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Category Archives: Nootropics

The 10 Best Nootropic Supplements to Boost Brain Power – Healthline

Posted: February 5, 2023 at 10:59 am

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Nootropics are natural supplements or drugs that have a beneficial effect on brain function in healthy people.

Many of these can boost memory, motivation, creativity, alertness and general cognitive function. Nootropics may also reduce age-related declines in brain function.

Here are the 10 best nootropic supplements to boost your brain function.

Fish oil supplements are a rich source of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), two types of omega-3 fatty acids.

These fatty acids have been linked with many health benefits, including improved brain health (1).

DHA plays a vital role in maintaining the structure and function of your brain. In fact, it accounts for around 25% of the total fat, and 90% of the omega-3 fat, found in your brain cells (2, 3).

The other omega-3 fatty acid in fish oil, EPA, has anti-inflammatory effects that may protect the brain against damage and aging (4).

Taking DHA supplements has been linked with improved thinking skills, memory and reaction times in healthy people who have low DHA intakes. It has also benefitted people experiencing a mild decline in brain function (5, 6, 7).

Unlike DHA, EPA isnt always linked with improved brain function. However, in people with depression, it has been associated with benefits like improved mood (8, 9, 10, 11, 12).

Taking fish oil, which contains both these fats, has been shown to help reduce the decline in brain function associated with aging (13, 14, 15, 16, 17).

However, evidence for fish oils preservative effects on brain health is mixed (18, 19).

Overall, the best way to get the recommended amount of omega-3 fatty acids is by eating two portions of oily fish per week (20).

If you cant manage this, then taking a supplement could be beneficial. You can find many supplements online.

More research is required to find out how much and what ratios of EPA and DHA are beneficial. But taking 1 gram per day of combined DHA and EPA is generally recommended to maintain brain health (21).

If you dont eat the recommended amount of oily fish, consider taking a fish oil supplement to help promote good brain health and healthy brain aging.

Resveratrol is an antioxidant that occurs naturally in the skin of purple and red fruits like grapes, raspberries and blueberries. Its also found in red wine, chocolate and peanuts.

Its been suggested that taking resveratrol supplements could prevent the deterioration of the hippocampus, an important part of the brain associated with memory (22).

If this is true, this treatment could slow down the decline in brain function you experience as you get older (23).

Animal studies have also shown that resveratrol can improve memory and brain function (24, 25).

Additionally, one study on a small group of healthy older adults found that taking 200 mg of resveratrol per day for 26 weeks improved memory (26).

However, there currently arent enough human studies to be sure of resveratrols effects (27).

If youre interested in trying it, you can find supplements in stores and online.

In animals, resveratrol supplements have been shown to improve memory and brain function. Its not yet clear if the treatment has the same effects in people.

Creatine is a natural substance that plays an important role in energy metabolism. Its found naturally in the body, mostly in muscles and in smaller amounts in the brain.

Although its a popular supplement, you can find it in some foods, namely animal products like meat, fish and eggs.

Interestingly, creatine supplements can improve memory and thinking skills in people who dont eat meat (61).

Caffeine is a natural stimulant most commonly found in tea, coffee and dark chocolate.

Although its possible to take it as a supplement, there isnt really any need when you can get it from these sources.

It works by stimulating the brain and central nervous system, making you feel less tired and more alert (28).

In fact, studies have shown that caffeine can make you feel more energized and improve your memory, reaction times and general brain function (29, 30, 31).

The amount of caffeine in one cup of coffee varies, but generally its 50400 mg.

For most people, single doses of around 200400 mg per day are generally considered safe and are enough to benefit health (32, 33, 34).

However, taking too much caffeine can be counterproductive and has been linked with side effects such as anxiety, nausea and trouble sleeping.

Caffeine is a natural stimulant that can improve your brain function and make you feel more energized and alert.

Phosphatidylserine is a type of fat compound called a phospholipid, which can be found in your brain (35, 36).

Its been suggested that taking phosphatidylserine supplements could be helpful for preserving brain health (37).

You can easily buy these supplements online.

Studies have shown that taking 100 mg of phosphatidylserine three times per day could help reduce age-related decline in brain function (38, 39, 40, 41).

Additionally, healthy people who take phosphatidylserine supplements of up to 400 mg per day have been shown to have improved thinking skills and memory (42, 43).

However, larger studies need to be carried out before its effects on brain function can be fully understood.

Phosphatidylserine supplements could improve your thinking skills and memory. They could also help combat the decline in brain function as you age. However, further study is needed.

Acetyl-L-carnitine is an amino acid produced naturally in your body. It plays an important role in your metabolism, particularly in energy production.

Taking acetyl-L-carnitine supplements has been claimed to make you feel more alert, improve memory and slow down age-related memory loss (44).

These supplements can be found in vitamin stores or online.

Some animal studies have shown that acetyl-L-carnitine supplements can prevent age-related decline in brain function and increase learning capacity (45, 46).

In humans, studies have found that it may be a useful supplement for slowing the decline in brain function due to age. It may also be useful for improving brain function in people with mild dementia or Alzheimers (47, 48, 49, 50, 51, 52).

However, there is no research to show it has a beneficial effect in otherwise healthy people who arent suffering from a loss of brain function.

Acetyl-L-carnitine could be helpful for treating a loss of brain function in the elderly and people with mental disorders such as dementia or Alzheimers. Its effects in healthy people are unknown.

Ginkgo biloba is an herbal supplement derived from the Ginkgo biloba tree. Its an incredibly popular supplement that many people take to boost their brain power, and its available in stores and online.

Its thought to work by increasing blood flow to the brain and is claimed to improve brain functions like focus and memory (53).

Despite the widespread use of ginkgo biloba, results from studies investigating its effects have been mixed.

Some studies have found that taking ginkgo biloba supplements can help reduce age-related decline in brain function (54, 55, 56).

One study in healthy middle-aged people found that taking ginkgo biloba supplements helped improve memory and thinking skills (57, 58).

However, not all studies have found these benefits (59, 60).

Ginkgo biloba may help improve your short-term memory and thinking skills. It may also protect you from age-related decline in brain function. However, results are inconsistent.

Bacopa monnieri is a medicine made from the herb Bacopa monnieri. Its used in traditional medicine practices like Ayurveda for improving brain function.

Its been shown to improve thinking skills and memory, both in healthy people and in elderly people suffering from a decline in brain function (64, 65, 66, 67, 68, 69).

However, its worth noting that only repeated use of Bacopa monnieri has been shown to have this effect. People generally take about 300 mg per day and it may take around four to six weeks for you to notice any results.

Studies of Bacopa monnieri also show that it may occasionally cause diarrhea and an upset stomach. Because of this, many people recommend taking this supplement with food (70).

Bacopa monnieri has been shown to improve memory and thinking skills in healthy people and in those with a decline in brain function.

Rhodiola rosea is a supplement derived from the herb Rhodiola rosea, which is often used in Chinese medicine to promote well-being and healthy brain function.

Its thought to help improve mental processing by reducing fatigue (71).

People taking Rhodiola rosea have been shown to benefit from a decrease in fatigue and improvement in their brain function (72, 73, 74).

However, results have been mixed (75).

A recent review by the European Food Safety Authority (EFSA) concluded that more research is required before scientists can know if Rhodiola rosea can reduce tiredness and boost brain function (76).

Rhodiola rosea may help improve thinking skills by reducing fatigue. However, more research is needed before scientists can be certain of its effects.

S-Adenosyl methionine (SAMe) is a substance that occurs naturally in your body. Its used in chemical reactions to make and break down important compounds like proteins, fats and hormones.

It may be useful for enhancing the effects of some antidepressants and reducing the decline in brain function seen in people who have depression (77, 78, 79).

One study found that adding SAMe to the antidepressant prescription of people who had previously not responded to therapy improved their chances of remission by around 14% (80).

More recently, a study found that, in some instances, SAMe may be as effective as some types of antidepressant medications (81).

However, there is no evidence that this supplement benefits people who dont have depression.

SAMe could be useful for improving brain function in people with depression. There is no evidence it has this effect in healthy people.

Some of these supplements show real promise for improving and protecting brain health.

However, note that many brain-boosting supplements are only effective for people who have a mental condition or are deficient in the supplemented nutrient.

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8 Natural Nootropics To Improve Intelligence, Memory, And… – Biostrap

Posted: December 28, 2022 at 10:07 pm

What do caffeine, lions mane mushroom, and green tea have in common?

Theyre all sources of natural nootropics, or cognitive enhancers, used for brain health. While they may be new to many of us, nootropics have been used in both Chinese medicine and Ayurvedic healing for thousands of years.

Whether its boosting brain power before a big test or warding off memory loss in old age, people use nootropics for an array of personal and professional reasons. Regardless of what people use nootropics for, everyones looking at the same goal: to get more done and become more efficient in a shorter amount of time.

This demand for productivity has increased sales of both natural and synthetic nootropics across the globe. And in a market thats poised to reach $6.29 billion by 2028, according to Verified Market Research, you might just be wondering what nootropics can do for you. Heres what you need to know about naturally-sourced nootropics that can speed up your smarts.

Nootropics are any compounds, supplements, or drugs designed to improve cognitive function. Theyre used by people all over the world to improve intelligence, creativity, and motivation. In addition to supercharging productivity, nootropics can make you smarter and less stressed, holistic health practitioner Shari Auth told The Thirty.

Nootropics offer a range of cognitive benefits, including faster reaction time, increased alertness, improved memory, and decreased mental fatigue and fog. Some nootropics are also adaptogenic, meaning they help your body manage stress, Auth added.

Since there are so many medicines, plants, and substances that offer these benefits, there remains a debate about what is and isnt a nootropic. Psychologist and chemist Dr. Corneliu Giurgea was one of the first scientists who researched nootropics and attempted to define a number of features that would classify as such. According to his definition, a true nootropic may:

Improve learning and short-term memory retention Increase resilience to stress hormones and trauma Protect brain cells and improve brain bioactivity Promote intercellular communication

Have no side effects similar to other neuro-psychotropic drugs

While Nootropics can have many benefits for brain health, they shouldnt be used as a substitute for healthy habits. Getting enough sleep, eating a nutritious diet and managing stress are fundamental for achieving optimal cognitive performance, Chris DAdamo, PhD, at the University of Maryland, told WebMD. Once a person incorporates these changes into their life, nootropics can serve as an additional bonus for improving mental sharpness, reducing mental fatigue as well as the chances for age-related cognitive decline.

There are a wide range of brain boosters available, but some come with safety concerns and side effects. Thats why its so important to know what to look for when starting a search for nootropic supplements. The first distinction to make is between synthetic and natural nootropics.

Synthetic nootropics are manmade pills designed to boost cognitive functioning using chemical ingredients. So called smart drugs, such as Modafinil, Racetams, Adrafinil, and Noopept fall into this category. These compounds do improve mental function, but many also come with side effects and potential long-term consequences.

Take Modafinil, for example. This drug for people with sleep disorders is becoming a particularly popular choice to boost alertness and energy. While the research on Modafinil remains scant, looking at how the drug works may offer insight into possible side effects down the road.

Part of the way Modafinil works is by shifting the brains levels of norepinephrine, dopamine, serotonin, and other neurotransmitters; its not clear what effects these shifts may have on a persons health in the long run, as Markham Heid pointed out at TIME.

Common focus-enhancing pills like Ritalin and Adderall also classify as nootropics. These drugs are used widely both by ADHD patients and those without the condition and both groups experience their negative effects. Aside from being addictive, Adderall and Ritalin have been linked to insomnia, hallucinations, seizures, heart trouble, and sudden death in healthy individuals.

Many proponents of Giurgeas theory dont classify these drugs as nootropics.

If the side effects of synthetic nootropics arent reason enough to avoid them, consider the abundance of natural nootropics found in the natural world. Plants and herbs offer a wide range of adaptogenic, or stress-relieving compounds that support increased focus and relaxation.

Natural nootropics are much safer than synthetic forms because, in their purest version, they dont produce side effects similar to other neuro-psychotropic drugs. Look for high-quality nootropic herbs that are standardized or that feature certain trademarks or labels, such as GMP, which denotes good manufacturing practices. Also look for Nootropics without artificial ingredients or common allergens. Manufacturers concerned with safety will clearly define the presence of ingredients and allergens, such as gluten, soy, and dairy.

Heres a look at the best natural nootropics, and how they support the mind and body.

Green tea is a natural source of L-theanine, a common and efficient nootropic. Multiple studies have shown L-theanine to increase attention performance, improve sleep, boost reaction time, and promote relaxation. It could also be therapeutic for patients who suffer from high anxiety. These benefits are linked to L-theanines neuroprotective effects, meaning it can restore and regenerate nerve cells in multiple ways.

Brahmi, or Bacopa monnieri, is a fundamental herb in Ayurvedic medicine. It thrives in wet, tropical environments and can survive well under water. Similar to many other natural nootropics, the plant, its extract as well as isolated bacosides are known to support mental performance while reducing stress and having anti-inflammatory properties as well. Another perk of supplementing with Bacopa Monnieri is that it contains adaptogens, which fight off the free radicals and oxidative stress thatre linked to many modern lifestyle diseases, including heart disease, diabetes, and cancer.

Ginseng is one of the oldest and most popular adaptogenic herbs. Stemming from traditional Chinese medicine, its a long, light brown root with green leaves and a bitter flavor. The two most popular varieties are American (Panax quinquefolius) and Asian (Panax ginseng), both of which have a positive effect on the immune system.

Ginseng can support healthy blood sugar levels and increased concentration may help with menopause, cancer, blood pressure, and heart disease. Since ginseng is a powerful herb, it has the ability to interact with other drugs and may not be a good choice for people taking certain medications, so please consult with your doctor before taking Ginseng as a supplement.

Also known as rosenroot, arctic root, or golden root, rhodiola rosea is a mountain herb that grows in cold climates. It contains over 140 active ingredients and has both antidepressive and anti-fatigue effects and is also used to treat anxiety in Russia and Scandinavia. To test its antidepressive effects, a study compared rhodiola to the antidepressant medication Zoloft thats active ingredient is sertraline. Findings showed that, while the chemical drug had a greater effect on reducing overall symptoms of depression, the herb was easier to tolerate because it was generally without side effects.

Lions mane mushroom is a shaggy white mushroom that can be consumed cooked, raw, dried, or in tea form for improved brain function. While theres no definitive report linking lions mane to Alzheimers disease prevention, a study on mice has shown the mushroom to have neuroprotective impact on treating or preventing neurodegenerative diseases. These are often a cause of chronic inflammation, cell death, and brain damage in patients. More research is needed to see if the mushroom has the same effect in humans.

Lush and leafy, ginkgo biloba is one of the oldest living tree species. Its a popular natural nootropic that may have a positive effect on cognitive function, anxiety and stress management. Additionally, studies have shown the use of the herb to reduce symptoms of mild cognitive impairment and Alzheimers disease.

Gingko may play a role in improving blood flow, which can support artery health and reduce the chance of stroke. Other studies demonstrate the positive impacts of Gingko on eye health. More research is warranted, but preliminary findings suggest that supplementing with ginkgo biloba may be beneficial in treating age-related macular degeneration, the leading cause of vision loss.

The body only makes a very small amount of choline in the liver; however, it isnt sufficient to meet the needs of humans. Therefore, we must get it from our diet or from a choline supplement. Choline is often grouped with B vitamins due to its essential role in regulating liver function, metabolism, brain development, and muscle movement. While its rare to be deficient in choline, certain groups of people may be more at risk. These include endurance athletes, post menopausal women, pregnant women and people who consume high amounts of alcohol.

Piracetam is a natural nootropic that, like many others, is used for cognitive enhancement. It has been found that Piracetam may help working memory, intellectual function, learning, and concentration. Studies have also shown that Piracetam enhances ATP production, but when it comes to treating cognitive decline, the right dosage is key. A study of older adults showed significant difference in cognition improvement with a dosage of 1,600 mg three times per day. However, there was no difference in cognition with patients who received 800 mg three times per day.

An increased interest in brain health and productivity has given rise to a variety of synthetic supplements, but not all of these compounds are without concern. Since many synthetic nootropics may have side effects, natural nootropics are a much healthier and safer alternative.

Whether its improving mental performance, reducing the risk of disease, or raising your resilience against stress, natural nootropics offer a wide range of benefits for overall well-being and cognitive fitness. Understanding how to incorporate these supplements into your life can help you better understand your health and how to optimize it.

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London Nootropics adaptogenic coffee has all the perks without the crash – The Independent

Posted: October 19, 2022 at 3:04 pm

Whether youre a natural early bird or need some time to get started, theres nothing like a steaming cuppa to kickstart your day. While big names such Nespresso or Nescafe probably spring to mind first when thinking of home brew, there are many independent coffee brands that are just as good if not better.

If youre a fan of the BBCs Dragons Den, chances are youve heard of London Nootropics before. The pair of entrepreneurs behind this coffee brand received a 50,000 investment in the company when they appeared on the show in February.

London Nootropics does coffee a little differently than were used to, as it uses adaptogens. These are specific mushrooms, herbs and other plants that can help your body adapt to and cope with stress.

While not all these ingredients have scientific research to back up their effects on humans, some have been used in traditional medicine for thousands of years. Theyre also generally risk-free to use and their benefits range from reducing stress levels to improving memory and brain health.

So, with such bold claims to its name, we tried London Nootropics coffee blends for 12 days, to find out if it could live up to the hype.

We received a starter box (15, Londonnootropics.com), which contained four sachets of each blend available: zen, flow (previously grind) and mojo equal to 12 cups. Each blend is tailored for specific benefits and while zen should have a relaxing effect, mojo should be more performance-enhancing.

This starter box is a great introduction to the brand and can help you decide which blend works best for your needs, so you can then decide if you want to continue with the mixed box, switch to the mushroom blend box or a full box of one of the individual flavours in the future. Theres also bigger-sized boxes available and monthly subscriptions, which will save you between 3 and 12 per month.

We followed the instructions on the packaging, mixing one sachet with 300ml of hot water, and started tasting. We judged based on flavour, smell, benefits and how these blends compared with our regular morning coffee. After trying each of the blends on its own, we started adding in our favourite plant-based milk. We do recommend avoiding almond milk, as we noticed this resulted in a strange consistency. No cups were consumed past midday, as we didnt want to cause any sleepless nights.

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Keeping Your Brain In Shape Is Equally Important And Here’s How To Do It – Seen in the City

Posted: at 3:04 pm

Your brain is one of the most important organs in your body and its also one of the most delicate. Thats why its so important to take care of it and make sure youre doing everything you can to keep it healthy. Here are a few tips on how to do just that!

These are substances that can help to improve cognitive function. They can help you to think more clearly, and remember things more easily. There are many different kinds of nootropics available, so its worth doing some research to find the ones that will work best for you. When youre taking nootropics, its important to start with a low dose and increase it gradually over time.

Sleep is vital for brain health. When you sleep, your brain is able to rest and repair itself. This means that if youre not getting enough sleep, your brain wont be able to function as well as it should. Make sure youre getting at least eight hours of sleep every night, and try to stick to a regular sleep schedule as much as possible. There are a few things you can do to improve your sleep hygiene and get the most out of your slumber. Make sure your bedroom is dark and quiet. Avoid watching TV or using electronic devices in bed. Establish a regular sleep schedule and stick to it as much as possible. Get up and move around every few hours to keep your body active. Drink plenty of water during the day, and avoid drinking caffeine and alcohol before bedtime.

What you eat has a big impact on your brain health. Eating a diet thats high in healthy fats, antioxidants, and vitamins can help to improve cognitive function and protect the brain against damage. Conversely, a diet thats high in unhealthy foods can have a negative impact on your brain health. To keep your brain healthy, make sure youre eating plenty of fresh fruits and vegetables, whole grains, lean protein, and healthy fats. Avoid processed foods, sugary drinks, and excessive amounts of caffeine.

Exercise is good for your body but did you know its also good for your brain? Exercise has been shown to improve cognitive function and protect the brain against damage. It can also help to reduce stress levels and improve sleep quality. So if you want to keep your brain healthy, make sure youre getting plenty of exercises. Aim for at least 30 minutes of moderate exercise every day.

There are many different things you can do to keep your brain healthy. These are just a few of the most important things to remember. By following these tips, you can help to ensure that your brain is in the best possible shape. Make sure to get enough sleep, eat a healthy diet, and exercise regularly. And if you want to give your brain a boost, try taking some nootropics. With these simple tips, you can keep your brain healthy and improve your cognitive function.

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The keto diet and mental health: how closely should the food industry watch this trend? – FoodNavigator.com

Posted: at 3:04 pm

The ketogenic diet is high-fat, moderate-protein and low-carbohydrate. Ketogenic diets make the body produce ketones, which are used as an alternative fuel when blood sugar levels are low. Ketones are produced in the liver from fat, making the ketogenic diet a popular approach to weight loss.

There is also evidence emerging that the keto diet may help treat serious mental health disorders. A new clinical trial by James Cook University in Australia will undertake clinical trials to determine whether a diet high in fat and low in carbohydrates could be used to treat schizophrenia and bipolar disorder.

The way ketogenic therapy works is to provide alternative energy sources in the form of so-called ketone bodies (products of fat breakdown) and by helping to circumvent abnormally functioning cellular energy pathways in these mental disorders, said Associate Professor Carlo Longhitano, Head of Psychiatry at JCU and a co-investigator in the study.

He added that only well-designed and controlled clinical trials such as those now underway can allow conclusions that support evidence-based medicine. Without them it is just anecdotes and hearsay, said Dr Longhitano.

Andy Welch, CEO ofSeriously Low Carb, which sells products to over 250,000 consumers in 15 countries, stressed the wider, positive mental wellbeing effects of a healthy diet, but remains excited about the potential for ketos diets to answer many diverse problems including mental health.

Typically todays western diets lack a lot of the nutrients required to feed the body and look after our precious organs especially our brain, he told FoodNavigator. Introduce a keto diet, or aLow Carb Lifestyle, as I like to call it, and you essentially ditch many of the highly processed carbs and sugars that dominate Western lives. An appreciation of healthy foods like leafy greens and the essential nutrients they offer such as superior brain health sits at the heart of keto thinking, namely how to help your body operate at the peak of its powers.

In the case of leafy greens your brain gets what it needs at a nutrient level, functions better and as a result you will too. By maximizing your potential to appreciateeven the smallest experience, youfosteryour mental wellbeing.

Another way to think of low carb is the avoidance of bloatiness, he said, adding that a low carb lifestyle avoids or minimises access to these debilitating foods. If you feel better in your body then your mind has an indirect driver to also feel better. And thats just generic body benefits there are studies on Keto as a dietary intervention of Rheumatoid Arthritis providing anti-inflammatory benefits which result in patients experiencing significantly reduced pain. The less pain you feel the more likely you are to feel mentally robust.

EY Global Consumer Senior Analyst Jon Copestake, however, warned the food industry against throwing too much weight behind the keto movement.

I have a challenge with popular diets as being seen as defining trends. I still remember the excitement around the Atkins diet, the California beach diet and going back further supplementary diets like slimfast, he told FoodNavigator. Diets like Keto and Paleo are likely to go the way of every diet that preceded them in fading away when the next big thing comes along, but leaving a residual element of utility in the way consumers eat.

But he added there is a growing awareness among consumers to look to food to improve mood. What the diets point towards more broadly is an appetite to use diets not to define weight loss, which has typically always been the focus, but to also improve physical and mental well being, he told us. Skin health, brain health, sleep and relaxation are becoming just as prominent drivers of diet as weight loss which reflects a fairly fundamental change in the way consumers see their relationship with diets.

He added that its a challenge for brands responding to trends that may prove transient and potentially contradictory.

The number of fasting programs continues to grow, which puts brands out of the mix altogether. Some diets push people towards veganism, others focus on proteins and iron driving a much more red-meat based consumption, he explained.

From a brand perspective theres a threefold response. One is focused on reformulation. Increasing turmeric, kale, beetroot, pulses and omega-3 content in the prepared meals they sell to tap into a trend without completely falling for a fad that could change tomorrow. A second is launching supplements that specifically favour a trend this is where the drinks industry leads and the food industry follows nootropics, adaptogens, CBD, microbiome, probiotics, raw fermented products all started as drinks led mood enhancers that are bleeding into food through supplements which are increasingly sold as gummies.

"More recently the power of mushrooms seems to be becoming more prominent with mushroom gummies seen as the new mood enhancer because of their high nootropic and adaptogenic qualities rather than because of their psychedelic properties.

He recommended brands take a general health approach. Continuing on the same path of reducing unhealthy ingredients and increasing vegetable content, ramping up pulses and green ingredients- these dont respond to specific health fads but latch onto the longer term underlying trend and point to the fact that most dieticians generally see a balanced, healthy diets as delivering better physical and mental well being.

He also suggested food brands continue to their nod from evolving trends in the beverage industry.

Typically its much easier for drinks brands to be agile here and this is what theyve done, he elaborated. Mood and mental wellbeing enhancing drinks have gone from being virtually nowhere a decade ago to being almost ubiquitous today. From a food perspective its about tapping into the right trend and responding quickly. Food companies are increasingly using AI to trawl and analyse food trends through social media thanks to the predilection for younger consumers to publish a photo of every meal they have. From knowing whats hot theres a choice between driving emerging ingredients or food trends into your existing product formulation or creating new lines to accommodate them. The really interesting thing that Ive noticed is that, while drinks companies will adapt their portfolio for any dietary trend they can, food companies are much slower they take a wait and watch approach and have a lot of food safety and other regulation to consider. If you look at the 'diet' led assortment of ready meals in any supermarket today youd still find them dominated by calorie controlled foods rather than foods that promote energy levels or brain power.

For more on Food and Mood listen to the FoodNavigator Podcast, out October 19

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Nootropics revolution – patentability in the UK and EU – Lexology

Posted: October 13, 2022 at 1:01 pm

Data and commentary provided by Mathys & Squire has featured in an article byThe Nutraceutical Business Review, providing an update on the growth of the nootropics market.

A condensed version of the article is available below.

The global nootropic market is set to reach a value of $6.61 billion by 2026 at a compound annual growth rate of 13.7%, according to some projections. The term nootropic describes a broad category of nutraceuticals and pharmaceuticals offering cognitive function benefits. Caffeine is the most recognisable nootropic, but there are other examples that consumers will ingest on a regular basis, such as L-theanine (found in black and green tea), anthocyanins (found in blackberries), nicotine and creatine.

The increasing popularity of nutraceuticals, and particularly nootropics, appears to reflect consumers taking a more active approach to their health and wellbeing, as a consequence of evolving lifestyle choices, increased health awareness, and a shift toward a preventative healthcare paradigm.

Why are nootropics so popular?

Nootropics have established a wide and cross-generational appeal as individuals seek to biohack their cognitive function with supplements and functional foods.

Competitive gamers and eSports professionals are increasingly using nootropics to improve gaming performance. However, there is also a growing use of nootropics in sports nutrition by athletes, particularly those involved with team sports requiring swift decision making, motor control, coordination and timing. Nootropic sports drinks formulated with herbal nootropics for instance already exist and are marketed as helping improve focus, as well as energy levels.

It is not surprising that nootropics are also being marketed towards working professionals wanting to be more productive and stay focused, as well as to older generations wishing to retain mental acuity and stave off any mental decline.

Innovation driving popularity

Another notable reason for the increasing popularity of nootropics is that they are becoming more convenient and appetising to consume. Nootropic supplements are readily available in the form of chewable gummies, and in a variety of flavours, for those who have pill fatigue. In addition, nootropics are becoming increasingly prevalent in functional foods and beverages that can be integrated more readily into peoples existing routines. For example, there are nootropic snack bars, protein bars, performance drinks, stimulant-free functional beverages, and even adaptogenic coffee blends and alcohol-free nootropic mocktails.

The growth of personalised/individualised healthcare has also infiltrated the nootropics sector, as innovators have started offering personalised/individualised nootropic formulations determined by algorithms that take consumers responses to lifestyle questionnaires and convert them into a tailored formulation.

Protecting innovation

Unsurprisingly, the nootropics market is a hotbed for innovation, as companies fight to distinguish their products from those of their competitors and capitalise on the shift in consumer trends. Branding and marketing strategy play a significant role in the commercial success of such products, but innovators are also recognising the value in protecting their innovations through patents. New European patent applications in the food chemistry category increased by 6.1% in 2021 over the previous year, suggesting that the innovation seen in the sector is translating to increased numbers of patent filings year on year.

As with other food chemistry products, there are numerous options for protecting technical innovation underpinning nootropic products through patents. For instance, protecting a new composition or formulation of ingredients (including, for example, a synergistic stack of actives), and uses thereof, is often the most desirable protection sought by applicants.

There are also other patent protectable innovations relating to improvements in product bioavailability, organoleptics, shelf life, or for overcoming challenges to meet consumer preferences (e.g. to be derived from sustainable sources or to be vegan). There are also patentable innovations relating to extraction techniques of natural products and processing methods for producing a food product having, for instance, particularly high purity or particularly high active concentration, as well as new uses of known nutraceuticals that innovators may seek to protect.

Use claims (patents) at the EPO where things can get more complicated

Patenting nootropic products, or indeed any form of nutraceutical product, does not come without its challenges. The European Patent Office (EPO) does not, for instance, distinguish between a pharmaceutical or a nutraceutical product (for example, a functional food with a purported health benefit), which can be problematic when it comes to claiming the use of a nootropic product.

The EPO does not allow claims to methods of treatment of the human or animal body by surgery or therapy and many readers will know that claims relating to a medical use must be formulated in a specific manner to avoid such exclusions to patentability at the EPO. Nutraceutical products which may have a health benefit can fall into a grey area where they might not be intended for the treatment of a particular disease, but a claim to their use might be considered to constitute a method of treatment and therefore, fall foul of the exclusions.

Non-therapeutic / cosmetic method claims are allowable at the EPO, however, the non-therapeutic use must not be inseparably associated or inextricably linked with a therapeutic use which is not always clear. Some cosmetic methods can also help prevent disease. One can, for instance, imagine how there might be confusion if a nootropic product may improve cognitive performance in a healthy subject, but may have a therapeutic effect in a subject with a cognitive disorder.

Helpfully, a relatively recent EPO Board of Appeal decision T 1916/19 has clarified that a non-therapeutic method is allowable, so long as there are realisations of the claimed method that are purely non-therapeutic. Thus, in the case of the EPO, it seems that there are signs of a permissive approach to the assessment of non-therapeutic method claims, which is likely to be particularly welcome to nootropics innovators and the nutraceutical sector more widely.

Health claims (labelling) in Europe

Innovators in the nutraceutical sector must also navigate EU and UK regulation when seeking to market their innovative products. EU Regulation on food labelling and equivalent UK regulation prohibits labelling of foods with assertions that they prevent, treat or cure human diseases, which is understandable since they do not go through the same regulatory approval as medicinal products do. However, the regulation does allow assertions that a foodstuff reduces the risk of disease, provided it is listed on the EC Register of acceptable health claims.

If a nootropic or a nutraceutical product, cannot be marketed in the EU or UK as being useful for preventing or treating a human disease, how much value is there in granted patent claims directed to a medical use of a nutraceutical product? The answer to that is not so straightforward, but it certainly means that applicants should be considering ways to maximise the benefit of such claims, for instance by mirroring the allowable labelling language by referring to reducing the risk of a disease in the patent claim itself.

Summary

The nootropics sector is a particularly fast-growing branch of the nutraceuticals market which seems set to cement itself in the public consciousness in the future, if it hasnt already. It is clear that nootropics have a wide appeal to consumers and the innovations in the sector continue to mean that there are more options available for consumers to integrate nootropic products into their routine, and inevitably more options to biohack in a personalised and individualised fashion. Whilst there are certain hurdles for innovators to market such products, it is apparent that they can enjoy the full remit of patent protection for their innovations within the sector, at least as far as Europe and the UK are concerned.

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‘Sober’ drinks are popular: Why? Are they a good alcohol alternative? – USA TODAY

Posted: at 1:01 pm

This is how 'Dry January' affects your gut health

If youve decided to take on Dry January, you will probably start to see positive changes in your health like better sleep, clear complexion and improved mood.

Buzz60

From Dry January to Sober October, ditching alcohol continues to climb in popularity. With the trend not stopping anytime soon, products are hitting shelves marketed specifically to alcoholic drink ditchers.

But with ingredients like CBD, THC, nootropics and descriptions that boast mood-alteringeffects without alcohol, are these options really sobriety-friendly? Experts say there are a few things to consider.

"It really just depends onsomebody's definition of what sobriety means to them and how much they feel comfortable depending on the effects of these on their bodies and brains," says Hilary Sheinbaum, author of"The Dry Challenge:How to Lose the Booze for Dry January, Sober October,and Any Other Alcohol-Free Month."

For example, if someone issober from alcohol, Sheinbaum counts all these ingredients as qualifying. If someone's definition also includes cutting out marijuana, some of these options wouldn't be a fit.

It also depends what's in the product itself to determine if these aretrue sober alternatives."

"Products containing cannabis such as CBD typically dont produce intoxication, however they are psychoactive, soit is important to understand your personal reaction to these ingredients," explains Dana Amaya, a registered dietitian at Lenox Hill Hospital. "Cannabis ingredients containing THC are intoxicating, can interact with medications and medical conditions and one should speak with a health care professional if concerned."

'Sober October': Seven non-alcoholic cocktail recipes to try at home

Though a sober scale may be defined a bit differently by everyone, there is no question that these products are popular.

"People are looking for options that aren't going to have the damaging effects of alcohol but still allow them to sit back, relax, have a beverage that is considered sophisticated or more adult-like thana soda orsparkling water," Sheinbaum says. "It allows people to congregate and be social without the added pressure of imbibing."

In addition to an increase in non-alcoholic versions of beer, wine and cocktails, a new category of alcohol alternative drinks like Cann, which describes itself as a lightly carbonated "social tonic" infused with CBD and THC, are gaining popularity.

Celebs are taking notice too. There's Katy Perrys De Soi, which is described as a "non-alcoholic apritif"with natural botanicals and adaptogens, and the Bella Hadid-backed Kin Euphorics, an "aperitif-style, mood-boosting spirit" with nootropics.

"This markethas been booming," Sheinbaum adds."Younger generations are really drivingthis change... They still want to socialize, they still want to have fun, they still want to feel like they are part of the experience it's only going to go up from here."

Health has also become more top-of-mind.

Amayaincreasingly sees consumers choosing alcohol alternative drinks over alcoholic beverages due to "mounting health and wellness concerns."

"Consumers are also interested in avoiding the empty calories in alcohol, as well as 'next day regrets'often associated with alcoholic beverage consumption, resulting in reduced inhibition," she adds.

Though adaptogens and nootropics canboost calmness or elevate mood and thinking, theyhave not been shown to cause dependency like alcohol, Sheinbaum explains.

"You're not going to wake up the next morningfeeling hungover. You're not going to be 'drunk' off of nootropics or adaptogens and making decisions that perhaps you wouldn't make if you were not drinking."

In terms of CBD, Dr. Jessica Shepherd,chief medical officer of online health information platformVerywell Health,says it hasdemonstrated some efficacy in various physical andmental health issues, including depression, anxiety,neurologic disorders, such as seizures, andchronic pain issues.

Though popular, these drink options may not be a solutionfor everyone.

If you're someone curious about sobriety to boost health or skip out on hangovers, Sheinbaum explains, this type of swap makes sense. If you're someone who struggles with alcohol use disorder orstruggles with mental health challenges like severe anxiety, these options are not a replacementfor professional help.

"Anybody who wants to try these beverages instead ofalcohol, it's definitely a plus, but it's certainly also not a replacement for seeking help if that is something that somebody is struggling with," Sheinbaum says.

People should also be cautious if they're already on medication for something that's been clinically diagnosed, Shepherd says.

"This is not a substitute to that," she says. "Talk to your health care provider beforestopping a medication and taking on something like this."

Just as people have different reactions to alcohol, the same goes for other substances that may be in alternative products so buyers need to be aware.

CBD, for example, doesn't have much federal supervision. Like other supplementssold over-the-counter, very few areregulated by the Food and Drug Administration.

This means it's important for consumers to understand what they're drinking and for companies to bring more transparency as more brands are expected to hit the market.

"Go very slow initially until you understand your personal reaction to these ingredients," Amaya suggests.

Sheinbaum advises researching the ingredients in any product you're interested in trying and consulting with your doctor, especially if you take medications or have amedical condition.

Shepherd says it can help to keep realistic expectations when trying these products as well.

"If you aretaking it for something, say anxiety, depression, stress relief (it) may not alleviate all of those those types of feelings for a certain person," she says, suggesting instead a more well-rounded approach with meditation or therapy instead of "putting all the onus on one product to get you the complete outcome."

Forget 'Dry January': Alcohol-free beer, wine, cocktails are available year round and are gaining popularity

Alcohol, weed in moderation: What experts think of the 'California Sober' approach

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Almost Half Of US Adults Face Stress – This Company Believes Its Wearable Tech Is The Answer – Benzinga

Posted: at 1:01 pm

Maybe you have a Garmin or an Apple Watch to help you track how far you run or ride your bike and how much your heart rate increases when you exercise.

These devices are great for helping you achieve your fitness goals, but they dont actually do anything to improve your mental well-being.

But now a watch-like device thats designed to relieve stress is under development.

Los Angeles-based TruBrains wearable uses the vibrotherapy technology used in hospitals to soothe the users nervous system with safe, microsonic waves that increase blood flow, activate neurons and enhance neurotransmitter activity.

TruBrains unobtrusive Wearable device can be worn on the wrist or ankle and is a safe and effective method to nudge the parasympathetic nervous response in healthy adults.

Our mission is to empower people to do their best thinking, TruBrain Founder and CEO Chris Thompson said. The problems were trying to solve are stress and anxiety. That will clear the runway for you to focus more, relax and get better sleep.

In terms of the physical and emotional toll of increased stress, nearly half of US adults (49%) report their behavior has been negatively affected, according to the American Psychological Association. A staggering 94% of workers reported feeling stress at work.

With that data and the rapidly growing wearable market, Thompson believes that TruBrains Wearable, built by neuroscientists, is set up to succeed.

The global wearable technology market is expected to be worth $410.2 billion by 2026 growing at a compound annual growth rate of 31.2% driven by the prevalence of chronic diseases and obesity.

Weve reached profitability, and we have $18 million in historical sales, Thompson said. While this hardware is new for us, weve developed significant supply chain capabilities over the years, and we plan to apply some of those same principles to the wearable device space.

In addition to the Wearable still in development, TruBrain offers a line of nootropics blended to increase verbal fluency, avoid distractions and boost mental output. Their products are made by neuroscientists and based on decades of clinical research and brainwave measurements.

TruBrains most popular product is its 1-ounce nootropic drinks, which its website describes as personalized brain food. The drinks are formulated to help with sleep, relieve anxiety and fight procrastination and distractions. The company also offers brain fuel in the form of capsules, bars and powder sticks.

We are super excited about the potential of the wearables category, starting with this version in development, Thompson said. Our new launches are meant to be additive to our core product line not to cannibalize our products that are doing well in the market already. The beauty is it allows customers to test more options and angles to see what works best for their unique brain.

TruBrain is raising money on StartEngine to support the development of the Wearable. StartEngine allows nonaccredited investors to buy shares with under a $500 investment.

Featured photo provided by TruBrain.

Benzinga may receive monetary compensation from the issuer, or its agency, for publicizing the offering of the issuers securities. This content is for informational purposes only and is not intended to be investing advice. This is a paid ad. Please see 17b disclosure linked in the campaign page for more information.

TruBrain's Reg A+ offering is made available through StartEngine Primary, LLC, member FINRA /SIPC.This investment is speculative, illiquid, and involves a high degree of risk, including the possible loss of your entire investment. For more information about this offering, please view TruBrain's offering circular and risks associated with this offering.

This post contains sponsored advertising content. This content is for informational purposes only and is not intended to be investing advice.

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Focus On Functional Foods: 22 October | Feature Synopsis – The Grocer

Posted: September 22, 2022 at 12:08 pm

A pregnancy-aiding RTD beverage. Brain-boosting coffee. And dollops of fibre and protein. Food and drink makers have been squeezing nutrients into an ever-expanding array of food and drink. Some innovation is to get an edge over rivals. Some is to get positive points under the governments high fat, sugar and salt (HFSS) rules. And other times you wonder if its just because they can. So what is happening on the cutting edge of functional food innovation? What impact have the HFSS rules had now that implementation is imminent? And how is it affecting retail ranges and sales?

Nutrients: Which nutrients are proving most ripe for adding to food and drink? And what are consumers looking for when it comes to a better nutritional profile?

Categories: Fibre can be added to the likes of bread and breakfast bars, while protein is often put into a drink for a big hit before or after the gym. Which types of food and drink are seeing the most impressive functional innovation?

Nootropics: Sometimes called cognitive enhancers, nootropics are an emerging and contested addition to food and drink. Advocates say they improve brain function; critics disagree. Whats the state of play in the British market?

HFSS: Adding positive nutrients to products can improve their HFSS scores, allowing them to avoid restrictions. How much of a role has this played in functional benefits innovation?

Innovations: We will profile 4 new products or ranges that have ideally not appeared in The Grocer before. We need launch date, rsp, and a hi-res picture of each

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Nootropics That Actually Might Work, Say Experts Eat This Not That – Eat This, Not That

Posted: September 11, 2022 at 1:24 pm

People are turning to nootropics for a boost in mental performance, memory and creativity and the supplements, which are touted to improve and enhance cognitive functions, are gaining in popularity, but do they work? "While some of these claims may be exaggerated, there is evidence that some nootropics can offer some cognitive benefits," Dr. Tomi Mitchell, a Board-Certified Family Physician with Holistic Wellness Strategies tells us. Read on to learn about the most promising nootropics that have been shown to offer real benefits. As with all supplements and vitamins, it's important to talk with your physician first before taking to ensure there's no adverse side effects or interactions with current medications. Please consult your doctor for medical advice. Read onand to ensure your health and the health of others, don't miss these Sure Signs You've Already Had COVID.

Dr. Mitchell explains, "Nootropics are a type of supplement that is designed to improve cognitive function. The word "nootropic" comes from the Greek words for "mind" and "turning." Nootropics are sometimes called "smart drugs" or "cognitive enhancers." There is a wide variety of nootropics available on the market, and they can be used for a variety of purposes, including improving memory, focus, and task completion. Many people take nootropics in order to boost their productivity, and some even use them as a means of achieving better grades in school. Nootropics are also sometimes used as a treatment for conditions like ADHD and Alzheimer's disease. While there is still much research to be done on the efficacy of nootropics, many people swear by their benefits and continue to use them on a regular basis.

Nootropics are a type of supplement that is designed to improve cognitive function. The benefits of nootropics include improved memory, concentration, and focus. They can also help to reduce stress and anxiety levels. In addition, nootropics have been shown to boost brain power and protect the brain from age-related damage. Some of the most popular nootropics include ginkgo biloba, omega-3 fatty acids, and resveratrol. While more research is needed to confirm the effectiveness of these supplements, there is evidence that they can provide a range of health benefits. As such, nootropics are an increasingly popular choice for those looking to improve their cognitive function."

Dr. Mitchell tells us, "Although nootropics are generally considered to be safe and effective, there are some potential drawbacks to taking them. One of the most common concerns is that nootropics may interact with other medications or supplements, potentially resulting in dangerous side effects. Additionally, some people may experience negative effects such as headaches, nausea, or anxiety when taking nootropics. It is also important to note that the long-term effects of taking nootropics are not yet known. While they may improve cognitive function in the short term, it is possible that they could have negative consequences over time. As a result, anyone considering taking nootropics should speak with a healthcare provider first to ensure they are safe and appropriate for their individual needs."

Dr. Mitchell states, "Caffeine is a psychoactive substance that has long been employed as a cognitive enhancer. Current research indicates that caffeine improves various aspects of cognition, including attention, vigilance, and reaction time. In addition, caffeine appears to have positive effects on memory and learning. One mechanism by which caffeine may enhance cognition is by reducing sleepiness and fatigue. Caffeine also increases levels of the neurotransmitter dopamine, which plays a role in executive function and attention. Overall, the evidence suggests that caffeine can be an effective cognitive enhancer, particularly for sleep-deprived individuals or those with attention deficits. However, it is important to note that tolerance to the effects of caffeine can develop quickly, so regular users may need to consume increasing amounts of caffeine to maintain the same level of cognitive enhancement."6254a4d1642c605c54bf1cab17d50f1e

"Creatine is an amino acid or protein," Dr. Mitchell says. "It's found naturally in your body, mostly in your muscles, and it helps your muscles produce energy during heavy exercise. Creatine is also available as a dietary supplement. People take creatine as a performance-enhancing drug. Some research suggests that it might improve brain function in people with conditions that affect the brain, such as depression, Parkinson's disease, Huntington's disease, and Alzheimer's disease. However, there is not enough evidence to know if creatine has these effects. Creatine can cause side effects, including stomach pain and nausea. It can also cause weight gain and bloating. More research is needed to determine the long-term safety of taking creatine supplements. When used properly, creatine is generally considered safe. Consult with a doctor before taking any dietary supplements."

According to Dr. Mitchell, "Bacopa monnieri is a nootropic herb used in traditional Indian medicine for centuries. Also known as Brahmi, this herb is known for its memory-enhancing effects. Modern science has begun to back up these claims, and studies have shown that Bacopa can improve memory recall, attention span, and reaction time. Additionally, Bacopa has been shown to reduce stress and anxiety, making it a well-rounded nootropic. How does Bacopa work? The active compounds in Bacopa are thought to increase neurotransmitters like serotonin and dopamine, which play a role in cognitive function. Additionally, Bacopa is a powerful antioxidant, and it is thought that this property may help to protect the brain against age-related damage. Bacopa is an effective nootropic that can improve cognitive function and protect the brain against age-related damage. Bacopa monnieri is a herb used in traditional Indian medicine for centuries. Modern research has shown that it can improve memory and cognitive function in healthy adults."

Dr. Mitchell shares, "Ginkgo biloba is a popular nootropic herb used for centuries in Traditional Chinese Medicine. Today, Ginkgo Biloba is one of the most commonly used herbs for cognitive enhancement and memory improvement. So, how does ginkgo biloba work? Studies have shown that ginkgo Biloba can improve blood circulation to the brain, which may help to enhance cognitive function and memory. Additionally, ginkgo Biloba is thought to increase levels of acetylcholine, a neurotransmitter involved in learning and memory. Acetylcholine levels tend to decline with age, so increasing levels with Ginkgo Biloba may help to offset some of the age-related declines in cognitive function. Additionally, Ginkgo Biloba is a powerful antioxidant that can protect the brain from damage caused by free radicals. So, if you're looking for a natural way to boost your cognitive function and memory, Ginkgo Biloba may be worth trying."

"Rhodiola Rosea is a plant that grows in cold, mountainous regions of Europe and Asia," Dr. Mitchell says. "Also known as "golden root" or "arctic root," Rhodiola has been used for centuries to help counteract the effects of stress. Today, it is commonly sold as a supplement and is touted as a natural way to boost energy levels, improve cognitive function, and reduce stress. While some scientific evidence supports these claims, more research is needed to confirm the efficacy of Rhodiola Rosea as a nootropic.

Rhodiola Rosea is thought to work by affecting the serotonin and dopamine levels in the brain. These neurotransmitters are involved in regulating mood and psychological well-being. By increasing serotonin and dopamine levels, Rhodiola may help improve mood and alleviate symptoms of stress and anxiety. Additionally, Rhodiola is thought to increase ATP levels, the primary energy source in cells. This action may help to enhance physical stamina and cognitive function.

While Rhodiola Rosea shows promise as a nootropic, more research is needed to confirm its efficacy. Additionally, because it affects neurotransmitter levels, Rhodiola should be used with caution if you take medication for anxiety or depression. If you are considering using Rhodiola Rosea as a supplement, speak with your healthcare provider first to weigh the risks and benefits."

Dr. Mitchell says this "doesn't constitute medical advice and by no means are these answers meant to be comprehensive. Rather, it's to encourage discussions about health choices."

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