Category Archives: Human Longevity

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HONG KONG, Nov. 26, 2020 /PRNewswire/ -- Regent Pacific Group Limited ("Regent Pacific" or the "Company" and together with its subsidiaries, the "Group"; SEHK:0575.HK)'s Deep Longevity, Inc, a company subject to a conditional acquisition by the Group which is a pioneer in deep biomarkers of aging and longevity today announced a collaboration with My Care Express Merrillville to deploy an extensive range of AI-powered aging clocks. Deep Longevity is to develop and provide the customized predictors of human biological age to the network of My Care Express clinicians and to provide a training program in longevity medicine.

Deep Longevityaging clocks are supported by a number of academic publications summarized in a recent review titled "BioHorology and biomarkers of aging: Current state-of-the-art, challenges and opportunities"

My Care Express Merrillville has been a provider of preventative and total health care to its patients since it opened. My Care Express has a unique approach to wellness and longevity by helping patients establish wellness goals to live happier, healthier and longer lives. Deep Longevity and My Care Express will partner to see the impact that the utilization of aging clocks has on their patients. "We have always believed that the more information our patients have regarding their health, the better choices they will make. We believe that implementing aging clocks will give our patients a better understanding of their current health and help them achieve their wellness goals", said Dr. Faiz Shareef.

In the scope of the partnership My Care Express physicians will be trained in deep aging clocks and will be able to provide their customers with AgeMetric reports and engage in advanced research to assess the performance of aging clocks in the context of their wellness journey.

"The traditional approach to preventative medicine is focused on preventing disease by diagnosing the symptoms early or reducing the risks of disease. The AI-guided longevity medicine goes much further than that and is focusing on tracking the person's rates of aging at many levels, identification of longevity bottlenecks, and utilizing the latest advances in science and technology to slow down or reverse biological and psychological aging. We are very happy to have My Care Express join the rapidly growing network of our research and clinical partners focused on providing customers with extra years of productive and happy life", said Alex Zhavoronkov, Chief Longevity Officer of Deep Longevity Inc.

About Deep Longevity

Deep Longevity is subject to a conditional acquisition by Regent Pacific Group Limited (SEHK:0575.HK), a public company whose securities are listed on The Stock Exchange of Hong Kong Limited. Deep Longevity is developing explainable artificial intelligence systems to track the rate of aging at the molecular, cellular, tissue, organ, system, physiological, and psychological levels. It is also developing systems for the emerging field of longevity medicine enabling physicians to make better decisions on the interventions that may slow down, or reverse the aging processes. Deep Longevity developed Longevity as a Service (LaaS) solution to integrate multiple deep biomarkers of aging dubbed "deep aging clocks" to provide a universal multifactorial measure of human biological age. Originally incubated by Insilico Medicine, Deep Longevity started its independent journey in 2020 after securing a round of funding from the most credible venture capitalists specializing in biotechnology, longevity, and artificial intelligence. ETP Ventures, Human Longevity and Performance Impact Venture Fund, BOLD Capital Partners, Longevity Vision Fund, LongeVC, co-founder of Oculus, Michael Antonov, and other experts AI and biotechnology investors supported the company. Deep Longevity established a research partnership with one of the most prominent longevity organizations, Human Longevity, Inc. to provide a range of aging clocks to the network of advanced physicians and researchers.

http://longevity.ai/

About Regent Pacific (SEHK: 0575.HK)

Regent Pacific is a diversified investment group based in Hong Kong currently holding various corporate and strategic investments focusing on the healthcare, wellness, and life sciences sectors. The Group has a strong track record of investments and has returned approximately US$298 million to shareholders in the 21 years of financial reporting since its initial public offering.

http://www.regentpac.com/

About My Care Express Merrillville

My Care Express Merrillville is a clinic in Northwest Indiana that provides primary and urgent care with a focus on preventative medicine. My Care Express believes in a proactive approach to healthcare by providing its patients with tools that will help them live longer healthier lives. Located on the border of Indiana and Illinois, My Care Express has a dynamic and diverse practice. For more information visit mycareexpressclinic.com

SOURCE Regent Pacific Group Limited

http://www.regentpac.com

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Deep Longevity Adds Partnership with My Care Express in Merrillville To Add Biomarkers of Aging and Longevity - PRNewswire

GOOD nutrition, clean environments, accessibility to good healthcare and healthy lifestyles have increased human longevity. Nevertheless, the quest of increasing longevity is insatiable. As medical science pushes the boundaries of human lifespan, delving into the science of longevity can help us sieve through the reams of information and distil the essence of anti-ageing and cell preservation.

Cellular ageing

Cell ageing or cellular senescence is a physiological state with permanent cessation of the ability of the cell to replicate and accumulation of damaged DNA ( basic building blocks of genes), and this process is increased by ageing. This cellular senescence is marked by shortening of the protective terminal ends of the chromosomes which are called telomeres.

Telomeres are like plastic caps at the ends of shoelaces, preventing them from being frayed and damaged. Shortening of the telomere is a sign of cellular senescence.

In 1979, the first of the SIR (silent information regulator) proteins or sirtuins was reported. Over time more members of this protein group were found. In 1999, the publication of a study that reported that increased sirtuin activity could increase the lifespan of yeast cells by 70 per cent heralded a major breakthrough that accelerated the interest and research in sirtuins.

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Since then, there has been a growing body of evidence that the cell has a group of anti-ageing proteins, the sirtuins, that are essential for delaying cellular senescence and increasing the lifespan of organisms.

Anti-ageing proteins

Core to the science of anti-ageing is this group of proteins called sirtuins. In human cells, there are seven sirtuins (SIRT 1 to 7) with various roles within the cell. Three of these sirtuins (SIRT 3,4,5) control the generation of power for the needs of the cells and function in the mitochondria (power generator which produce the energy for the needs of the cell) with roles in cellular antioxidant balance and lipid metabolism.

Another three sirtuins (SIRT 1, 6, 7) control the genetic framework in the cell and function in the cell nucleus (the central core of the genetic material in the cell) with roles in gene expression and DNA repair. There is one sirtuin (SIRT 2 mainly) which control the environmental processes within the cell and function in the cytoplasm (the liquid content within the cell).

As an analogy, if the cell is a factory, the sirtuins are the executive management of the company directing and controlling all the aspects of the cell's activities. They play important roles in maintaining the integrity of the cellular genetic structure, keeping the genetic material (chromatin) in a "wound up" protected state to reduce damage and in repairing damaged DNA.

Mechanisms of action

The main mechanisms of suppression of cellular senescence by sirtuin activity is via the actions of preventing telomere shortening or attrition, and promoting the repair of damaged DNA.

Many proteins in the cells have a chemical tag called an acetyl group attached to it. One of the key ways in which sirtuins work is by the removal of the acetyl group from other molecules or proteins, thereby affecting the activity of the protein. This action has significant impact on the control centre of the cell, namely the activity of the genetic material or chromatin.

The basic building block of the genetic material, the DNA, is wrapped around groups of proteins called histones allowing the genetic material (chromatin) to be packed more compactly.

When the histone protein has the acetyl group chemical tag , it causes the chromatin to be partially unwound and hence exposing the unwound DNA to be copied, thereby allowing the gene instruction to be passed to another cell or protein. As an analogy, it is as if a door to the office is opened and people are allowed to go into the office to copy instructions which are then passed to other offices.

Once all the instructions are copied, the office door is closed. Hence, once the task is completed, the chromatin will not remain unwound as it will be more vulnerable to damage if it remains open.

Subsequently, the sirtuins can then remove the acetyl group from the histones which will then allow the chromatin to be closed by being "wound up" tightly, preventing DNA material from being copied and in effect silence the gene.

Besides histones, sirtuins target other non-histone proteins such as proteins involved in copying genetic information and proteins that are involved in the repair of DNA. They are also known to regulate the production of the enzyme telomerase which is required for telomere elongation and maintenance of the integrity of the telomere.

Most human cells have insufficient telomerase and hence there is progressive shortening of the telomere which is strongly indicative of progressive cellular ageing. Elongation of the chromosomal telomere is tantamount to reversing the biological clock.

Beneficial effects of sirtuin activity

Studies have shown that sirtuins have roles in the regulation of copying of gene information, modulation of energy production, prolongation of cell survival, reduction of DNA damage, reduction of cell damage and prolongation of longevity. Increased sirtuin activity in mammals has been associated with a delayed onset of age-related diseases and an increase in longevity.

Sirtuins appear to be able to inhibit axonal (nerve fibre) degeneration, a process that often precedes the death of nerve cells as seen in neurodegenerative diseases such as Parkinson's and Alzheimer's disease.

It may also have protective effect on nerve cells, reducing processes that lead to the death o f nerve cells and the development of Alzheimer's disease.

Loss of sirtuin activity has been implicated in the development of cardiovascular and metabolic diseases including degeneration of arteries, acute damage to the heart muscle, thickening of the heart muscle, abnormal heart rhythms, high blood pressure, obesity, diabetes mellitus and abnormal lipid levels. While most of the studies have been done in animals, there is an increasing number of human studies.

There is presently an increasing body of evidence that shows increased sirtuin activity is indispensable for delaying cellular senescence and appears to protect the body against many age related diseases. In addition, studies support the role of sirtuins as anti-aging agents and potentially prolong longevity.

Hence, lifestyle, dietary and pharmacological choices that increase sirtuin activity can potentially increase the anti-ageing effects and prolong longevity. These will be discussed in the next article where we will examine how we can make better decisions to increase our quality of life and lifespan.

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Unravelling the holy grail of anti-ageing and longevity - The Business Times

The recent report on the Longevity and Anti-senescence Therapy market predicts the industrys performance for the upcoming years to help stakeholders in making the right decisions that can potentially garner strong returns. Further, the document provides comprehensive analysis of the key industry trends as well as the opportunities that will ensure an upward growth trajectory in the coming years. It also focuses on developing strategies for challenges faced by the industry. Moreover, an exhaustive discussion of the latest updates including the impact of COVID-19 pandemic is furnished in the study.

Key highlights from COVID-19 impact analysis:

An overview of the regional landscape:

Request Sample Copy of this Report @ https://www.express-journal.com/request-sample/268954

Other important takeaways from the Longevity and Anti-senescence Therapy market report:

Key aspects listed in the report:

Points Covered in The Report:

The points that are discussed within the report are the major market players that are involved in the market such as manufacturers, raw material suppliers, equipment suppliers, end users, traders, distributors, etc.

The complete profile of the companies is mentioned. And the capacity, production, price, revenue, cost, gross, gross margin, sales volume, sales revenue, consumption, growth rate, import, export, supply, future strategies, and the technological developments that they are making are also included within the report. The historical data and forecast data from 2020 to 2025.

The growth factors of the market are discussed in detail wherein the different end users of the market are explained in detail.

Data and information by manufacturer, by region, by type, by application, etc., and custom research can be added according to specific requirements. The report contains a SWOT analysis of the market. Finally, the report contains the conclusion part where the opinions of the industrial experts are included.

Recent Industry Trend:

The report contains the profiles of various prominent players in the Global Longevity and Anti-senescence Therapy Market. Different strategies implemented by these vendors have been analyzed and studied to gain a competitive edge, create unique product portfolios and increase their market share. The study also sheds light on major global industry vendors. Such essential vendors consist of both new and well-known players. Besides, the business report contains important data relating to the launch of new products on the market, specific licenses, domestic scenarios and the strategies of the organization implemented on the market.

MAJOR TOC OF THE REPORT:

Chapter 1 Industry Overview

Chapter 2 Production Market Analysis

Chapter 3 Sales Market Analysis

Chapter 4 Consumption Market Analysis

Chapter 5 Production, Sales and Consumption Market Comparison Analysis

Chapter 6 Major Manufacturers Production and Sales Market Comparison Analysis

Chapter 7 Major Product Analysis

Chapter 8 Major Application Analysis

Chapter 9 Industry Chain Analysis

Chapter 10 Global and Regional Market Forecast

Chapter 11 Major Manufacturers Analysis

Chapter 12 New Project Investment Feasibility Analysis

Chapter 13 Conclusions

Chapter 14 Appendix

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Longevity and Anti-senescence Therapy Market size and Key Trends in terms of volume and value 2020-2025 - Express Journal

The Genomic Biomarker Market grew in 2019, as compared to 2018, according to our report, Genomic Biomarker Market is likely to have subdued growth in 2020 due to weak demand on account of reduced industry spending post Covid-19 outbreak. Further, Genomic Biomarker Market will begin picking up momentum gradually from 2021 onwards and grow at a healthy CAGR between 2021-2025

Deep analysis about market status (2016-2019), competition pattern, advantages and disadvantages of products, industry development trends (2019-2025), regional industrial layout characteristics and macroeconomic policies, industrial policy has also been included. From raw materials to downstream buyers of this industry have been analysed scientifically. This report will help you to establish comprehensive overview of the Genomic Biomarker Market

Get a Sample Copy of the Report at: https://i2iresearch.com/report/global-genomic-biomarker-market-2020-market-size-share-growth-trends-forecast-2025/#download-sample

The Genomic Biomarker Market is analysed based on product types, major applications and key players

Key product type:OncologyCardiologyNeurologyNephrology

Key applications:HospitalsDiagnostic and research laboratories

Key players or companies covered are:Bio-RadBeckman CoulterMyriad GeneticsThermo Fisher ScientificRocheQIAGENEpigenomicsAlmacPfizerHuman LongevityValiRxPersonalisEagle GenomicsEmpire GenomicsAgilentIllumina

The report provides analysis & data at a regional level (North America, Europe, Asia Pacific, Middle East & Africa , Rest of the world) & Country level (13 key countries The U.S, Canada, Germany, France, UK, Italy, China, Japan, India, Middle East, Africa, South America)

Inquire or share your questions, if any: https://i2iresearch.com/report/global-genomic-biomarker-market-2020-market-size-share-growth-trends-forecast-2025/

Key questions answered in the report:1. What is the current size of the Genomic Biomarker Market, at a global, regional & country level?2. How is the market segmented, who are the key end user segments?3. What are the key drivers, challenges & trends that is likely to impact businesses in the Genomic Biomarker Market?4. What is the likely market forecast & how will be Genomic Biomarker Market impacted?5. What is the competitive landscape, who are the key players?6. What are some of the recent M&A, PE / VC deals that have happened in the Genomic Biomarker Market?

The report also analysis the impact of COVID 19 based on a scenario-based modelling. This provides a clear view of how has COVID impacted the growth cycle & when is the likely recovery of the industry is expected to pre-covid levels.

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Genomic Biomarker Market Research Report 2020 with Business Overview and Manufacturers Profiles till 2026 - Cheshire Media

Roots Analysis has announced the addition of Microbiome Therapeutics Market, 2015-2030 report to their offering. The report provides a comprehensive study on the current landscape and the future outlook of the evolving pipeline of products in this area. While the field has garnered the interest of several companies, there are no approved microbiome drugs available in the market yet; Faecal Microbiota Transplant (FMT) is the only commercially available procedure till date. However, the development pipeline of microbiome therapeutics has several promising candidates that are likely to result in commercial success stories in the foreseen future.

Ishita Nanda, the principal analyst, said, Among other elements, the report also elaborates on new microbiome based diagnostic solutions being developed and the upcoming opportunities in this market for different stakeholders.One of the key objectives outlined for this report was to understand the future potential of the market. This was done by analyzing:

Nanda added, The study provides a detailed market forecast and opportunity analysis for the short-mid term (2015-2022) and long term (2022-2030). Our opinions and insights, presented in this study, were influenced by several discussions conducted with experts in this area. These included senior representatives at Assembly Biosciences, Da Volterra, Metabiomics, MicroBiome Therapeutics and Rebiotix.

The 218 page report includes detailed profiles and an assessment of the microbiome therapeutics programs of many companies including:

Details of some other firms developing microbiome related diagnostics and companion diagnostics have also been captured. Examples include (in alphabetical order) Admera Health, Biocartis, Enterome Bioscience, Human Longevity, Metabiomics, Microbiome Diagnostics, Viomer, Whole Biome.

For additional details, please visithttp://www.rootsanalysis.com/reports/view_document/microbiome-therapeutics-market-2015-2030/117.htmlor email[emailprotected]

About Roots Analysis

Roots Analysis is a specialist market research company, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If youd like us to help you with your growing business needs, get in touch at[emailprotected]

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Microbiome Therapeutics Market: What's the Future Potential? Roots Analysis - Cheshire Media

Precision Medicine Software Marketis anticipated to discover Robust Growth by 2026. This report focuses on the leading key players with global perspective with a professional and in-depth study on the current state of Precision Medicine SoftwareIndustry. Precision Medicine Softwaremarket research report provides important market strategies and Latest trends with discussion of market consumption, major drivers, restraints and market share forecasted to 2026.

The Precision Medicine Software Market Report further describes detailed information about tactics and strategies used by leading key companies in the Precision Medicine Softwareindustry. It also gives an extensive study about different market segments and regions.

The Precision Medicine Softwaremarket report provides answers to the following key questions:

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The Precision Medicine SoftwareMarket report provides basic information about Precision Medicine Softwareindustry, definition, classification, application, industry chain structure, industry overview; international market analysis. This report studies sales (consumption) of Precision Medicine Softwaremarket, focuses on the top players, with sales, price, revenue and market share with volume and value for each region.

Top Key Players in Precision Medicine Softwaremarket: Syapse, , Allscripts, , Qiagen, , Roper Technologies, , Fabric Genomics, , Foundation Medicine, , Sophia Genetics, , PierianDx, , Human Longevity, , Translational Software, , Gene42, Inc, , Lifeomic Health

Precision Medicine SoftwareMarket on the basis of Product Type:Cloud-based, , On-premise

Precision Medicine SoftwareMarket on the basis of Applications:Healthcare Providers, , Pharmaceutical and Biotechnology Companies, , Research Centers and Government Institutes, , Others,

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Impact of COVID-19:

Precision Medicine SoftwareMarket report analyses the impact of Coronavirus (COVID-19) on the Precision Medicine Softwareindustry.Since the COVID-19 virus outbreak in December 2019, the disease has spread to almost 180+ countries around the globe with the World Health Organization declaring it a public health emergency. The global impacts of the coronavirus disease 2019 (COVID-19) are already starting to be felt, and will significantly affect the Precision Medicine Softwaremarket in 2020.

The outbreak of COVID-19 has brought effects on many aspects, like flight cancellations; travel bans and quarantines; restaurants closed; all indoor events restricted; emergency declared in many countries; massive slowing of the supply chain; stock market unpredictability; falling business assurance, growing panic among the population, and uncertainty about future.

COVID-19 can affect the global economy in 3 main ways: by directly affecting production and demand, by creating supply chain and market disturbance, and by its financial impact on firms and financial markets.

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Key Questions Answered in this Report:

What is the market size of the Precision Medicine Softwareindustry?This report covers the historical market size of the industry (2013-2019), and forecasts for 2020 and the next 5 years. Market size includes the total revenues of companies.

What is the outlook for the Precision Medicine Softwareindustry?This report has over a dozen market forecasts (2020 and the next 5 years) on the industry, including total sales, a number of companies, attractive investment opportunities, operating expenses, and others.

What industry analysis/data exists for the Precision Medicine Softwareindustry?This report covers key segments and sub-segments, key drivers, restraints, opportunities, and challenges in the market and how they are expected to impact the Precision Medicine Softwareindustry. Take a look at the table of contents below to see the scope of analysis and data on the industry.

How many companies are in the Precision Medicine Softwareindustry?This report analyzes the historical and forecasted number of companies, locations in the industry, and breaks them down by company size over time. Report also provides company rank against its competitors with respect to revenue, profit comparison, operational efficiency, cost competitiveness and market capitalization.

What are the financial metrics for the industry?This report covers many financial metrics for the industry including profitability, Market value- chain and key trends impacting every node with reference to companys growth, revenue, return on sales, etc.

What are the most important benchmarks for the Precision Medicine Softwareindustry?

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Precision Medicine Software Market 2020: Potential growth, attractive valuation make it is a long-term investment | Know the COVID19 Impact | Top...

We have been told about the importance of protecting gut health as a measure to take care of overall health. Do you know what probiotics are and what are they for? These live bacterial cultures have become one of the best allies to protect intestinal health. Any gut doctor can advise you on their importance.

They are critical to the synthesis of some essential nutrients and to maintain optimal digestive health. Likewise, they create a protective barrier against infections and act beneficially on some inflammatory processes. Although they exist naturally in the body, they can be consumed through some fermented or dairy foods as well as food supplements. You should look for the best probiotic supplements that will keep your gut in perfect shape.

Probiotics are good bacteria and yeasts. They survive passage through the gastrointestinal tract to implant in the colon and small intestine. Although many associate bacteria with the disease, their role is very different.

Probiotics can stop the excessive growth of infectious microorganisms. Therefore, they are key to preventing the development of various pathogens. Those most used for human benefit are lactobacilli and bifidobacteria.

To sum it up, these non-harmful bacteria and yeasts occupy sites where pathogenic microorganisms could implant. By not leaving room for them and favoring some processes such as digestion, they are beneficial.

The gastrointestinal tract is packed with about 400 bacterial species. Among its primary functions is to protect the body against the proliferation of pathogens responsible for many conditions.

They are also responsible for controlling the differentiation of epithelial cells. They are also involved in metabolic processes and the production of vitamins. Therefore, it is essential to have a balanced intestinal flora rich in healthy bacteria.

Probiotics are the best alternative to improve gut health. Here are the benefits of probiotics.

There is nothing worse than having diarrhea. If youre suffering from diarrhea caused by an infection, probiotics can help you heal faster and lessen the severity of your symptoms. It will get rid of all the elements that bring about stomach pain. Using it will not affect some of the good bacteria in your gut.

Are you taking antibiotics? Probiotics can help rebalance your gut. Taking antibiotics kills the harmful bacteria that are causing your infection. However, it can also kill the good bacteria in your gut, leading to diarrhea in some people. Probiotics can play a pivotal role in replenishing some of the good bacteria destroyed by the drugs.

Irritable Bowel Syndrome is a condition affecting the stomach. It causes severe pain and problems, including constipation, diarrhea, or a combination of the two. It is a syndrome that affects around 10% to 15% of the population. Research shows that bacteria can play an essential role in this syndrome. Probiotics have shown promise in improving IBS symptoms, especially in people who experience diarrhea more often.

Are you going on a trip? Consider bringing probiotics. We all want to focus on the fun things to do, local food, and sightseeing while on vacation. That said, theres nothing worse than having your trip ruined by an unexpected episode of tourista. Fortunately, probiotics containing specific strains of bacteria and yeast have shown promise in this regard. If you plan on taking a probiotic while traveling, remember to choose one that doesnt need to be refrigerated. Ask your pharmacist to help you select a product if in doubt.

Different types of probiotics have other health effects. Many of the effects of probiotics take place via multiple actions of these on the gut flora:

Now that we know what probiotics are for, it is good to know their sources. Here are some of its sources.

Fermented foods contain probiotics. The most popular include:

Not all people get enough probiotics through diet. Considering their importance for health, the option of including them in supplements is an excellent idea. Supplements are available in capsules, powders, and other similar products. These contain large concentrations of microorganisms, beneficial, and protective of health.

Some presentations are enriched with prebiotics, which are foods that promote the growth of these good bacteria. Therefore, in many cases, these products are more effective than the probiotics that come from the traditional diet. In other words, a prebiotic food is one that favors the growth of beneficial microorganisms. And a probiotic is one that directly contains those healthy beings.

Bowel balance is good for your general health. We are learning a lot of things about probiotics every day, and the proof for their benefits keeps growing. If you want to add probiotics to your life, talk to a qualified pharmacist or healthcare professional. They will help choose the product thats best for you.

The gut is regularly referred to as the second brain because the gut microbiome can have a big impact on your body, including the state of your hair. That said, the gut microbiome can be affected by your lifestyle choices and anything that throws it off balance can compromise your health, as well asaffect the health of your locks. So, heres how a healthy gut can help prevent hair loss.

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5 Benefits of Probiotics for Gut Health - Longevity LIVE - Longevity LIVE

None of the mutations observed in the coronavirus that causes COVID-19 appear to increase the viruss transmissibility, a new study says.

The study led by researchers from University College London published Wednesday in Nature Communications analyzed a global dataset of virus genomes from more than 46,000 people with COVID-19 from 99 countries.

Our country is in a historic fight against the Coronavirus. Add Changing America to your Facebook or Twitter feed to stay on top of the news.

Researchers so far have identified more than 12,700 mutations in the SARS-CoV-2 virus.

Coronaviruses like SARS-CoV-2 mutate all the time and most are neutral. But some can be advantageous or detrimental to the virus, potentially with troublesome consequences, such as making the virus more contagious and a vaccine less effective.

But so far, researchers say they have yet to find any evidence common mutations are increasing the viruss transmissibility.

We realised early on in the pandemic that we needed new approaches to analyze enormous amounts of data in close to real time to flag new mutations in the virus that could affect its transmission or symptom severity, Lucy van Dorp, a professor at University College Londons Genetics Institute and a lead researcher of the study, said in a statement.

Fortunately, we found that none of these mutations are making COVID-19 spread more rapidly, but we need to remain vigilant and continue monitoring new mutations, particularly as vaccines get rolled out, she said.

Researchers found most of the viruss mutations occurred as a result of the human immune system response, rather than the result of the virus adapting to its human host.

Over the course of the pandemic, one mutation in the virus spike protein called D614Gwas reported as being a mutation that could make the virus more contagious than earlier strains that emerged out of Wuhan, China.

The study published Wednesday found the mutation is in fact not associated with a greater increase in transmission.

Francois Balloux, a UCL professor who worked on the research, said the virus posed no threat to COVID-19 vaccine efficacy at this time but warned the introduction of vaccines could exert new selective pressures on the virus to mutate to escape recognition by the humane immune system.

The news on the vaccine front looks great. The virus may well acquire vaccine-escape mutations in the future, but were confident well be able to flag them up promptly, which would allow updating the vaccines in time if required, Balloux said.

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Mutations of the coronavirus do not appear to make the virus more infectious, study says | TheHill - The Hill

Simone Faurschous jewellery is inspired by human connection and isolation

The young designers new line Pangea is inspired by togetherness

Pangea the ancient supercontinent that once existed many millions of years ago when all the continents as we know them today were joined together is the inspiration for Simone Faurschous new jewellery line. Pangea was a time where the world was less fragmented and all continents were still one large piece of land, says the designer, speaking from her London studio.

Moreover, Faurschou is drawn to the human connectedness that a singular landmass evokes, something that has been pertinently lacking for many this year. Humans are born wired for connection its in our DNA, as strong a need as food, water and warmth. Social connection has been proven to lower anxiety, as well as depression, and when we experience human connectedness as individuals, it helps regulate our emotions and our immune systems even improve.

Two fragments from the Pangea collection

Although in the nascent stages of her career, Faurschou has a solid jewellery pedigree having studied jewellery design at Central Saint Martins and most recently was the head of design at Completed Works. To launch her new line, the poet Wilson Oreyma created a poem for her called Pangea.

She calls each piece in the collection a fragment; a small, delicate slice of polished gold that can be hung from a necklace chain or an earring hoop. The fragment is a talisman and reminder of the great value of universal human connectedness, she says. I decided to name each fragment connectedness in multiple languages from across the world: Motassel means connectedness in Serbian; Forbundethed in Danish; Umoja in Swahili; Altarabut in Arabic. Language connects us, and is part of what makes us human and distinguishes us from other species, and has also evolved since the beginning of time.

With the earths longevity being so central to her design inspiration, it followed that its preservation should be equally as considered. I did a lot of research before setting up my business. In a world full of over-consumption, I wanted to create timeless pieces without compromising people and the environment. I wanted 100 per cent supply chain traceability first of all and this led me to become a proud Fairmined licensee. Fairmined is an incredible organisation and international assurance label that certifies gold from responsible artisanal and small-scale mining organisations. It is a way of ensuring that the precious metals are mined and processed in ways that are socially and environmentally responsible, she explains.

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Faurschou plans to expand the line with designs for a bracelet, ear cuffs, earrings and rings. She is also working on a bridal jewellery line, and customisation with birthstones and engraving. Human connectedness is such a powerful universal need and the Pangea collection was created to spread this message, she says.

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Simone Faurschous jewellery is inspired by human connection and isolation - Wallpaper*