Category Archives: DNA

Tuesday, April 22, 2014

IT&E records corroborate testimony about Crisostomo using Kintaro cell phone

A Federal Bureau of Investigation forensic examiner in the nuclear DNA unit at the FBI Lab in Quantico, Virginia, testified yesterday that Joseph A. Crisostomos DNA matched the DNA obtained from swab samples taken from the vagina of murdered bartender Emerita R. Romero.

Testifying for the CNMI government in the ongoing jury trial of 40-year-old Crisostomo in Superior Court, FBI forensic examiner Susannah Kehl disclosed that she tested the sexual assault kit that the FBI Saipan Office sent to their laboratory and that she concluded the positive presence of semen in Romeros vagina.

James Calderwood, IT&E manager for network services, also took the witness stand yesterday about records of cell phone calls from the numbers of Romero and Alicia Kintaro.

Kintaro testified last week that Crisostomo borrowed her cell phone in the early morning of Feb. 5, 2012. IT&E records revealed that when Kintaros cell phone was used, the originating cell tower for the call was at Palms Resort in San Roque.

Palms Resort is located across the former La Fiesta Mall where Romeros body was found by FBI agents on Feb. 7, 2012.

In her testimony, FBI forensic examiner Kehl first explained about DNA and how to extract, test, and compare it.

Kehl said that in Romeros case, the FBI Saipan Office made two submissions to the FBI Labone from FBI special agent Joe Auther and then from FBI special agent Haejun Park.

Kehl said she did not detect blood on a metal door taken from La Fiesta Mall.

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Crisostomo DNA matched Romero samples

PUBLIC RELEASE DATE:

21-Apr-2014

Contact: Anita Srikameswaran srikamav@upmc.edu 412-578-9193 University of Pittsburgh Schools of the Health Sciences

PITTSBURGH, April 21, 2014 Malfunctions in the molecular "proofreading" machinery, which repairs structural errors in DNA caused by ultraviolet (UV) light damage, help explain why people who have the disease xeroderma pigmentosum (XP) are at an extremely high risk for developing skin cancer, according to researchers at the University of Pittsburgh School of Medicine and the University of Pittsburgh Cancer Institute (UPCI). Their findings will be published this week in the early online version of the Proceedings of the National Academy of Sciences.

Previous research has shown that a DNA-repair protein called human UV-damaged DNA-binding protein, or UV-DDB, signals for a repair when two UV-DDB molecules bind to the site of the problem, said senior investigator Bennett Van Houten, Ph.D., the Richard M. Cyert Professor of Molecular Oncology, Pitt School of Medicine, and co-leader of UPCI's Molecular and Cell Biology Program.

"Our new study shows UV-DDB makes stops along the DNA strand and transiently attaches to it, causing a proofreading change in the protein's conformation, or shape. If the DNA is damaged the protein stays, if the DNA is not damaged the protein leaves," Dr. Van Houten said. "When it comes to a spot that has been damaged by UV radiation, two molecules of UV-DDB converge and stay tightly bound to the site, essentially flagging it for the attention of repair machinery."

The researchers followed the trail of single molecules of UV-DDB by tagging them with light-emitting quantum dots, enabling them to watch the molecules jump from place to place in real time on both normal and UV-exposed DNA strands.

They also tracked a mutant UV-DDB protein associated with XP, an inherited, incurable disease of light sensitivity that affects about 1 in 250,000 people. They found that the mutant UV-DDB molecules are still capable of binding to DNA, but continued to slide along the DNA rather than staying put to signal where the fix was needed.

"Without this important damage control, UV-induced errors could accumulate to cause cell alterations that foster cancer development," Dr. Van Houten said. "Like a bus with no brakes, the XP-associated UV-DDB complex stays on the road and sees possible passengers, but keeps going past the stop."

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Malfunction in molecular 'proofreader' prevents repair of UV-induced DNA damage

Mass DNA Testing Used To Find Rape Suspect At French School
Authorities have begun testing DNA from 527 male students and staff at the Fenelon-Notre Dame Catholic school to find an accused rapist. Follow Matt Moreno: ...

By: NewsyWorld

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Mass DNA Testing Used To Find Rape Suspect At French School - Video

DNA a extins urmarirea penala pe numele lui Radu Mazare

By: B1TVChannel

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DNA a extins urmarirea penala pe numele lui Radu Mazare - Video

STRUCTURE OF DNA
Structure of DNA: The DNA molecule is a polymer consisting of several thousand pairs of nucleotide monomers.Each nucleotide consists of three components. The...

By: 7activestudio

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STRUCTURE OF DNA - Video

DNA da Balada | Index Candy Pool Party - Lorena Simpson 13/04/14
No ltimo domingo, 13/04, foi dia de mais uma edio mgica da Index Pool Party, que estava mais doce que nunca! A festa, realizada no Vale do Sol, nessa edi...

By: DNA da Balada

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DNA da Balada | Index Candy Pool Party - Lorena Simpson 13/04/14 - Video

Slipped DNA
For more information, log on to- http://shomusbiology.weebly.com/ This DNA video explains the structure and functions of slipped DNA and the role of having s...

By: Suman Bhattacharjee

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Slipped DNA - Video

"Money DNA" Melanie Benson Strick Intimate Conversations LIVE @AllanaPratt
http://www.IntimateConversationsLIVE.com OMG how much do I love Melanie Benson Strick??? She #39;s so wise, vulnerable, conscious, human, empowering... and what ...

By: Allana Pratt

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"Money DNA" Melanie Benson Strick Intimate Conversations LIVE @AllanaPratt - Video

Forced DNA Harvesting/Cheek Swabs @ LA Vehicle Checkpoints

By: Micheal Norton

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Forced DNA Harvesting/Cheek Swabs @ LA Vehicle Checkpoints - Video

The Universe, Source, Dimensions, DNA, Meditation is Key, The Self
Just meditate and stay in tune with your true self and not the egoistic self, that would be problematic.

By: Jay Jota

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The Universe, Source, Dimensions, DNA, Meditation is Key, The Self - Video