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Moreover, the Direct to Consumer (DTC) DNA Test Kits report offers a detailed analysis of the competitive landscape in terms of regions and the major service providers are also highlighted along with attributes of the market overview, business strategies, financials, developments pertaining as well as the product portfolio of the Direct to Consumer (DTC) DNA Test Kits market. Likewise, this report comprises significant data about market segmentation on the basis of type, application, and regional landscape. The Direct to Consumer (DTC) DNA Test Kits market report also provides a brief analysis of the market opportunities and challenges faced by the leading service provides. This report is specially designed to know accurate market insights and market status.

By Regions:

* North America (The US, Canada, and Mexico)

* Europe (Germany, France, the UK, and Rest of the World)

* Asia Pacific (China, Japan, India, and Rest of Asia Pacific)

* Latin America (Brazil and Rest of Latin America.)

* Middle East & Africa (Saudi Arabia, the UAE, , South Africa, and Rest of Middle East & Africa)

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Table of Content

1 Introduction of Direct to Consumer (DTC) DNA Test Kits Market

1.1 Overview of the Market1.2 Scope of Report1.3 Assumptions

2 Executive Summary

3 Research Methodology

3.1 Data Mining3.2 Validation3.3 Primary Interviews3.4 List of Data Sources

4 Direct to Consumer (DTC) DNA Test Kits Market Outlook

4.1 Overview4.2 Market Dynamics4.2.1 Drivers4.2.2 Restraints4.2.3 Opportunities4.3 Porters Five Force Model4.4 Value Chain Analysis

5 Direct to Consumer (DTC) DNA Test Kits Market, By Deployment Model

5.1 Overview

6 Direct to Consumer (DTC) DNA Test Kits Market, By Solution

6.1 Overview

7 Direct to Consumer (DTC) DNA Test Kits Market, By Vertical

7.1 Overview

8 Direct to Consumer (DTC) DNA Test Kits Market, By Geography

8.1 Overview8.2 North America8.2.1 U.S.8.2.2 Canada8.2.3 Mexico8.3 Europe8.3.1 Germany8.3.2 U.K.8.3.3 France8.3.4 Rest of Europe8.4 Asia Pacific8.4.1 China8.4.2 Japan8.4.3 India8.4.4 Rest of Asia Pacific8.5 Rest of the World8.5.1 Latin America8.5.2 Middle East

9 Direct to Consumer (DTC) DNA Test Kits Market Competitive Landscape

9.1 Overview9.2 Company Market Ranking9.3 Key Development Strategies

10 Company Profiles

10.1.1 Overview10.1.2 Financial Performance10.1.3 Product Outlook10.1.4 Key Developments

11 Appendix

11.1 Related Research

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Direct to Consumer (DTC) DNA Test Kits Market Growth by Top Companies, Trends by Types and Application, Forecast to 2026 - Cole of Duty

Postdoctoral fellows Jenny Hamilton and Enrique Shao with an automated liquid-handling robot (Hamilton STARlet) that will be used to analyze swabs from patients to diagnose COVID-19. Hamilton and Shao volunteered to train to become CLIA certified so as to process patient samples. When analyzing real samples from patients, they would be wearing full personal protective equipment (PPE), including mask, face shield, gown and gloves. Photo: Max & Jules Photography/UC Berkeley

What happens when you combine a viral pandemic, an empty laboratory and a bunch of biologists whove been forced to put their regular work on pause?

In a matter of days, a UC Berkeley science building has converted to a COVID-19 test processing center, with researchers hoping to enable up to thousands more coronavirus tests per day in the East Bay.

The Innovative Genomics Institute at Berkeley Way and Oxford Street founded by Jennifer Doudna, co-developer of gene-editing technology CRISPR houses robots that will process samples from nearby medical centers and return the results in 12-24 hours instead of the usual several days, scientists say. The initiative is set to begin processing samples from UC Berkeleys Tang Center by the end of the week, but the researchers hope to expand the effort to other medical clinics in the region too.

We put in place a robotic pipeline for doing thousands of tests per day, with a pipeline for managing the data and getting it back to clinicians, said Doudna in a statement from IGI. Imagine setting that up a process that would normally take months to years in a couple of weeks. Its really extraordinary and not something Ive ever seen in my career.

The initiative is launching as reports abound of shortages and delays at every point in the coronavirus testing process across California and the United States. The city of Berkeley does not know how many people in Berkeley have been tested for the virus because, until a recent order, labs were only required to report positive results.

The IGI initiative will use a common technique called RT-PCR, which enables the detection of viral RNA in samples.

After UC Berkeley shuttered its labs and the novel coronavirus began spreading throughout the area, many scientists were hoping to apply their expertise to the local mitigation effort. About 800 faculty, graduate students and community members immediately volunteered to help out with the Berkeley effort, according to IGI.

My own research is shut down and theres not very much I can do other than stay in my home, said Ph.D. student Holly Gildea, who early in the effort put out a Bay Area-wide call for chemical substances needed to process the samples. Someone on Twitter compared this to being on a plane andsomeone asking for doctor finally Im useful.

Around 30 people mostly PhD students and postdoctoral researchers are currently being trained to oversee the process and babysit the robots, said Jenny Hamilton, postdoctoral researcher.

The volunteers were selected for their experience working with unsafe materials people who have the training to do clean practices and people who have the skillset needed, Hamilton said.

One UC Berkeley Ph.D. student who asked not to be named, however, said she was concerned that this front-line work is being done by volunteers instead of the initiative paying the skilled researchers.

Although IGI will receive samples after theyre collected at the clinic, the initiative will also supply Tang and other medical centers with the tubes and swabs they need to conduct the tests, aiming to significantly increase their testing capacity. The critical items are in short supply these days, so the Berkeley scientists have spent the past week or so seeking out products from non-traditional distributors around the world. They had to ask health care workers whether theyd be willing to use the slightly different products than theyre used to, but they were largely eager to accept any new testing materials, Hamilton said.

Everything in this process is limiting, she said. The major thing weve been doing in the past week is to secure a supply chain.

Revised guidelines from federal health authorities and Gov. Gavin Newsoms emergency declaration also permitted expedited approval for the initiative, according to the IGI statement.

The Berkeley researchers are working with UC San Francisco and the Chan Zuckerberg Biohub on the sample processing work. The initiative was also inspired by similar work being done at the University of Washington, Hamilton said.

The effort is also getting underway just asthe Berkeley Lab (not located in the IGI building) reported its first employee who tested positive for COVID-19. There is no indication that he got the virus while at work, however, and the lab stressed that cases are likely across all workplaces.

Hamilton said there will only be a few people in the IGI lab at a given time, always practicing social distancing.

Im much more concerned about someone catching SARS-CoV-2 at Berkeley Bowl than I am about anyone being exposed from one of these samples, she said.

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UC Berkeley lab pivots from editing DNA to processing COVID-19 tests - Berkeleyside

By The Associated Press

LAFAYETTE A motorist who was killed in a fiery highway collision with a truck hauling a load of grain will have to be identified through a DNA test, an Indiana coroner said.

Investigators believe they know the identity of the pickup truck driver who died in Wednesdays crash on U.S. 231 near Lafayette, but they must be positive before releasing the victims name, Tippecanoe County Coroner Donna Avolt said.

Relatives of the suspected crash victim, who was traveling in a pickup with an out-of-state license plate, are aware of the likely outcome of the DNA test, Avolt told the Journal & Courier. She said Thursday that the DNA test results will take a few days to complete.

The Tippecanoe County Sheriffs Office said the pickups driver turned in front of a semi hauling grain while attempting to turn left Wednesday afternoon along U.S. 231 onto Veterans Memorial Parkway, just southwest of Lafayette.

The semi's 75-year-old driver wasn't injured in the crash, but the pickup burst into flames after being dragged about 100 yards (about 90 meters) at the crash scene, located some 60 miles (96 kilometers) northwest of Indianapolis.

See more here:
Coroner: DNA will ID victim of fiery collision - The Herald

The virus that causes COVID-19, called SARS-CoV-2, shown here in an electron microscope image, can trigger severe cases of infection in some younger patients. Studying them could help scientists pinpoint genetic mutations that make people more susceptible to the disease. Credit: NIAID-RML

A new international project aims to enroll 500 COVID-19 patients to search for genetic mutations that make some people more vulnerable to severe infection.

Howard Hughes Medical Institute (HHMI) scientists are joining many of their colleagues worldwide in working to combat the new coronavirus. Theyre developing diagnostic testing, understanding the viruss basic biology, modeling the epidemiology, and developing potential therapies or vaccines. Over the next several weeks, we will be sharing stories of some of this work.

Hundreds of clinicians worldwide are banding together in an effort to study some types ofseverecases of the new coronavirus disease.

The project, led by Howard Hughes Medical Institute (HHMI) Investigator Jean-Laurent Casanova at The Rockefeller University, seeks to identify genetic errors that make some younger patients especially vulnerable to the virus that causes COVID-19, the infectious respiratory illness also known as coronavirus disease 2019.

Casanova aims to enroll 500 patients internationally who meet three broad criteria: theyre less than 50 years old, have been diagnosed with COVID-19 and admitted to an intensive care unit, and have no serious underlying illnesses, such as diabetes, heart disease, or lung disease.

By studying these patients DNA, scientists may pinpoint genetic mutations that make some people more susceptible to infection. Such information could one day help doctors identify people who are most at risk of developing severe coronavirus disease, says Casanova, a pediatrician at Rockefeller. It could also offer clues for scientists searching for new therapeutics. For example, if patients cells arent making enough of a particular molecule, doctors may be able to offer a supplement as treatment.

That day may still be years away. This is not a short-term effort, Casanova says. Some scientists have hypothesized that COVID-19 might be a seasonal illness, with infections ebbing in the spring and summer, and then returning in the fall. But Casanovas team is optimistic. They have already begun enrolling patients and have started sequencing their exomes spelling out all of the DNA letters in every gene in a persons genome. Were going to try to find the genetic basis of severe coronavirus infection in young people.

Late last year, when the first coronavirus infections began cropping up in China, Casanova started reaching out to his colleagues there. Though the most severe cases seemed to concentrate among older adults and those with other conditions, Casanova was interested in the outliers kids and young adults hit hard by the illness who didnt have any of the usual risk factors, such as age or underlying illness.

His team kicked off a new project to study these mysterious cases, and in January just weeks after the Wuhan outbreak began enrolling patients. Clinicians mailed patient blood and DNA to his lab, and researchers there and elsewhere began processing samples the first steps needed for scientists to peer into patients genomes. Now, the project is global, and Casanova is collaborating with scientists and healthcare workers from Europe to Africa, Asia, and Oceania.

Hunting for the genetic underpinnings of severe infectious diseases is nothing new for Casanovas team. What were doing with coronavirus is what my lab has been doing for 25 years with other infections, he says.

They look for weak spots in peoples immune systems small genetic changes that make people more vulnerable to disease. His group has previously searched the genomes of patients infected with viruses, bacteria, fungi, and even parasites. The infection closest to COVID-19 his team has studied is severe influenza pneumonitis, for which theyve discovered three genetic links. Theyve also identified specific genetic errors that can predispose patients with herpes to viral encephalitis. And theyve found that children with mutations in an immunity gene called IFN-gamma are vulnerable to the bacteria that cause tuberculosis. These children make low levels of the IFN-gamma protein, which is critical for fighting off bacterial infections.

Casanovas team has put these findings to use clinically. For example, the researchers have shown that tuberculosis patients with these genetic errors can benefit from treatment with IFN-gamma. Hes hoping to identify problematic genes in patients with severe coronavirus infection that can bring similar clinical gains. These genes could tell scientists which cellular defenses are crucial for warding off COVID-19 and pave the way for understanding whether such defenses are derailed in older adults or patients with an underlying medical condition.

In the US and around the world, severe coronavirus disease seems to hit older patients hardest, though scientists have reported some country-to-country variation. As of March 29, more than 122,000 confirmed and presumptive positive cases have been reported in the US. Fatality has been highest in people over 85 years old, according to a recent report from the Centers for Disease Control and Prevention (CDC). Though young people may be more susceptible than scientists once suspected,the older you are, the higher the likelihood you have a severe form of the disease, Casanova says.

Last week, Rockefeller closed all labs except those working on the coronavirus, and Casanova whittled his team to a skeleton crew of about eight people down from 35 who rotate so there is only one person per room at a time. He and his lab members are following CDC recommendations, and taking protective measures to keep themselves and others safe, including social distancing, washing hands, and disinfecting surfaces. Theyve also taken to Twitter to get the word out about their work. A tweet posted from Casanovas lab last week about recruiting new patients to their study has since been retweeted more than 400 times.

Soon, theyll be testing their genetic theory on a pandemic thats occurring in real time. Im grateful weve been able to start this new project so quickly, he says. God willing, it will be of clinical use in two or three years.

Read more here:
Clues to COVID-19 Treatment From DNA of Patients With Severe Forms of Coronavirus Disease - SciTechDaily

In the summer of 2013,Massachusetts authorities announced thatthey had finally identified the serial killer behind one of America's most terrifying cold cases.

They pointed to Albert DeSalvo, a long-deadconvicted rapist.DeSalvo had actuallyconfessed to the murders, but policehad dismissed him as a fraud.

So, why were investigators now so sure thatthey had really solved the mystery ofthe Boston Strangler?

Former LAPD detective and Fox Newsforensic and crime scene expertMark Fuhrmanwent back over the evidence and came to his own conclusionsin Fox Nation's"The Fuhrman Diaries."

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"Between 1962 and early 1964, there was a string of 13 murders in Boston," narrated Fuhrman."They were all females. They were all rapes. They were all murders with a ligature usually acquired within the residence."

However, there was nearly no discernable evidence left at the crime scenes and it was difficult for investigators to determine a pattern to the murders.The ages of the victims ranged from 19 to 85 years old.

"The victimology really created a problem for the police," noted Furhman. "We can't say that he's targeting people. ... They didn't know each other."

"The horrifying crimes rattled police almost as much as the public, but no one could catch him," said Furhman.

Then in 1965, a break in the case. A prisoner named Albert DeSalvo reportedly confessed to his cellmate that he was the Boston Strangler.DeSalvo was in prison for another string of violent rapes, but he didn't kill any of his victims in those heinous crimes.

In another bizarre twist,DeSalvo did not appear to have any detailed knowledge of the murders.

"During criminal investigations, detectives often keep certain pieces of evidence from the public to ensure that during interrogations, there are things only the suspect would know," explained Fuhrman.

5 TRUE CRIME SHOWS TO BINGE-WATCH ON FOX NATION

"Albert DeSalvo couldn't recall several crucial details about the crimes he supposedly committed," Fuhrmancontinued, "And in some cases, he got the cause of death, time of death and body position entirely wrong."

Psychiatrists evaluated DeSalvo, and they couldn't come to a conclusion either -- one doctor diagnosed him with multiple personality disorder, another disagreed.

Investigators eventually dismissed DeSalvo's confessionas the ravings of a loudmouth. He was never charged with the Boston Strangler murders and in1973he was stabbed to death by fellow inmates.

The cases laid dormant for decades until 2013 whenDeSalvo's name was again splashed across the headlines.

DNAwas recovered from semen found in decades-old evidence from the murderof 19-year-old Mary Sullivan. The genetic materialwas cross-checked against the DNA of one of DeSalvo's living relatives and finally, police had concrete evidence.

UNDERCOVER AGENT WHO TOOK DOWN NOTORIOUS SERIAL KILLER SPEAKS OUT

"This marker was proof that the nephew was related to the person that deposited the semen in the rape victim," said Fuhrman. "So once they had that, they exhumed the body of Albert DeSalvo and took a direct DNA test. And he was, in fact, the person that left a semen sample in Mary Sullivan the day that she was raped and murdered."

DeSalvo was conclusively linked to the murder of Mary Sullivan, but not the other 12 murders.Massachusetts Attorney General Martha Coakley alluded to this fact in a news conference in 2013.

"This leaves no doubt that Albert DeSalvo was responsible for the brutal murder of Mary Sullivan," she said, "and most likely that he was responsible for the horrific murders of the other women he confessed to the killing."

The other unresolved issue was that DeSalvo did not exhibit any knowledge of the crime scenes, but Fuhrman has an answer for that. Hebelieves that DeSalvo could have been the killer -- and not even known it.

"I think Albert DeSalvo did them all --he did all 13 victims of the Boston Strangler -- and I also believe that Albert DeSalvo had multiple personalities," said Furhman.

"If he had multiple personalities, he might not know unless that person is present during that interrogation or interview or statement that he is, in fact, remembering that exact moment," concluded Fuhrman. "I believe he did all of them. I just don't believe Albert knew he did."

To watch more of"The Fuhrman Diaries,"go to Fox Nation and sign up today.

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Fox Nationprograms are viewable on-demand and from your mobile device app, but only for Fox Nation subscribers. Go toFox Nationtoday to start a free trial and watch the extensive library from Tomi Lahren, Pete Hegseth, Abby Hornacek, Laura Ingraham, Ainsley Earhardt, Greg Gutfeld, Judge Andrew Napolitano and many more of your favorite Fox News personalities.

Read more from the original source:
Did DNA evidence identify the real Boston Strangler? - Fox News

Drake has revealed he had two DNA tests done before he stunned the world on Monday by sharing the first pictures of his adorable son Adonis.

The rapper - who initially kept his two-year-old child's birth a secret - shared a string of photos to Instagram showing off his blue-eyed, blonde curly-haired boy for the first time.

Drake, 33, went viral after rapping on the 2018 track March 14: "I wasnt hiding my kid from the world, I was hiding the world from my kid."

During an interview with Rap Radar which was released in December last year, Drake said he had to get DNA tests for him to be sure he was his child.

To be honest with you, I did a DNA test for my son and it came back to us and it said the DNA test got ruined in transit and they couldnt be 100 percent sure that that was my son or not, he said.

So, I was in a really weird pending situation where I didnt want to go tell the world that that was my son and it wasnt.

Drake alluded to his sons pale skin, blue eyes and blond hair and laughed: If you see my son you understand why.

Hes a stunning child you know, with the brightest blue eyes and at the time I was like I dont know.

It actually wasnt until a week before the album came out that I got confirmation that that was definitely my son.

The rapper then revealed: It took me two more solid [DNA] tests with two different companies.

Former adult movie star Sophie welcomed their son in October 2017.

In 2018, rapper Pusher T released a diss track entitled The Story of Adidon, in which he claimed Drake was hiding a secret child with a porn star.

Having initially keeping the news a secret, Drake confirmed he had fathered a child from a brief fling and opened up about fatherhood on his 2017 album Scorpion.

The rappers mindset appears to have changed as he posted the snaps and gushed over his toddler who he is currently isolating from separately due to the coronavirus pandemic.

Go here to see the original:
Drake demanded two DNA tests for his son before proudly showing him off to the world - Mirror Online

This article originally appeared on VICE AU.

Just before large gatherings were banned due to coronavirus, but after it hit the news, I attended a Mind, Body, Spirit convention in Sydney. As expected, it was full of clairvoyants and generalist psychics. But there were also a lot of people describing themselves as "medical intuitives".

According to various sources, so-called medical intuition involves reading and gathering "energetic information" from the body, in order to heal it. One such practitioner and speaker at the convention was 60-year-old Julie Lewin (pictured above), who told the crowds she could create the perfect DNA to protect you from coronavirus.

Julie would later explain to me that scientific evidence just isn't her thing: "It doesnt matter to me whether it's scientifically proven to be true," she asserted. "Its that I believe it to be true.

For the record, Im no psychic groupie; Im writing a book examining psychics' unchecked power. So this was research. But I was intrigued by Julies grand claim, and called her at home in Queensland to find out more.

Julie at home in Queensland. Image supplied.

I feel and see inside peoples bodies," Julie told me, when asked how she operates as a medical intuitive. "A movie in my mind plays, so I can see whats happening.

Julie has been doing this work since she was 25, when a psychic told her she had a gift. Prior to that she was in corporate life, and among other things ran her own secretarial business. These days she makes a living by running retreats, where she teaches her methods for $997 AUD. She believes everyone has intuition and can learn the techniques to heal themselves.

"Medical intuitives genuinely believe they have a magical gift," says Richard Saunders, former President of Australian Skeptics. "Its largely to do with the constant positive enforcement they get from clients, who are believers to begin with. They surround themselves in a bubble of people who believe the same things. In better times these people slip under the radar, but in times of national emergency they really should be scrutinised, named and shamed."

Trained doctors aren't having it, either. Dr Brad McKay, a Sydney GP (and former host of TV show Embarrassing Bodies) told VICE: Hearing people talk about medical intuition reminds us how important it is to get a formal education."

Look," she adds, "I dont understand the science of it too much, but its like a light switch turning on and off. The one thing I don't do is really get into the science of stuff. I use my intuition and do the visualising, because then I get an outcome."

According to Julie, humans have 20 codons switched on and four that are switched off, and to create immunity from coronavirus we need to have all 24 switched on. How do we do that? I don't feel comfortable giving you the technique, but its a visualisation process where basically youre turning them on she says. But its better they listen to my voice guiding them through that process than seeing it written down.

I checked, and codons form a unit of genetic code in DNA. Humans have 20 different amino acids, and 64 possible codons. Julie says she regularly turns on "all 24" of her own codons through visualisation techniques that help her recover faster from conditions like pneumonia. Its like when I was flying to Sydney for that event she tells me. I noticed two codons werent quite switched on, so I switched them on.

I ask Dr Brad McKays for his thoughts. A visualisation process might earn you high points on a Scrabble board, he says, but isnt going to switch your codons off or on.

In addition to her claims that she can switch codons on and off for her clients, Julie also advises them to keep out of polarity. When I ask her what polarity is she says its like Hitler. He polarised people. They loved him or hated him. Staying out of polarity is keeping your bodys charge zennot too high or low.

Could this all be the placebo effect, I ask her? Absolutely she responds. I think our mind is actually the root of many things.

To find out if the techniques of medical intuitives differ on coronavirus, I also spoke to Catherine Carrigan from Atlanta, Georgia in the US. Catherine describes herself as a "Medical Intuitive Healer" and says she uses her intuitive gifts to read whats happening in your body, energy system, emotions, mind and soul.

Like Julie, Catherine claims to be able to help with immunity against Covid-19. I can help you understand whatll make you strong enough to survive, she explains, listing 24 ways she boosts her clients immune systems naturally, which include stop using the microwave, cultivate positive emotions through regular prayer, and consider liquid silver rather than antibiotics." Catherine's guides are her angels, who tell me we are living through a very dangerous time".

Catherine from Atlanta, Georgia in the US. Image supplied.

So who exactly is going to the likes of Julie and Catherine for their unproven claims, and why? Julie put me in touch with a client, 53-year-old Louise Kelly. Louise is a physiotherapist from Victoria, Australia. When her husband, Al, fell from the house roof four years ago, he catapulted face-first onto concrete and had seven fractures in his spine, skull, nose and jaw. He also had whiplash of the spinal cord. From the ambulance, Louise called Julie.

She said to channel green emerald light through him, Louise tells me. With one hand holding the phone, the other cradled his head and worked on him, she says, while Julie claimed to be doing the sameby remote.

Al was in a neck brace for eight weeks and had to sleep in a chair till he was recovered, five months later. But Louise insists this green-light visualisation had an effect. As an experienced therapist of 30 years, Ive never seen anyone heal as quickly from such a severe accident," she says. "Ten days later, his facial skin was almost completely healed, and he was off his pain medication. He got out of bed on Sundayit happened on Thursday.

Julie's clients, Louise and Al. Image supplied.

Does she tell this story to many people? No. For lots of people its too weird, too way out there, she says. But honestly, its a resource we all have and dont use. Theres so much we dont know.

This knowledge gap should be filled with research-backed knowledge, says Dr Brad McKay. Not intuition. That especially applies to our current situation. Scientists are working hard to find a cure and vaccine to protect us all against coronavirus," he says. "Hearing someone claim to boost your immunity against this potentially lethal virus is insulting to the researchers working day and night to provide us with real solutions.

My intuition tells me the experts aren't buying it.

Gary Nunn is a freelance journalist. Reach him on Twitter: @garynunn1

Excerpt from:
The 'Medical Intuitives' Promising to Protect Your DNA Against Coronavirus - VICE

A virus is a microscopic package of genetic material surrounded by a molecular envelope. The genetic material can be either DNA or RNA.

DNA is a two-strand molecule that is found in all organisms, such as animals, plants, and viruses, and it holds the genetic code, or blueprint, for how these organisms are made and develop.

RNA is generally a one-strand molecule that copies, transcribes and transmits parts of the genetic code to proteins so they can synthetize and carry out functions that keep organisms alive and developing. There are different variations of RNA that do the copying, transcribing and transmitting.

Some viruses such as the coronavirus (SARS-Cov2) only contain RNA, which means they rely on infiltrating healthy cells to multiply and survive. Once inside the cell, the virus uses its own genetic code RNA in the case of the coronavirus to take control of and reprogramme the cells so that they become virus-making factories.

In order for a virus like the coronavirus to be detected early in the body using real time RT-PCR, scientists need to convert the RNA to DNA. This is a process called reverse transcription. They do this because only DNA can be copied or amplified which is a key part of the real time RT-PCR process for detecting viruses.

Scientists amplify a specific part of the transcribed viral DNA hundreds of thousands of times. Amplification is important so that instead of trying to spot a minuscule amount of the virus among millions of strands of genetic information, scientists have a large enough quantity of the target sections of viral DNA to accurately confirm that the virus is present.

Go here to see the original:
How is the COVID-19 Virus Detected using Real Time RT-PCR? - International Atomic Energy Agency

On May 6, 1993, 8-year-olds Stevie Branch, Michael Moore and Christopher Byers were found nude and hogtied in a West Memphis, Arkansas, bayou.

Their bodies and clothes had been jammed into the muddy ground with sticks, and their bikes were found on either side of a pipe bridge not far from the crime scene.

The boys had been so badly mutilated that investigators believed they had been killed in a Satanic ritual, and they soon arrested three outcast teenagers Damien Echols, Jason Baldwin, and Jessie Misskelley, Jr. and charged them with the murders.

The so-called West Memphis Three were tried and convicted of the slayings, but they continued to proclaim their innocence from behind bars, and a series of documentaries drew critical attention to the case and suggested the teens were the victims of Satanic Panic, a fear that Satanism would infect society.

While their appeals were repeatedly denied, a new set of DNA testing in 2007 revealed that no genetic material taken from the crime scene was a match to Echols, Baldwin or Misskelley, according to court documents obtained by Oxygen.com.

Four years later, they reached a deal with prosecutors and were released from prison after agreeing to an Alford plea, which allowed them to maintain their innocence while admitting the prosecution had enough evidence to convict them.

Although the men have been free for the past decade, they are still technically convicted killers, and it remains unclear who is responsible for the deaths of Branch, Moore and Byers.

Theres still that sense that something aint right. Things havent been finished. I just want my name back, and I want justice in this case, Baldwin told investigator and host Bob Ruff in the documentary special The Forgotten West Memphis Three, streaming now on Oxygen.

To potentially uncover new evidence in the case, Ruff is hoping to have the crime scene evidence including the bikes, sticks and clothing re-tested with M-Vac, a wet-vacuum DNA collection system that can gather 200 times more DNA sample compared to swab testing.

DNA testing was very limited back at the time of the trial in 1993. There was no such thing as touch DNA and so Im hoping that this new M-Vac technology may be the key to unlocking evidence thats been there this whole time, Ruff said.

In order to gain access to the evidence, however, Ruff and his team need the consent of district prosecuting attorney Scott Ellington. While Ellington was not in office during the original trials, he was throughout their appeals, and he was the one who ultimately approved the Alford plea that freed the West Memphis Three.

Following their release, Ellington pledged he was not abandoning the case.

It would be a dereliction of my duties not to review credible evidence thats been presented, and so we have to do that, Ellington said in a 2012 interview that was also featured in The Forgotten West Memphis Three.

As of now, Ruff and his team say theyve been unsuccessful in their attempt to contact Ellington, even though they have the support of Echols, Baldwin, Misskelley and victims family members, including Branchs mother, Pam Hicks, and Byers brother, Ryan Clark.

Ruffs hope is to finally figure out who murdered Branch, Byers and Moore and give the people involved some closure.

"There were a lot of victims. Many people had their lives completely and absolutely destroyed by this case," Echols told Ruff in The Forgotten West Memphis Three.

Although both Echols and Hicks said they were not surprised by the states lack of response, they continue to support Ruff in his fight for justice.

I met with Scott Ellington and, you know, all of them. Ive been from A to Z. Im the mother, and they wont even let me have access to anything. I want finally to be able to say that its over. But Im not giving up. Ive got too much hope and too much to live for, Hicks said.

Ruff has also vowed to exhaust every single possible avenue and effort to try to figure out who killed these boys.

The only way that were ever going to be able to solve this case definitively is gonna have to be through science and DNA testing. At this point, the balls in the court of Scott Ellington. So this is all gonna come down to whether Scott Ellington wants to find the truth or not because we have the technology to find it, Ruff said.

To hear more from those involved in the case, watch The Forgotten West Memphis Three, streaming now on Oxygen.com.

Crime Time is your destination for true crime stories from around the world, breaking crime news, and information about Oxygen's original true crime shows and documentaries. Sign up for our Crime Time Newsletter and subscribe to our true crime podcast Martinis & Murder for all the best true crime content.

Continued here:
Could New DNA Testing Fully Exonerate The West Memphis Three? - Oxygen

- Subsidiary of Global Biopharmaceutical Company to Evaluate Linear DNA as Replacement for Plasmids for CAR T Applications -

Applied DNA Sciences Inc. (NASDAQ: APDN) ("Applied DNA" or the "Company") a leader in Polymerase Chain Reaction (PCR)-based DNA manufacturing that enables diagnostics, pre-clinical nucleic acid-based therapeutic drug candidates, supply chain security, anti-counterfeiting and anti-theft technology, announced today that it has shipped two CAR T amplicons proprietary to the biologics subsidiary of a U.S.-based, global biopharmaceutical company. The customer is one of nearly two dozen development customers in various stages of evaluating the use of linear DNA manufactured by the Company.

"We see a steady flow of interest for our LinearDNA manufacturing platform from customers with gene and redirected-cell therapies. Securing development customers is the first step in our LinearDNA commercialization strategy that offers a path to higher and recurring revenues as customers validate linear DNA as a viable alternative to plasmid DNA. We expect some customers will license our intellectual property to enable the optimal performance of their therapeutic," said Dr. James Hayward, president and CEO of Applied DNA. "I am especially proud of our team during this coronavirus outbreak who continue to prioritize our work on COVID-19-related therapies and diagnostics, as well as deliver linear DNA to customers without interruption. In the coming weeks and months, we expect to continue our work with all therapeutic customers to optimize LinearDNA for their unique therapeutic applications."

LinearDNA is Applied DNAs branded platform for large-scale DNA manufacture by PCR.

About Applied DNA Sciences, Inc.

Applied DNA is a provider of nucleic acid technologies that enable diagnostics, pre-clinical nucleic acid-based therapeutic drug candidates, supply chain security, anti-counterfeiting anti-theft technology and product genotyping.

Visit adnas.com for more information. Follow us on Twitter and LinkedIn. Join our mailing list. Common stock listed on NASDAQ under the symbol APDN.

LinearDNA is a trademark of Applied DNA Sciences, Inc

Forward-Looking Statements

The statements made by Applied DNA in this press release may be "forward-looking" in nature within the meaning of Section 27A of the Securities Act of 1933, Section 21E of the Securities Exchange Act of 1934 and the Private Securities Litigation Reform Act of 1995. Forward-looking statements describe Applied DNAs future plans, projections, strategies and expectations, and are based on assumptions and involve a number of risks and uncertainties, many of which are beyond the control of Applied DNA. Actual results could differ materially from those projected due to the possibility of a failure to make timely payment on its outstanding secured convertible notes and resulting enforcement by noteholders of remedies on collateral which includes substantially all of Applied DNAs assets, its history of net losses, limited financial resources, limited market acceptance, the fact that there has never been a commercial drug product utilizing PCR-produced DNA technology approved for therapeutic use, the uncertainties inherent in research and development, future clinical data and analysis, including whether any of Applied DNAs or its partners product candidates will advance further in the preclinical research or clinical trial process, including receiving clearance from the U.S. Food and Drug Administration or equivalent foreign regulatory agencies to conduct clinical trials and whether and when, if at all, they will receive final approval from the U.S. FDA or equivalent foreign regulatory agencies, the unknown outcome of any applications to U.S. FDA or equivalent foreign regulatory agencies, Applied DNAs ability to obtain and maintain adequate protection for intellectual property rights relating to its product candidates and technologies, and various other factors detailed from time to time in Applied DNAs SEC reports and filings, including our Annual Report on Form 10-K filed on December 12, 2019 and our subsequent quarterly report on Form 10-Q filed on February 6, 2020, and other reports we file with the SEC, which are available at http://www.sec.gov. Applied DNA undertakes no obligation to update publicly any forward-looking statements to reflect new information, events or circumstances after the date hereof or to reflect the occurrence of unanticipated events, unless otherwise required by law.

View source version on businesswire.com: https://www.businesswire.com/news/home/20200326005345/en/

Contacts

investor contact: Sanjay M. Hurry, LHA Investor Relations, 212-838-3777, shurry@lhai.com program contact: Brian Viscount, Applied DNA, 631-240-8877, brian.viscount@adnas.com web: http://www.adnas.com, http://www.adnas.com/linearx twitter: @APDN

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Applied DNA Ships LinearDNA to Another Development Customer - Yahoo Finance