Category Archives: Eczema

The latest report pertaining to Atopic Eczema Treatment Market now available with Market Study Report, LLC, provides a detailed analysis regarding market size, revenue estimations and growth rate of the industry. In addition, the report illustrates the major obstacles and newest growth strategies adopted by leading manufacturers who are a part of the competitive landscape of this market.

The latest report on the Atopic Eczema Treatment market entails latest industry data and projections backed by historical statistics and growth opportunities over the study period. In addition, the report comments on the impact of COVID-19 pandemic on this business sphere.

Request a sample Report of Atopic Eczema Treatment Market at:https://www.marketstudyreport.com/request-a-sample/3035313?utm_source=algosonline.com&utm_medium=SK

The report studies in complete details the multiple segmentations, inclusive of the product terrain, application spectrum, and regional territories. Key trends that will influence growth of each segment in the forthcoming years are factored in the report to impart a deeper understanding. Apart from this, a pool of leading players is assessed in the study to decipher the competitive dynamics of this industry vertical.

Main highlights from the Atopic Eczema Treatment market report:

Geographical landscape of the Atopic Eczema Treatment market:

Atopic Eczema Treatment market segmentation: Americas, APAC, Europe, Middle East & Africa

A gist of the regional analysis:

Product types and application spectrum of the Atopic Eczema Treatment market:

Product landscape:

Types: Oral, Topical and Parenteral

Main highlights listed in the report:

Application spectrum:

Application scope: Hospital Pharmacies, Retail Pharmacies and Online Pharmacies

Specifics mentioned in the document:

Ask for Discount on Atopic Eczema Treatment Market Report at:https://www.marketstudyreport.com/check-for-discount/3035313?utm_source=algosonline.com&utm_medium=SK

Competitive outlook of the Atopic Eczema Treatment market:

Companies profiled in the study: Leo Pharma, Velite Pharmaceutical, Anacor Pharmaceutical, Regeneron Pharmaceuticals, Pfizer and Sanofi

Key pointers from the report:

Important Questions answered in this report are:

For More Details On this Report: https://www.marketstudyreport.com/reports/global-atopic-eczema-treatment-market-growth-status-and-outlook-2020-2025

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Global Atopic Eczema Treatment Market is anticipated to grow at a strong CAGR by 2025 - AlgosOnline

While the wait and see approach may work for some aspects of kids health, research is showing that it is not helpful for pediatric allergies, which can progress from eczema to other complications like asthma without early intervention. AllergyEasy is helping to stop this progression with a child-friendly alternative to allergy shots.

AllergyEasy provides family doctors and pediatricians with a turnkey allergy treatment program. This allows the doctors to prescribe sublingual immunotherapy (SLIT), which is a needle-free, hassle-free alternative to allergy shots. Like allergy shots, SLIT desensitizes the body to allergens in the environment so that it can tolerate them without overreacting. But instead of antigen being injected into the skin, it is dispensed as under-the-tongue drops. And because it is safer than shots, it can be taken at home rather than at the doctors office.

SLIT is particularly important for young children, who may not be eligible for allergy shots because of safety concerns. However, research on a phenomenon known as the allergic march shows that if kids allergies continue untreated, they could face worsening allergic rhinitis and asthma as they grow.

Studies on the allergic march are making clear that its not just nice to intervene early but that its essential in preventing allergy-related surgeries and illnesses and chronic allergic diseases later in life, said Stuart Agren, M.D., Founder and President of AllergyEasy.

The term allergic march or atopic march is used to describe the progression of atopic disorders, such as eczema in babies to allergic rhinitis and asthma in children, teens and adults.

Agren cited early studies on this topic, including the PAT Study, which was published in the Journal of Allergy and Clinical Immunology in 2002. It showed that pollen immunotherapy reduces the development of asthma in children with seasonal allergies. A 10-year follow-up showed long-term clinical effects with significant improvement persisting seven years after children stopped their immunotherapy treatment.

Another study published in the World Allergy Organization Journal in 2008 centered specifically on sublingual immunotherapy, predicting that this new promising treatment will modify the severity of atopic eczema in infants and young children and will decrease the risk for the eventual development of asthma and thus prevent the consequences of the allergic march.

Allergy drops have been shown to be safe for children under age 5, allowing doctors to intervene early for children who suffer from allergies from young ages. Shots, on the other hand, arent usually prescribed until children are at least 7 years old due to safety concerns.

Doctors in 32 states prescribe AllergyEasys sublingual immunotherapy allergy drops. Unlike many allergy shot programs, the drops contain a comprehensive mix of allergens, including dust, mold, pet dander and the countrys most prevalent pollens. This ensures thorough coverage against the full range of allergy triggers, not just a few local pollens.

AllergyEasy drops are available to patients of all ages with a prescription from a physician. To learn more about AllergyEasy and how the pediatricians who prescribe it are helping to halt the allergic march, visit http://www.AllergyEasy.com or call (877) 276-3393.

About AllergyEasy

AllergyEasy helps allergy doctors around the country provide sublingual immunotherapy (allergy drops) to their patients who suffer with allergies to pollen and food allergies (including dairy allergy, wheat allergy, nut allergy, fruit allergy and more.) AllergyEasy can connect patients to a doctor in their area who offers sublingual allergy treatment.

Disclaimer: The statements made regarding these products have not been evaluated by the Food and Drug Administration. The information on this website or in emails is designed for educational purposes only. It is not intended to be a substitute for informed medical advice or care. You should not use this information to diagnose or treat any health problems or illnesses without consulting your physician. The news site hosting this press release is not associated with AllergyEasy or Dr. Stuart Agren. It is merely re-publishing a press release announcement submitted by a company, without any stated or implied endorsement of the product or service.

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AllergyEasy Urges Early Intervention Through Kid-safe Allergy Drops to Limit Asthma - PRUnderground

8-Mar-2021

Ingredients

Omegablue is part of the Givaudan Active Beautys upcycling collection launched in October 2020

Givaudan Active Beauty launches Omegablue, a cosmetic ingredient created from upcycled wild bilberries used for advanced skin repair.

A plant that grows in Central and Northern Europe, weve upcycled the seeds to craft a natural ingredient to revert skin dryness, irritation, and desquamation caused by lipid barrier damage.

As waste reduction is a new sustainable standard today, consumers are re-evaluating their daily routines, including their beauty regimes, to contribute to minimising waste overall.

Actually, beauty consumers are already acting in that direction as cosmetic products containing recycled or upcycled ingredients are appealing to 69% of them, mostly in Brazil (80%) and China (74%).

Consumers are ready to go forward, pushing upcycling beauty products as a top trend for the years to come, without compromising the main needs of their skin protection.

Traditionally used by the food industry for their juice and sugar, bilberries are also an amazing source of anthocyanidins extracted from the pulp and fruit skin for the supplement and pharma industries.

Furthermore, the tiny seeds of the berries contain up to 20% of linoleic acid (omega-6) and -linolenic acid (omega-3) in an optimal ratio; these compounds being both known for their capabilities to improve hydration and skin barrier functionality.

Giada Maramaldi, Personal Care Category Manager says: "Crafted by a supercritical CO2 procedure in an upcycled process from the seeds of this unique Vaccinum myrtillus berry, Omegablue was developed as a topical soothing agent for sensitive and damaged skin. It effectively calms skin discomfort in a transient or curative way and contains sebum-like essential fatty acids forming a protective barrier from external agents."

The efficacy of Omegablue has been shown in surfactant-induced depletion during clinical tests. After 3 days from the damage, the treated area has completely restored the skin barrier function.

Omegablue is also significantly performant on chronic inflammation challenged skin (psoriasis) as it significantly decreases erythema severity, down to 27% and scales formation by 28% in four weeks.

Even better results are shown on eczema challenged skin condition as erythema severity decreased by 37.5% and itch rating by 42.8%.

Additionally, the PASI (Psoriasis Area Severity Score) and EASI (Eczema Area Severity Score) are markedly ameliorated by 27% and 35% respectively.

The extremely light and silky touch of Omegablue has been formulated in S.O. Smooth, our shower oil crafted to highlight the power of our upcycled ingredient in a body care application.

The formula will clean and protect the skin from external aggressions. Enriched with chia oil, a natural ingredient that gently nourishes, it will restore and maintain the skin barrier (Omegablue) to bring the skin back to its comfort zone.

Omegablue is part of the Givaudan Active Beautys upcycling collection launched in October 2020. This collection includes 8 other functional ingredients in various categories.

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Givaudan Active Beauty presents Omegablue, an upcycled ingredient dedicated to skin repair - Cosmetics Business

If you're constantly scratching dry, red patches of skin, you may be wondering if you have eczema. Depending on where that angry itch is, however, psoriasis could be your first guess. The two chronic skin conditions are distinctly different to doctors and experts who treat them, but can be very difficult to distinguish for people who are experiencing it firsthand.

They are often confused, Frank Wang, M.D., a dermatologist at Michigan Medicine at the University of Michigan, tells Good Housekeeping. They can look very similar. They both present with red patches and plaques that are scaly and can be itchy, and they can affect similar areas of the body.

With input from skin care professionals, we're helping you determine whether your skin ailment is eczema or psoriasis and tips for getting started on treatment.

Eczema isn't actually one condition all its own; the diagnosis refers to a group of skin conditions that cause itchiness, inflammation and rashes, according to the National Eczema Association (NEA). Your bout of eczema may include one of seven common conditions that affect more than 30 million Americans, including atopic dermatitis, contact dermatitis and others.

Atopic dermatitis is the most common form of eczema, Dr. Wang says. It usually starts in early childhood and features itchy rashes, most routinely on the face and in the soft spot behind the knees, that come and go.

Itchiness is the most common symptom of all types of eczema. Though, it affects people in different ways. Some only have mild itchiness, while others are so itchy that they scratch until their skin bleeds.

Other symptoms, according to the NEA, include:

Psoriasis affects about 8 million Americans, and like eczema, there are several types. The most common is called plaque psoriasis, according to the American Academy of Dermatology Association (AAD), and symptoms include:

The plaques, which can be large or small, may appear anywhere on the body but are typically on the scalp, knees, elbows and lower back.

Psoriasis can affect other parts of the body, too, including the joints, causing the condition known as psoriatic arthritis. About 30% of people with psoriasis develop psoriatic arthritis, Dr. Wang says. According to AAD, symptoms include:

Eczema and psoriasis are different chronic conditions, though they both cause red, itchy skin rashes. But for doctors, these rashes have slight differences that the trained eye can usually detect.

Atopic dermatitis tends to have less well-defined borders, doesn't have as much thick scale as psoriasis and tends to be just a little bit more crusty, Dr. Wang explains. Overall, atopic dermatitis tends to be itchier. Both are itchy conditions, but atopic dermatitis is probably more itchy.

Neither condition is contagious, and eczema and psoriasis cant be prevented.

Scientists arent sure exactly what causes eczema, but its likely genetic and triggered by allergic reactions to items like soap or fragrance, or could be onset by dry skin, Dr. Wang says. Environmental factors, like cigarette smoke, pollution and stress, could also trigger eczema, per AAD experts.

Research suggests that the immune systems in people with eczema likely overreact, causing inflammation when they come in contact with certain triggers, which makes the skin red and itchy.

Like eczema, theres no exact known cause for psoriasis, but it too has an immune system link. Psoriasis is caused by an overactive immune system that revs up the production of new skin cells. According to the National Psoriasis Foundation, skin cells typically grow and fall off within a month, but in people with psoriasis, skin cells go through this process in just a few days. Instead of falling off, the cells pile up on the skin, creating thick, scaly patches, which experts call plaques.

Eczema and psoriasis are completely different conditions. So, eczema cant turn into psoriasis, and vice versa. But, since the conditions can look so similar, it can be tough to tell the difference even in a clinical setting, especially in children. According to AAD, in these instances, a dermatologist may diagnose the skin condition as psoriasiform dermatitis.

Theres some overlap, too. Its not common, but you can technically get both psoriasis and eczema at the same time, which can be extra confusing. Your dermatologist will usually be able to distinguish between the two.

Eczema and psoriasis arent entirely curable. But, Dr. Wang says they can be treated and managed to reduce pain, control itching and minimize flare-ups of patches and plaques. Whether you're dealing with one condition or the other (or, both!), managing eczema and psoriasis starts with a skincare specialist best identifying your triggers. You'll work to avoid these irritating events, and you'll also treat any sustained skin injuries that may add to pain or irritation. Mostly, you'll work to stay out of the sun and use solutions to help avoid scratching your skin.

Mild cases of both conditions can be treated at home. Dr. Wang suggests using a mild soap, over-the-counter hydrocortisone and emollients, which are therapeutic moisturizers. There are also lotions and creams for both eczema and psoriasis available to consumers.

If your skin doesnt respond to at-home treatments, or the eczema or psoriasis exhibit more aggressive symptoms than ever before, its time to visit the dermatologist. Always discuss long-term treatment with your care provider when resorting to over-the-counter products.

Treatments will vary based on how severe the condition is and patient preference, Dr. Wang explains, but usually include topical steroids, light therapy and prescription drugs for the inflammation. For severe psoriasis, when patients have 10% to 30% of their body covered in plaques, injectable medications, called biologics, are used.

Since theres no cure, treatment and management of eczema and psoriasis will often be lifelong, Dr. Wang says. This can impact quality of life, interfere with sleep and even cause anxiety and depression; all issues that you should discuss with your primary care provider, who may refer you to additional specialists for those issues. Having a skin disorder such as eczema and psoriasis can be very emotionally and physically disabling, he says. People can feel extremely self-conscious. It can really hinder their self-confidence, and it can be very stigmatizing.

But know you're not alone, and that there are treatments that can help you.

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Psoriasis Vs. Eczema: What's the Difference in Symptoms and Treatments? - GoodHousekeeping.com

Skin discoloration can happen on any type of skin. However, it may be more apparent when it occurs on darker skin. Skin conditions, such as acne or eczema, could discolor black skin.

Many treatments can reduce skin discoloration, including laser therapy and chemical peels. Home remedies may include creams that contain vitamin C or retinol.

A person should speak with a dermatologist before trying any sort of treatment. A dermatologist specializes in treating skin conditions and can suggest a product or treatment that is a good match for an individuals skin type. A person may find a dermatologist directly, or they may receive a referral from their doctor.

Below, we look at the different causes of discoloration on black skin and how to treat it.

Discoloration on dark skin can happen for a variety of reasons, including:

Skin discoloration causes skin to look lighter (hypopigmented) or darker (hyperpigmented).

Hyperpigmentation is when the skin becomes highly pigmented and appears darker than usual. This results in dark spots.

Acne, eczema, wound healing, and sun exposure can all cause hyperpigmentation.

A form of hyperpigmentation called melasma typically occurs with hormonal changes. Pregnancy or some types of hormonal birth control could cause melasma.

Postinflammatory hyperpigmentation is common in dark skin and may develop after an injury or inflammatory response. The resulting dark spots and discoloration sometimes last for years.

With hypopigmentation, the skin loses its pigment and becomes lighter than usual. A person can be born with hypopigmentation or they can acquire it.

Like hyperpigmentation, hypopigmentation may occur once a wound heals. It is also much more noticeable on black skin.

Vitiligo is a condition that causes melanin-producing cells to malfunction, leaving some patches of skin lighter than others.

Hypopigmentation from inflammation or infection usually resolves on its own. However, hypopigmentation from scarring is more difficult to alleviate and people respond differently to vitiligo treatment.

Learn more about vitiligo here.

Causes of discoloration on the face include:

Discoloration of the hands can happen because of:

Potential reasons for discoloration on the legs include:

The American Academy of Dermatology (AAD) say that skin-lightening creams can help reduce hyperpigmentation.

However, it is advisable to buy these from a reputable retailer. Some creams may contain toxic ingredients, including mercury. Creams that do not meet stringent manufacturing safety standards may cause rashes, make discoloration worse, and exert other harmful effects on the body.

Before trying any treatment or cream, a person should either contact a dermatologist directly or speak with their doctor. A doctor may treat the condition on their own, or they may refer an individual to a dermatology department.

A person should notice their skin getting better when they stop using products that cause skin irritation and discoloration. However, it can take up to a year for some dark spots to fade.

To alleviate skin discoloration and scarring people may want to use products that contain:

Therapies that help alleviate skin discoloration include laser therapy and chemical peels.

However, a person may experience some side effects from these treatments. For example, laser therapy can help reduce dark spots but may produce hypopigmentation around the affected area. It can also worsen hyperpigmentation in some cases.

Learn more about laser therapy for scars here.

If a person notices a sudden patch of discoloration that does not go away, or gets worse, they should speak with a doctor. It is important to talk with a doctor about sudden skin discoloration as it could be a sign of skin cancer.

Similarly, if a person feels self-conscious about skin discoloration, they should talk with a dermatologist. They can suggest treatment options to reduce hypopigmentation or hyperpigmentation. A person can find a dermatologist directly or seek a referral from their doctor.

In some cases, discoloration is unavoidable.

With acne, wounds, and sunburn, some strategies can help prevent discoloration. These include:

When a person has eczema, emollients and lotions may help provide relief from itching.

While most skin discoloration is nothing to worry about, in some cases it could be a symptom of skin cancer.

According to the AAD, people of color often receive skin cancer diagnoses when their cancer is at a later stage. Because of this, it is crucial that people of color do regular skin checks.

Addressing the underlying cause of the discoloration may help reduce any future instances of hypopigmentation or hyperpigmentation. However, in some cases, hypopigmentation or hyperpigmentation can be permanent, especially if it is present at birth.

If a person has concerns about discoloration on their skin, they should speak with a dermatologist. In many cases, medical treatments may produce better results than at-home remedies. A person can contact a dermatologist directly or receive a referral from their doctor.

Skin discoloration is often harmless and not usually cause for concern. However, a person should speak with their doctor if they notice sudden changes in skin color, or the discoloration is spreading or getting worse.

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What causes black skin discoloration? Is it treatable? - Medical News Today

We recently spoke to Alex to get a first hand account of living with psoriasis here in the UK

My psoriasis flares up about once a month, which leaves me looking like I have third-degree burns on my face, legs, and stomach. Most of my friends dont understand it, and Im not really sure my doctor does either. Through research, and trial and error, I have learned how to manage my psoriasis, sort of. I just wish there were a magic cream out there that would make it go away for good.

We recently spoke with Alex to get a first-hand account of what its like for someone living with psoriasis in the UK, and to understand how we, as healthcare communicators, can potentially help.

Psoriasis has a profound impact on someones physical and psychological wellbeing. Flare-ups can damage confidence, limit social activity, and reduce intimacy. However, these impacts are often downplayed by those living with it.

When my psoriasis flares up I feel very self-conscious. Ive got more confident with age, but a few years ago I wouldnt wear shorts if I was having a flare-up because of how bad it looks. I would rather have an eczema flare-up than a psoriasis one. Whilst eczema hurts a lot more, it doesnt look nearly as bad, and more often than not, I can fix it.

Topical treatments are the first-line option for people living with psoriasis in the UK. The volume of available options makes it easy for people to be prescribed cream after cream, despite the fact they are having little effect on their psoriasis. Topical treatments are also expensive.

Psoriasis is a chronic condition, with little awareness amongst HCPs and the public. This can make it difficult, and often frustrating, for people living with psoriasis to continually explain their condition to others.

When I call my GP to discuss a flare up, I can hear them scrolling through all of the creams Ive had in the past. Yet they just give me another one. Ive got a drawer full of lotions and potions that do very little to make my skin better.

Alexs lotions and potions

Alexs experience is not uncommon, the majority of people find themselves being cycled through topical treatments by their GP, with little to no effect on their condition. Despite the fact that there are a number of systemic treatments now available, one studied showed that fewer than 7,000 people living with psoriasis (out of a possible 1.8 million[i]) received a biologic therapy in the UK in 2012.[ii]

Systemic treatments are typically reserved for the most severe cases. However, people with moderate/severe psoriasis can gain access to more effective treatments, if the doctor determines the impact on their life to be significant enough.

This is commonly determined by two indices, developed by theBritish Association of Dermatologists:

These indices have been around for a while, yet Alex (and many others), have little to no knowledge of their existence, or how they are used. In fact, a study revealed that only 32% of people living with psoriasis reported having their disease severity measured.[i]

Helping people understand how these tools are used by doctors, and giving them the skills to gather evidence about their condition between appointments, is an important step towards improving long-term outcomes.

There is a clear gap in understanding on both sides of the psoriasis care pathway. GPs receive little dermatology training, making it difficult for them to truly understand the impact that the condition is having on a patients life.

For those living with it, navigating a complex treatment pathway, with limited access to specialist dermatologists[ii] and whilst managing flare-ups, are significant challenges to achieving long-term goals.

Clear skin is somewhat of a perceived fantasy for most people living with psoriasis. They may have seen one or two people achieve it, but not fully understand the route taken to get there. The lack of information about how treatment decisions are made and the journey to clear skin makes it difficult for people to forge their own path there.

Having clear skin would make me confident, content, and comfortable. However, without some sort of magic cream, I dont see that it is possible. There isnt enough evidence out there.

As healthcare communicators, we have a role to play in working with the patient community to inspire the belief that achieving clear skin is possible and co-creating tools and resources to help them achieve it.

By sharing best practices, success stories, and real-life examples of others achieving clear skin, we can support the belief that clear skin is possible. We can also help to activate people living with psoriasis by focusing on three core pillars:

Activating people living with psoriasis to play a role in their treatment decisions involves three key steps:

Activating patients to take control of their health is something we at Aurora have done for our clients many times over the years. Get in touch with one of the team to find out more: piteam@auroracomms.com

[i] Psoraisis Patients Association about psoriasis. Psoriasis Patients Association 2017. Available at:https://www.psoriasis-association.org.uk/about-psoriasis Last accessed: February 2021. Last reviewed: March 2019

[ii] NICE Psoriasis Quality Standards Indicator. National Institute of Health and Care Excellence 2012. Available at:https://www.nice.org.uk/guidance/qs40/documents/psoriasis-briefing-paper2

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Living with psoriasis: a patient perspective - PMLiVE

NEW YORK, March 1, 2021 /PRNewswire/ -- Hoth Therapeutics, Inc. (NASDAQ: HOTH), abiopharmaceutical company, is pleased to announceit has completed recruitment of Cohort 1 for its upcoming first in human clinical trial of the proprietary BioLexa platform to treat atopic dermatitis, also known as eczema.

"We believe there continues to be an unmet need for improved topical therapy for those patients suffering from mild to moderate eczema," stated Robb Knie, CEO of Hoth Therapeutics, "We are pleased with how quickly Cohort 1 of Part A of our clinical trial has reached full recruitment and we are hopeful to announce preliminary results from this trial later in the year. We are continuing our mission to bring patient focused therapies to the clinic and improve quality of life across multiple indications."

About Hoth Therapeutics, Inc.

Hoth Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing new generation therapies for unmet medical needs. Hoth's pipeline development is focused to improve the quality of life for patients suffering from indications including atopic dermatitis, skin toxicities associated with cancer therapy, chronic wounds, psoriasis, asthma, acne, and pneumonia. Hoth has also entered into two different agreements to further the development of two therapeutic prospects to prevent or treat COVID-19. To learn more, please visitwww.hoththerapeutics.com.

Forward-Looking Statement

This press release includes forward-looking statements based upon Hoth's current expectations which may constitute forward-looking statements for the purposes of the safe harbor provisions under the Private Securities Litigation Reform Act of 1995 and other federal securities laws, and are subject to substantial risks, uncertainties and assumptions. These statements concern Hoth's business strategies; the timing of regulatory submissions; the ability to obtain and maintain regulatory approval of existing product candidates and any other product candidates we may develop, and the labeling under any approval we may obtain; the timing and costs of clinical trials, the timing and costs of other expenses; market acceptance of our products; the ultimate impact of the current Coronavirus pandemic, or any other health epidemic, on our business, our clinical trials, our research programs, healthcare systems or the global economy as a whole; our intellectual property; our reliance on third party organizations; our competitive position; our industry environment; our anticipated financial and operating results, including anticipated sources of revenues; our assumptions regarding the size of the available market, benefits of our products, product pricing, timing of product launches; management's expectation with respect to future acquisitions; statements regarding our goals, intentions, plans and expectations, including the introduction of new products and markets; and our cash needs and financing plans. There are a number of factors that could cause actual events to differ materially from those indicated by such forward-looking statements. You should not place reliance on these forward-looking statements, which include words such as "could," "believe," "anticipate," "intend," "estimate," "expect," "may," "continue," "predict," "potential," "project" or similar terms, variations of such terms or the negative of those terms. Although the Company believes that the expectations reflected in the forward-looking statements are reasonable, the Company cannot guarantee such outcomes. Hoth may not realize its expectations, and its beliefs may not prove correct. Actual results may differ materially from those indicated by these forward-looking statements as a result of various important factors, including, without limitation, market conditions and the factors described in the section entitled "Risk Factors" in Hoth's most recent Annual Report on Form 10-K and Hoth's other filings made with the U. S. Securities and Exchange Commission. All such statements speak only as of the date made. Consequently, forward-looking statements should be regarded solely as Hoth's current plans, estimates, and beliefs. Investors should not place undue reliance on forward-looking statements. Hoth cannot guarantee future results, events, levels of activity, performance or achievements. Hoth does not undertake and specifically declines any obligation to update, republish, or revise any forward-looking statements to reflect new information, future events or circumstances or to reflect the occurrences of unanticipated events, except as may be required by applicable law.

Investor Contact:LR Advisors LLCEmail:investorrelations@hoththerapeutics.comwww.hoththerapeutics.comPhone: (678) 570-6791

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SOURCE Hoth Therapeutics, Inc.

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Hoth Therapeutics Completes Site Recruitment for Cohort 1 of First in Human Clinical Trial of BioLexa for the Treatment of Atopic Dermatitis -...

Cold, dry weather can present many problems to people. It can lead to garden struggles, pipe malfunctions, and all-around general discomfort.

Colder, dryer weather can also result in skin and lips becoming very dry and irritated.

The cause of this is not directly from the cold weather, but from the adverse effects cold weather brings.

Heather Winn, OSU Extension family and consumer science educator, said heating up the home is one of the causes of dry skin.

"It's not that our skin behaves differently when it is cold; it's the added lower humidity and-or the effects of heating our homes that causes our skin to be dryer in the wintertime," said Winn. "Those things, in addition to the regular conditions like bathing, soap, etc., cause the water content of our skin to be lower, with the result being dry, itchy skin."

This can also worsen the effects of already existing skin conditions, such as atopic dermatitis, better known as eczema. One of Winn's children has this condition, so she is well-versed on methods to care for dry skin.

"My youngest son has eczema, which is exacerbated during the winter months," said Winn. "We have had a lot of experience in dealing with these issues since he was a baby. If someone has super-dry skin or eczema, a wet wrap is a great way to relieve itchy dry skin."

Along with this, there are several other efficient ways to combat the itchiness and discomfort of dry skin.

"Staying hydrated is very important during cold or dry weather," said Winn.

"Take showers or baths lukewarm instead of hot. When you get out of the shower or bath, immediately put on lotion to seal in moisture from bathing."

Other ways to help dry skin include adding humidifiers to the home, continuing to wear sunscreen throughout the day, and wearing gloves when outside or in a closed area.

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5Ws+1H: How It's Done: Best way to combat dry skin in the cold - Tahlequah Daily Press

MedicalResearch.com Interview with:

Dr. Richard Gallo, MD, PhDIma Gigli Distinguished Professor of DermatologyChair of the Department of DermatologyUC San Diego School of Medicine

MedicalResearch.com: What is the background for this study? Would you briefly explain what is meant by atopic dermatitis/eczema? How common is it and what are the symptoms.

Response: Atopic Dermatitis is a common inflammatory disease of the skin that appears in up to 20% of children and 3% of the adult population. People suffering from atopic dermatitis have red, itchy skin. In many cases this rash will disrupt sleeping and severely impact quality of life. Also, people with atopic dermatitis are more susceptible to infections of the skin and are more likely to have other allergies and asthma.

MedicalResearch.com: What are the main findings?

Response: This paper shows how a bacteria that is found on healthy human skin can be used safely to treat people with atopic dermatitis. A total of 54 adults were treated in a double-blind, placebo controlled human trial. The technique used is a transformational approach to treating disease since we specifically chose the bacteria for use based on specific bacterial genes that were missing from the microbiome of atopic patients. The exciting part of the work is that this is the first time the approach of targeted bacteriotherapy has been used for a skin disease, and the trial shows it is safe and helped most of the patients who received it.

MedicalResearch.com: What should readers take away from your report?

Response: The paper adds to the growing body of evidence that shows how dependent we are on some bacteria for our health. Discovering beneficial bacteria has taken many years since most bacteria are not helpful or even dangerous. This is a breakthrough study since it confirms which bacterial genes are needed to benefit patients with atopic dermatitis.

MedicalResearch.com: What recommendations do you have for future research as a result of this work?

Response: With this as a proof of principle we can now expand the size of the study to include more patients and to apply this approach to more diseases.We have also expanded our screening platform to look at other skin diseases and are excited to advance these programs into the clinic.

Any disclosures?

The technology described in the study has been licenced by MatriSys Bioscience, a San Diego based biotechnology company. Dr. Gallo is cofounder and a member of the MatriSys scientific advisory board.

Citation:

Teruaki Nakatsuji, Tissa R. Hata, Yun Tong, Joyce Y. Cheng, Faiza Shafiq, Anna M. Butcher, Secilia S. Salem, Samantha L. Brinton, Amanda K. Rudman Spergel, Keli Johnson, Brett Jepson, Agustin Calatroni, Gloria David, Marco Ramirez-Gama, Patricia Taylor, Donald Y. M. Leung, Richard L. Gallo.Development of a human skin commensal microbe for bacteriotherapy of atopic dermatitis and use in a phase 1 randomized clinical trial.Nature Medicine, 2021; DOI:10.1038/s41591-021-01256-2

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Last Modified: Feb 24, 2021 @ 11:46 pm

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Bacteria From Healthy Human Skin Can Be Used to Treat Atopic Dermatitis - Eczema - MedicalResearch.com

If youve been to a spa, beauty counter, or scrolled through Instagram lately, youve probably seen the unsettling and Michael Myers la Halloween-esque LED face masks. The devices are kinda creepy, definitely futuristic, and promise all sorts of skin miracles like the reversal of everything from wrinkles, redness, and signs of aging to acne, scarring, and dark spots, according to Harvard Womens Health Watch. That all sounds great, but the how and why behind all these benefits is far from obvious when looking at the colorful face mask in action. Good thing L'OFFICIEL is here to demystify the process and give so you you all the facts beforeyou consider getting robo-masked up.

LED light therapy, otherwise known as Dermalux LED Phototherapy, is a non-invasive skin rejuvenation treatment. Using a narrow band ofnon-thermal LED light energy, the procedure stimulates your bodys natural cell production for an accelerated repair of the skins surface.By speeding up skins regenerative process, evidence of sun damage, acne, inflammation, or even more serious conditions like eczema, psoriasis, dermatitis, and rosacea is reduced. For people with wounds or other kinds of scarring, the regrowth of skin cells as promoted by LED Phototherapy can also be curative.

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Everything You Need to Know About LED Light Therapy - LED Light Face Mask Skin Care Phototherapy - L'Officiel