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Category Archives: Transhuman News
Thirteen TUM researchers among the most cited worldwide – India Education Diary
Posted: November 29, 2020 at 5:34 am
Thirteen researchers from the Technical University of Munich (TUM) are among the most cited in their respective fields. This is shown by the current edition of the ranking Highly Cited Researchers.In their publications, scientists cite the most important papers previously published on the respective topic. The frequency of citations is therefore a good indicator of the quality and worldwide recognition of a research work and its authors. Using the Web of Science database, which records scientific publications from a wide range of disciplines, the US company Clarivate Analytics once a year identifies the Highly Cited Researchers.
The current edition of the ranking lists the scientists who were cited most frequently in their respective fields from 2009 to 2019. Researchers who were cited frequently in various fields are listed in the Cross-Field category. In total, the list includes about 6,400 persons in no particular order, including the following researchers from TUM:
Agricultural Sciences:
Chemistry:
Clinical Medicine:
Psychiatry and Psychology:
Environment and Ecology:
Cross-Field:
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Scientists successfully implanted human genes into monkeys to increase their brain mass – Boing Boing
Posted: at 5:34 am
From Popular Mechanics:
Researchers from Germany's Max Planck Institute of Molecular Cell Biology and Genetics in Germany and Japan's Central Institute for Experimental Animals introduced a specifically human gene,ARHGAP11B, into the fetus of a common marmoset monkey, causing the enlargement of its brain's neocortex. The scientistsreported their findings in Science.
Those findings include a good indication that the ARHGAP11B gene played a key role in the development of the human neocortex, and, by extension, human evolution overall. (A 2015 study saw similar results with ARHGAP11B implanted in mice embryos, which "produced many more neural progenitor cells and could even undergo folding of their normally unfolded neocortex.")
In a press alert, the scientists behind the study were careful to specifically refer to their subjects as "transgenic non-human primates," which differentiates them from transgenic common marmosets, or humans (we're not given a cool classification for the sake of objectivity). They also included this ethical caveat:
We confined our analyses to marmoset fetuses, because we anticipated that the expression of this human-specific gene would affect the neocortex development in the marmoset. In light of potential unforeseeable consequences with regard to postnatal brain function, we considered it a prerequisite and mandatory from an ethical point of view to first determine the effects of ARHGAP11B on the development of fetal marmoset neocortex.
So, we're still a little ways away from a horrible interactive Planet of the Apes remix. That's good.
Somewhat related: I re-read Karen Joy Fowler's award-winning fiction-about-science novel We Are All Completely Beside Ourselves this summer, which I think every human being should read if they have not yet.
Uh-Oh, Scientists Used Human Genes to Make Monkey Brains Bigger [Tim Childers / Popular Mechanics]
Human-specific ARHGAP11B increases size and folding of primate neocortex in the fetal marmoset [Michael Heide, Christiane Haffner, Ayako Murayama, Yoko Kurotaki, Haruka Shinohara, Hideyuki Okano, Erika Sasaki, and Wieland B. Huttner]
Human brain size gene triggers bigger brain in monkeys [EurekaAlert!]
Image: Public Domain via Wikimedia Commons
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This AI-enabled Mars exploration rover is as adorable as WALL-E! – Yanko Design
Posted: November 26, 2020 at 10:49 pm
Inhabitating a planet other than Earth is the next frontier for humankind, and were inching closer to that elusive dream, thanks to the rapid developments in science and technology. Already NASA has conducted unmanned missions on the Red Planet, and visionaries like Elon Musk already have their eyes set on colonizing Mars by 2050. This elusive dream has ignited the imagination of many who envision the future scenario, wherein, humans will rule the Red Planet.
This advanced rover christened Robonetica Explorer 1.0 is the culmination of the intuitive design thinkers AltSpace, Dmitry Lebedko, Dmitry Egorov, Oleg Butov, Yaroslav Goglev, Rashid Tagirov and Timur Mullya. The concept zeros-in on the importance of AI in the not so distant future. In fact, the Robonetica Explorer 1.0 is an AI and robotics platform envisioned by these young minds giving us a glimpse of what things could be like 4-5 decades in the future. Looking like an amalgam of the raw WALL-E robot and the sophisticated EVE (Extraterrestrial Vegetation Evaluator) the swift robot will scout the planets surface for explorations missions. It has a fully movable head with advanced cameras and sensors presumably to look for signs of life. To conquer the harshest of terrains, Robonetica Explorer 1.0 has six robust wheels mounted on individual suspensions.
The rover is a window into the future for sure and the team has designed it to be more like an interactive being than an autonomous robot. Perhaps, an advanced AI-enabled being that has feelings just like WALL-E!
Designer: AltSpace for Robonetica
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This AI-enabled Mars exploration rover is as adorable as WALL-E! - Yanko Design
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How long will it take to reach Mars? – SwordsToday.ie
Posted: at 10:49 pm
Elon Musk has a vision to carry one million people to Mars by 2050.
Although the CEO of SpaceX recently revealed that humans plan to live on the planets glass domes, many are still questioning how long it will take to get there, even if life on Mars is ideal?
There is a long distance between Earth and Mars, which means that any trip to the red planet will take a long time.
This is further complicated by the fact that the distances are constantly changing as the two planets revolve around the sun.
The closest distance between Earth and Mars is 33.9 million miles 9,800 times the distance between London and New York.
However this is very rare: the most useful distance is the average, i.e. 140 million miles.
Earth scientists have already launched a bunch of space probes to (or near) Mars, so we have a rough idea of how long it will take with current technology.
Historically, the voyage took 128 to 333 days a long time for humans to travel in a narrow spacecraft.
No man has ever set foot on Mars.
The Soviets first sent unmanned spacecraft to Mars in the 1960s.
NASAs Mariner 4 was the first successful space probe to orbit Mars.
This happened in 1965. In 1971, Soviet spacecraft landed on the surface of the Red Planet.
Since then, several spacecraft have been sent to explore Mars, but we will have to wait a little longer to send one person.
NASA has once again revealed its goal of sending one man to Mars by 2037.
Currently, no strong evidence of Mars past or present life has been found.
This does not mean that scientists are not looking.
There is evidence that the dry planet once had surface water and habitable conditions.
However, just because a planet has habitable conditions does not automatically mean that it has lived there or that there is life there.
Mars is the second most habitable planet in our solar system.
It is neither too hot nor too cold, and is thought to have enough gravity to adapt to the human body.
However, there is no free oxygen in the atmosphere, so humans cannot breathe if they do not receive oxygen on their own.
Humans also need to wear a pressure suit.
The soil is toxic, water is scarce, and you need protection from radiation and cold.
If any living thing on Earth wants to survive on Mars it must be in some kind of protective bubble.
Some scientists thought it could be more habitable because we could change the atmosphere of the planets.
We do not know exactly when humans will land on Mars.
NASA plans to place a man and the first woman on the moon in 2024.
After this mission, the Red Planet will be on the agenda, with current estimates that by 2030 we could see one man on Mars.
Elon Musk has previously stated that he wants to send a team of humans to Mars within the next decade.
Here is what you need to know about the red planet
Stunning footage of Tesla Roadster and Starman floating in space after the launch of the SpaceX Falcon heavy rocket
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Mars mission: Elon Musk says first settlers on Red Planet will live in glass domes – EconoTimes
Posted: at 10:48 pm
One of the goals when it comes to the upcoming Mars missions is to colonize the neighboring planet. SpaceX CEO Elon Musk recently stated that those who would become the first settlers on the red planet would have to live in glass domes.
Musk has already been planning for potential colonization of the neighboring planet as space agencies are already preparing for the upcoming Mars missions. Musk shared on Twitter that because of the lack of atmosphere on Mars, the first people who will settle there will be temporarily residing in glass domes. However, before the first settlers arrive on Mars, the red planet will have to be terraformed as soon as possible. Terraforming refers to transforming a planet to make its conditions similar to Earths which would make it habitable for humans.
Life in glass domes at first. Eventually, terraformed to support life, like Earth, tweeted Musk. Terraforming will be too slow to be relevant in our lifetime. However, we can establish a human base in our lifetime. At least a future spacefaring civilization -- discovering our ruins -- will be impressed humans got that far.
Musk previously shared that a way to terraform Mars is through the use of thermonuclear explosives in its polar regions. These regions are where the most carbon dioxide on the planet is stored. This would result in carbon dioxide getting released into the atmosphere to thicken it, and making the planet warm enough to sustain liquid water. However, the SpaceX CEO already warned of the dangers of being among the first people to set foot on Mars.
Musk previously stated that being able to make the trip to Mars, more so get to work on establishing a base on Mars is not for the faint of heart. Musk warned that the first travelers to Mars may die in the midst of an attempt to put up a base.
Meanwhile, NASAs Perseverance Rover is currently on its way to the Red Planet and will touch down on the Martian surface next year. But even as it is on its way at the moment, the agency has recorded the sounds of space as the Rover makes its way to Mars. The agency has since released the recordings of space sounds on its SoundCloud, where a faint humming noise could be heard.
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Japan Startup Aims to Colonize the Moon – AkihabaraNews
Posted: at 10:48 pm
Akihabara News (Japan) The Tokyo-based start-up ispace Inc. is taking further steps in an attempt to realize its vision of beginning the human colonization of the Moon within just a few years.
In its latest move, ispace opened this month a new office in Denver, Colorado, utilizing part of the approximately US$125 million that it has so far been able to raise in investment in its decade-long history.
The Japanese firm recently announced the appointment of Kyle Acierno as the CEO of its US branch and hired Kursten ONeill, who had seven years experience at SpaceX, as its US lander program director.
Upon the opening of the Denver office, ONeill stated, I truly believe exploring the Moon, Mars, and beyond is our destiny as a human race; the uniting factor to further our presence among the stars. By joining ispace to lead our US lander mission to the Moon, Im excited to bring together the best and brightest to innovate, create, and inspire an even larger shift in aerospace advancement and exploration.
Company founder and CEO Takeshi Hakamada added, We are very pleased to begin active operations in the United States, which is spearheading the global momentum toward lunar exploration. We believe we can provide value to the United States by complementing the deep US-Japan collaboration on lunar exploration as a commercial services provider operating in both countries.
ispace has opened its office in Denver mainly to more closely cooperate with its US partners, especially the National Aeronautics and Space Administration (NASA) and its Commercial Lunar Payload Services program.
That program aims to begin deliveries of cargo to the Moon, setting the stage for astronauts to start landing in 2024.
Currently, ispace is completing the lander design for its Mission 1 and expects to start assembling and testing it early next year.
Three years ago, ispace produced a video outlining its 2040 Vision of a Moon colony with a thousand inhabitants. It can be viewed below.
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Elon Musks Plans for Mars Are a Huge Waste of Money and Resources – Energy & Capital
Posted: at 10:48 pm
Elon Musk wants to send settlers to colonize Mars.
He said theyll ultimately have to terraform the planet, but first, theyll live in glass domes.
He also said he hoped to populate Mars with 1 million people in just 30 years.
Now, Ive never been one to trivialize big ideas. Particularly from Musk.
What hes done in terms of launching a transition away from the outdated internal combustion engine is truly amazing.
And his reusable rocket?
The implications of that technology will absolutely change the world.
But when it comes to Musks big plans for Mars, I have to call bullshit.
And also
As reported in The Independent, terraforming in this instance is a process that is believed would make Mars more habitable for human life:
This involves blasting the planet with nuclear weapons at its poles to cause the ice caps to melt and induce accelerated warming to make it comfortable for humans to live there.
Musk said, Eventually you can transform Mars into an Earth-like planet. Theres a fast way and a slow way. The fast way is to drop thermonuclear weapons over the poles.
He also suggested"a system of giant mirrors could be placed in orbit around Mars in order to reflect sunlight onto the surface."
No one has a price tag for any of this, by the way, but we do know that, according to Musk, it will cost $500,000 to send a single person to Mars.
And if Musk is trying to get 1 million humans to the red planet, youre looking at $500 billion.
And for what?
Why would we spend a half-trillion dollars to send people to Mars?
Well, according to Musk, we must colonize Mars to preserve our species after a third world war.
Seriously?
I dont know about you, but that seems like an awful lot of money to spend to preserve a species that put itself in this precarious situation to begin with.
Perhaps we should really ask ourselves if our species is even worth preserving at all...
And if it is, maybe we should table the Mars colonization thing for a bit while we figure out how to ensure our survival on this planet. Its not that we dont have the tools, intelligence, and resources to make that happen.
I imagine that with a half-trillion dollars to spend, we could make some pretty meaningful inroads into ensuring our survival for a very long time right here on Earth.
Certainly the ROI would be a lot higher.
Look, Im not trying to trivialize the value of Musks ability to make the impossible, well, possible.
What he did with Tesla and SpaceX is truly inspirational and has made a lot of people very, very rich.
But I would never invest in some fakakta plan to put a million people on Mars. Its stupid and a giant waste of money and resources.
What isnt stupid, however, is something Musk recently mentioned about a new energy technology that he says will be much bigger than anything hes accomplished with electric cars.
And thats a pretty bold statement to make when you consider Tesla is solely responsible for launching the electric car revolution.
Today, nearly every major automaker has dozens of new electric cars in development or on the roads. And that all started after Musk showed that electric cars didnt have to be glorified golf carts and, of course, people would buy them.
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But this new technology hes talking about has nothing to do with electric cars. In fact, Musk said this technology will not only dwarf what weve seen with the electric car, but the market will grow much, much faster.
So what is it?
And why is he so bullish on it?
Well, it is pretty incredible.
Its a new energy technology that can power the 90 million-plus buildings and homes in the U.S. alone and do it more cheaply than any fossil fuel or other renewable energy technology currently on the market.
So cheap, in fact, it can do it for virtually nothing 24 hours a day, seven days a week.
Apple already has $3 billion invested in a version of this technology, and Facebook is ponying up $416 million.
Bottom line: Unless you hate money, you need to learn everything you can about this technology now, and that includes the name of the company producing it and, of course, its stock symbol.
You can get access to all this information in this recent investor note.
Theres also a special report that outlines this technology, who invented it, and how much its worth. That report can be downloaded here.
I know its Thanksgiving, and not a lot of folks are thinking about investing right now.
But I am.
And given the potential of this new technology that Elon Musk is salivating over, Id be a fool not to.
Click here to learn more.
To a new way of life and a new generation of wealth...
Jeff Siegel
@JeffSiegel on Twitter
Jeff is the founder and managing editor of Green Chip Stocks, a private investment community that capitalizes on opportunities in alternative energy, organic food markets, legal cannabis, and socially responsible investing. He has been a featured guest on Fox, CNBC, and Bloomberg Asia, and is the author of the best-selling book, Investing in Renewable Energy: Making Money on Green Chip Stocks. For more on Jeff, go to his editor's page.
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The Interplanetary Transport Platform and Space Travel Community Network – Your Digital Wall
Posted: at 10:48 pm
(YourDigitalWall Editorial):- San Francisco, Oct 22, 2020 (Issuewire.com)Interplanetary Transport, the main information platform, network portal, and project organization was started in 2015 and founded in 2016 by Oliver Gediminas Caplikas. The official pages were registered by the founder and are saved by international rights. Most of the projects and websites are in work and will be published if they are ready so far, even if it needs some years more, especially in these times. Interplanetary Internet and international partners will support various project developments. Joint ventures, long-term cooperations, collaborations, or other sustainable partnerships are welcome. New investors and sponsors are invited to join the outstanding projects. You can get more details on the official pages and request information by the official channels.
With the right support, the main project development of the communication portal and information platform will not just inform about interesting developments for upcoming space developments and innovations for Earth, Moon, Mars, and space. Together we can work on awesome developments and projects like moon drones, space drones, space debris clean up solutions, better interplanetary internet services, and much more of awesome space stuff. Help us to reach new frontiers and horizons, for a better future on Earth and in space. Interplanetary Transport project developments like the Cargo Spacecraft project working on recyclable and reusable transport systems. Old parts of cargo ships, satellites and space crafts can be used to build big cargo ships in space. Innovative foldable containers, thin solar panels and solar foils will provide enough energy. Sustainable propulsion technologies with an alternative or renewable fuels will power the autonomous transport ships between space stations, moons and planets like Mars. Much of the materials and fuels can be mined on asteroids and the moons in future.
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For advanced space exploration and space colonization or space settlement, we need a special space station and base camp for the Moon. For advanced space travels and interplanetary transport logistics, we need a moon and mars station, a kind of hub or gateway in the orbits. Humanity and especially the space industry should rethink their space programs towards more reusable and sustainable space developments. There are much good cleantech and Greentech developments on Earth that can be used for space, lunar, and Mars missions. Many old satellites could be reactivated and upgraded as carriers for new technologies, even as simple communication node they would be useful. It is really time for startups who work on satellite or spacecraft recycling and upcycling solutions.
Another great idea is to use old space stations for future space exploration. The next generations will thank us and they will have a kind of live museum of the human history of space travel. The International Space Station can be sent into higher Earth orbit and later after the official lifespan in moon or Mars orbit or even into deep space! The station can be used as an autonomous science lab, similar to satellites with sensors and scientific equipment. It is a chance to use the ISS as an unmanned space system, network node/server, and science platform with a lot of new sensors to study our solar system. Change from wasting resources to a sustainable space economy, industry and space society. Start to clean up and recycle the space debris, use lasers, and other innovative tools for small parts. Collect bigger parts of space junk with special satellites or cargo spaceships.
Newest developments and projects are Cargo Spacecraft, Galactic Internet, Interplanetary Europe, Lunar Base Camp, Moon Base Station, Moon Drone, Moon Station EU, Solar System Internet Hub,.. tbc.
Check also the project Greening Mars. All kinds of cleantech, greening, GreenTech, and sustainable space projects or innovative ideas are welcome. Think about green spots or oases on moons and desert planets like Mars, no problem with greening space stations and greenhouse spaceships. But we need to care about our planet first! If the Earth becomes a desert planet we dont need to travel or colonize Mars. Even space exploration or space travel makes no sense with such problems on Earth which should be solved primarily. We need to reduce deforestation, desertification and global warming on planet Earth before it is too late. Each day humans destroying so many species on Earth, some of them are even unknown. The mass extinction goes on, the space programs should care more about. Lets discuss such important issues and topics. You are welcome to join the Interplanetary Internet and Interplanetary Transport network groups on Facebook and Linkedin. The founder focusing since 2017 on the climate crisis and climate change problems. Thats why he started new projects and initiatives like the Greening Deserts Greening Camps and the Trillion Trees Initiative to reduce the human-made deforestation, desertification and global warming. The projects have big potential to improve the air quality, biodiversity, soil and water quality worldwide. Humanity needs healthy environments and functioning ecosystems to expand or to be really productive. We need a healthy planet Earth for future generations and developments. Without that there wont be a real future for humanity on Earth and in space. Constructive feedback, useful advises and real support is always welcome.
Interesting space quotes:
As we begin to comprehend that the earth itself is a kind of manned spaceship hurtling through the infinity of space it will seem increasingly absurd that we have not better organized the life of the human family. Hubert H. Humphrey
Human exploration and colonization of Mars will keep us busy for hundreds, even thousands, of years. During that time, there will be advances in nanotechnology, space sailing, robotics, biomolecular engineering, and artificial intelligence. These advances are occurring even now, affecting our outlook about what it means to be human and engage in human activity. Those technologies will not merely allow us to stay home on Earth and Mars, but our minds will extend our presence throughout the universe so that we will not need or want to extend our bodies there even if we could, which I think is doubtful. Louis Friedman
I look up at the night sky, and I know that, yes, we are part of this Universe, we are in this Universe, but perhaps more important than both of those facts is that the Universe is in us. When I reflect on that fact, I look up many people feel small because theyre small and the Universe is big, but I feel big because my atoms came from those stars. Neil deGrasse Tyson
In space, race doesnt matter, nationality doesnt matter. In space, you see the world as a globe and you dont see the boundaries. Maggie Aderin-Pocock
The exploration of space will go ahead, whether we join in it or not, and it is one of the great adventures of all time, and no nation which expects to be the leader of other nations can expect to stay behind in the race for space. John F. Kennedy
Space is for everybody. Its not just for a few people in science or math, or for a select group of astronauts. Thats our new frontier out there, and its everybodys business to know about space. Christa McAuliffe
Space tourism will bloom very soon Regular tourist flights, orbital hotelsthen the real payoff begins. I foresee an interplanetary cruise ship, a lunar cycler. Assembled in Earth orbit, this liner is given a powerful pushsending it on its way to the moon. The lunar cycler will undergo a cosmic dance: loop around the moon, return to Earth, slingshot around Earth, and return to the moon again. The round-trip will take just over a week. And every time the lunar cycler swings by Earth, itll be met by a supply ferry, maybe even restocked with champagne, and boarded by a fresh group of travelers. Buzz Aldrin
Welcome to the future of humanity. A society of developers, explorers, pioneers, and real humane humans. The case we survive the climate crisis. We need to reduce deforestation, desertification, and global warming on planet Earth before it is too late. If the Earth becomes a desert planet we dont need to travel or colonize Mars. Even space travel makes no sense with such problems on Earth which should be solved primarily. Why humanity is wasting so much money and resources for space exploration who does not help to reduce the climate crisis? Why explore space for a single new life form like bacteria or unicellular organisms? Each day humans destroying so many species on Earth, some of them are even unknown. This is really senseless and paradoxical. The mass extinction goes on, the space programs should really care more about. Oliver G. Caplikas
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The Interplanetary Transport Platform and Space Travel Community Network - Your Digital Wall
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Gaucher Disease Treatment Market Booming in Americas & Europe With Top Players, Growth, Size, Major Drivers and Forecast to 2026 | Genzyme…
Posted: November 24, 2020 at 8:56 pm
The Global Gaucher Disease Treatment Market report provides a holistic evaluation of the market for the forecast period (20182026). The report comprises of various segments as well an analysis of the trends and factors that are playing a substantial role in the market. These factors; the market dynamics involve the drivers, restraints, opportunities and challenges through which the impact of these factors in the market are outlined. The drivers and restraints are intrinsic factors whereas opportunities and challenges are extrinsic factors of the market. The Global Gaucher Disease Treatment Market study provides an outlook on the development of the market in terms of revenue throughout the prognosis period. Major Players included in this report are as follows Genzyme Corporation, Pfizer, Inc., Shire Human Genetics Therapies, Inc., and Actelion Pharmaceuticals Ltd. (acquired by Johnson & Johnson in June 2017). There are various drugs in pipeline of companies such as Lixte Biotechnology Holdings Inc, JCR Pharmaceuticals Co Ltd, Pharming Group NV and Orphazyme ApS, for Gaucher disease treatment.
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Global Gaucher Disease Treatment Market: Scope of the Report
This report provides an all-inclusive environment of the analysis for the Global Gaucher Disease Treatment Market. The market estimates provided in the report are the result of in-depth secondary research, primary interviews and in-house expert reviews. These market estimates have been considered by studying the impact of various social, political and economic factors along with the current market dynamics affecting the Global Gaucher Disease Treatment Market growth.
Global Gaucher Disease Treatment Market: Competitive Landscape
The market analysis entails a section solely dedicated for major players in the Global Gaucher Disease Treatment Market wherein our analysts provide an insight to the financial statements of all the major players along with its key developments product benchmarking and SWOT analysis. The company profile section also includes a business overview and financial information. The companies that are provided in this section can be customized according to the clients requirements.
Geographically, this report studies the top producers and consumers in these key regions
Important details covered in the report:
Data regarding the information related to the production covering these economies is provided. The report reveals information regarding each region along with the production growth in the report. Crucial details relatable to the growth rate accounted for every region in the Gaucher Disease Treatment market is revealed in the report. The study also mentions information regarding the import and export patterns, the consumption rate as well as consumption volume in the report.
Global Gaucher Disease Treatment Market: Research Methodology
The research methodology is a combination of primary research secondary research and expert panel reviews. Secondary research includes sources such as press releases company annual reports and research papers related to the industry. Other sources include industry magazines, trade journals, government websites and associations were can also be reviewed for gathering precise data on opportunities for business expansions in Global Gaucher Disease Treatment Market.
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Introduction about Global Gaucher Disease Treatment Market
Global Gaucher Disease Treatment Market Size (Sales) Market Share in 2018 by Product Type (Categorization) Global Gaucher Disease Treatment Market Size (Sales) Market Share in 2018 by Application Type (End-Users) Global Gaucher Disease Treatment Growth Rate and Sales (2018-2026) Global Gaucher Disease Treatment Market Share and Sales (Volume) Comparison by Applications Global Gaucher Disease Treatment Suppliers/Players Profiles along with their Sales Data Gaucher Disease Treatment Competition by Region, Application, Type, and Suppliers/Players Defined (Value, Sales Price, and Volume) table for each geographic region under Gaucher Disease Treatment A separate table of product value, market sales, gross margin, and revenue (2014-2019) for each product type
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Major Topics Covered in this Report
Chapter 1 Study CoverageChapter 2 Executive SummaryChapter 3 Market Size by ManufacturersChapter 4 Production by RegionsChapter 5 Consumption by RegionsChapter 6 Market Size by TypeChapter 7 Market Size by ApplicationChapter 8 Manufacturers ProfilesChapter 9 Production ForecastsChapter 10 Consumption ForecastChapter 11 Upstream, Industry Chain and Downstream Customers AnalysisChapter 12 Opportunities & Challenges, Threat and Affecting FactorsChapter 13 Key FindingsChapter 14 Appendix
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Gaucher Disease Treatment Market Booming in Americas & Europe With Top Players, Growth, Size, Major Drivers and Forecast to 2026 | Genzyme...
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Prevail Therapeutics Granted Composition of Matter Patent for Experimental Gene Therapy Program PR001 – GlobeNewswire
Posted: at 8:56 pm
NEW YORK, Nov. 18, 2020 (GLOBE NEWSWIRE) -- Prevail Therapeutics Inc. (Nasdaq: PRVL), a biotechnology company developing potentially disease-modifying AAV-based gene therapies for patients with neurodegenerative diseases, today announced that the United States Patent and Trademark Office (USPTO) onNovember 17, 2020issued a composition of matter patent, U.S. Patent No. 10,837,028,with claims directed to the AAV vector used in PR001, Prevails experimental gene therapy program for the treatment of Parkinsons disease with GBA1 mutations (PD-GBA) and neuronopathic Gaucher disease (nGD). The base patent term extends until October 3, 2038, excluding patent term extensions or coverage in additional related patent filings.
We are excited to make important progress this year with PR001, which is being evaluated in the Phase 1/2 PROPEL trial for patients with Parkinsons disease with GBA1 mutations and in the Phase 1/2 PROVIDE trial for patients with Type 2 Gaucher disease, said Asa Abeliovich, M.D., Ph.D., Founder and Chief Executive Officer of Prevail. We are advancing clinical development of PR001 to make a potentially transformative difference for these patients who currently have no approved treatment options.
The Company recently announced that patient dosing has continued in the Phase 1/2 PROPEL clinical trial of PR001 for PD-GBA patients, and it expects to provide the next biomarker and safety analysis on a subset of patients in the PROPEL trial by mid-2021. The Company expects to initiate enrollment of the Phase 1/2 PROVIDE clinical trial of PR001 for Type 2 Gaucher disease patients in the fourth quarter of 2020 and currently anticipates it will provide the next update on PR001 biomarker and safety data for nGD in 2021.
The U.S. Food and Drug Administration has granted Fast Track designations for PR001 for the treatment of PD-GBA and nGD. In addition, the FDA granted PR001 Rare Pediatric Diseasedesignation for the treatment of nGD, and Orphan Drugdesignation for the treatment of patients with Gaucher disease.
About Prevail TherapeuticsPrevail is a gene therapy company leveraging breakthroughs in human genetics with the goal of developing and commercializing disease-modifying AAV-based gene therapies for patients with neurodegenerative diseases. The Company is developing PR001 for patients with Parkinsons disease with GBA1mutations (PD-GBA) and neuronopathic Gaucher disease (nGD); PR006 for patients with frontotemporal dementia withGRNmutations (FTD-GRN); and PR004 for patients with certain synucleinopathies.
Prevail was founded by Dr.Asa Abeliovichin 2017, through a collaborative effort withThe Silverstein Foundationfor Parkinsons with GBA and OrbiMed, and is headquartered inNewYork, NY.
Forward-Looking Statements Related to PrevailStatements contained in this press release regarding matters that are not historical facts are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended. Examples of these forward-looking statements include statements concerning the potential for Prevails gene therapy candidates to make a transformative difference for patients with neurodegenerative diseases; the expected timing of reporting additional interim data on a subset of patients from the PROPEL trial; and the anticipated timing of enrollment of and the next update on data from the PROVIDE trial. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. These risks and uncertainties include, among others: Prevails novel approach to gene therapy makes it difficult to predict the time, cost and potential success of product candidate development or regulatory approval; Prevails gene therapy programs may not meet safety and efficacy levels needed to support ongoing clinical development or regulatory approval; the regulatory landscape for gene therapy is rigorous, complex, uncertain and subject to change; the fact that gene therapies are novel, complex and difficult to manufacture; and risks relating to the impact on our business of the COVID-19 pandemic or similar public health crises. These and other risks are described more fully in Prevails filings with the Securities and Exchange Commission (SEC), including the Risk Factors sections of the Companys most recent Annual Report on Form 10-K and Quarterly Report on Form 10-Q filed with the SEC, and its other documents subsequently filed with or furnished to the SEC. All forward-looking statements contained in this press release speak only as of the date on which they were made. Except to the extent required by law, Prevail undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made.
Media Contact:Lisa QuTen Bridge Communications LQu@tenbridgecommunications.com678-662-9166
Investor Contact:investors@prevailtherapeutics.com
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Prevail Therapeutics Granted Composition of Matter Patent for Experimental Gene Therapy Program PR001 - GlobeNewswire
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