Category Archives: DNA

Maury DNA: I Hope You #39;re NOT the Father! - I Charge Him to See "His" Kid! - DNA Opposite Day 2006!
Another request filled thanks to the Maury upload form! https://docs.google.com/forms/d/1EgRSL-N4gg2b1AxAn9vU11ZlMJfq44qH74xcfpW1qiA/viewform Description fro...

By: therazorsedge28

See the original post here:
Maury DNA: I Hope You're NOT the Father! - I Charge Him to See "His" Kid! - DNA Opposite Day 2006! - Video

The National Institutes of Health is launching an initiative to determine whether sequencing an infant's DNA can improve on the well-established "heel stick" blood test to screen newborns for potentially life-threatening diseases.

The five-year, $25 million project reflects the declining costs of mapping an individual's genetic code and anticipates the day when, if enthusiasts' predictions are borne out, a baby's DNA could be routinely sequenced and stored in a medical record.

But the value of the technology in newborn screening isn't certain, and experts are eager to examine a host of ethical and other questions about the use of genetic information to improve infant care.

Currently, nearly all 4 million infants born in the U.S. each year are tested for up to 31 life-threatening or debilitating conditions through heel-stick programs, in which a drop of blood is taken via a pin-prick in the heel. The programs, administered in each state, detect potentially treatable problems in about 12,500 cases, enabling interventions that can save lives or prevent millions of dollars in lifetime health-care costs, said Alan Guttmacher, director of the National Institute of Child Health and Human Development, which along with the National Human Genome Research Institute is funding the initiative.

One of the big successes of such screening, Dr. Guttmacher said, is for a condition called phenylketonuria, or PKU, an enzyme disorder that leads to the buildup of an amino acid. If the condition is detected before symptoms arise, changes in diet can prevent it, but once symptoms emerge, the disease, marked by serious neurological problems, is irreversible.

But the 31 conditions make up a fraction of as many as 8,000 inheritable disorders that can affect children. States vary in the maladies they test.The hope is that the new effort can "shed light on other disorders and see how genomic data might inform care for newborns generally," Dr. Guttmacher said.

Under the program, the DNA of some 2,000 newborns will be sequenced at five institutions: Brigham and Women's Hospital and Boston Children's Hospital in Boston, which are working jointly; Children's Mercy Hospital in Kansas City, Mo.; University of California, San Francisco; and University of North Carolina at Chapel Hill.

Click for more from The Wall Street Journal.

Here is the original post:
Researchers study value of DNA analysis in screening newborns

Jay Menes as the DNA Doctor for "Walang Hanggan" May 2, 2012
Scene with Dawn Zulueta and Nonie Buencamino.

By: Jay Menes

Read the rest here:
Jay Menes as the DNA Doctor for "Walang Hanggan" May 2, 2012 - Video

Ken Murray/NEW YORK DAILY NEWS

Vito Spano, a retired deputy inspector with the NYPD Cold Case Squad, says the Robert Fleming rape-murder case gave direction to advances in DNA technology.

When Selena Cooper and her 9-year-old daughter were murdered in 1988, it was probably the second or third year the NYPD was utilizing DNA.

But it wasnt understood. It was super Star Trek stuff.

RELATED: ROBERT FLEMING SENTENCED IN 1988 SODOMY, MURDER OF GIRL, 9

We didnt know how you could get it or how you could extract it. At the time, DNA was something that you needed a significant quantity of and if it was degraded in any way, shape or form it wouldnt work.

To top it all off, we didnt have a statewide database so every suspect we had needed to be cotton swabbed and DNA typed a process that took months since we had to use one of the labs in Penn State University.

RELATED: DNA HELPS POLICE CATCH SUSPECT IN 1988 MURDERS

Back then no one really knew where the technology behind DNA was going. If I was to tell people back in the late 80s how far it advanced, they would never believe me.

But this case would make believers. Within the next 15 years, New York finally got a state DNA database. Thats how we finally identified Robert Fleming as a suspect.

Read more from the original source:
Detective: DNA evidence was in its infancy in Fleming case

Public release date: 4-Sep-2013 [ | E-mail | Share ]

Contact: Timothy S. Paul tp2111@columbia.edu 212-305-2676 Columbia University's Mailman School of Public Health

Even before they are born, babies accumulate changes in their DNA through a process called DNA methylation that may interfere with gene expression, and in turn, their health as they grow up. But until now it's been unclear just how long these changes during the prenatal period persist. In a new study, researchers at the Columbia Center for Children's Environmental Health at the Mailman School of Public Health establish that signs of DNA methylation persist through early childhood, suggesting the factors that influence these changes during or before pregnancy could have effects throughout a child's life.

The study, published in an online edition of PLOS ONE, is the first to look at DNA methylation changes over time in children.

"The current dogma is that DNA methylation marks are set during early development and are mainly persistent thereafter. However, there were no data in humans to either support or refute this hypothesis. We set out to fill this data gap," explains lead author Julie Herbstman, PhD, assistant professor of Environmental Health Sciences at the Mailman School.

Recent evidence points to environmental exposures like arsenic, lead, and air pollution as factors in epigenetic changesthe umbrella term for DNA methylation and other alterations to gene expression that don't come from DNA mutations. While the health impact of small changes in DNA methylation is not yet clear, there is concern that alterations caused by environmental exposures during important periods of development that could have effects across a lifetime. Generally, low levels of global DNA methylation have been linked to genomic instability, which can lead to DNA damage. (Global DNA methylation is defined as methylation levels measured in aggregate for all genetic material, not specific to one or more genes.)

Center researchers analyzed global DNA methylation levels in blood at two different time points. Cord blood was analyzed from 279 children who are part of the Center's Mothers & Newborns study in Northern Manhattan and the South Bronx. Of these children, 165 also had blood collected at age 3.

The authors found that cord blood methylation was correlated with and significantly predicted the level of methylation at 3 years old. This supports the hypothesis that DNA methylation changes occurring early in life may have lasting impacts.

Maternal BMI Affects Levels of DNA Methylation

The researchers examined one specific factor to see how it affected DNA methylation in childrenthe mother's body mass index prior to becoming pregnant. Children born to moms with high BMIs had low levels of global DNA methylation, an association that was seen again at age 3.

Read the original post:
DNA changes during pregnancy persist into childhood

How to Recover Deleted SMS Text Messages from HTC DNA
Can I retrieve safely the deleted or lost SMS Text messages from my HTC Droid DNA phone? [Dr.Fone for Android (Windows)] http://www.phone-data-recovery.org/a...

By: Selena Lee

Go here to read the rest:
How to Recover Deleted SMS Text Messages from HTC DNA - Video

How to Recover Deleted Music from HTC DNA
Lost your music files on HTC Droid DNA? Here is the best way for you to get them back: [Dr.Fone for Android (Windows)] http://www.phone-data-recovery.org/and...

By: Selena Lee

Read more:
How to Recover Deleted Music from HTC DNA - Video

How to Recover Deleted Photos from HTC DNA
Free download the powerful HTC Droid DNA Data Recovery - Dr.Fone for Android: [Dr.Fone for Android (Windows)] http://www.phone-data-recovery.org/android-data...

By: Selena Lee

See the rest here:
How to Recover Deleted Photos from HTC DNA - Video

How to Recover Deleted Files from HTC DNA
Here is the best way to retrieve your deleted or lost files from HTC Droid DNA for you: [Dr.Fone for Android (Windows)] http://www.phone-data-recovery.org/an...

By: Selena Lee

More here:
How to Recover Deleted Files from HTC DNA - Video

Darkness, Deception, DNA
Lisa Bradford had two beautiful children and a charming, doting husband, Dennis. She thought she had a happily ever after ahead of her. However, when Dennis ...

By: idfullepisodes

See the original post:
Darkness, Deception, DNA - Video