Category Archives: Genome

Scientists have recently completed their work sequencing the barley genome, which could lead to better or less-expensiveScientists with the International Barley Genome Sequencing Consortium have recently completed their work sequencing the barley genome, which is even larger than the human genome.

The goal of this research is to gain a better understanding of barley and how to make its cultivars the various types of barley that have been selectively grown for their specific characteristics higher in dietary fibre, more resistant to diseases and climate change, and possibly to create better or less-expensive beer.

[ Related: Wheat, soybeans, potatoes could be replaced in warmer climate ]

The data, published last month in Nature, is a draft-work, showing that roughly two-thirds of the total sequence of genes has been mapped. Nils Stein (what a great name for a barley researcher!) is head of the Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), and the lead researcher of this work. He hopes that this will give them a better knowledge of how gene expression is controlled in the barley plant, which could lead to ways for plant breeders to have more control over them in the production of new cultivars.

Stein and his team also compared the genomes of two-row barley and six-row barley. Two-row barley is lower in protein content than six-row barley, and is traditionally used for English ales and German beers, whereas six-row barley is used in American lagers, especially when corn or rice are used as adjuncts. They found that many of the active genes of these cultivars are located where they are not accessible when using selective breeding methods, however according to Popular Science, Stein says that gene modification techniques might be used to specifically target those genes.

[ Related: Cloned cow produces super nutritious, hypo-allergenic milk for kids ]

This completed sequence may also make an excellent model for understanding more complicated genome sequences, like that of wheat, which could then lead to better disease resistance and environmental tolerances for one of the most important staple foods we grow.

For all the latest in science and weather, follow @ygeekquinox on Twitter.

Original post:
Barley genome breakthrough might lead to better, cheaper beer

Public release date: 7-Nov-2012 [ | E-mail | Share ]

Contact: Cathy Yarbrough press@ashg.org 858-243-1814 American Society of Human Genetics

Whole genome sequencing of the DNA code of three prenatal samples provided a detailed map of the locations of their chromosomal abnormalities in 14 days, scientists reported today at the American Society of Human Genetics (ASHG) 2012 meeting in San Francisco.

"Such a relatively brief timeframe will enable physicians to predict diagnosis of serious congenital disorders prenatally to counsel the parents and plan perinatal care of infants with chromosomal rearrangements," said Zehra Ordulu, M.D., Brigham and Women's Hospital and Harvard Medical School medical research fellow in obstetrics, gynecology and reproductive biology, who presented the study.

In the study, whole genome sequencing was used after current prenatal diagnostic methods of karyotyping and array comparative genomic hybridization (aCGH) to provide nucleotide level precision were conducted.

Karyotyping and aCGH studies of the prenatal samples provided the first clues of "balanced de novo chromosomal rearrangements," and prompted the investigation by genomic sequencing.

Clinical consequences of such chromosome rearrangements, which are defined as the relocation of chromosome segments without any loss or gain in genomic material, are rare, not inherited and challenging to predict without knowledge of the precise breakpoints.

"Unlike karyotyping, aCGH and other standard methods, whole genome sequencing provided the information to detect the 'breakpoints" in the chromosomes at which the rearrangements occurred and thereby to determine the genomic regions altered," said Cynthia C. Morton, Ph.D., William Lambert Richardson Professor in obstetrics, gynecology and reproductive biology, professor of pathology at Brigham and Women's Hospital and Harvard Medical School and incoming president-elect of ASHG.

"Early detection of a genetic disorder is of significant importance for informing genetic counseling and for managing the pregnancy, birth and further clinical follow-up," said Dr. Morton, who headed the study.

"This study foretells an empowered prenatal diagnostic environment in which DNA sequencing becomes the standard of care," she added.

Read the original here:
Whole genome sequencing of de novo balanced rearrangements in prenatal diagnosis

Rehearsal, Genome #1
Rehearsal, Genome #1From:Anthony PursellViews:8 0ratingsTime:05:29More inMusic

See the article here:
Rehearsal, Genome #1 - Video

Concert Footage: Fraley: Genome IV-V
Rehearsal Concert FootageFrom:Anthony PursellViews:5 0ratingsTime:08:45More inMusic

Visit link:
Concert Footage: Fraley: Genome IV-V - Video

Primerlife (Skolkovo Foundation)
Primerlife company (primerlife.sk.ru presentation on the Open Innovations 2012. Primerlife is the system of genetic data interpretation and consultation with genetic counselors. Primerlife as a platform is the attraction of all categories of users interested in the use of personal genetic information: Users / patients who are interested in interpreting the analysis of their personal genetic information and getting consultations about it; Genetic experts interested in increasing the number of their customers, improvement in their professional reputation, and access to convenient tools for more effective service delivery (communication platform with patients and the tools of genome interpretation); Pharmaceutical companies interested in the use of anonymized database of users genotypes; Advertisers who are interested in the most efficient coverage of the target audience.From:iSkolkovoViews:0 0ratingsTime:01:03More inScience Technology

Go here to see the original:
Primerlife (Skolkovo Foundation) - Video

Profile: Susan Perkins
Dr. Susan Perkins is a microbiologist with three main areas of research. The first is the systematic, biogeographic, and molecular evolutionary study of the protozoan parasites that cause malaria, including those that infect non-human hosts. Her second main research focus is the study of symbiotic bacteria that are found in certain groups of blood-feeding leeches. This project involves both morphological and molecular work and will soon enter the realm of genomics, as the hope is to sequence the entire genome of one type of these symbionts. The third research focus is an examination of the patterns of genomics and geography, in relation to pathogenicity, of RNA viruses. For more interviews, visit our "Meet the Scientists" channel: http://www.amnh.orgFrom:AMNHorgViews:51 5ratingsTime:03:04More inScience Technology

Read more:
Profile: Susan Perkins - Video

Diastrophic Dysplasia - A Bibliography And Dictionary For Physicians, Patients, And Genome Researche
ll4.me Diastrophic Dysplasia - A Bibliography And Dictionary For Physicians, Patients, And Genome Researchers - Icon Health Publications This is a 3-in-1 reference book. It gives a complete medical dictionary covering hundreds of terms and expressions relating to Diastrophic dysplasia. It also gives extensive lists of bibliographic citations. Finally, it provides information to users on how to update their knowledge using various Internet resources. The book is designed for physicians, medical students preparing for Board examinations, medical researchers, and patients who want to become familiar with research dedicated to Diastrophic dysplasia. If your time is valuable, this book is for you. First, you will not waste time searching the Internet while missing a lot of relevant information. Second, the book also saves you time indexing and defining entries. Finally, you will not waste time and money printing hundreds of web pages.Author: ICON Health Publications Publisher: ICON Health Publications Illustration: N Language: ENG Title: Diastrophic Dysplasia - A Bibliography and Dictionary for Physicians, Patients, and Genome Researchers Pages: 00116 (Encrypted PDF) On Sale: 2007-07-20 SKU-13/ISBN: 9780497113681 Category: Medical : Diseases This is a 3-in-1 reference book. It gives a complete medical dictionary covering hundreds of terms and expressions relating to Diastrophic dysplasia. It also gives extensive lists of bibliographic cit icon health publications, medical ...From:juliansawyers9865Views:0 0ratingsTime:00:13More inPeople Blogs

Read the rest here:
Diastrophic Dysplasia - A Bibliography And Dictionary For Physicians, Patients, And Genome Researche - Video

Spondyloperipheral Dysplasia - A Bibliography And Dictionary For Physicians, Patients, And Genome Re
ll4.me Spondyloperipheral Dysplasia - A Bibliography And Dictionary For Physicians, Patients, And Genome Researchers - Icon Health Publications This is a 3-in-1 reference book. It gives a complete medical dictionary covering hundreds of terms and expressions relating to Spondyloperipheral dysplasia. It also gives extensive lists of bibliographic citations. Finally, it provides information to users on how to update their knowledge using various Internet resources. The book is designed for physicians, medical students preparing for Board examinations, medical researchers, and patients who want to become familiar with research dedicated to Spondyloperipheral dysplasia. If your time is valuable, this book is for you. First, you will not waste time searching the Internet while missing a lot of relevant information. Second, the book also saves you time indexing and defining entries. Finally, you will not waste time and money printing hundreds of web pages.Author: ICON Health Publications Publisher: ICON Health Publications Illustration: N Language: ENG Title: Spondyloperipheral Dysplasia - A Bibliography and Dictionary for Physicians, Patients, and Genome Researchers Pages: 00100 (Encrypted PDF) On Sale: 2007-07-19 SKU-13/ISBN: 9780497112981 Category: Medical : Diseases This is a 3-in-1 reference book. It gives a complete medical dictionary covering hundreds of terms and expressions relating to Spondyloperipheral dysplasia. It also gives extensive lists of bibliograp icon ...From:juliansawyers9865Views:0 0ratingsTime:00:14More inPeople Blogs

More:
Spondyloperipheral Dysplasia - A Bibliography And Dictionary For Physicians, Patients, And Genome Re - Video

Living Philosophy - Ray Billington
ll4.me Living Philosophy - Ray Billington "Living Philosophy: An Introduction to Moral Thought, third edition" is a thoroughly revised and updated version of its highly successful and popular predecessor. Incorporating several brand new case studies and discussion points, the book introduces central questions in ethical theory to the student and assumes no previous knowledge of philosophy. Each chapter deals with a particular ethical issue and has an accompanying case study designed to encourage discussion. New topics raised include genetically modified organisms (GMO), environmental ethics, bioethics and the human genome, as well as a new chapter on religious and cultural relativism in the light of september 11th. Ray Billington #39;s style is at once refreshing and honest and his approach to the subject is always clear. The coverage of the book is tailored for any introductory course in ethics.Words: 11th september, september 11thAuthor: Billington, Ray Publisher: Routledge Illustration: N Language: ENG Title: Living Philosophy Pages: 00000 (Encrypted PDF) On Sale: 2003-02-20 SKU-13/ISBN: 9780415284462 Category: Education : Teaching Methods Materials - Arts Humanities "Living Philosophy: An Introduction to Moral Thought, third edition" is a thoroughly revised and updated version of its highly successful and popular predecessor. Incorporating several brand new case books for pdas, philosophy, ray billington, education, teaching methods, materials, arts, humanitiesFrom:jenniferwyant9865Views:0 0ratingsTime:00:16More inPeople Blogs

Continue reading here:
Living Philosophy - Ray Billington - Video

Charcot-marie-tooth Disease - A Bibliography And Dictionary For Physicians, Patients, And Genome Res
ll4.me Charcot-marie-tooth Disease - A Bibliography And Dictionary For Physicians, Patients, And Genome Researchers - Icon Health Publications This is a 3-in-1 reference book. It gives a complete medical dictionary covering hundreds of terms and expressions relating to Charcot-Marie-Tooth disease. It also gives extensive lists of bibliographic citations. Finally, it provides information to users on how to update their knowledge using various Internet resources. The book is designed for physicians, medical students preparing for Board examinations, medical researchers, and patients who want to become familiar with research dedicated to Charcot-Marie-Tooth disease. If your time is valuable, this book is for you. First, you will not waste time searching the Internet while missing a lot of relevant information. Second, the book also saves you time indexing and defining entries. Finally, you will not waste time and money printing hundreds of web pages.Author: ICON Health Publications Publisher: ICON Health Publications Illustration: N Language: ENG Title: Charcot-Marie-Tooth Disease - A Bibliography and Dictionary for Physicians, Patients, and Genome Researchers Pages: 00224 (Encrypted PDF) On Sale: 2007-07-20 SKU-13/ISBN: 9780497113506 Category: Medical : Diseases This is a 3-in-1 reference book. It gives a complete medical dictionary covering hundreds of terms and expressions relating to Charcot-Marie-Tooth disease. It also gives extensive lists of bibliograph icon health ...From:susansantigo9847Views:0 0ratingsTime:00:10More inPeople Blogs

Go here to see the original:
Charcot-marie-tooth Disease - A Bibliography And Dictionary For Physicians, Patients, And Genome Res - Video