Category Archives: DNA

HARTFORD DNA was recovered from two doorknobs at the East Hartford apartment complex that was the scene of a 2010 triple homicide that matched samples from Horvil "Trix" Lebrick, according to testimony Monday.

Dr. Angela Przech was one of five witnesses called by the state during the sixth day of Lebrick's murder trial. Lebrick is accused of fatally shooting Shawnalee Hudson, 26, during a botched robbery at a Woodcliff Estates apartment rented to Omari Barrett on May 6, 2010.

Przech testified that two doorknobs in the south stairwell of the apartment building were among the items from the scene swabbed and tested for DNA. The samples from the doors matched the sample of Lebrick's DNA that was submitted to the lab, according to Przech's testimony.

During cross-examination, defense attorney Christopher Duby questioned Przech about retesting that was done after the lab learned that there may have been problems with their testing kits. Przech said that all samples tested with the kits in question were retested and the tests done on the doorknobs yielded the same results.

The jury also heard from James Stephenson, who was working at the state forensics laboratory when the bullets and casings from the crime scene were examined. Stephenson, who is now retired and running his own consulting firm, testified that there were seven 9mm bullets and casings discovered in the apartment, along with four .38/.357-caliber bullets.

Six of the 9mm bullets likely came from the same weapon, but one had markings on it that indicated it came from a different firearm, he said. He testified that the same was true of the 9mm bullet casings; six were consistent with one weapon, one was different.

When asked about the examination of the marks on the bullets, Stephenson said it was like comparing "apples and oranges."

No actual firearms were presented as evidence in the case. One gun was found inside the apartment, according to previous testimony, but none of the bullets fired inside the apartment matched the weapon.

Barrett, who rented the apartment, previously testified that he rushed home that day after Hudson called him to say that three men had kicked in the apartment door.

He said he told Hudson to get his .357 Magnum revolver and then he drove from Hartford armed with a 9mm pistol. When he arrived, Barrett said he found the men inside his apartment and fired at one of them, setting off an exchange of gunfire that left Hudson and two of the intruders, twins Andrew and Andraw Moses, dead. Lebrick was the only person arrested.

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DNA, Firearm Evidence Heard During Day 6 of East Hartford Murder Trial

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The promise of molecular electronics gets hoisted up the flagpole periodically, but now an international team of researchers based out of the Hebrew University of Jerusalem claim to have made a breakthrough with DNA molecules that they believe may be the most significant development in the last decade of molecular electronics research.

In research published in the journal Nature Nanotechnology, a international group of researchers hailingfrom Cyprus,Denmark, Italy,Spain, and the United Stateshas demonstrated that electriccurrent can be transmitted through long DNA molecules. They believe that this demonstration could lead to the development of DNA-based electroniccircuits.

Much research has focused on making DNAcircuits. For instance, scientists have explored schemes in which DNA would serve as a kind of circuit board or scaffold for precisely assembling electroniccomponents at resolutions as small as 6 nanometers.But so far its all been without much success.

DNA was thought to be a promising basis for molecular circuits,because of its ability to self-assemble into various structures. Buta big stumbling block has been that no one has been able to measure reliably or quantitatively the flow of current through the molecule.

While other research has been able to produce transport measurements of current through DNA, the results have appeared contradictory at times because of differences in the measured molecules and experimental set-ups.

In this latest work, the researchers were able to measure reliably and reproducibly currents ranging from tens of picoamperes (pA) to more than 100pA over distances ranging from tens of nanometres to more than 100nm.

"This research paves the way for implementing DNA-based programmable circuits for molecular electronics, a new generation of computer circuits that can be more sophisticated, cheaper and simpler to make," said Danny Porath, a professor at the Hebrew University of Jerusalem, in a press release.

While this is no doubt an important development, there are still huge obstacles that remain for molecular electronics to ever be realized. Perhaps the biggest remaining issue is how to maintain the stability of molecules under typical integrated circuit processing conditionsin particular, the propensity of direct vapor deposition of metallic electrodes onto molecules to result in shorts.

We are likely to see this research have an impact on stability during manufacture and otherissues.

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DNA Can Carry Current, a Promising Step Toward Molecular Electronics