Category Archives: Genome

Bacterial Genome COG
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Bio305 Bacterial Genome Dynamics and Evolution
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Dynamic Genome Outreach Group at UCR does a strawberry DNA extraction en espaol!
DGOG got together on Sunday June 9th at the Neil A. Campbell Science Learning Laboratory at UCR to record a how-to video on strawberry DNA extraction en espaol! Enjoy and share with your...

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Dynamic Genome Outreach Group at UCR does a strawberry DNA extraction en español! - Video

How to Sequence a Genome 1 Mapping - A-Level (A2) Biology
For A Level Biology, suited for Unit 5 of the OCR exam board.

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June 9, 2013 The duck genome consortium, consisted of scientists from China Agricultural University, BGI, University of Edinburgh and other institutes has completed the genome sequencing and analysis of the duck (Anas platyrhynchos), one principal natural host of influenza A viruses, which caused a new epidemic in China since this February. This work reveals some noteworthy conclusions and provides an invaluable resource for unraveling the interactive mechanisms between the host and influenza viruses.

The new H7N9 bird flu strain killed 36 people and caused $6.5 billion loss to China's economy. As a natural host of influenza A viruses (including H5N1), the duck is known to often remain asymptomatic under influenza infection. To uncover the interactive mechanisms between the host and influenza viruses, researchers sequenced the genome of a 10-week-old female Beijing duck, and conducted transcriptomic studies on two virus-infected ducks.

This work yielded the draft sequence of a waterfowl-duck for the first time, and the data indicated that the duck, like the chicken and zebra finch, possessed a contractive immune gene repertoire comparing to those in mammals, and it also comprises novel genes that are not present in the other three birds (chicken, zebra finch and turkey).

By comparing gene expression in the lungs of ducks infected with either highly or weakly pathogenic avian influenza H5N1 viruses, the team identified genes whose expression patterns were altered in response to avian influenza viruses. They also identify factors that may be involved in duck host immune response to avian virus infection, including the avian and mammalian -defensin gene families.

Jianwen Li, project manager from BGI, said, "This study provides very important data to better understand the interaction between the host and the avian influenza. Scientists will be able to explore more deeply the mechanisms on the spread and infection of avian influenza."

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The above story is reprinted from materials provided by BGI Shenzhen.

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Duck genome provides new insight into fighting bird flu

Public release date: 9-Jun-2013 [ | E-mail | Share ]

Contact: Jia Liu liujia@genomics.cn BGI Shenzhen

Shenzhen, China - The duck genome consortium, consisted of scientists from China Agricultural University, BGI, University of Edinburgh and other institutes has completed the genome sequencing and analysis of the duck (Anas platyrhynchos), one principal natural host of influenza A viruses. This work reveals some noteworthy conclusions and provides an invaluable resource for unraveling the interactive mechanisms between the host and influenza viruses.

The new H7N9 bird flu strain killed 36 people and caused $6.5 billion loss to China's economy. As a natural host of influenza A viruses (including H5N1), the duck is known to often remain asymptomatic under influenza infection. To uncover the interactive mechanisms between the host and influenza viruses, researchers sequenced the genome of a 10-week-old female Beijing duck, and conducted transcriptomic studies on two virus-infected ducks.

This work yielded the draft sequence of a waterfowl-duck for the first time, and the data indicated that the duck, like the chicken and zebra finch, possessed a contractive immune gene repertoire comparing to those in mammals, and it also comprises novel genes that are not present in the other three birds (chicken, zebra finch and turkey).

By comparing gene expression in the lungs of ducks infected with either highly or weakly pathogenic avian influenza H5N1 viruses, the team identified genes whose expression patterns were altered in response to avian influenza viruses. They also identify factors that may be involved in duck host immune response to avian virus infection, including the avian and mammalian -defensin gene families.

Jianwen Li, project manager from BGI, said, "This study provides very important data to better understand the interaction between the host and the avian influenza. Scientists will be able to explore more deeply the mechanisms on the spread and infection of avian influenza."

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About BGI

BGI was founded in Beijing, China, in 1999 with the mission to become a premier scientific partner for the global research community. The goal of BGI is to make leading-edge genomic science highly accessible, which it achieves through its investment in infrastructure, leveraging the best available technology, economies of scale, and expert bioinformatics resources. BGI, and its affiliates, BGI Americas, headquartered in Cambridge, MA, and BGI Europe, headquartered in Copenhagen, Denmark, have established partnerships and collaborations with leading academic and government research institutions as well as global biotechnology and pharmaceutical companies, supporting a variety of disease, agricultural, environmental, and related applications.

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The duck genome provides new insight into fighting bird flu

PEET SHOX - Dedicated 2 Genome (Really Mad)
Trochu syrov #283;j scaron; a tvrd scaron; Track, v #283;novan speciln #283; pro Marka B. aka Genome... HardHouse Hardcore Styles Forever!!!

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Intro to my online Human Genome and Bioinformatics summer class at UIUC
This is the introductory video I made to welcome my students to my Human Genome and Bioinformatics class that I teach online at UIUC with the School of Integ...

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Intro to my online Human Genome and Bioinformatics summer class at UIUC - Video

Copyright 2013 NPR. For personal, noncommercial use only. See Terms of Use. For other uses, prior permission required.

IRA FLATOW, HOST:

This is SCIENCE FRIDAY; I'm Ira Flatow. If you're thinking about getting married or having children or just contemplating your health care options, you or your doctor may decide to have your DNA analyzed, looking for genes that may indicate possible trouble ahead. Maybe there's a telltale mutation hiding there or a recognizable pattern of genes.

It is possible now to order up a scan of your genome and see where trouble may lie or may not. Problem is, you might wind up finding more than you bargained for. Your doctor maybe looking, for example, for clues about colon cancer and find an increased risk for breast cancer instead, or Alzheimer's or heart disease.

And at that point is your doctor obligated to tell you about those risks? What if you didn't ask for it, you don't want to know? Is the doc obligated to tell you anyhow? And do you know enough about genome scanning to even know what you want to know? It's not just a patient who might worry about the results. If it's a faulty gene, there's a chance the patient's family members might share the same dangerous mutation. Do you tell them? What is the ethics of that?

The conundrum gets even more complicated. You don't even have to be born yet to get a genetic scan. We're already doing it for fetuses and human embryos produced by in-vitro fertilization. What are parents to make of these test results? Will the results influence their desire to have the baby? Could that knowledge be abused? And where do you go to get genetic counseling anyhow? Are there such genetic specialists?

The ethics of genetic testing and some advice on how to handle it, that's what we're going to be talking about for the rest of the hour. Give us a call. Our number is 1-800-989-8255, 1-800-989-TALK. You can also tweet us, @scifri, S-C-I-F-R-I, or go to our website at sciencefriday.com and join the discussion going on there.

Let me introduce my guests. Hank Greely is law professor at Stanford University in California. He's also director of the Center for Law and Biosciences there. Welcome back to SCIENCE FRIDAY, Dr. Greely.

HANK GREELY: Thanks, Ira, nice to be on the show.

FLATOW: You're welcome. Susan Wolf is a professor of law and medicine at the University of Minnesota in Minneapolis. Welcome to the show.

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Whole Genome Scans Could Reveal Too Much

Space Genome 1st event Interview

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Space Genome 1st event Interview - Video