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The Evolutionary Perspective
Category Archives: DNA
New DNA research points way to faster flu vaccines
Posted: November 26, 2012 at 6:44 pm
An experimental vaccine based on a molecule related to DNA protects animals against influenza and may one day offer an ultra-rapid way to develop new shots for humans, German scientists reported on Sunday.
Assuming it also works in people, the new approach could allow commercial flu vaccines to be designed and manufactured in weeks rather than months.
Making vaccines quickly is critical in fighting flu, particularly during a pandemic when health authorities and drugmakers are in a race to keep up with mutating strains of virus.
Flu vaccines have traditionally been produced in chicken eggs, a tricky and lengthy process. More recently some firms have started using animal cell cultures, with Novartis on November 20 winning the first U.S. approval for such a product.
Both approaches, however, still involve virus cultivation, which can result in variable yields and production delays.
The new vaccine developed by Lothar Stitz of Friedrich-Loeffler-Institut and colleagues uses a quicker approach. It is made solely of messenger RNA (mRNA) - a single-stranded molecule that carries information telling cells which proteins to make.
"The only thing we need is the sequence of the relevant genes," Stitz said. "It's a new option and it doesn't take long to do."
His team vaccinated mice, ferrets and pigs with an mRNA vaccine and found that the immune response was similar or better than that found with conventional vaccines. What is more, the new vaccines showed high efficacy in very young and very old animals, which can be a problem with current flu shots.
Reporting their results in the journal Nature Biotechnology, the scientists calculated that a completed vaccine could be produced within six to eight weeks of the genetic code of a flu virus strain being published.
In contrast growing vaccines in fertilised chicken eggs can take up to six months, while using cell cultures may reduce that by up to eight to 10 weeks.
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New DNA research points way to faster flu vaccines
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DNA not always the magic bullet in crime investigations
Posted: at 6:43 pm
When someones DNA triggers a match through a statewide database linking that person to the scene of a crime, it doesnt necessarily mean the case is a slam dunk for police and prosecutors.
Next comes the hard part: Investigators must prove there isnt an otherwise noncriminal explanation for why that persons genetic material was found on someones body, on a murder weapon or inside another persons home.
A lot of people think that if you get a DNA hit that, Bingo, you got the person, but it doesnt work that way, Oneida County District Attorney Scott McNamara said. What law enforcement needs to be cognizant of is that there are many innocent explanations for things to be where they are, and as we get better and better at being able to find DNA, we also have to keep in mind that there is an innocent way for DNA to be left behind.
Since New Yorks statewide database of DNA collected from convicted criminals has been expanded over the years, the ever-growing pool of samples to compare against has helped local police agencies crack tough cases, officials said.
For instance, DNA from a strand of hair found on Jennifer Bennetts body in 2007 ultimately linked Craig Ingersoll to her strangulation. Although Ingersoll never had been a suspect, a DNA match led investigators to question Ingersoll after Utica police arrested him in 2010 for stealing from a business and state law required him to provide a sample of his DNA.
This is great technology, but its not easy, Whitestown police Chief Donald Wolanin said. Knocking on doors and interviewing people is still one of our best tools and probably most reliable. Were arresting more people by doing basic police interviews than we are with DNA technology.
Here are a few examples of how complicated some cases can be, even with DNA evidence.
A bloody cloth
Utica police continue to investigate the killing of someone who was stabbed repeatedly. A bloody cloth recovered from the homicide scene did lead to a DNA match with a known person, but that individual has denied any involvement in the killing, prosecutors said.
DNA gives us a lead, but it doesnt give us enough to proceed, McNamara said. When we confronted the person with the bloody cloth, he said he didnt know what we were talking about. So, just because we find a bloody cloth with his DNA on it, that doesnt mean he killed anyone.
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DNA not always the magic bullet in crime investigations
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Teach your Droid DNA some GSM tricks
Posted: at 6:43 pm
Harness the Droid DNA's prowess to rock not just roaming on AT&T or T-Mobile.
The Droid DNA is one slick device, but will it work on T-Mobile or AT&T, too?
One of the new HTC Droid DNA's unsung features is its ability to jump onto global GSM networks, which is great when traveling overseas. Verizon certainly thinks so, and thanks to an unlocked SIM card slot, you can also slip in an AT&T or T-Mobile card and flip the DNA over to operate on those carriers.
Now I first heard of the Droid DNA's freedom to link to American GSM networks from smartphone news site Android Central, and since I had just finished reviewing the DNA, my ears perked up right away. The question is, would you really want to port a gadget like the Droid DNA over to a carrier it wasn't designed for? For me the answer is: yes, absolutely.
That's because this hot piece of mobile hardware is extremely lust-worthy in its own right, no matter what network it grabs signal from. First of all, it's one of a handful of U.S. smartphones to boast quad-core processing. The DNA also runs powerful Android 4.1 Jelly Bean software, plus features a massive and sharp 5-inch (1080p) screen.
Unfortunately as part of Verizon's Droid brand, the Droid DNA is exclusive to Big Red, which is a big pain for people who subscribe to other U.S. carriers. For that alone I had to see for myself whether the DNA's radio could be coaxed to grab hold of a local GSM signal correctly. In addition, though I'm technically a T-Mobile customer, I'm constantly taking multiple phones (from various cell providers) for test-drives simultaneously, which doesn't always work out smoothly. Sorry Google Voice, you're a great solution but sometimes you fail miserably and I would love to receive texts and calls reliably for a change.
Pop that LTE card The first step was to power down my HTC Droid DNA test unit and pop open its LTE/SIM card slot. Located on the top edge, I just stuck a push pin (though a small paper clip could work) into the pin hole next to the slot. This ejected a tiny metal tray and the Verizon LTE SIM held within. Trust me, I know 4G LTE cards don't grow trees, so I stashed it in a safe place.
The LTE/SIM card slot is on the top edge.
Insert your GSM SIM Since the Verizon LTE card is the same size as a micro-SIM, I had no trouble placing my T-Mobile SIM in the Droid DNA's SIM tray. Once inserted I powered up the DNA and waited for the signal indicator to detect a signal.
Add an APN When I saw a few bars of coverage appear in the top right of the Droid DNA's screen, I knew I was in business. Next I had to tell the phone what to do with its newfound GSM network. Within the Android settings menu, I tapped Mobile Data, then selected GSM/UMTS Options. From here I hit Access Point names and saw just one entry, VZWINTERNET -- the APN for Verizon's network.
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Teach your Droid DNA some GSM tricks
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Little Mix DNA – Video
Posted: November 24, 2012 at 7:43 pm
Little Mix DNA
x factors winners 2011From:Hannah GlynnViews:0 0ratingsTime:04:03More inMusic
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Little Mix DNA - Video
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MarCum 2012/2013 – Video
Posted: at 7:43 pm
MarCum 2012/2013
PROFESSIONAL SONAR MarCum offers both digital and flasher sonar systems. Each system is embued with over a decade of cutting edge sonar engineering. The MarCum digital sonar systems blend the sonar DNA from MarCum LX Flashers with new digital fish finding technology. And the MarCum flasher-sonar systems remain the most powerful and advanced flasher-sonar systems ever built. UNDERWATER CAMERAS Teamed with the industry #39;s finest camera optics, MarCum underwater viewing systems play rich, vivid color images on spacious LCD viewscreens. Maxed-out resolution, definition and sunlight viewability make these systems the undisputed new category leader. Plus a complete array of on-screen adjustments and display data put valuable fish-pattern intel right at your fingertips. Learn more at http://www.MarCumtech.comFrom:MarcumTubeViews:0 0ratingsTime:00:30More inSports
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MarCum 2012/2013 - Video
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Orthorexia.TV : DNA Fashion
Posted: at 7:43 pm
Orthorexia.TV : DNA Fashion the formula for universe expansion/contraction!
http://www.theamberinstitute.comFrom:MinisterEnQi SangRealViews:1 0ratingsTime:11:26More inSports
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Orthorexia.TV : DNA Fashion
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#20: LG Nexus 4 [Compare to iPhone 5 / HTC One X / Galaxy Nexus] – Video
Posted: at 7:43 pm
#20: LG Nexus 4 [Compare to iPhone 5 / HTC One X / Galaxy Nexus]
Its that time of the year again when Google contracts a manufacturer to manifest the head hancho smartphone for all Android purist. The Nexus 4. The Neighborhood Tech Man opens up the device, runs a quadrant benchmark, talks a little sh*t and compares the LG Nexus 4 to the following devices: Apple iPhone 5, HTC One X and the Samsung Galaxy Nexus (Verizon/CDMA). Tweet or Email the HTM any questions you have the HTM will answer your question during his Q/A video. Follow Me On Twitter twitter.com/TheHoodTechMan instagam.com/TheHoodTechMan GMAIL - TheHoodTechMan @ Gmail.com -------------------------------------------- tags: apple sprint verizon t mobile tmobile t-mobile 4s mbps processor phonearena att at t i pad phone smartphone ces 2013 retina 1080p phablet htc dna unbox unboxing pure google tim cook steve jobs 4.2 4.1.2 iv iiii 4 lcd 3 screen google+ siiiFrom:TheHoodTechManViews:22 0ratingsTime:08:51More inScience Technology
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#20: LG Nexus 4 [Compare to iPhone 5 / HTC One X / Galaxy Nexus] - Video
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2013 KTM 1190 Adventure – Video
Posted: at 7:43 pm
2013 KTM 1190 Adventure
KTM 1190 ADVENTURE Pure passion drives everyone at KTM each and every day. Pure bikes are the result. We have been working and developing non-stop, prototypes have circled the Earth thirty times -- and now the time has come: With the new Adventure generation, KTM sets new standards in the travel segment! More than a decade ago, the first Adventure from Mattighofen was launched -- with DNA from the same KTM that won the Rallye Dakar eleven times in a row. The uncompromising transfer of knowledge from racing to mass production ensured that the KTM Adventures have always stayed ahead of the rest of the world. With plenty of new highlights, the latest KTM 1190 Adventure generation now defines new benchmarks to leave the competition behind on the asphalt. An impartial comparison proves that the two new KTM Adventure models are the lightest and most powerful bikes in their class. The foundations are their ultralight, extremely strong chrome molybdenum steel trellis frame and their 1195 cc, 150 hp V2 engine. High-end suspension components by WP Suspension, peerless brakes by global market leader Brembo and assistance systems developed in close co-operation with Bosch round of the package, giving the new KTM 1190 Adventure a clear lead in dynamics and safety from the start. Its weight of only 230 kilograms -- ready to race with fuel, that goes without saying -- will help it maintain that lead. The 1190 Adventure need not fear any competition on the road. And were it not for the ...From:SupercarHallViews:18 1ratingsTime:01:46More inAutos Vehicles
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2013 KTM 1190 Adventure - Video
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Christmas Remix ft. Little Mix – DNA – Video
Posted: at 7:43 pm
Christmas Remix ft. Little Mix - DNA
If you think i #39;m weird please stop watching.... Im having a laugh so i dont careFrom:aaamsxViews:1 0ratingsTime:01:12More inComedy
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Christmas Remix ft. Little Mix - DNA - Video
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ASSASSINS CREED 2 GAMEPLAY DNA 3 PART1 – Video
Posted: at 7:43 pm
ASSASSINS CREED 2 GAMEPLAY DNA 3 PART1
I created this video with the YouTube Video Editor (www.youtube.comFrom:G4MERM4NIACOViews:0 0ratingsTime:14:32More inGaming
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