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Category Archives: Eczema
Atopic dermatitis | American Academy of Dermatology
Posted: August 2, 2016 at 4:30 pm
Atopic dermatitis (AD) looks different in infants, children, and adults. The following gives you the signs (what you see) and symptoms (what you feel) for each age group.
AD can begin early. A child may be 2 or 3 months old when AD begins. When AD begins early, it often causes:
Parents often worry that their babies are getting AD in the diaper area. A babies rarely gets AD in his or her diaper area. The skin stays too moist for AD.
In time, the skin with AD can:
The thickened skin can itch even when the AD is not flaring.
When talking about the thickened skin, your dermatologist may use the word lichenification. This word means thickened skin.
It is rare for adults to get AD. Most people (90%) get AD before age 5. About half (50%) of people who get AD during childhood continue to have milder signs and symptoms of AD as an adult. When an adult has AD, it often looks different from the AD of childhood. For adults, AD often:
If a person has had AD for years, patches of skin may be thick and darker than the rest of the skin (or lighter). Thickened skin can itch all the time.
Adults who had AD as a child and no longer have AD can have the following:
Images used with permission of the American Academy of Dermatology National Library of Dermatologic Teaching Slides
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Atopic dermatitis | American Academy of Dermatology
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Eczema, Causes, Tests, Diagnosis & Treatment
Posted: at 4:30 pm
Have you ever had a red, itchy rash that does not go away? Chances are, it may be eczema. While mild eczema is not life threatening, it may be extremely uncomfortable with an itch. Symptoms usually vary depending on the individual, and may include dry, scaly, red and itchy skin. If left untreated, constant scratching may lead to bleeding, crusting, or broken skin open to possible infection. It is usually easily diagnosed by doctors by a physical check-up, and most of the time, does not require biopsies or additional testing.
According to the National Eczema Association, the term "eczema" is a general term used to describe dermatitis and can be interchangeably used. Although it comes in many forms, eczema mostly describes a dry skin condition that may be relieved by moisturizers and emollients. This skin condition is not contagious, so you cannot pass it on to other people or catch them from someone else.
A specific cause for eczema has yet to be identified. Many believe that this skin condition is attributed to a combination of factors that include:
Many of these factors are still speculation, with further research needed to confirm a specific cause for eczema. Factors like asthma and hay fever that are often associated with eczema could pose as possible leads. However, not all people who have been diagnosed with eczema have shown these particular medical conditions.
Since eczema can refer to various types of irritated skin, the types can almost be endless. Here are some of the more common types of eczema:
The most common symptom of eczema is red, swollen and itchy skin. The symptoms may vary depending on the specific type of eczema you are dealing with. Blisters and scaly patches are also possible symptoms of eczema. These blisters might also ooze, crust and even bleed. Skin color may also change, and can even become thick and leathery. These outbreaks can appear practically anywhere on the body, and the location of the affected area can be used to classify the particular type of eczema that the person is suffering from.
Unfortunately, there is no known treatment for eczema, but there are many ways to relieve symptoms. For example, there are several easy home remedies that can help relieve itch and irritation should a breakout take place.
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Eczema, Causes, Tests, Diagnosis & Treatment
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Compare 182 Eczema Medications | Drugs.com
Posted: at 4:30 pm
Generic name:hydrocortisone topical
Brand names: Cortizone-10, Westcort, Anucort-HC, Locoid Lipocream, Locoid, Proctozone HC, Hytone, Proctosol-HC, Hydrocortisone with Aloe, Beta HC, Cortaid, Proctocort, Ala-Cort, Ala-Scalp, Ala-Scalp HP, Anumed-HC, Aqua Glycolic HC, Aquanil HC, Bioelements Immediate Comfort, Caldecort, Cetacort, Cortaid Maximum Strength, Corticaine, Cortizone-5, Cortizone-10 Anal Itch Cream, Cotacort, Dermarest Plus Anti-Itch, Dermasorb HC, Dermtex HC, Gly-Cort, Gynecort Maximum Strength, Hemorrhoidal HC, Hemril-30, Hemril-HC Uniserts, Instacort, Itch-X Lotion, Keratol HC, Lacticare-HC, Nutracort, Pandel, Pediaderm HC, Procto-Kit 1%, Procto-Kit 2.5%, Procto-Med HC, Procto-Pak 1%, ProctoCare-HC, Proctocream-HC, Proctosert HC, Proctozone-H, Recort Plus, Rectasol-HC, Sarnol-HC, Scalacort, Scalp-Cort, Scalpicin, Texacort, U-Cort
Drug class: topical steroids
For consumers: dosage, interactions, side effects
For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information
Generic name:triamcinolone topical
Brand names: Kenalog, Aristocort A, Aristocort R, Cinolar, DermacinRx Silazone, Dermasorb TA, Oralone, Pediaderm TA, Triacet, Trianex, Triderm
Drug class: topical steroids
For consumers: dosage, interactions, side effects
For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information
Generic name:clobetasol topical
Brand names: Clobevate, Clobex, Clodan, Cormax, Cormax Scalp, Dermovate, Embeline, Embeline E, Olux, Olux-E, Olux / Olux-E Kit, Temovate, Temovate E
Drug class: topical steroids
For consumers: dosage, interactions, side effects
For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information
Generic name:dexamethasone systemic
Brand names: Dexamethasone Intensol, Decadron, Baycadron, Dexpak Taperpak, De-Sone LA, Dexacen-4, Dexasone, Dexasone LA, Solurex, Solurex LA, Zema Pak
Drug class: glucocorticoids
For consumers: dosage, interactions, side effects
For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information
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Compare 182 Eczema Medications | Drugs.com
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Types of Eczema : National Eczema Society
Posted: at 4:30 pm
Information and advice on the different types of eczema from atopic to varicose.
The term atopic refers to a personal and family tendency to develop eczema, asthma and/or hay fever.
Contact dermatitis is the most common type of work related skin disease.
Seborrhoeic dermatitis in adults tends to affect the scalp, face, torso and flexures.
Infantile seborrhoeic dermatitis (also called seborrhoeic eczema) is a common skin condition seen in infants under the age of one year. Often, but not always it affects the scalp as cradle cap.
Discoid eczema is very distinct with coin shaped discs of eczema the size of a fifty pence piece.
The key characteristic of pompholyx eczema is blistering that is restricted to the hands and feet.
Also known as eczema cracquele, Asteatotic eczema almost always affects people over the age of 60.
Varicose eczema (also called gravitational or stasis eczema) is common later in life.
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Types of Eczema : National Eczema Society
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Eczema Causes and Risks: Genetics, Environment, and More
Posted: July 31, 2016 at 5:42 am
Doctors don't know exactly what causes eczema. The most common type of eczema -- atopic dermatitis -- resembles an allergy. But the skin irritation, which is more often seen in children rather than adults, is not an allergic reaction.
The current thinking is that eczema is caused by a combination of factors that include:
Here's more detail on what's known about eczema causes:
Eczema is not contagious. You or your children can't catch eczema by coming in contact with someone who has it.
Eczema runs in families. That suggests a genetic role in eczema's development. A major risk factor is having relatives who have or had:
Doctors also know that a large percentage of children with severe eczema will later develop asthma or other allergies.
Mother's age at time of birth. It's isn't clear why, but children born to older women are more likely to develop eczema than children born to younger women.
Role of environment. Children are more likely to develop eczema if they:
Eczema is not an allergic reaction. Even so, a large number of children who have eczema also have food allergies. That doesn't mean that certain foods such as dairy, eggs, and nuts -- common food allergy triggers in children with eczema -- cause it or make it worse. Before removing particular foods from your child's diet, talk with your health care provider to be sure your child's nutritional needs will be met.
A trigger is not something that causes eczema. But it can cause it to flare or make a flare worse.
The most common triggers are substances that irritate the skin. For instance, in many people with eczema, wool or man-made fibers that come in contact with the skin can trigger a flare.
Examples of other things that can irritate the skin include:
Flares can also be triggered by certain conditions that have an effect on the immune system. For instance, things that can trigger or worsen a flare include:
Stress has also been identified as a possible trigger.
Actions and environments that cause the skin to dry out or become otherwise sensitive can trigger flares. Some examples include:
SOURCES:
MedicineNet.com: "Eczema."
KidsHealth.org: "Eczema."
National Institute of Arthritis and Musculoskeletal and Skin Diseases: "What Is Atopic Dermatitis?"
American Academy of Dermatology: "Atopic dermatitis: Who gets and causes."
MedlinePlus: "Atopic eczema."
American Academy of Dermatology: "What is Eczema?"
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Eczema Causes and Risks: Genetics, Environment, and More
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Eczema Guide: Causes, Symptoms and Treatment Options
Posted: July 25, 2016 at 3:43 pm
What Is It?
Dermatitis is a skin inflammation. Eczema is the most common type of dermatitis.
Eczema first appears as an episode of itching and redness of the skin. You also may have tiny bumps or blisters.
When eczema develops into a long-term condition, it is called chronic eczema. This leads to:
Thickening of the skin
Scaling
Flaking
Dryness
Color changes
There are many types of eczema. The type depends on the cause, shape and location of the rash.
Most eczemas are related to allergies or to contact with irritating substances. Some are associated with fluid retention in the legs.
Following are types of eczema:
Atopic eczema (atopic dermatitis) This type of eczema comes and goes repeatedly. It usually occurs in people with an inherited tendency to allergies. These allergies may include allergic asthma, hay fever or food allergies.
Atopic eczema appears early in life, usually by 18 months. In babies, atopic eczema primarily affects the:
Atopic eczema in older children, teenagers and adults usually involves the:
Contact dermatitis When irritants touch the skin, they can produce two types of contact dermatitis. Irritant contact dermatitis is the direct irritation of the skin. It can be caused by prolonged contact with irritants such as:
Detergents
Bubble bath
Harsh soap
Sweat
Saliva
Urine
The second type of contact dermatitis is allergic contact dermatitis. This is an allergic reaction in the skin. This type occurs in people who have an allergy to a specific substance. The most common allergens are poison ivy, poison oak and poison sumac.
Other substances that can trigger skin allergies include:
Some building materials
Cleaning products
Deodorants
Cosmetics
Medications
Nickel in earrings
Chemicals in:
Fragrances
Skin cream and lotions
Shampoos
Shoes
Clothing
Hand eczema Hand eczema is limited to the hands. It can be related to atopic eczema. Or it can result from repeated hand washing or exposure to strong detergents. Occasionally, it is caused by an allergy, such as to latex.
Nummular eczema This eczema causes coin sized patches of irritated skin. It typically appears on the legs, arms or chest. It usually occurs in adults. It can be related to atopic dermatitis and, less often, allergic contact dermatitis.
Sometimes, it is an allergic reaction to a fungal infection such as athlete's foot. It still appears on the arms, legs or chest, even if the fungal infection is elsewhere on the body.
Asteatotic eczema This eczema dries the skin, causing fine cracks. It often first involves the lower legs. It commonly occurs in the elderly. It is common during winter months spent indoors in low humidity environments.
Stasis dermatitis This type appears on the calves, ankles and feet. It occurs in people who have poorly functioning veins in the lower legs. The veins cause blood to collect in the legs (stasis). This leads to leg swelling, which leads to the signs of stasis dermatitis:
Lichen simplex chronicus This eczema is a reaction to repeated scratching or rubbing of the skin. A nervous scratching habit can lead to thickened, discolored skin. Skin picking can lead to smaller bumps of the same type of rash.
Seborrheic dermatitis This type creates a greasier rash than usual for eczema. This scaly dermatitis commonly appears on the scalp of infants (as cradle cap). In adults, it appears as dandruff. It commonly affects the face or neck around the nose and at the scalp line.
Short-term symptoms of eczema include itchy skin, redness and tiny bumps or blisters.
If these symptoms remain untreated, the skin can become thick, scaly and dry. There can be areas of hair loss and color changes. Skin affected by long-term eczema is more vulnerable to secondary infections.
Each type of eczema has specific characteristics and patterns of symptoms:
Atopic eczema (atopic dermatitis) Atopic dermatitis appears as irritated, red, dry, crusted patches on the skin. If the skin becomes infected, it may develop a wet (weeping) look. Scratching the itchy patches causes more irritation. It increases the risk of infection.
Contact dermatitis When an irritant causes contact dermatitis, symptoms can range from a mild redness to severe skin blistering or ulceration.
When triggered by an allergic reaction, it usually causes skin redness, fine red bumps or blisters and severe itching.
A reaction caused by plant allergies (like poison ivy or poison oak) is usually intense. It appears as bumps and blisters in lines or streaks where the plant brushed against the skin.
Hand eczema Hand eczema usually appears during the winter as patches of dry, cracked skin. There may or may not be redness. Hand eczema may also cause itching, red bumps or blisters and scaling. Irritation often occurs under rings from soap trapped under the rings.
Nummular eczema Nummular eczema begins as small areas of irritation. They turn into round red, crusted or scaly patches.
Asteatotic eczema This type usually occurs on the lower legs. It causes itching or stinging pain in areas of dry, cracked, reddened skin. There may or may not be tiny bumps.
Stasis dermatitis Stasis dermatitis occurs in legs that are already puffy or swollen. It usually begins with mild redness and itching of the lower legs. If redness and tenderness develop suddenly, it could be caused by a secondary bacterial infection. Bacterial infections require immediate medical attention.
Lichen simplex chronicus This rash creates thickened, leathery skin with darkening of skin color. It is very itchy. Scratching makes the problem worse.
Seborrheic dermatitis Seborrheic dermatitis causes red, scaly patches with yellow, greasy crusts. These patches can be itchy or can cause burning.
Patches appear most commonly on the scalp as dandruff. But they also can occur elsewhere on the body. They may appear on the eyebrows, eyelids, ears and skin creases near the mouth and nose.
Scalp lesions in infants (cradle cap) can appear yellowish and greasy. They usually cause no discomfort.
Depending on your pattern of skin symptoms, your doctor will ask about your:
Personal and family allergy history
History of exposure to irritating chemicals
Contact with potential allergy triggers, such as poison ivy
In many cases, your doctor can diagnose eczema by examining the skin.
If your doctor suspects that allergies are involved, patch testing with various allergy-causing chemicals may be necessary.
Duration depends on the type of eczema. Symptoms may go away after a week or two. Or they may persist for years.
There are many things you can do to prevent or reduce eczema flare-ups.
Avoid exposure to:
Extreme temperatures
Dry air
Harsh soaps
Perfumed products
Bubble baths
Use blankets and clothing made of cotton. Avoid more irritating fabrics, such as wool. Avoid stiff synthetics, such as polyester.
After showering or bathing, pat dry (rather than rub). That way, you leave a little moisture on your skin. Then apply a moisturizing cream or lotion to trap moisture in the skin.
Use a humidifier to add moisture to indoor air during the winter heating season.
To help to prevent contact dermatitis, avoid skin contact with:
Dish detergent, cleaning solutions, and other irritating chemicals
Plants
Jewelry
Substances that trigger skin allergies
If you have leg swelling, you can help prevent stasis dermatitis by:
Your doctor should review your skin care routine. Your doctor can ensure you are doing everything possible to prevent symptoms.
But sometimes eczema remains bothersome despite these measures.
Your doctor may prescribe a corticosteroid ointment or cream. In atopic dermatitis, mild or medium strength topical steroids generally are used. These are applied to the affected areas of the skin.
Strong steroids and oral antihistamines may be needed to treat allergic contact dermatitis.
If there are signs of bacterial skin infection, oral antibiotics usually are needed.
Sometimes, in very severe cases of eczema, your doctor will prescribe a short course of oral steroids or stronger immunosuppressants. However, these medications can have serious side effects. They must be used cautiously.
In some people, treatment with ultraviolet (UV) light is another option.
Seborrhea in adults is best treated with dandruff shampoo. Occasionally prescription antifungal facial creams or rinses may be needed.
Cradle cap in infants eventually clears up without treatment. However, it can last several months. The crust usually can be loosened. To do so, apply baby oil to the scalp 30 to 60 minutes before brushing with a soft brush. Then wash with baby shampoo.
When treating a contact allergy in a child, avoid topical treatments containing antihistamines. Skin reactions can occur.
Call your doctor if you have an area of skin that is red and very itchy. Also call if your skin is cracked, blistered or painfully dry.
Ask your doctor for an urgent evaluation if you have signs of infection. These include an area of skin that:
The prognosis varies from person to person. It depends on the type of eczema and its response to treatment.
Most contact dermatitis heals within two to three weeks. Most stasis dermatitis lasts for years.
About half of children with atopic eczema still have the problem as adults.
Drugs associated with:
Micromedex Care Notes:
National Eczema Foundation4460 Redwood Highway, Suite 16D San Rafael, CA 94903-1953 Phone: (415) 499.3474 Toll-Free:(800) 818-7546 Fax: (415) 472-5345 http://www.nationaleczema.org
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Eczema Guide: Causes, Symptoms and Treatment Options
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Seven foods to eat if you have eczema – Chatelaine
Posted: July 14, 2016 at 4:19 pm
Quatre Saisons/ Getty Images
Now is typically the time when eczema sufferers start complaining about their painful, dry, cracked skin. Its when no amount of moisturizer alleviates the insatiable itch or the embarrassment of having less-than-perfect skin.
If youre an eczema sufferer, I can sympathize. Mine is a severe condition that Ive battled into adulthood. Interestingly, winter is my favourite time of the year sweaters, scarves, socks and pants help me cover up my cracked scaly skin, scabby blisters and blotchy hyper-pigmentation.
To say the least Im something of an expert when it comes to eczema you name it, Ive tried it. Topical steroids that thinned out my skin? Check. Tar soaps, oatmeal baths and natural detergents? Check, check and check. Nothings worked long-term. That is until one day a friend suggested I avoid foods high in histamine. It seemed obvious why hadnt I thought of that before? Foods high in histamine would naturally cause an allergic response and inflammation. So thus began the journey that eventually led me to The Eczema Diet. In the book, by nutritionist Karen Fischer, I discovered seven foods that help decrease inflammation, promote skin repair and are considered eczema-safe.
The top seven eczema-healthy foods are:
1. Banana: High in potassium, contains histamine-lowering nutrients, magnesium and vitamin C.
2. Beef or chicken broth: Provides skin-repairing amino acid glycine.
3. Potato: Rich in fibre, potassium, vitamin C and is alkalizing.
4. Green onions: Contain histamine-lowering, anti-inflammatory quercetin and rich source of vitamin K, important for healthy skin.
5. Buckwheat: Gluten-free and contains quercetin to lower histamine and has strong anti-inflammatory effect
6. Rice milk: Low allergy and low in chemicals and considered eczema safe
7. Mung bean sprouts:Strong alkalizing food
There are many more eczema-healthy foods (like fish, beans and loads of vegetables), but the only foolproof way to check if specific foods are causing your breakouts is by cutting out common culpritsfor 14 days then reintroducing them back into your diet one-by-one to see if they cause a reaction. Remember: sometimes it can take a few days for symptoms to appear. You can follow this guide by Dr. Natasha Turner, or get more info from The Eczema Diet.
I also found that taking an igG test proved very helpful. It helped steer me in the right direction so that I knew for sure which foods were causing me grievance. Turns out egg, milk, soy and yeast were among the list and having that kind of clarity was life-changing, not only for my physical well-being, but my emotional well-being as well.
To read more about preventing and treating eczema click here.
Do you suffer from eczema? Have diet and nutrition helped alleviate your symptoms? Share in the comments below.
Try these no-cook banana snack ideas
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Seven foods to eat if you have eczema - Chatelaine
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Chamomile: A herbal medicine of the past with bright future
Posted: June 25, 2016 at 10:52 am
Abstract
Chamomile is one of the most ancient medicinal herbs known to mankind. It is a member of Asteraceae/Compositae family and represented by two common varieties viz. German Chamomile (Chamomilla recutita) and Roman Chamomile (Chamaemelum nobile). The dried flowers of chamomile contain many terpenoids and flavonoids contributing to its medicinal properties. Chamomile preparations are commonly used for many human ailments such as hay fever, inflammation, muscle spasms, menstrual disorders, insomnia, ulcers, wounds, gastrointestinal disorders, rheumatic pain, and hemorrhoids. Essential oils of chamomile are used extensively in cosmetics and aromatherapy. Many different preparations of chamomile have been developed, the most popular of which is in the form of herbal tea consumed more than one million cups per day. In this review we describe the use of chamomile in traditional medicine with regard to evaluating its curative and preventive properties, highlight recent findings for its development as a therapeutic agent promoting human health.
Keywords: chamomile, dietary agents, flavonoids, polyphenols, human health
The interplay of plants and human health has been documented for thousands of years (13). Herbs have been integral to both traditional and non-traditional forms of medicine dating back at least 5000 years (2, 46). The enduring popularity of herbal medicines may be explained by the tendency of herbs to work slowly, usually with minimal toxic side effects. One of the most common herbs used for medicinal purposes is chamomile whose standardized tea and herbal extracts are prepared from dried flowers of Matricaria species. Chamomile is one of the oldest, most widely used and well documented medicinal plants in the world and has been recommended for a variety of healing applications (7). Chamomile is a native of the old World and is a member of the daisy family (Asteraceae or Compositae). The hollow, bright gold cones of the flowers are packed with disc or tubular florets and are ringed with about fifteen white ray or ligulate florets, widely represented by two known varieties viz. German chamomile (Matricaria chamomilla) and Roman chamomile (Chamaemelum nobile) (8) . In this review we will discuss the use and possible merits of chamomile, examining its historical use and recent scientific and clinical evaluations of its potential use in the management of various human ailments.
Different classes of bioactive constituents are present in chamomile, which have been isolated and used as medicinal preparations and cosmetics (9). The plant contains 0.24%1.9% volatile oil, composed of a variety of separate oils. When exposed to steam distillation, the oil ranges in color from brilliant blue to deep green when fresh but turns to dark yellow after storage. Despite fading, the oil does not lose its potency. Approximately 120 secondary metabolites have been identified in chamomile, including 28 terpenoids and 36 flavonoids (10, 11). The principal components of the essential oil extracted from the German chamomile flowers are the terpenoids -bisabolol and its oxide azulenes including chamazulene and acetylene derivatives. Chamazulene and bisabolol are very unstable and are best preserved in an alcoholic tincture. The essential oil of Roman chamomile contains less chamazulene and is mainly constituted from esters of angelic acid and tiglic acid. It also contains farnesene and -pinene. Roman chamomile contains up to 0.6% of sesquiterpene lactones of the germacranolide type, mainly nobilin and 3-epinobilin. Both -bisabolol, bisabolol oxides A and B and chamazulene or azulenesse, farnesene and spiro-ether quiterpene lactones, glycosides, hydroxycoumarins, flavanoids (apigenin, luteolin, patuletin, and quercetin), coumarins (herniarin and umbelliferone), terpenoids, and mucilage are considered to be the major bio-active ingredients (12, 13). Other major constituents of the flowers include several phenolic compounds, primarily the flavonoids apigenin, quercetin, patuletin as glucosides and various acetylated derivatives. Among flavonoids, apigenin is the most promising compound. It is present in very small quantities as free apigenin, but predominantly exists in the form of various glycosides (1418).
Chamomile is known to be used in various forms of its preparations. Dry powder of chamomile flower is recommended and used by many people for traditionally established health problems. Medicinal ingredients are normally extracted from the dry flowers of chamomile by using water, ethanol or methanol as solvents and corresponding extracts are known as aqueous, ethanolic (alcoholic) and/or methanolic extracts. Optimum chamomile extracts contain about 50 percent alcohol. Normally standardized extracts contain 1.2% of apigenin which is one of the most effective bioactive agents. Aqueous extracts, such as in the form of tea, contain quite low concentrations of free apigenin but include high levels of apigenin-7-O-glucoside. Oral infusion of chamomile is recommended by the German Commission E (19, 20).Chamomile tea is one of the worlds most popular herbal teas and about a million cups are consumed every day. Tea bags of chamomile are also available in the market, containing chamomile flower powder, either pure or blended with other popular medicinal herbs. Chamomile tincture may also be prepared as one part chamomile flower in four parts of water having 12% grain alcohol, which is used to correct summer diarrhea in children and also used with purgatives to prevent cramping. Chamomile flowers are extensively used alone, or combined with crushed poppy-heads, as a poultice or hot foment for inflammatory pain or congestive neuralgia, and in cases of external swelling, such as facial swelling associated with underlying infection or abscess. Chamomile whole plant is used for making herb beers, and also for a lotion, for external application in toothache, earache, neuralgia and in cases of external swelling (20). It is also known to be used as bath additive, recommended for soothing ano-genital inflammation (21). The tea infusion is used as a wash or gargle for inflammation of the mucous membranes of the mouth and throat (22, 23). Inhalation of the vaporized essential oils derived from chamomile flowers is recommended to relieve anxiety, general depression. Chamomile oil is a popular ingredient of aromatherapy and hair care (24, 25). Roman chamomile is widely used in cosmetic preparations and in soothing and softening effect on the skin (26, 27).
Traditionally, chamomile has been used for centuries as an anti-inflammatory, antioxidant, mild astringent and healing medicine (28). As a traditional medicine, it is used to treat wounds, ulcers, eczema, gout, skin irritations, bruises, burns, canker sores, neuralgia, sciatica, rheumatic pain, hemorrhoids, mastitis and other ailments (29, 30). Externally, chamomile has been used to treat diaper rash, cracked nipples, chicken pox, ear and eye infections, disorders of the eyes including blocked tear ducts, conjunctivitis, nasal inflammation and poison ivy (31, 32). Chamomile is widely used to treat inflammations of the skin and mucous membranes, and for various bacterial infections of the skin, oral cavity and gums, and respiratory tract. Chamomile in the form of an aqueous extract has been frequently used as a mild sedative to calm nerves and reduce anxiety, to treat hysteria, nightmares, insomnia and other sleep problems (33). Chamomile has been valued as a digestive relaxant and has been used to treat various gastrointestinal disturbances including flatulence, indigestion, diarrhea, anorexia, motion sickness, nausea, and vomiting (34, 35). Chamomile has also been used to treat colic, croup, and fevers in children (36). It has been used as an emmenagogue and a uterine tonic in women. It is also effective in arthritis, back pain, bedsores and stomach cramps.
The flowers of chamomile contain 12% volatile oils including alpha-bisabolol, alpha-bisabolol oxides A & B, and matricin (usually converted to chamazulene and other flavonoids which possess anti-inflammatory and antiphlogistic properties (12, 19, 35, 36). A study in human volunteers demonstrated that chamomile flavonoids and essential oils penetrate below the skin surface into the deeper skin layers (37). This is important for their use as topical antiphlogistic (anti-inflammatory) agents. One of chamomiles anti-inflammatory activities involve the inhibition of LPS-induced prostaglandin E(2) release and attenuation of cyclooxygenase (COX-2) enzyme activity without affecting the constitutive form, COX-1 (38).
Most evaluations of tumor growth inhibition by chamomile involve studies with apigenin which is one of the bioactive constituents of chamomile. Studies on preclinical models of skin, prostate, breast and ovarian cancer have shown promising growth inhibitory effects (3943). In a recently conducted study, chamomile extracts were shown to cause minimal growth inhibitory effects on normal cells, but showed significant reductions in cell viability in various human cancer cell lines. Chamomile exposure induced apoptosis in cancer cells but not in normal cells at similar doses (18). The efficacy of the novel agent TBS-101, a mixture of seven standardized botanical extracts including chamomile has been recently tested. The results confirm it to have a good safety profile with significant anticancer activities against androgen-refractory human prostrate cancer PC-3 cells, both in vitro and in vivo situation (44).
Common cold (acute viral nasopharyngitis) is the most common human disease. It is a mild viral infectious disease of the upper respiratory system. Typically common cold is not life-threatening, although its complications (such as pneumonia) can lead to death, if not properly treated. Studies indicate that inhaling steam with chamomile extract has been helpful in common cold symptoms (45); however, further research is needed to confirm these findings.
It has been suggested that regular use of flavonoids consumed in food may reduce the risk of death from coronary heart disease in elderly men (46). A study assessed the flavonoid intake of 805 men aged 6584 years who were followed up for 5 years. Flavonoid intake (analyzed in tertiles) was significantly inversely associated with mortality from coronary heart disease and showed an inverse relation with incidence of myocardial infarction. In another study (47), on twelve patients with cardiac disease who underwent cardiac catheterization, hemodynamic measurements obtained prior to and 30 minutes after the oral ingestion of chamomile tea exhibited a small but significant increase in the mean brachial artery pressure. No other significant hemodynamic changes were observed after chamomile consumption. Ten of the twelve patients fell into a deep sleep shortly after drinking the beverage. A large, well-designed randomized controlled trial is needed to assess the potential value of chamomile in improving cardiac health.
An apple pectin-chamomile extract may help shorten the course of diarrhea in children as well as relieve symptoms associated with the condition (47). Two clinical trials have evaluated the efficacy of chamomile for the treatment of colic in children. Chamomile tea was combined with other herbs (German chamomile, vervain, licorice, fennel, balm mint) for administration. In a prospective, randomized, double-blind, placebo-controlled study, 68 healthy term infants who had colic (2 to 8 weeks old) received either herbal tea or placebo (glucose, flavoring). Each infant was offered treatment with every bout of colic, up to 150 mL/dose, no more than three times a day. After 7 days of treatment, parents reported that the tea eliminated the colic in 57% of the infants, whereas placebo was helpful in only 26% (P<0.01). No adverse effects with regard to the number of nighttime awakenings were noted in either group (48). Another study examined the effects of a chamomile extract and apple pectin preparation in 79 children (age 0.55.5 y) with acute, non-complicated diarrhea who received either the chamomile/pectin preparation (n = 39) or a placebo (n = 40) for 3 days. Diarrhea ended sooner in children treated with chamomile and pectin (85%), than in the placebo group (58%) (49). These results provide evidence that chamomile can be used safely to treat infant colic disorders.
Topical applications of chamomile have been shown to be moderately effective in the treatment of atopic eczema (50). It was found to be about 60% as effective as 0.25% hydrocortisone cream (51). Roman chamomile of the Manzana type (Kamillosan (R)) may ease discomfort associated with eczema when applied as a cream containing chamomile extract. The Manzana type of chamomile is rich in active ingredients and does not exhibit chamomile-related allergenic potential. In a partially double-blind, randomized study carried out as a half-side comparison, Kamillosan(R) cream was compared with 0.5% hydrocortisone cream and a placebo consisting only of vehicle cream in patients suffering from medium-degree atopic eczema (52). After 2 weeks of treatment, Kamillosan(R) cream showed a slight superiority over 0.5% hydrocortisone and a marginal difference as compared to placebo. Further research is needed to evaluate the usefulness of topical chamomile in managing eczema.
Chamomile is used traditionally for numerous gastrointestinal conditions, including digestive disorders, "spasm" or colic, upset stomach, flatulence (gas), ulcers, and gastrointestinal irritation (53). Chamomile is especially helpful in dispelling gas, soothing the stomach, and relaxing the muscles that move food through the intestines. The protective effect of a commercial preparation (STW5, Iberogast), containing the extracts of bitter candy tuft, lemon balm leaf, chamomile flower, caraway fruit, peppermint leaf, liquorice root, Angelica root, milk thistle fruit and greater celandine herb, against the development of gastric ulcers has been previously reported (54). STW5 extracts produced a dose dependent anti-ulcerogenic effect associated with a reduced acid output, an increased mucin secretion, an increase in prostaglandin E (2) release and a decrease in leukotrienes. The results obtained demonstrated that STW5 not only lowered gastric acidity as effectively as a commercial antacid, but was more effective in inhibiting secondary hyperacidity (54).
Studies suggest that chamomile ointment may improve hemorrhoids. Tinctures of chamomile can also be used in a sitz bath format. Tincture of Roman chamomile may reduce inflammation associated with hemorrhoids (55, 56).
It has been claimed that consumption of chamomile tea boosts the immune system and helps fight infections associated with colds. The health promoting benefits of chamomile was assessed in a study which involved fourteen volunteers who each drank five cups of the herbal tea daily for two consecutive weeks. Daily urine samples were taken and tested throughout the study, both before and after drinking chamomile tea. Drinking chamomile was associated with a significant increase in urinary levels of hippurate and glycine, which have been associated with increased antibacterial activity (57). In another study, chamomile relieved hypertensive symptoms and decreased the systolic blood pressure significantly, increasing urinary output (58). Additional studies are needed before a more definitive link between chamomile and its alleged health benefits can be established.
Inflammation is associated with many gastrointestinal disorders complaints, such as esophageal reflux, diverticular disease, and inflammatory disease (5961). Studies in preclinical models suggest that chamomile inhibits Helicobacter pylori, the bacteria that can contribute to stomach ulcers (60). Chamomile is believed to be helpful in reducing smooth muscle spasms associated with various gastrointestinal inflammatory disorders. Chamomile is often used to treat mild skin irritations, including sunburn, rashes, sores and even eye inflammations (6265) but its value in treating these conditions has not been shown with evidence-based research.
Mouth ulcers are a common condition with a variety of etiologies (66). Stomatitis is a major dose-limiting toxicity from bolus 5-fluorouracil-based (5-FU) chemotherapy regimens. A double-blind, placebo-controlled clinical trial including 164 patients was conducted (22). Patients were entered into the study at the time of their first cycle of 5-FU-based chemotherapy and were randomized to receive a chamomile or placebo mouthwash thrice daily for 14 days. There was no suggestion of any stomatitis difference between patients randomized to either protocol arm. There was also no suggestion of toxicity. Similar results were obtained with another prospective trial on chamomile in this situation. Data obtained from these clinical trials did not support the pre study hypothesis that chamomile could decrease 5-FU-induced stomatitis. The results remain unclear if chamomile is helpful in this situation.
Osteoporosis is a metabolic bone disease resulting from low bone mass (osteopenia) due to excessive bone resorption. Sufferers are prone to bone fractures from relatively minor trauma. Agents which include selective estrogen receptor modulators or SERMs, biphosphonates, calcitonin are frequently used to prevent bone loss. To prevent bone loss that occurs with increasing age, chamomile extract was evaluated for its ability to stimulate the differentiation and mineralization of osteoblastic cells. Chamomile extract was shown to stimulate osteoblastic cell differentiation and to exhibit an anti-estrogenic effect, suggesting an estrogen receptor-related mechanism (67). However, further studies are needed before it can be considered for clinical use.
Traditionally, chamomile preparations such as tea and essential oil aromatherapy have been used to treat insomnia and to induce sedation (calming effects). Chamomile is widely regarded as a mild tranquillizer and sleep-inducer. Sedative effects may be due to the flavonoid, apigenin that binds to benzodiazepine receptors in the brain (68). Studies in preclinical models have shown anticonvulsant and CNS depressant effects respectively. Clinical trials are notable for their absence, although ten cardiac patients are reported to have immediately fallen into a deep sleep lasting for 90 minutes after drinking chamomile tea (47). Chamomile extracts exhibit benzodiazepine-like hypnotic activity (69). In another study, inhalation of the vapor of chamomile oil reduced a stress-induced increase in plasma adrenocorticotropic hormone (ACTH) levels. Diazepam, co-administered with the chamomile oil vapor, further reduced ACTH levels, while flumazenile, a BDZ antagonist blocked the effect of chamomile oil vapor on ACTH. According to Paladini et al. (70), the separation index (ratio between the maximal anxiolytic dose and the minimal sedative dose) for diazepam is 3 while for apigenin it is 10. Compounds, other than apigenin, present in extracts of chamomile can also bind BDZ and GABA receptors in the brain and might be responsible for some sedative effect; however, many of these compounds are as yet unidentified.
Chamomile has been reported in the treatment of generalized anxiety disorder (GAD). But the reports seem contradictory as an earlier report suggests that German chamomile showed significant inhibition of GAD activity (71). The recent results from the controlled clinical trial on chamomile extract for GAD suggests that it may have modest anxiolytic activity in patients with mild to moderate GAD (72). Extracts of chamomile (M. recutita) possess suitable effects on seizure induced by picrotoxin (73). Furthermore, apigenin has been shown to reduce the latency in the onset of picrotoxin-induced convulsions and reduction in locomotor activity but did not demonstrate any anxiolytic, myorelaxant, or anticonvulsant activities (16).
Studies suggest that chamomile ameliorates hyperglycemia and diabetic complications by suppressing blood sugar levels, increasing liver glycogen storage and inhibition of sorbitol in the human erythrocytes (74). The pharmacological activity of chamomile extract has shown to be independent of insulin secretion (75), and studies further reveal its protective effect on pancreatic beta cells in diminishing hyperglycemia-related oxidative stress (76). Additional studies are required to evaluate the usefulness of chamomile in managing diabetes.
The efficacy of lubrication of the endo-tracheal tube cuff with chamomile before intubation on postoperative sore throat and hoarseness was determined in a randomized double-blind study. 161 patients whose American Society of Anesthesiologists (ASA) physical status was I or II, and undergoing elective surgical, orthopedic, gynecological or urological surgeries were divided in two groups. The study group received 10 puffs of chamomile extract (Kamillosan M spray, total 370 mg of Chamomile extract) at the site of the cuff of the endotracheal tube for lubrication, while the control group did not receive any lubrication before intubations. Standard general anesthesia with tracheal intubations was given in both groups. 41 out of 81 patients (50.6%) in the chamomile group reported no postoperative sore throat in the post-anesthesia care unit compared with 45 out of 80 patients (56.3%) in the control group. Postoperative sore throat and hoarseness both in the post-anesthesia care unit and at 24 h post-operation were not statistically different. Lubrication of endo-tracheal tube cuff with chamomile extract spray before intubations can not prevent post operative sore throat and hoarseness (77). Similar results were obtained in another double blind study (78).
Vaginal inflammation is common in women of all ages. Vaginitis is associated with itching, vaginal discharge, or pain with urination. Atrophic vaginitis most commonly occurs in menopausal and postmenopausal women, and its occurrence is often associated with reduced levels of estrogen. Chamomile douche may improve symptoms of vaginitis with few side effects (79). There is insufficient research data to allow conclusions concerning possible potential benefits of chamomile for this condition.
The efficacy of topical use of chamomile to enhance wound healing was evaluated in a double-blind trial on 14 patients who underwent dermabrasion of tattoos. The effects on drying and epithelialization were observed, and chamomile was judged to be statistically efficacious in producing wound drying and in speeding epithelialization (80). Antimicrobial activity of the extract against various microorganisms was also assessed. The test group, on day 15, exhibited a greater reduction in the wound area when compared with the controls (61 % versus 48%), faster epithelialization and a significantly higher wound-breaking strength. In addition, wet and dry granulation tissue weight and hydroxyproline content were significantly higher. The increased rate of wound contraction, together with the increased wound-breaking strength, hydroxyproline content and histological observations, support the use of M. recutita in wound management (81). Recent studies suggest that chamomile caused complete wound healing faster than corticosteroids (82). However, further studies are needed before it can be considered for clinical use.
Essential oils obtained from Roman chamomile are the basic ingredients of aromatherapy. Clinical trials of aromatherapy in cancer patients have shown no statistically significant differences between treated and untreated patients (83). Another pilot study investigated the effects of aromatherapy massage on the anxiety and self-esteem experience in Korean elderly women. A quasi-experimental, control group, pretest-posttest design used 36 elderly females: 16 in the experimental group and 20 in the control group. Aromatherapy massage using lavender, chamomile, rosemary, and lemon was given to the experimental group only. Each massage session lasted 20 min, and was performed 3 times per week for two 3-week periods with an intervening 1-week break. The intervention produced significant differences in the anxiety and self-esteem. These results suggest that aromatherapy massage exerts positive effects on anxiety and self-esteem (8486). However, more objective, clinical measures should be applied in a future study with a randomized placebo-controlled design.
A relatively low percentage of people are sensitive to chamomile and develop allergic reactions (87). People sensitive to ragweed and chrysanthemums or other members of the Compositae family are more prone to develop contact allergies to chamomile, especially if they take other drugs that help to trigger the sensitization. A large-scale clinical trial was conducted in Hamburg, Germany, between 1985 and 1991 to study the development of contact dermatitis secondary to exposure to a mixture of components derived from the Compositae family. Twelve species of the Compositae family, including German chamomile, were selected and tested individually when the mixture induced allergic reactions. During the study, 3,851 individuals were tested using a patch with the plant extract (88). Of these patients, 118 (3.1%) experienced an allergic reaction. Further tests revealed that feverfew elicited the most allergic reactions (70.1% of patients) followed by chrysanthemums (63.6%) and tansy (60.8%). Chamomile fell in the middle range (56.5%). A study involving 686 subjects exposed either to a sesquiterpene lactone mixture or a mixture of Compositae extracts led to allergic reactions in 4.5% of subjects (89). In another study it was shown that eye washing with chamomile tea in hay fever patients who have conjunctivitis exacerbates the eye inflammation, whereas no worsening of eye inflammation was noted when chamomile tea was ingested orally (90). Chamomile is listed on the FDA's GRAS (generally recognized as safe) list. It is possible that some reports of allergic reactions to chamomile may be due to contamination of chamomile by "dog chamomile," a highly allergenic and bad-tasting plant of similar appearance. Evidence of cross-reactivity of chamomile with other drugs is not well documented, and further study of this issue is needed prior to reaching conclusions. Safety in young children, pregnant or nursing women, or those with liver or kidney disease has not been established, although there have not been any credible reports of toxicity caused by this common beverage tea.
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8. Hansen HV, Christensen KIb. The common chamomile and the scentless may weed revisited. Taxon. International Association for Plant Taxonomy. 2009;Vol. 58:261264.
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10. Mann C, Staba EJ. In herbs, spices and medicinal plants: recent advances in botany. In: Craker LE, Simon JE, editors. Horticulture and Pharmacology. Phoenix, Arizona: Oryx Press; 1986. pp. 235280.
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45. Saller R, Beschomer M, Hellenbrecht D. Dose dependency of symptomatic relief of complaints by chamomile steam inhalation in patients with common cold. Eur J Pharmacol. 1990;183:728729.
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Chamomile: A herbal medicine of the past with bright future
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Eczema (atopic dermatitis) – Better Health Channel
Posted: May 28, 2016 at 2:42 pm
Atopic dermatitis (commonly known as eczema) is an inherited, chronic inflammatory skin condition that usually appears in early childhood. Patches of skin become red, scaly and itchy. Sometimes, tiny blisters containing clear fluid can form and the affected areas of skin can weep. Weeping is a sign that the dermatitis has become infected, usually with the bacterium Staphylococcus aureus (golden staph). Eczema is not contagious.
Eczema can vary in severity and symptoms may flare up or subside from day to day. If your eczema becomes worse, disrupts sleep or becomes infected, see your doctor.
Using moisturisers and cortisone-based ointments can help ease the symptoms. It is also important to avoid skin irritants, such as soap, hot water and synthetic fabrics.
Children with eczema have a higher risk of developing food allergies, asthma and hay fever later in childhood.
Although you only need only one copy of the gene to form a normal skin barrier, two copies are important for skin barrier repair. If a persons skin is exposed to irritants and their skin barrier is affected, a person with only one copy of the gene may find that their ability to repair the skin barrier is limited.
Once the skin barrier is disrupted, moisture leaves the skin and the skin will become dry and scaly. Environmental allergens (irritants from the persons surrounds) can also enter the skin and activate the immune system, producing inflammation that makes the skin red and itchy.
You are more likely to get eczema if your family has a history of eczema or allergic conditions, including hay fever and asthma.
In most cases, eczema is not caused or aggravated by diet. If you feel a food is to blame, see your doctor or a dietitian for proper allergy testing and dietary advice.
While eczema causes stress, and stress may increase the energy with which you scratch, stress does not in itself cause eczema.
Suggestions for washing include:
Suggestions for reducing skin irritation include:
Hard physical activity or exercise that makes you sweat heavily can also trigger the itch of eczema.
Suggestions include:
Never self-diagnose or you risk depriving yourself of enjoyable and nutritious foods for no good reason. Unnecessarily avoiding certain foods (such as dairy products) can lead to nutritional deficiencies.
Using high-strength topical steroids for extended periods, especially on delicate areas like the face, can cause side effects, including thinning of the skin. It is best to apply the cream to reddened areas after bathing, but make sure the skin is thoroughly dry.
In severe cases of eczema, a short course of oral corticosteroids may be necessary. This must be done under careful medical supervision because symptoms may become worse once you have finished taking the tablets.
Pimecrolimus cream is a non-steroid anti-inflammatory cream that can help reduce flare-ups of eczema if applied at the first signs of eczema.
A person with stubborn eczema may need up to 30 sessions. The risks of unsupervised ultraviolet radiation therapy can be the same as for sunbathing faster ageing of the skin and greater risk of skin cancer.
Because of these risks, and the need for close and regular monitoring, oral anti-inflammatory treatment is only considered in severe cases of eczema that are difficult to control with other therapies.
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Eczema and Food Allergies: Is Food to Blame for a Rash?
Posted: May 8, 2016 at 3:41 am
Eczema (also known as atopic dermatitis) is a type of skin rash that's characterized by itchiness, redness, and scaliness. Although there are several possible causes, some common foods -- including eggs, milk, wheat, peanuts and soy -- can trigger eczema or make it worse in people who are prone to it.
The rash most commonly appears on the knees, elbows, cheeks, arms and legs, although it can be seen on other parts of the body, as well.
Eczema occurs most commonly in children. Worldwide, some 10% to 20% of children develop eczema, with about half of those being diagnosed before they're one year old.
Fortunately, most children with eczema will either completely outgrow their symptoms or find that their symptoms improve significantly by the time they reach adulthood. About 10% of eczema cases occur for the first time in adolescents or adults.
Eczema is associated with a variety of so-called allergic conditions, including asthma, respiratory allergies, and allergic rhinitis. Eczema has a genetic component; children born into families with a history of asthma, hay fever, eczema, or other allergic disorders are more likely to develop eczema.
About one-third of eczema patients develop the rash in response to food triggers. In fact, eczema can make allergy testing difficult -- it can make skin testing almost impossible.
(In these cases, blood tests for allergies may be helpful.)
In addition, food allergens can sometimes cause eczema to worsen or "flare up." In people with eczema and food allergies, strictly avoiding food allergens may help reduce or, occasionally, eliminate symptoms.
The most common food triggers for eczema are eggs, milk, peanuts, soy, and wheat.
Among these, eggs are probably associated the most strongly with eczema. Because of the high number of eczema patients who have food allergies, studies recommend that food allergy screening be a part of testing anyone newly diagnosed with eczema, especially children who are newly diagnosed.
There are a variety of possible non-food triggers for eczema, as well. In addition to food allergens, eczema can be exacerbated by stress, physical irritants (like excess dryness in the air or itchy clothing), airborne allergens like dust and pollen, and some infections.
Eczema treatment consists of avoiding any known triggers or skin irritants (whether they're allergenic, emotional, or physical), treating skin dryness, and reducing inflammation.
Your doctor may treat skin dryness with special lotions or with wet dressings. Drugs that are used to control inflammation include topical corticosteroids like Cultivate (fluticasone) and Dermatop (prednicarbate). Occasionally, doctors prescribe shorter courses of oral steroids like prednisone to treat severe eczema, but these drugs are generally not used for long periods of time.
Studies have examined whether late introduction of solid foods, breastfeeding, or supplements of probiotics (helpful bacteria that live in the small intestines) can help prevent eczema in high-risk children.
While studies have not found a compelling reason for parents to delay introducing solid foods beyond the current AAP recommendation of four months, exclusive breastfeeding for four to six months does seem to help. Several studies have shown that probiotic supplements in infants might help prevent eczema or reduce its effects, but this research is not considered conclusive. Talk to your doctor before giving your infant probiotics.
Eczema is a major "quality-of-life" disorder for families dealing with it the skin condition can be quite painful and can be distressing for both children and parents.
Allergy testing to determine whether food allergies are a trigger for eczema can be useful in helping ease symptoms of eczema. If you or your child have eczema and are found through testing to be allergic to a food, strictly avoiding that food may help you reduce eczema symptoms.
Families may be disappointed, though, to find that a food allergen-free diet isn't a "magic bullet." Not everyone with food allergies and eczema finds that abstaining from food triggers eliminates or even substantially reduces their eczema (although many see some success with this strategy).
Your allergist can give you guidance about what to expect after your allergy testing and can help you relieve symptoms of eczema through medication and home treatment.
In addition, your doctor needs to know if an eczema rash becomes painful, unusually swollen, or accompanied by a fever, since these are all signs of bacterial infection. Keep in mind that eczema tends to be most severe in children under the age of five, and that many families will find that children's symptoms are, if not completely outgrown, far less severe as they grow older.
Sources:
Adkinson, N. Franklin, et al. "Chapter 86: Atopic Dermatitis." Middleton's Allergy: Principles and Practice. 6th Ed. Philadelphia: Mosby, Inc., 2003.
Allen SJ et al. Probiotics in the prevention of eczema: a randomised controlled trial. Archives of Disease in Childhood. 2014 Nov;99(11):1014-9.
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Eczema and Food Allergies: Is Food to Blame for a Rash?
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