Category Archives: DNA

Source Resonance and Incoming DNA Upgrades
Intel on X flares, Gateways and how YOU can assist in acceleration prior to May 24. Articles and the Ascension eCourse at http://www.sandrawalter.com Blessin...

By: Ascension Integration

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Source Resonance and Incoming DNA Upgrades - Video

Programa do Ratinho - 17/05/2013 - Exame de DNA
Programa do Ratinho - 17/05/2013 - Exame de DNA.

By: novocanaloficial2013

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Programa do Ratinho - 17/05/2013 - Exame de DNA - Video

Atmosphere - Wanessa @DNA TOUR live in BELO HORIOZONTE/MG

By: Edmundo Nunes

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Atmosphere - Wanessa @DNA TOUR live in BELO HORIOZONTE/MG - Video

DNA IC
just some crap IC I made in like an hour LOL I ended up not adding anything else to it cause this song was just difficult. only upload for le vicky to see XD...

By: HydroDiffusion

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DNA IC - Video

Entrepreneurial DNA: Joe Abraham at TEDxBend
Joe is the founder/CEO of bosiDNA.com, featured in the Wall Street Journal for its breakthrough technology and award-winning accelerator. Entrepreneurship ha...

By: TEDxTalks

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Entrepreneurial DNA: Joe Abraham at TEDxBend - Video

BMS302 Oral Presentation- Genetic Screening DNA Sequencing

By: RIPkas1

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BMS302 Oral Presentation- Genetic Screening

DNA - Little Mix (Guitar)
Me playing DNA by Little Mix on guitar 🙂

By: Adriiaana G

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DNA - Little Mix (Guitar) - Video

"DNA" Minecraft Oasis Ep 46
Now they finally have some privacy! Submit YOUR Fan Art to the Cupquake Facebook Fan page and see it on the next episode!! Make sure to LIKE and COMMENT!!! /...

By: iHasCupquake

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"DNA" Minecraft Oasis Ep 46 - Video

OSHKOSH Joseph Freys conviction for a rape more than 20 years ago was overturned Wednesday by a Winnebago County Circuit Court judge based on DNA testing and other evidence that showed Frey, who was serving a 102-year sentence, was likely the wrong man.

In a subdued hearing, Judge Daniel Bissett agreed that Freys conviction must be vacated in the interest of justice.

However, the journey to freedom for Frey has not ended. He will remain in the Winnebago County Jail until prosecutors decide whether to retry him. Bissett ordered him held in lieu of $100,000 cash bail.

Frey, now 53, was charged with breaking into a UW-Oshkosh students apartment in 1991 and sexually assaulting her at knifepoint. He was convicted on Feb. 2, 1994, by a Winnebago County jury despite his claims of innocence, the victims dubious identification of him as the attacker, the lack of a DNA match and destruction by an Oshkosh Police detective of important evidence before the trial.

DNA found at the crime scene as a result of new testing requested by the Wisconsin Innocence Project matched a man who, after the 1991 attack, went on to sexually assault two sisters, ages 12 and 13, in Fond du Lac. He has since died.

Assistant District Attorney Adam Levin said the new evidence, including the DNA test and witness interviews, isnt significantly different from the old evidence, saying it was similar to what was used to convict Frey in 1994. That old evidence included a jailhouse informant, the victims identification of Frey in a live in-person lineup, prior sexual assault charges and DNA results from the victims bedsheet that excluded Frey as the source.

The jury knew that the DNA on the sheet did not match the defendant, Levin said.

But Levin said the new testing, which shows that DNA from convicted sex offender James E. Crawford was commingled with the victims DNA on her bedsheet, is a significant new fact that the jury did not know.

UW-Madison law student Micheal Hahn with the Innocence Project told Bissett there is no innocent explanation for the discovery of Crawfords DNA at the crime scene. He also pointed to a Winnebago County Sheriffs investigation requested by Levin last month that revealed Crawford may have been trying to confess to the attack in this case prior to his death in 2008.

Whether Frey is retried for the 1991 rape will hinge on the results of DNA testing of condoms collected from Frey as part of a Brown County case, Levin said.

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Man's rape conviction overturned after DNA testing

May 22, 2013 Adventitious changes in cellular DNA can endanger the whole organism, as they may lead to life-threatening illnesses like cancer. Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich now report how byproducts of respiration cause mispairing of subunits in the double helix.

The DNA in our cells controls the form and function of every cell type in our bodies. The instructions for this are encoded in the linear sequence of the four subunits found in DNA, the bases adenine (A), cytosine (C), guanine (G) and thymine (T). Random changes in the sequence can lead to cell dysfunction, and may result in unrestricted cell proliferation and malignancies. Mutations can be induced by a variety of agents. For example, cellular respiration, i.e. the reduction of inspired oxygen to water, which powers cell function, also generates highly reactive oxygen species that can damage DNA, with the purine bases G and A being particularly susceptible to this kind of attack.

"Reactive oxygen species are responsible for two different sorts of DNA damage, as they induce formation of both 8-oxo-G and FaPy-G," says Professor Thomas Carell of the Department of Chemistry at LMU. In 2004, work done by Carell and his team defined how 8-oxo-G generates mutations. However, the basis for the mutagenic effect of FaPy-G has remained obscure -- until now. In their latest publication, Carell and his colleagues describe how FaPY-G leads to mispairing of bases in the double helix.

Pernicious partner swapping One G in one strand of the double helix normally matches up with a C on the other, forming a G:C pair. But as a consequence of damage by reactive oxygen species, the guanine base may be transformed into FaPy-G, so that we get a FaPy-G:C base pair. "We have now shown that, in the course of DNA replication prior to cell division, FaPy-G interacts with adenine, leading to the formation of FaPy-G:A base pairs. This partner swap is unusual, since unmodified guanine normally does not team up with adenine," Carell notes.

FaPy-G is subsequently recognized as abnormal and is removed by DNA repair enzymes. The missing base is replaced by a T -- which is the usual partner for A. The net result is that the original G:C base pair has been converted into an A:T pair, and the base sequence has undergone a potentially dangerous mutation.

This outcome is made possible by the fact that the cell's damage-control systems find it surprisingly difficult to distinguish the normal guanine base from its aberrant derivative FaPy-G during DNA replication. "That this defect then leads to mispairing with adenine is one of the main reasons for the spontaneous development of tumors," says Carell. "So with every breath we take, our risk of getting cancer goes up by a teeny-weeny bit." Further insights into the reasons why FaPy-G often eludes the cell's detection and correction systems could help to improve the treatment of cancer, as the inhibition of DNA repair processes in tumor cells increases their sensitivity to chemotherapeutic drugs.

The study was supported by DFG grants awarded to Collaborative Research Centers 646 and 749 and the Center for Integrated Protein Science Munich (CIPSM), an Excellence Cluster.

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DNA damage: The dark side of respiration