Category Archives: Genome

Dynamic Genome Playlist Introduction
Dynamic Genome Playlist introduction The genome changes its look: 1. From static to dynamic 2. From closed to open 3. From simple to complex 4. From random t...

By: Gershom Zajicek M.D,

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Dynamic Genome Playlist Introduction - Video

22 September 2013 Last updated at 19:33 ET By Helen Briggs BBC News

UK scientists have mapped the genome of the British ash tree, in research to find a way to protect woodlands from a deadly fungus.

The data has been released on the internet for use by the global scientific community.

The ash tree genome map is the latest advance in fighting Chalara, which causes ash dieback.

According to new figures, ash dieback is spreading rapidly in Britain and has been found in more than 200 woods.

Evidence from continental Europe suggests that as many as 90% of ash trees could eventually die from the infection.

Scientists are searching for genetic clues to why some trees appear to be able to survive.

A team at Queen Mary University of London, has mapped the genome of a native ash tree for the first time, as part of the research.

The tree came from a wood in Gloucestershire owned by the Earth Trust.

Dr Richard Buggs of Queen Mary University of London, said it was a big leap forward.

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Scientists map UK ash tree genome

Entire human genome gets broken down in SA
For more on this and other stories please visit http://www.enca.com/ Johannesburg, September 18 -- In a first for Africa, the entire human genome has been br...

By: eNCAnews

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Entire human genome gets broken down in SA - Video

"Genome Kid"
song written performed by H Watnik @2013.

By: Harry Watnik

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"Genome Kid" - Video

For decades, we as a culture have referred to a persons genome as a singular thing a set of DNA that exists in each cell and is unique to each person. You are a person and you have one genome.

But the New York Times this week brought to light mounting evidence that thats not necessarily true. It introduced to the masses two terms that have been gaining acceptance among scientists over the past several years: chimerism and mosaicism.

Both reflect the notion that an individual can have more than one genome. A twin, for example, might acquire some of the other twins blood cells in the womb, and end up with part of his genome. A woman can apparently gain genomes from fetal cells left behind after she gives birth to a baby. People who have bone marrow transplants, too, have been shown in studies to end up with some of their donors genomes.

What does this finding mean for medicine? The U.S. government undertook the $3 billion Human Genome Project more than two decades ago to improve DNA sequencing, which would help scientists better understand disease. Since then, a number of diagnostic tests and gene therapies have been developed for cancers and rare diseases based on the idea that a persons genome represents his genetic makeup.

Now, according to Carl Zimmer in the Times:

Scientists are finding links from multiple genomes to certain rare diseases, and now theyre beginning to investigate genetic variations to shed light on more common disorders.

Sciences changing view is also raising questions about how forensic scientists should use DNA evidence to identify people. Its also posing challenges for genetic counselors, who cant assume that the genetic information from one cell can tell them about the DNA throughout a persons body.

In other words, the complicated science of the human genome just got more complicated. Maybe, after all, a cheek swab wont reveal as much about a persons health as we once thought.

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Wow of the Week: Scientists challenge the idea of the individual genome

Published: Sept. 20, 2013 at 4:33 PM

BEIJING, Sept. 20 (UPI) -- Comparison of the genome of a Siberian tiger with those of other big cats provides a resource to study big cats' conservation, South Korean researchers said.

Researchers with South Korea's Personal Genomics Institute sequenced the whole genome of an Amur, or Siberian, tiger, assembled by using software tools, Chinese genomic-affiliated BGI said Friday in a release.

Among other things, the researchers learned the Siberian tiger displayed more than 95 percent similarity to the genome of the domestic cat.

Researchers also sequenced the genomes of a white Bengal tiger, an African lion, a white African lion and a snow leopard, using advanced sequencing technology, and aligned them using the tiger and domestic cat genome sequences, BGI said.

They found a number of Panthera lineage-specific and felid-specific amino acid changes that they said could affect the metabolism pathways of carnivores.

The researchers discovered evidence that genes related to muscle strength, energy metabolism and sensory nerves appeared to be undergoing rapid evolution in the tiger, which could help in conservation efforts, BGI said.

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Tiger, lion and leopard genomes could aid in big cats' conservation

Data Sharing and the HeLa Genome Sequence - Kathy Hudson
September 9, 2013 - National Advisory Council for Human Genome More: http://www.genome.gov/27554864.

By: GenomeTV

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Data Sharing and the HeLa Genome Sequence - Kathy Hudson - Video

Chinese scientists complete wheat genome A -amp D drawings 2013 News
Chinese scientists complete wheat genome A -amp D drawings.

By: tanzani trefic

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Chinese scientists complete wheat genome A -amp D drawings 2013 News - Video

The NHGRI-Smithsonian Genome Exhibition - Vence Bonham
September 9, 2013 - National Advisory Council for Human Genome More: http://www.genome.gov/27554864.

By: GenomeTV

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The NHGRI-Smithsonian Genome Exhibition - Vence Bonham - Video

NEW YORK, Sept. 19, 2013 /PRNewswire/ --The New York Genome Center (NYGC) officially launched its scientific and clinical consortium of academic and industry leaders focused on harnessing genomics to advance the understanding and treatment of disease. The announcement was made at the start of NYGC's inaugural scientific symposium with New York City Mayor Michael Bloomberg speaking at a ribbon cutting ceremony.

The two-day scientific symposium kicks off the opening of NYGC's new 170,000 square foot research facility in Manhattan and brings together leaders of 16 member institutions to discuss the importance of genomics research for the detection, diagnosis, and treatment of human disease.

The symposium features a number of prominent speakers, including Dr. Harold Varmus, Director of the National Cancer Institute, Marc Tessier-Lavigne, President of The Rockefeller University, Nobel Laureate Dr. James Watson, Cold Spring Harbor Laboratory, and Dr. Tom Maniatis, Chairman of the Department of Biochemistry and Molecular Biophysics at Columbia University and Chair of NYGC's Scientific and Clinical Steering Committee, as well as panelists discussing Pharmacogenomics, Genomics, Quantified Health, and the Future of Big Data on Patient Care.

"The opening of the New York Genome Center is a major achievement in the City's ongoing efforts to advance the bioscience sector in New York City part of our commitment to diversify the city's economy and create jobs," said Mayor Bloomberg. "The Genome Center's new facility and its groundbreaking approach to collaboration will help solve some of medicine's most challenging problems by bringing together the city's best academic and clinical institutions."

"We applaud Mayor Bloomberg's longstanding support and unwavering commitment to the technology and science community here in New York City," said Dr. Robert Darnell, President and Scientific Director of NYGC. "Modern genomics has the power to transform medicine. NYGC will provide the leadership to change the standard of care of patients from day one. This new facility represents the intersection of the clinic and the lab--translational science. As a physician-scientist, I recognize the importance of uniting these two worlds. The collaboration we've formed with our member institutions will not simply just do great science but will work to save lives."

"Collaboration is essential for solving the most complex and difficult problems in biomedical science," said Dr. Tom Maniatis, Chair of NYGC's Scientific and Clinical Steering Committee. "I have been involved from the beginning in a city-wide effort to create a consortium that effectively marshals the resources, identifies the critical questions, and creates the environment to tackle problems that are too big for individual researchers or institutions to solve alone. By bringing together some of the best minds in science and the intellectual diversity represented in New York into the NYGC consortium, we believe that we can push forward the boundaries of biomedical science in an unprecedented manner."

"No other city in the world has the breadth of scientific talent, healthcare delivery systems, and demographically diverse population that can be found in New York," said Russ Carson, Co-Chair of NYGC's Board of Directors. "The New York Genome Center will be a catalyst to promote greater interaction and collaboration among the City's premier institutions and scientists by integrating basic research, diagnosis, and clinical care. Collectively this consortium has the potential to effectively change the paradigm in medicine by incorporating genomics across the spectrum of their activities."

About the New York Genome Center

The New York Genome Center (NYGC) is an independent non-profit organization that leverages the collaborative resources of leading academic medical centers, research universities, as well as pharmaceutical, biotech, and technology companies. The vision of NYGC is to transform medical research and clinical care in New York and beyond through the creation of one of the largest genomics research facilities in North America, integrating sequencing, bioinformatics, data management, and genomics research.

NYGC represents an unprecedented sharing of data and resources among premier institutions, which will dramatically increase the quality and speed of research outcomes to advance clinical care. The collaborative power of NYGC's members will help nurture scientific advances leading to accelerate the development of new diagnostics and treatments for human diseases, and provide an engine for life science commercialization in the region.

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New York Genome Center Launches Groundbreaking Consortium to Accelerate Scientific and Clinical Discoveries