Category Archives: DNA

Ancient Egyptians were vexed by it, using sulfur to dry it out. Shakespeare wrote of its "bubukles, and whelks, and knobs, and flames o' fire."

Today, acne plagues us still. Doctors can cure some cancers and transplant vital organs like hearts, but they still have trouble getting rid of the pimples and splotches that plague 85% of us at some time in our lives usually, when we're teenagers and particularly sensitive about the way we look.

But new research hints that there's hope for zapping zits in the future, thanks to advances in genetic research.

Using state-of-the-art DNA sequencing techniques to evaluate the bacteria lurking in the pores of 101 study volunteers' noses, scientists discovered a particular strain of Propionibacterium acnes bacteria that may be able to defend against other versions of P. acnes that pack a bigger breakout-causing punch.

As best as dermatologists can tell, zits occur when bacteria that reside in human skin, including P. acnes, feed on oils in the pores and prompt an immune response that results in red, sometimes pus-filled bumps. But the study subjects who had the newly discovered bacterial strain weren't suffering from whiteheads or blackheads, according to a report published Thursday in the Journal of Investigative Dermatology.

Someday, the realization that "not all P. acnes are created equal" might help dermatologists devise treatments that more precisely target bad strains while allowing beneficial ones to thrive, said Dr. Noah Craft, a dermatologist at the Los Angeles Biomedical Research Institute who conducted the study with colleagues from UCLA and Washington University in St. Louis.

Doctors might prescribe probiotic creams that deliver "good" P. acnes to the face the same way a daily serving of yogurt helps restore healthy bacteria in the digestive tract.

"There are healthy strains that we need on our skin," Craft said. "The idea that you'd use a nuclear bomb to kill everything what we're currently doing with antibiotics and other treatments just doesn't make sense."

The research is part of a broad effort backed by the National Institutes of Health to characterize the so-called human microbiome: the trillions of microbes that live in and on our bodies and evolve along with us, sometimes causing illness and often promoting good health.

Most of the microbiome attention so far has gone to studying species in the gut, said study leader Huiying Li, an assistant professor of molecular and medical pharmacology at UCLA's Geffen School of Medicine. But the NIH's Human Microbiome Project, which funds her research, also looks at microbial communities in the nasal passages, the mouth, the urogenital tract and the skin.

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DNA science points to better treatment for acne

Future - DNA Slowed Down - DJ DoeMan
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Future - DNA Slowed Down - DJ DoeMan - Video

Court takes up question of arrestee DNA sampling
Court takes up question of arrestee DNA sampling http://www.wtxl.com "Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, comment, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational or personal use tips the balance in favor of fair use." 107.Limitations on exclusive rights: Fair use Notwithstanding the provisions of sections 106 and 106A, the fair use of a copyrighted work, including such use by reproduction in copies or phonorecords or by any other means specified by that section, for purposes such as criticism, comment, news reporting, teaching (including multiple copies for classroom use), scholarship, or research, is not an infringement of copyright. In determining whether the use made of a work in any particular case is a fair use the factors to be considered shall include mdash; (1) the purpose and character of the use, including whether such use is of a commercial nature or is for nonprofit educational purposes; (2) the nature of the copyrighted work; (3) the amount and substantiality of the portion used in relation to the copyrighted work as a whole; and (4) the effect of the use upon the potential market for or value of the copyrighted work. FAIR USE NOTICE: These pages/video may contain copyrighted ( ) material the use of which has not always been specifically authorized by the ...

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Court takes up question of arrestee DNA sampling - Video

Haplogroup J2 (Y-DNA) - MrIgnorantKiller Y-DNA
Haplogroup J2 (Y-DNA)

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Haplogroup J2 (Y-DNA) - MrIgnorantKiller Y-DNA - Video

Alien DNA? Zecharia Sitchin on Sumerian History
Zecharia Sitchin (RIP) talks on some points of his research findings in this short clip. Some claim his work is mixed with dis-info. I think people should explore and express that what is within them. Ideas then presented, without prejudice- so the individual, can make of it on their own accord, what resonates- or otherwise, to what it`s meaning is. ..once again, enjoy the revealing

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Alien DNA? Zecharia Sitchin on Sumerian History - Video

Mert YONAR Ercan SARIKAYA - DNA (Original Mix)
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DNA Replication Slideshow!
For Mrs.Torres, AP Biology, 02/27/13. By Kim Peck, Blanca Arriaza, and Remington Ho Prepare to have your mind blown by the sheer amount of information you are about to receive.

By: Blanca Arriaza

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DNA Replication Slideshow! - Video

WOBURN, Mass., Feb. 26, 2013 /PRNewswire/ --Covaris, Inc. introduced the single-tube FFPE DNA Extraction Kit at the 2013 Advances in Genome Biology and Technology (AGBT) meeting held recently in Marco Island, Florida. This newest innovation from Covaris provides an optimized reagent and protocol for high-yield DNA extraction from Formalin-Fixed, Paraffin Embedded (FFPE) tissue samples. Adaptive Focused Acoustic (AFA) Technology is used to emulsify and separate the paraffin, while simultaneously re-hydrating the tissue sample in an aqueous solution within a few minutes. Covaris Focused-ultrasonicators enable the purely mechanical processing of the samples, eliminating the need for organic solvents. Large Molecular Weight DNA is efficiently extracted from FFPE samples, with greater yield when compared to organic extraction with other commercially available kits. The AFA-based kit brings standardization to a previously uncontrolled pre-analytical preparatory step.

The FFPE Nucleic Acid Extraction Kit utilizes AFA Technology, the standard method for DNA fragmentation for Next Generation Sequencing (NGS). An optional DNA fragmentation step can be included in the workflow to precisely size the DNA for applications requiring short DNA fragments, such as NGS all in the same tube. This optional integrated single-tube DNA Shearing streamlines the sample preparation workflow, while also doubling total DNA yield when compared to extraction without fragmentation.

FFPE is a widely used method for archiving tissue specimens; especially clinical samples. Extraction of DNA or RNA from FFPE tissue has traditionally been a challenge as it requires removing the paraffin, rehydrating the sample, and reversing the formaldehyde cross-links, which results in low yields and poor quality of nucleic acid samples. Additionally, the traditional extraction processes require the use of hazardous or difficult-to-handle solvents. Archived FFPE tissues are a rich resource for studying gene variations or gene expression profile changes. This trend has been growing with the continued advances in the fields of genomics and trancriptomics. These new applications benefit from the high-quality starting material and improved workflow provided by the Covaris FFPE DNA Extraction Kit.

About Covaris Covaris, Inc. (www.covarisinc.com) provides advanced sample preparation systems for life and analytical science. Covaris sample prep technologies support a wide variety of applications including Next-Generation Sequencing, ChIP, proteomics, formulations, and compound management. Our patented Adaptive Focused Acoustic (AFA) technology is the industry standard for DNA shearing, and is used by major genome centers, academic, and clinical institutions worldwide. AFA brings unsurpassed speed and efficiency to biological and chemical sample preparation. The AFA process, which is based on shock wave physics, delivers controlled, precise, and accurate acoustic energy to biological and chemical samples.

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Covaris introduces a novel FFPE DNA extraction kit at AGBT 2013

LA JOLLA, Calif. and CORALVILLE, Iowa, Feb. 27, 2013 /PRNewswire/ --SGI-DNA, a wholly owned subsidiary of Synthetic Genomics Inc. (SGI), and Integrated DNA Technologies, Inc. (IDT), the world leader in custom oligonucleotide synthesis, today announced an expanded collaboration to develop, manufacture, and market a broad range of synthetic DNA products. Financial details of the agreement were not disclosed.

SGI also announced the official launch of SGI-DNA, which is responsible for all aspects of the development, manufacture, and commercialization of SGI's synthetic DNA technology business. Fernanda Gandara has assumed the role of General Manager for SGI-DNA, and will remain as SGI's Senior Vice President for Business Development.

In February of 2012, IDT and SGI began to co-manufacture and commercialize small synthetic gene products up to 5 kb. IDT also launched its gBlocks Gene Fragments product line, for use in combination with SGI's proprietary DNA technologies, including Gibson Assembly. These IDT and SGI technologies have already revolutionized synthetic biology applications by substantially lowering DNA synthesis costs and by making DNA assembly more efficient and reliable.

IDT and SGI-DNA are now expanding this collaboration to manufacture and co-brand cloned synthetic DNA constructs up to 2 Mbp, a product offering that has never been available until today. This will enable new applications including metabolic and whole genome engineering through de novo DNA synthesis. SGI-DNA is manufacturing the synthetic DNA products and making them available through IDT, and is now IDT's exclusive supplier of the larger DNA constructs. The two companies will also work together on IDT's launch of an expanded gBlocks Gene Fragment offering, expected later in 2013.

"Over the last year, we have grown our in-house gene synthesis business, and effectively worked together with IDT to co-manufacture and commercialize smaller synthetic gene products," said J. Craig Venter, Ph.D., SGI's Founder and Chief Executive Officer. "We are excited about what we will accomplish through the expanded relationship with IDT, which combines SGI-DNA's unique expertise with large, complex gene products and IDT's experience in manufacturing and delivering small DNA products to customers around the globe."

Joseph Walder, Ph.D., IDT's Founder and Chief Executive Officer, agreed. "Through this strengthened collaboration, SGI-DNA and IDT will enable the research community by providing a complete solution, from short genes to very large synthetic constructs, at prices and with delivery times simply unavailable in the market today. Enabling new and better research has always been the essence of IDT's mission, so it's the perfect fit."

For more information about how to order IDT/SGI-DNA products please visit, https://www.idtdna.com/pages/products/genes/custom-gene-synthesis.

About SGI-DNA SGI-DNA, a wholly owned subsidiary of Synthetic Genomics, Inc. (SGI) founded in 2013 and headquartered in La Jolla, CA, provides differentiated synthetic DNA solutions to leading organizations with demands for large and/or complex DNA constructs. Building on the scientific breakthroughs from leading scientists J. Craig Venter, Hamilton Smith, Clyde Hutchison, Dan Gibson and their teams, SGI-DNA utilizes unique and proprietary DNA synthesis technologies from SGI to produce synthetic genes, genetic pathways, and whole genomes quickly and cost-effectively. SGI-DNA is responsible for all commercial aspects of SGI's synthetic DNA business and focuses on strategic business relationships with both academic and commercial researchers. For more information, visit http://www.sgidna.com.

About IDT Integrated DNA Technologies, Inc. (IDT) is the largest supplier of custom synthetic nucleic acids in the world, serving the areas of academic research, biotechnology, clinical diagnostics, and pharmaceutical development. IDT's primary business is the manufacture of custom primers, probes, and genes for research and diagnostic applications. Today, IDT synthesizes and ships an average of 36,000 custom oligos per day to more than 86,000 customers worldwide. IDT's manufacturing locations include facilities in Coralville, Iowa; San Diego, Calif.; Leuven, Belgium; and Singapore. For more information, visit http://www.idtdna.com.

About Synthetic Genomics Inc. SGI, a privately held company founded in 2005, is dedicated to developing and commercializing genomic-driven solutions to address a wide range of global challenges. The company is focused on several key research and business programs including: developing new synthetic DNA products and technologies through SGI-DNA, algae biofuels, new and improved food and nutritional products, and clean water technology. SGI is also involved in synthetically derived vaccine development through Synthetic Genomic Vaccines Inc. (SGVI), a business unit co-founded with the J. Craig Venter Institute; and in developing sustainable crops such as castor and sweet sorghum and agricultural products through AgraCast, a company co-founded with Plenus S.A. de C.V. For more information go to: http://www.syntheticgenomics.com.

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SGI-DNA, a New Subsidiary of Synthetic Genomics Inc., and IDT Announce Broader Collaboration to Develop, Manufacture ...

SCOTUS DNA: Attorney challenges DNA swabbing practices before the US Supreme Court
WASHINGTON. -- The US Supreme Court hears arguments on a Maryland case involving the police and their right to take DNA samples following an arrest.

By: CNS Maryland

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