Category Archives: Genome

15 June 2013 Last updated at 19:20 ET By Tom Heap BBC Countryfile

Scientists have sequenced the genome of a type of ash tree with resistance to the deadly fungal disease sweeping the UK.

The development could be the starting point for breeding a strain of ash to replace thousands expected to succumb to ash die-back in the next few years.

Ash die-back is now established and spreading within Britain

Researchers are hoping that genetics might yield the knowledge to fight back.

A joint project by the John Innes Centre, the Genome Analysis Centre and the Sainsbury Laboratory - all based in Norwich - have reached this milestone just two months after receiving the samples.

Dr Mario Caccamo of the Genome Analysis Centre said: "Speed is important to the research so that all those studying the epidemic can start to look for clues to tackle it."

And they do mean everyone.

All the data is being put on a crowd sourcing website OpenAshDieBack to enable experts from around the world to help identify genes that might be connected to the trees' ability to withstand the fungus.

These genes could then be part of a breeding programme for resistant trees.

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Ash genome reveals fungus resistance

The ruling by the U.S. Supreme Court this week that human genes cannot be patented comes a decade after the Human Genome Project was completed to much fanfare, and people might be forgiven for wondering what the fuss was about. After all, where are the miraculous benefits?

Biotech and drug companies say some are here, and more are on the way. Just as importantly, advances are pushing the technology toward greater affordability. Analysts said Thursday's ruling will help drive costs lower as well.

(Read More: High Court's Ruling on DNA Could Boost Biotech )

"Ten years ago it would've taken a factory full of machines the size of fridge-freezers costing millions of dollars. Now you're talking about doing DNA sequencing on a chip," Life Technologies (LIFE) President Peter Silvester told CNBC's "Squawk Box Europe," showing one little bigger than a Scrabble tile. "The cost is coming down dramatically, and our goal is really to democratize sequencing."

He said that where the mapping of the first human genome took 13 years and $3 billion, five years ago that cost was down to a million, last year it was down to tens of thousands and now it's down to thousands or possibly hundreds of dollars.

The time it takes has been dramatically reduced as well. "Technology, like semiconductor sequencing, can do it in a few hours," he said.

When movie star Angelina Jolie went public about her double mastectomy in May and said she chose that course after genetic testing indicated an 87 percent risk of breast cancer, costs of the gene testing were upwards of $3,000, which may or may not be covered by insurance. However, under Obamacare, genetic counseling and testing must be provided without patient cost-sharing for women whose family history indicates high risk.

Myriad Genetics (MYGN)' stock enjoyed a boost after Jolie disclosed having used the company's cancer-screening services. Thursday's Supreme Court decision was in response to a challenge to Myriad patents.

The mixed ruling, which allowed legal protections for synthetically produced genetic material while disallowing those for naturally occurring genes, sent shares surging more than 10 percent before crashing at the end the day and continuing to fall Friday to close at $27.59, 27 percent off Thursday's high. Investors apparently saw the ruling as opening Myriad's core hereditary testing business to competition.

(Read More: Bristol and Merck Shares Surge on Cancer Drug News )

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Genome Research Benefits Growing, Getting Cheaper

EUKARYOTIC GENOME ORGANIZATION
Uploaded by NTHRYS TEAM http://www.nthrys.com, http://www.nthrys.org.

By: Nthrys Team

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EUKARYOTIC GENOME ORGANIZATION - Video

ChIP-seq analysis using GALAXY: Part 3 - Correlate with genome features using CEAS
This is the third of a series of videos showing how to perform ChIP-seq analysis using a modified version of GALAXY (Golem). Contents: - [start] Introduction...

By: ManchesterBCF

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ChIP-seq analysis using GALAXY: Part 3 - Correlate with genome features using CEAS - Video

Persona 4: The Golden Walkthrough Part 64: Hermit 6, The Genome Project

By: leonyasch

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Persona 4: The Golden Walkthrough Part 64: Hermit 6, The Genome Project - Video

Subaru Legacy 2.0 WR Limited STI Genome Exhaust

By: CTS CaucasTransportSolutions

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Subaru Legacy 2.0 WR Limited STI Genome Exhaust - Video

The Living Genome: Implications and Opportunities for Medicine
Department of Medicine Grand Rounds presentation by Dr. John Stamatoyannopoulos, associate professor of medicine and genome sciences, University of Washingto...

By: UWDeptMedicine

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The Living Genome: Implications and Opportunities for Medicine - Video

Patenting of the Human Genome: Pietro Emiliani at TEDxYouth@DAA
On a daily basis we see this little symbol that stops others from stealing ideas. But what if it wasn #39;t just ideas and intellectual property being copyrigh...

By: TEDxYouth

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Patenting of the Human Genome: Pietro Emiliani at TEDxYouth@DAA - Video

Waldorf Rocket and Genome MIDI Sequencer
Running Waldorf #39;s Rocket Synth using one of my favourite iPad sequencers, Genome.

By: Ashley Elsdon

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Waldorf Rocket and Genome MIDI Sequencer - Video

A bit of automation with Genome and the Waldorf Rocket

By: Ashley Elsdon

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A bit of automation with Genome and the Waldorf Rocket - Video