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Category Archives: DNA

This kitty DNA kit is the purrfect gift for cat parents and its on sale – KPRC Click2Houston

Posted: March 31, 2021 at 6:35 am

Does your kitty have the meow of a Bengal but the length of a Maine Coon? Stop guessing what might be behind these traits when you send in his Basepaws Breed + Health DNA Test. Get some more insight into his background with 13% off this kit plus a coupon PAWS15 for $15 off, bringing your total to just $114.

Adopt dont shop has become a way of life for many pet-loving families, but it often means they have limited information on their new cat. The Basepaws Breed + Health DNA Test can identify 21 different breeds among the four main breed divisions.

Most importantly, a comprehensive genetic report arrives with the breed results. This scans for 39 markers that can signal 17 different feline diseases. With these results, both owners and vets can strategize the best ways to give cats a long and healthy life.

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Its not hard to get this information. A single cotton swab in your cats cheek collects the necessary DNA sample. Mail this to the Basepaws lab and in just four to six weeks, your report arrives.

With 4.6 out of 5 stars on Amazon, cat owners are having great results and getting to know their best furry friends better. Whether you want to know just for fun or youre looking for clues to keep your cat healthier, more information never hurts.

Included in that information is something extra fun: how much like a tiger is your tiger-striped tomcat? Scaled on the Wild Cat Index, each tested cat gets a genomic report comparing them to wild cats like tigers, lions, cheetahs, and more.

DNA test kits have only become more affordable in recent years, but you can get this usually $149 kit for $114 with some deep discounts. Combine a 13% off sale with $15 off thanks to coupon code PAWS15 at checkout and snatch up this feline DNA kit.

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Largest-Ever DNA Mapping of the Philippines Shows 5 Major Immigration Waves Over 50 Millennia – SciTechDaily

Posted: at 6:35 am

Over 50 millennia, at least five major immigration waves have successively populated the Philippines, the most comprehensive survey of genetic variations in the country to date shows. This Uppsala University study, published in the scientific journal PNAS, comprises 2.3 million DNA markers from some 1,000 individuals.

Our findings suggest that instead of farming, climate change may have played a more important role in driving the mass movement of populations in various directions, says Maximilian Larena, researcher at Uppsala Universitys Department of Organismal Biology and first author of the study.

The Philippines more than 7,000 islands have always been a link between Southeast Asia, Australia, New Zealand, and the Polynesian islands of the Pacific Ocean. For millennia, the archipelago has served as a corridor for migration from one continent to another.

In a new study, a group of researchers from Australia, Taiwan, the Philippines, and elsewhere, led by Uppsala University, reveal the huge scale and complexity of the Filipino populations origins, kinship patterns, and genetic diversity. By typing 2.3 million DNA markers that are variable in us humans, and then using computational methods, the scientists have investigated the Filipinos DNA. In doing so, they analyzed these markers from more than 1,000 individuals, representing 115 Filipino cultural groups.

The study shows that over the millennia, at least five major waves of immigration built up the population of the Philippines. Different ethnic groups arrived successively. Negritos, the first Filipinos, were followed by various groups, including those who call themselves the Manobo and Sama.

The last three population waves occurred between 15,000 and 7,000 years ago a period in which climate change caused geographical transformations of the region. Sea levels rose, for example. Sunda, until then a large, fertile land mass between Southeast Asia and Oceania, was inundated and the land bridge between Taiwan and southern China was submerged beneath the waters.

Our study debunks a view that has dominated research on human history: that language, ways of life, culture, and people move together as a single unit a Neolithic package, as its often called. Were able to show that new groups of people migrated to the Philippines more than seven millennia ago, and it was these groups that took the Austronesian languages with them. It wasnt until three thousand years later that agriculture was taken there, probably by related groups. So that happened a long time afterwards, says Professor Mattias Jakobsson, senior author of the study.

Reference: Multiple migrations to the Philippines during the last 50,000 years by Maximilian Larena, Federico Sanchez-Quinto, Per Sjdin, James McKenna, Carlo Ebeo, Rebecca Reyes, Ophelia Casel, Jin-Yuan Huang, Kim Pullupul Hagada, Dennis Guilay, Jennelyn Reyes, Fatima Pir Allian, Virgilio Mori, Lahaina Sue Azarcon, Alma Manera, Celito Terando, Lucio Jamero Jr, Gauden Sireg, Renefe Manginsay-Tremedal, Maria Shiela Labos, Richard Dian Vilar, Acram Latiph, Rodelio Linsahay Saway, Erwin Marte, Pablito Magbanua, Amor Morales, Ismael Java, Rudy Reveche, Becky Barrios, Erlinda Burton, Jesus Christopher Salon, Ma. Junaliah Tuazon Kels, Adrian Albano, Rose Beatrix Cruz-Angeles, Edison Molanida, Lena Granehll, Mrio Vicente, Hanna Edlund, Jun-Hun Loo, Jean Trejaut, Simon Y. W. Ho, Lawrence Reid, Helena Malmstrm, Carina Schlebusch, Kurt Lambeck, Phillip Endicott and Mattias Jakobsson, 22 March 2021, Proceedings of the National Academy of Sciences.DOI: 10.1073/pnas.2026132118

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Largest-Ever DNA Mapping of the Philippines Shows 5 Major Immigration Waves Over 50 Millennia - SciTechDaily

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DNA Offers New Insights Into the The Origins and Decline of the Scythians – Technology Networks

Posted: at 6:35 am

Generally thought of as fierce horse-warriors, the Scythians were a multitude of Iron Age cultures who ruled the Eurasian steppe, playing a major role in Eurasian history. A new study published inScience Advancesanalyzes genome-wide data for 111 ancient individuals spanning the Central Asian Steppe from the first millennia BCE and CE. The results reveal new insights into the genetic events associated with the origins, development and decline of the steppes legendary Scythians.Because of their interactions and conflicts with the major contemporaneous civilizations of Eurasia, the Scythians enjoy a legendary status in historiography and popular culture. The Scythians had major influences on the cultures of their powerful neighbors, spreading new technologies such as saddles and other improvements for horse riding. The ancient Greek, Roman, Persian and Chinese empires all left a multitude of sources describing, from their perspectives, the customs and practices of the feared horse warriors that came from the interior lands of Eurasia.

Still, despite evidence from external sources, little is known about Scythian history. Without a written language or direct sources, the language or languages they spoke, where they came from and the extent to which the various cultures spread across such a huge area were in fact related to one another, remain unclear.

Although many of the open questions on the history of the Scythians cannot be solved by ancient DNA alone, this study demonstrates how much the populations of Eurasia have changed and intermixed through time. Future studies should continue to explore the dynamics of these trans-Eurasian connections by covering different periods and geographic regions, revealing the history of connections between west, central and east Eurasia in the remote past and their genetic legacy in present day Eurasian populations.

Reference: Gnecchi-Ruscone GA, Khussainova E, Kahbatkyzy N, et al. Ancient genomic time transect from the Central Asian Steppe unravels the history of the Scythians. Sci Adv. 2021;7(13):eabe4414. doi:10.1126/sciadv.abe4414.

This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source.

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Uncover Your Dog’s Breed And Health Markers With This DNA Test Kit, Now $60 – IFLScience

Posted: at 6:35 am

Youre not imagining it. Since the pandemic, there are more people out walking dogs than ever before. True, walking is one of the few activities that we are encouraged to do during these crazy times, so its inevitable that were seeing the likes of Fido and Rover more often, but statistics show that there has been a substantial increase in pet ownership since the start of the pandemic. In the United States, it's estimated that over 11 million households have welcomed a new fur baby, be that cat or dog, into their family.

With more and more of us working at home, we are spending A LOT of time with our pets, teaching them new tricks, trying out new looks and sharing our dinner with them. Plus we are getting to know their habits intimately and some of them were not too crazy about. Before you go all bad dog! on your canine, it might be best to find the underlying reasons for their behavior, and that could lie in their DNA.

Ever since dogs have been domesticated, many of them have been bred for specific reasons, and resulting behaviors have been passed on through the generations. Herding dogs, for example, may nip to get their flock in line, making sure they know whos the boss. Hunters tend to bark a lot, letting everyone know they found the desired prey (even if it's just your old lost sock) and their master better come quick. Some breeds require a lot of exercise, while others have separation anxiety.

Knowing a bit more about what your dogs ancestors were bred for can give you special insight into what makes your pup tick. And while just knowing the breed doesnt make the annoying habits simpler to cope with, it may give you an insight on the why, and help you to form and execute a training program.

Your dogs breed may be obvious, particularly if it has come from a certified breeder, but if you have given your heart to a Heinz 57 then who knows what breeds lie within? If thats the case, having the dogs DNA tested will not only give you a breakdown of its breed, or mixes thereof, but will also help to uncover any genetic health concerns and risk for certain diseases.

For just $59.99, a 24% savings off the regular price, DNA My Dog will help you do just that. Simply swab the inside of your pups cheek (hey, at least its not up the nose!) and then mail in the DNA sample. In two weeks not only will you get a full report including the above information, but from that you can start to understand your dog better, equip yourself with the knowledge to manage your dog, and strengthen your relationship.

Prices subject to change.

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Uncover Your Dog's Breed And Health Markers With This DNA Test Kit, Now $60 - IFLScience

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DNA ‘open to discussions’ with independent parties – Bahamas Tribune

Posted: at 6:35 am

DEMOCRATIC National Alliance Leader Arinthia Komolafe. Photos: Racardo Thomas

By EARYEL BOWLEG

Tribune Staff Reporter

ebowleg@tribunemedia.net

DEMOCRATIC National Alliance leader Arinthia Komolafe revealed yesterday that her party is open to having discussions with independent parties and viable independent candidates who share the same ideology and philosophy as the DNA.

Her comments came after the Coalition of Independents, headed by Lincoln Bain, issued a release calling for third parties to put aside differences and unite for the sake of our nation.

When asked if the DNA will unify with those independents to form a coalition, Mrs Komolafe expressed the partys willingness to work with others.

She said at a press conference: Well Im on the record speaking on behalf of the leadership of the DNA that we are open to having discussions with independent parties and viable independent candidates who share the same ideology and philosophy that we do, so that we can have a strong force in the next general election.

And so the DNA has committed to putting forward a full slate of candidates, whether that is a full slate of DNA standard bearers or that is a coalition of persons who are prepared to work with the DNA.

Mr Bain previously called for unity among third parties and expressed his willingness to even step down as leader of the independent group in order to achieve this as well.

With that in mind, I call for third parties to put aside differences and unite for the sake of our nation to come to the table and hold hands to lead us into new Bahamas, he said in a press release issued last week. The reservation for many third parties has always been who will lead and what will we name it. To this end I hereby express my willingness to step down as a leader in order to save our nation. This would allow the people to choose who should lead the unified body.

It is time for all leaders to put personal ambitions aside to humble ourselves and put (the) country first. We further call for the members of these organisations to speak to your leaders and encourage them to come to the table and join forces in an effort to defeat the FNM and PLP and restore our nation.

The DNA recently announced the ratification of 19 candidates for the next general election.

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DNA Plc: Decisions of DNA Plc’s Annual General Meeting and organisation of Board of Directors – GlobeNewswire

Posted: at 6:35 am

DNA PLC STOCK EXCHANGE RELEASE* 26 MARCH 2021, 10:30 am EET

DNA Plc's Annual General Meeting was held in Helsinki on 26 March 2021.

The Annual General Meeting (AGM) adopted the consolidated financial statements and parent company financial statements for the financial year 1 January 31 December 2020. It was noted that the Board of Directors had proposed to the Annual General Meeting that the company pays no dividend for the financial year 2020 and that the net profit for 2020 is allocated to retained earnings. The AGM decided to approve the proposal concerning the use of distributable funds shown on the balance sheet. The AGM also decided to discharge the Members of the Board of Directors and the CEO from liability for the financial year 1 January 31 December 2020.

It was decided that the number of the Members of the Board of Directors will be six. The AGM decided to elect Sigve Brekke as the Chair of the Board of Directors and the following people as Members of the Board of Directors: Birgitte Engebretsen, Gaute Simen Gravir, Nils Katla, Hvard Naustdal and Trine Rnningen. The members of the board are independent of the company but non-independent of Telenor Group. The Board Members who are not independent of Telenor Group shall not be paid remuneration.

On 17 March 2021, DNA announced that the company's CEO Jukka Leinonen moves to head Telenor Groups Nordic Cluster fulltime in the autumn 2021. When the new CEO of DNA takes office, Jukka Leinonen will take the position as DNAs Chair of the Board of Directors.

The AGM decided to elect Authorised Public Accountants Ernst & Young as the companys auditor. APA Terhi Mkinen will act as the principal auditor.

More information:DNA Corporate Communications, tel. +358 44 044 8000, communications@dna.fiDNA's Board of Directors:https://corporate.dna.fi/company/board-of-directors

*Due to delisting of DNAs share from Nasdaq Helsinki on 3 February 2020, DNA is not subject to reporting obligations as an issuer of shares as set out in the Finnish Securities Markets Act. DNA is still subject to reporting obligations as an issuer of senior unsecured fixed rate notes due in 2025 (ISIN: FI4000312095) listed in Nasdaq Helsinki stock exchange.

DNA is one of the leading telecommunications companies in Finland. We want to make our customers' daily lives less complicated. We offer connections, services and devices for homes and workplaces, contributing to the digitalisation of society. DNA's customers are continuously among the world mobile data usage leaders. DNA has about 3.6 million subscriptions in its fixed and mobile communications networks. The company has been awarded numerous times as an excellent employer and family-friendly workplace. In 2020, our total revenue was EUR 934 million and we employ about 1,600 people around Finland. DNA is a part of Telenor Group, a leading telecommunications company across the Nordics. More information: http://www.dna.fi, Twitter @DNA_fi, Facebook @DNA.fi and LinkedIn @DNA-Oyj.

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DNA needed to identify semi driver killed in fiery crash on I-65 – Journal & Courier

Posted: at 6:35 am

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MONTICELLO, Ind. The semi-tanker driver killed Tuesday in the fiery crash on Interstate 65 still has not been positively identified,White County Coroner Tony Deivel said Friday.

The man was badly burned in the crash, and Deivel is using DNA to positively identify the driver, the coroner said.

Thursday's autopsywas inconclusive about the man's cause of death, and toxicology is pending, Deivel said.

The driver who died inthe crash was northbound on I-65 at 11 a.m. Tuesday when he lost control of his semi in southern White County a few miles north of Tippecanoe County.

More: One killed in fiery crash on I-65 in White County

About a mile south of the Indiana 18 exit, the semi sideswipeda northbound van drivenby James Harrington, 66, of Thomasville, North Carolina, police said. Harrington was not injured.

The wayward semi entered the median, plowed through the cable barrier and hit dual-semi trailers in the southbound lanes, splitting the front trailer in two and knocking the back trailer into the ditch, according to Indiana State Police.

Frank Duran Jr., 56, of Chicago, was driving the southbound rig struck by the northbound semi, which was hauling the tanker full of food-grade material. Duran wasnot injured, Indiana State Police said.

The wayward semi came to rest on the right side of the southbound lanes, where fire surrounded the rig.

The crash closed southbound I-65 at Indiana 18 for many hours Tuesdaywhile police investigated the crash and the wreckage was removed.

Emergency crews work the scene of a three vehicle crash that killed one motorist, Tuesday, March 23, 2021 in Brookston.(Photo: Nikos Frazier / Journal & Courier)

Reach Ron Wilkins at 765-420-5231 or at rwilkins@jconline.com. Follow on Twitter: @RonWilkins2.

Read or Share this story: https://www.jconline.com/story/news/2021/03/26/dna-needed-identify-semi-driver-killed-fiery-crash-65/6980788002/

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DNA vs. RNA 5 Key Differences and Comparison …

Posted: March 3, 2021 at 2:01 am

ListicleDec 18, 2020| by Ruairi J Mackenzie, Editor for Technology Networks

Deoxyribonucleic acid (DNA) and Ribonucleic acid (RNA) are perhaps the most important molecules in cell biology, responsible for the storage and reading of genetic information that underpins all life. They are both linear polymers, consisting of sugars, phosphates and bases, but there are some key differences which separate the two1. These distinctions enable the two molecules to work together and fulfil their essential roles. Here, we look at 5 key differences between DNA and RNA. Before we delve into the differences, we take a look at these two nucleic acids side-by-side.

A Comparison of the Helix and Base Structure of RNA and DNA

Comparison

DNA

RNA

Both DNA and RNA are built with a sugar backbone, but whereas the sugar in DNA is called deoxyribose (left in image), the sugar in RNA is called simply ribose (right in image). The deoxy prefix denotes that, whilst RNA has two hydroxyl (-OH) groups attached to its carbon backbone, DNA has only one, and has a lone hydrogen atom attached instead. RNAs extra hydroxyl group proves useful in the process of converting genetic code into mRNAs that can be made into proteins, whilst the deoxyribose sugar gives DNA more stability4.

The Chemical Structures of Deoxyribose (left) and Ribose (right) Sugars

The nitrogen bases in DNA are the basic units of genetic code, and their correct ordering and pairing is essential to biological function. The four bases that make up this code are adenine (A), thymine (T), guanine (G) and cytosine (C). Bases pair off together in a double helix structure, these pairs being A and T, and C and G. RNA doesnt contain thymine bases, replacing them with uracil bases (U), which pair to adenine1.

Eukaryotic cells, including all animal and plant cells, house the great majority of their DNA in the nucleus, where it exists in a tightly compressed form, called a chromosome5. This squeezed format means the DNA can be easily stored and transferred. In addition to nuclear DNA, some DNA is present in energy-producing mitochondria, small organelles found free-floating in the cytoplasm, the area of the cell outside the nucleus.

The three types of RNA are found in different locations. mRNA is made in the nucleus, with each mRNA fragment copied from its relative piece of DNA, before leaving the nucleus and entering the cytoplasm. The fragments are then shuttled around the cell as needed, moved along by the cells internal transport system, the cytoskeleton. tRNA, like mRNA, is a free-roaming molecule that moves around the cytoplasm. If it receives the correct signal from the ribosome, it will then hunt down amino acid subunits in the cytoplasm and bring them to the ribosome to be built into proteins5. rRNA, as previously mentioned, is found as part of ribosomes. Ribosomes are formed in an area of the nucleus called the nucleolus, before being exported to the cytoplasm, where some ribosomes float freely. Other cytoplasmic ribosomes are bound to the endoplasmic reticulum, a membranous structure that helps process proteins and export them from the cell6.

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DNA Script Joins GE Research Collaboration to Develop On-Demand Vaccines and Therapeutics in Response to Biothreats for DARPA NOW Project – PRNewswire

Posted: at 2:01 am

SOUTH SAN FRANCISCO, Calif. and PARIS, March 2, 2021 /PRNewswire/ -- DNA Script, a leading pioneer in enabling DNA synthesis on demand, today announced that the company has been selected by GE Research to join a collaboration to develop a rapid response, mobile medical manufacturing platform to enable on-demand production of nucleic acid-based vaccines and therapies. The $41-million, five-year project was awarded as part of the Defense Advanced Research Projects Agency's (DARPA) Nucleic Acids On-Demand World-Wide (NOW) program. As part of the agreement, DNA Script will receive up to $9.35 million.

The collaboration, which seeks to create a platform that can produce thousands of ready-to-use vaccine doses at sites of need in under three days, will employ DNA Script's enzymatic DNA synthesis (EDS) platform to quickly generate high-fidelity nucleic acids to fuel GE's industrial-scale nucleic acid amplification production capability. Building nucleic acids by traditional chemical synthesis requires the handling and ventilation of hazardous chemicals and environmental conditions not amenable to rapid response mobile manufacturing. DNA Script's SYNTAX EDS system prints high-quality nucleic acids in a compact benchtop instrument without the need for toxic solvents or special conditions.

DARPA's NOW program, managed by Dr. Amy Jenkins in the Biological Technologies Office, was created to develop a rapid, mobile, medical manufacturing platform. The resulting DNA- and/or RNA-based vaccines and therapeutics would be used to better prepare deployed forces against biothreat attacks and emerging infectious disease as well as used for humanitarian operations. Developing a platform such as this would enable the deployment of vaccines and therapeutics like those developed to fight the COVID-19 pandemic in just days rather than weeks or months.

"Having the ability to produce small batches of ready-to-use vaccines in a few days could prove transformative to beat back a pandemic and avoid the emergence of more dangerous variants," said Thomas Ybert, Chief Executive Officer of DNA Script. "We are excited to collaborate with GE to employ the speed, efficiency and ease-of-use of our EDS technology to create a manufacturing platform that will enable much faster production and deployment of vaccines and ensure a much faster response to potential biothreats."

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As part of the early deployment of its technology and SYNTAX system, DNA Script also recently announced a partnership with the French Department of Defense to develop a rapid mobile manufacturing platform to enable the fast detection of emerging biothreats.

About DNA ScriptFounded in 2014 in Paris, DNA Script is a disruptive DNA synthesis company engineering biology to accelerate breakthroughs in life science. The company is pioneering an alternative to traditional DNA synthesis called enzymatic DNA synthesis, or EDS, making this technology accessible to labs with the world's first benchtop enzymatic synthesis instrument, SYNTAXTM System. By putting DNA synthesis back in the lab, DNA Script is transforming life science research through innovative technology that gives researchers complete control and unprecedented autonomy. http://www.dnascript.com

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Maryland neighbors and best friends discover they’re actually sisters through DNA test – FOX 5 DC

Posted: at 2:01 am

Suddenly Family podcast explores shocking family discoveries through DNA

The podcast series Suddenly Family is exploring what happens when DNA tests reveal family secrets, such as best friends finding out they're actually sisters.

Two Maryland neighbors and best friends never understood why they felt so close to one another, closer than they did to their own families. Turns out, they were sisters.

Ana Zellers made the discovery through a DNA test where it was revealed that she and her childhood neighbor and best friend Joanne Smart shared the same father.

"I put all the pieces together," Zellers says, recounting the moment she broke the news to Smart. "I said, 'You realize that my son is the only living grandson of our biological father. And my son is your nephew...and my grandchildren are related to you."

The discovery is detailed on a new podcast from CNN called "Suddenly Family," hosted by journalist Samuel Burke.

"Eleven percent of people who take a DNA test will discover that one of their parents isn't their biological parent," Burke told FOX 5.

READ MORE:Marylands largest Powerball jackpot remains unclaimed but winners waiting to cash in is nothing new

He says the podcast episode about the Maryland women, titled "Girl Next Door," is one of the most moving of the series.

"She feels more at home with [the Smarts] than she does her own family," Burke says. "Well, it turned out that her mother had an affair with the neighbor's husband."

Other episodes of the podcast include stories about a gay man who finds out he has a child and even a personal anecdote from Burke himself about how he found out he wasn't related to his very own family.

Download the FOX 5 DC News App for Local Breaking News and Weather

To listen to the "Suddenly Family" podcast, click here.

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Maryland neighbors and best friends discover they're actually sisters through DNA test - FOX 5 DC

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