Category Archives: Progress

New York, New York--(Newsfile Corp. - August 31, 2020) - NanoViricides, Inc. (AMEX: NNVC) (the "Company") a global leader in the development of highly effective antiviral therapies based on a novel nanomedicines platform, has been the focus of recent coverage on leading financial news website and publisher, Small Caps Daily. NanoViricides' progress on developing a therapy to combat COVID-19 and also addressing the existing, global concern of how to get kids back to their classrooms, were two of the major topics covered in the Small Caps Daily article. Globally, nearly 850,000 lives have already been lost due to COVID-19, so it is very promising that NanoViricides' drug candidates showed strong effectiveness in the animal model as compared to remdesivir and have also outperformed favipiravir in its cell culture studies. NanoViricides has successfully carried out a safety and tolerability study on rats and the excellent results have now cleared the way for NanoViricides for moving forward to human clinical trials.

Key Takeaways from the SmallCapsDaily article featuring NanoViricides:

For more insight into NanoViricides, Inc., and to continue reading the Small Caps Daily featured article, please click here: https://smallcapsdaily.com/nanoviricides-working-to-get-kids-back-to-school-safely/.

About NanoViricides, Inc.

NanoViricides, Inc. (www.nanoviricides.com) is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHV-101 with its first indication as dermal topical cream for the treatment of shingles rash. The Company is in the process of completing an IND application to the US FDA for this drug candidate. The Company cannot project an exact date for filing an IND because of its dependence on a number of external collaborators and consultants, and the effects of recent COVID-19 restrictions.

The Company is also developing drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis, H1N1 swine flu, H5N1 bird flu, seasonal Influenza, HIV, Hepatitis C, Rabies, Dengue fever, and Ebola virus, among others. NanoViricides' platform technology and programs are based on the TheraCour nanomedicine technology of TheraCour, which TheraCour licenses from AllExcel. NanoViricides holds a worldwide exclusive perpetual license to this technology for several drugs with specific targeting mechanisms in perpetuity for the treatment of the following human viral diseases: Human Immunodeficiency Virus (HIV/AIDS), Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Rabies, Herpes Simplex Virus (HSV-1 and HSV-2), Varicella-Zoster Virus (VZV), Influenza and Asian Bird Flu Virus, Dengue viruses, Japanese Encephalitis virus, West Nile Virus and Ebola/Marburg viruses. The Company has executed a Memorandum of Understanding with TheraCour that provides a limited license for research and development for drugs against human coronaviruses. The Company intends to obtain a full license and has begun the process for the same. The Company's technology is based on broad, exclusive, sub-licensable, field licenses to drugs developed in these areas from TheraCour Pharma, Inc. The Company's business model is based on licensing technology from TheraCour Pharma Inc. for specific application verticals of specific viruses, as established at its foundation in 2005.

Forward-looking Statements

This press release contains forward-looking statements that reflect the Company's current expectation regarding future events. Actual events could differ materially and substantially from those projected herein and depend on a number of factors. Certain statements in this release, and other written or oral statements made by NanoViricides, Inc. are "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors which are, in some cases, beyond the Company's control and which could, and likely will, materially affect actual results, levels of activity, performance or achievements. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these forward-looking statements, even if new information becomes available in the future. Important factors that could cause actual results to differ materially from the company's expectations include, but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securities and Exchange Commission and other regulatory authorities. Although it is not possible to predict or identify all such factors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricide is safe and effective; successful development of our product candidates; our ability to seek and obtain regulatory approvals, including with respect to the indications we are seeking; the successful commercialization of our product candidates; and market acceptance of our products. FDA refers to US Food and Drug Administration. IND application refers to "Investigational New Drug" application. CMC refers to "Chemistry, Manufacture, and Controls".

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Excerpt from:

Small Caps Daily Features NanoViricides' Progress on Developing a Therapy To Help Kids Return To School Safely - Yahoo Finance

SCU Lighting Complex Fires may burn for weeks

The SCU Lightning Complex Fires are now the third largest in the state's history.

SANTA CRUZ, Calif. (KTVU) - The Bay Area has been devastated by several major wildfires around the region, from the Santa Cruz mountains to Lake Berryessa.

Cal Fire said many of them were sparked by a "lightning siege" or dry lightning strikes that started on Aug. 15. The fires have become some of the largest in California history.

The wildfires have been blamed for multiple deaths, the destruction of hundreds of homes, and an extended period of unhealthy air in many parts of the Bay Area.

RELATED: See where wildfires are burning in the Bay Area

Thousands of residents who were evacuated from their homes have been allowed to return as fire crews continue to gain ground on the wildfires and containment grows.

MAP - August 20, 2020. The Meyers and Wallbridge fires are burning near the Sonoma County Coast. The LNU Lightning Complex fire is made up of 7 fires in Napa, Sonoma, Solano, Lake and Yolo Counties. The SCU Lightning Complex fire is the combination o

Here are the latest details about the size and damage from each blaze:

LNU Lightning ComplexWhere: Sonoma, Napa, Solano, and Lake countiesSize: 375,209 acresContainment: 63%Injuries: 4 civiliansFatalities: 3 in Napa County; 2 in Solano CountyStructures Destroyed: 1,209Structures Threatened: 5,378Structures Damaged: 193

RELATED: Evacuation orders and warnings for Bay Area's major wildfires

CZU Lightning ComplexWhere: Santa Cruz and San MateocountiesSize: 84,860 acresContainment: 39%Injuries: 1 civilianFatalities: 1 personStructures Destroyed: 1,361 in total (of that 861 were homes)Structures Threatened: 6,759Structures Damaged: 132

SCU Lightning ComplexWhere: Portions of Alameda, Contra Costa, Santa Clara, San Joaquin, and Stanislaus countiesSize: 383,157 acresContainment: 60%Injuries: 2 civilians, 3 first respondersFatalities: 0 personStructures Destroyed: 40Minor structures destroyed: 64Structures Threatened: 20,065Structures Damaged: 18

The LNU, CZU, and SCU wildfires have burned a combined 843,226 acres.

Woodward FireWhere: Marin CountySize: 3,269 acresTotal Personnel on fire: 585Crews: 14Engines: 37Helicopters: 5

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Progress continues on wildfires burning across Bay Area - KTVU San Francisco

Ohio first lady Fran DeWine is pleased to announce amazing progress in reaching young Ohio readers in the Ohio Governors Imagination Library (OGIL) Programs first year.

Now, 206,463 Ohio children from birth to age 5 are enrolled to receive a free Imagination Library book in the mail every single month. The program is currently offered countywide to children in 78 of Ohios counties, with an additional three Crawford, Van Wert and Mercer launching the OGIL Program in September.

Thanks to dedicated Ohio lawmakers, who are investing in our kids with matching funding, and our wonderful local partners, the Ohio Governors Imagination Library has made outstanding progress in its first year, Mrs. DeWine said. But we still have more work to do. Mike and I look forward to the day that every young child in Ohio no matter what city, county, village or township that child lives in has access to the Ohio Governors Imagination Library books.

Last summer, the Dolly Parton Imagination Library Program was available in pockets of Ohio when the Ohio Governors Imagination Library partnered with the Dolly Parton program. In August 2019, 93,483 children were enrolled.As of September 2020, enrollment will more than double to 206,463.

I really enjoyed visiting with our local partners and families in 16 Ohio counties between January and March of this year, Mrs. DeWine said. Of course, that was before the COVID-19 pandemic. But weve continued working to find county partners during these recent months, because we know this program works.

Young children are excited to receive the book each month in the mail, which is addressed to them. And just having these books in the home promotes a love of learning and family bonding that we know adds up to preparing children for kindergarten. I encourage all Ohio children to sign up for these free books. Only seven Ohio counties Ashland, Columbiana, Lake, Ottawa, Richland, Sandusky and Seneca remain without a countywide program.

Parents and caregivers can sign up children atwww.OhioImaginationLibrary.org.

For more on the Imagination Library program in Highland County, see the article at: https://highlandcountypress.com/Content/In-The-News/In-The-News/Article/Ohio-first-lady-Fran-DeWine-Ohio-s-Electric-Cooperatives-announce-official-launch-of-Ohio-Governor-s-Imagination-Library-in-Highland-County/2/20/55881.

Read more:

First lady Fran DeWine announces first-year progress on Ohio Governor's Imagination Library Program - The Highland County Press

A cold front has been tracking through the region and this will continue to keep some clouds and the slim chance for a shower or storm around into the evening.

The boundary will be sitting just to the south of us late in the day so we could see a few storms lift into Southern Kansas this evening.

In the heating of the day and with a little more instability down into Oklahoma/Eastern Kansas, a couple of strong to severe storms are possible.

A Severe T-Storm Watch is in effect for Chautauqua Co. until 11 PM. A Marginal Risk is in place east of the metro through into tonight but the bulk of activity will be south and east of us.

Hail and gusty winds are the main hazards. Overnight, the shot for showers and storms upticks once again as our next disturbance moves in from the west.

This wave will bring more widespread moisture into the day on Tuesday. Temps will start of cooler than average tomorrow, with some spots in the 50s in Northwestern Kansas.

The front will remain stalled just to our south on Tuesday and as this impulse tracks in, expect scattered showers and storms through the day.

Highs will be impacted by the clouds and northerly flow, only topping out in the 70s and 80s.

A lingering shower or storm is possible Wednesday as this wave tracks eastward. High pressure will build in bringing a quieter mid-week with comfortable conditions.

Another cold front moves in Thursday, but this one is looking to come through dry, with forcing not expected to be that impressive. It will keep us seasonably cool, with highs in the mid-80s by Friday.

The heat starts to ramp up during the first weekend of September ahead of a more potent cold front that is slated to move through late Sunday. Isolated shower and storms will be possible but right now, the bulk of the moisture looks to be north of the viewing area. Temps will take a tumble from the 90s to the 70s/80s heading into next week.

Have a great night!

-Meteorologist T.J. Springer

Go here to see the original:

T.J.s Forecast: Cooler and unsettled as we progress into September - KSN-TV

Black artists are painting murals on Indianapolis businesses that have been boarded up after riots in late May. Three talk about their work. Indianapolis Star

Corrections & clarifications: An earlier version of this story incorrectly stated the manner of George Floyd's death.

The Monday after George Floyd was killed inpolice custody in Minneapolis, Turae Dabney was on a staff call. She had yet to process what happened to George Floyd, and speaking about her everyday reality as a Black woman in front of faces that didnt look like hers was overwhelming.

I didnt realize how much I had been carrying for so long, she said.

Her colleagues asked her how their organization should respond.

Dabney didnt know.

I need a minute, she told them.

Dabney realized where she sat as the executive director of People for Urban Progress, a design organization centering civic sustainability, and the power she had.

I had to step back and think about how I could use my platform to continue this conversation, she said.

But she wanted more than a social media post about racism.

Our response cant be superficial because this is not a superficial issue, she said. Its systemic.

A model wears a T-shirt from People for Urban Progress's new Ignitor line. Artist Byron Elliott designed the T-shirt to represent racial unity.(Photo: People for Urban Progress)

Then she got the idea for the Ignitor line, which launchedthis month, and features backpacks made from repurposed materials and T-shirts depicting unity. Part of the sales from the line will go to a new PUP fellowship to support inclusivity in the Indianapolis design community.

PUP wanted to emphasize underrepresented voices in its new line and reached out to Byron Elliott, a Black artist and the founder of the faith-based lifestyle brand Blacksheep Collective, to design the T-shirt.

Elliott said his design was inspired by the national conversation about racial inequity. In his community, Elliott has seen Black people suffer from systemic oppression and both overt and covert racism.Now that cellphones can captureproof of police brutality, he said, the reality of racial inequity is undeniable.

When youre faced with proof and with truth, you have two choices, he said. You can ignore it and go back to whats comfortable for you. Or you can do something about it.

The T-shirt he designed is his way of doing something to promote empathy and change, he said.

This is my way of protest, Elliott said. This is how I start a conversation.

A T-shirt from People for Urban Progress's new Ignitor line is draped over a mannequin. Artist Byron Elliott designed the T-shirt to represent racial unity.(Photo: People for Urban Progress)

The T-shirt depicts two hands of different shades coming together to form a heart. In the center of the heart is the Indianapolis flag. Elliott said the illustration conveys the importance of recognizing and respecting differences in one another while seeing the similarities.

Were all human, and we love and fear and have families and are trying to get by, he said. This shirt is designed to promote that, to help us see each other as human beings and brothers and sisters trying to share this planet.

When someone sees another person wearing the T-shirt, Elliott said he hopes they challenge themselves to ask difficult questions about race and to continue the conversations about race Elliott wants to spark.

He said he also hopes people will imagine their own hands as the ones in the illustration.

You can get the idea of whats being conveyed, but theres still enough room for you to inject yourself, Elliott said. Thats the power of symbolism and illustration.

A model carries a backpack from People for Urban Progress's new Ignitor line. Part of the sales from the line will go to a new PUP fellowship to support inclusivity in the Indianapolis design community.(Photo: People for Urban Progress)

The Ignitor backpacks are made from black pool coverings donated by a national pool company. Each backpack is made by hand at the PUP headquarters on the west side of Indianapolis, where employees unravel rolls of pool covering, cut them and stitch them into backpacks. Dabney said it takes a day and a half to cut one batch of 10 backpacks and a week to sew a single batch.

Dabney said the backpacks continue PUPs tradition of creating products from salvaged materials. The organizations first project in 2008 transformed 13 acres of Teflon-coated fiberglass from the demolished RCA Dome into wallets, purses and messenger bags. The PUP Stops project involved turning old Bush Stadium seats into IndyGo bus stop seating. Their Amtrak Collection included backpacks, bags, wallets and accessories made of leather from Amtrak train seats.

We need to see ourselves as citizens and not just consumers, Dabney said. And part of that is understanding the purpose of reuse and using design to fit the needs of our community.

Promotional materials picture a new backpack from People for Urban Progress's Ignitor line. Part of the sales from the line will go to a new PUP fellowship to support inclusivity in the Indianapolis design community.(Photo: People for Urban Progress)

The final piece of the Ignitor line is raising funds for an in-house design fellow from an underrepresented community to use the PUP platform and resources for their work. The PUP fellow will be tasked with creating a design project that benefits the Indianapolis community and incorporates the ideas of repurpose and reuse.

Dabney said she wants the fellowship to identify and uplift underrepresented designers and make Indianapolis more aware of their work. Eventually, she said she hopes the designers included around their table look like the community they serve.

Theres a difference between diversity and inclusion, she said. Diversity is inviting someone to the dance. Inclusion is asking someone to dance with you. We need to do both to ensure equity and inclusion at the table.

Ignitor T-shirts, which cost $28 and come in sizes XS and XXL, can be found on the PUP website and at Silver in the City at its stores on Massachusetts Avenue in downtown Indianapolis and on Main Street in Carmel. The backpacks, which cost $225 each, can be found on the website.

Contact Pulliam Fellow Christine Fernando at cfernando@gannett.com.

Read or Share this story: https://www.indystar.com/story/entertainment/arts/2020/08/31/people-for-urban-progress-indianapolis-launches-line-promoting-racial-unity/5646580002/

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This is more than a T-shirt. 'This is my way of protest.' - IndyStar

BEAVER CREEK Saying people want a doggone solution to the COVID-19 pandemic, Sen. Cory Gardner spoke to supporters at Beaver Creek on Friday on the first day of the 2020 Freedom Conference and Festival.

The conference is a 12th-annual event from the Steamboat Institute, but COVID-19 restrictions prevented the event from being held in Steamboat Springs this year. Beaver Creek was able to accommodate the group.

The widespread restrictions on social gatherings are in direct violation of (the First Amendment), and we believe that defending and exercising this right is at the core of what the Steamboat Institute stands for, wrote Jennifer Schubert-Akin, institute chairwoman, in a welcome letter to attendees.

In addition to SchubertAkins welcome packet, attendees were given copies of The Declaration of Independence, The Constitution of the United States, Trent Englands Why We Must Defend The Electoral College, and a Steamboat Institute pamphlet titled How Lockdowns Infringe on Civil Liberties, A Pocket Guide.

A COVID-19 panel discussion featured economic doctor Arthur Laffer, medical doctor Scott Atlas, and Gardner, who touted economic recovery legislation and advances in science, saying the country is close to receiving a COVID-19 vaccine.

Were gonna have a vaccine, said Gardner,who is polling behind Democratic challenger John Hickenlooper, Colorados former governor and presidential candidate, in his re-election campaign. Its going to be similar to a flu vaccine, where youre going to probably have to get it every year, and there will be different types of vaccines, and were going to get through this.

Atlas said he also believes the country is going to progress with the vaccine, but even if we didnt, we are going to be OK here, he said.

Atlas, who is a special advisor to President Trump, began the discussion by saying while states have begun reopening, significant limits to those reopenings remain, including travel warnings, quarantine requirements, reduced capacity on retail, bars that remain closed, reduced capacity at fitness centers, reduced capacity at restaurants, take-out only restaurants, and online-only and hybrid-attendance at schools.

The harms of continuing those lockdowns are enormous, Atlas said.

Citing data from the Centers for Disease Control and Prevention, Atlas also said the most recent analysis indicates that the infection fatality rate for COVID-19 patients under 70 years of age is 0.04%.

Which is less than or equal to seasonal influenza, he said.

In addition to their confidence in vaccine development, panel members expressed optimism in population immunity, medical community response and market recovery, even crediting Gov. Jared Polis for Colorados response.

I think your governor has done a phenomenal job on bringing this state back into process, Laffer said.

While Laffer had kind words for his host in Polis, more immediately in Beaver Creeks Gerald Ford Hall, where the Freedom Conference took place, he had less enthusiastic words for the buildings namesake, saying President Fords Whip Inflation Now program cost enormous lives and cost enormous wellbeing.

Laffer said like Fords program, the 2020 pandemic response in the U.S. was a result of politicians making decisions while panicked.

There were lots and lots of mistakes, Laffer said. They were not done deliberately, obviously.

Atlas said Trumps plan is aimed at saving even more lives while rolling back limitations to reopening and protecting high-risk populations.

That means highly detailed, real-time monitoring; a smarter, prioritized, very intensive testing strategy of nursing home staff and residents; pro-active warnings to high-risk elderly in regions of increased in-community infection; massive allocation of extra resources including point-of-care testing in all 14,500 nursing homes by mid-September and rapid mobilization of CDC strike teams where surge testing is needed, Atlas said.

We will continue to emphasize to the public the goal of protecting the high-risk group, including importantly adopting the highest standards of hygiene and social distancing, all the things weve already learned, when interacting with elderly friends and family members at risk, he added.

Addressing dozens of unmasked viewers in Gerald Ford Hall, some of them elderly, Atlas said some mask policies are reasonable, especially concerning those in high-risk groups.

Wear a mask if you cannot socially distance, particularly in certain settings, he said. When youre close by somebody, its reasonable. When youre walking into a nursing home and theres a very, very high-risk situation, OK, then you gotta be super, super cautious when youre near people, and you can not socially distance.

Moderator Hadley Heath Manning said a lot of risk assessment and risk taking during a pandemic is a very personal choice. Manning said she flew across the country to visit her grandparents during the pandemic.

My grandmother insisted that we come to her house, Manning said. She made me think of a passage from Esther in the Bible If I perish, I perish.

Laffer, who is 80, said he has also visited with his grandchildren and great-grandchildren during the pandemic.

Frankly, I love my grandchildren far more than I love myself, Laffer said. And I just dont want this economy shut down and have their futures put at risk because of someone wanting to save another 80-year-old like me.

Gardner said we have to save the elderly, because there would be no one left in the Senate otherwise.

I have a vested interested in my colleagues, to make sure they get this right, he said with a laugh.

More here:

Sen. Gardner touts vaccine progress, pandemic legislation at Steamboat Institute's Freedom Conference in Beaver Creek - Steamboat Pilot and Today

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The Georgetown Companies CEO Adam Flatto

Nearly 30 years ago, when Limited Brands founder Les Wexner decided the huge parcel of land he owned off of Interstate 270 in Columbus would make a better retail destination than a distribution center, his plans for a combination of shops, restaurants, hotels, and apartments made some eyes roll. Today, Easton Town Center serves as one of the worlds largest and most successful examples of mixed-use real estate. Wondering how Eastons fared during COVID-19, we talked to its developer, Adam Flatto, CEO of The Georgetown Companies.

Hows Easton operating at this stage of the crisis? Whats open and doing well and whats not? Are you going to lose many tenants that have entered Chapter 11?Weve been extremely well received by customers. Weve been drawing up to 75 percent of last years traffic and thats without the theaters being open. The fact that Easton is an outdoor project has helped us. You can spend some time here with much less risk than youd have at a traditional mall. Our tenants have largely taken a collaborative, creative approach and our management team has worked to evolve operations incredibly quickly to put health and safety first.

COVIDs been terribly harsh to commercial real estate. Theres been a 300% increase in loans and mortgages being assigned to workout specialists. Have you gone that route?Easton was able to leverage its long-term financial strength with all of its lenders, including CMBS, commercial banks, and insurance companies, to develop a special service arrangement that includes deferring interest payments for a number of months. We were not in a position where we were forced to do this. Ohio Governor Mike DeWine urged lenders to enter into agreements like this and we called our lenders and proposed it. They were eager to negotiate the arrangement and I think we were the first to do it here. This allows us to be more flexible and support the 250-plus restaurants and retailers that call Easton home.

Mall of America has missed three mortgage payments and entered into a forbearance agreement. CBL has worked out a restructuring and will use Chapter 11 to increase liquidity. Was Easton ever in danger of foreclosure?Easton was never in danger of foreclosure. There is a misperception out there that special servicing must mean that foreclosure is in the cards, and thats just not the case. In fact, the restructuring agreements we entered into were a proactive move on our part to allow our team to be more creative and flexible to each tenants current situation and needs. This way, our restaurants, retailers, and service providers have a more long-term strategy to remain active while we all weather the COVID-19 storm together.

Are there other large developments that have done this?Absolutely. Developers working with trusted lending partners to reach creative solutions that are in the best interest of all parties is not a new phenomenon. Its been a common practice in the real estate industry for decades and several prominent malls and developers have taken similar approaches.

Lets end with some positives. What are some things Easton has going on that youre really happy about? How do you feel youre positioned for the holiday season?Twenty-eight years ago, we and Les Wexner set a course for this project that was going to be different from enclosed malls. There was to be a strong entertainment and lifestyle emphasis. We had hotels and apartments. It was something that was unheard-of back then. Whats happening here now shows us what a great decision that was. Heading into December, we are all hands-on-deck to cultivate the innovative, safe, community events that the Columbus market has come to know and love at Easton.

Read more here:

5Qs for Adam Flatto on Easton Town Center's progress during the pandemic - Chain Store Age

John Eastman, head football coach at Troup High School, has been named as the Jacksonville Progress Coach of the Week.

Eastman, who has guided the Tigers to 17 wins in the past two seasons, led Troup to a 27-0 win over Alto in Alto on Friday night in what was the season opener for both squads.

Alto has proven to be especially tough to beat on their home turf through the years, and to shut out the Yellowjackets just doesn't happen very often, regardless of where the game is played.

By holding Alto scoreless, Troup managed to do something that had not been done in 17 years (Timpson last blanked Alto 25-0 on Nov. 7, 2003).

With just three starters back on the offensive side, some felt it would take the Tiger offense a game or two to get in sync.

That was not the case.

Tiger quarterback Trevor Padia, playing in his first game as a varsity starter, went 10-17 for 234 yards and two touchdowns through the air. He also was effective running the ball (14-91, two touchdowns).

Eastman and staff made a lot of wise personnel decisions to fill those eight holes on offense, putting the right young men in the spots that allowed them to be successful, and that is what coaching is all about.

Read more here:

Eastman named Progress Coach of the Week | Sports - Jacksonville Daily Progress

While the rare cancer landscape is growing, progress is happening thanks to patients advocating for their care.

Some diagnoses are straightforward; others can take months or even years to pinpoint. That is why it is crucial for patients who know that something is not right to continue to follow up with their care team or seek out specialists.

Our feature story describes the experience of a woman who was not satisfied with her doctors answers regarding her abdominal pain and bloating. After pushing on through many visits with health care professionals, including specialists, she eventually received a diagnosis of late-stage appendix cancer. That persistence likely saved her life, because the disease tends to not show many symptoms until it is advanced. Once signs appear, diagnosis and treatment are crucial.

Self-advocacy does not stop there. Patients with rare cancers or their parents or caregivers should seek out a medical team that specializes in treating their disease. Finding clinical trials and physicians who treat rare diseases can lead to monumental breakthroughs, such as the first Food and Drug Administration approval for children with neurofibromatosis type 1.

In this issue of CURE, we hear from the researchers who contributed to the life-changing approval for a therapy for this condition; traditionally, only the symptoms, not the disease itself, could be treated.

Major advances do not only rely on patients and researchers but also result from organizations teaming up to gain better patient outcomes. For example, the Cholangiocarcinoma Foundation worked with health technology companies to gather data and improve patients access to top-notch care.

Many key players are moving the field of cancer forward, especially among the rarer malignancies. In this special issue, we highlight some of these people and their work, but remember: It always starts with the patient.

Read more:

With Rare Cancers, Progress Starts With the Patients - Curetoday.com

Exterior work is progressing on1100 Avenue of the Americas, a 15-story office building at the corner of West 42nd Street and Sixth Avenue, directly across from Bryant Park. Brookfield Properties is the developer of the 386,190-square-foot structure, which is receiving an interior renovation and faade redesign by MdeAS Architects. As revealed in renderings released last fall, the new glass curtain wall will be much lighter and more transparent than the original reflective envelope. The property will contain357,940 square feet of commercial office space and 11,239 square feet of ground-floor retail area. Aecom Tishman is the general contractor.

Recent photos show the entirety of the southern elevation and most of the western elevation covered in scaffolding and black netting. All of the original curtain wall has been removed, exposing the steel superstructure. Metal clips are in place on the edges of the floor plates in preparation for the installation of the new faade. An exterior hoist is positioned on the uncovered northern face, and yellow insulation panels are wrapped around the mechanical extension above the roof parapet.

1100 Avenue of the Americas. Photo by Michael Young

1100 Avenue of the Americas. Photo by Michael Young

1100 Avenue of the Americas. Photo by Michael Young

1100 Avenue of the Americas. Photo by Michael Young

1100 Avenue of the Americas. Photo by Michael Young

The existing floor plates measure around 25,000 square feet apiece. The renovation also includes the addition of a new roof terrace that will provide occupants views of Bryant Park, the Empire State Building, and the surrounding Midtown skyline.

The completion date for 1100 Avenue of the Americas revamp was last reported for late 2020, as indicated on the construction board. However, sometime in early 2021 looks more likely.

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Renovation of 1100 Avenue of The Americas Making Progress in Midtown - New York YIMBY