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Category Archives: Genetic Engineering

Should we be concerned with synthetic biology?

Posted: March 9, 2014 at 2:44 pm

Dear EarthTalk: Should those of us who care about our health and the planet be concerned about the new trend in genetic engineering called synthetic biology? Chrissie Wilkins, Bern, N.C.

Synthetic biology (or synbio) refers to the design and fabrication of novel biological parts, devices and systems that do not otherwise occur in nature. Many see it as an extreme version of genetic engineering (GE). But unlike GE, whereby genetic information with certain desirable traits is inserted from one organism into another, synbio uses computers and chemicals to create entirely new organisms.

Proponents of synbio, which include familiar players such as Cargill, BP, Chevron and Du Pont, tout its potential benefits. According to the Synthetic Biology Engineering Research Center (SYNBERC), a consortium of leading U.S. researchers in the field, some promising applications of synthetic biology include alternatives to rubber for tires, tumor-seeking microbes for treating cancer, and photosynthetic energy systems. Other potential applications include using synbio to detect and remove environmental contaminants, monitor and respond to disease and develop new drugs and vaccines.

While these and other applications may not be widely available for years, synthetic biology is already in use for creating food additives that will start to show up in products on grocery shelves later this year. Switzerland-based Evolva is using synthetic biology techniques to produce alternatives to resveratrol, stevia, saffron and vanilla. The companys synthetic vanillin is slated to go into many foods as a cheaper and limitless version of real vanilla flavor. But many health advocates are outraged that such a product will be available to consumers without more research into potential dangers and without any warnings or labeling to let consumers know they are eating organisms designed and brought to life in a lab.

This is the first major use of a synbio ingredient in food, and dozens of other flavors and food additives are in the pipeline, so synbio vanilla could set a dangerous precedent for synthetic genetically engineered ingredients to sneak into our food supply and be labeled as natural, reports Friends of the Earth (FoE), a leading environmental group. Synthetic biology vanillin poses several human health, environmental and economic concerns for consumers, food companies and other stakeholders.

For example, FoE worries that synbio vanilla (and eventually other synthetic biology additives) could exacerbate rainforest destruction while harming sustainable farmers and poor communities around the world. Synbio vanillacould displace the demand for the natural vanilla market, reports FoE. Without the natural vanilla market adding economic value to the rainforest in these regions, these last standing rainforests will not be protected from competing agricultural markets such as soy, palm oil and sugar. Critics of synbio also worry that releasing synthetic life into the environment, whether done intentionally or accidentally, could have adverse effects on our ecosystems.

Despite these risks, could the rewards of embracing synthetic biology be great? Could it help us deal with some of the tough issues of climate change, pollution and world hunger? Given that the genie is already out of the bottle, perhaps only time will tell.

EarthTalk is written and edited by Roddy Scheer and Doug Moss and is a registered trademark of E-The Environmental Magazine http://www.emagazine.com. Send questions to: earthtalk@emagazine.com.

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Infomercial 3: Genetic Engineering – Video

Posted: March 8, 2014 at 9:47 pm


Infomercial 3: Genetic Engineering
Mrs Marsha, 3rd period, infomercial #3.

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EarthTalk / Synthetic vanilla may be just first of many 'synbio' additives

Posted: March 7, 2014 at 8:45 am

Dear EarthTalk: Should those of us who care about our health and the planet be concerned about the new trend in genetic engineering called synthetic biology?

Chrissie Wilkins

New Bern, N.C.

"Synthetic biology" (or "synbio") refers to the design and fabrication of novel biological parts, devices and systems that do not otherwise occur in nature. Many see it as an extreme version of genetic engineering. But unlike genetic engineering, whereby genetic information with certain desirable traits is inserted from one organism into another, synbio uses computers and chemicals to create entirely new organisms.

Proponents of synbio -- which include familiar players such as Cargill, BP, Chevron and DuPont -- tout its potential benefits. According to the Synthetic Biology Engineering Research Center, a consortium of leading U.S. researchers in the field, some promising applications of synthetic biology include alternatives to rubber for tires, tumor-seeking microbes for treating cancer, and photosynthetic energy systems. Other potential applications include using synbio to detect and remove environmental contaminants, monitor and respond to disease and develop new drugs and vaccines.

While these and other applications may not be widely available for years, synthetic biology is already in use for creating food additives that will start to show up in products on grocery shelves later this year. Switzerland-based Evolva is using synthetic biology techniques to produce alternatives to resveratrol, stevia, saffron and vanilla. The company's "synthetic vanillin" is slated to go into many foods as a cheaper and limitless version of real vanilla flavor. But many health advocates are outraged that such a product will be available to consumers without more research into potential dangers and without any warnings or labeling to let consumers know they are eating organisms designed and brought to life in a lab.

"This is the first major use of a synbio ingredient in food, and dozens of other flavors and food additives are in the pipeline, so synbio vanilla could set a dangerous precedent for synthetic genetically engineered ingredients to sneak into our food supply and be labeled as `natural,' " reports Friends of the Earth, a leading environmental group. "Synthetic biology vanillin poses several human health, environmental and economic concerns for consumers, food companies and other stakeholders."

For example, FoE worries that synbio vanilla (and eventually other synthetic biology additives) could exacerbate rainforest destruction while harming sustainable farmers and poor communities around the world. "Synbio vanilla ... could displace the demand for the natural vanilla market," reports FoE. "Without the natural vanilla market adding economic value to the rainforest in these regions, these last standing rainforests will not be protected from competing agricultural markets such as soy, palm oil and sugar." Critics of synbio also worry that releasing synthetic life into the environment, whether done intentionally or accidentally, could have adverse effects on our ecosystems.

Despite these risks, could the rewards of embracing synthetic biology be great? Could it help us deal with some of the tough issues of climate change, pollution and world hunger? Given that the genie is already out of the bottle, perhaps only time will tell.

EarthTalk is by Roddy Scheer and Doug Moss of E -- The Environmental Magazine (www.emagazine.com). Send questions to earthtalk@emagazine.com.

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Cloned Human Embryos As Well As Animal Human Hybrids? – Video

Posted: March 6, 2014 at 7:44 am


Cloned Human Embryos As Well As Animal Human Hybrids?
abominationFebruary 2014 Breaking News Labs Mixing Human DNA with Animal DNA 1 of 5 Last days final hour news prophecy update 2 of 4 ... 3 of 4 ... 4 of 4 .....

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Can low-dose interferon prevent relapse of hepatitis C virus infection?

Posted: at 7:44 am

PUBLIC RELEASE DATE:

5-Mar-2014

Contact: Vicki Cohn vcohn@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, March 5, 2014Chronic hepatitis C virus (HCV) infection can lead to serious diseases such as cirrhosis and cancer of the liver, so viral clearance and prevention of relapse are important treatment goals. Low-dose oral interferon may reduce the risk of HCV relapse in patients with mild liver fibrosis according to a study published in Journal of Interferon & Cytokine Research, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers. The article is available free on the Journal of Interferon & Cytokine Research website.

In "A Double-Blind Randomized Controlled Study to Evaluate the Efficacy of Low-Dose Oral Interferon-Alpha in Preventing Hepatitis C Relapse," Chuan-Mo Lee and coauthors from several universities and hospitals in Taiwan present the results of a clinical trial comparing the effects of 24 weeks of treatment with two doses of oral interferon-alpha or placebo in patients who achieved viral clearance after successful HCV therapy.

"This is a highly significant study relevant to the optimal use of IFN for HCV treatment," says Co-Editor-in-Chief Ganes C. Sen, PhD, Chairman, Department of Molecular Genetics, Cleveland Clinic Foundation, Ohio.

###

About the Journal

Journal of Interferon & Cytokine Research (JICR), led by Co-Editors-in-Chief Ganes C. Sen, PhD, and Thomas A. Hamilton, PhD, Chairman, Department of Immunology, Cleveland Clinic Foundation, is an authoritative peer-reviewed journal published monthly online with Open Access options and in print that covers all aspects of interferons and cytokines from basic science to clinical applications. JICR is an official journal of the International Cytokine and Interferon Society. Complete tables of content and a sample issue may be viewed online on the Journal of Interferon & Cytokine Research website.

About the Publisher

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Genetic engineering talk show – Video

Posted: March 4, 2014 at 8:43 pm


Genetic engineering talk show

By: Victor Rodriguez

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Genetic engineering talk show - Video

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Which interventions are most effective to promote exclusive breastfeeding?

Posted: at 8:43 pm

PUBLIC RELEASE DATE:

4-Mar-2014

Contact: Vicki Cohn vcohn@liebertpub.com 914-710-2100 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, March 4, 2014Only about 37% of babies around the world are exclusively breastfed for the first 6 months of life, as recommended by the World Health Organization (WHO). The benefits of breastfeeding for both infants and mothers are well-established. The effectiveness of different types of interventions for promoting exclusive breastfeeding in high-income countries is the focus of a Review article published in Breastfeeding Medicine, the official journal of the Academy of Breastfeeding Medicine published by Mary Ann Liebert, Inc., publishers. The article is available free on the Breastfeeding Medicine website at http://www.liebertpub.com/bfm.

Most interventions designed to encourage women to breastfeed use supportive or educational approaches, with varying levels of success, according to study authors Helen Skouteris and colleagues from Deakin University and University of Melbourne (Melbourne, Australia), and Leeds Metropolitan University (Leeds, UK).

In the article "Interventions Designed to Promote Exclusive Breastfeeding in High-Income Countries: A Systematic Review" the authors evaluate the effectiveness of different interventions, comparing prenatal and postnatal approaches, the duration of the interventions, and identify whether they focus on educating mothers or providing emotional support.

"The search for successful interventions that promote the international goal of exclusive breastfeeding for the first six months of an infant's life has been continual but inconclusive," says Ruth Lawrence, MD, Editor-in-Chief of Breastfeeding Medicine and Professor of Pediatrics, University of Rochester School of Medicine. "Authors Helen Skouteris and colleagues in their extensive review point out that a trial of more support and interventions in the postpartum period may be critical to solving this issue."

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About the Journal

Breastfeeding Medicine, the Official Journal of the Academy of Breastfeeding Medicine, is an authoritative, peer-reviewed, multidisciplinary journal published 10 times per year in print and online. The Journal publishes original scientific papers, reviews, and case studies on a broad spectrum of topics in lactation medicine. It presents evidence-based research advances and explores the immediate and long-term outcomes of breastfeeding, including the epidemiologic, physiologic, and psychological benefits of breastfeeding. Tables of content and a sample issue may be viewed on the Breastfeeding Medicine website at http://www.liebertpub.com/bfm.

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Commentary: field of tissue engineering is progressing at remarkable pace

Posted: at 8:43 pm

What many didnt realise was that the freaky looking ear was never grown, had nothing to do with genetic engineering and wasnt really a scientific breakthrough at all! Instead, it served as the publics introduction to the new field of tissue engineering, through which researchers attempt to create replacement tissues in the laboratory by combining resorbable materials with stem cells.

Tissue engineers, like those in my laboratory at Kings College London, work to build everything from cartilage to fix creaky arthritic knees to coronary arteries to patch up heart patients. What looked like a human ear grown on a mouse was simply what we call a scaffold, an implantable 3D structure made of a plastic that safely dissolves in the body.

Twenty years later, a UCL-based team led by Dr Patrizia Ferretti is continuing to build on this work to reconstruct ears. Surgeons currently treat microtia, a condition in which children are born with a malformed or missing ear, by taking cartilage from the patients rib and implanting it in the head to form something that looks like an ear.

Dr Ferretti hopes to eliminate the need for this second cartilage-harvesting surgery by growing ear cartilage in the laboratory.

The difference here is that whereas in the 1990s tissue engineers thought that merely forming a scaffold of the correct shape and size would allow us to create a tissue, we now understand that a stem cells perception of its nano-environment plays an important role in determining the tissue it creates.

In short, we can now tailor a scaffold with nano-cues that tell a stem cell to become a liver cell instead of lung.

Dr Ferrettis scaffold does just this. Her team utilises a new nanocaged POSS-PCU scaffold to coax stem cells collected from fat to form cartilage whilst the scaffold slowly melts away.

This exciting material came to light in 2011 when it was used to replace the windpipe of a patient who had to have his own removed because of cancer.

The scaffold here instructed stem cells to create the windpipes lining, essentially using the body as an incubator to help direct their fate. This time, the UCL team utilised a cocktail of chemicals to help push the stem cells to make cartilage, so it remains to be seen if the scaffold will similarly drive ear cartilage formation once placed in the body.

What is clear, however, is that the field of tissue engineering is progressing at a remarkable pace and tailor-made tissues to treat a range of conditions are a real possibility in the near future."

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Commentary: field of tissue engineering is progressing at remarkable pace

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Meeting face to face vs. meeting on Facebook — new study on social anxiety

Posted: at 8:43 pm

PUBLIC RELEASE DATE:

4-Mar-2014

Contact: Vicki Cohn vcohn@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, March 4, 2014Nearly a billion people use Facebook, the largest social networking site, but interacting with someone on social media is not the same as meeting them in person. The results of a study to determine whether Facebook exposure increases or reduces arousal during initial face-to-face encounters, especially among socially anxious individuals, are presented in Cyberpsychology, Behavior, and Social Networking, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Cyberpsychology, Behavior, and Social Networking website.

"Face to Face Versus Facebook: Does Exposure to Social Networking Web Sites Augment or Attenuate Physiological Arousal Among the Socially Anxious?" Shannon Rauch and colleagues, Benedictine University at Mesa, AZ and Providence College, RI, evaluated the study participants for their level of social anxiety and then exposed each of them to a person via Facebook, a face-to-face encounter, or both. During the exposures the researchers measured physiological arousal using the galvanic skin response measure.

"Results appear to indicate that initial exposure to an individual via Facebook may have a negative impact on consequent face-to-face encounters with that individual for those with high social anxiety," says Brenda K. Wiederhold, PhD, MBA, BCB, BCN, Editor-in-Chief of Cyberpsychology, Behavior, and Social Networking, from the Interactive Media Institute, San Diego, CA.

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About the Journal

Cyberpsychology, Behavior, and Social Networking is a peer-reviewed journal published monthly online with Open Access option and in print that explores the psychological and social issues surrounding the Internet and interactive technologies, plus cybertherapy and rehabilitation. Complete tables of content and a sample issue may be viewed on the Cyberpsychology, Behavior, and Social Networking website.

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EarthTalk: What is Synthetic Biology?

Posted: March 3, 2014 at 11:43 pm

Westport, CT - infoZine - E/The Environmental Magazine - "Synthetic biology" (or "synbio") refers to the design and fabrication of novel biological parts, devices and systems that do not otherwise occur in nature. Many see it as an extreme version of genetic engineering (GE). But unlike GE, whereby genetic information with certain desirable traits is inserted from one organism into another, synbio uses computers and chemicals to create entirely new organisms.

Proponents of synbio, which include familiar players such as Cargill, BP, Chevron and Du Pont, tout its potential benefits. According to the Synthetic Biology Engineering Research Center (SYNBERC), a consortium of leading U.S. researchers in the field, some promising applications of synthetic biology include alternatives to rubber for tires, tumor-seeking microbes for treating cancer, and photosynthetic energy systems. Other potential applications include using synbio to detect and remove environmental contaminants, monitor and respond to disease and develop new drugs and vaccines.

"This is the first major use of a synbio ingredient in food, and dozens of other flavors and food additives are in the pipeline, so synbio vanilla could set a dangerous precedent for synthetic genetically engineered ingredients to sneak into our food supply and be labeled as natural," reports Friends of the Earth (FoE), a leading environmental group. "Synthetic biology vanillin poses several human health, environmental and economic concerns for consumers, food companies and other stakeholders."

For example, FoE worries that synbio vanilla (and eventually other synthetic biology additives) could exacerbate rainforest destruction while harming sustainable farmers and poor communities around the world. "Synbio vanillacould displace the demand for the natural vanilla market," reports FoE. "Without the natural vanilla market adding economic value to the rainforest in these regions, these last standing rainforests will not be protected from competing agricultural markets such as soy, palm oil and sugar." Critics of synbio also worry that releasing synthetic life into the environment, whether done intentionally or accidentally, could have adverse effects on our ecosystems.

Despite these risks, could the rewards of embracing synthetic biology be great? Could it help us deal with some of the tough issues of climate change, pollution and world hunger? Given that the genie is already out of the bottle, perhaps only time will tell.

Related Links SYNBERC: http://www.synberc.org FoE: http://www.foe.org Evolva: http://www.evolva.com

Send your environmental questions to: EarthTalk, c/o E - The Environmental Magazine, P.O. Box 5098, Westport, CT 06881;

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