Category Archives: Progress

TULSA, Okla. (KTUL) The Tulsa Housing Authority said it's making progress in tackling a lack of affordable housing for Tulsans who need it.

The agency said results from this year's Point In Time count showed that a lack of affordable housing was a leading cause in Tulsans experiencing homelessness.

"For the first time in Tulsa's history the number one reported cause of homelessness was the lack of affordable housing," said Vice President of Communications & Public Affairs for the Tulsa Housing Authority Ginny Hensley.

Hensley said the agency has been working to improve that problem around the city. Last year it purged its public housing waitlist for the first time since 2017.

The purge cleared over 13,000 names from the list and required citizens still interested to reapply. Hensley said the purge was ultimately beneficial to get the agency in touch with people who actually still needed the help.

"It just reduces the amount of time that it takes to get people in homes," said Hensley. "We had reached a point where the data was no longer valid."

Hensley said outdated contact information and people telling the agency that they no longer needed the assistance had previously made the process more tedious than it needed to be.

Hensley said the agency is still required to call or attempt to contact, anyone who applies for public housing.

"Since we purged that waitlist we now have over 9,000 folks just on the waitlist for public housing," said Hensley.

Hensley said the agency is also making strides on its Choice Neighborhoods project. NewsChannel 8 was invited out Thursday to witness the demolishment of the Comanche Park community center. It's part of the agency's Comanche Park community that also serves as a public housing option for Oklahomans in need.

The 36th Street North project will include about 550 mixed-income units in north Tulsa which the agency said is about halfway along from its 2025 expected completion.

"A $200 million improvement in affordable housing, mixed-income community here in north Tulsa," said Hensley Thursday when asked about the potential benefit.

The agency said residents of Comanche Park will have the first choice of housing units available when the project concludes, in hopes of helping expand and encourage prosperity within the community.

More:

Progress made in Tulsa's affordable housing crisis - KTUL

President of Ukraine Volodymyr Zelenskyy and Prime Minister of the United Kingdom Rishi Sunak on May 15, 2023

According to the president, Kyivs partners have pledged substantial future military aid packages.

Read also: Ukrainians submit nearly 3,000 applications for financial aid under the e-Restoration program

"As a result of these visits, Ukraine will receive more new and powerful weapons for the front, greater security for our people, and more political support," said Zelenskyy.

He outlined these new security commitments as follows:

France will provide a major military aid package, additional armored vehicles, and will help coordinate the work of Ukraines allies;

Italy will transfer additional air defense systems and assist in Ukraines post-war reconstruction;

Germany has pledged a $2.94 billion security assistance package, IRIS-T anti-air systems, and a EUR 11 billion long-term defense support program;

The UK will begin training Ukrainian pilots on modern Western military jets.

He added that the UK and Poland have already agreed to train Ukrainian pilots, suggesting that Kyiv is "actively moving" towards getting modern fighter jets from its international partners.

Read also: Long way to go before victory, says Zaluzhnyi

"So, the main results of these days are: new weapons for Ukraine, respect for Ukrainians, and our victory has become closer," the president concluded.

Were bringing the voice of Ukraine to the world. Support us with a one-time donation, or become a Patron!

Read the original article on The New Voice of Ukraine

See original here:

Zelenskyys Europe trip secures more military aid, makes progress on fighter jets - Yahoo News

Neuer is still targeting a July return date when Bayern begins preseason for the 2023/24 campaign.

Yann Sommer has now recorded two clean sheets from Bayern Munichs last three Bundesliga wins as theyre still on pace to win their eleventh straight Meisterschale so long as they dont drop points next weekend to RB Leipzig. Even with another Bundesliga title to add to the trophy cabinet in Munich, the season would largely be considered sub-par due to getting knocked out of both the DFB-Pokal and Champions League again far sooner than they wouldve liked.

The optics and timing around the managerial switch from Julian Nagelsmann to Thomas Tuchel placed increased scrutiny on Bayerns front office and board, but they have remained adamant in their backing of Tuchel moving forward. For what its worth, Tuchel inherited a squad made up predominantly of Nagelsmann signings, one of which was Sommer during the winter transfer window as an emergency replacement for Manuel Neuer. Now, reports suggest that Sommer could be on his way out of the club this summer, not wanting to fall behind Neuer in the pecking order in the keepers spot. Tuchel has maintained that Neuer will more than likely resume his role as the starting keeper when hes back healthy.

To add to it, both Tuchel and Bayerns sporting director recently expressed their delight with how well Neuers recovery has been going. The keeper is still aiming for a full return to action come the beginning of July when Bayern begins their preseason preparations for the 2023/24 season. Its sensational news and its great to see how Manu is rewarded for his work. We wont set any schedule. Not even with Lucas Hernndez - they are outstanding athletes. The attitude they have here at the training ground is extremely positive, Tuchel said on Neuers recovery, and likewise that of Lucas Hernandezs, who he is excited to have back in the squad, potentially before this season concludes (via @iMiaSanMia).

Photo by Sven Hoppe/picture alliance via Getty Images

After Bayerns 6-0 thrashing of Schalke 04, Brazzo was equally as excited as Tuchel to speak about Neuers fast-tracked recovery and eagerness to have him back in the squad. Theyre in regular communication with regards to his status, as well. We talk to each other every day.. Hes making a good impression. We are happy that he is on the right track. Theres still a bit to go, but its getting better and better every day, Brazzo explained.

Read more

Go here to read the rest:

Thomas Tuchel, Hasan Salihamidzic pleased with Manuel Neuers recovery progress at Bayern Munich - Bavarian Football Works

Work on West Wooster Street will continue through the summer. (Debbie Rogers | Sentinel-Tribune)

By Peter Kuebeck

[emailprotected]

Utilities work which has affected West Wooster Street since last year will continue this summer.

Theyre going to continue to do their work on the sewer, said Public Infrastructure Director Brian OConnell. They continue to make progress. Theyve got to get the sewer down to Church Street and then theyve got to come back and theres a little bit of work yet to do on Haskins Road.

There is also work involving a trunk sewer which goes north on Meeker Street and flows to the wastewater treatment plant.

So theyre going to finish up the sewer work, maybe late July, early August timeframe, OConnell said.

Afterward, there will be work to pave Wooster from Church Street west, and then paving on Haskins Road to north of Poe Road and to the city limits.

OConnell said that previous work in the area on a water line is completed, and the sewer work currently being undertaken involves consolidating multiple older sewers into one new, larger sewer.

It will simplify our operations and maintenance in the area, well have a brand new sewer to service the entire area and just be easier for us to maintain overall, he said.

With the new water and sewer lines, OConnell said, there shouldnt be issues with leaking pipes or old clay tiles falling apart.

Were trying to solve a few issues with this project, he said.

OConnell noted that the city has delayed some road work projects on Pearl Street and the Wallace Avenue area due to the West Wooster project, so as not to cause any additional issues for drivers.

He also said that other neighborhood paving projects wont be an issue.

The other paving projects, I think theyre going to be more in the residential neighborhoods and those are more isolated to those specific neighborhoods, he said.

With the roundabout under construction currently at Campbell Hill Road, Alumni Drive and East Wooster Street, OConnell said that while people traveling across town would be impacted by both projects, they arent impacting one another.

Theyre two different contractors, two different projects. Campbell Hill is far enough away from Church Street that they dont really impact each other from a disruption standpoint, from my standpoint at least, he said. But overall the two projects are fairly well separated that they dont seem to be causing an impact on each other or issues with traffic heading one way or the other.

I think when its done, it will be a big improvement for just traffic flow and navigating the area in general, OConnell said of the roundabout.

The $3.2 million West Wooster project was included in the 2022 budget and is being paid for from the citys water and sewer capital improvement funds.

Read this article:

'Progress' on West Wooster, but work will continue through summer ... - Sentinel-Tribune

SEYMOUR (KFDX/KJTL) One of the first houses ever built in Seymour is still in the works of getting some much-needed repairs after a non-profit stepped up to help.

It started for Pastor Jesse Villanueva and his family three years ago in Munday. From there, he said he felt the calling to help more people in September when it comes to home repairs.

Thats when Villanueva and his family received a call about one of the oldest houses in Seymour. He said when he visited the house, it was in need of a new porch, roof repair, and much more.

Since starting in September, donations have led to a new deck being installed, and parts of the roof have new shingles.

This is only one of several projects he and his family have at the moment. My Rock Ministry helps those who are disabled, seniors, low to fixed-income families, and more.

We try hard to come forward and come out and get involved with the communities, get involved with the people. We pray with them, we cry with them and were trying to build the bridge to save their life, and a lot of times, its just a small repair that will re-establish their relationship inside the entire family or re-establishment with God, Villanueva said.

All the work done by Villanueva and his family is through volunteers, donations, and community support, all which are always needed.

Donations can be made by contacting Villanueva or visiting the My Rock Ministrys Facebook page.

Villanueva ask to let them know which specific project youd like to donate to so he knows how to use the money, such as donating to the project in Seymour, as he currently has about 200 around Texoma and beyond.

See more here:

My Rock Ministry progress on home repairs for one of oldest houses in Seymour - KFDX - Texomashomepage.com

A new report from the Chesapeake Bay Program says states need to flip the script in order to achieve pollution reduction goals for the Chesapeake Bay.

The 133-page report released by the programs Scientific and Technical Advisory Committee offers a range of findings about why progress toward those goals has been slow and why water quality improvements are proving more challenging than expected.

Among those findings are that pollution reductions from farmers have been insufficient, plans need to better take into account climate change and different habitats within the watershed with unique characteristics, and future conditions will impact the Bay differently in years to come.

Under the Chesapeake Bay Agreement, Virginia, Maryland, Pennsylvania, Delaware, New York, West Virginia and the District of Columbia agreed to meet specific goals to reduce pollution from entering the 64,000-square-mile watershed. Late last year, the Environmental Protection Agency acknowledged that the 2025 goals are not likely to be met.

While pollution reductions have resulted from upgrades to wastewater treatment plants, most of the remaining reductions must come from so-called nonpoint sources, or those that are spread widely over geographic areas. Nonpoint sources include runoff from agricultural fields, urban areas and impervious surfaces, explained report co-editor Kurt Stephenson, a professor of agricultural and applied economics at Virginia Tech.

It is the major challenge confronting water quality management now and into the future, Stephenson said. Three-quarters of the [pollution] loads entering the Chesapeake Bay come from nonpoint sources. The largest majority is from agriculture.

The report finds that existing efforts to reduce pollution from the agricultural sector through the use of best management practices have not been effective. According to the report, tens of millions of pounds of nitrogen reductions are needed to achieve the Bay water quality goals, but since 2010 best management practices have only produced 3 million pounds a year of nonpoint source reductions.

The extensive history of nonpoint policy illustrates the limits of relying on voluntary actions, the report states. New and refined requirements may be necessary to achieve substantial progress in reducing nonpoint source loads.

Virginia has an agricultural cost-share program to ease the financial burdens placed on farmers for installing best management practices. That program recently received record levels of funding from the General Assembly, which also recently extended the deadline for farmers to voluntarily install BMPs before they are required to.

Stephenson said that instead of instituting policies that incentivize farmers to implement certain practices, states could reward farmers for achieving greater pollution reductions.

Practices like planting riparian buffers are highly cost-effective from a public standpoint in terms of getting reductions per dollar, said Stephenson. They can be highly effective. But nobody has any incentives to adopt things that have high upfront costs and no personal benefit.

The report also finds nutrient reductions havent achieved the water quality improvements expected.

One reason for that is that tipping points, or periods when small changes yield big responses, havent been hit yet, explained Denice Wardrop, report co-editor, executive director of the Chesapeake Research Consortium and a professor of geography and ecology at Penn State University. Rising temperatures linked to climate change that offset roughly 6% to 34% of the nitrogen reductions that have occurred could also play a role.

The Bay of the future is not the Bay of the past, and we have no historical precedent and model to go off of, said Wardrop.

Improvements in resources like fish and wildlife populations can be achieved through additional management actions that dont need to apply across all habitats, the report notes. Instead, states might embrace different reduction goals for different habitats or incorporate the benefits of restored wetlands or living shorelines into load reduction calculations.

Uncertainties lie ahead for the Bay, the report authors note, given climate change, population growth and economic development.

Refining restoration goals over time should be considered as knowledge evolves about what future conditions are possible, what local communities and the partnership at-large see as priorities, and what is required to attain those possible futures, the report says. Uncertainty is inherent in each of these.

GET THE MORNING HEADLINES DELIVERED TO YOUR INBOX

SUBSCRIBE

Continued here:

Report details why progress to clean up the Chesapeake Bay has ... - Virginia Mercury

(RNS) Modernity is crumbling.

You can see it in the news. Rather than hearing about supposedly sophisticated, enlightened people, every day there are stories that seem to have been ripped from history pages about ancient barbarians and medieval vandals.

Halls of government are increasingly characterized by political theater more than rational, civil debate. We continue to grapple with the multiple long-term effects of a pandemic that is reminiscent of the Black Death. A former president, a leading candidate for the next presidential election, has been found liable in civil court for sexual battery.

Meanwhile, hundreds of citizens are being arrested, tried and convicted for violent acts undertaken to thwart democracy. Innocent people including children are being shot by private citizens simply for playing, sleeping, going to school or trying to pick up younger siblings at the wrong house. We drag kids to adult entertainment. The nations most-watched political commentator apparently doesnt believe a word he says.

So much for human progress. Whatever belief one might have held in the possibility of this idea, such a belief seems less tenable with each passing day.

The notion of progress is a modern one. By modern, I mean the modern age that was birthed by the Enlightenment and the very real advances it made in human knowledge. What made the modern age modern was the scientific revolution, a dramatic shift in the foundation of what we called knowledge. Once rooted in religion and myth, truth would now be rooted in reason and science.

Modernity, however, still carries a myth of its own.

The myth encompasses many things, but perhaps can be boiled down to a belief in the idea that our world and we can be governed by reason alone and that because of our reliance on reason our societies (and we) are more advanced than were people and civilizations of ancient times.

The myth of the modern, as a friend of mine observed the other day, is slowly unraveling.

Yes, civilizations rise and fall. Along the way, they have peaks and valleys.

People shelter in the House gallery as protesters try to break into the House chamber at the U.S. Capitol on Jan. 6, 2021, in Washington. (AP Photo/Andrew Harnik)

Those of us whove been around for half a century or more can attest to an overwhelming sense that 21st century American civilization has entered a valley. Our recent days are defined by cruelty, lawlessness, the shattering of norms and traditional boundaries, and an eagerness to annihilate truth and trust in institutions, Peter Wehner observed in a recent essay at The Atlantic.

The confidence in human potential, accomplishments and mastery over the natural world (one might more properly term such confidence pride) that the modern age cultivated is misplaced. It is all part of the myth.

Having given too much weight to this myth myself, I am at once chastened and cheered to see it unraveling. But recognizing it as a myth in order to see ourselves and the world we have made more clearly is perhaps our best hope. Science, technology and knowledge march forward, all based in reason. But the human condition remains unchanged. If we thought we are doing things better than our parents, our grandparents or our ancestors from long ago, we were wrong.

Yes, we are doing better on some things. Women can vote now! We dont auction fellow human beings in the town square! We sneeze into our elbows instead of our hands! But even in these advances we lurch forward by emotion, acting out in partisan enmity, with little optimism about human reason. We rarely show ourselves to be governed by our rational powers.

Ive spent the past couple of years researching and writing about some of the striking parallels between the 19th and the 21st centuries for a forthcoming book. As is our own day, the Victorian age, too, was convinced of its potential for both individual and social progress. Yet, in the midst of these hopes, wiser artists and philosophers offered prescient warnings.

One fitting warning for us can be found in Fyodor Dostoevskys 1864 novella, Notes From Underground.

The storys narrator, an unnamed recluse, offers personal confessions about his past life and cynical analysis about his present society, a society taken with its own sense of progress and improvement, symbolized by the Crystal Palace, a real-life British monument built to showcase the best inventions from around the world.

Amid such breathtaking human accomplishments, the narrator imagines a gentleman with an ignoble, or rather with a reactionary and ironical, countenance who rises to say, hadnt we better kick over the whole show and scatter rationalism to the winds, simply to send these logarithms to the devil, and to enable us to live once more at our own sweet foolish will!

Dostoevskys Underground Man concludes, he would be sure to find followerssuch is the nature of man.

Indeed, in the midst of Americas general prosperity, not just one ignoble gentleman, but legions of people seem gleefully, with arms akimbo, to be kicking over the whole show.

Whether such destructiveness is for the purpose of fame, power, wealth (or all three) it is hard to tell. Watching certain social media influencers gain followers by the millions with flame-throwing posts, I cant help but wonder if the purpose is merely, and more basely, to fulfill some sadistic delight in causing others to suffer.

The Underground Man can relate to this too:

They say that Cleopatra (excuse an instance from Roman history) was fond of sticking gold pins into her slave-girls breasts and derived gratification from their screams and writhings. You will say that that was in the comparatively barbarous times; that these are barbarous times too, because also, comparatively speaking, pins are stuck in even now; that though man has now learned to see more clearly than in barbarous ages, he is still far from having learnt to act as reason and science would dictate.

The halcyon days of modern progress and prosperity lead to boredom It is boredom sets one sticking golden pins into people, he says which leads him to conclude, I dare say people will be thankful for the gold pins

What is the entire outrage industry but the fruit of a bored people, a people who know not how to find satisfaction in the quietness of a book, the work of the hands, or the love of family and friends?

What is rage farming the enflaming of passions that overtake reason for the sake of clicks and personal profit but proof of the myth of the modern?

The myth of the modern is that the truth that will set us free is a truth of our own making. Perhaps the unraveling of this myth will lead us out of our current valley.

View original post here:

Human progress, the myth of the modern age, is increasingly in doubt - Religion News Service

heart-1 Clinical Trial of VERVE-101 Ongoing with Initial Data Expected in the Second Half of 2023

VERVE-102 Named Second PCSK9-Targeting Program, Leveraging Novel GalNAc-LNP Delivery with Clinical Trial Initiation Expected in the First Half of 2024

VERVE-201 Targeting ANGPTL3 Progressing with Clinical Trial Initiation Expected in the Second Half of 2024

Well-capitalized with $508.7 Million Supporting Runway into the Second Half of 2025

BOSTON, May 15, 2023 (GLOBE NEWSWIRE) -- Verve Therapeutics, Inc., a clinical-stage biotechnology company pioneering a new approach to the care of cardiovascular disease with single-course gene editing medicines, today reported pipeline progress and financial results for the first quarter of 2023.

The focus at Verve is to develop life-changing medicines for people with cardiovascular disease, said Sekar Kathiresan, M.D., co-founder and chief executive officer of Verve. As leaders in the advancement of in vivo gene editing treatments to address cardiovascular disease, we believe that we are well positioned to achieve that goal. We now have several novel gene editing programs progressing, with our lead program being evaluated in the heart-1 clinical trial, and two additional programs expected to advance into the clinic next year. We have developed potentially best-in-class proprietary liver delivery technologies, established strategic collaborations with industry leaders, and have a financial position that we expect will fuel a multi-year operating runway. I am excited about our future and the opportunity to shift the treatment paradigm for the millions of people affected by ASCVD.

Cardiovascular disease remains the leading cause of death in the world and care currently relies on a chronic treatment model of oral and injectable therapies administered over decades, imposing a heavy treatment burden on patients, providers and the healthcare system. About 50% of patients with atherosclerotic cardiovascular disease (ASCVD) in the U.S. are not currently on statin therapy1, todays standard-of-care aimed at lowering disease-driving low-density lipoprotein cholesterol (LDL-C). Familial hypercholesterolemia (FH), the lead indication for Verves gene editing programs, is a morbid genetic cardiovascular disease marked by high levels of circulating LDL-C and ASCVD at an early age. More than 95% of FH patients worldwide are not at treatment goal for LDL-C2, further highlighting the critical need for treatments that meaningfully and durably reduce blood levels of LDL-C.

Verve is developing a pipeline of gene editing programs targeting the three lipoprotein pathways that drive ASCVD: LDL, triglyceride-rich lipoproteins (TRL) and lipoprotein(a) (Lp(a)). The companys pipeline is led by its clinical-stage candidate, VERVE-101 targeting the PCSK9 gene, followed by two preclinical-stage programs, VERVE-102 also targeting PCSK9 and VERVE-201 targeting ANGPTL3.

Andrew Bellinger, M.D., Ph.D., chief scientific officer and chief medical officer of Verve stated, We are deeply committed to solving FH by targeting PCSK9 and ANGPTL3. When we started, we took what was a new base editing technology and an in-licensed lipid nanoparticle (LNP) and created VERVE-101. Since then, we have invented our own GalNAc-LNP delivery technology that enters liver cells through the use of either of two receptors the LDL receptor (LDLR) or asialoglycoprotein receptor (ASGPR) and with potential advantages of increased potency and greater tissue specificity. We have applied our GalNAc-LNP to develop an ANGPTL3 gene editor, VERVE-201, and created a second PCSK9 gene editor, VERVE-102, providing another opportunity to address this attractive target and the unmet needs of patients with FH. With this second program targeting PCSK9, we are enhancing optionality within our portfolio and maximizing our opportunity to bring the best product forward for patients. With VERVE-101 in the clinic, and VERVE-102 and VERVE-201 expected to enter the clinic next year, we look forward to advancing three product candidates that have the potential to disrupt the current chronic care model for ASCVD.

________________________1 Nelson AJ et al., J Am Coll Card. 2022;79(18):180213.2 EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC). Lancet. 2021;398(10312):1713-1725.

VERVE-101 Progressing in heart-1 Clinical Trial

VERVE-102 Named as Second PCSK9 Product Candidate

VERVE-201 On-Track for Clinical Initiation in 2024

Upcoming EventsVerve plans to participate in the following events in the second quarter of 2023:

First Quarter 2023 Financial Results

About heart-1heart-1 is an open-label Phase 1b clinical trial in patients with heterozygous familial hypercholesterolemia (HeFH) who have established atherosclerotic cardiovascular disease (ASCVD) to evaluate the safety and tolerability of VERVE-101 administration, with additional analyses for pharmacokinetics and reductions in blood PCSK9 protein and low-density lipoprotein cholesterol (LDL-C). Initial clinical data from the dose escalation portion of the heart-1 clinical trial including safety parameters, blood PCSK9 level, and blood LDL-C level are expected in the second half of 2023. For more information, please visit clinicaltrials.gov.

About Verve Therapeutics Verve Therapeutics, Inc. (Nasdaq: VERV) is a clinical-stage genetic medicines company pioneering a new approach to the care of cardiovascular disease, potentially transforming treatment from chronic management to single-course gene editing medicines. The companys initial three programs VERVE-101, VERVE-102, and VERVE-201 target genes that have been extensively validated as targets for lowering low-density lipoprotein cholesterol (LDL-C), a root cause of cardiovascular disease, in order to durably reduce blood LDL-C levels. VERVE-101 and VERVE-102 are designed to permanently turn off the PCSK9 gene in the liver and are being developed initially for heterozygous familial hypercholesterolemia (HeFH) and ultimately to treat atherosclerotic cardiovascular disease (ASCVD) patients not at goal on oral therapy. VERVE-201 is designed to permanently turn off the ANGPTL3 gene in the liver and is initially being developed for homozygous familial hypercholesterolemia (HoFH) and ultimately to treat patients with refractory hypercholesterolemia. For more information, please visit http://www.VerveTx.com.

Forward Looking Statements This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 that involve substantial risks and uncertainties, including statements regarding the companys expectations regarding communications related to the clinical hold on the IND for VERVE-101; the companys ability to enroll patients in its ongoing heart-1 trial; the timing and availability of clinical data from its heart-1 trial; the expected timing of initiating clinical trials of VERVE-102 and VERVE-201; its research and development plans; the potential advantages and therapeutic potential of the companys programs, including VERVE-101, VERVE-102, and VERVE-201; and the period over which the company believes that its existing, cash, cash equivalents and marketable securities will be sufficient to fund its operating expenses. All statements, other than statements of historical facts, contained in this press release, including statements regarding the companys strategy, future operations, future financial position, prospects, plans and objectives of management, are forward-looking statements. The words anticipate, believe, continue, could, estimate, expect, intend, may, plan, potential, predict, project, should, target, will, would and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Any forward-looking statements are based on managements current expectations of future events and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in, or implied by, such forward-looking statements. These risks and uncertainties include, but are not limited to, risks associated with the companys limited operating history; the timing of and the companys ability to submit applications for, its product candidates; advance its product candidates in clinical trials; initiate, enroll and complete its ongoing and future clinical trials on the timeline expected or at all; correctly estimate the potential patient population and/or market for the companys product candidates; replicate in clinical trials positive results found in preclinical studies and/or earlier-stage clinical trials of VERVE-101, VERVE-102, and VERVE-201; advance the development of its product candidates under the timelines it anticipates in current and future clinical trials; obtain, maintain or protect intellectual property rights related to its product candidates; manage expenses; and raise the substantial additional capital needed to achieve its business objectives. For a discussion of other risks and uncertainties, and other important factors, any of which could cause the companys actual results to differ from those contained in the forward-looking statements, see the Risk Factors section, as well as discussions of potential risks, uncertainties and other important factors, in the companys most recent filings with the Securities and Exchange Commission and in other filings that the company makes with the Securities and Exchange Commission in the future. In addition, the forward-looking statements included in this press release represent the companys views as of the date hereof and should not be relied upon as representing the companys views as of any date subsequent to the date hereof. The company anticipates that subsequent events and developments will cause the companys views to change. However, while the company may elect to update these forward-looking statements at some point in the future, the company specifically disclaims any obligation to do so.

Investor ContactJen RobinsonVerve Therapeutics, Inc.jrobinson@vervetx.com

Media ContactAshlea Kosikowski 1ABashlea@1abmedia.com

Continue reading here:

Verve Therapeutics Announces Pipeline Progress and Expansion ... - GlobeNewswire

Department of Environmental Conservation Commissioner Basil Seggos said,"DEC is proud of the significant progress underway to help achieve Governor Hochul's historic commitment to the people of Mount Vernon. Working together in partnership with Mayor Patterson-Howard, County Executive Latimer, and our sister agencies, DEC is working to address decades of inequity and injustice by helping property owners meet their most basic needs with effective clean water investments that will transform this community."

Environmental Facilities Corporation President and CEO Maureen A. Coleman said,"EFC is excited to celebrate a year of continuous communication and cooperation among the City of Mount Vernon, County of Westchester and our four partner agencies to help empower Mount Vernon by providing the funding,resourcesand technical assistance necessary for the city to begin making immediate fixes to critical infrastructure. From planning and design to construction, EFC is committed to working shoulder-to-shoulder with Mayor Patterson-Howard and Public Works Commissioner Bush to help transform the city's crumbling infrastructure into a resilient system that residents deserve. The success of this partnership reflects Governor Hochul's commitment to Mayor Patterson-Howard and the residents of Mount Vernon."

Homes and Community Renewal CommissionerRuthAnneVisnauskas said, When Governor Hochul called us to action in Mount Vernon, we moved quickly to complement the State's historic investment with direct support to the residents most impacted by the water and sewer crisis. Thanks to the partnership with our Federal, State, and City partners, we are providing dozens of families with the peace of mind that comes from a safe and healthy home."

Department of Health Acting Health Commissioner Dr. James McDonald said, "DOH is thrilled to see that the collaboration between the City of Mount Vernon, the County of Westchester, and all partnering agencies has led to the start of construction on the water infrastructure, and the beginning of long-overdue improvements to the health of these New Yorkers. The Department thanks Governor Hochul for her enduring commitment to safe drinking water for Mount Vernon residents and all New Yorkers now and for years to come."

Chief Counsel at the Natural Resources Defense Council Mitch Bernard said,"For decades, residents of Mount Vernon, a majority-Black community, have been dealing with crumbling pipes and flooded basements with little recourse. Finally, they're getting some relief. With the completion of these wastewater infrastructure projects, the community will serve as a model for infrastructure agreements across the country to show that collaboration with state and local government can make things happen."

New York Assemblyman J. Gary Pretlow said,On behalf of the residents of Mount Vernon, I wanted to thank Governor Kathy Hochul for her leadership and expediency in addressing the citys sewage and water problem. The rebuilding of Mount Vernons infrastructure is the states commitment to sanitation and justice for all. This unprecedented collaboration between the state of New York, the County of Westchester, and the city of Mount Vernon is truly what good government looks like and stands for.

New York's Commitment to Clean Water

New York continues to increase its investments in clean water infrastructure. The 2023-24 Enacted budget included an additional $500 million in clean water funding as proposed by Governor Hochul, bringing New York's total clean water infrastructure investment to $5 billion since 2017. To leverage these investments and ensure ongoing coordination with local governments, the Governor proposed the creation of Community Assistance Teams to provide proactive outreach to small, rural, and disadvantaged communities to help them access financial assistance to address their clean water infrastructure needs. The initiative was recently launched and outreach meetings are underway. Any community that needs help with their water infrastructure needs is encouraged to contact EFC atefc.ny.gov/CAT.

In addition, voters approved the $4.2 billion Clean Water, Clean Air, and Green Jobs Environmental Bond Act in November 2022, advancing additional, historic levels of funding to update aging water infrastructure and protect water quality, strengthen communities' ability to withstand severe storms and flooding, reduce air pollution and lower climate-altering emissions, restore habitats, preserve outdoor spaces and local farms, and ensure equity by investing at least 35 percent, with a goal of 40 percent, of resources in disadvantaged communities.During Earth Week, Governor Hochul announced the first availability of Bond Act funding that, when combined with existing state funding sources, totals $425million being made available instate water grant funding.Applications are duebyJuly 28 and more information can be found atefc.ny.gov/wiia.

Read the original here:

Governor Hochul Celebrates Year of Progress Addressing ... - ny.gov

While the U.S. Securities and Exchange Commission (SEC) continues to rain enforcement fire onto the crypto industry, Krakens chief legal officer, Marco Santori, says a specific legal doctrine could undermine the regulators authority.

The so-called major questions doctrine a point of U.S. administrative law that suggests federal agencies shouldnt step in front of Congress to engage on points of major economic significance has been cited by Coinbase (COIN) in its preemptive defense of a pending SEC action, and Santori thinks its especially relevant as lawmakers start work on crypto oversight.

The fact that Congress is taking this up, and you have representatives on both sides of the aisle two committees having a historic joint hearing on it these are all indicators that there is in fact a major question, Santori said in an interview. A court might look at what Congress is doing and say that the agency is getting ahead of its mandate from Congress, that this is a major question that ought to be decided by Congress.

The top lawyer for Kraken, which itself had settled a major recent SEC accusation that its U.S. staking services amounted to an offering of unregistered securities, said the SEC and its sister agency, the Commodity Futures Trading Commission (CFTC), will have to bear in mind that doctrine, based in U.S. Supreme Court rulings.

The agencies have to decide for themselves whether this is a major question, said Santori, who was among the witnesses at this weeks joint hearing of the House Financial Services Committee and the House Agriculture Committee.

Santori said he was heartened that most lawmakers from both parties seemed to think legislation was in order for crypto oversight, though he acknowledged that the uncertainty of the Senates view leaves some question about its potential.

Continued here:

Krakens Top Lawyer Says Signs of Progress in U.S. Congress Put SEC in Legal Bind - CoinDesk