Category Archives: DNA

DNA, Chromosomes and Genes
This video explains the relationship between DNA, chromosomes and genes. To best understand this video you should make sure you have watched my #39;What is DNA? #39; video. Chromosomes are made of...

By: Jeremy LeCornu

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DNA, Chromosomes and Genes - Video

DNA - Seu Desejo seu Comando
Sim, verdade! Voc sente que est mudando, assim como Nicolas! Faa como ele! Adquira os 14 udios em http://www.seudesejoeseucomando.com.br.

By: Seu desejo Seu Comando

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DNA - Seu Desejo seu Comando - Video

D N A - DiaLovers
I don #39;t ANIME or MUSIC. Just for entertainment of fans only. For Diabolik Lovers.

By: Noble Princess

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D N A - DiaLovers - Video

DNA TESTING PART 1: 20140914
The Knowing Thyself Project: Cynthia #39;s DNA Testing Part 1.

By: Cynthia Leandre

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DNA TESTING PART 1: 20140914 - Video

MILAN ITALY TGX DNA THE DAY WE STARTED
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By: Kirby Dela Cruz

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MILAN ITALY TGX DNA THE DAY WE STARTED - Video

MILAN ITALY TGX DNA THE DAY WE STARTED P5
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By: Kirby Dela Cruz

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MILAN ITALY TGX DNA THE DAY WE STARTED P5 - Video

Dna Gheorghita si fetele fac atmosfera in casa /p1

By: Tony

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Dna Gheorghita si fetele fac atmosfera in casa /p1 - Video

DNA repair mechanism - Base excision repair
This dna repair lecture explain the base excision repair process and its importance. For more information, log on to- http://shomusbiology.weebly.com/ Download the study materials here- http://shom...

By: Suman Bhattacharjee

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DNA repair mechanism - Base excision repair - Video

Quick facts:

There's a new effort to find cold-case killers and rapists, including whoever was responsible for the rapes and murders of Michella Welch and Jennifer Bastian back in 1986.

Twelve-year-old Michella and 13-year old Jennifer both were riding their bicycle alone near Tacoma parks when they were abducted and murdered. Michella, whose body was found in Puget Park, was killed in March of 1986. Jennifer, who was found in Point Defiance Park, was murdered that August. Both girls were sexually assaulted, and police believe the same man is responsible for both murders.

But even though investigators distributed a composite sketch of a man on a bicycle seen following Jennifer the day she disappeared, no suspect has ever been identified.

Pierce County native Lindsey Wade was 11-years-old when the girls were murdered. Wade is now a detective with the Tacoma Police Department working cold cases, including the two murders she's never forgotten.

It was really the first time I can recall hearing about something in the news that was particularly terrifying to me, Wade said of the two cases.

While looking into the 1999 disappearance of 2-year old Teekah Lewis, Wade learned that the DNA of 36 residents of the Special Commitment Center at McNeil Island the facility that houses our states civilly committed sexually violent predators -- had never been collected and processed because they committed their crimes before state law made DNA collection from sex offenders mandatory in 1990.

Wade told KIRO 7s Amy Clancy she was surprised to learn that the DNA of those long-imprisoned serial rapists and sex offenders was not in any database that would allow her -- or other detectives -- to solve other cold-case crimes.

I was shocked, I was really surprised, Wade said. These are pretty much our states worst of the worst, in my opinion, when it comes to sexually violent predators.

So with money from a federal grant, Wade was able to collect all the SCC residents' DNA, have it tested, and entered into the crime-fighting database called CODIS.

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DNA of sex offenders being tested in cold cases

PUBLIC RELEASE DATE:

15-Sep-2014

Contact: Shawna Williams shawna@jhmi.edu 410-955-8236 Johns Hopkins Medicine @HopkinsMedNews

Researchers at Johns Hopkins have identified a highly sensitive means of analyzing very tiny amounts of DNA. The discovery, they say, could increase the ability of forensic scientists to match genetic material in some criminal investigations. It could also prevent the need for a painful, invasive test given to transplant patients at risk of rejecting their donor organs and replace it with a blood test that reveals traces of donor DNA.

In a report in the September issue of The Journal of Molecular Diagnostics, the research team says laboratory tests already show that the new analytical method compares favorably with a widely used DNA comparison technique. The researchers have applied for a patent.

The current method for comparing DNA to determine paternity and advance criminal investigations counts the number of repeats in certain highly repetitive blocks of DNA that are not part of genes. But, says James Eshleman, M.D., Ph.D., a professor of pathology at the Johns Hopkins University School of Medicine, "Repeat testing will only detect DNA that makes up at least 1 percent of a DNA sample, so it's not great for situations in which results depend on small amounts of material within a larger sample."

Making comparisons based on common "point mutations," or variations within actual genes, was long considered impractical because of the high costs of DNA sequence testing. But the cost of sequencing has fallen so low in recent years that Eshleman's team revisited the idea.

Choosing a block of DNA with 17 common point mutations in close proximity along the genome, Marija Debeljak, a technician in Eshleman's laboratory, looked for mismatches in various mixtures of lab-grown human cells. "We could detect cells when they made up just .01 percent of the mixture, which is a big improvement over the current method, which can only detect DNA that makes up 1 to 5 percent of a sample," Eshleman says.

In addition to forensic and paternity testing applications, the new method could also potentially be used to monitor the health of bone marrow transplant patients, Eshleman says. Testing transplant patients' blood for low levels of leukemia blood cells could theoretically be used as an early warning system, but current analysis based on the standard repeat testing is not sensitive enough to detect low levels of recurring leukemia DNA in blood.

In contrast, when the researchers tested bone marrow recipients' blood with their new system, they found that it could detect patient DNA. "If we're able to develop this test for commercial use, it could also free some solid-organ transplant recipients of the invasive biopsies that are currently used if rejection is suspected," Eshleman says.

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Researchers develop improved means of detecting mismatched DNA