Category Archives: DNA

MEXICO CITY, Oct. 15 (UPI) -- DNA testing confirmed that human remains found in a mass grave in southern Mexico are not those of missing students who disappeared Sept. 26. after clashing with police.

Mexico's Attorney General Jesus Murillo Karam noted that DNA testing is still being conducted for remains discovered in four other grave sites. The graves were found based on a tip provided by alleged assassins with the Guerreros Unidos gang who confessed to working with police to attack the students.

Authorities have so far arrested 50 people, mostly local police, in connection with the Sept. 26 attack, which occurred as students from Normal Rural de Ayotzinapa attempted to leave Iguala in Guerrero state aboard three commercial buses they had earlier commandeered -- a common practice among students of the school and largely tolerated. Police blocked the buses and then opened fire. A number of students were taken away by the police and 43 were ultimately reported missing.

Family members of the 43 missing students and demonstrators have taken to the streets in Guerrero, Mexico City, Morelia, Oaxaca, San Cristobal de las Casa and Veracruz to protest organized crime and encourage the government's search for the missing.

Protests turned violent Monday when protesters set fire to government buildings in Guerrero state capital, Chilpancingo, to express outrage over the alleged police involvement in the students' disappearance.

It is unclear when the results of the DNA tests on the remains in the four other grave sites will be available.

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Newswise Stony Brook, NY, October 15, 2014 The proteins that drive DNA replicationthe force behind cellular growth and reproductionare some of the most complex machines on Earth. The multistep replication process involves hundreds of atomic-scale moving parts that rapidly interact and transform. Mapping that dense molecular machinery is one of the most promising and challenging frontiers in medicine and biology.

Now, a team of scientists from Stony Brook University, the U.S. Department of Energys Brookhaven National Laboratory (BNL), Cold Spring Harbor Laboratory, and the Imperial College in London have pinpointed crucial steps in the beginning of the replication process, including surprising structural details about the enzyme that unzips and splits the DNA double helix so the two halves can serve as templates for DNA duplication. Their findings are published today online in the journal Genes and Development.

The genesis of the DNA-unwinding machinery is wonderfully complex and surprising, said study coauthor Huilin Li, a Professor of Biochemistry and Cell Biology at Stony Brook University and a biologist at BNL. Seeing this helicase enzyme prepare to surround and unwind the DNA at the molecular level helps us understand the most fundamental process of life, and how the process might go wrong. Errors in copying DNA are found in certain cancers, and this work could one day help develop new treatment methods that stall or break dangerous runaway machinery.

The research combined electron microscopy, perfectly distilled proteins, and a method of chemical freezing to isolate specific moments at the start of replication. It picks up where two previous studies by Li and colleagues left off. They first determined the structure of the "Origin Recognition Complex" (ORC), a protein that identifies and attaches to specific DNA sites to initiate the entire replication process. The second study revealed how the ORC recruits, cracks open, and installs a crucial ring-shaped protein structure (Mcm2-7) that lies at the core of the helicase enzyme.

But DNA replication is a bi-directional process with two helicases moving in opposite directions. The key question, then, was how does a second helicase core get recruited and loaded onto the DNA in the opposite orientation of the first?

To our surprise, we found an intermediate structure with one ORC binding two rings, said Brookhaven Lab biologist and lead author Jingchuan Sun. This discovery suggests that a single ORC, rather than the commonly believed two-ORC system, loads both helicase rings.

One step further along, the researchers also determined the molecular architecture of the final double-ring structure left behind after the ORC leaves the system, offering a number of key biological insights.

We now have clues to how that double-ring structure stably lingers until the cell enters the DNA-synthesis phase much later on in replication, said study coauthor Christian Speck of Imperial College, London. This study revealed key regulatory principles that explain how the helicase activity is initially suppressed and then becomes reactivated to begin its work splitting the DNA.

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Scientists Map Key Moment in Assembly of DNA-Splitting Molecular Machine

DNA Were going to identify serial rapists, says panelist.

All of Utahs backlogged DNA evidence from sex-assault cases should by analyzed, and all such rape kits from present and future cases should be processed as well.

Thats what Ned Seale, a spokesman for a special work group, told the Law Enforcement and Criminal Justice Legislative Interim Committee on Wednesday.

The ad hoc work group has defined a priority system for analyzing about 2,700 backlogged rape kits statewide that contain DNA and other forensic evidence, said Jeff Carr, deputy commissioner for the Utah Department of Public Safety.

Earlier this year, the Utah Legislature allocated $750,000 for the analysis of backlogged forensic kits. Some federal funding also may be available for processing them, Carr said.

The state crime lab is establishing the "Utah Quick Analysis Program," Carr told the committee, to analyze DNA but not necessarily all the evidence in the kit. The protocol would be faster and less expensive than the present system. Rather than months, DNA could be analyzed in 60 to 90 days.

Law enforcement agencies in other states that have begun testing backlogged rape kits are discovering that one in three find matches in CODIS, the national criminal DNA database, Donna Kelly, Utah Prosecution Council, said in an interview

"Were going to identify serial rapists," Kelly explained.

Rep. Jennifer Selig, D-Salt Lake City, who has spearheaded the movement in Utah to get backlogged rape kits processed, said she is "cautiously optimistic" that law enforcement agencies will begin to process all such evidence to help give victims some satisfaction while seeking out offenders.

Whether legislation to fund the analysis of sexual-assault evidence will come out of the 2015 legislative session remains unclear. Also uncertain is whether the Legislature will require agencies to test all rape kits.

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Group urges Utah lawmakers to fund DNA analysis of all rape kits

Dr Brock Foru DNA part 1
Dr Brock discusses DNA test http://www.lovingourchildren.foru.com.

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Dr Brock DNA Part 3
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Dr Brock DNA Part 2
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Loka - D.N.A

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Abhishek Bachchan Flags Off DNA Womens Half Marathon
Abhishek Bachchan Flags Off DNA Womens Half Marathon. Visit - https://www.unitezz.com . India #39;s Biggest Bollywood Entertainment Website for More Exclusives Like us on Facebook - https://www.face ...

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Abhishek Bachchan Flags Off DNA Womens Half Marathon - Video

Andy Falco ~ Adam Gieckel ~ DNA
Festy5 Andy Falco Adam Gieckel, Adam #39;s song that they recorded for a various artists album called "Around The Town" Here #39;s the link http://www.cdbaby.com/cd/aroundthetownacollaborat.

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Andy Falco ~ Adam Gieckel ~ DNA - Video

Abhishek Bachchan Flags Off The DNA Women #39;s Half Marathon
Bollywood Actor Abhishek Bachchan Flags Off The DNA Women #39;s Half Marathon. Visit - https://www.unitezz.com . India #39;s Biggest Bollywood Entertainment Website for More Exclusives Like us on...

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Abhishek Bachchan Flags Off The DNA Women's Half Marathon - Video