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Two of late night televisions best will share the spotlight tonight on an all-newReal Time with Bill Maher. Jimmy Kimmel is set to be Bill Mahers featured guest.

Kimmel and Maher will have plenty to talk about on tonights show. Both are trying to figure how to do a late night comedy show in these times, both have been targets of former President Donald Trump, and both have set their comedic sights on Republicans like Representative Marjorie Taylor Greene.

Anytime there is a crossover event among late night television hosts, fans get excited. Combinations like Seth Meyers and Jimmy Fallon or Stephen Colbert and Conan OBrien have resulted in some memorable moments.

OnReal Time, Kimmel will be even more free to speak his mind than when hes on ABC. Any uncertainty about how he feels about the news should be put to rest tonight.

Real Time with Bill Maheris currently at the start of season 19 on HBO. Maher jumped headfirst into the discussion surrounding the Capitol insurrection and former President Donald Trumps impeachment.

Meanwhile,Jimmy Kimmel Live!recently celebrated its 18th year on ABC. The show has become increasingly political in the past five years and it has paid off.

It was actually Jimmy Kimmel whom ABC tapped to fill the late night slot left behind when Bill MahersPolitically Incorrectwas canceled.

Kimmel has made one previous appearance onReal Time with Bill Maher. It came in April of 2003, just a few months afterJimmy Kimmel Live!premiered on ABC.

It all worked out for both comedians as Maher has thrived on HBO and Kimmel currently sits in second place behindThe Late Show with Stephen Colbertin the late night ratings. Now the two are back together for what should be an entertaining conversation.

Real Time with Bill Maherairs tonight at 10:00 P.M. The other guests are journalist and author Charlotte Alter and author, pundit, and podcast host Matt Welch.You can watch on HBO or on HBO Max. Be sure to check back with Last Night On for all the highlights.

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Bill Maher welcomes another late night host to Real Time tonight - Last Night On

Jimmy Kimmel and Bill Maher had a wide-ranging, late-night comedy love-in to kick off tonights episode of Real Time, with the guest comparing the host to starting Super Bowl quarterback Tom Brady.

Sundays Super Bowl LV pits Bradys Tampa Bay Buccaneers against quarterback Patrick Mahomes defending champion Kansas City Chiefs. Maher groaned, If I have to listen to sportscasters or anyone else on TV sucking Tom Bradys dk Hearing the hype, Maher said he has been praying, Please, Mahomes, beat this motherfker!

The host of ABCs Jimmy Kimmel Live conceded that even though Brady has certainly won his share of everything, he is nevertheless rooting for Brady on Sunday for a reason that he said is universal. This is a guy who was told by his employer he said, preparing to describe Bradys departure from the New England Patriots, before a thought occurred to him. By the way, this reminds me a little bit of you, he told Maher. When you were at ABC, they said, Alright, thats it were done. You went on to become tremendously successful here at HBO. Youre like the Tom Brady. I think you want the accolades for yourself! In other words, he seemed to suggest, Maher is in some way jealous of Brady for possibly pulling off a revenge act that would outdo Mahers rebound from being bounced from ABCs Politically Incorrect.

Everybody whos been fired from a job goes, Ugh, Id love to see this guy leave this job,' Kimmel reasoned. They go in the toilet, he goes to Tampa which is also a toilet, lets be honest. I lived there, I know. And then hes in the Super Bowl again and, who knows, he might win it.

The pair covered a few other topics during the chatty segment, including Mahers 10-year investment in the New York Mets baseball team which Maher said reached its end during the near-death experience of 2020. Even though he was constantly writing checks during a period when the team was unable to play, he still made out like a fking bandit on his original outlay.

Noting how many people seem to be wanting to leave California (a pet topic of Mahers), the host asked Kimmel to describe a recent road trip he took to Idaho in an RV with his family. He admitted that after sweating it out in a hot tent Did you know tents dont have air conditoning? Kimmel asked. Tents?! Maher replied the family packed up and drove to Caesars Palace in Las Vegas. They have parking for RVs there! Kimmel added. Of course they do, Maher said, after admitting he pines for his tour dates in Vegas lost to Covid-19.

Speaking of the pandemic, the two also compared notes on having to perform to an audience consisting only of their own writing staffs due to health and safety restrictions. Kimmel joked that his writers are sick of listening to him. We should switch staffs! he proposed. It will be like swinging, he explained, but for talk shows.

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Jimmy Kimmel Compares Bill Maher To Tom Brady, Admitting He Is Pulling For The Super Bowl Quarterback - Deadline

Expert: Hate group 'Proud Boys' part of Trump base AP Domestic

The Canadian government addedthe Proud Boys,an extremist group with ties to white nationalism, to its list of terrorist organizations.

Public Safety Minister Bill Blair announced Wednesday the Proud Boys were one of 13 groups now designated as terrorist organizations, includingthe Russian Imperial Movementand two neo-Nazi groups the Atomwaffen Division and The Base.

Canada will not tolerate ideological, religious or politically motivated acts of violence, Blair said.

Canada is the first country to designate the Proud Boysas a terrorist entity.

Designating a groupa terrorist organization allows the government to seize its assets and increase terrorism-related penalties.

A government official said just because a person is a member of the organization doesnt mean they will automatically be charged with a crime. But if that personwas to engage in violent acts, they could face terrorism charges.

Sending money to the organization or buying Proud Boys paraphernalia would also be a crime.

The announcement comes a little more than a week after Canada'sHouse of Commons unanimously passed a motioncalling for the government to use all available tools to address the proliferation of white supremacists and hate groupsstarting with the immediately designating the Proud Boys as a terrorist entity," Global News reported.

The motion was introduced by the leader of the country's New Democratic Party, Jagmeet Singh, who urged Canadians to "keep the pressure on" Prime Minister Justin Trudeau and the federal government to formally add the group to the list of terrorist organizations, which includes Boko Haram, the Taliban and al-Qaida.

Singh celebrated the announcement, calling it a victory for young people, working people and Black, brown and Indigenous people on Twitter.

The Proud Boyswere founded in 2016 byVice Media co-founder Gavin McInnes, a Canadian, anddescribed themselves at the time as a politically incorrect mens club for Western chauvinists."

Who are the Proud Boys?Far-right group has concerned experts for years

McInnes quit the Proud Boys after an October2018clashbetween group members and antifa that followedhis speech at New Yorks Metropolitan Republican Club.

The group is known for its"anti-Muslimand misogynistic rhetoric," according toThe Southern Poverty Law Center, a legaladvocacy organizationthat has designated the Proud Boys as a hate group. The SPLC has been warning about the group's violent tendencies for years.

The Canadian government calls the Proud Boys a neo-fascist organization with semiautonomous chapters located in Canada, the United States and other countries. It said the groupengages in political violence and that members espouse misogynistic, Islamophobic, anti-Semitic, anti-immigrantand white supremacist ideologies.

The group has faced renewed criticismafter several members were arrested for participating in the deadly riot at the U.S. Capitol building in support of former President Donald Trump.A Canadian government senior official said the Jan. 6 insurrection at the U.S. Capitol contributed to the designation.

More: Proud Boys organizer Joseph Biggs charged in deadly Capitol riot

Enrique Tarrio, the group's current leader,was arrestedlast month in Washington, D.C., and charged with destruction of property in connection with a Decemberincidentwhere set fire toaBlack Lives Matter banner after a Trump rally. The banner had been taken from a historic Black church.

Contributing: Joel Shannon and Will Carless, USA TODAY; The Associated Press

Follow N'dea Yancey-Bragg on Twitter: @NdeaYanceyBragg

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Canada becomes first nation to declare the Proud Boys a terrorist organization - USA TODAY

publication date: Feb. 5, 2021

By Hagop M. Kantarjian, MD

Professor and chairman, Department of Leukemia,

Samsung Distinguished University Chair in Cancer Medicine,

MD Anderson Cancer Center

Humans cannot live without hope. Hopelessness is the greatest trauma a person has to suffer.Emil J Freireich, MD

Dr. Emil J Freireich gave me hopejust as he did for millions of patients, loved ones, physicians and researchers. He brought me from Lebanon to the United States and provided me with endless opportunities to develop as a leukemia researcher and as a human being.

Not only was he my mentor, I considered him my third parent. After losing both my parents, in 2000 and 2001my mother being the most intelligent person I have ever known and my father being the hardest-working person I have ever metI realized that the people I loved most outside my immediate family were those in my professional one.

Foremost among them was Freireich.

When I started my career as a medical student at the American University of Beirut in 1972, I had decided I wanted to cure cancer (like millions of others). I told my father, but he said, There is no such specialty. Dont waste your time.

This was somewhat true considering that the field of cancer research and care was in its infancy. When Freireich joined the National Institutes of Health in 1955, he was among the first generation of cancer doctors, perhaps a dozen, that included Gordon Zubrod, James Holland, Emil Frei, and otherstodays pioneering giants in cancer.

He was the inaugural leukemia expert, and soon enough demonstrated that leukemia was the first cancer that could be cured with drugs. Before him, M.C. Li had shown that choriocarcinomas could be cured with methotrexate (1955), but a common belief then was that this was a tumor of the fetus, thus foreign or allogeneic, but that syngeneic tumors were incurable. But I digress

Despite my fathers objections, I was reading the 1970s literature, and the name of Freireich and his colleagues from MD Anderson came up over and over in many of the innovative cancer discoveries and papers: Gerald Bodey, Edmond Gehan, Michael Keating, Kenneth McCredie, Evan Hersh, Jordan Gutterman (the list goes on and on).

Memorial Sloan Kettering was then the only other fully dedicated cancer research center. So, in 1978, as a fourth-year medical student, I applied to both Memorial Sloan Kettering and MD Anderson for a four-month elective rotation.

Memorial rejected me immediately. Freireichwho led the Developmental Therapeutics department at MD Andersonaccepted me immediately, sans voir (as they say in poker). I thought it was because I was so great, but I realized later that Freireichs motto was similar to a line in Georges Brassenss poetry: Embrasse-les tous, Dieu reconnaitra le sien (Embrace them all, God will sort his own).

He accepted us all, the geniuses and the less so, the hardest working and the lesser ones, and molded us over time into the best cancer researchers we could be. And perhaps because of Freireichs massive magnetic personality, his dashing expansive charisma, his unlimited innovative capacities, his larger-than-life figure, and his infinite optimism, he attracted a certain breed of physicians, students, cancer researchers and followers destined to remain in cancer research and transformed them into the cancer researchers he wanted them to become.

And he attracted then from the four corners of the world. Fernando Cabanillas tells this story:

When Freireich welcomed the new fellows in July 1974, in his welcome speech he said that all of us in the room had been selected because we were geniuses. I was so naive that I believed him. I did not consider myself a genius, and was even worried that I had been accepted at MD Anderson through a bureaucratic error, and that I would eventually be discovered. Nevertheless, I started believing him, and he made us all feel important and capable of anything, which I obviously think was what he wanted.

When Freireich came with Frei to MD Anderson in 1965, the institution was barely on the map. Freireich was tasked with starting a cancer research program for developmental therapeutics, or DT.

Ten years later, DT became the largest cancer research program in the world, with more than 100 experts drawn from over 60 countries: New Zealand (Kenneth McCredie), Australia (Michael Keating,Andrew Burgess, Gary Spitzer, John Seymour), Japan (Ryuzo Ohno), Sweden (Borje Andersson),Czechoslovakia (Miloslav Beran), Germany (Bart Barlogie and Axel Zander), Hungary via Colombia (Gabriel Hortobagyi), Canada (Razelle Kurzrock), Holland (Karl Dickie, Lejda Vellekoop), India (Sewa Legha, Sunda Jagannath, Varsha Gandhi), Israel (Giora Mavligit, Moshe Talpaz, Zeev Estrov, Meir Wetzler), Lebanon (Elias Anaissie, Issam Raad, Fadlo Khuri,Philip Salem), Mexico (Jorge Quesada, Jorge Cortes), Panama (Adan Rios), Puerto Rico (Fernando Cabanillas), Peru (Manuel Valdivieso, Carlos Vallejos, who later became minister of health in Peru), and on and on.

There were even Americans: Gerald Bodey, Edmond Gehan, Evan Hersh, William Plunkett, Walter Hittleman, Susan OBrien, Jeane Hester, Jordan Gutterman, Robert Benjamin, Elihu Estey, etc

The 1974-75 fellowship class included the four bearded ones: Keating, Hortobagyi, Cabanillas, Barlogie. Each became one of the most prominent cancer researchers in his field (leukemia, breast, lymphoma, myeloma, respectively). The Department of Developmental Therapeutics was not only the largest, but also the most diverse in the world, akin to the Tower of Babel.

Before meeting Freireich, I was very much a person who followed established medical traditions and textbooks. I accepted medical standards and norms without questioning and believed everything that was in the booksunchallenged. At the American University of Beirut as in many other places in the world, knowledge is acquired by absorption of existing facts and information.

Freireich emphasized that all knowledge is contemporary and transient, that medical knowledge doubles every two years, and that 90% of what we hold as true in cancer research and care will be obsolete in 10 years. He taught me to think outside of the box, to always challenge concepts of leukemia care and research.

When I first arrived at MD Anderson in 1978, I started going to the DT meetings, attended by over 40-50 of the then best known cancer researchers in the world, the ones whose work and research I was reading in numerous publications (Bodey, Hersh, Gutterman, Benjamin, Hortobagyi, Keating, McCredie, Barlogie, Cabanillas, Legha, etc.).

I was still a 24-year-old who accepted established authorities, but I realized that this was Texas, the Wild West, a true Babel of cacophonies and opposing views espoused by brilliant researchers with big egos, brought together to advance the cancer cause.

Meetings would get tense, as many opinions were shared, sometimes even shouted. I would leave that dangerous environment four months later to return home to the safety of the civil war in Lebanon.

But I was already infected by the Freireich bug and returned to MD Anderson in 1981 to join his fellowship program. In 1983, I became an associate faculty member in the Leukemia Department and spent the next three to four years rounding with Freireich, McCredie, Keating and Estey almost every other month.

Each was a great teacher, and all had a great sense of humor. For me, these were the happiest, most fun memories. Freireich was a great raconteur, and I learned much through his humor.

Freireich, Michael Keating, and Hagop Kantarjian at a 1985 meeting in Sicily Source: Hagop Kantarjian

The so called Freireichs Laws were often funny, and he delivered them, as he did many of his conversations, with the perfect pitch and timing of a great comedian, while they still carried an unparalleled depth of wisdom and knowledge.

Discussing a famous statement attributed to Hippocrates, First do no harm, Freireich pointed out in his Karnofsky lecture that Primum non nocere fails to do the possible and the necessary (Law number 5; physicians creed).

Certainly, any lay person is qualified to do no harm. The physicians admonition must clearly bedo what can possibly be done and, perhaps more important, do that which is necessary.

Law number 1 (clinical investigators creed): The primary beneficiary of clinical research is the patient participating in that research.

Law number 2 (optimists creed): Always be prepared for success. Failure creates problems.

Law number 7 (regulators creed): The general solution to a specific problem will soon become a specific problem requiring a general solution.

Law number 17: Dont let toxicity interfere with success. Figure out a way to avoid it The worst toxicity is progressive cancer.

Another unnumbered law: Any research not worth doing is not worth doing well.

Freireichs laws in the treatment of sarcomas

Clinical Investigators Creed: The primary beneficiary of clinical research is the patient participating in that research.

Optimists Creed: Always be prepared for success. Failure creates problems.

The Academic Question: If we must experiment on patients to obtain medical information, then we had best do without that information.

Statisticians Creed: The best therapeutic research gives the best results.

Physicians Creed: Primum Non Nocere fails to do the possible and the necessary.

Health Service Delivery Creed: The best care (service) is clinical research. Alternate form: the best clinical research offers the patient the best possible care.

Freireich loomed over our lives. On our best days, we could only wish to be what Freireich was on any one of his average days.

Still, because of his dominating personality, strong opinions and unfiltered counsel, the world of Freireich was divided into two kinds of people: Those who loved him unconditionally and those who resented him unconditionally. Yet, even in their resentment, they admired him, respected him and continued to follow his research.

Still, because of the clashes with the cancer establishment, he never received his full due. He was the first leukemia researcher ever and the first to cure leukemia, yet he never received any of the American Society of Hematology awards. He was never awarded the Nobel Prize in Medicine, but then, greatness is not measured in awards.

Georges Brassens and Jacques Brel, the two greatest French poets ever, and Van Morrison were never awarded the Nobel in literature (although Bob Dylan finally was). And neither were Philip Roth or Salman Rushdie (yet).

But as controversial as Freireich was in leukemia and cancer, he was extremely respectful of the opinions of individuals he loved.

Freireich, Michael Keating, and Hagop Kantarjian at a 1985 meeting in Sicily Source: Hagop Kantarjian

As an example, he and I were on far opposite ends of the political spectrumIll let you guess which endsbut we never had a cross word about this.

Yes, he was larger than life, bombastic, abrasive, and politically incorrect at times. He was good at ruffling feathers, but he also had a sense of humor in abundance and a magnetism so irresistible that he made everyone who worked with him feel like they were the most important and favorite person to him.

If you asked the hundreds of researchers who worked with Freireich, each would categorically state that they were his favorite and they are carrying the torch of his legacy. And we all are.

Freireich always said, We are going to cure all the leukemias in my lifetime.

Initially, it was thought of as a pipe dream. When he started, none of the leukemias were curable. When I joined the MD Anderson faculty in 1981, only 20% of acute leukemias were cured, but none of the chronic leukemia were.

By 2018, all the chronic leukemiasCML and CLLhad become functionally or molecularly curable, and the cure rate of acute leukemia had reached more than 60-70%. We started to think his prophecy might actually be realized in his lifetime.

When I last saw him, in January 2021, over a span of a 30-minute conversation, he asked me three times, Are you happy? I replied each time in the affirmative.

Of course, I was sad in the moment, but to have spent 40 years with Freireich has made my life on this Earth very much worthwhile. I am the happiest person here because of him. Rest in peace, dearest friend of mine and of many others.

Your prophecy will come true very soon.

The author is professor and chairman,

Department of Leukemia,

Samsung Distinguished University Chair in Cancer Medicine,

MD Anderson Cancer Center

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Ode to J - The Cancer Letter