Category Archives: Nanotech

Details Created: 13 December 2013

[This Nanotech West Lab Research News article was contributed by the group of Prof. Ron Reano, Associate Professor of Electrical and Computer Engineering, and ElectroScience Laboratory, of The Ohio State University]

Silicon photonics is a promising approach for chip-scale integrated optics. A single-mode silicon strip waveguide designed for operation in the infrared, for example, has a typical submicron cross-section of 450 nm x 250 nm. Highly confined optical modes allow for high density integration and waveguide bends with micrometer scale radii of curvature. The high confinement, however, also produces major challenges when attempting to efficiently couple light between silicon strip waveguides and optical fibers. Mode conversion from a single-mode fiber, with mode field diameter equal to 10 micrometers, results in a coupling loss that is greater than 20 dB. Current methods designed to achieve efficient fiber-to-chip coupling generally involve edge coupling using inverse width tapered waveguides or surface coupling using grating couplers. Inverse width tapers enable low loss and broadband edge coupling but require dicing or cleaving the chip. Alternatively, grating couplers enable light coupling via the surface of the chip without the need for cleaving. They require, however, a tradeoff between bandwidth and efficiency.

Read more: Cantilever Couplers for Low-loss Fiber Coupling to Silicon Photonic Integrated Circuits

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Nanotech - Research

Welcome to SiO2 Nanotech we developed several ground breaking new technologies, including the optical anti-fog coating VitreOx and the Biomedical Testing technology HemaDrop. VitreOx is a patent pending anti-fog solution that produces a hydrophilic film to enhance vision clarity.

VitreOx can be used for a wide-range of applications, from surgical lenses, to athletic eyewear and beyond.

VitreOx is safe, entirely non-toxic to skin, eye and nose, effective, and lasting.

SiO2 NanoTech was incorporated in 2013 by Dr. Nicole Herbots and Clarizza Watson, and is located at the Center for Entrepreneurial Innovation (CEI) in Phoenix, Arizona.

VitreOx can be directly applied and used for temporary, semi- permanent and permanent anti-fog coatings on lenses, surfaces and medical devices. VitreOx INSTANTANEOUSLY eliminates fogging, by changing how water droplets behave on the surface, by producing a super hydrophilic surface. Instead of visible droplets (water beads), a uniform wet sheet instantly grows on the surface, resulting in a transparent surface instead of fogged lenses. Thus, VitreOx eliminates light scattering and the distortion of your vision by eliminating water droplets. Thus, VitreOx does not rely on heating, or evacuation to eliminate fogging.

In addition to VitreOx, SiO2 Nanotech is excited to announce our latest product we have developed HemaDrop, a technology used to analyze biological samples at the atomic level, using only a thousandth of the volume required in current biological testing. Using both HemaDrop and Ion Beam analysis, we are able to determine the exact atomic composition of samples such as blood or mucous. This analysis can be done quickly and can be repeated many times, ensuring accurate results within 5% error. With further development of this technology, we will be able to detect infectious diseases, chemical imbalances, and mineral deficiencies both portably and without the wait associated with current medical tests. Current Applications: Microscope slides Ruthersford Back Scattering (RBS) Analysis Kit Particle Induced X-Ray Emission (PIXE) Analysis Kit Spectrometry Analysis Kit Forensics

To learn more about VitreOx anti-fog technology, please contact us or call (602) 565-3447.

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Anti-fog Technology | VitreOx | SiO2 NanoTech

Join us in Washington DC for the 18th annual Nanotech 2016 Conference & Expo, co-located with the TechConnect World Innovation Conference, National Innovation Summit and National SBIR/STTR Conference. On behalf of our symposium organizers we warmly invite you to submit your research abstract and participate in this exciting international event.

Lloyd Whitman OSTP, Executive Office of the President

Stefanie Harvey TE Connectivity

Piotr Grodzinski National Cancer Institute

Harriet Kung Department of Energy

Dorothee Martin Saint-Gobain

Lisa Friedersdorf National Nanotechnology Coordination Office

Ara Nazarian Harvard Medical School

Thomas Gillespie In-Q-Tel

Stefanie Harvey TE Connectivity

Rushan Sakhibgareev Chevron

Prantik Mazumder Corning

Prithwiraj Maitra Johnson and Johnson

Steven Zullo NIBIB/NIH

Martin Schoeppler FUJIFILM Dimatix

Mike Cameron Sherwin Williams

Loucas Tsakalakos GE Global Research

Johan Pluyter International Flavors & Fragrances

Mandakini Kanugo Xerox Innovation Group

Jessica Tucker NIBIB

Brent Segal Lockheed Martin

YuanQiao Rao The Dow Chemical Company

Paul Vogt Momentive

Nicole F. Steinmetz Case Western Reserve University

Imre Gyuk DOE

Marcellino Gemelli Bosch Sensortec

Susana Addo Ntim US FDA

Lewis Sloter DOD

Loucas Tsakalakos GE Global Research

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Nanotech 2016 Conference - TechConnect World 2016

Join us in Washington DC for the 20th annual Nanotech 2017 Conference & Expo, co-located with the TechConnect World Innovation Conference, National Innovation Summit and National SBIR/STTR Conference. On behalf of our symposium organizers we warmly invite you to submit your research abstract and participate in this exciting international event.

Lloyd Whitman OSTP, Executive Office of the President

Stefanie Harvey TE Connectivity

Piotr Grodzinski National Cancer Institute

Harriet Kung Department of Energy

Dorothee Martin Saint-Gobain

Lisa Friedersdorf National Nanotechnology Coordination Office

Ara Nazarian Harvard Medical School

Thomas Gillespie In-Q-Tel

Stefanie Harvey TE Connectivity

Rushan Sakhibgareev Chevron

Prantik Mazumder Corning

Prithwiraj Maitra Johnson and Johnson

Steven Zullo NIBIB/NIH

Martin Schoeppler FUJIFILM Dimatix

Mike Cameron Sherwin Williams

Loucas Tsakalakos GE Global Research

Johan Pluyter International Flavors & Fragrances

Mandakini Kanugo Xerox Innovation Group

Jessica Tucker NIBIB

Brent Segal Lockheed Martin

YuanQiao Rao The Dow Chemical Company

Paul Vogt Momentive

Nicole F. Steinmetz Case Western Reserve University

Imre Gyuk DOE

Marcellino Gemelli Bosch Sensortec

Susana Addo Ntim US FDA

Lewis Sloter DOD

Loucas Tsakalakos GE Global Research

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Nanotech 2017 - techconnectworld.com

Moore Nanotechnology Systems, LLC (Nanotech) is dedicated to the development of ultra-precision machining systems and their successful utilization through the formation of lifelong customer partnerships. Total customer satisfaction of our products and services has always been, and will continue to be, our highest priority as we support our customers expansion into new markets through the design and development of new products, complimentary machine accessories, and enhancements to our existing products.

Our ultra-precision machine systems support single point diamond turning, deterministic micro-grinding, precision micro-milling, and glass press molding for the production of advanced optics including diamond turning sphere, asphere, freeform, conformal, lens array, and plano surfaces. We offer a diverse line of options and accessories to customize our machining platforms to suit our customers specific applications. From our state-of-the-art NFTS-6000 Fast Tool Servo systemto the industry's first touch swipe gesture interactive Windows based HMI, Nanotech builds to a higher standard of quality and reliability.

(click on a photo below to see a larger version)

Established in 1997, our abbreviated name Nanotech was from the beginning not only our registered trademark, but also a symbol of our commitment to developing highly advanced equipment and manufacturing processes capable of achieving nanometer level surface accuracies on advanced optical components. Our ultra-precision machining systems support many industries including consumer electronics, defense, aerospace, lighting, medical, automotive, and ophthalmic. Our world-class team of specialists has dedicated their careers to this technology, and their vision has made Nanotech the fastest growing company in this field.

For additional information visit our Machines Page. You can also E-mail Us or call 603-352-3030 to discuss your specific requirements.

Top 100 Private Companies in New Hampshire

From2010 through 2014, Business NH Magazine has ranked Moore Nanotechnology Systems as one of the top 100 private companies in the State of NH.

In addition, Moore Nanotechnology Systems, LLC was selected as 2008 Company of the Year by the State of New Hampshire Department of Economic Development

Dec. 3, 2008 Moore Nanotechnology Systems was lauded by Department of Resources and Economic Development Commissioner George Bald for its innovative spirit which have made it the fastest growing company in the precision machining field. read more >

Nanotech Reaches 100th 350FG / 650FGv2 Milestone Swanzey, NH May, 2015.

Nanotechhas announced customer acceptance oftheir 100th 350FG / 650FGv2 Y-axis Freeform Generator! The 650FGv2 is the latest version of their 5-axisfreeform system.It hasbecometheirglobal"flagship" machine.This is a significant milestone to surpassand a testament to the system's worldwide adoption by leading manufacturers. No other vertical axismachine compares toit's uniquesymmetric Y-axisdesignon any level. Performance, thermal stability, part cutting results,reliability as well as thelifelong technical service/support one receives are unmatched. Visit the 650FG Machine Page for complete details. Spend time with Nanotech anddiscover "Y"premier electro-optics companies choose to team with them.

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Moore Nanotechnology Systems: Ultra-Precision Machining Systems

Home > Directory > Nanotechnology Business Sites - Sorted by Name

Last Updated: Monday, 20-Apr-2015 19:51:34 PDT

Currently there are 534 businesses listed. If you know of another that is not shown, please contact us.

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Altimate EnviroCare "... photo-catalyst and ion exchange products capable of destroying microbial, mould, fungi and odour."

21st Century NanoTechnologies Single-walled carbon nanotubes (SWNT)

3DM Inc. "PuraMatrix, 3DM's innovative and award-winning family of biocompatible hydrogels ... nano-scale properties, synthetic origin, rigorously-tested biocompatability, stability and ease-of-use yield superior cell cultures, with applications in drug discovery, cancer and cell biology, toxicity screening, stem cell therapeutics and tissue engineering."

3rdTech Maker of the NanoManipulator

A123 Systems "... developer of a new generation of Lithium-Ion batteries that revolutionizes the way manufacturers design high power products. Founded in 2001, A123Systems proprietary nanoscale electrode technology is built on initial developments from Massachusetts Institute of Technology."

A&A Company "Thermal spray coatings and nano thermal spray coating using custom designed metal, ceramic, cermet and hard faced materials."

Ablynx "... a biopharmaceutical company engaged in the discovery and development of Nanobodies to treat a range of serious human diseases. Nanobodies are a novel class of antibody-derived therapeutic proteins."

Abraxis Oncology "The proprietary drug division of American Pharmaceutical Partners. ... dedicated to improving treatments for patients with cancer." Maker of Abraxane - paclitaxel protein-bound nano-particles for injectable suspension.

Abtech Scientific "... a biomedical diagnostics company that delivers biosensor devices, biosensor instruments and biosensor systems to the biomedical research community and the point of concern biomedical diagnostics market."

AccuFLEX Golf Company NanoShaft

Acrongenomics "... a publicly traded Nanobiotechnology company that specializes in the field of research and development of solutions in the fields of Genomics, Proteomics and Diagnostics."

AcryMed "... a development and manufacturing company focused on the introduction of novel medical products that help heal wounds or reduce infections."

Actel Corp. "... award winning single-chip FPGA solutions, including FPGAs based on antifuse and Flash technologies, high-performance intellectual property (IP) cores, integrated software development tools, programming tools, debug and demo boards, and design services."

Active Optical Networks "... advanced MEMS-based active optical components and subsystems to enhance the performance and wavelength management capabilities of optical networks."

Admatechs "Spherical shape particulates. Admatechs is a joint venture of Toyota Motor Corp., Shin-Etsu Chemical Co., Ltd., Shin-Etsu Quartz Products Co., Ltd., and other firms."

Advance Nanotech "Operating in three areas, electronics, biopharma and materials, Advance leverages relationships with financial and development resources to enable a product focused, fast-track commercialization of nanotechnology."

Advanced Battery Technologies "... develops, manufactures and distributes rechargeable polymer lithium-ion (PLI) batteries"

Advanced Fibers & Powders Technology development and advanced material manufacturing.

Advanced Diamond Technologies (ADT) "An early-stage company commercializing a patented technique for making thin films of nanocrystalline diamond. This novel material, which we call Ultrananocrystalline diamond (UNCD), is a form of natural diamondnot a diamond-like compound. UNCD possesses the material properties of natural diamond in thin film form."

Advanced Magnetics "... a developer of superparamagnetic iron oxide nanoparticles used in pharmaceutical products."

Advanced Micro Devices Microprocessor Solutions

Advanced Nano Coatings "... a producer of high performance, VOC compliant epoxy coatings."

Advanced Nano Products (ANP) Manufactures nanocrystalline materials and their chemical precursors for coating and powder processing applications.

Advanced Nano Technologies (ANT) Manufactures of a wide range of ultra fine and nanoscale powders.

Advanced Nanotechnology Limited (Advanced Nano) Manufactures a range of nanopowders and functional products that incorporate nanopowders.

Advanced Powders & Coatings (AP&C) Wholly-owned by Raymor Industries Inc. "... spherical metal powders."

Advanced Sensor Technologies "... developing and bringing to market a variety of miniature, sensor-based biotechnology devices for research and medical applications."

Advion BioSciences "... bioanalytical services and nanoelectrospray products."

Advectus Life Sciences"... an emerging life sciences company focused on the commercialization of a cure for brain cancer. Advectus holds the exclusive worldwide rights including patents to this nanoparticle-based technology for the delivery of approved cancer fighting drugs across the blood-brain barrier for the treatment of brain tumors."

Aegis Semiconductor "... wavelength-monitoring components and modules that are easily manufactured using proven methods from the semiconductor industry."

Affymetrix GeneChip(R) technology has become the industry standard in molecular biology research.

Agendia "... developed high-quality methods, using micro-array genetic profiling, for analyzing tumor samples and mapping the tumors specific properties."

Agere Systems (Formerly the Microelectronics division of Lucent Technologies) The "world leader in sales of communications components. We design, develop and manufacture optoelectronic components for communications networks, and integrated circuits for use in a broad range of communications and computer equipment."

Agilent "Agilent Technologies is on the leading edge of nearly every major trend in communications and life sciences. From optical and wireless communications to disease and discovery research, Agilent delivers product and technology innovations that benefit millions of people around the world."

Ahwahnee "... a leader in the mass production of Carbon Nanotubes (CNTs), creates high-energy, long-lasting and cost-effective CNT applications for a variety of industries."

Air Products and Chemicals "... atmospheric gases, process and specialty gases, performance materials and chemical intermediates."

Aktina Limited "Nano-engineered films for creating stable surface structures."

Akzo Nobel Coatings/Chemicals and Pharmaceuticals

AlCove Surfaces Medical device technology using special designed ceramic surfaces made of nanoporous aluminium oxide, applications such as local drug delivery or local brachytherapy. And nanostructured surfaces between 20 nm and 300 nm, changing the reflectivity, adhesion, wettability, and other properties.

ALD NanoSolutions "... commercialization strategy is founded on the assertion that new materials will be designed rather than discovered. The compelling opportunity is to identify and synthesize a new set of composite materials which are comprised of common substrates coated with specific material."

Alien Technology "... has developed, and holds exclusive patent rights to, a manufacturing technology that will dramatically reduce the manufacturing cost of a variety of electronic devices. The technology, called Fluidic Self-Assembly (FSA), permits the efficient assembly of Integrated Circuits into a variety of substrates, from glass to flexible plastic."

Allegro Technologies "... is a knowledge-based campus company. It has developed outstanding proprietary microdispensing technologies for current and next generation applications in the fields of drug discovery, genomics and analytical/diagnostic instrumentation."

Allomet Corporation Powered Metals

Almatis Specialty Alumina Materials

Alnair Labs "... established on 29th August 2001 with the aim to provide ultra-short pulse laser systems and solutions based on its unique carbon-nanotubes photonic technology."

Alnis BioSciences "... a drug development company with a potent, enabling therapeutic platform to treat cancer as well as infectious and inflammatory diseases. Alnis has engineered nanoscopic hydrogels, or NanoGels, comprised of polymers, bioactives, and targeting molecules."

Altair Nanomaterials A wholly-owned subsidiary of Altair Nanotechnologies Inc. Altair owns a proprietary technology for making nanocrystalline materials of unique quality, economically and in large quantities. The company produces closely-sized nanoparticles of titanium dioxide and related ceramic oxide materials and compounds.

Ambri Biosensor Technology "... pioneering the integration of Biotechnology, Nanotechnology and Electronics."

AMBIT Corporation "... developer of new and enabling technologies in a variety of fields where rapid commercialization is taking place."

American Elements "... a world leader in commercializing developments in materials science."

American Dye Source "... is now offering nano materials. These materials can be used for a variety of applications in display devices, security devices and heat reflecting devices."

American Superconductor "... supplier of dynamic reactive power grid stabilization products and the world's principal vendor of high temperature superconductor (HTS) wire and large rotating superconductor machinery."

AMICA Advanced Micro-electronic Center Aachen "Our research is dedicated to silicon process technology with a strong focus on nanolithography."

AMR Technologies "... develops, manufactures and distributes performance materials."

Amroy "Our latest product family is Hybtonite-nanoepoxies. Hybtonites can be used in marine, automotive, wind energy and in many industrial applications."

AMT Coatings "A technological based SME industry which deals with engineering coatings and advanced surface treatments for production of nanomaterials coatings (Electroplating, Electroless Plating, Anodising, PVD, etc.)."

Angstrom Medica "... a life-sciences biomaterials company that harnesses nanotechnology for orthopedic applications."

ANP Technologies "... develop cutting-edge technology platforms at the nano/bio interface and apply them in market sectors such as diagnostics/biodetection, protein/drug discovery, therapeutics, chem/bio defense, and homeland security."

Aonex Technologies A subsidiary of Arrowhead Research. "... focused on applying its technology to next-generation solar cells. Ultimately, the company seeks to enable devices with optical, logical, and amplification features on a single substrate."

AP Materials "Nanopowders and Nanotechnology for Advanced Materials."

ApNano Materials "... commercializes nanospheres and nanotubes of inorganic compounds discovered at the Weizmann Institute of Science in Rehovot, Israel. These materials are used in microelectronic, semiconductor, aerospace, lubricant and metal working markets." See funding article for more information.

Applied Materials "... supplier of products and services to the global semiconductor industry."

Applied Membranes "... a manufacturer and distributor for Reverse Osmosis Membranes, RO Systems and Components, both commercial and residential."

Applied MicroStructures Surface chemistry and modification.

Applied Nanotech A subsidiary of Nano-Proprietary, Inc. "Currently ANI is in advanced development for the application of electron emitting carbon nanotubes cathodes in a number of areas, including large area color televisions, new lighting devices, x-ray, and microwave generators."

Applied Sciences, Inc. (ASI) "a nationally recognized Research and Development company specializing in advanced materials and their applications. ASI is located near Dayton, Ohio, and consists of three additional affiliate companies, Pyrograf Products, Inc. (PPI), Nano Graphite Materials (NGM), and Aqua Locator."

Applied Thin Films (ATFI) "An advanced materials company developing thin film technologies to serve defense, energy, aerospace, and other industrial needs."

AQUANOVA German Solubilisate Technologies GmbH "As a scientifically orientated company AQUANOVA specialises in the development and production of clear, stable, water-free solubilisates of particles with a micelle structure for further processing in cosmetics, skin care products, pharmaceuticals, foodstuffs and nutritional supplements."

Arc Flash Corporation Photocatalyst coating material

Argonide A resource manufacturer for high purity nanoparticles, nanoscale ceramic fiber materials, and custom alloys.

Asahi Glass Co. A global materials and components supplier.

Asemblon "... specializing in the emerging field of self-assembling molecules or SAMs."

Asia Pacific Fuel Cell Technologies "... PEM fuel cells with technologies in stack design and manufacture, system integration and metal hydride hydrogen storage."

Asklepios BioPharmaceutical "... a biotechnology company engaged in the development and delivery of novel protein and cellular based therapies through design of proprietary Biological Nano Particles (BNP)."

Aspen Aerogels "Using patented technology, Spaceloft and Pyrogel materials combine a silica aerogel with reinforcing fibers to deliver proven thermal performance in the most efficient insulation available."

Atlas Mining "Halloysite is a high-value clay that sells for more than $400 per ton. Its fine particle size enables halloysite to be used extensively as a suspension agent in glaze preparations. The purity of the clay and the low iron and titania content result in ceramic ware with exceptional whiteness and translucency."

Authentix "Formed by the merger of Isotag, Biocode and Calyx in 2003, Authentix combines 20 years experience in providing comprehensive services and technology for the prevention of product counterfeiting, brand adulteration and product diversion."

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BASF BASF is one of the world leaders in the chemical industry, and currently produces several nano-products, such as nanoparticle pigments and nanoscale titanium dioxide particles. See also Nanotechnology at BASF

Baytubes "As a market- and customer-oriented inventor company, Bayer MaterialScience is working closely with Bayer Technology Services to promote the development of this exciting future technology (nanotubes)."

Beijing Nano Sunshine Technology Co. Ltd Nanocor's regional distributor in China

Bell Labs

BioCrystal "... semiconductor-based, nanocrystalline fluorescent markers for cell and intracellular detection and analysis; therapeutic compounds and procedures for the diagnosis and treatment of cancer; and the very innovative OptiCell , a product that represents a significant step forward in the evolution of cell and tissue culture technology."

BioForce Nanosciences "... developer of ultra-miniaturized nanoarray technologies for solid-phase, high-throughput biomolecular analysis."

Biophan Technologies "Biophan is developing technology to make biomedical devices safe, both implanted devices and those used in surgical and diagnostic procedures, and to reduce interference that these devices cause to Magnetic Resonance Imaging (MRI) image quality."

BioTrove "A privately held biotechnology company focused on leveraging revolutionary micro- and nano-scale engineering solutions that improve the efficiency and productivity of drug discovery."

Blue Pacific "... a leader in new flavor technology."

Bonderite NT Nanoceramic Technology

Bourne Research "... market intelligence, with a specialized focus on MEMS (MicroElectroMechanical Systems), Nanotechnology, and the convergence of both."

Brewer Science - Specialty Materials Division "Provides novel polymers and resins for use in MEMS device applications, Image Sensors and Flat Panel Displays."

BuckyUSA Specialty manufacturer of carbon nanomaterials.

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C Sixty "... a private biopharmaceutical company focusing on the discovery and the development of a new class of therapeutics based on the fullerene molecule ..."

Cabot Corporation "... our core businesses: carbon black, fumed metal oxides and tantalum. We've also found and developed them into new businesses: inkjet colorants, Nanogel and specialty fluids."

California Molecular Electronics Corporation "... committed to profitably invent, acquire, assimilate, and utilize intellectual property in the field of molecular electronics to develop and sell quality products based on molecular electronics technology ..."

Cambrios Technologies "... mission is to use biological technology to transform the way commercial electronic products are made, expand their impact, and reduce their environmental cost. Cambrios was formed in 2003 to develop commercial applications from the directed-evolution technology invented by the companys founders, Dr. Angela Belcher of MIT and her longtime collaborator, Dr. Evelyn Hu of the University of California at Santa Barbara."

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Nanotechnology Companies

The Rise of Graphene

Graphene is a rapidly rising star on the horizon of materials science and condensed-matter physics. This strictly two-dimensional material exhibits exceptionally high crystal...

AK Geim, KS Novoselov - Nature materials, 2007 nature.com

The Electronic Properties of Graphene

Carbon is the materia prima for life and the basis of all organic chemistry. Because of the flexibility of its bonding, carbon-based systems show an unlimited number of different

AHC Neto, F Guinea, NMR Peres, KS Novoselov Reviews of modern ,2009 - APS

December 17, 2015

Job Title: Scientist/Sr Scientist

Number: STG-201601 Nanotech Biomachines, Inc. Location: Berkeley, CA Nanotech Biomachines (Nanotech Bio) is a San Francisco Bay Area startup developing a breakthrough sensor technology for therapeutic discovery applications. Our core technology combines advances in electronics, chemistry, biochemistry, microfluidics, engineering, and software. Nanotech Bio is looking for an outstanding scientist to work on the Technology team. This position is a unique opportunity to work on a new form of analytical tool to enable desired discovery applications that were previously unachievable. This person will: (1) be a core member of the new Sensor Technology Group, (2) design and perform experiments of strategic value to the company, and (3) collaborate with marketing, engineering, software and chemistry groups to ensure products fit user needs and deliver promised results. The right candidate must have: (a) extensive knowledge of bioconjugation techniques (b) assay development experience (ELISA or sensor based) (c) experience with early versions of instrumentation. This position will work closely with team members in chemistry, biochemistry, microfluidics, engineering, and software. Key Responsibilities Development and optimization of biocompatible surface chemistry Development and optimization of methods for conjugation of surfaces to proteins and other molecules of interest Development of assays (quantitative and kinetic) on an early stage sensor Work closely with engineering team to assess instrument functionality and suggest improvements Troubleshooting of instrumentation, software, and assay issues Work with applications and marketing team to produce product documentation and publications Interface with key external scientists to promote publications and understand new product directions Desired Skills and Background Required experience in chemistry, biochemistry or biophysical chemistry BS with 5+ years of experience MS with 3+ years of experience PhD with 2+ years of experience Surface modification for development of biocompatible surfaces Solid phase assay development (ELISA or sensors) Protein immobilization and protein conjugation experience Testing of bread-board and prototype versions of instruments Experience with optical biosensors, thin film interferometery, surface plasmon resonance, or other label free techniques preferred Excellent verbal and written communication skills Working as a member of a diverse team Highly independent and self-driven Ability to work in a fast-paced and quickly changing environment Interested candidates should submit a complete resume and short cover letter to: careers@nanotechbio.com

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August 31, 2015

Job Title: Director of Technology

Number: 201502 Nanotech Biomachines, Inc. Location: Berkeley, CA Nanotech Biomachines (Nanotech Bio) is a San Francisco Bay Area startup developing a breakthrough sensor technology for therapeutic discovery applications. Our core technology combines advances in electronics, chemistry, biochemistry, microfluidics, engineering, and software. Nanotech Bio is looking for an outstanding individual to lead its Technology team. This position is a unique opportunity to work on a new form of analytical tool to enable desired discovery applications that were previously unachievable. This person will: (1) lead the expansion of the new Sensor Technology Group, (2) direct experiments of strategic value to the company, and (3) work with marketing, business, and product development management to ensure products fit users needs and deliver promised results. The right candidate must have: (a) A deep and broad expertise across label-free analysis, as well as extremely strong knowledge of binding technologies and their applications to bio-analytical assays in discovery and development operations, (b) Experience with semiconductor electronics and its bio-analytical physics, (c) Strong interpersonal and leadership skills, a burning desire to understand customer needs and mechanisms behind instrument performance, and the ability to communicate results clearly are essential. This position will work closely with team members in chemistry, biochemistry, microfluidics, engineering, and software. Key Responsibilities Lead a group of scientists and engineers drawn from a variety of backgrounds including biochemistry, chemistry, biology, engineering, electronics, and materials science Optimize current assays and drive the expansion of applications on existing products through new protocols Direct experiments of significant strategic value Work with the marketing and support teams to understand product performance in the field and provide feedback to aid with product development decisions Interface with key external scientists to promote publications and understand new product directions Be accountable for prioritization of groups activities and resources Desired Skills and Background PhD in biological field or bioengineering (e.g. biology, biochemistry, chemistry, biophysics, or bioengineering) 5+ years extensive industrial hands-on experience with label-free technologies and discovery assays 5+ years industrial experience leading multidisciplinary groups of scientists and engineers to meet product development milestones and deliverables for bio-analytical and/or diagnostic tool customers Deep and broad knowledge of discovery and binding assays Exceptional analytical ability and facility with electronics hardware An obsession with making sure customers are satisfied and products are a good fit in the market Highly independent and self-driven Ability to work in a fast-paced and quickly changing environment Interested candidates should submit a complete resume and short cover letter to: careers@nanotechbio.com

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NanoTech Biomachines - Graphene company

Transparent, flexible supercapacitors pave the way for a multitude of applications

(Phys.org)The standard appearance of today's electronic devices as solid, black objects could one day change completely as researchers make electronic components that are transparent and flexible. Working toward this goal, ...

(Phys.org)Scientists have built a battery containing a magnetic fluid that can be moved in any direction by applying a magnetic field. The magnetically controlled battery concept could be especially useful for flow batteries, ...

(Phys.org)One of the biggest problems plaguing high-energy, lithium-metal batteries is dendrites, which form when some of the lithium from the electrode begins to branch outside the electrode and into the electrolyte, ...

(Phys.org)Currently, all light-emitting diodes (LEDs) emit light of only one color, which is predefined during fabrication. So far, tuning the color of light produced by a single LED has never been realized, despite numerous ...

(Phys.org)Graphene has been grown from materials as diverse as plastic, cockroaches, Girl Scout cookies, and dog feces, and can theoretically be grown from any carbon source. However, scientists are still looking for a ...

(Phys.org)Electrons can move through graphene with almost no resistance, a property that gives graphene great potential for replacing silicon in next-generation, highly efficient electronic devices. But currently it's ...

(Phys.org)Researchers have designed and implemented an algorithm that solves computing problems using a strategy inspired by the way that an amoeba branches out to obtain resources. The new algorithm, called AmoebaSAT, ...

(Phys.org)In an act of "nano-alchemy," scientists have synthesized a silver (Ag) nanocluster that is virtually identical to a gold (Au) nanocluster. On the outside, the silver nanocluster has a golden yellow color, and ...

(Phys.org)Virtually all semiconductors used in today's electronic devices are made of silicon having a cubic crystal structure, as silicon naturally crystallizes in the cubic form. In a new study, researchers have fabricated ...

(Phys.org)Scientists have fabricated a flexible electrical circuit that, when cut into two pieces, can repair itself and fully restore its original conductivity. The circuit is made of a new gel that possesses a combination ...

(Phys.org)Scientists have proposed a new family of structures that are three-dimensional (3D) variations of graphene, the simplest example of which is called a "hyper-honeycomb." If the proposed structures can be experimentally ...

(Phys.org)Scientists have demonstrated that pinwheel-shaped microgears floating on a liquid surface can rotate at speeds of up to 300 r.p.m. when illuminated by an ordinary LED. This light-driven motion, which arises because ...

(Phys.org)Nanoscale motors, like their macroscale counterparts, can be built to run on a variety of chemical fuels, such as hydrogen peroxide and others. But unlike macroscale motors, some nanomotors can also run without ...

Scientists have developed a new technique that can print batteries on almost any surface, which is expected to be essential for future flexible electronics such as roll-up displays, smart electronic clothing, and Google Glass-type ...

(Phys.org)A new semiliquid battery developed by researchers at The University of Texas at Austin has exhibited encouraging early results, encompassing many of the features desired in a state-of-the-art energy-storage device. ...

(Phys.org)Researchers have proposed a new type of artificial neuron called a "straintronic spin neuron" that could serve as the basic unit of artificial neural networkssystems modeled on human brains that have the ability ...

(Phys.org)Researchers have developed the first imaging technique that can clearly see inside molecular structures, and have used it to create 3D holograms of the atomic arrangements inside these structures. Before now, ...

Electronic materials have been a major stumbling block for the advance of flexible electronics because existing materials do not function well after breaking and healing. A new electronic material created by an international ...

An International Space Station crew including an American, a Briton and a Russian landed safely Saturday in the sun-drenched steppes of Kazakhstan.

Hackers invited by the US government as part of a pilot program to find flaws with five Pentagon websites discovered 138 security vulnerabilities, Defense Secretary Ash Carter said Friday.

A simulation of the powerful jets generated by supermassive black holes at the centers of the largest galaxies explains why some burst forth as bright beacons visible across the universe, while others fall apart and never ...

On December 26, 2015 at 03:38:53 UTC, scientists observed gravitational wavesripples in the fabric of spacetimefor the second time.

If you're expecting to hear from aliens from across the universe, it could be a while.

First postulated more than 230 years ago, black holes have been extensively researched, frequently depicted, even featured in sci-fi films.

The Earth passed another unfortunate milestone May 23 when carbon dioxide (CO2) surpassed 400 parts per million (ppm) at the South Pole for the first time in 4 million years.

(Phys.org)European astronomers have uncovered evidence of a small glitch in the spin of a millisecond pulsar. According to a research paper published on June 13 on arXiv.org, the pulsar, designated PSR J0613-0200, exhibits ...

Carbon dioxide emissions from dry and oxygen-rich environments are likely to play a much greater role in controlling future rates of climate change caused by permafrost thaw than rates of methane release from oxygen-poor ...

Northwestern University astrophysicists have predicted history. In a new study, the scientists show their theoretical predictions last year were correct: The historic merger of two massive black holes detected Sept. 14, 2015, ...

May's temperatures broke global records yet again, as the northern hemisphere finishes its hottest spring on record, statistics released Tuesday by NASA showed.

(Phys.org)A large team of researchers from across the U.S. studying data sent back from Mars by the Curiosity rover has found evidence of tridymite, a type of mineral associated with explosive volcanoes here on Earth. ...

When an astronomical observatory detected two black holes colliding in deep space, scientists celebrated confirmation of Einstein's prediction of gravitational waves. A team of astrophysicists wondered something else: Had ...

Women live longer than men. This simple statement holds a tantalizing riddle that Steven Austad, Ph.D., and Kathleen Fischer, Ph.D., of the University of Alabama at Birmingham explore in a perspective piece published in Cell ...

In the Canadian province of Quebec, a study of more than 26,000 trees across an area the size of Spain forecasts potential winners and losers in a changing climate.

Light and matter are typically viewed as distinct entities that follow their own, unique rules. Matter has mass and typically exhibits interactions with other matter, while light is massless and does not interact with itself. ...

A facial recognition database compiled by the FBI has more than 400 million images to help criminal investigations, but lacks adequate safeguards for accuracy and privacy protection, a congressional audit shows.

Cats understand the principle of cause and effect as well as some elements of physics. Combining these abilities with their keen sense of hearing, they can predict where possible prey hides. These are the findings of researchers ...

Young stars much less massive than the Sun can unleash a torrent of X-ray radiation that can significantly shorten the lifetime of planet-forming disks surrounding these stars. This result comes from a new study of a group ...

Like a pair of human hands, certain organic molecules have mirror-image versions of themselves, a chemical property known as chirality. These so-called "handed" molecules are essential for biology and have intriguingly been ...

(Phys.org)A team of researchers with the University of Queensland's Centre for Sensorimotor Performance has found that running shoes alter the natural spring-like mechanics of the foot while a person is running. In their ...

Giant Ice Age species including elephant-sized sloths and powerful sabre-toothed cats that once roamed the windswept plains of Patagonia, southern South America, were finally felled by a perfect storm of a rapidly warming ...

A Stanford University research lab has developed new technologies to tackle two of the world's biggest energy challenges - clean fuel for transportation and grid-scale energy storage.

Weak coal and gas prices will not stop record investment in renewables over the coming decades as the cost of generating clean energy drops, a key energy report said Monday.

SpaceX successfully launched two satellites into orbit on Wednesday, but failed in an attempt to land the first stage of its Falcon 9 rocket undamaged on a barge in the Atlantic.

In the lead up to the World Barista Championships, University of Bath scientists say brewing more flavoursome coffee could be as simple as chilling the beans before grinding.

Researchers are investigating a new material that might help in nuclear fuel recycling and waste reduction by capturing certain gases released during reprocessing. Conventional technologies to remove these radioactive gases ...

In an essay to be published on June 17, 2016 in Science magazine Susan Landau, professor of cybersecurity policy at Worcester Polytechnic Institute (WPI), argues that the FBI's recent and widely publicized efforts to compel ...

The organic molecule methyl alcohol (methanol) has been found by the Atacama Large Millimeter/Submillimeter Array (ALMA) in the TW Hydrae protoplanetary disc. This is the first such detection of the compound in a young planet-forming ...

A federal appeals court on Tuesday upheld the government's "net neutrality" rules, preserving regulations that force internet providers such as Comcast and AT&T to treat all online trafficeverything from Netflix and cat ...

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The faculty, staff, and students of the Alan G. MacDiarmid NanoTech Institute at The University of Texas at Dallas welcome the 2012 class of NanoExplorers. We had over 200 highly qualified applicants this year. (see more)

Read about former NanoExplorer Amy Chyao and her work at UT Dallas

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NanoTech Institute - The University of Texas at Dallas

Nanotechnology ("nanotech") is manipulation of matter on an atomic, molecular, and supramolecular scale. The earliest, widespread description of nanotechnology[1][2] referred to the particular technological goal of precisely manipulating atoms and molecules for fabrication of macroscale products, also now referred to as molecular nanotechnology. A more generalized description of nanotechnology was subsequently established by the National Nanotechnology Initiative, which defines nanotechnology as the manipulation of matter with at least one dimension sized from 1 to 100 nanometers. This definition reflects the fact that quantum mechanical effects are important at this quantum-realm scale, and so the definition shifted from a particular technological goal to a research category inclusive of all types of research and technologies that deal with the special properties of matter which occur below the given size threshold. It is therefore common to see the plural form "nanotechnologies" as well as "nanoscale technologies" to refer to the broad range of research and applications whose common trait is size. Because of the variety of potential applications (including industrial and military), governments have invested billions of dollars in nanotechnology research. Until 2012, through its National Nanotechnology Initiative, the USA has invested 3.7 billion dollars, the European Union has invested 1.2 billion and Japan 750 million dollars.[3]

Nanotechnology as defined by size is naturally very broad, including fields of science as diverse as surface science, organic chemistry, molecular biology, semiconductor physics, microfabrication, etc.[4] The associated research and applications are equally diverse, ranging from extensions of conventional device physics to completely new approaches based upon molecular self-assembly, from developing new materials with dimensions on the nanoscale to direct control of matter on the atomic scale.

Scientists currently debate the future implications of nanotechnology. Nanotechnology may be able to create many new materials and devices with a vast range of applications, such as in nanomedicine, nanoelectronics, biomaterials energy production, and consumer products. On the other hand, nanotechnology raises many of the same issues as any new technology, including concerns about the toxicity and environmental impact of nanomaterials,[5] and their potential effects on global economics, as well as speculation about various doomsday scenarios. These concerns have led to a debate among advocacy groups and governments on whether special regulation of nanotechnology is warranted.

The concepts that seeded nanotechnology were first discussed in 1959 by renowned physicist Richard Feynman in his talk There's Plenty of Room at the Bottom, in which he described the possibility of synthesis via direct manipulation of atoms. The term "nano-technology" was first used by Norio Taniguchi in 1974, though it was not widely known.

Inspired by Feynman's concepts, K. Eric Drexler used the term "nanotechnology" in his 1986 book Engines of Creation: The Coming Era of Nanotechnology, which proposed the idea of a nanoscale "assembler" which would be able to build a copy of itself and of other items of arbitrary complexity with atomic control. Also in 1986, Drexler co-founded The Foresight Institute (with which he is no longer affiliated) to help increase public awareness and understanding of nanotechnology concepts and implications.

Thus, emergence of nanotechnology as a field in the 1980s occurred through convergence of Drexler's theoretical and public work, which developed and popularized a conceptual framework for nanotechnology, and high-visibility experimental advances that drew additional wide-scale attention to the prospects of atomic control of matter. In the 1980s, two major breakthroughs sparked the growth of nanotechnology in modern era.

First, the invention of the scanning tunneling microscope in 1981 which provided unprecedented visualization of individual atoms and bonds, and was successfully used to manipulate individual atoms in 1989. The microscope's developers Gerd Binnig and Heinrich Rohrer at IBM Zurich Research Laboratory received a Nobel Prize in Physics in 1986.[6][7] Binnig, Quate and Gerber also invented the analogous atomic force microscope that year.

Second, Fullerenes were discovered in 1985 by Harry Kroto, Richard Smalley, and Robert Curl, who together won the 1996 Nobel Prize in Chemistry.[8][9] C60 was not initially described as nanotechnology; the term was used regarding subsequent work with related graphene tubes (called carbon nanotubes and sometimes called Bucky tubes) which suggested potential applications for nanoscale electronics and devices.

In the early 2000s, the field garnered increased scientific, political, and commercial attention that led to both controversy and progress. Controversies emerged regarding the definitions and potential implications of nanotechnologies, exemplified by the Royal Society's report on nanotechnology.[10] Challenges were raised regarding the feasibility of applications envisioned by advocates of molecular nanotechnology, which culminated in a public debate between Drexler and Smalley in 2001 and 2003.[11]

Meanwhile, commercialization of products based on advancements in nanoscale technologies began emerging. These products are limited to bulk applications of nanomaterials and do not involve atomic control of matter. Some examples include the Silver Nano platform for using silver nanoparticles as an antibacterial agent, nanoparticle-based transparent sunscreens, carbon fiber strengthening using silica nanoparticles, and carbon nanotubes for stain-resistant textiles.[12][13]

Governments moved to promote and fund research into nanotechnology, such as in the U.S. with the National Nanotechnology Initiative, which formalized a size-based definition of nanotechnology and established funding for research on the nanoscale, and in Europe via the European Framework Programmes for Research and Technological Development.

By the mid-2000s new and serious scientific attention began to flourish. Projects emerged to produce nanotechnology roadmaps[14][15] which center on atomically precise manipulation of matter and discuss existing and projected capabilities, goals, and applications.

Nanotechnology is the engineering of functional systems at the molecular scale. This covers both current work and concepts that are more advanced. In its original sense, nanotechnology refers to the projected ability to construct items from the bottom up, using techniques and tools being developed today to make complete, high performance products.

One nanometer (nm) is one billionth, or 109, of a meter. By comparison, typical carbon-carbon bond lengths, or the spacing between these atoms in a molecule, are in the range 0.120.15 nm, and a DNA double-helix has a diameter around 2nm. On the other hand, the smallest cellular life-forms, the bacteria of the genus Mycoplasma, are around 200nm in length. By convention, nanotechnology is taken as the scale range 1 to 100 nm following the definition used by the National Nanotechnology Initiative in the US. The lower limit is set by the size of atoms (hydrogen has the smallest atoms, which are approximately a quarter of a nm diameter) since nanotechnology must build its devices from atoms and molecules. The upper limit is more or less arbitrary but is around the size that phenomena not observed in larger structures start to become apparent and can be made use of in the nano device.[16] These new phenomena make nanotechnology distinct from devices which are merely miniaturised versions of an equivalent macroscopic device; such devices are on a larger scale and come under the description of microtechnology.[17]

To put that scale in another context, the comparative size of a nanometer to a meter is the same as that of a marble to the size of the earth.[18] Or another way of putting it: a nanometer is the amount an average man's beard grows in the time it takes him to raise the razor to his face.[18]

Two main approaches are used in nanotechnology. In the "bottom-up" approach, materials and devices are built from molecular components which assemble themselves chemically by principles of molecular recognition. In the "top-down" approach, nano-objects are constructed from larger entities without atomic-level control.[19]

Areas of physics such as nanoelectronics, nanomechanics, nanophotonics and nanoionics have evolved during the last few decades to provide a basic scientific foundation of nanotechnology.

Several phenomena become pronounced as the size of the system decreases. These include statistical mechanical effects, as well as quantum mechanical effects, for example the quantum size effect where the electronic properties of solids are altered with great reductions in particle size. This effect does not come into play by going from macro to micro dimensions. However, quantum effects can become significant when the nanometer size range is reached, typically at distances of 100 nanometers or less, the so-called quantum realm. Additionally, a number of physical (mechanical, electrical, optical, etc.) properties change when compared to macroscopic systems. One example is the increase in surface area to volume ratio altering mechanical, thermal and catalytic properties of materials. Diffusion and reactions at nanoscale, nanostructures materials and nanodevices with fast ion transport are generally referred to nanoionics. Mechanical properties of nanosystems are of interest in the nanomechanics research. The catalytic activity of nanomaterials also opens potential risks in their interaction with biomaterials.

Materials reduced to the nanoscale can show different properties compared to what they exhibit on a macroscale, enabling unique applications. For instance, opaque substances can become transparent (copper); stable materials can turn combustible (aluminium); insoluble materials may become soluble (gold). A material such as gold, which is chemically inert at normal scales, can serve as a potent chemical catalyst at nanoscales. Much of the fascination with nanotechnology stems from these quantum and surface phenomena that matter exhibits at the nanoscale.[20]

Modern synthetic chemistry has reached the point where it is possible to prepare small molecules to almost any structure. These methods are used today to manufacture a wide variety of useful chemicals such as pharmaceuticals or commercial polymers. This ability raises the question of extending this kind of control to the next-larger level, seeking methods to assemble these single molecules into supramolecular assemblies consisting of many molecules arranged in a well defined manner.

These approaches utilize the concepts of molecular self-assembly and/or supramolecular chemistry to automatically arrange themselves into some useful conformation through a bottom-up approach. The concept of molecular recognition is especially important: molecules can be designed so that a specific configuration or arrangement is favored due to non-covalent intermolecular forces. The WatsonCrick basepairing rules are a direct result of this, as is the specificity of an enzyme being targeted to a single substrate, or the specific folding of the protein itself. Thus, two or more components can be designed to be complementary and mutually attractive so that they make a more complex and useful whole.

Such bottom-up approaches should be capable of producing devices in parallel and be much cheaper than top-down methods, but could potentially be overwhelmed as the size and complexity of the desired assembly increases. Most useful structures require complex and thermodynamically unlikely arrangements of atoms. Nevertheless, there are many examples of self-assembly based on molecular recognition in biology, most notably WatsonCrick basepairing and enzyme-substrate interactions. The challenge for nanotechnology is whether these principles can be used to engineer new constructs in addition to natural ones.

Molecular nanotechnology, sometimes called molecular manufacturing, describes engineered nanosystems (nanoscale machines) operating on the molecular scale. Molecular nanotechnology is especially associated with the molecular assembler, a machine that can produce a desired structure or device atom-by-atom using the principles of mechanosynthesis. Manufacturing in the context of productive nanosystems is not related to, and should be clearly distinguished from, the conventional technologies used to manufacture nanomaterials such as carbon nanotubes and nanoparticles.

When the term "nanotechnology" was independently coined and popularized by Eric Drexler (who at the time was unaware of an earlier usage by Norio Taniguchi) it referred to a future manufacturing technology based on molecular machine systems. The premise was that molecular scale biological analogies of traditional machine components demonstrated molecular machines were possible: by the countless examples found in biology, it is known that sophisticated, stochastically optimised biological machines can be produced.

It is hoped that developments in nanotechnology will make possible their construction by some other means, perhaps using biomimetic principles. However, Drexler and other researchers[21] have proposed that advanced nanotechnology, although perhaps initially implemented by biomimetic means, ultimately could be based on mechanical engineering principles, namely, a manufacturing technology based on the mechanical functionality of these components (such as gears, bearings, motors, and structural members) that would enable programmable, positional assembly to atomic specification.[22] The physics and engineering performance of exemplar designs were analyzed in Drexler's book Nanosystems.

In general it is very difficult to assemble devices on the atomic scale, as one has to position atoms on other atoms of comparable size and stickiness. Another view, put forth by Carlo Montemagno,[23] is that future nanosystems will be hybrids of silicon technology and biological molecular machines. Richard Smalley argued that mechanosynthesis are impossible due to the difficulties in mechanically manipulating individual molecules.

This led to an exchange of letters in the ACS publication Chemical & Engineering News in 2003.[24] Though biology clearly demonstrates that molecular machine systems are possible, non-biological molecular machines are today only in their infancy. Leaders in research on non-biological molecular machines are Dr. Alex Zettl and his colleagues at Lawrence Berkeley Laboratories and UC Berkeley.[1] They have constructed at least three distinct molecular devices whose motion is controlled from the desktop with changing voltage: a nanotube nanomotor, a molecular actuator,[25] and a nanoelectromechanical relaxation oscillator.[26] See nanotube nanomotor for more examples.

An experiment indicating that positional molecular assembly is possible was performed by Ho and Lee at Cornell University in 1999. They used a scanning tunneling microscope to move an individual carbon monoxide molecule (CO) to an individual iron atom (Fe) sitting on a flat silver crystal, and chemically bound the CO to the Fe by applying a voltage.

The nanomaterials field includes subfields which develop or study materials having unique properties arising from their nanoscale dimensions.[29]

These seek to arrange smaller components into more complex assemblies.

These seek to create smaller devices by using larger ones to direct their assembly.

These seek to develop components of a desired functionality without regard to how they might be assembled.

These subfields seek to anticipate what inventions nanotechnology might yield, or attempt to propose an agenda along which inquiry might progress. These often take a big-picture view of nanotechnology, with more emphasis on its societal implications than the details of how such inventions could actually be created.

Nanomaterials can be classified in 0D, 1D, 2D and 3D nanomaterials. The dimensionality play a major role in determining the characteristic of nanomaterials including physical, chemical and biological characteristics. With the decrease in dimensionality, an increase in surface-to-volume ratio is observed. This indicate that smaller dimensional nanomaterials have higher surface area compared to 3D nanomaterials. Recently, two dimensional (2D) nanomaterials are extensively investigated for electronic, biomedical, drug delivery and biosensor applications.

There are several important modern developments. The atomic force microscope (AFM) and the Scanning Tunneling Microscope (STM) are two early versions of scanning probes that launched nanotechnology. There are other types of scanning probe microscopy. Although conceptually similar to the scanning confocal microscope developed by Marvin Minsky in 1961 and the scanning acoustic microscope (SAM) developed by Calvin Quate and coworkers in the 1970s, newer scanning probe microscopes have much higher resolution, since they are not limited by the wavelength of sound or light.

The tip of a scanning probe can also be used to manipulate nanostructures (a process called positional assembly). Feature-oriented scanning methodology may be a promising way to implement these nanomanipulations in automatic mode.[44][45] However, this is still a slow process because of low scanning velocity of the microscope.

Various techniques of nanolithography such as optical lithography, X-ray lithography dip pen nanolithography, electron beam lithography or nanoimprint lithography were also developed. Lithography is a top-down fabrication technique where a bulk material is reduced in size to nanoscale pattern.

Another group of nanotechnological techniques include those used for fabrication of nanotubes and nanowires, those used in semiconductor fabrication such as deep ultraviolet lithography, electron beam lithography, focused ion beam machining, nanoimprint lithography, atomic layer deposition, and molecular vapor deposition, and further including molecular self-assembly techniques such as those employing di-block copolymers. The precursors of these techniques preceded the nanotech era, and are extensions in the development of scientific advancements rather than techniques which were devised with the sole purpose of creating nanotechnology and which were results of nanotechnology research.

The top-down approach anticipates nanodevices that must be built piece by piece in stages, much as manufactured items are made. Scanning probe microscopy is an important technique both for characterization and synthesis of nanomaterials. Atomic force microscopes and scanning tunneling microscopes can be used to look at surfaces and to move atoms around. By designing different tips for these microscopes, they can be used for carving out structures on surfaces and to help guide self-assembling structures. By using, for example, feature-oriented scanning approach, atoms or molecules can be moved around on a surface with scanning probe microscopy techniques.[44][45] At present, it is expensive and time-consuming for mass production but very suitable for laboratory experimentation.

In contrast, bottom-up techniques build or grow larger structures atom by atom or molecule by molecule. These techniques include chemical synthesis, self-assembly and positional assembly. Dual polarisation interferometry is one tool suitable for characterisation of self assembled thin films. Another variation of the bottom-up approach is molecular beam epitaxy or MBE. Researchers at Bell Telephone Laboratories like John R. Arthur. Alfred Y. Cho, and Art C. Gossard developed and implemented MBE as a research tool in the late 1960s and 1970s. Samples made by MBE were key to the discovery of the fractional quantum Hall effect for which the 1998 Nobel Prize in Physics was awarded. MBE allows scientists to lay down atomically precise layers of atoms and, in the process, build up complex structures. Important for research on semiconductors, MBE is also widely used to make samples and devices for the newly emerging field of spintronics.

However, new therapeutic products, based on responsive nanomaterials, such as the ultradeformable, stress-sensitive Transfersome vesicles, are under development and already approved for human use in some countries.[citation needed]

As of August 21, 2008, the Project on Emerging Nanotechnologies estimates that over 800 manufacturer-identified nanotech products are publicly available, with new ones hitting the market at a pace of 34 per week.[13] The project lists all of the products in a publicly accessible online database. Most applications are limited to the use of "first generation" passive nanomaterials which includes titanium dioxide in sunscreen, cosmetics, surface coatings,[46] and some food products; Carbon allotropes used to produce gecko tape; silver in food packaging, clothing, disinfectants and household appliances; zinc oxide in sunscreens and cosmetics, surface coatings, paints and outdoor furniture varnishes; and cerium oxide as a fuel catalyst.[12]

Further applications allow tennis balls to last longer, golf balls to fly straighter, and even bowling balls to become more durable and have a harder surface. Trousers and socks have been infused with nanotechnology so that they will last longer and keep people cool in the summer. Bandages are being infused with silver nanoparticles to heal cuts faster.[47]Video game consoles and personal computers may become cheaper, faster, and contain more memory thanks to nanotechnology.[48] Nanotechnology may have the ability to make existing medical applications cheaper and easier to use in places like the general practitioner's office and at home.[49] Cars are being manufactured with nanomaterials so they may need fewer metals and less fuel to operate in the future.[50]

Scientists are now turning to nanotechnology in an attempt to develop diesel engines with cleaner exhaust fumes. Platinum is currently used as the diesel engine catalyst in these engines. The catalyst is what cleans the exhaust fume particles. First a reduction catalyst is employed to take nitrogen atoms from NOx molecules in order to free oxygen. Next the oxidation catalyst oxidizes the hydrocarbons and carbon monoxide to form carbon dioxide and water.[51] Platinum is used in both the reduction and the oxidation catalysts.[52] Using platinum though, is inefficient in that it is expensive and unsustainable. Danish company InnovationsFonden invested DKK 15 million in a search for new catalyst substitutes using nanotechnology. The goal of the project, launched in the autumn of 2014, is to maximize surface area and minimize the amount of material required. Objects tend to minimize their surface energy; two drops of water, for example, will join to form one drop and decrease surface area. If the catalyst's surface area that is exposed to the exhaust fumes is maximized, efficiency of the catalyst is maximized. The team working on this project aims to create nanoparticles that will not merge. Every time the surface is optimized, material is saved. Thus, creating these nanoparticles will increase the effectiveness of the resulting diesel engine catalystin turn leading to cleaner exhaust fumesand will decrease cost. If successful, the team hopes to reduce platinum use by 25%.[53]

Nanotechnology also has a prominent role in the fast developing field of Tissue Engineering. When designing scaffolds, researchers attempt to the mimic the nanoscale features of a Cell's microenvironment to direct its differentiation down a suitable lineage.[54] For example, when creating scaffolds to support the growth of bone, researchers may mimic osteoclast resorption pits.[55]

Researchers have successfully used DNA origami-based nanobots capable of carrying out logic functions to achieve targeted drug delivery in cockroaches. It is said that the computational power of these nanobots can be scaled up to that of a Commodore 64.[56]

An area of concern is the effect that industrial-scale manufacturing and use of nanomaterials would have on human health and the environment, as suggested by nanotoxicology research. For these reasons, some groups advocate that nanotechnology be regulated by governments. Others counter that overregulation would stifle scientific research and the development of beneficial innovations. Public health research agencies, such as the National Institute for Occupational Safety and Health are actively conducting research on potential health effects stemming from exposures to nanoparticles.[57][58]

Some nanoparticle products may have unintended consequences. Researchers have discovered that bacteriostatic silver nanoparticles used in socks to reduce foot odor are being released in the wash.[59] These particles are then flushed into the waste water stream and may destroy bacteria which are critical components of natural ecosystems, farms, and waste treatment processes.[60]

Public deliberations on risk perception in the US and UK carried out by the Center for Nanotechnology in Society found that participants were more positive about nanotechnologies for energy applications than for health applications, with health applications raising moral and ethical dilemmas such as cost and availability.[61]

Experts, including director of the Woodrow Wilson Center's Project on Emerging Nanotechnologies David Rejeski, have testified[62] that successful commercialization depends on adequate oversight, risk research strategy, and public engagement. Berkeley, California is currently the only city in the United States to regulate nanotechnology;[63]Cambridge, Massachusetts in 2008 considered enacting a similar law,[64] but ultimately rejected it.[65] Relevant for both research on and application of nanotechnologies, the insurability of nanotechnology is contested.[66] Without state regulation of nanotechnology, the availability of private insurance for potential damages is seen as necessary to ensure that burdens are not socialised implicitly.

Nanofibers are used in several areas and in different products, in everything from aircraft wings to tennis rackets. Inhaling airborne nanoparticles and nanofibers may lead to a number of pulmonary diseases, e.g. fibrosis.[67] Researchers have found that when rats breathed in nanoparticles, the particles settled in the brain and lungs, which led to significant increases in biomarkers for inflammation and stress response[68] and that nanoparticles induce skin aging through oxidative stress in hairless mice.[69][70]

A two-year study at UCLA's School of Public Health found lab mice consuming nano-titanium dioxide showed DNA and chromosome damage to a degree "linked to all the big killers of man, namely cancer, heart disease, neurological disease and aging".[71]

A major study published more recently in Nature Nanotechnology suggests some forms of carbon nanotubes a poster child for the nanotechnology revolution could be as harmful as asbestos if inhaled in sufficient quantities. Anthony Seaton of the Institute of Occupational Medicine in Edinburgh, Scotland, who contributed to the article on carbon nanotubes said "We know that some of them probably have the potential to cause mesothelioma. So those sorts of materials need to be handled very carefully."[72] In the absence of specific regulation forthcoming from governments, Paull and Lyons (2008) have called for an exclusion of engineered nanoparticles in food.[73] A newspaper article reports that workers in a paint factory developed serious lung disease and nanoparticles were found in their lungs.[74][75][76][77]

Calls for tighter regulation of nanotechnology have occurred alongside a growing debate related to the human health and safety risks of nanotechnology.[78] There is significant debate about who is responsible for the regulation of nanotechnology. Some regulatory agencies currently cover some nanotechnology products and processes (to varying degrees) by bolting on nanotechnology to existing regulations there are clear gaps in these regimes.[79] Davies (2008) has proposed a regulatory road map describing steps to deal with these shortcomings.[80]

Stakeholders concerned by the lack of a regulatory framework to assess and control risks associated with the release of nanoparticles and nanotubes have drawn parallels with bovine spongiform encephalopathy ("mad cow" disease), thalidomide, genetically modified food,[81] nuclear energy, reproductive technologies, biotechnology, and asbestosis. Dr. Andrew Maynard, chief science advisor to the Woodrow Wilson Centers Project on Emerging Nanotechnologies, concludes that there is insufficient funding for human health and safety research, and as a result there is currently limited understanding of the human health and safety risks associated with nanotechnology.[82] As a result, some academics have called for stricter application of the precautionary principle, with delayed marketing approval, enhanced labelling and additional safety data development requirements in relation to certain forms of nanotechnology.[83][84]

The Royal Society report[10] identified a risk of nanoparticles or nanotubes being released during disposal, destruction and recycling, and recommended that manufacturers of products that fall under extended producer responsibility regimes such as end-of-life regulations publish procedures outlining how these materials will be managed to minimize possible human and environmental exposure (p. xiii).

The Center for Nanotechnology in Society has found that people respond to nanotechnologies differently, depending on application with participants in public deliberations more positive about nanotechnologies for energy than health applications suggesting that any public calls for nano regulations may differ by technology sector.[61]

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