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Category Archives: Transhuman News

Illumina and GenoScreen Partner to Expand Access to Genomic Testing for Multidrug-Resistant Tuberculosis – PR Newswire

Posted: October 19, 2022 at 2:39 pm

Transformative alliance will help advance the World Health Organization's strategy to end the global TB epidemic by 2035

SAN DIEGO, Oct. 18, 2022 /PRNewswire/ -- Illumina Inc. (NASDAQ: ILMN), a global leader in DNA sequencing and array-based technologies, and GenoScreen, an innovative genomics company, today announced a partnership to accelerate progress to end tuberculosis (TB) worldwide. The partnership will expand capabilities for countries most impacted by tuberculosis to more effectively detect and combat multidrug-resistant TB (MDR-TB). This alliance will enable global access to a package combining Illumina sequencing products and the GenoScreen DeeplexMyc-TB assay, a targeted next-generation sequencing (NGS) based test for rapid and extensive detection of anti-TB drug resistance, to promptly inform treatment decision. This will help advance the World Health Organization's (WHO) strategy to end the global TB epidemic by 2035.

"Through our partnership, we will enable lower-income countries to confront the pervasive threat of TB and work toward eliminating it," said Phil Febbo, chief medical officer of Illumina. "The COVID-19 pandemic response led to expanded NGS capacity around the world, so now institutions have the platforms needed to support testing for TB drug resistance and improve survival for patients with TB, the leading infectious disease killer prior to COVID."

According to the WHO, TB is the first worldwide bacterial infectious killer, claiming over 1.5 million lives each year. And even though TB can be cured when appropriately treated, MDR-TB represents a global public health emergency. In 2019, an estimated 465,000 people developed TB with rifampicin resistance (RR) or MDR, yet only 40% of these cases were detected and enrolled on MDR-TB treatment. Due to the COVID-19 pandemic in 2020, deaths from TB increased for the first time in a decade.

"As a world specialist in TB genomic solutions, we envision this partnership with Illumina as an accelerator for the global deployment of our DeeplexMyc-TB assay, especially for countries with the highest needs," said Andr Tordeux, CEO of GenoScreen.

Standard culture-based testing methods currently incur turnaround times of up to two months, and conventional molecular assays are limited in identifying drug resistance. The combined use of the GenoScreen DeeplexMyc-TB assay and the Illumina NGS platformsallows much more rapid determination of extensive drug resistance profiles and TB strain types affecting patients.

The DeeplexMyc-TB assay, developed and produced by GenoScreen since 2019,usesa culture-free approach to identify TB mycobacteria and more than 100 non-TB mycobacterial species, and to predict resistance to 15 antibiotics, in 24 to 48 hoursdirectly from primary respiratory samples. The Deeplex web application for automated analysis of the sequencing data enables clinicians to easily interpret the results and best define personalized treatments.

"The DeeplexMyc-TB kitis the most comprehensive commercial molecular test for detection of anti-TB-drug resistance available to date," said Philip Supply, research director at the French National Centre for Scientific Research. "We are continually updating the technology to detect emerging resistance to the newest anti-TB drugs."

Implementing NGS testing will also benefit national TB programs around the world by providing critical surveillance data about resistance to different anti-TB drugsimportant information for high-burden countries to guide TB control strategies.

Use of forward-looking statementsThis release may contain forward-looking statements that involve risks and uncertainties. Among the important factors to which Illumina's business is subject that could cause actual results to differ materially from those in any forward-looking statements are challenges inherent in developing, manufacturing, and launching new products and services, and Illumina's ability to successfully partner with other companies and organizations to develop new products, expand markets, and grow its business, together with other factors detailed in Illumina's filings with the Securities and Exchange Commission, including its most recent filings on Forms 10-K and 10-Q, or in information disclosed in public conference calls, the date and time of which are released beforehand. Illumina undertakes no obligation, and does not intend, to update these forward-looking statements, to review or confirm analysts' expectations, or to provide interim reports or updates.

About IlluminaIllumina is improving human health by unlocking the power of the genome. Our focus on innovation has established us as a global leader in DNA sequencing and array-based technologies, serving customers in the research, clinical, and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture, and other emerging segments. To learn more,visitillumina.comand connect with us onTwitter,Facebook,LinkedIn,Instagram, andYouTube.

Investors:Salli Schwartz858-291-6421[emailprotected]

Media:Samantha BealUS: 714-227-2661[emailprotected]

GenoScreen Contact:Pierre Burguire[emailprotected]

SOURCE Illumina, Inc.

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Superresolution Method Poised to Better Gene Function Understanding – Photonics.com

Posted: at 2:39 pm

BARCELONA, Oct. 18, 2022 An interdisciplinary team from the Centre for Genomic Regulation (CRG) and the Institute for Research in Biomedicine (IRB Barcelona) has developed an imaging technique that captures the structure of the human genome to reveal how individual genes fold at the nucleosome level the fundamental units constituting the genomes three-dimensional architecture. The technique integrates superresolution imaging with advanced computational modeling.

According to the researchers, the method allowed them to image the structure of the human genome at unprecedented resolution. They believe the technique could have a long-term impact on scientific discovery.

Scientists used the technology, called Modeling immuno-OligoSTORM (MiOS), to create and virtually navigate 3D models of genes. Since almost every human disease has some basis in genes, the ability to visualize how genes work could lead scientists to a better understanding of how genes affect the health of the human body. The developers of MiOS hypothesized that taking superresolution microscopy and merging it with advanced computational tools could be a way to image genes at the level of detail necessary to study their shape and function, so as to fully understand their function and regulation.

MiOS showed the distribution of nucleosomes within specific genes in superresolution, through the simultaneous visualization of DNA and histones. It integrated this information with restraint-based and coarse-grained modeling approaches. It allowed quantitative modeling of genes with nucleosome resolution and provides information about chromatin accessibility for regulatory factors such as RNA polymerase II.

According to researcher Juan Pablo Arcon, the method provided a picture, or movie, of the 3D shape of genes at resolutions beyond the size of nucleosomes, reaching the scales that are needed to understand in detail the interaction between chromatin and other cell factors.

We show that MiOS provides unprecedented detail by helping researchers virtually navigate inside genes, revealing how they are organized at a completely new scale, researcher Vicky Neguembor said. It is like upgrading from the Hubble Space Telescope to the James Webb, but instead of seeing distant stars well be exploring the farthest reaches inside a human nucleus.

In the future, observations on genetic information obtained through MiOS could be used to catalog variations in the shape of genes that cause disease, for example. MiOS could also be used to test drugs that may be able to treat a disease by changing the shape of an aberrant gene.

The researchers intend to develop MiOS further, adding additional functionality that can, for example, detect how transcription factors (i.e., proteins involved in the process of transcribing DNA into RNA) bind to DNA.

The research was published in Nature: Structural & Molecular Biology (www.doi.org/10.1038/s41594-022-00839-y).

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Space Station 14: Multiplayer Disaster Simulator – SS14

Posted: October 17, 2022 at 10:58 am

Space Station 14 tells the story of an ordinary shift on a space station gone wrong. Immerse yourself into your role, tinker with detailed systems, and survive the chaos in this round-based multiplayer role playing game.

Your custom character can spawn as one of dozens of crew and enemy jobs, ranging from engineer to captain, or even a traitor, each with its own unique gear. Your duties guide you through rich interactions with complex mechanics, whether you're managing your inventory, setting up the reactor, or flushing yourself down the disposal tubes.

As disaster, incompetence, and sabotage strike the station, the tension rises - opening up emergent situations that force you to make hard choices. Will you patch up the medical bay after an asteroid punches a hole in it, or fight for control when the captain gets murdered by revolutionaries? Do you break out an unjustly imprisoned clown, or sit back at the bar and serve drinks without a care in the world?

The story of the station's collapse is in the hands of its players, and each round is an intense, immersive experience that will leave you wanting more.

SS14 is a remake of the cult classic Space Station 13. The game is under active development and completely open source. Anybody can contribute, even you!

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Four astronauts return to Earth after nearly 6 months on the Space Station – NPR

Posted: at 10:58 am

The SpaceX Crew Dragon Freedom capsule splashes down Friday in the Atlantic Ocean off Florida in a return trip from the International Space Station. Bill Ingalls/NASA via AP hide caption

The SpaceX Crew Dragon Freedom capsule splashes down Friday in the Atlantic Ocean off Florida in a return trip from the International Space Station.

CAPE CANAVERAL, Fla. Four astronauts returned to Earth in a SpaceX capsule Friday, ending their nearly six-month space station mission with a splashdown in the Atlantic off Florida.

Wet and windy weather across Florida delayed their homecoming. SpaceX and NASA finally gave the all-clear on Friday, and the three Americans and one Italian departed the International Space Station, their residence since April.

The capsule parachuted into the ocean, just off Jacksonville, Florida, about five hours after it left the space station. It carried NASA astronauts Kjell Lindgren, Bob Hines and Jessica Watkins, the first Black woman to complete a long-term spaceflight, and the European Space Agency's Samantha Cristoforetti. SpaceX delivered their replacements last week.

Before checking out, the astronauts said they couldn't wait to have a cold drink with ice, eat some pizza and ice cream, take a shower, revel in nature and, of course, reunite with their families. NASA planned to hustle them to Houston once they were off SpaceX's recovery ship and back on solid ground.

"Getting the first few hugs when we get back is really going to be awesome," Hines told reporters earlier in the week.

Remaining aboard the space station are three Americans, three Russians and one Japanese.

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Four astronauts return to Earth after nearly 6 months on the Space Station - NPR

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Just Look Up: How to Track the International Space Station – PCMag

Posted: at 10:58 am

Have you ever looked up at the sky, at dawn or dusk, and seen a bright spot moving swiftly across the sky? It's not a new star shifting out of sequence. Chances are you just saw the International Space Station (ISS).

At 357 feet end-to-end, the ISS is a football field-sized orbital microgravity, solar-powered research laboratory, training facility, and observatory. It travels at 17,500mph, 250 miles above our heads, and orbits the Earth every 90 minutes. If its hard to imagine how fast that is, an airplanes top speed is 575mph.

Contrary to popular belief, the ISS is not the first place humans have ever lived outside of planet Earth (that was NASAs Skylab(Opens in a new window), which orbited the Earth from 1973-1979), but it's a crucial stepping stone toward human space exploration, and our species future habitats on other planets.

If you want to know how to track the ISS, weve got you covered. Here's how to check out NASAs interactive map and sign up for email or text alerts to know the best time to look up.

If you want to track the ISS from home, go to Spot The Station(Opens in a new window) and use the interactive map to find sighting opportunities in your area. There is also the Live Space Station Tracking Map(Opens in a new window), which shows the physical location of the satellite over the Earth.

Potential sightings are marked by blue pins on the map. I live in Los Angeles, so the nearest blue pin on the map is to the Northeast of the city, high up in the San Gabriel Mountains, at Mount Baldy.

Sighting Location map(Credit: Spot the Station)

You can select a blue pin and click the View sighting opportunities link to see when the ISS could be seen from that spot. The data is precise, showing the exact day, time, elevation, and duration of ISS sighting in minutes. NASA also provides links to share each potential sighting occasion via Facebook and Twitter.

All sightings will occur within a few hours before or after sunrise or sunset. This is the optimal viewing period as the sun reflects off the space station and contrasts against the darker sky. Before heading out to any single spot, it should be noted that the ISS needs to be at an elevation of above 40 degrees from the horizon in the nights sky or you wont see anything.

You can also sign up for alerts(Opens in a new window). Click the Sign Up button in the Heads Up Alerts section, and enter your general location by selecting a blue pin on the map and clicking Sign up for this location.

Choose if you want email or text notifications, then enter your email address or mobile carrier and number. Choose whether you want AM or PM alert times, check the boxes so you can agree to the terms, and click Submit. NASA requires a double opt-in to their alerts service. Once you provide the information above, you will receive an 8-digit code (so keep an eye out for it).

Once your code arrives, return to the sign up page and look to the Enter your Code section on the right of the screen. Enter your email or number, and add the code you were sent. Click Process Code to complete the registration process.

The site will then confirm your alerts are active. Check that all the data is correct, with your preferred location (i.e. mine is Mount Baldy as thats the closest one to Los Angeles). This page will also give you the current months sighting options, in your local time zone.

NASA will then notify you when the ISS is in your area and within optimal viewing conditions.

If you opted to receive emails, dont forget to add [emailprotected] to your contacts so you can avoid the notifications slipping into your spam folder. Your alerts will continue to ping your phone or inbox for a year. After that, you will need to sign up again.

The seven-member crew of Expedition 68(Credit: NASA)

Whats life like aboard the ISS? We interviewed astronaut Nicole Stott in 2018 during the press tour for NatGeos One Strange Rock(Opens in a new window). She told us about her 27-year career at NASA, spending 104 days in space and performing a six-hour and 39-minute spacewalk, then returning to Earth on Space Shuttle Discoverys final descent.

Whos up there now? At the time of writing, there are seven astronauts onboard(Opens in a new window), including Nicole A. Mann, the first indigenous woman from NASA to go to space.

There are also robots aboard the ISS. These Astrobee robots are designed to track radiation levels, assist in two-way communications with mission control on Earth, and keep well out of the way of astronauts running experiments.As of April 2022, the Astrobee program "has operated over 750 hours on the space station, completing over 100 activities, from tech demonstrations to assisting in experiments," NASA says(Opens in a new window).

The European robotic arm extending from the Nauka multipurpose laboratory module(Credit: NASA)

If youre an optimist, the ISS is welcome evidence that we can all play nicely together when we have common goalslike, say, the future of life itself. According to the ISS National Laboratory(Opens in a new window), 240 people from 19 countries have visited the station, which has hosted more than 3,000 research investigations from researchers in more than 100 countries.

Not a spoiler alert but, in about 5 billion years, our Sun will die(Opens in a new window), so our descendants need to be long-gone by then. In order to explore the known universe, we need to find out how to equip humans for (very) long distance travel, and learn how they can survive in (extremely) hostile environments.The ISS serves as a micro-gravity testbed for technologies that will enable this.

One of those experiments is the Alpha Magnetic Spectrometer (AMS)(Opens in a new window), a 7.5-ton module containing the first precision particle physics detector in space. We previously spoke with Dr. Samuel Ting, the scientist in charge of the AMS, to find out how it's been sifting space," modeling billions of cosmic rays, and looking for evidence of dark matter, all to discover the origins of the universe.

Other experiments(Opens in a new window) being conducted on the ISS range from biology and biotechnology investigations, to space science (such as experimental chrondule formation, or stardust) and evidence-based human research, including identifying genetic predispositions to physical shifts within microgravity environments.

SpaceX Crew-5 Mission Specialist Anna Kikina from Roscosmos(Credit: NASA)

The ISS was constructed in situi.e. above the Earths atmosphere. The first module launched on Nov. 20, 1998, and the first crew went up on Oct. 31, 2000. Since its inception, 16 countries have been involved, under the cooperation of five space agenciesCSA (Canada),ESA (Europe), JAXA (Japan), Roscosmos (Russia), and NASA (United States).

In a time of heightened conflict between major players on Earth, its remarkable that everyone involved manages to remain beyond such strife and get on with the job at hand, for the most part. That said, Russia is leaving the ISS at some point this decade, and China is currently building a space station of its own.

Blue Origin NS-22(Credit: Blue Origin)

On a sadder note, the ISS itself will be decommissioned in 2030, so its worth making time to spot it in the nights sky at least once before it goes.

Although not a short read, NASAs transition plan details(Opens in a new window) how the station will be developed for commercial use in the future, with steps being taken to develop both the supply and demand side of the low-Earth orbit commercial economy, and the technical steps and budget required for transition.

For those of us who long to be space tourists, and not just spot space stations from the ground, the transition report confirms that NASA has signed agreements with Blue Origin, Nanoracks LLC, and Northrop Grumman to develop commercial destinations in space.

Until then, look up and imagine what life will be like when we can all go into Low Earth Orbitand then where no human has gone before, boldly or otherwise.

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The Russian Space Program Is Falling Back to Earth – The Atlantic

Posted: at 10:58 am

The new crew arrived at the International Space Station last week, all smiles and floating hair. There was, as usual, a little welcome ceremony, with heartfelt remarks from the newcomers streamed live for the people they left behind on Earth. A few of the astronauts floated above the others and turned upside down, hanging like bats, so that their beaming faces would fit into the frame.

But this latest trip was different: For the first time, a Russian cosmonaut had traveled to the space station on an American SpaceX capsule launched into orbit from Florida. The ride was the result of a new seat-swapping arrangement between the United States and Russia. Before 2020, when NASA started using SpaceX to reach the ISS, the space agency had relied solely on Russias astronaut-transport system, the Soyuz, paying millions of dollars a seat. Now American astronauts will fly on Soyuz, and Russian cosmonauts on SpaceX, with no money exchanged between the two countries.

The Russian and American space programs have been tangled up since the beginning, and they remain tethered now, even as relations between the two countries deteriorate because of the ongoing war in Ukraine. The two have no choice but to work together: The ISS is a shared space, with the U.S. and Russia its largest partners and Russia responsible for maintaining the stations orbit.

Beyond the ISS, though, Russias space portfolio isnt all that grandiose these days. Although cosmonauts fly into orbit regularly, Russia does not have a rover on the far side of the moon, as China has, or orbiters around Mars, as India and the United Arab Emirates have. It does not have a fleet of space telescopes like the U.S has. The Soviet Union was the first to send a human being to space, decades ago, and its early accomplishments are a distinct point of national pride. But the Russian space program has stalled for years, plagued by sparse budgets. And that was before Vladimir Putins onslaught on Ukraine: Some of the space plans the country still had in the works are falling apart. Now the Russian space effort may be more adrift than ever.

All of the satellites around Earth, thousands and thousands of them, whether the navigation kind or the spying type, can trace their history to Sputnik. When the Soviet Union launched the first artificial satellite into orbit 65 years ago, it ushered in a new era of technologyand set the tone for the space race. Within a couple of years, the Soviet Union had started launching spacecraft to the moon, where they intentionally crashed into the surface, sprinkling hardware across the regolith in a very explosive first. In 1961, Yuri Gagarin became the first human to travel to space, beating Americans to the milestone by less than a month. But by the end of the decade, the U.S. had effectively won the race: When American astronauts launched to the moon, the Soviet Union was still trying to figure out how to stop its rocket from exploding.

Read: The Russian invasion touches outer space

In the following years, the Soviets put the first-ever lander on Mars, which transmitted for about 20 seconds before cutting out, and sent a series of missions to Venus. They built their own space shuttle, which flew only once, and built a space station that operated for 15 years before being ditched into the sea. The fall of the Soviet Union led to a decreased influence on the world stage, but Russia remained a key player in space. By 1998, Roscosmos, the post-Soviet space agency, was helping the U.S. assemble the ISS piece by piece. For years, it was the only nation capable of flying people to the ISS.

These space successes have become a meaningful part of Russias national identity. Space exploration is one of the two reference points in recent historythe other being the Soviet Unions victory in World War IIthat enjoys a broad consensus among Russians and defines many features of Russian political culture, Pavel Luzin, a Russian space-policy analyst, has written. In recent years, after Russias takeover of Crimea and the resulting international backlash, the effort has become less innovative and more militarily focused, while lacking a clear future direction, James Clay Moltz, a professor of national-security affairs at the Naval Postgraduate School in California, has written. Last year, Russia conducted a missile test to blow up a defunct satellite, producing debris that passed dangerously close to the ISS. The space program is also running on a dwindling budget. Russia is struggling to find a formula for space success in the 21st century, Moltz wrote in 2020.

Russias full-on invasion of Ukraine has only made matters worse. The fallout from the war has narrowed the countrys space portfolio even more; sanctions have included U.S. measures meant to degrade their aerospace industry, including their space program. Russia has long hoped to rekindle its moon efforts, and eventually put people on the surface, but the European Space Agency, its partner in the effort, has withdrawn its participation because of the war in Ukraine. Europe has also kicked Russia out of the effort to send a new rover to Mars to search for signs of ancient life. National space organizations and private space companies alike have dropped Russian launch services on more than a dozen occasions, seeking other providers. Russia risks being left behind completely in the increasingly competitive commercial space-launch market, Jeremy Grunert, an Air Force lawyer who specializes in military and space law, wrote recently.

Read: Maybe dont blow up satellites in space

Roscosmos seeks to strike out on its own in low-Earth orbit and build a new space station, with the first module launching sometime in 2028, and more going up in 2030the year the U.S. wants to start winding down the ISS. But sanctions have hindered development of Russias space-station hardware, which has to be redesigned, as there will be no access to the Western electronics that the designers initially had in mind, Luzin wrote. It is obvious that the Russian orbital station project is both very ambitious and largely unfeasible given the current circumstances. At a press conference held last week after the cosmonaut Anna Kikina launched on SpaceX, Sergei Krikalev, a former cosmonaut who serves as the executive director of Roscosmoss human-spaceflight program, told reporters, We know that is not going to happen very quick. Russia, he said, could discuss extending our partnership in ISS.

If Russia were to jump ship early, it would have no spaceflight program to speak of. We must bear in mind that if we discontinue manned flights for several years, it will be very difficult to restore what we have achieved afterwards, Vladimir Solovyov, a former cosmonaut and the flight director for the Russian side of the ISS, said in a Roscosmos interview this summer. So Russia is likely to stay on the ISS for as long as possible, especially as the rest of its space endeavors wither. Not all of Russias space goals have been thrown into doubt. The country is working with China to build a lunar base by the 2030s. Although China has called for Russia to end its war on Ukraine, it has expressed support for their future cooperation in space exploration.

Read: Why the far side of the moon matters so much

After Kikina arrived on the ISS last week, blasting off in an American-built capsule, sleeker and more spacious than the Russian Soyuz, I wondered whether she might say something about whats going on in her home country. We shouldnt assume that any professional spacefarer shares the beliefs of her president, although earlier this year, a trio of cosmonauts had posed for pictures on the ISS with a flag in support of pro-Russian separatists in Ukraine (NASA responded by saying that it strongly rebukes the display). But Kikina, the sole woman in Russias cosmonaut corps, just thanked her family and the crews she worked with, and held up a little handmade doll as tribute to her hometown of Novosibirsk. Meanwhile, 250 miles below, the war raged on, weakening Russias standing as a spacefaring nation.

A force that dominated the early days of humanitys drive to reach the stars, that set the pace for the history books, now risks flaming out because of a land war back on Earth. In the coming years, Russia may no longer be considered a space power at all; in fact, some observers are making that assertion now.

Russias space future matters deeply to Russia itself, of course, but it also concerns the rest of the word. The country, uncomfortable in the shadow of other space powers, could double down on its military uses of space, threatening an already precarious arena. And while space exploration is an image-bolstering activity, it has consequences that transcend national bordersilluminating discoveries about the universe and our place in it, and remarkable demonstrations of what human beings can do with a little bit of rocket fuel and some curiosity, in the skies above Earth and well beyond. With Russias potential downfall as a space power, humanitys potential in the cosmos may shrink, and a once-formidable participant that could have propelled exploration of the cosmos further will be left out of the endeavor instead.

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Best bits from returned astronauts space station mission – Digital Trends

Posted: at 10:58 am

SpaceXs Crew-4 astronauts returned safely to Earth on Friday after a six-month stint living and working aboard the International Space Station.

One of those astronauts was Samantha Cristoforetti. The Italian space traveler on her second orbital mission shared moments from the adventure with her more than one million Twitter followers and 780,000 TikTok fans, posting photos and videos showing life aboard the orbital outpost, along with plenty of stunning imagery of Earth 250 miles below.

Heres a selection of Cristoforettis tweets posted during her half-year space mission.

First, a quick review of the trip up and the first few days in space:

Back on the International @Space_Station (and TikTok) pic.twitter.com/oCgJSdWKcu

— Samantha Cristoforetti (@AstroSamantha) May 6, 2022

A breathtaking view of the moon:

The ethereal beauty of the Moon the last sliver of the waning crescent rising above the colors of the imminent sunrise. #Moon #MissionMinerva pic.twitter.com/bwza4TTlCt

— Samantha Cristoforetti (@AstroSamantha) May 30, 2022

Cycling in space:

Happy #WorldBicycleDay from the International @Space_Station! #MissionMinerva #SpaceTok pic.twitter.com/gTepsRjtdR

— Samantha Cristoforetti (@AstroSamantha) June 3, 2022

Taking time out to replicate a moment from Gravity:

One of my biggest regrets from my year in space was watching #GravityMovie and having @AstroSamantha float by the screen after her working out and not being quick enough to the camera. Heres the original photo fail. So disappointed then, but all is good now. Thank you, Samantha! https://t.co/4Av29VmDNl pic.twitter.com/XRJA21jjCA

— Scott Kelly (@StationCDRKelly) June 19, 2022

Moroccan culture is known for its impressive art and architecture, says Cristoforetti. No wonder that it looks like a real piece of EarthArt from space too!

Moroccan culture is known for its impressive art and architecture. No wonder that it looks like a real piece of #EarthArt from space too! #MissionMinerva #Morocco #Maroc #AtlasMountains pic.twitter.com/725JWVVHUK

— Samantha Cristoforetti (@AstroSamantha) July 8, 2022

Heres how astronauts on the station capture all of those amazing Earth shots:

How to take pictures in #space! #worf #SpaceTok #MissionMinerva @esa @esaspaceflight pic.twitter.com/IiCnUog6Ru

— Samantha Cristoforetti (@AstroSamantha) July 13, 2022

Getting ready for bed on the ISS:

Getting ready for bed! #BedtimeRoutine #SpaceToc #MissionMinerva @Space_Station @esa @esaspaceflight pic.twitter.com/MwWSxSjz2H

— Samantha Cristoforetti (@AstroSamantha) July 15, 2022

Heres an entertaining effort by the Crew-4 astronauts:

Formation flying into our 4 little crew quarters. We made it on the first try well, maybe the second Volo in formazione fino ai nostri 4 piccoli alloggi. Riuscito al primo tentativo beh, forse al secondo #MissionMinerva #Exp67 @Space_Station @esa @esaspaceflight pic.twitter.com/gP3ElkxqLW

— Samantha Cristoforetti (@AstroSamantha) July 16, 2022

Do astronauts take Vitamin D while staying on the ISS? Heres the answer:

Do you need to have #VitaminD supplements? #AskMe #MissionMinerva #SpaceTok @esa @esaspaceflight pic.twitter.com/hrmuI7fPhY

— Samantha Cristoforetti (@AstroSamantha) July 18, 2022

A time-lapse showing the space stations solar arrays tracking the sun:

A soothing solar array waltz in this accelerated timelapse arrays rotate on two axes to track the sun. And our #robotics teams on the ground have been busy installing the MISSE material science experiment can you see the robotic arm moving? #MissionMinerva pic.twitter.com/A1Lgk2Tftk

— Samantha Cristoforetti (@AstroSamantha) August 9, 2022

Here we can see an impact crater on Earth that occurred some 300 million years ago:

We explore space, and sometimes space comes to us. This visit if from over 300 million years ago the Gweni-Fada #meteorite impact crater in Chad 14 km in diameter! #MissionMinerva pic.twitter.com/x5i0CkXexP

— Samantha Cristoforetti (@AstroSamantha) August 11, 2022

Aurora are a common sight for astronauts on the space station:

The Sun has been really active lately. Last week we saw the most stunning auroras I have ever experienced in over 300 days in space! #auroraaustralis #MissionMinerva pic.twitter.com/r9hzZSoMNp

— Samantha Cristoforetti (@AstroSamantha) August 21, 2022

Prepping a meal in space:

Preparing lunch on the @Space_Station. Balanced meals, like this one, help me to stay healthy and maintain strong muscels and bones in space. #MissionMinerva #SpaceTok @iofbonehealth @esa pic.twitter.com/FQWvha7RFA

— Samantha Cristoforetti (@AstroSamantha) August 25, 2022

Stars from the ISS:

Twinkle, twinkle, little star actually, on @Space_Station we gaze at the stars from above the atmosphere, so no, they dont twinkle. Also, we dont have to worry about clouds @esa pic.twitter.com/tqjyeK2q4z

— Samantha Cristoforetti (@AstroSamantha) August 29, 2022

The amazing Andes, as seen from space:

A pass over the Andes just before sunset. Love the long shadows over the mountains! #MissionMinerva pic.twitter.com/wNvTaEt6TC

— Samantha Cristoforetti (@AstroSamantha) August 28, 2022

Watching other astronauts come to space:

We had a spectacular view of the #Soyuz launch! Sergey, Dmitry and Frank will come knocking on our door in just a couple of hours looking forward to welcoming them to their new home! #MissionMinerva pic.twitter.com/b6PP8L6AEl

— Samantha Cristoforetti (@AstroSamantha) September 21, 2022

A little science demonstration in microgravity conditions:

What do you think happens to the ping pong ball when I try to sink it in water? Find out! #MissionMinerva #bouyancy #SpaceTok @esa @esaspaceflight @Space_Station pic.twitter.com/dtxW8AOtlS

— Samantha Cristoforetti (@AstroSamantha) September 24, 2022

Yoga in space is tricky but possible:

Yoga in weightlessness? Done!Its a bit tricky, but with the right poses (thanks @CosmicKidsYoga!) and some creative freedom you can do it. Take a look! https://t.co/XXEOcFzg4L#MissionMinerva #CosmicKids https://t.co/H2hGPSAWmD

— Samantha Cristoforetti (@AstroSamantha) September 27, 2022

Heres how astronauts keep track of their weight while in space:

Can you 'weigh' yourself in weightlessness? Not with a regular scale. Take a look! #MissionMinerva #SpaceLife #SpaceTok @esa @esaspaceflight @Space_Station pic.twitter.com/iBuSnLsMlD

— Samantha Cristoforetti (@AstroSamantha) October 1, 2022

Oh, glamorous astronaut life!

Oh, glamorous astronaut life! Working in the bowels of our toilet, installing a new pre-treat tank. I do love space plumbing! No worries, the toilet wasnt broken, it was just a routine activity. Pre-treat is added to urine at every use for chemical stabilization. #MissionMinerva pic.twitter.com/NwYy7tetFg

— Samantha Cristoforetti (@AstroSamantha) October 4, 2022

Coral reefs as seen from space:

Coral reefs are an amazing sight from space, just as they are on Earth. They harbor a mindboggling diversity of marine life some call them the rainforests of the sea. Sad to think that we are on track to losing most of the worlds coral reefs to global warming.#MissionMinerva pic.twitter.com/2TUQ29Ks8q

— Samantha Cristoforetti (@AstroSamantha) October 7, 2022

Heres a fun video showing Cristoforetti replicating a scene from 2001: A Space Odyssey:

2022 A Space Odyssey. Turns out, yes, you can walk with Velcro shoes. Slowly, very very slowly #ASpaceOdyssey #MissionMinerva @esa @esaspaceflight @Space_Station pic.twitter.com/WI69RXmObE

— Samantha Cristoforetti (@AstroSamantha) October 8, 2022

Bacteria on the ISS could be harmful to human health. Heres how crewmembers test for it:

There are no harmful bacteria and fungi on the @Space_Station. And if there ever were any, we would find them Take a look! #MissionMinerva #SpaceLife #SpaceTok @esa @esaspaceflight @Space_Station pic.twitter.com/VmkZNEJegw

— Samantha Cristoforetti (@AstroSamantha) October 9, 2022

How microgravity means that having a cup of coffee in space is a little different to back on terra firma:

Having a nice cup of coffee looks slightly different in space Check it out! #MissionMinerva #CoffeeBreak #SpaceTok @esa @esaspaceflight @Space_Station pic.twitter.com/Z68rXcPZgx

— Samantha Cristoforetti (@AstroSamantha) October 12, 2022

Cristoforetti and her three fellow Crew-4 colleagues flying through the space station:

Its been an absolute pleasure to share this experience with my crewmates of Crew-4. What amazing human beings! #MissionMinerva @astro_kjell @astro_watkins @Astro_FarmerBob @NASA_Astronauts @esa @esaspaceflight @Space_Station pic.twitter.com/2RcRi7WY5n

— Samantha Cristoforetti (@AstroSamantha) October 13, 2022

And finally, a beautiful time-lapse video shot over Europe:

One last time, fly along with me! Farewell and, as always, thanks for all the fish! #MissionMinerva @esa @esaspaceflight @ESA_EO @Space_Station pic.twitter.com/Dpdushsdvu

— Samantha Cristoforetti (@AstroSamantha) October 13, 2022

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China’s Shenzhou 14 astronauts snap stunning photos of Earth, the moon and more – Space.com

Posted: at 10:58 am

China's Shenzhou 14 astronauts have been busy testing a new space station module, conducting spacewalks and carrying out experiments but they've also found time to take some spectacular photos.

China's human spaceflight agency, CMSA, released the photographs taken by the astronauts aboard the Tiangong space station during their ongoing mission, which launched June 3.

Images taken by Cmdr. Chen Dong show one of the station's flexible solar arrays against a backdrop of nighttime cities shining from Earth below, and another photo captures the airglow above our planet that results when sunlight interacts with atoms and molecules in Earth's atmosphere.

Related: China's Shenzhou 14 astronauts mark busy 1st month aboard Tiangong space station

Liu Yang, whose previous mission to space back in 2012 made her China's first woman in orbit, also snapped some pictures, including one of a full moon above Earth. Photos taken by Cai Xuzhe on his first trip to space include an image of Hainan island, just off the Chinese mainland, from where the Tiangong modules launched, and a tomato plant sprouting aboard the station.

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Shenzhou 14 is the third crewed mission to Tiangong. During the first, Shenzhou 12, astronauts also returned stunning images.

The Shenzhou 14 crew is scheduled to receive a new visitor later this month, when the third and final module for Tiangong is launched. The Mengtian module will complete the planned T-shaped orbital outpost.

The crewmembers are expected to stay in orbit until sometime in December, when they will welcome the incoming Shenzhou 15 mission astronauts and carry out China's first-ever crew handover.

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Tom Cruise Might Become the First Civilian to Spacewalk at the ISS – Smithsonian Magazine

Posted: at 10:58 am

European Space Agency (ESA) astronaut Matthias Maurer on a spacewalk outside theInternational Space Station Courtesy of NASA

Astronauts spend years undergoing rigorous training before they maketheir first trip into space. And before becoming astronauts, they usually already have years of experience in related fields, such as engineering, geology, aeronautics, physics, medicine and biology; many have doctorates or have seen military combat.

But for actor Tom Cruise, a trip to space might just be another day at the office. Cruise hopes to shoot scenes for an as-yet-untitled action film at the International Space Station (ISS) in the near future. If he succeeds, hed become the first civilian to do a spacewalk outside of the space station, according to Donna Langley, chairman of Universal Filmed Entertainment Group.

In a lengthy interview with the BBCs Katie Razzall, Langley reveals a few more details about the proposed movie, which is still an aspiration at this stage, per the BBC.

Tom Cruise is taking us to space, hes taking the world to space, Langley tells the BBC. Thats the plan. We have a great project in development with Tom.

Cruise and director Doug Liman, who worked together on the 2014 movie Edge of Tomorrow, pitched the idea for the new film to Langley on a Zoom call during the pandemic. Though she didnt share too many specific details about the plot, the general gist is that the storyline actually takes place on earth, and then the character needs to go up to space to save the day.

Cruise is already known for doing many of his own stunts, including some potentially dangerous ones, so it comes as no surprise that hes willing to take a rocket to the space station for the sake of cinema. As Daniel Kreps writes for Rolling Stone, its unclear whether Cruise would actually go inside the ISS or just walk around outside of the orbiting laboratory.

NASA, for its part, seems willing to collaborate on the movie. Though he has since deleted the tweet, former NASA administrator Jim Bridenstine wrote in May 2020 that the agency is looking forward to working with Cruise. We need popular media to inspire a new generation of engineers and scientists to make NASAs ambitious plans a reality, he wrote. Elon Musk, founder and CEO of SpaceX, which is working with NASA on a number of projects, replied that the project should be a lot of fun! As Deadlines Mike Fleming Jr. reported at the time, Musk, Cruise and NASA were all reportedly working together to make the film a reality.

Despite his lack of official astronaut training, Cruise does have some cinematic experience with space and aviation. In 2013, he played a futuristic drone technician who must defend Earth against alien invaders in Oblivion. He also narrated the 2002 Imax documentary Space Station 3D. One of his most popular air-and-space-related films, of course, is Top Gun, the 1986 flick about Navy fighter pilots. Cruise also recently starred in the sequel, Top Gun: Maverick.

Since the space stations launch nearly 24 years ago in 1998, ISS crewmembers have made just 253 spacewalksin other words, theyre not something NASA, the European Space Agency (ESA), Roscosmos or any of the other major space station partners take lightly. Spacewalks are inherently dangerous and, as such, NASA has a whole slew of rules and guidelines around them. As Paola Rosa-Aquino writes for Space.com, theyre also expensive and time-consumingwhenever possible, crewmembers try to use robotic arms to work outside the ISS.

Sometimes, though, astronauts (and Russian cosmonauts) have to go on spacewalks as a last resort. They typically have very specific reasons for leaving the space station, such as performing maintenance or installing new equipment. NASA calls these adventures extravehicular activities.

Wearing highly specialized suits outfitted with life support gear, crewmembers depart the space station through a special set of airlock doors. They remain attached to the space station via tethers, and they usually spend five to eight hours in space while completing their objectives.

Astronauts must complete special training before they undertake spacewalks. They spend a lot of time at NASAs Neutral Buoyancy Laboratory near the Johnson Space Center in Houston. There, theypractice spacewalks in a6.2-million-gallon poolin which they neither sink nor float. For every hour a crewmember will spend on an ISS spacewalk, they must spend seven hours in the pool, per NASA. They also train via virtual reality technologies that simulate extravehicular activities.

If Cruise ever does make it into orbit, there is another thing hell have to keep in mind: remembering to focus in the face of the vast cosmos. And thats not necessarily an easy feat, as NASA astronaut Mike Fincke told CNNs Ashley Strickland last year.

Its really truly breathtaking, he told the publication. The only thing between you and the rest of the universe, seeing the whole cosmos of creation, is the glass faceplate of your visor on your helmet, and its just awe-inspiring.

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SpaceX Crew-4 astronauts say their space station work will help get NASA to the moon – Space.com

Posted: at 10:58 am

NASA astronauts on the International Space Station are eyeing the moon, and what it would take to get there.

SpaceX's Crew-4 astronauts spoke from the orbiting lab about how their work is linking up with NASA's Artemis 1 moon mission, which could launch in November, and with other lunar sorties in the coming years.

"A really exciting part of what we're able to do up here [is] using the International Space Station [ISS] as a testbed for future exploration," NASA's Jessica Watkins told Space.com during a live press conference on Tuesday (Oct. 11), two days before Crew-4's scheduled return to Earth. (The SpaceX Dragon capsule carrying Watkins and her three crewmates is scheduled to splash down Thursday, Oct. 13, at 5:41 p.m. EDT, or 2141 GMT.)

Related: The Artemis plan: Why NASA sees the moon as a stepping stone to Mars

ISS research is gearing up for a big spaceflight leap: sending humans back to the moon for the first time since 1972.

Providing the uncrewed Artemis 1 mission to lunar orbit launches and lands as planned, NASA plans to send Artemis 2 around the moon with astronauts as soon as 2024. Following that, Artemis 3 is scheduled to land on the surface in 2025 or so. Watkins, a Black geologist, may be one of the people making the first lunar bootprints since Apollo 17, for NASA aims to land a woman and a person of color on Artemis 3.

A large chunk of space station research is devoted to human health, and to advancing technologies like life support or growing plants to make sure they are robust enough to take on the demanding lunar environment, Watkins explained.

"We are looking into ways to protect against some of the hazards that are associated with some of this exploration," Watkins said. Plants will need to contend with very different soil and weaker gravity, for example, while plants and machinery alike will need to deal with intense radiation at the moon's surface.

"Radiation is one of the biggest factors that needs to be mitigated as we move forward," Watkins added, which is why Artemis 1 will have so many sensors in the spacecraft to test and assess the environment.

Crew-5 members are testing out a radiation vest, AstroRad, that will also fly around the moon on an Artemis 1 mannequin. With the sun rapidly entering an active phase in its 11-year activity cycle, space radiation is reaching a high point around the solar system.

Putting AstroRad in Earth and lunar orbit at about the same time will allow scientists to compare ISS astronaut radiation exposure with the mannequin's to see how radiation is percolating across Earth's neighborhood and beyond, Watkins explained.

"The ISS is really enabling us to further technologies and understanding that will enable us to go further into the solar system," added Watkins, whose own research about Mars geology was published in a peer-reviewed journal shortly after she blasted into orbit. The topic: rocks studied by NASA's Curiosity rover.

Related: Amazing launch photos of SpaceX's Crew-4 astronaut mission

A typical space station crew looks at 200 or so investigations with the aim of banking reams of data for future crews to draw upon, no matter where they're located. Both Watkins and Crew-4 commander and fellow NASA astronaut Kjell Lindgren pointed to the human body's reactions to space as a key frame of their research.

One project on immune system science was "really looking at the aging process of immune cells, to better understand the immune dysfunction that we see in astronauts here on orbit," Lindgren said, adding that a shorter-term benefit will be creating better treatments for patients on Earth. "Truly understanding that at the cellular level that was a lot of fun to participate in."

Crew-4 crewmate Samantha Cristoforetti, who last visited the ISS nearly seven years ago, pointed to big changes in science since she last undocked: a scanning electron microscope, two 3D printers and "all kinds of facilities" to gather information for future crews, she said.

"There is a whole slew of life support technological technology demos that are running on space station, again, something new," said Cristoforetti, a European Space Agency astronaut. "It's an even busier space station."

Follow Elizabeth Howell on Twitter@howellspace (opens in new tab). Follow us on Twitter@Spacedotcom (opens in new tab)or Facebook.

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