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Category Archives: Technology

The Greatest Gene Editing Technology on the Planet? – Genetic Engineering & Biotechnology News

Posted: July 7, 2022 at 9:08 am

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Cas-CLOVER significantly reduces off-target risk with a paired gRNA, deactivated Cas fusion protein (dCas), and dimeric Clo051 nuclease. A proven technology for cell line development (CLD) and bioprocessing, agriculture, and synthetic biotechnology, Cas-CLOVER also features high efficiency in target cells and organisms coupled with simple and flexible design and technology licensing (Figure 1).

One common question is, Without Cas9, how do we design the guides? says David Norman, senior scientist at Demeetra. Some have struggled with other alternatives to Cas9 where less is known about guide design. Cas-CLOVER seamlessly works with your favorite design platforms and gRNA manufacturers.

Cas-CLOVERs flexible spacer between the two gRNAs required for Clo051dimerization enables target accessibility. In cells, yeast and plants, high activity between 12 and 32 base spacers is common. Ive never seen a sequence we couldnt target. Our guidance is to start with spacers of 1530 bases, Norman says. (See Figure 2 and Figure 3).

The end result is beneficially distinct from CRISPR-Cas9, because its a completely different nuclease. While Cas9 typically results in smaller blunt-end deletions, Clo051 yields larger deletions with four-base overhangs, Norman continues. Large deletions are easier to identify, cutting down workflow processes. Researchers have also observed higher knock-in efficiency with Cas-CLOVER using homology-directed repair (HDR) and non-homologous end joining (NHEJ).

Gene editing can improve biotherapeutics; the manufacturing of viral vectors; cultured meats and proteins; and even agriculture. However, economic barriers and FTO confusion have slowed commercial use. We want Cas-CLOVER applied for maximum ROI for our partners, says Jack Crawford, CEO at Demeetra. For established companies with large pipelines, an ideal license structure is much different than for CDMOs working on a cash-flow basis or start-ups looking to get to the next value inflection. Demeetra has established a flexible license framework for all situations. If Cas-CLOVER can help, we want to do the deal now and on mutually beneficial terms for licensees and, ultimately, society, Crawford adds.

Cas-CLOVER in plants is a growing success in both dicots and monocots. One such project is with Leena Tripathi at the International Institute of Tropical Agriculture (IITA), Kenya. Tripathi group and Demeetra collaborated to test Cas-CLOVER in banana plants. Delivering the Cas-CLOVER reagents to banana cell suspension and targeting the PDS gene resulted in the PDS knockout. This revealed the expected albino phenotype, and sequencing later confirmed large deletions associated with Cas-CLOVER (Figure 4).

We are very excited to improve the banana varieties preferred by farmers in Africa for disease-resistant bananas using Cas-CLOVER, Tripathi says. The gene edited banana with no foreign gene integration will not be regulated as a GMO in Kenya. The disease-resistant varieties will enhance banana production and increase the incomes of smallholder farmers in East Africa, where the banana is one of the major staple foods.

Engineering for disease resistance and delayed browning are next on the list. Traits for varieties that are sold locally in Africa will not be royalty bearing, while varieties that are exported such as Cavendish will be licensed by Demeetra. We have set up a robust process with Leenas group and are open to partnering with banana export companies, while providing unhindered value to African food security. Crawford says.

Unlike most traditional agricultural companies, Demeetra does not plan on providing seed or managing acreage. Instead, Cas-CLOVER is licensed for research that can convert to flexible commercial access. Clients can edit their target crop in-house or can use any CRO, including Demeetra, or academic group to create the edits they desire, Crawford says. Since we do not ourselves have an interest in any crop, other than for manufacturing cannabinoid drug candidates, we can be very creative with our license structureand the client owns all the IP created with the technology.

Imagine nearly 100% targeted editing with under 1% off-target risk. That is precisely what we are aiming for with our new Clo051 variants, says Corey Brizzee, strain engineering scientist at Demeetra. Through robust yeast gene editing and protein engineering capabilities, Demeetra has discovered hyperactive Clo051 mutants that reach 99% targeted editing as well as 10 times less cellular toxicity compared to Cas9 in yeast (Figure 1).

New hyperactive variants which Demeetra refers to as CLOVERx are expected to apply to all projects but will be especially important for organisms that require more resources such as plants and agricultural animals. Our licenses have always included future technology improvements; this is another benefit of partnering with Demeetra, Crawford concludes. These improvements to the platform are similar to updates to operating softwareimproving performance on a complimentary basis.

Visit us at http://www.demeetra.comto learn more about our technology, schedule time with one of our experts, or shop for reagents.

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Californias chronic technology woes will be probed – CalMatters

Posted: at 9:08 am

In summary

Californias state government has a sorry record on using information technology to make agencies more efficient, and a new audit aims to find out why.

Last months primary election was the latest test for a state computer system that is supposed to provide timely and complete data on campaign contributions, lobbying expenditures and other financial aspects of the political process.

Cal-Access, as its known, struggled to do what it was supposed to do, which surprises exactly no one who tries to use the system.

Its not a new problem. The shortcomings of the 23-year-old political reporting system have been known for years. The former secretary of state, Alex Padilla, once described Cal-Access as a Frankensteins monster of code that is in need of a complete rebuild and sponsored 2016 legislation to create a replacement.

Then-Gov. Jerry Brown, himself a former secretary of state, agreed that the system needed an overhaul and signed the legislation. A successor system was supposed to be ready within a few years, but it wasnt.

Last year, Padilla was appointed to the U.S. Senate. Shirley Weber, a Democratic assemblywoman from San Diego, was named as his successor and she more or less scrapped what Padilla had done on the Cal-Access Replacement System or CARS, as its called.

To ensure that the CARS project can fully meet its statutory obligations, the scheduled June 30, 2021, rollout of the project will be postponed, Weber said. Moving forward, the secretary of states office will assess the projects state of readiness so that on the date it goes live it will meet the expectations of the public, stakeholders and the regulated community.

Its another example of a syndrome that has plagued state government for years. While Californias Silicon Valley and other technology hubs may be global leaders in the development of information technology, its state government has been chronically incapable of implementing IT systems that work as promised.

One of the most spectacular IT failures was a meltdown in the Employment Development Departments handling of claims for unemployment insurance benefits from hundreds of thousands of California workers who lost their jobs due to pandemic-related shutdowns, compounded by approving billions of dollars in payments to fraudsters.

The long list of IT systems that that have failed, incurred huge cost overruns and/or were delayed for years is, or at least should be, especially embarrassing to Gov. Gavin Newsom. In 2013, he published a book, Citizenville: How to Take the Town Square Digital and Reinvent Government, predicting that technology would transform American democracy and end political gridlock.

Californias sorry record of IT failure raises the obvious question of why? Is it bureaucratic sclerosis? Is it an inability to define missions precisely enough for software engineers to design solutions? Do vendors overpromise results to pad their bills?

The state auditors office has identified managerial shortcomings in many specific projects, such as one dubbed FI$Cal, supposedly a comprehensive integration of financial data. However, theres never been an analysis of what obviously is a systemic procurement failure until now.

Last week, the Legislatures audit committee directed the auditors office to examine the entire IT procurement system, beginning with the Department of Technology, which was created several years back to solve the chronic problem.

State Assembly, District 74 (Costa Mesa)

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State Assembly, District 74 (Costa Mesa)

Time in office

2018present

Background

Small Business Owner

How she voted 2019-2020

Liberal Conservative

District 74 Demographics

Race/Ethnicity

Latino 17%

White 59%

Asian 19%

Black 1%

Multi-race 3%

Voter Registration

Dem 35%

GOP 35%

No party 25%

Other 4%

Campaign Contributions

Asm. Cottie Petrie-Norris has taken at least $2 million from the Party sector since she was elected to the legislature. That represents 34% of her total campaign contributions.

The audit was requested by Assemblywoman Cottie Petrie-Norris, an Irvine Democrat who chairs the Assembly Accountability and Administrative Review Committee.

The pandemic showed us the disastrous results of state IT systems that are overloaded, antiquated, and not ready for the task ahead, Petrie-Norris said. This audit request is a critically needed look at the technology systems Californians should be able to easily rely on every day to interact with their government and obtain vital services.

A long-overdue look.

CalMatters is a nonprofit newsroom and your tax-deductible donations help us keep bringing you and every Californian essential, nonpartisan information.

I read and support CalMatters to get beyond the PR spin, to see how California governments are serving or failing their goals.

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SINTX Technologies Acquires Technology Assessment and Transfer, Inc. – Business Wire

Posted: at 9:08 am

SALT LAKE CITY--(BUSINESS WIRE)--SINTX Technologies, Inc. (www.sintx.com) (NASDAQ: SINT) (SINTX or the Company), an original equipment manufacturer of advanced ceramics, announced the acquisition of Technology Assessment and Transfer, Inc. (TA&T; https://www.techassess.com/), significantly increasing SINTXs capabilities in the aerospace, defense, and biomedical markets.

We are excited to acquire TA&T and take another step towards diversifying and strengthening SINTX, said Dr. Sonny Bal, President and CEO of SINTX. TA&T will expand our use of advanced manufacturing technologies and introduce new ceramic material platforms to the SINTX portfolio. We expect the acquisition to bring immediate revenue to SINTX via TA&Ts well-established relationships with commercial partners and the U.S. government.

TA&T, based in Maryland, is a nearly 40-year-old advanced ceramics business that specializes in developing and commercializing a broad array of innovative materials for defense, biomedical, and industrial applications. The companys technologies and products include 3D printing of ceramic medical devices and heat exchangers, chemical vapor infiltration and deposition of complex fiber-reinforced ceramic-matrix composites, and hot pressing of transparent armor and other technical ceramics. TA&T has a long track record of successfully winning research contracts and grants from the U.S. government and commercializing its innovative technologies.

As an example of TA&Ts innovation, ceramic heater bodies developed, designed, and manufactured by TA&T are a part of the Sample Analysis on Mars (SAM) instrument suite on board the Curiosity Rover (https://mars.nasa.gov/msl/home/). These oven heater bodies were manufactured by TA&T using Ceramic Stereolithography, a form of 3D printing and additive manufacturing, and can withstand the extreme temperatures of more than 1,500F that are required to heat soil samples on Mars in hopes of detecting signs of life. TA&T was selected by NASA to make these parts because of the prohibitive cost of traditional manufacturing techniques.

Technology Assessment and Transfer is excited about the opportunity that the SINTX acquisition provides for product growth in commercial, aerospace, and medical applications, said Dr. Larry Fehrenbacher, Co-Founder and President of TA&T. The blend of federally-funded innovative technologies and SINTXs business acumen is a compelling synergistic formula for future success.

Dr. Mark Patterson, who worked with TA&T previously, and is currently Principal Scientist at Kratos SRE, commented that In my view, the acquisition of TA&T by SINTX represents a significant opportunity to leverage complementary cultures and capabilities in the areas of advanced ceramics and innovation. TA&T has a long history of developing unique processes and ceramic materials for space, defense and commercial markets, and the company was an early developer of additively manufactured ceramic components for new ceramic markets. SINTX has complementary capabilities in biomedical devices and ceramic armor, with access to capital markets and organizational skills that will greatly help to mature and transition these technologies. I am excited to see what will come from this promising synergy, and hope that we will get to experience more ceramic products transitioned to end users.

Ascendiant Capital Markets LLC served as the sole M&A Advisor on the transaction.

About SINTX Technologies, Inc.SINTX Technologies is an OEM ceramics company that develops and commercializes advanced ceramics for medical and non-medical applications. The core strength of SINTX Technologies is the manufacturing, research, and development of ceramics for external partners. The Company presently manufactures silicon nitride powders and components in its FDA registered, ISO 13485:2016 certified, and ASD9100D certified manufacturing facility.

For more information on SINTX Technologies or its advanced ceramics material platforms, please visit http://www.sintx.com.

About Technology Assessment and Transfer, Inc.Technology Assessment and Transfer, Inc. (TA&T) is a high technology small business that specializes in development of advanced, materials-oriented technologies for aerospace, defense, bio-medical and industrial applications. TA&T uses government research grants to support advanced technology research and development innovations and commercialize via limited production, technology licensing and cooperative partnerships. TA&T provides a host of services that includes 3D printing, PVD-CVD coatings, material processing-CMCs, CIP, PS, HP, HIP and material characterization for powders and finished parts-TGA/DSC, PSD. SA, Dilatometry, UV-VIS and FTIR transmission, haze and clarity.

Forward-Looking StatementsThis press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 (PSLRA) including, but not limited to, statements regarding SINTXs ability to achieve revenues through its operation of TA&T, to expand its use of advanced manufacturing technologies, and, to introduce new ceramic material platforms to the SINTX portfolio. Such forward-looking statements are subject to a number of risks and uncertainties that may cause actual results to differ from current expectations. Risks and uncertainties that may cause such differences include, among other things: integration of the businesses of each of SINTX and TA&T, SINTXs products may not prove to be as effective as other products currently being commercialized or to be commercialized in the future by competitors; risks inherent in manufacturing and scaling up to commercial quantities while maintaining quality controls; volatility in the price of SINTXs common stock; the uncertainties inherent in new product development, including the cost and time required to commercialize such product(s); market acceptance of our products once commercialized; SINTXs ability to raise funding and other competitive developments. Readers are cautioned not to place undue reliance on the forward-looking statements, which speak only as of the date on which they are made and reflect managements current estimates, projections, expectations, and beliefs. There can be no assurance that any of the anticipated results will occur on a timely basis or at all due to certain risks and uncertainties, a discussion of which can be found in SINTXs Risk Factors disclosure in its Annual Report on Form 10-K, filed with the Securities and Exchange Commission (SEC) on March 25, 2022, and in SINTXs other filings with the SEC. SINTX disclaims any obligation to update any forward-looking statements. SINTX undertakes no obligation to publicly revise or update the forward-looking statements to reflect events or circumstances that arise after the date of this report.

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Insights on the Connected Car Global Market to 2027 – by Technology, Connectivity Solutions, Service, End Market and Region – ResearchAndMarkets.com -…

Posted: at 9:08 am

DUBLIN--(BUSINESS WIRE)--The "Connected Car Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2022-2027" report has been added to ResearchAndMarkets.com's offering.

The global connected car market reached a value of US$ 62.83 Billion in 2021. Looking forward, the publisher expects the market to reach a value of US$ 156.6 Billion by 2027, exhibiting a CAGR of 16.44% during 2021-2027.

Companies Mentioned

Keeping in mind the uncertainties of COVID-19, we are continuously tracking and evaluating the direct as well as the indirect influence of the pandemic on different end use sectors. These insights are included in the report as a major market contributor.

Connected cars refer to vehicles that are equipped with internet connectivity and advanced communication technologies to facilitate the exchange of information via numerous communication channels. They are designed to offer improved vehicle performance, enhanced convenience to the users, and efficient interaction of the transport system with its surroundings to prevent road accidents and notify prompts regarding parking space availability.

They also provide real-time traffic alerts to the driver and alarm emergency services in case of an unfortunate circumstance. Along with this, these alerts and signals further aid in enhancing the overall traffic performance and road safety management while ensuring optimal driving comfort. The growing dependency on uninterrupted connectivity to access navigation services is providing a thrust to the market growth.

The market is primarily driven by the increasing demand for in-car safety solutions. In line with this, the widespread integration of connected cars with advanced driver-assistance systems (ADAS) for mapping road obstacles and anti-lock braking systems (ABS) to enable safe braking is expected to create a positive outlook for the market.

Moreover, the advent of 5G connectivity and the rising utilization of artificial intelligence (AI) and machine-to-machine (M2M) interconnectivity between multiple cars are favorably impacting the market. In line with this, continual developments in the manufacturing of advanced suspension systems are also providing an impetus to the market.

The market is further driven by the escalating popularity of luxury cars among individuals with high disposable income levels and the emergence of autonomous driving trends. Some of the other factors contributing to the market growth include rapid digitization across the automotive sector and extensive research and development (R&D) activities conducted by key players.

Key Questions Answered in This Report:

Key Topics Covered:

1 Preface

2 Scope and Methodology

3 Executive Summary

4 Introduction

4.1 Overview

4.2 Key Industry Trends

5 Global Connected Car Market

5.1 Market Overview

5.2 Market Performance

5.3 Impact of COVID-19

5.4 Market Forecast

6 Market Breakup by Technology

7 Market Breakup by Connectivity Solutions

8 Market Breakup by Service

9 Market Breakup by End Market

10 Market Breakup by Region

11 SWOT Analysis

12 Value Chain Analysis

13 Porters Five Forces Analysis

14 Price Analysis

15 Competitive Landscape

15.1 Market Structure

15.2 Key Players

15.3 Profiles of Key Players

For more information about this report visit https://www.researchandmarkets.com/r/9oasuz

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Insights on the Connected Car Global Market to 2027 - by Technology, Connectivity Solutions, Service, End Market and Region - ResearchAndMarkets.com -...

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Enchanted Technology Summer Festival 2022 – Portland State University

Posted: at 9:08 am

Join CETI (A Creative and Emergent Technology Institute) at the Portland State University School of Art + Design for a summer of collaborative learning, play, and creative experiments using cutting edge technologies (XR, creative code, smart tech), art and music to craft delightful and imaginative interactive objects, stories, spaces and experiences placed around the city. Summer classes include:

"Enchanted Objects" (July 18 to 25), where participants will create objects that make music, illuminate in response to stimulation, reveal hidden stories and spark imaginations.

"Augmented Storytelling" (August 1 to 12), which will encourage participants to create stories of our city and community using existing markers (such as stickers or statues), sparking real and imagined experiences that reveal new ways of seeing the world.

In "Interactive Murals/Interactive Installations" (August 8 to 23), students will create hybrid physical, digital and virtual images that respond to a person's presence, gestures and actions, revealing historical and speculative stories of our communities and spaces.

An information session will be held on Tuesday, July 12, 4:15 to 5:30 p.m.

Learn more and apply to participate.

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Enchanted Technology Summer Festival 2022 - Portland State University

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ANGELALIGN TECHNOLOGY INC. Wins Several Awards on Institutional Investor Magazine’s "2022 All-Asia Executive Team" – GlobeNewswire

Posted: at 9:08 am

Shanghai, China, July 06, 2022 (GLOBE NEWSWIRE) -- On June 23rd, ANGELALIGN TECHNOLOGY INC. was awarded the Most Honored Company in Institutional Investors poll of 2022 All-Asia Executive Team. Ranked second overall in the category of Health Care & Pharmaceuticals, the company was at the second place in other four individual awards, namely Best CEO, Best IR Professional, IR Program, and ESG.

This year, a total of 1,612 listed companies across 18 sectors were nominated in the Institutional Investor 2022 All-Asia Executive Team Poll. Though it was the first time that ANGELALIGN TECHNOLOGY INC. was rated in the poll since its listing on the Hong Kong Stock Exchange in June 2021, the company received various awards from the Institutional Investor, which highlights the capital market's high recognition on ANGELALIGN TECHNOLOGY INC. in corporate governance and investor relations etc.

ANGELALIGN TECHNOLOGY INC. is a leading clear aligner treatment solution provider in China. Since established, the Company has been immersing itself in digital orthodontics by focusing on the needs of dental professionals and clinical scenarios. It has been developing industry-leading and proprietary technological capabilities in five disciplinary fields, including clinical stomatology, biomechanics, material science, computer science and intelligent manufacturing technology. With the help of continuously refined products and technological services, the company has been empowering doctors comprehensively. In face of an array of challenges from COVID-19 and weak consumption etc over the past year, ANGELALIGN TECHNOLOGY INC. maintained an agile forecasting on the market and quickly enforced coping strategies to seize opportunities at its best while devoted to long-term business growth. The Company achieved approximately 183,200 case shipments, served around 25,000 dental professionals throughout the year, gaining high-quality growth and breakthroughs, and further consolidating its leading position in Chinas clear aligner market. According to the report by China Insights Consultancy, measured by the delivered case shipments in 2021, ANGELALIGN TECHNOLOGY INC. harvested a highest market share of 41.1% in Chinas clear aligner industry.

ANGELALIGN TECHNOLOGY INC. Wins Several Awards on Institutional Investor Magazine's "2022 All-Asia Executive Team"

Institutional Investor is one of the most influential financial magazines for global investment institutions and has enjoyed high credibility since its publication for more than 50 years. The magazine carries out management team survey for listed companies all over the world annually. Only certified financial professionals own the rights to vote, making the ranking of Institutional Investor one of the most authoritative rankings in the capital market, and its ranking results become a global investment trendsetter, recognized by buy-side investors and sell-side institutions.

This year, a total of 4,854 buy-side professionals and 670 sell-side analysts participated in this survey. Among them, the number of voters increased by 35% compared to 2021, reaching a record high, with an estimated $2 trillion in Asia (ex-Japan) equities. The nominated listed companies were rated on several core areas as below:

1. Services & Communications

Business & Market Knowledge

Accessibility of Senior Execs

IR Team Authority & Credibility

Responsiveness

Roadshows/Conferences/Meetings

Earnings Calls

2. Financial Disclosure

Timing to Market (Timeliness)

Consistency

Granularity

3. CEO

Communication

Credibility

Leadership

4. CFO

Capital Allocation

Communication

Financial Stewardship

5. IR Professional

Overall performance

ANGELALIGN TECHNOLOGY INC. has been committed to helping doctors achieve stable, easy, fast, and accurate diagnosis and treatment through products and technological services driven by digital technologies, and bringing people healthy, straightened teeth and brighter smiles. ANGELALIGN TECHNOLOGY INC. specialized in digital dentistry, is keen to work with doctors to generate cutting-edge innovations based on doctors clinical feedback and patients needs. Furthermore, with continuous efforts in innovation and evolution, the company relies on its interdisciplinary R&D capabilities - it has built reliable technological and data platforms to provide more targeted and reliable solutions for complex malocclusion cases. At the same time, ANGELALIGN TECHNOLOGY INC. effectively implements international standard-based corporate governance, and has a hard-working, farsighted, and experienced management team.

As the "First Stock of Orthodontics in China", ANGELALIGN TECHNOLOGY INC. boasts a management team that keeps taking a proactive and holistic attitude, firmly adheres to the principle of "Customer first and upholds the mission of "Use technology to create brighter smiles to influence the world". Under the two-wheel drive of medical science as the essence and technological innovation as the focus, the Company will give full play to its core advantages to stimulate the upstream and downstream of the industrial chain and break the existing technological barriers, in the meantime, committed to remaining as the pioneer in the field of digital orthodontics in China and promoting the growth, transformation and sustainable development of China's digital orthodontic ecosystem.

Company: ANGELALIGN TECHNOLOGY INC.

Email: investor@angelalign.com

Website: http://www.angelalign.com

Tel: (86) 21-56561919

City: Shanghai

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ANGELALIGN TECHNOLOGY INC. Wins Several Awards on Institutional Investor Magazine's "2022 All-Asia Executive Team" - GlobeNewswire

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Divergent Technologies Strengthens Capital Resources with $60 Million Loan Facility Led by Horizon Technology Finance and $20 Million Line of Credit…

Posted: at 9:08 am

LOS ANGELES, July 7, 2022 /PRNewswire/ -- Divergent Technologies Inc. ("Divergent"), the company that has developed the world's first end-to-end digital production system to revolutionize industrial-scale manufacturing, announced today that it has closed a new $60 million venture loan facility led by Horizon Technology Finance Corporation (NASDAQ: HRZN) ("Horizon"), and a new $20 million revolving line of credit provided by Bridge Bank, a division of Western Alliance Bank (NYSE: WAL) ("Bridge Bank"). The new facilities follow Divergent's successful $160 million Series C funding earlier this year.

Under the terms of the venture loan agreement, Horizon, a leading specialty finance company that provides capital in the form of secured loans to venture capital backed companies in the technology, life science, healthcare information and services, and sustainability industries, funded $15 million of the initial draw from the venture loan facility, and a private investment vehicle managed by Horizon Technology Finance Management LLC, Horizon's adviser, funded $5 million. The venture loan facility provides up to an additional $40 million of funding to Divergent upon meeting certain milestones.

Under the terms of the line of credit, Bridge Bank, whose Technology Banking Group provides financing solutions to venture capital backed technology companies at all stages of their life cycle, established a $20 million line of credit with Divergent whowill use the funds for growth and working capital purposes.

Divergent is building a global manufacturing infrastructure platform for the next generation industrial economy, with a current focus on the automotive industry. Its full-stack, state-of-the-art Divergent Adaptive Production System ("DAPS") simultaneously aids in automating design, additive manufacturing (3-D printing) and assembling complex vehicle structures. As a result, the DAPS platform significantly reduces development and production timelines, and Divergent has established a world-class pipeline of OEM customers.

"We are pleased to receive support from Horizon and Bridge Bank as we continue to revolutionize complex industrial manufacturing, initially with automobiles and over time with aerospace and defense," said Kevin Czinger, lead inventor, founder and Chief Executive Officer of Divergent. "DAPS makes it possible for the first time for manufacturers to forego the capital-intensive static design system they have been accustomed to for over a century, and utilize a variable cost flexible design system that is significantly more efficient. Through this added efficiency, DAPS radically reduces the impact of manufacturing on the environment, thereby making a meaningful contribution to global sustainability."

"Divergent is changing the game for manufacturing vehicles, with their DAPS end-to-end platform providing manufacturers with unmatched cost savings and flexibility," said Gerald A. Michaud, President of Horizon. "With over 500 patent filings, DAPS is a cutting-edge approach that enables Divergent customers to create new product models much more quickly and efficiently. We are excited to support Divergent's growth and expansion."

"Divergent is radically transforming auto manufacturing economics and environmental impact, and it is exciting to see Divergent deliver a solution that addresses system level challenges," said Mike Lederman, Senior Managing Director in Bridge Bank's Technology Banking Group. "Divergent is rethinking the manufacturing process for the auto industry and we are pleased to help support the company's evolution."

BayCross Capital Group acted as the placement agent on the debt (the securities portion of which was conducted via StillPoint Capital, LLC Member FINRA/SIPC).

About Divergent

Divergent harnesses additive manufacturing to unleash innovation in automotive manufacturing. Their breakthrough technology platform transforms the economics and environmental impact of designing and manufacturing complex structures such as cars. Divergent's planet-saving manufacturing approach can be used for volume manufacturing without costly, traditional tooling and capital expenses, enabling manufacturers to quickly iterate and invent new vehicle models for competitive advantage. For more information, please visitwww.divergent3d.com.

About Horizon Technology Finance

Horizon Technology Finance Corporation (NASDAQ: HRZN) is a leading specialty finance company that provides capital in the form of secured loans to venture capital backed companies in the technology, life science, healthcare information and services, and sustainability industries. The investment objective of HRZN is to maximize its investment portfolio's return by generating current income from the debt investments it makes and capital appreciation from the warrants it receives when making such debt investments. Horizon Technology Finance Management LLC is headquartered in Farmington, Connecticut, with a regional office in Pleasanton, California, and investment professionals located in Portland, Maine, Austin, Texas, and Reston, Virginia. To learn more, please visit horizontechfinance.com.

About Bridge Bank

Bridge Bank, a division of Western Alliance Bank, Member FDIC, helps business clients realize their ambitions. Founded in 2001 in Silicon Valley, Bridge Bank offers a better way to bank for small to mid-market businesses across many industries, as well as emerging technology companies and the private equity community. Geared to serving both venture-backed and non-venture-backed companies, Bridge Bank delivers a broad scope of financial solutions, including startup banking, capital, equipment and working capital credit facilities, venture debt, treasury management, asset-based lending, SBA and commercial real estate loans and a full line of international products and services. Based in San Jose, Bridge Bank has 15 offices in major markets across the country, along with Western Alliance Bank's powerful array of specialized financial services. Western Alliance Bank is the primary subsidiary of Phoenix-based Western Alliance Bancorporation, with more than $60billion in assets. Western Alliance is #2 best-performing of the 50 largest public U.S. banks in the S&P Global Market Intelligence listing for 2021 and ranks high year after year on the Forbes list of "America's Best Banks." For more information, visit Bridge Bank online.

Contacts:

For Horizon Technology Finance

For Divergent

Investor Relations:

Public Relations:

ICR

DKC

Garrett Edson

Sean F. Cassidy

[emailprotected]

[emailprotected]

(860) 284-6450

(212) 981-5233

Media Relations:

ICR

Chris Gillick

[emailprotected]

(646) 677-1819

SOURCE Horizon Technology Finance Corporation

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Divergent Technologies Strengthens Capital Resources with $60 Million Loan Facility Led by Horizon Technology Finance and $20 Million Line of Credit...

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Boston Red Sox using technology to assist their minor league teams – WFXRtv.com

Posted: at 9:08 am

SALEM, Va. (WFXR) The Boston Red Sox are always looking for ways to make their players better on and off the field especially with their minor league affiliates. Salem Red Sox general manager Allen Lawrence says the technology installed at Salem Memorial Ballpark is helping the players take their game to the next level.

We just recently had 24 cameras installed around the ballpark fans will see them come out here. But it was done in about two weeks its by a company called KinaTrax and its really a state of the art program that collects data on both the pitcher and the batter to help measure performance and can potentially avoid that player getting injured down the road, said Lawrence.

Originally installed by the Boston Red Sox Kinatraxs Algorithim can evaluate a players performance in near real time the markerless motion capture technology data allows for athletes to adjust their mechanics so that the red sox can get the best results out of the player on the field.

Technology has just changed sports in general and even more specifically baseball and so to have that knowledge and to have the ability to look ahead and see what a player might be doing incorrectly in terms of the form to avoid injury down the road I think speaks volumes to where the game is going and the fact that its in our facility here in Salem I think it just speaks to how important these players on the field are to the success of the Boston Red Sox somewhere down the road, said Lawrence.

For Lawrence player development is the top priority. You know the analytics in the game of baseball has really changed the sport over the last 10-15 years and this was system that was in stalled by the Boston Red Sox player development and keeping players healthy is obviously something that is very important to them so were lucky to have it here in Salem, said Lawrence. Lawrence said the technology has continued to help many of the players especially those who have currently moved up through Red Sox minor league system that may one day get the opportunity to play in the big show at Fenway Park

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DXC and Manchester United Stand ‘Shoulder to Shoulder’ in Multiyear Technology Partnership – PR Newswire

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Through the agreement, DXC will become principal partner of Manchester United focussed on the club's digital transformation and innovation. As principal shirt sleeve partner, DXC will have a global presence on the shoulder of the team's home, away and third kits. DXC will also become a partner of Manchester United Foundation, collaborating on the care it gives to the community.

"We are proud to welcome DXC as our principal partner for digital transformation, Manchester United Foundation and shirt sleeve in this exciting new era for the club," said Victoria Timpson, Manchester United's CEO of Alliances and Partnerships. "We are two organizations with a shared belief in the power of technology to win."

As one of the world's most globally recognized sports teams, Manchester United will work with DXC to become more data driven and optimize its digital offering to fans, helping to improve the way they engage and interact with the club.

"Through this partnership, Manchester United is turning to DXC for its experience in enterprise transformation as it strives to engage fans and inspire young people," said Chris Drumgoole, Chief Operating Officer, DXC Technology. "Whether it's running one of the most popular and successful sports teams in the world, or transforming business for Fortune 500 organizations, Manchester United and DXC are experts in running mission-critical activities. We stand united in delivering excellence."

The agreement, which commences July 2022, covers the following areas:

Manchester United's Digital PresenceDXC willdeliver and develop Manchester United's digital presence including the club's website and media platforms, bringing a global community of 1.1 billion fans and followers closer to the heart of the club.Starting immediately, DXC will manage Manchester United's app, which has users in 214 global territories and is the top downloaded sports app in 68 global markets. For example, DXC will streamline analytics data helping the club to deliver a more personalized experience for fans across the club's digital channels.

Data DrivenWith its experience in data analytics and engineering, DXC will help Manchester United to harness the power of datato enhance fan experience and certain business operations. In a first step, DXC and United will deliver a new data platform that will aggregate data across the club and enable new insights to inform strategic business planning and performance.

Partner to Manchester United FoundationDXC will also become the Presenting Partner of Manchester United Foundation. The partnership will focus on how technology can have a positive impact on people, the environment, and society, working together to educate and inspire a new generation of STEM students, through digital workshops, programs and in-person seminars.

Digital Transformation RoadmapDXC and Manchester United will work together to set a digital vision and strategy to help the club benefit from powerful emerging technologies as it prepares for opportunities of tomorrow. For example, DXC will work with the Man Utd Academy to support coaching staff with data analysis, tracking and reporting technologies.

Shirt Sleeve PartnerAs principal shirt sleeve partner for the 2022/23 season, DXC will be visible on the club's home, away and third kit, for the men's, women's and youth teams, receiving worldwide brand exposure to football's expansive global audience. DXC joins Teamviewer and adidas as principal partners on the new kit which will be launched later this week.

"DXC's technological expertise will help put Manchester United at the forefront of digital transformation, providing effective ways of working and new and exciting opportunities to interact with fans. The possibilities are endless, and we are looking forward to working with DXC on our future digital offerings," added Victoria Timpson.

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About DXC TechnologyDXC Technology (NYSE: DXC) helps global companies run their mission critical systems and operations while modernising IT, optimising data architectures, and ensuring security and scalability across public, private and hybrid clouds. The world's largest companies and public sector organisations trust DXC to deploy services across the Enterprise Technology Stack to drive new levels of performance, competitiveness, and customer experience.Learn more about how we deliver excellence for our customers and colleagues atDXC.com.

About Manchester UnitedManchester United is one of the most popular and successful sports teams in the world, playing one of the most popular spectator sports on Earth. Through our 144-year football heritage we have won 66 trophies, enabling us to develop what we believe is one of the world's leading sports and entertainment brands with a global community of 1.1 billion fans and followers. Our large, passionate and highly engaged fan base provides Manchester United with a worldwide platform to generate significant revenue from multiple sources, including sponsorship, merchandising, product licensing, broadcasting and matchday initiatives which in turn, directly fund our ability to continuously reinvest in the club.

SOURCE DXC Technology Company

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DXC and Manchester United Stand 'Shoulder to Shoulder' in Multiyear Technology Partnership - PR Newswire

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WANdisco Recognized as Finalist of 2022 Microsoft Rising Azure Technology Partner of the Year – PR Newswire

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The data activation company recognized out of over 3,900 nominations across more than 125 countries

SAM RAMON, Calif., July 7, 2022 /PRNewswire/ -- WANdisco, the data activation company, has been recognized as a finalist of the 2022 Microsoft Rising Azure Technology Partner of the Year Award. The company was honored among a global field of top Microsoft partners for demonstrating excellence in innovation and implementation of customer solutions based on Microsoft technology.

"This recognition celebrates the continued successful collaboration between WANdisco and Microsoft Azure. Together, we have supported cloud migrations, implementations, and digital transformations of enterprises around the world," said Chris Cochran,VP Cloud Alliances at WANdisco. "Our innovative and turnkey integration with Microsoft continues to deliver exceptional speed, scale, and security for organizations migrating enterprise-scale datasets to the Azure cloud. As we celebrate this milestone achievement, our team is more encouraged than ever to continue delivering exceptional data activation services to our customers alongside Microsoft."

The Microsoft Partner of the Year Awards recognize Microsoft partners that have developed and delivered outstanding Microsoft-based applications, services and devices during the past year. Awards were classified in various categories, with honorees chosen from a set of more than 3,900 submitted nominations from more than 100 countries worldwide. WANdisco was recognized for providing outstanding solutions and services while natively integrated into Azure.

"I am honored to announce the winners and finalists of the 2022 Microsoft Partner of the Year Awards," said Nick Parker, Corporate Vice President of Global Partner Solutions at Microsoft. "These partners were outstanding among the exceptional pool of nominees and I'm continuously impressed by their innovative use of Microsoft Cloud technologies and the impact for their customers."

The recognition as a finalist of the 2022 Microsoft Rising Azure Technology Partner of the Year Award continues a landmark year for WANdisco. Earlier this year, the company launched WANdisco Edge to Cloud, an offering that supports enterprises in activating IoT and sensor data moving it from edge environments to the cloud to support AI and ML initiatives and unleash business value. Built on WANdisco's Data Activation Platform, Edge to Cloud extends WANdisco's data activation capabilities beyond traditional Hadoop to cloud migrations to support enterprise IoT initiatives.

Microsoft Partner of the Year Awards are announced annually prior to the company's global partner conference, Microsoft Inspire, which will take place on July 19-20 this year.

About WANdisco

WANdisco is the first and only data activation platform for accelerating digital transformation at scale. WANdisco makes infinite data actionable across clouds and enterprises in real time. WANdisco customers unleash the business value of the cloud with zero downtime, data loss, or disruption to fuel AI and machine learning, create new services, and transform businesses. For more information about WANdisco, visit http://www.wandisco.com

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WANdisco Recognized as Finalist of 2022 Microsoft Rising Azure Technology Partner of the Year - PR Newswire

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