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Category Archives: Eczema

Atopic Dermatitis Day: Everything You Need To Know About This Skin Condition – Doctor NDTV

Posted: September 14, 2021 at 4:21 pm

Atopic dermatitis (eczema) is a skin condition that leads to redness and itchiness. It's common in children but can occur at any age.

Atopic dermatitis usually develops in early childhood

Atopic Dermatitis (AD) is the most common form of eczema. It is an inflammatory skin condition, a chronic long-lasting disease characterized by dry, itchy skin that oozes or can weep clear fluid when scratched and flares up periodically. The exact cause is unknown but personal history of allergies, allergies, family history of eczema, asthma, or hay fever, are major risk factors for atopic dermatitis.

Common symptoms on the basis which AD is diagnosed, especially who are suffering from moderate to severe AD are rashes that can potentially cover much of the body and can include rough, leathery, or scaly patches, intense persistent itching, skin wounds and dryness, pain, cracking, redness, or darkness, crusting and oozing.

Burden around Atopic Dermatitis

AD affects at least 2 % to 3% of adults and 25% of children. It is also stated that about 10% -15 % of Indian population, has some form of atopy and manifestation of AD since the 1st year of their life. The burden of atopic dermatitis (AD) is high. Moderate to severe childhood AD shows greater family impact than type-1 diabetes.

This chronic condition has significant disease burden and higher prevalence of atopic and psychological comorbidities, impaired health - related quality of life, anxiety, and depression. The burden is even higher among patients with inadequately controlled AD. About 90% of AD patients experience daily itch and two- thirds have sleep disturbance. Comorbidities included other atopic disorders, infections, obesity, growth disturbance, deficit hyperactivity disorder and mental health disease, speech disorder, headaches, organ specific autoimmunity, and anemia. Persistent disease is particularly costly and appears to correlate with later onset, preexisting duration, and severity. However, persistent, early onset particularly herald possible future food and respiratory allergy, with their attendant burdens (and more severe) disease appears to.

Need for awareness and better treatment

Experts have observed that patients suffering from AD have a 44% more likelihood of mental health issuesas compared to those without atopic dermatitis. Patients often suffer from disturbed sleep, low work productivity, increased activity impairment and susceptibility to suicidal behavior. Which emphasizes the fact that atopic dermatitis aggravates and impacts not just physical and mental health, but it also leads to development of other disorders.

People living with AD are also predisposed to bacterial, viral, and fungal skin infections. Majority of the adults try treating AD with OTC products, until it reaches a severe level, which cannot be ignored. This is due to lack of awareness on the disease. However, this can be changed by acting when you notice early signs and common symptoms of atopic dermatitis and visit the dermatologist on priority.

Early diagnosis and providing access to optimal care and timely treatment for patients living with AD can help them live a better quality of life. By and large 80-85% AD hits children between 2-15 years of age when, physical and mental development, studies, career development are the priority. Hence AD has a far-reaching consequence on the future psycho-social growth of a child suffering from AD.

(Dr. Sandipan Dhar is aProfessor & Head of Paediatric Dermatology atInstitute of Child Health, Kolkata)

Disclaimer: The opinions expressed within this article are the personal opinions of the author. NDTV is not responsible for the accuracy, completeness, suitability, or validity of any information on this article. All information is provided on an as-is basis. The information, facts or opinions appearing in the article do not reflect the views of NDTV and NDTV does not assume any responsibility or liability for the same.

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Incyte Announces Ruxolitinib Cream Data Accepted for Presentation at the 2021 European Academy of Dermatology and Venereology (EADV) Virtual Congress…

Posted: at 4:21 pm

WILMINGTON, Del., September 13, 2021--(BUSINESS WIRE)--Incyte (Nasdaq:INCY) today announced that multiple abstracts highlighting data for ruxolitinib cream, an investigational topical JAK1/JAK2 inhibitor, in patients with vitiligo and atopic dermatitis (AD) will be presented at the upcoming European Academy of Dermatology and Venereology (EADV) 30th Anniversary Congress, held virtually from September 29-October 2, 2021.

The 24-week data from the Phase 3 TRuE-V program evaluating the safety and efficacy of ruxolitinib cream in adolescent and adult patients (age 12 years) with vitiligo will be presented as a late-breaking oral presentation. Incyte previously announced that both the TRuE-V1 and TRuE-V2 studies met the primary and key secondary endpoints.

"We look forward to sharing data demonstrating the potential of ruxolitinib cream as an effective treatment option for patients living with vitiligo with the dermatology community at this years EADV virtual congress," said Jim Lee, M.D., Ph.D., Group Vice President, Inflammation & Autoimmunity, Incyte. "These data from the Phase 3 TRuE-V program underscore our commitment to bringing new therapies to patients with challenging skin diseases."

Key abstracts include:

Late-Breaking Oral Presentation

Vitiligo

Efficacy and Safety of Ruxolitinib Cream for the Treatment of Vitiligo: 24-Week Results From 2 Randomized, Double-Blind Phase 3 Studies (Abstract #D3T01.2A. Session: Late Breaking News. Saturday, October 2, 5:15-6:15 a.m. ET)

Oral Presentation

Atopic Dermatitis

Efficacy and Safety of Ruxolitinib Cream among Patients Aged 65 Years with Atopic Dermatitis: Pooled Results from Two Phase 3 Studies (Abstract #FC01.01. Session: Atopic dermatitis/Eczema. Thursday, September 30, 4:00-4:10 a.m. ET)

Poster Presentations

Atopic Dermatitis

Story continues

Efficacy of Ruxolitinib Cream for the Treatment of Atopic Dermatitis by Baseline Clinical Characteristics (encore) (Abstract #P0187. Session: Atopic dermatitis/Eczema)

Efficacy of Ruxolitinib Cream among Patients with Atopic Dermatitis Based on Previous Medication History (encore) (Abstract #P0192. Session: Atopic dermatitis/Eczema)

Effects of Ruxolitinib Cream in Patients with Atopic Dermatitis with Baseline Body Surface Area 10% and Eczema Area and Severity Index Score 16 (encore) (Abstract #P0190. Session: Atopic dermatitis/Eczema)

Patient-Reported Outcomes of Ruxolitinib Cream for the Treatment of Atopic Dermatitis (encore) (Abstract #P0188. Session: Atopic dermatitis/Eczema)

More information regarding the virtual conference is available on the EADV website: https://www.eadvcongress2021.org/. Following the conference, all e-Posters will be made available online on http://www.eadv.org for EADV members.

About Ruxolitinib Cream

Ruxolitinib cream is a proprietary formulation of Incytes selective JAK1/JAK2 inhibitor ruxolitinib that has been designed for topical application. Ruxolitinib cream is currently in Phase 3 development for the treatment of adolescents and adults with atopic dermatitis (TRuE-AD) and vitiligo (TRuE-V). Incyte has worldwide rights for the development and commercialization of ruxolitinib cream.

About Incyte Dermatology

Incytes science-first approach and expertise in immunology has formed the foundation of the company. In Dermatology, the Companys research and development efforts are focused on leveraging our knowledge of the JAK-STAT pathway to identify and develop topical and oral therapies with the potential to modulate immune pathways driving uncontrolled inflammation and help restore normal immune function.

Currently, Incyte is exploring the potential of JAK inhibition for a number of immune-mediated dermatologic conditions with a high unmet medical need, including atopic dermatitis, vitiligo and hidradenitis suppurativa. To learn more, visit the Dermatology section of Incyte.com.

About Incyte

Incyte is a Wilmington, Delaware-based, global biopharmaceutical company focused on finding solutions for serious unmet medical needs through the discovery, development and commercialization of proprietary therapeutics. For additional information on Incyte, please visit Incyte.com and follow @Incyte.

Forward-Looking Statements

Except for the historical information set forth herein, the matters set forth in this press release, including statements regarding Incytes TRuE-V clinical program, whether and when ruxolitinib cream might be approved to treat patients with vitiligo or atopic dermatitis (AD), the potential for success of such treatment, and Incytes Dermatology program generally, contain predictions, estimates and other forward-looking statements.

These forward-looking statements are based on the Companys current expectations and subject to risks and uncertainties that may cause actual results to differ materially, including unanticipated developments in and risks related to: unanticipated delays; further research and development and the results of clinical trials possibly being unsuccessful or insufficient to meet applicable regulatory standards or warrant continued development; the ability to enroll sufficient numbers of subjects in clinical trials; the effects of the COVID-19 pandemic and measures to address the pandemic on the Companys clinical trials, supply chain, other third-party providers and development and discovery operations; determinations made by the U.S. FDA and other regulatory authorities outside of the United States; the efficacy or safety of the Companys products; the acceptance of the Companys products in the marketplace; market competition; sales, marketing, manufacturing and distribution requirements; and other risks detailed from time to time in the Companys reports filed with the Securities and Exchange Commission, including its annual report and its quarterly report on Form 10-Q for the quarter ended June 30, 2021. The Company disclaims any intent or obligation to update these forward-looking statements.

View source version on businesswire.com: https://www.businesswire.com/news/home/20210913005816/en/

Contacts

Media Catalina Loveman+1 302 498 6171cloveman@incyte.com

Jenifer Antonacci+1 302 498 7036jantonacci@incyte.com

Investors Christine Chiou+1 302 274 4773cchiou@incyte.com

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Incyte Announces Ruxolitinib Cream Data Accepted for Presentation at the 2021 European Academy of Dermatology and Venereology (EADV) Virtual Congress...

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Eczema (Atopic Dermatitis): Causes, Treatment & Symptoms

Posted: September 10, 2021 at 5:24 am

OverviewWhat is eczema? What does it look and feel like?

Eczema (also called atopic dermatitis) is a condition that causes your skin to become dry, red, itchy and bumpy. Its one of many types of dermatitis. Eczema damages the skin barrier function (the "glue" of your skin). This loss of barrier function makes your skin more sensitive and more prone to infection and dryness.

Eczema doesnt harm your body. It doesnt mean that your skin is dirty or infected, and its not contagious. There are treatments that can help manage your symptoms.

In the word dermatitis, derm means skin and itis means inflammation. The word as a whole means inflammation of the skin. Eczema originates from the Greek word ekzein which means to boil over or break out.

Eczema affects up to 15 million Americans. Infants are prone to eczema and 10% to 20% will have it. However, nearly half outgrow the condition or have significant improvement as they get older.

Eczema affects males and females equally and is more common in people who have a personal or family history of asthma, environmental allergies and/or food allergies.

The first signs of eczema are itchiness and redness.

Eczema can show up anywhere on your skin. In teens and adults, its typically found on your hands, neck, inner elbows, ankles, knees, feet and around your eyes.

Eczema (atopic dermatitis) usually begins in childhood, but anyone at any age can get it. Youre high risk if you are:

No. No type of dermatitis is contagious. It cant be spread to anyone else.

Although some types of dermatitis are painful (contact dermatitis, for example) or cause a burning sensation, eczema is usually itchy.

Eczema and other types of dermatitis are not harmful to the rest of your body. The condition is not deadly.

Psoriasis and dermatitis can appear similar. Both cause patches of red skin. However, in psoriasis, the scales are thick and the edges of those scales are well-defined.

Discuss with your healthcare provider your questions about which type of skin condition you have. You can have more than one skin condition at a time. Treatments for one may not work for the other.

Eczema (atopic dermatitis) is caused by a combination of immune system activation, genetics, environmental triggers and stress.

Mental/emotional signs:

Physical signs:

Eczema (atopic dermatitis) symptoms include:

If you have eczema, you might also have another condition that doesnt cause it, but is often found alongside it:

Notice that diabetes is not included in this list.

Low humidity (dry air) can dry out your skin, and sweating caused by high heat can make the itchiness worse.

Eczema can be lifelong, but symptoms can be managed with at-home remedies, over-the-counter medications and prescribed medications.

Your healthcare provider will take a close look at your skin. They will look for classic signs of eczema such as a redness and dryness. They will ask about the symptoms youre experiencing.

Usually your healthcare provider will be able to diagnose eczema based on examining your skin. However, when there is doubt, they may perform the following tests:

The conversation with your healthcare provider will need to cover a lot of information. Be sure to be specific about your symptoms.

Treating eczema (atopic dermatitis) can be difficult if the cause is something you cant control, like genetics. Fortunately, you may have some influence over your environment and stress levels. Do your best to figure out what triggers or worsens your eczema, and then avoid it. The goal is to reduce itching and discomfort and prevent infection and additional flare-ups.

Consider these treatment tips:

If your child has skin problems, such as eczema, you can:

No. There are treatments, but no treatment can claim to eliminate the symptoms of dermatitis 100% of the time.

Yes, if your usual healthcare provider is unable to help with your eczema symptoms. Dermatologists specialize in skin conditions.

There are steps you can take that may prevent eczema outbreaks:

The connection between eczema and food allergies is unclear. If you have food allergies, then one of the reasons why you must avoid that food is that it may cause or worsen dermatitis. Examples of common allergies include peanuts, dairy, eggs, sugar, alcohol and gluten. Pay attention to what you eat. If your eczema flares up after you eat a certain food, then you might have an allergy to it.

If you dont have a food allergy then there are no foods, including chicken, that will cause or worsen your eczema.

Nearly half of children with eczema will outgrow the condition or experience great improvement by the time they reach puberty. Others will continue to have some form of the disease. For adults with eczema, the disease can be generally well-managed with good skin care and treatment, although flare-ups of symptoms can occur throughout life.

Eczema can be with you lifelong. It can start in infancy and continue through adulthood. It can start in the teenage years and disappear by young adulthood. Each possibility depends on the person.

Eczema is a chronic condition, which means that it cannot be cured. Treatments, however, are very effective in reducing the symptoms of itchy, dry skin.

Many people live with eczema (atopic dermatitis). As many as 15 million Americans may have this skin condition. Living with it can be challenging.

There may be times when your eczema disappears. This is known as a remission period. Other times you may have a flare-up, which is when it gets worse. The goal of treatment is to prevent such flare-ups, preventing your symptoms from getting worse. Be sure to avoid triggers, moisturize, take your medicine and do anything else your healthcare provider recommends.

Reducing your stress is very important. Try these tips:

See your dermatologist or other healthcare provider as soon as you notice symptoms. Get treatment right away.

A note from Cleveland Clinic

Eczema (atopic dermatitis) is very normal, very common, and very, very uncomfortable. It can affect your quality of life. At its worse it can keep you from sleeping, distract you and make you feel self-conscious in public. See your dermatologist or other healthcare provider as soon as you start to see signs of it. Explore at-home remedies and prescribed treatments.

Youre not alone! 15% to 20% of people experience eczema or another type of dermatitis at some point in their lives.

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7 Foods to Avoid in Babies and Toddlers with Eczema – Healthline

Posted: at 5:24 am

Also known as atopic dermatitis, eczema is a common condition characterized by red, itchy, and inflamed skin.

Although eczema can affect anyone, its especially common among children. In fact, about 60% of cases develop within the first year of life (1).

Many factors can worsen eczema flare-ups, including foods.

Research shows that certain foods may trigger eczema in 2030% of cases of moderate to severe eczema. Additionally, foods are more likely to worsen symptoms in children and infants under age 5 (2).

While foods do not directly cause eczema, making dietary changes could help reduce symptoms, especially for those who have a sensitivity or allergy to specific foods (3).

In children with a confirmed food allergy, eliminating trigger foods from the diet may significantly improve symptoms of eczema within just 12 months (4).

However, keep in mind that its not necessary to avoid all the foods listed below to help manage your childs eczema.

Certain foods may worsen symptoms of eczema, especially in children and infants. However, it depends on the childs particular allergies or sensitivities, so speak with a healthcare professional to determine which foods might be best to eliminate.

Research has shown that eliminating one or more of these foods from the diet may significantly improve symptoms of eczema in some children.

Not only is a cows-milk allergy the most common food allergy in young children, but dairy products like milk, yogurt, and cheese are also common triggers for eczema (6).

One study in 132 children with food-triggered eczema found that 39% of children developed an immediate reaction after consuming cows milk (2).

A 2019 review reported that infants with eczema were six times more likely to have an allergy to cows milk, eggs, or peanuts at 12 months of age compared with infants without eczema (7).

Fortunately, there are several simple plant-based milks available as an alternative to cows milk, including soy milk, almond milk, and cashew milk.

However, be sure to check the ingredients lists carefully, as some of these products are high in calories and added sugar.

The term shellfish refers to any aquatic animal that has a shell-like exterior, including crabs, lobsters, oysters, mussels, and shrimp. Meanwhile, most types of fish, including salmon, trout, tuna, and tilapia, have fins and scales.

Although both fish and shellfish are highly nutritious and can be great sources of protein and omega-3 fatty acids, they can also worsen symptoms of eczema for many children.

This is because fish and shellfish allergies are common and can cause a wide range of side effects, including hives, itching, and eczema (8, 9).

While some children may be sensitive to finned fish or shellfish, others may experience reactions only to certain types, such as crustaceans (like shrimp and crab) or mollusks (like oysters and clams) (8).

A pediatrician or registered dietitian can help determine which specific types of seafood may trigger symptoms for your baby or toddler.

For those with a soy allergy, consuming soy products like soy milk, tofu, or edamame can cause an immune response, which could trigger skin reactions such as eczema (10).

Compared with allergies to other major food allergens, soy allergies are not nearly as common (11, 12).

For example, one 2013 study in 175 people with eczema found that around 30% had an immune reaction to soy. However, only about 3% of people experienced symptoms, such as hives and itching, after consuming soy (13).

If your baby or toddler has a sensitivity to soy products, keep in mind that many processed foods contain soy-based ingredients, all of which could worsen symptoms of eczema. Examples include (14):

Some babies or toddlers may have an allergy to the proteins found in egg whites or yolks, which could trigger symptoms of eczema (15).

Egg allergy is one of the most common food allergies, affecting an estimated 1.3% of children under 5 in the United States (16).

Furthermore, one study reported that infants with eczema are nearly 6 times as likely to develop an egg allergy by 12 months of age compared with those without eczema (7).

However, most egg allergies in children resolve by around age 5 (17).

Additionally, some babies and toddlers who are sensitive to eggs may be able to tolerate them in some forms, such as baked eggs (16).

Tree nuts could worsen eczema for many young children with a tree nut allergy. Examples of tree nuts include:

Tree nut allergies are very common and may affect up to 4.9% of children and adults (18).

Unfortunately, tree nut allergies can be very serious, and some research suggests that more severe reactions to tree nuts are often associated with severe cases of eczema, asthma, and seasonal allergies (19).

In addition to avoiding tree nuts specifically, your child may need to avoid foods that contain tree nuts, including pesto, nut butters, coconut products, and certain types of cereals, cookies, crackers, or candies.

Wheat is a type of cereal grain and a staple ingredient in many foods, such as bread, pasta, and baked goods.

Gluten is a specific protein found in wheat, barley, and rye that gives dough its structure and elasticity.

For those with a wheat allergy, consuming products that contain wheat may worsen eczema and could also cause other symptoms, including hives, asthma, and digestive issues (20, 21).

Eczema and skin rashes can also be caused by a sensitivity to gluten, as well as by celiac disease, an autoimmune condition that triggers an immune reaction when gluten-containing foods are consumed (22, 23, 24).

While there is no test available to diagnose non-celiac gluten sensitivity, your childs pediatrician can use a skin or blood test to help determine if your child has celiac disease or an allergy to wheat.

Peanuts are a common allergen and are associated with several skin reactions, including rashes, hives, itching, and eczema (25).

Peanut allergies are especially common among babies and toddlers, as most peanut allergies appear within the first 2 years of life (25).

Additionally, some research shows that peanut allergies are more common among infants with moderate to severe eczema (26).

If peanuts cause flare-ups of eczema for your baby or toddler, try swapping other ingredients into your favorite recipes instead, such as seeds or seed butters.

Some of the most common foods that cause allergies in infants and toddlers are dairy, fish, shellfish, soy products, wheat, peanuts, tree nuts, and eggs.

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Teens eczema is so bad hes asked to be put in an ‘induced coma’ – Metro.co.uk

Posted: at 5:24 am

Barney is constantly bleeding from cuts (Picture: SWNS)

A desperate mum is trying to find a cure for her teenage sons crippling eczema.

Miranda Rae wants to help her 14-year-old son Barney who has the condition so bad that hes asked to be placed in an induced coma.

Barney says his skin constantly feels like its on fire and is so itchy that he often scratches himself until he is covered in blood.

The teen, who is due to start Year 10 this month, also finds it excruciating to wear school uniform.

Single mum Miranda has even tried to bandage Barneys body, but he rips these off as he sleeps.

The 50-year-old, from Bristol, says: One night he came into my room and was bleeding from head to toe.

He was shaking and said I cant believe Ive done this to myself.

Now hes terrified of sleeping because he ends up scratching when hes asleep.

Hes bleeding with cuts and puss all the time. Its constant, theres no second of relief.

Barney has suffered with eczema since he was four years old but last October his condition deteriorated.

Miranda adds: The worst thing was when he said he wanted to be in an induced coma because the pain was so bad.

I have to keep telling him its not your fault.

He has no life. His life has been crippled. Even wearing clothes hurts for him. He cant even put water on his skin because it feels like fire.

He cant do any sport because he cant sweat.

Its heartbreaking to see him go through this. I would do anything to fix this.

Sadly doctors havent found an effective treatment for Barneys condition and now his eczema has spread to his face.

Radio presenter Miranda said: After taking the new medication it looked like hed had acid thrown in his face.

We must have tried 50 different creams in the last year and every single one was like fire on his skin.

Were in this horrible position where nothing is working.

You can see its really got to him but hes brave and Im incredibly proud of him.

Currently Barney is on a daily dose of a steroid called Prednisolone but it has strong side effects, such as weight gain, which means its not sustainable.

The steroid has reduced the eczema on Barneys face but Miranda says hes totally reliant on the drug and still has a severe rash on his neck.

He also takes Dupilumab, a 24,000-a-year drug prescribed by the NHS, but its yet to prove effective.

Now Miranda is fundraising 20,000 for private treatment to properly diagnose Barneys condition and to find him a cure.

So far, shes raised 13,000 some of which was used to buy an air conditioning unit for Barney for the hot weather, when his condition worsens.

More information on the fundraising page can be found here.

Do you have a story to share?

Get in touch by emailing MetroLifestyleTeam@Metro.co.uk.

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When to Worry About a Rash in Adults – Healthline

Posted: at 5:23 am

Rashes can cause irritation and discomfort. Rashes in very visible places such as your hands or face might even cause embarrassment. Fortunately, most rashes are mild and not a cause for concern. You can generally treat a rash with over-the-counter (OTC) remedies.

However, there are rashes that a medical professional should look at. These rashes might be a sign of an infection, allergic reaction, or disease. You can read 12 common signs a rash might be a sign of something more serious below.

An area on your skin that is itchy, irritated, and swollen is called a rash. A rash can be raised, bumpy, blistered, or patchy.

Rashes can present differently depending on your skin tone. People with lighter skin often see rashes that are pink, red, or purple. People with darker skin might develop rashes that are white, gray, or darker than the surrounding skin.

Rashes can be caused by many things including:

Rashes are very common. Many types of rash are mild and can be treated with OTC medications. For example, contact dermatitis is a rash you get when your skin touches something that causes it to become itchy and irritated.

If youve ever gotten a rash from a new laundry detergent, lotion, or soap, your rash was likely contact dermatitis. A contact dermatitis rash will be inflamed and itchy. It will generally be contained to the part of your skin that touched the irritant.

Avoiding the item in the future and using an OTC anti-itch cream is normally enough to treat contact dermatitis.

Other common rashes in adults include:

Sometimes, a rash is a sign something serious is going on with your body. Its a good idea to keep an eye on any rash you develop and watch for these signs. Seek medical care if any of them develop.

A fever is a key sign that rash should be looked at by a doctor. It could be a sign of an allergic reaction. A fever along with your rash could also indicate an infection such as:

A rash that is spreading is another sign its time to seek medical care. A rash that is spreading quickly might be a medical emergency. Its best to go to an urgent care center or the emergency room if your rash is spreading rapidly.

If your rash is spreading slower but is spreading over your body, its still a good idea to get it looked at. It might be a warning that your rash is caused by an allergic reaction or an infection.

A painful rash should be looked at by a medical professional. It could be infected or a sign of conditions such as shingles.

Its best to also keep an eye on any rash that isnt painful but that is tender when you press on it. This could be a sign of infection, and youll want to have it checked out if it doesnt resolve after a day or so.

A rash that comes suddenly may be an allergic reaction to a medication. Sometimes, a rash can develop in the first few weeks after you start a new medication. Let a medical provider know about this side effect as soon as possible.

Its important to be careful when a rash is caused by an allergic reaction to mediation. This kind of reaction can lead to difficulty breathing and may become a medical emergency.

Sometimes rashes caused by sun exposure or poison ivy can blister. These rashes generally heal on their own in most cases.

However, unless youre sure your rash was caused by the sun or poison ivy, any rash that blisters should be looked at by a doctor. It could be a sign that your rash is a severe allergic reaction to a medication or caused by an autoimmune condition called pemphigus vulgaris.

Rashes damage the surface of your skin. This can make it easy for infections to develop, especially if you scratch the rash area. An infected rash should be looked at by a medical professional. Signs a rash is infected:

This is a medical emergency. Call 911 or seek care right away. A rash and difficulty breathing can be signs of a serious allergic reaction. This might happen when you eat or drink something youre allergic to.

A rash that looks like large purple patches or dark bruises can be a sign of a serious condition. It could be a warning sign of an infection spreading throughout your body or of a blood clotting problem. It could also indicate a condition called vasculitis that causes your blood vessels to become inflamed.

A medical professional can determine whats causing this rash and start treatment.

A rash with bruising or swelling around it might have been caused by an insect bite. Its a good idea to seek medical care if you notice this symptom. The bruises and swelling are a warning that that poison from the bite could be cutting off blood flow to the area.

A circular-shaped rash could indicate Lyme disease. Caused by ticks, Lyme disease normally causes a rash that resembles a bulls-eye and symptoms similar to the flu. Antibiotics are the primary treatment for Lyme disease, so youll need to visit a medical provider for a diagnosis and prescription.

A rash that persists for more than a week is worth getting looked at by a medical professional. There might be a reason your body is having trouble healing the rash. Plus, even if your rash is mild, a medical professional can give you tips to treat it at home.

Its a good idea to get any rash that is causing you to feel significant discomfort or concern checked out by a dermatologist or other healthcare professional. While it might be simple contact dermatitis, its still a good idea to consult a doctor.

Rashes are a common skin condition. Most rashes are temporary and clear up on their own. However, a rash can be a sign of something more serious.

Allergic reactions, infections, autoimmune conditions, and more can also cause rashes that need to be seen by a medical professional.

Rashes that occur along with trouble breathing, fever, lightheadedness, or nausea, are a medical emergency.

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Teen tells mum hed rather be put in an induced coma than suffer unbearable eczema – The Mirror

Posted: at 5:23 am

Barney has suffered from eczema since he was a toddler but now, it makes his skin so itchy that he often scratches himself raw and he is covered in blood.

Image: SWNS.com)

The mum of a teenager living with crippling eczema is desperately trying to find a cure for his skin condition.

Barney, 14, has asked to be placed in an induced coma to avoid dealing with his dry, cracked skin, which makes his body constantly feel as though its on fire.

Eczema is red, flaky and itchy skin, which will often crack and weep. The most common type of eczema is caused by allergies (atopic), but people may suffer from contact eczema (flare-ups after touching allergens such as nickel or rubber), discoid (which occurs in coin-shaped patches), or seborrheic (eczema of the scalp).

Although you may be genetically predisposed to eczema, it can only be set off by a trigger, which could be anything from nuts to dog hair, wool to cigarette smoke.

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Barneys case of the condition makes his skin so itchy that he often scratches himself raw, until he is covered in blood.

Barneys mum, Miranda Rae has told Metro of her dilemma, saying she wants to help her son to regain control of his life.

The teen is due to start Year 10 this month, but finds it excruciating to wear a school uniform.

Miranda, from Bristol, has attempted to bandage Barneys body while he is sleeping, to no avail. She said he had one day come into her room bleeding from head to toe, shaking, saying he couldnt believe what he had done to himself.

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The pain was constant, Miranda said, and Barney was frequently covered with cuts and puss.

While Barney had suffered from the skin condition since he was four years old, it was only last year that his condition began to deteriorate.

Now, wearing clothes hurt, while water and sweat touching his skin caused the boy excruciating pain.

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Miranda adds: The worst thing was when he said he wanted to be in an induced coma because the pain was so bad.

Its heartbreaking to see him go through this. I would do anything to fix this.

Doctors have not yet managed to find an effective treatment for Barneys condition, despite the family having tried dozens of different creams and medication over the past year.

But Miranda said they were in a horrible position where nothing was working. The eczema had now spread to the teens face, and Miranda said the situation really got to him.

The steroid Barney was currently on, Prednisolone, had strong side effects such as weight gain, which meant it was not sustainable as a long-term fix. It had helped the eczema on his face, but his mum said he is reliant on the drug, which has not fixed bad rashes on his neck.

He is also taking a 24,000-a-year drug called Dupilumab, which is prescribed by the NHS, but its yet to prove effective.

Desperate for a fix, Miranda is now fundraising 20,000 for private treatment, to properly diagnose Barneys condition and find him a cure.

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Teen tells mum hed rather be put in an induced coma than suffer unbearable eczema - The Mirror

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The A-Z of baby skin conditions the signs every parent needs to know (and tips to treat them)… – The Sun

Posted: at 5:23 am

IT can be scary when your baby comes up in a rash, bump or lumps.

Most of the time, skin conditions that affect babies are harmless and easily treated.

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They are also extremely common, as little ones have very sensitive skin which is still developing.

This A-Z skin bible, created by WaterWipes, gives the rundown on what to expect when you take your baby home.

You would think acne isnt something that hits until teenage years.

But baby acne is common and is thought to develop because hormones that aggravate skin glands are passed from the mum to baby via the placenta.

The babys own vomit and saliva can also aggravate the skin.

It usually develops on babies cheeks in the first few months of life. You might notice spots on your babys neck, back or chest.

In most cases the acne resolves on its own without treatment.

From port wine stains to blue-grey spots, birthmarks can come up anywhere and are usually nothing to worry about.

See your GP if one develops near the nose, eye or mouth; gets bigger, darker or lumpier; or is sore or painful.

You should see a doctor if your child has six or more cafe-au-lait spots or a large congenital mole from birth.

If a thick, crustly, oily or scaly patch covers your babys scalp, they may have cradle cap.

The harmless skn condition doesnt bother your baby. But could be there until they are a toddler.

Its not catching. But there are some things you should avoid doing, including picking the crust, using adult shampoos, soap, peanut oil or olive oil.

Baby and vegetable oil are suitable, as well as unperfumed baby shampoo and body washes.

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Contact dermatitis causes the skin to become itchy, blistered, dry and cracked. Lighter skin can become red, and darker skin can becomes dark brown, purple or grey.

It is most commonly caused by irritants such as soaps and detergents, solvents or regular contact with water.

Depending on what is causing it, there are steps you can do to manage it. See your GP to find out more.

It can lead to eczema.

Baby eczema often appears in the first year, and looks like patches of red, scaly skin that feel quite rough. It causes the skin to become itchy, dry and cracked.

The patches are often on the backs of the knees, elbows, cheeks, forehead and scalp.

Some things you can to help calm eczema include avoiding overwashing your baby (no more than three times a week), wearing cotton clothing, and avoiding perfumed products.

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It is normal for babies to scratch their faces and not something to worry about, unless there is a condition such as eczema.

To try and reduce them catching their skin, keep their nails trim, as they can grow quite fast.

You can use baby nail scissors or a nail file.

As babies start to move around more, it is very normal for them to get grazes and cuts.

As you would do with a child or adult, stop the bleeding, clean the wound and cover it with a plaster.

Speak to your GP if you have any concerns.

Hives are a sign of an allergic reaction. In babies, this could be to a certain food or an insect bite.

In babies and young children, up to four in five cases are triggered by an infection, such as a cold or flu

Hives cause raised red patches, which may be less noticeable on darker skin.

Its usually not serious. But call 999 if other symptoms are present including difficulty breathing, swelling of the lips and/or mouth, a rapid heart rate or clammy skin.

Impetigo is a skin infection that's very contagious, causing blisters and sores.

But its not usually serious and often gets better within 10 days with antibiotics.

You can help in the meantime by covering the sores with loose clothing or bandages, avoiding touching the sores, and keeping surfaces and shared toys or materials clean.

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Jaundice sounds like a scary condition but is actually quite common in babies (60 per cent) and is usually harmless.

It causes yellowing of the skin and eyes.

This is due to a buildup of bilirubin, a yellow substance, in the blood.

Bilirubin is produced by red blood cells - and newborns have more red blood cells.

A newborn will be checked for jaundice within 72 hours of birth and about five days lateral

This condition causes small bumps to appear on the skin, also seen in adults.

Keratosis usually presents as patches of small bumps on the arms, thighs or bottom, but they can appear in other places where hair follicles are.

It is a long-term skin condition, but with many people, the bumps go away as they get older.

Lumps are quite uncommon in babies and could be either a verruca or wart.

You can buy creams, plasters and sprays from pharmacies to treat warts and verrucas. But they may take a few months to clear up.

Warts do not cause any harm, but if your baby has one they may find it itchy and uncomfortable in some cases. Verrucas, also known as plantar warts, are more likely to be painful.

Other lumps in babies, include caput succedaneum which refers to swelling of an infant's scalp that appears as a lump or bump on their head shortly after delivery.

Nearly half of all newborns will have milk spots, which are tiny yellowish or white spots on the face.

Milk spots should clear up on their own, without treatment, in a few weeks. However, it's a good idea to keep your baby's face clean with warm water and gently pat dry the affected skin, don't rub.

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Nappy rash is very common and occurs because the material of the nappy rubs on the skin around the bottom and legs.

Make sure you are changing your babys nappy as soon as it becomes soiled or wet, and ensure their bottoms are cleansed well when changing.

But visit your GP if there are signs the rash is severe, including if it spreads beyond the nappy area or if there are sores that bleed.

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Oral thrush is a yeast infection thatoften appears as white creamy spots or patches that coat your baby's mouth, tongue and gums.

While it is only a mild infection, it can be uncomfortable for your baby and they could pass it on to the mums nipple.

If your baby is over four months old and has oral thrush, speak to your local pharmacists. But if your baby is under four months, speak to your GP first.

A baby born before 37 weeks is premature, and their skin may be more sensitive.

Even full-term babies have a weak skin barrier, so premature babies are likely to spend some time in hospital.

It is important to avoid chemicals, including fragrances, instead of choosing gentle products with minimal ingredients.

When you take home your baby, youll be full of questions on how to care for it.

When it comes to skin, avoid any ingredients that may irritate the skin, like harsh soaps or cleansers.

Stick to baby-friendly products.

A rash could be caused by chicken pox, teething, prickly heat, measles, or hand foot and mouth disease.

Most of the time, rashes are not something to worry about.

However, they can be the sign of something very serious.

If you notice your little one has a rash that spreads or they have other symptoms (such as a high temperature), difficulty breathing, or limp limbs you should call 999 or go straight to A&E.

If the rash doesnt fade when a glass is pressed against it, this could be meningitis.

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Babies have thinner skin than adults. This means it's more prone to irritation.

This can be worsened by changes in the weather, heating in your home, fragranced products, or excessive washing.

Dont wash your baby more than 2-3 times a week with warm water, and only for around five minutes.

A rash can come up when your baby is teething because they drool.

Typically the cheeks, chin and neck are affected - and your little one may rub its ears.

The best way to treat this is to keep your babys skin clean and dry by gently wiping or patting the saliva away.

Teething usually starts at around six to 12 months old and by three years old your little one should have all their milk teeth.

When you take your newborn home, it will have an umbilical cord stump.

For the first few weeks, its important to keep the area dry, before it falls off naturally, usually after two to three weeks.

It will then take another week or so for the belly button to form.

There may be some blood - but dont panic, just wipe it away. If there is a lot of blood or yellow pus, see your GP.

Vitiligo is a long-term skin condition where patches of skin lose their colour permanently. The patches are different in everyone.

It is most common on the face, hand, genitals and chest. It can also cause the hair or eyelashes to turn white or grey.

If your little one is under six months, they should not wear sun cream and should be kept completely out of the sun, kept in the shade and should wear hats/loose fitting clothes to protect their skin.

Wipes will come in handy for all sorts of things as you care for your baby - cleaning their face, wiping surfaces and your own hands.

But dont use any old wipes, as they could be full of harsh chemicals.

WaterWipes recommend their own product which has minimal ingredients, and therefore is delicate on the skin.

They are purer than cotton wool and water, the firm claims.

Founder Edward McCloskey created them when his newborn daughter suffered with severe nappy rash.

Who do you turn for when you need advice on your baby and their skin?

The NHS website has a wealth of information. You can also speak with your GP, a pharmacist, a health visitor or midwife.

Your midwife is your key point of contact during pregnancy and directly after the birth, followed by a health visitor.

A babys journey to eating solid food, and how they move food around their mouth, chew and swallow, can be a messy experience.

Weaning is when you start to introduce your baby to solid foods at around six months old.

Introducing new foods can also sometimes trigger allergies in babies, so introduce common allergy-trigger foods slowly and one at a time.

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The A-Z of baby skin conditions the signs every parent needs to know (and tips to treat them)... - The Sun

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Teen asked to be put in induced coma because of his eczema – Derbyshire Live

Posted: at 5:23 am

WARNING: Contains distressing images

A desperate mum is appealing for a miracle cure for her teen son's crippling eczema - which is so bad that he's asked to be placed in an induced COMA.

Miranda Rae, 50, said that son Barney, 14, feels like his skin is constantly on fire and has scratched himself until he's covered in blood to stop the itching.

The poor lad is due to start Year 10 this month despite finding it excruciating to even wear a school uniform over his cracked body.

Single mum Miranda said she's tried to bandage up Barney's skin to ease his pain but he can't help but tear the bandages off as he sleeps.

Miranda, from Bristol, said: "One night he came into my room and was bleeding from head to toe.

"He was shaking and said 'I can't believe I've done this to myself'.

"Now he's terrified of sleeping because he ends up scratching when he's asleep.

"He's bleeding with cuts and puss all the time. It's constant, there's no second of relief."

Barney has suffered from eczema since he was four but last October the condition deteriorated - forcing the teen to his lowest point.

Miranda said: "The worst thing was when he said he wanted to be in an induced coma because the pain was so bad.

"I have to keep telling him 'it's not your fault'.

"He has no life. His life has been crippled. Even wearing clothes hurts for him.

"He can't even put water on his skin because it feels like fire.

"He can't do any sport because he can't sweat.

"It's heartbreaking to see him go through this. I would do anything to fix this."

Doctors can't find a cure for Barney's condition and his eczema even spread to his face last June after he tried one suggested Emollient spray.

Miranda, a radio presenter, said: "After taking the new medication it looked like he'd had acid thrown in his face.

"We must have tried 50 different creams in the last year and every single one was like fire on his skin.

"We're in this horrible position where nothing is working.

"You can see it's really got to him but he's brave and I'm incredibly proud of him."

Barney currently takes a daily dose of a steroid called Prednisolone but its strong side effects - which have seen his waist balloon to 40 inches wide - meaning it's not sustainable.

The steroid has reduced the eczema on Barney's face but Miranda said he's totally reliant on the drug and still has a severe rash on his neck.

He also takes Dupilumab, a 24,000-a-year drug that the NHS agreed to prescribe to Barney once a fortnight after appeals from his mum and doctor.

But Miranda said the drug is yet to prove effective in battling the eczema.

She's is fundraising 20,000 for private treatment to properly diagnose Barney's condition and find him a cure.

Miranda has already raised 12,000 - some of which was used to buy an air conditioning unit for Barney for the hot weather, when his condition worsens.

The fundraising page can be found here.

For more stories from where you live, visit InYourArea.

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Shoppers Are "Blown Away" By the Huge Difference This Serum Makes in Wrinkles Overnight – Yahoo Lifestyle

Posted: at 5:23 am

Shoppers Say This French Retinol Is "Practically a Miracle" for Deep Lines and Large Pores

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Little known fact: For Whom the Bell Tolls has two meanings. One refers to Ernest Hemingway's novel, and the other, to everyone who's been shafted by beauty products that fail to deliver. There's nothing like spending money on a do-nothing cream that's inevitably tossed into a shadowy cabinet, and if you're trying to avoid that fate, the key is to stick with trusted brands and trusted ingredients, like a retinol from La Roche-Posay.

The French brand made its name with ultra-gentle essentials for stubborn eczema, acne, and sun protection both Kelly Ripa and Heidi Klum love La Roche-Posay's tinted sunscreen, which Klum dubs her "greatest beauty discovery." A bottle of the brand's Double Repair Hydrating Cleanser sells every two seconds, so the brand's definitely a crowd favorite, and its Redermic anti-aging line is just as revered.

"Miracle worker," writes one shopper of the results they saw in four days. "WOW. My laugh lines are disappearing right before my eyes." Others write that it gave them clear skin the likes of which they haven't seen in years, all from a few dots of the potent Redermic R Anti-Aging Retinol Serum.

La Roche-Posay Redermic R Dermatological Anti-Aging Treatment Intensive

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Shop now: $50; amazon.com

After searching for something to replace their prescription retinol when insurance stopped covering it, one shopper says Redermic "is definitely the winner" for similar results at a lower price. A single application produces a remarkable change: "After only wearing it overnight once, there was already a huge difference in redness reduction, softness, and wrinkle smoothing," comments a 46-year-old, adding that it also made creases more shallow and reduced rosacea. "I was blown away."

Reviewers a decade older see similar results from the creamy serum. "I'm almost 63 and don't have one wrinkle around my eyes. No one ever believes my age," one person writes. "You wake up looking five years younger, not kidding!" A few weeks of it diminishes dark spots, and long-term use develops even greater rewards; a 66-year-old at the sixth-month mark says that it significantly reduced their fine lines, and vastly improved "deep wrinkles." Those with sagging, uneven skin say it performed just as well, their skin left glowing, even, and smoother within days.

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The ingredients responsible? Two forms of retinol, emollient octyldodecanol, and adenosine. Speaking to the latter, Paula's Choice writes, "One of the particularly exceptional qualities of adenosine is that it's a natural component of the body, and its receptors have specifically been identified in skin cells, allowing for a direct connection and impressive effectiveness when applied topically.

In one study conducted by L'Oral, adenosine showed efficacy in as low as 0.1 percent concentration for improving deep wrinkles in the periorbital area (i.e. crow's feet) as well as glabellar frown lines (known as the 11s between brows)." La Roche-Posay is owned by L'Oral, so grain of salt, but impressive nevertheless.

The effects extend to acne and large pores: "After two weeks, I don't have a single noticeable blackhead anywhere. The acne that used to pile up over my temples is gone," one 45-year-old noted. "My friends are even starting to notice, asking if I quit smoking and drinking beer. The answer to that is no. I will buy this stuff as long as it is available."

Another shopper writes, "I received a compliment recently from a young man on how pretty my skin is. I haven't had a compliment on my skin since my 20s [and] I'm 55 years old." They're not alone; a different person writes that it erased their fine lines so well, their skin actually looks better than it did when they were in their 20s. Intrigued? Try the multitasking serum for yourself.

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Shoppers Are "Blown Away" By the Huge Difference This Serum Makes in Wrinkles Overnight - Yahoo Lifestyle

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