facial or treatment,Dr Eranki advised being careful about what you try without clinical advice while beauty based businesses are closed due to restrictions.

"Some patients might be prescribed beauty treatments such as peels and dermal rollers for home use. This is patient-specific and may only apply for certain problem areas for that patient for a length of time," he said.

"Using these treatments without direction from a professional could be detrimental to your skin."

Being in isolation might lead you to eat more takeaway than you regularly do. While it's okay to have a treat every now and then,Dr Eranki said a healthy diet is important in maintaining good skin.

"While in isolation, reacquaint yourself with cooking healthy and hearty meals with lots of vegetables," he suggested.

Exercise can also help to manage the stress you might be feeling during this time, which aside from impacting our mental health, can also be bad for our skin.

"Aim to exercise for 30 minutes a day and clear your mind by dealing with things that you have been avoiding because you have no time and it will help you mentally de-clutter."

While you might think you can skip your usual sunscreen because you are inside,Dr Eranki encourages you to make sure you are still applying a suitable amount of SPF to avoid skin ageing as well as cancers.

"When near a window, I always recommend patients use a barrier sunscreen to protect themselves against UV-A and UV-B rays," he said.

"I suggest using a barrier sunscreen rather than a chemical sunscreen because they physically block UV light and are much safer than chemical sunscreens."

The best thing you can do to help your skin get back to its normal condition is to have a good skincare routine, with the first step being investing in a good soap and moisturiser.

"Use a good soap that doesnt completely strip away your natural oils on your skin and then make sure the moisturiser is emollient based and fragrance free,"Dr Eranki said.

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You should moisturise both morning and night and match your products to the time you use them.

"For patients with naturally oily skin, a serum works well to hydrate and protect and for those with more dry complexions, they would benefit from a lotion or cream."

Once the basics are covered, it's time to turn your attention to a good exfoliant that will remove dead skin layers and build up of grime. It will also help your skincare topenetrate more deeply, providing better nourishment to your skin cells.

"Frequency of exfoliating is very important. If your skin is currently inflamed or sensitive, do not exfoliate until it has healed. Once it has healed, gently exfoliate once a week,"Dr Eranki said.

"For normal or dry skin, I recommend exfoliating one to two times per week. For oily skin, I suggest you exfoliate two to three times per week."

When it comes to looking for a good exfoliant,Dr Eranki suggests opting for one with organic plant-basedingredients such as fruit enzymes, rhassoul clay, finely ground oats and non-abrasive walnut shell.

"These work in harmony with the natural physiology of your skin, encouraging the skins natural renewal process."

Vitamin A is an natural essential nutrient that supports skin and immune system that stimulates the production of new skin cells and is readily absorbed into the skin when you apply it topically.

If you don't have enough Vitamin A, your skin can become dry or a deficiencycan cause 'follicular hyperkeratosis' -- a condition marked by too much keratin in the hair follicles.

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According to Dr Eranki, this can cause raised papules to form on your skin.

That's why aside from including Vitamin A in your skincare routine, it's important to eat diet rich in the vitamin when you're in self isolation to help your skin along.

"Foods rich in Vitamin A include salmon, beef liver, dairy products, eggs, fish, cod liver oil and shrimp,"Dr Eranki said, adding that Vitamin A is a godsend for those suffering from acne.

Vitamin A further stimulates collagen production, which makes it effective in reducing the appearance of fine lines and wrinkles and it can also help to even out skin tone by fading age spots.

Vitamin C is an anti-oxidant that triggers the skin to heal itself when applied topically, which accelerates theproduction of collagen and elastin.

"Collagen and elastin are both naturally occurring protein fibers that help keep skin plump and firm. So in helping to promote collagen production, topical vitamin C can help prevent premature aging of the skin,"Dr Eranki said.

Another benefit of Vitamin C is itinhibits your skin's melanin production, which would otherwise lead to skin discoloration, dark spots and hyperpigmentation.

As Vitamin C is not stored in your body, eating foods rich in it, such as oranges, is important and will also assist with immunity.

Featured image: Getty

Do you have a lifestyle story or personal experience to share with us? Reach out and tell us about it at vtodoroska@networkten.com.au

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