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Category Archives: DNA
My First DNA BOMB #1 – Video
Posted: November 25, 2014 at 3:47 pm
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Food intolerance test by DNA | Dermatological – Video
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Food intolerance test by DNA | Dermatological
The DNA genetic analysis AdisonLab Genetics, has the answer. The ADN Patent technology, through your saliva, helps you solving this genetic disorder identifying the foods that provokes...
By: Adisonlabgenetics
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Food intolerance test by DNA | Dermatological - Video
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My Story Life | Ep 2 | L’amour c’est compliqu. (Bombe DNA AW) – Video
Posted: at 3:47 pm
My Story Life | Ep 2 | L #39;amour c #39;est compliqu. (Bombe DNA AW)
YOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO tous le monde c #39;est ATXHD et aujourd #39;hui on se retrouve aprs un long moment d #39;absence qui vas tre justifier dans une prochaine vido.
By: ATXHD
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My Story Life | Ep 2 | L'amour c'est compliqu. (Bombe DNA AW) - Video
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How To Balance Youtube & College:COD AW Double DNA Bomb – Video
Posted: at 3:47 pm
How To Balance Youtube College:COD AW Double DNA Bomb
What #39;s good everybody hope everyone is having a good day.Todays video is about balancing youtube and college. My guest in this video is Mr.Leonard Tips Check him out here ...
By: Kid Drero
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How To Balance Youtube & College:COD AW Double DNA Bomb - Video
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DNA pioneer James Watson to sell Nobel Prize
Posted: at 3:47 pm
By Bryony Jones, CNN
updated 3:15 PM EST, Tue November 25, 2014
STORY HIGHLIGHTS
(CNN) -- DNA pioneer James Watson is to sell the Nobel Prize he won for his co-discovery of the double helix structure -- the building block of life.
The coveted gold medal is expected to go under the hammer for up to $3.5 million in a sale at Christie's in New York on December 4.
It will be the first time a Nobel Prize has been sold by a living recipient.
Watson, now 85, was awarded the medal, for work in the field of physiology or medicine, alongside fellow scientists Francis Crick and Maurice Wilkins in 1962.
Nobel Peace Prize: They didn't win either
Nobel Peace Prize: They didn't win either
Nobel Peace Prize: They didn't win either
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DNA pioneer James Watson to sell Nobel Prize
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Can Doggie DNA Tests Decode Your Mutts Makeup?
Posted: at 3:47 pm
Mixed breed. Mongrel. Roadside setter. A something-something. Dogs of uncertain provenance get called a lot of things. When the animal arrives at a shelter, staff usually can make only an educated guess about the dogs parentage.
Most of the dogs at my local animal control are assessed as pit mixes upon arrival including the three Ive adopted over the past 2 years. But a pit bull isnt a breed: its just a type of dog characterized by a short coat, muscular frame and broad, oversized head.
All three of my dogs clearly at least to my eyes showed signs of specific breeds somewhere in their heritage: Tall and snow white Pullo looks like the breed standard for an American Bulldog. Tyches body is svelte like a boxers and inky black like some Labs. And lanky, long-limbed Waldo sometimes bays like a hound, especially when treeing squirrels.
Guessing my dogs breeds was a fun parlor game, but I wanted more definitive answers. So I turned to science. And, well, lets just say its a good thing I didnt place any bets on what was in my dogs family trees.
Consumer-targeted dog breed identification testing has been around for about a decade, with Wisdom Panel 2.0, owned by Mars Veterinary, as the dominant player on the American market.
Wisdom Panel looks at 321 genetic markers in your dogs DNA to create a unique profile. That profile is fed into a program that assigns each ancestor from three generations parent, grandparent and great-grandparent into the best fit among more than 200 breeds in the Wisdom Panel database.
The doggie DNA test works differently than human ancestry tests, which typically trace both Y-chromosome DNA and maternally-inherited mitochondrial DNA back several generations. Instead, Wisdom Panel looks across the entire genome, not just on the sex chromosomes.
Wisdom Panel, like human ancestry tests, is more for the curious than for owners whose dogs are facing serious health problems. Medical DNA testing for dogs is much more focused and hunts for typically single-gene mutations that cause disease.
Urs Giger, a leading veterinary clinician and researcher, heads PennGen, at the University of Pennsylvanias School of Veterinary Medicine in Philadelphia. He says that though Wisdom Panel is less focused, it still has some medical value. Wisdom Panels purpose is to identify the breed or breed composite, which can be quite helpful information, says Giger. Knowing your dogs breeds can help your veterinarian tailor the treatment for a number of conditions, such as anemia, which may have different, breed-specific causes.
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Can Doggie DNA Tests Decode Your Mutts Makeup?
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Ultrafast, low-cost DNA sequencing technology a step closer to reality
Posted: at 3:47 pm
A team of scientists from Arizona State University's Biodesign Institute and IBM's T.J. Watson Research Center have developed a prototype DNA reader that could make whole genome profiling an everyday practice in medicine.
"Our goal is to put cheap, simple and powerful DNA and protein diagnostic devices into every single doctor's office," said Stuart Lindsay, an ASU physics professor and director of Biodesign's Center for Single Molecule Biophysics. Such technology could help usher in the age of personalized medicine, where information from an individual's complete DNA and protein profiles could be used to design treatments specific to their individual makeup.
Such game-changing technology is needed to make genome sequencing a reality. The current hurdle is to do so for less than $1,000, an amount for which insurance companies are more likely to provide reimbursement.
In their latest research breakthrough, the team fashioned a tiny, DNA reading device a thousands of times smaller than width of a single human hair.
The device is sensitive enough to distinguish the individual chemical bases of DNA (known by their abbreviated letters of A, C, T or G) when they are pumped past the reading head.
Proof-of-concept was demonstrated, by using solutions of the individual DNA bases, which gave clear signals sensitive enough to detect tiny amounts of DNA (nanomolar concentrations), even better than today's state-of-the-art, so called next-generation DNA sequencing technology.
Making the solid-state device is just like making a sandwich, just with ultra high-tech semiconductor tools used to slice and stack the atomic-sized layers of meats and cheeses like the butcher shop's block. The secret is to make slice and stack the layers just so, to turn the chemical information of the DNA into a change in the electrical signal.
First, they made a "sandwich" composed of two metal electrodes separated by a two-nanometer thick insulating layer (a single nanometer is 10,000 times smaller than a human hair), made by using a semiconductor technology called atomic layer deposition.
Then a hole is cut through the sandwich: DNA bases inside the hole are read as they pass the gap between the metal layers.
"The technology we've developed might just be the first big step in building a single-molecule sequencing device based on ordinary computer chip technology," said Lindsay.
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Ultrafast, low-cost DNA sequencing technology a step closer to reality
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A Hybrid Vehicle That Delivers DNA
Posted: at 3:47 pm
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Newswise BUFFALO, N.Y. A new hybrid vehicle is under development.
Its performance isnt measured by the distance it travels, but rather the delivery of its cargo: vaccines that contain genetically engineered DNA to fight HIV, cancer, influenza and other maladies.
Described recently in the Proceedings of the National Academy of Sciences, the technology is a biomedical advancement that could help unleash the potential of DNA vaccines, which despite two decades of research, have yet to make a significant impact in the treatment of major illnesses.
The technology that were developing could help take immunization to the next level, said Blaine A. Pfeifer, PhD, an associate professor in the Department of Chemical and Biological Engineering in the School of Engineering and Applied Sciences at the University at Buffalo.
Pfeifer, the studys lead author, added: By improving the delivery of DNA vaccines, we can potentially harness the human immune system in new ways to fight everything from the flu and herpes to HIV and cancer.
Conventional vaccines, like those used to fight polio and smallpox, are typically composed of an agent that contains weakened or killed forms of the disease-causing microbe. The agent prompts the immune system to recognize the agent as foreign, destroy it, and keep a record of it so the immune system can more effectively fight it in the future.
While effective, some vaccines dont last, others can revert to dangerous forms and some are costly and time-consuming to develop. Furthermore, no effective vaccines exist for cancer, malaria and others diseases that kill millions of people worldwide annually.
DNA vaccines could address these problems.
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A Hybrid Vehicle That Delivers DNA
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A link between DNA transcription and disease-causing expansions
Posted: at 3:47 pm
PUBLIC RELEASE DATE:
25-Nov-2014
Contact: Alex Reid alexander.reid@tufts.edu 617-627-4173 Tufts University @TuftsUniversity
Medford/Somerville, Mass--Researchers in human genetics have known that long nucleotide repeats in DNA lead to instability of the genome and ultimately to human hereditary diseases such Freidreich's ataxia and Huntington's disease.
Scientists have believed that the lengthening of those repeats occur during DNA replication when cells divide or when the cellular DNA repair machinery gets activated. Recently, however, it became apparent that yet another process called transcription, which is copying the information from DNA into RNA, could also been involved.
A Tufts University study published online on November 20 in the journal "Cell Reports" by a research team lead by Sergei Mirkin, the White Family Professor of Biology at Tufts' School of Arts and Sciences, along with former graduate student Kartick Shah and graduate students Ryan McGuity and Vera Egorova, explores the relationship between transcription and the expansions of DNA repeats. It concludes that the active transcriptional state of a DNA segment containing a DNA repeat predisposes it for expansions. The print version of the study will be published on December 11.
"There are a great many simple repetitive motifs in our DNA, such as GAAGAAGAA or CGGCGGCGG," says Mirkin. "They are stable and cause no harm if they stay short. Occasionally, however, they start lengthening compulsively, and these uncontrollable expansions lead to dramatic changes in genome stability, gene expression, which can lead to human disease."
In their study, the researchers used baker's yeast to monitor the progress and the fundamental genetic machineries for transcription, replication and repair in genome functioning.
"The beauty of the yeast system is that it provides one with a practically unlimited arsenal of tools to study the mechanisms of genome functioning," says Mirkin. "We created genetic systems to track down expansions of the repeats that were positioned in either transcribed or non-transcribed parts of reporter genes."
After measuring the rate of repeat expansions in all these cases, the authors found that a repeat can expand under the condition when there is practically no transcription, but the likelihood of the expansion process is drastically (10-fold) higher when the reporter is transcriptionally active.
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A link between DNA transcription and disease-causing expansions
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Your chance for a Nobel prize — at a price
Posted: at 3:47 pm
STORY HIGHLIGHTS
(CNN) -- DNA pioneer James Watson is to sell the Nobel Prize he won for his co-discovery of the double helix structure -- the building block of life.
The coveted gold medal is expected to go under the hammer for up to $3.5 million in a sale at Christie's in New York on December 4.
It will be the first time a Nobel Prize has been sold by a living recipient.
Watson, now 85, was awarded the medal, for work in the field of physiology or medicine, alongside fellow scientists Francis Crick and Maurice Wilkins in 1962.
Nobel Peace Prize: They didn't win either
Nobel Peace Prize: They didn't win either
Nobel Peace Prize: They didn't win either
Nobel Peace Prize: They didn't win either
Nobel Peace Prize: They didn't win either
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Your chance for a Nobel prize -- at a price
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