Category Archives: Eczema

University of Sydney researchers have discovered a new type of immune cell in skin that plays a role in fighting off parasitic invaders such as ticks, mites, and worms, and could be linked to eczema and allergic skin diseases. The findings have been published today in the journal Nature Immunology.

The team from the Immune Imaging and T cell Laboratories at the University-affiliated Centenary Institute worked with colleagues from SA Pathology in Adelaide, the Malaghan Institute in Wellington, New Zealand and the USA.

The new cell type is part of a family known as group 2 innate lymphoid cells (ILC2) which was discovered less than five years ago in the gut and the lung, where it has been linked to asthma.

Dr Ben Roediger, a research officer in the Centenary's Immune Imaging Laboratory said this was the first time such cells had been found in the skin, and they are relatively more numerous there.

"Our data show that these skin ILC2 cells can likely supress or stimulate inflammation under different conditions," he said.

"They also suggest a potential link to allergic skin diseases."

Head of the laboratory, Professor Wolfgang Weninger said: "There is a great deal we don't understand about the debilitating skin conditions of allergies and eczema, but they affect hundreds of millions of people worldwide. Dermal ILC2 cells could be the clue we need to start unravelling the causes of these diseases."

The Weninger lab, which has developed techniques for marking different cells of the immune system and tracking them live under the microscope, actually discovered the new dermal cells some years back.

"We just didn't know what they were," Dr Roediger said.

The Centenary researchers, however, suspected they might be associated with type 2 immunity, the part of the immune system that deals with infection by parasitic organisms. So they contacted Professor Graham Le Gros at the Malaghan Institute, one of the world's foremost researchers into type 2 immunity.

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New immune cells hint at eczema cause

Okato variable order sharemilker Anthony Neil has a lot on his mind.

Facial eczema on the farm where he is milking has killed four cows and has made half the 330-cow herd ill. It has all happened just as his partner, Nicole Beattie, is due to give birth.

The baby has yet to arrive. "It's waiting until things on the farm settle down," she said yesterday.

At least nine dairy cows in the Okato area have died of facial eczema this week.

Neil said almost half the herd he was milking had lost a lot of condition. "Hopefully they'll recover, but [the disease] could affect calving and cause milk fever next season."

He knew facial eczema would make skin raw or make cows' udders sensitive, but he had seen no symptoms. "It was full-blown eczema in two days. There was nothing I could do."

A count of 540,000 facial eczema spores on the farm last week rose to 770,000 by Tuesday. "That's insanely high," said Neil, who is Okato Young Farmers president. Spore counts above 50,000 are considered to be the trigger for the disease in unprotected stock exposed to that level for a length of time.

He had been putting full doses of zinc in the water for two months and half doses for the previous six to eight weeks. But water treatment was only 70 per cent effective and was insufficient when spore counts were extreme.

He is now spraying the pasture and hopes yesterday's rain will lower the spore count.

Neighbours had helped him administer zinc to the entire herd and to herds on nearby farms.

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Facial eczema risk 'insanely high'

Facial eczema has killed at least nine dairy cows in the Okato area of coastal Taranaki.

Six cows have died on one farm and about 12 are sick. On another farm one cow has died and clinical cases number about 18.

Okato vet Graeme Charteris said 770,000 facial eczema spores were recorded yesterday just hours after the count was 540,000.

Counts in the district were averaging 300,000 yesterday after being between 60,000 and 120,000 on Friday, Charteris said.

He's warning farmers the facial eczema season is not over.

"Rain and warmth are a hotbed for facial eczema spores," he said. "Farmers need to be vigilant with protection. Counts could stay high until well into May, so don't stop treatment."

This week's counts were significant and farmers needed to ensure their cows were receiving the right dose of zinc to combat facial eczema.

Zinc could be given as a drench, added to stock water supplies, or applied to pasture as a spray.

At such high numbers, zinc capsules were the most effective form of treatment at 95 per cent, while water treatment was about 70 per cent effective.

Spore counts above 50,000 are considered to be a trigger level for the disease for unprotected stock exposed to that figure for a length of time.

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Taranaki cows killed by facial eczema

CLn SportWash is the second product from TopMD to receive the Seal of Acceptance from the National Eczema Association.

Dallas, TX (PRWEB) April 11, 2013

The NEAs Seal of Acceptance, part of the organizations Eczema & Sensitive-Skin Education Program, is awarded to products intended for people with eczema. The designation is provided as a service to encourage and recognize product innovations that provide benefit to the quality of life for people with eczema and sensitive skin.

This is the second TopMD product to receive the designation; CLn BodyWash was awarded the Seal last December.

Were pleased to receive the National Eczema Associations Seal of Acceptance for a second time, said Dr. Azam Anwar, founder of TopMD. We are dedicated to improving the lives of children and adults living with eczema and sensitive skin disorders. In the sports arena, theres a huge need that were able to fill through CLn SportWash, and we hope the Seal gives athletes and families peace of mind to try SportWash as they search for solutions.

CLn SportWash was formulated with athletes in mind, as skin infections are very common in sports, especially those that involve body contact or shared equipment, spas or towels. Microbes and bacteria thrive in places like gyms and locker rooms, creating a new set of concerns for families, especially those already dealing with sensitive skin conditions.

The NEA Seal of Acceptance is only awarded to products intended for use by people suffering from eczema or severe sensitive skin conditions. The evaluated criteria include testing data on sensitivity, safety and toxicity, as well as ingredients, content and formulation data, to determine that it does not contain ingredients that should be avoided by people with eczema.

For more information about CLn SportWash, visit http://www.clnwash.com/cln-sportwash.html. For more about the NEA and its Seal of Acceptance, visit http://www.nationaleczema.org.

About TopMD Skin Care

Founded by Texas physicians, Azam Anwar, M.D., and highly regarded dermatopathologist Clay Cockerell, M.D., TopMD Skin Care released its premier product, CLn BodyWash, in the first quarter of 2012. As an over-the-counter, non-prescription product, CLn BodyWash is an innovative, non-irritating gel cleanser designed to effectively cleanse skin prone to eczema, acne and folliculitis. Developed by dermatologists, the cleanser has been clinically tested to be safe and effective in children (six months and older). CLn BodyWash can be used in the shower or bath head to toe and emulates the effectiveness of a bleach bath with greater convenience and portability. CLn BodyWash is currently sold in select physicians offices, online at http://www.clnwash.com and at select pharmacies.

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TopMD’s CLn® SportWash Receives National Eczema Association Seal of AcceptanceTM

Dr Rajesh Shah explaining role of homeopathy for Eczema treatment
Eczema and atopic dermatitis find good treatment using homeopathy, explains Dr Rajesh Shah, MD, director, Life force, who has treated patients from across th...

By: lifeforcehomeopathy

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Dr Rajesh Shah explaining role of homeopathy for Eczema treatment - Video

Curare, alleviare, prevenire l #39;eczema nelle fasi di remissione
Prof. Carlo Gelmetti, dermatologo, Ospedale Maggiore Policlinico, Milano.

By: FondationDA

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Curare, alleviare, prevenire l'eczema nelle fasi di remissione - Video

Eczema Relief - Rife Frequencies
You should feel relief fairly quickly with these frequencies (original Rife Preset), particularly when used with -Itching- and -Pain Relief- (also on this ch...

By: newtimer5

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Eczema Relief - Rife Frequencies - Video

DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/z64gwp/eczema_pipeline) has announced the addition of the "Eczema - Pipeline Review, H1 2013" report to their offering.

This report provides information on the therapeutic development for Eczema, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Eczema.

Eczema - Pipeline Review, Half Year is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- A snapshot of the global therapeutic scenario for Eczema.

- A review of the Eczema products under development by companies and universities/research institutes based on information derived from company and industry-specific sources.

- Coverage of products based on various stages of development ranging from discovery till registration stages.

- A feature on pipeline projects on the basis of monotherapy and combined therapeutics.

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Research and Markets: Eczema - Pipeline Review, H1 2013

Prebiotis supplements in infant formula may help to prevent eczema, but there is lack of evidence that the same is true for allergies, according to a new Cochrane review.

The systematic review of the evidence, published by The Cochrane Library, drew together data from four clinical studies involving a total of 1,428 children; finding that eczema was significantly reduced in children who were fed formula containing prebiotics.

However the review team, led by John Sinn from the University of Sydney in Sydney, Australia, revealed that the evidence for allergies was weaker - noting that the number of children who developed asthma was similar whether they were given formula with added prebiotics or without, while the one study looking at urticaria (hives) found that giving children formula containing prebiotics did not prevent any cases of the allergy.

Given these findings, it remains unclear whether the use of prebiotics should be restricted to infants at high risk of allergy or may have an effect in low risk populations, said Sinn.

Overall, we found some evidence that infant formula containing prebiotic supplements can help prevent eczema in children up to two years of age, he said. However, the quality of existing evidence is generally low or very low."

"More high quality research is needed before we can recommend routine use of prebiotics for prevention of allergy."

Prebiotic promise

Much research has suggested that the microbiota the bacterial ecosystem lining the gut - may play an important role in a child developing sensitivities to certain foods and allergens by regulating immune responses and determining how they will react to the same substances in later life.

Prebiotics are indigestible components of foods such as breast milk, fruit and vegetables that are known to stimulate the growth and activity of the beneficial strains of bacteria in the gut. They are distinct from probiotics which are cultures of live bacteria like those added to yoghurts and infant formula.

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Prebiotic prevention: Cochrane backs infant formula prebiotics for eczema - but not allergies

THERE is no cure for eczema (atopic dermatitis), but with proper skin care and diet, it can be controlled. However, the danger does not stop with eczema.

Pantai Hospital consultant paediatrician, clinical immunologist and allergist Dr Amir Hamzah Abdul Latiff says eczema will likely herald the arrival of its "comrade diseases" -- allergic rhinitis and asthma.

"This is known as the atopic march, whereby in a human's life trajectory, he or she may suffer from eczema during their infancy; then, asthma or allergic rhinitis and nasal airway inflammation may follow suit during their teenage days or well into adulthood."

He says although 80 per cent of adults may outgrow eczema naturally, it does not mean that they are fully cured.

"It's just dormant and has not been producing any reaction due to the adult avoiding possible eczema trigger factors," says Dr Amir Hamzah, who is also president of the Malaysian Society of Allergy and Immunology.

He adds that possible trigger factors include stress, food such as peanuts, seafood or dairy products, and environmental allergens such as dust mites.

On the causes of eczema, he says it is mainly because of hereditary factors and gene truncation mutation in a particular protein known as filaggrin.

The lack of this protein inevitably causes a severe form of dry skin and itchiness. This leads to reactions within the skin that further damage the barrier effect of the skin, making it easier for bacteria to penetrate the skin.

Besides hereditary reasons, Dr Amir Hamzah says an imbalance in the Immunoglobulin E (IgE), an antibody to protect against parasites, can also become a factor.

Gleneagles Kuala Lumpur allergy and immunology consultant Dr Kent Woo says modern studies show that Vitamin D deficiency may play a role in incidences of allergy and atopic dermatitis.

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Understanding causes of eczema from scratch