Category Archives: Genome

Washington, May 29 (ANI): Researchers at the Vetmeduni Vienna have sequenced the genome of a Bactrian camel, making a significant contribution to population genetic research on camels.

The study has laid the foundation for future scientific work on these enigmatic desert animals. A blood sample from a single Bactrian camel with the evocative name of "Mozart" provided the genetic raw material for the work, which was undertaken by Pamela A. Burger at the Institute of Population Genetics.

Camels are divided into two species, the one-humped dromedary and the two-humped Bactrian camel. Whether equipped with one or two humps, camels are precious in desert regions throughout the world. Their ability to carry heavy loads over long distances makes them ideally suited for transportation.

In addition, camels are able to survive for weeks in hostile environments without food and water. Despite the extremely arid conditions, camels still provide enough milk for human consumption and also have an important role as a source of meat. Camels are specialists when it comes to adapting to the environment and have been characterized as sustainable food producers.

Pamela Burger heads one of the few research groups in Europe that study camel genetics. Burger and her colleagues are primarily interested in the domestication of camels, which took place around 3,000 to 6,000 years ago.

Genetic data provide important clues on the breeding strategies and selection processes that were applied by humans at that time. The DNA code also represents a rich resource for addressing questions on phylogenetic relationships between animals. Burger is one of the first scientists to sequence large parts of the genome of a Bactrian camel and make it available to the public.

Until recently, the genetic code of the Camel had not been fully analysed. Genetic research on these animals was therefore difficult or even impossible. In contrast, the entire genetic information of the human genome was available as long ago as 2003 and the genetic code of various animals and plants is publicly available, giving researchers access to an enormous set of data.

To date, the lack of basic genetic data has severely hampered studies of camel genetics. Pamela Burger and her team are pioneers in presenting this essential dataset.

The scientists were able to find 116,000 so-called SNPs (single nucleotide polymorphisms) in the genetic sequence of the Bactrian camel. SNPs are single base-pair changes within a DNA strand that provide the basis for studying relationships among species and between single animals.

The genetic relationship between the Bactrian camel (Camelus bactrianus) and the dromedary (Camelus dromedarius) is close. 85 percent of the genomic sequences expressed in the dromedary can be found in the Bactrian camel.

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Camel genome decoded for first time

Interpreting Variants in Non-Coding Regions of the Genome - Lisa Brooks
May 20, 2013 - National Advisory Council for Human Genome Research More: http://www.genome.gov/27553774.

By: GenomeTV

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Interpreting Variants in Non-Coding Regions of the Genome - Lisa Brooks - Video

Genome Sequencing Program Update: Disease 2020 - Adam Felsenfeld
May 20, 2013 - National Advisory Council for Human Genome Research More: http://www.genome.gov/27553774.

By: GenomeTV

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Genome Sequencing Program Update: Disease 2020 - Adam Felsenfeld - Video

ACMG Recommendations for Reporting of Incidental Findings in Clinical Exome and Genome Sequencing
May 20, 2013 - National Advisory Council for Human Genome Research Speaker: Robert Nussbaum More: http://www.genome.gov/27553774.

By: GenomeTV

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ACMG Recommendations for Reporting of Incidental Findings in Clinical Exome and Genome Sequencing - Video

Brian Cox Preview - The Incomplete Map of the Cosmic Genome
A preview clip from the upcoming app The Incomplete Map of the Cosmic Genome featuring Professor Brian Cox discussing the role of electrons. The app features hours and hours of extensive,...

By: Trunkman Productions

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Brian Cox Preview - The Incomplete Map of the Cosmic Genome - Video

Striking a blow at foodborne diseases, the 100K Pathogen Genome Project at UC Davis announced that it has sequenced the genomes of its first 10 infectious microorganisms, including strains of Salmonella and Listeria.

"We are creating a free, online encyclopedia or reference database of genomes so that during a foodborne disease outbreak, scientists and public health professionals can quickly identify the responsible microorganism and track its source in the food supply using automated information-handling methods," said Professor Bart Weimer, director of the 100K Genome Project and co-director of BGI@UC Davis, the Sacramento facility where the sequencing is carried out.

Weimer estimates that the availability of this genomic information will cut in half the time necessary to diagnose and treat foodborne illnesses, and will enable scientists to make discoveries that can be used to develop new methods for controlling disease-causing microorganisms in the food chain.

The project is dedicated to sequencing the genomes of 100,000 bacteria and viruses that cause serious foodborne illnesses in people around the world.

In the United States alone, foodborne diseases annually sicken 48 million people and kill 3,000, according to the Centers for Disease Control and Prevention.

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UCDavis Genome Project maps infectious microbes

Colony Collapse Disorder and the WSU Honey Bee Genome Repository
A lot of challenges face honeybees. Invasive mites sap the brood #39;s strength and introduce disease. Pesticide build-up in the brood comb gradually weakens the bees. And monocultures may provide...

By: Agricultural, Human, and Natural Resource Sciences

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Colony Collapse Disorder and the WSU Honey Bee Genome Repository - Video

Infosys Consumer Genome

By: 3storeys

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Infosys Consumer Genome - Video

April Flowers for redOrbit.com Your Universe Online

The genomes of two of the most economically important forest trees in the world were released by Canadian and Swedish scientists. In Canada, the conifers supply raw materials for the forest industry, accounting for $23.7 billion of the nations economy in 2011, while the gross output of the Swedish forest industry was $29.7 billion in 2009.

Between them, the white spruce and the Norway spruce genomes have 20-30 billion base-pairs and are up to 10 times larger than the human genome, making these sequence assemblies the largest to date.

THE WHITE SPRUCE

A group of Canadian scientists, led by Professor Steven Jones, Head of Bioinformatics at the BC Cancer Agency Genome Sciences Centre (BCGSC) and a professor at both the University of British Columbia (UBC) and Simon Fraser University (SFU), sequenced the white spruce genome as part of the SMarTForests Project.

SMarTForests builds upon previous discoveries of the past decade to break new ground in spruce genome sequencing in order to represent Canada in international conifer genome initiatives and to achieve efficient translation of results toward end-users from across Canada.

Attempting the sequencing of such a large genome was an incredibly ambitious task and required the development of novel software and innovative use of DNA sequence technology to piece together short DNA sequences to form this massive genome, much like a large jigsaw puzzle, said Jones. The findings of this study were published in the journal Bioinformatics.

Many projects are now attempting to decipher genomes of economically important plants, Inanc Birol, a scientist with BCGSC and a professor with both UBC and SFU, said in a statement. We demonstrated a superior and less expensive method to do the job.

These genome sequences allow us to develop innovative tools for tree breeding, addressing economically and ecologically important targets such as insect resistance, wood quality, growth rates and adaptation to changing climate added UBC Prof. Joerg Bohlmann, a collaborator on both studies.

A genome-based marker system could serve to reduce the time of a spruce breeding cycle from currently 25 to as short as five years, and will contribute directly to the competitiveness of the Canadian and Scandinavian forest industry, said Prof. John MacKay of Universit Laval, who also participated in both studies.

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Researchers Map Genome Of Two Important Spruce Tree Species

DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/5b54vr/us_personalized) has announced the addition of the "US Personalized Cancer Genome Sequencing Market" report to their offering.

The US personalized cancer Genome Sequencing market is primarily classified into Targeted Genome Sequencing and Whole-Genome Sequencing. Our report entitled US Personalized Cancer Genome Sequencing Market takes into account the Whole-Genome Sequencing services, which is one of the most attractive sectors due to its inherent capability of high revenue generation and efficiency in terms of personalized treatment.

In order to properly analyze the virtues and significance of the US personalized cancer Whole-Genome Sequencing market, our report has effectively studied the current and future status of cancer in the US as well as its States. In view of the fact that cancer affects some specific age groups in a significant manner, we have also investigated the age-wise statistics of the disease. To get proper insight into the market, an in-depth analysis into the high-income group population is provided so that players can have a clear picture about their potential customer base and the market to be tapped.

The WGS industry has evolved in US in the recent times, and the level and seriousness of implementation has seen drastic changes. An in-depth study of the regulatory environment governing the US personalized cancer Whole-Genome Sequencing market has also been provided. It has been found that regulations related to personalized cancer sequencing are primarily governed with the accreditation of the laboratories performing the sequencing services and analysis, and also the usage of FDA approved tests for conducting these tests. Further, we have also discussed the various constraints faced by the industry players with suitable suggestions to overcome them.

The report analyzes the competitive landscape in the market by properly analyzing the business, services and activities of the companies. It also provides the competitive benchmarking, taking into account the strengths and weaknesses of each player. Overall, the report is a complete source of knowledge and statistics for the clients who want to get an in-depth understanding of the market.

Key Topics Covered:

1. Analyst View

2. Research Methodology

3. Cancer Statistics by Demographics

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Research and Markets: US Personalized Cancer Genome Sequencing Market Report: 2013 Edition