The Prometheus League
Breaking News and Updates
- Abolition Of Work
- Ai
- Alt-right
- Alternative Medicine
- Antifa
- Artificial General Intelligence
- Artificial Intelligence
- Artificial Super Intelligence
- Ascension
- Astronomy
- Atheism
- Atheist
- Atlas Shrugged
- Automation
- Ayn Rand
- Bahamas
- Bankruptcy
- Basic Income Guarantee
- Big Tech
- Bitcoin
- Black Lives Matter
- Blackjack
- Boca Chica Texas
- Brexit
- Caribbean
- Casino
- Casino Affiliate
- Cbd Oil
- Censorship
- Cf
- Chess Engines
- Childfree
- Cloning
- Cloud Computing
- Conscious Evolution
- Corona Virus
- Cosmic Heaven
- Covid-19
- Cryonics
- Cryptocurrency
- Cyberpunk
- Darwinism
- Democrat
- Designer Babies
- DNA
- Donald Trump
- Eczema
- Elon Musk
- Entheogens
- Ethical Egoism
- Eugenic Concepts
- Eugenics
- Euthanasia
- Evolution
- Extropian
- Extropianism
- Extropy
- Fake News
- Federalism
- Federalist
- Fifth Amendment
- Fifth Amendment
- Financial Independence
- First Amendment
- Fiscal Freedom
- Food Supplements
- Fourth Amendment
- Fourth Amendment
- Free Speech
- Freedom
- Freedom of Speech
- Futurism
- Futurist
- Gambling
- Gene Medicine
- Genetic Engineering
- Genome
- Germ Warfare
- Golden Rule
- Government Oppression
- Hedonism
- High Seas
- History
- Hubble Telescope
- Human Genetic Engineering
- Human Genetics
- Human Immortality
- Human Longevity
- Illuminati
- Immortality
- Immortality Medicine
- Intentional Communities
- Jacinda Ardern
- Jitsi
- Jordan Peterson
- Las Vegas
- Liberal
- Libertarian
- Libertarianism
- Liberty
- Life Extension
- Macau
- Marie Byrd Land
- Mars
- Mars Colonization
- Mars Colony
- Memetics
- Micronations
- Mind Uploading
- Minerva Reefs
- Modern Satanism
- Moon Colonization
- Nanotech
- National Vanguard
- NATO
- Neo-eugenics
- Neurohacking
- Neurotechnology
- New Utopia
- New Zealand
- Nihilism
- Nootropics
- NSA
- Oceania
- Offshore
- Olympics
- Online Casino
- Online Gambling
- Pantheism
- Personal Empowerment
- Poker
- Political Correctness
- Politically Incorrect
- Polygamy
- Populism
- Post Human
- Post Humanism
- Posthuman
- Posthumanism
- Private Islands
- Progress
- Proud Boys
- Psoriasis
- Psychedelics
- Putin
- Quantum Computing
- Quantum Physics
- Rationalism
- Republican
- Resource Based Economy
- Robotics
- Rockall
- Ron Paul
- Roulette
- Russia
- Sealand
- Seasteading
- Second Amendment
- Second Amendment
- Seychelles
- Singularitarianism
- Singularity
- Socio-economic Collapse
- Space Exploration
- Space Station
- Space Travel
- Spacex
- Sports Betting
- Sportsbook
- Superintelligence
- Survivalism
- Talmud
- Technology
- Teilhard De Charden
- Terraforming Mars
- The Singularity
- Tms
- Tor Browser
- Trance
- Transhuman
- Transhuman News
- Transhumanism
- Transhumanist
- Transtopian
- Transtopianism
- Ukraine
- Uncategorized
- Vaping
- Victimless Crimes
- Virtual Reality
- Wage Slavery
- War On Drugs
- Waveland
- Ww3
- Yahoo
- Zeitgeist Movement
-
Prometheism
-
Forbidden Fruit
-
The Evolutionary Perspective
Category Archives: Evolution
The Evolution of Bikes at Red Bull Rampage: Two Decades of Progression – Red Bull
Posted: September 2, 2021 at 2:29 pm
The venue isnt the only thing that has changed over the last 20 years of RedBull Rampage. This awe-inspiring event has an illustrious reputation and has been tested by both man and machine since 2001. The event has evolved from a ragtag group of freeriders gathering in the desert with customized bikes, to a world-class event that hosts athletes who spend the entire year training for this one competition. Although the crowds and coverage have grown like the features that riders take on, much has remained the same here in the Utah desert. Great leaps have been made in bike design thanks to technological advances and more acceptance of this extreme style of riding. Riders can now tackle bigger obstacles at higher speeds, ride more safely, and have faith that things will stay spinning round when they touch back to Earth on the backside of these monstrous drops.
Kyle Strait, two-time RedBull Rampage winner.
Christian Pondella
Crashes still happen but riders are calculated thanks to better equipment.
Christian Pondella
The early years saw a wide array of unique suspension designs & technology.
Christian Pondella
The Trek Session has been piloted by some of the most talented riders
Christian Pondella
In the middle years downhill bikes were replaced with more trickable bikes
Christian Pondella
Early freeriders helped push the limits of what was possible in MTB.
Christian Pondella
Carson Storch knows his equipment will hold up to massive G-forces.
Garth Milan / RedBull Content Pool
Modern-day bikes are helping riders send it farther than imagined.
John Gibson / RedBull Content Pool
Trek bikes are on podiums of riders like Brandon Semenuk & Brett Rheeder.
Paris Gore/RedBull Content Pool
This image of Cedric Gracia shows how short and compact the frames were
Christian Pondella
When looking at bicycle technology and equipment improvements there are a few major areas that allow riders to go bigger and faster than ever before. We asked Kyle Strait, two-time winner and the only athlete to have competed in every RedBull Rampage since 2001 what the biggest changes in bike technology have been. Without hesitation Strait replied, Geometry and suspension.
When looking at a profile image of a bike, geometry is one of the most notable changes. When riders and engineers discuss bike geometry, or geo, theyre referring to the points, length between points, and angles of the frame. Two of the biggest geometrical gains in the last 20 years come at the front half of the bike. The head tube angle and reach. Reach is the intersection point measuring the distance from a vertical line drawn up from the center of the bottom bracket to the top center of the head tube. Twenty years ago, mountain bikes still pulled much of their sizing, geometry and dimensions from road or cross-country mountain bikes.
Frame numbers have changed in every dimension from front to back, but one of, if not the most important angles is the head tube angle. The head tube is the large front tube that the fork slides through, and they have gotten drastically slacker in the last 20 years. A slacker head tube angle gives the bike a longer wheelbase, slows down the steering and puts the front wheel out in front of the rider further. A welcome feeling when dropping vertical pitches or trying to make smooth turns at speed.
Since much of the geometry theory and design carried over from decades of road or cross-country bike experience, freeriders and downhillers were limited by the 67-degree head tube angles found on some bikes. Modern day bikes are often running head tube angles as slack as 62-63 degrees, which is a huge difference over the length of the fork.
As head tube angles got slacker and reach dimensions grew longer, riders found increased confidence and stability. This progression in stability and confidence have helped evolve the size of features and terrain thats possible to navigate at RedBull Rampage. Looking at a side-by-side of a bike from 2001 to 2021 and youll see a much longer bike overall, with very few overlapping points of contact.
The early freeriders helped push the limits of mountain bike development
Christian Pondella
Another major improvement in bike technology comes from the suspension. Bikes have gone from having six inches of poorly damped travel to over eight inches of highly tunable and compliant suspension. Like many of the bike brands you see in the early photo galleries from RedBull Rampage, suspension companies and trends have faded. Early RedBull Rampage athletes rode coil-sprung shocks, and many competed on inverted forks from brands like 5th Element and Avalanche. The trend has definitely changed and most athletes these days are seen on air shocks with Fox or Rock Shox equipment found under the majority of the riders.
04
2004: A portly Specialized Big Hit with a Marzocchi Monster T fork
Christian Pondella
Thanks to the last two decades of riders pushing the envelope, engineers have worked to do the same on the design front. Computer animated design programs, finite element analysis, and lots of other high-tech steps are used to develop and check strength, life cycles and durability of products. This has resulted in bikes getting lighter, stronger, and more reliable.
Back in the day it wasnt uncommon for an aluminum or chromoly downhill bike to weight over 50 pounds. Todays downhill bikes can be made from thinner aluminum or carbon fiber and easily hit 34 pounds. With 15 less pounds of mass underneath them, riders can now spin, flip and maneuver much easier than they could before.
The bikes look raw & industrial compared to the modern works of today
Christian Pondella
Working in unison with the frame improvements are a number of new industry standards that have helped components evolve to be much stronger and longer lasting. For example, early mountain bikes carried over axle standards from road and cross-country mountain bikes, which were ill-equipped for the demands of off-road riding. In 2001 many of the riders were on thinner axles that were also narrower at 135mm spacing. Todays axles go up to 20mm thick, while rear end axle spacing is 150mm or even 158mm on some bikes. This wider spacing allows hubs to be much stronger, with better triangulation for the spokes to help keep wheels spinning true despite huge side loads from landing 360s or massive whips.
Other components like tires, handlebars, and brakes have also seen massive gains. New rubber compounds and sidewall stiffness increases have helped improve traction and reduce the chances of flat tires while more powerful 4-piston brakes have replaced unreliable 2-piston brakes found on early 2000s bikes. Handlebars have also increased in thickness to 35mm from 31.8mm or 25.4mm thick bars originally found on mountain bikes. This means a more precise steering feel and the ability to run much wider bars for increased leverage and a more powerful riding position.
The result of all these changes is a completely different mountain bike that is leaps ahead of what early competitors took to the slopes of the first RedBull Rampage with. To some they may look just like another bike, but to the discerning eye these modern freeride machines share little with their predecessors beyond the two wheels that keep them rolling down the mountain. Changes in geometry, suspension technology and better components all work together to help these riders push the limits of what is possible on the worlds most demanding stage. Its impossible to talk about bike development and technology without acknowledging the limits early riders pushed on their modified and sometimes homemade freeride machines at the early RedBull Rampage events. They helped create a new discipline of riding, pushed bike development and entertained viewers around the world for two decades. Cheers to the riders and bikes of Rampage.
Go here to see the original:
The Evolution of Bikes at Red Bull Rampage: Two Decades of Progression - Red Bull
Posted in Evolution
Comments Off on The Evolution of Bikes at Red Bull Rampage: Two Decades of Progression – Red Bull
Evolution goes live in South Africa with SunBet – Yogonet International
Posted: at 2:29 pm
E
volution has gone live in South Africa with online gaming services for SunBet, the online betting arm of Sun International Hotel and Casino Group, announced the company on Wednesday.
The live casino content provider will power online live games for SunBet through an agreement with Bede Gaming. The SunBet online sportsbook, which now includes Evolutions online live dealer games, tables, and game shows, recently went live to players on desktop and mobile. Ezugi, Evolutions sister brand in the area of Live Casino, will see its offering going live in the coming weeks.
We are enormously excited by the potential of the SunBet partnership, said Dean Finder, CEO of Evolution Services SA. Our live dealer solutions are extremely complementary to the existing Sun International and SunBet offering, not only in terms of replicating the land-based gaming experience but also by extending and diversifying their existing and very strong online sports betting offering.
The agreement with Evolution gains SunBet full access to the Evolution and Ezugi live games portfolio, including Roulette, Blackjack, Baccarat, as well as new generation online live game shows such as Gonzos Treasure Hunt, Crazy Time and Lightning Roulette. Moreover, live Poker variants and First Person/RNG versions of key Evolution titles will also be available.
Nitesh Matai, General Manager Sports Betting at Sun International, said: In sports betting, SunBet is renowned for its astounding online betting experience across a whole range of sports, complete with sophisticated features such as action bets, over 100,000 live in-play events and cash out. The world-class Evolution and Ezugi online live dealer offering now takes our online service for our customers to another level.
Sun International is one of the largest land-based casino operators in South Africa, and its portfolio also includes five-star hotels and resorts, including Palace of the Lost City at Sun City. By having secured this partnership with Evolution, Sun International aims at extending its casino experience beyond land-based venues and regular operation times.
Perhaps most exciting of all is that it provides all the live exhilaration of a visit to a modern casino plus a new generation of incredibly entertaining live game shows that offer huge variety and choice, added Matai.
By launching Evolutions offering, land-based customers will be able to play at flexible times, even when they are unable to visit the physical casino in person, as well as enabling the casino operator full flexibility and the ability to maintain the customer relationship at times when venues have restricted opening due to South Africas Covid protocols and curfews, describes a press statement.
Link:
Evolution goes live in South Africa with SunBet - Yogonet International
Posted in Evolution
Comments Off on Evolution goes live in South Africa with SunBet – Yogonet International
Review of The Evolution of the Armed Forces of the United Arab Emirates – Middle East Forum
Posted: at 2:29 pm
by Athol YatesWarwick, U.K.: Helion and Co., 2020. 380 pp. $69.95, paper.
Reviewed by Sterling JensenUAE National Defense College | All views are those of the author.
Middle East QuarterlyFall 2021
https://www.meforum.org/62612/review-evolution-of-the-armed-forces-of-uae
Yates' timely book recounts the history, challenges, and internal dynamics of building the most competent and modern military in the Arab world. Long dependent on foreigners to underwrite their security, Gulf Arab countries are facing the hard reality that global powers, particularly the United States, are little interested in being security guarantors in a region where ethno-sectarianism shapes geopolitics. Yates, of Khalifa University, Abu Dhabi, argues that the United Arab Emirates' (UAE) armed forces have set a different course, helping the country steer in a more favorable direction.
The book has three parts: the physical, cultural, and political environment of the UAE military; its defining characteristics; and the evolution of each main force (army, navy, air force). Yates details how the UAE's federation was built on compromise, cunningness, and cooptation, and how this history has shaped the armed forces. The various rulers moved from developing their own armed forces for defending local interests to creating a unified and integrated military for the wider national interest. The second and third sections provide a descriptive and well-researched overview of the forces' core missions and institutional histories. The book concludes with an assessment of the UAE armed forces' effectiveness and discusses the cultural challenges facing Arab militaries.
The book's main strength is that it does not shy away from the region's taboos, such as the history of distrust among the different emirates, challenges to federation, and an objective assessment of operational successes and failures. Discussing these issues makes the accomplishments of the UAE military more credible and convincing.
What is missing, however, is a more satisfying analysis of the sustainability of the UAE armed forces' progress. What helped the UAE armed forces become what they are today does not guarantee that their success will continue. The author assumes that the UAE military will advance as long as the country's enlightened leadership remains militarily savvy, is willing to spend big, and continues to wield a heavy hand in shaping the military's institutional culture. While the author points out that military culture must be aligned with national culture in order for it to sustain success, he does not assess whether that is likely to happen.
Despite this blind spot, the book is a deeply-researched and courageous attempt to give a transparent assessment and objective history of one of the most consequential and successful modern Arab militaries.
Related Topics: Persian Gulf & Yemen | Sterling Jensen | Fall 2021 MEQreceive the latest by email: subscribe to the free mef mailing listThis text may be reposted or forwarded so long as it is presented as an integral whole with complete and accurate information provided about its author, date, place of publication, and original URL.
See the original post:
Review of The Evolution of the Armed Forces of the United Arab Emirates - Middle East Forum
Posted in Evolution
Comments Off on Review of The Evolution of the Armed Forces of the United Arab Emirates – Middle East Forum
Public Health Watch: Tracing the Evolution of COVID-19 Treatment in Hospitalized Patients – Contagionlive.com
Posted: at 2:29 pm
The treatment for any disease constantly evolvesparticularly when the disease in question is caused by an emerging pathogen.
Unfortunately, skeptics continue to use the changing science around the treatment (as well as the prevention and spread) of COVID-19 as evidence that it is somehow not up to snuff. Nothing could be further from the truth, in most cases, at least when it comes to caring for patients with severe disease.
On that score, although there is still no cure for the disease caused by SARS-CoV-2, there are treatments that do provide some relief.
In a study published on August 17 by Annals of Internal Medicine, researchers from across the country have attempted to chronicle the narrative arcfor lack of a better phraseof COVID-19 care. The Cliffs Notes version (forgive the data reference): The story starts with hydroxychloroquine, continues through remdesivir, and ends (at least for now) with dexamethasone and some cautious optimism.
Earlier in the pandemic, patients and clinicians were desperately looking for COVID-19 treatment, Hemalkumar B. Mehta, PhD, an assistant professor of epidemiology at the Johns Hopkins Bloomberg School of Public Health in Baltimore, told Contagion. Unfortunately, the use of hydroxychloroquine was based on weak scientific evidence [and] media coverage and hype increased public interest in hydroxychloroquine. As soon as the scientific evidence showed no benefits and possible harms of hydroxychloroquine, clinicians stopped using it. The case of hydroxychloroquine provides a good reminder that solid scientific evidence should be a major driver for COVID-19 treatment.
Over the course of the study period, February 1, 2020 through February 28, 2021, among 137,870 people hospitalized with confirmed or suspected COVID-19, 8754 (6.3%) received hydroxychloroquine. However, use of the drug increased during March 2020, peaking at 42%, and started to drop by April 2020, as new data emerged demonstrating that it offered little, if any clinical benefit. By February of this year, just 0.6% of hospitalized COVID-19 patients were given the drug.
Conversely, 29,272 (21.2%) of the study patients were given remdesivir and 53,909 (39.1%) were administered dexamethasone over the 13-month study period, gradually increasing throughout. Indeed, following release of results from the RECOVERY (Randomised Evaluation of COVID-19 Therapy) trial in mid-June, 78% to 84% of patients on invasive mechanical ventilation received dexamethasone or another glucocorticoid, the researchers found. Remdesivir use peaked at 27% in February.
However, even this increased use might not have been sufficient. Of the patients who may have benefited from dexamethasone, for example, approximately 1 in 5 patients did not receive the steroid, according to Dr. Mehta. Its use peaked at 53% of potentially eligible patients in November 2020 and stood at 33% in February, but these figures vary substantially across health centers (intraclass correlation coefficient, 14.2%).
We found that remdesivir and dexamethasone were used variably across health systems [and] we need to ensure that these drugs are given to the right patients and used consistently to improve outcomes among patients hospitalized with COVID-19, Mehta said. For example, there is compelling evidence that dexamethasone is beneficial to those with COVID who are hospitalized and require supplemental oxygen. Because the pandemic is still ongoing, we must continue to generate scientific evidence on COVID-19 treatment to help patients and clinicians select appropriate drug therapies.
Go here to read the rest:
Posted in Evolution
Comments Off on Public Health Watch: Tracing the Evolution of COVID-19 Treatment in Hospitalized Patients – Contagionlive.com
400-Million-Year-Old Fossils Reveal How the First Roots Evolved – SciTechDaily
Posted: at 2:29 pm
New research demonstrates how the oldest known root axed developed more than 400 million years ago. The evolution of roots at this time was a dramatic event that impacted our planet and atmosphere and resulted in transformative ecological and climate change.
The first evidence-based 3D reconstruction of the fossil Asteroxylon mackiei, the most structurally complex plant from the Rhynie chert has shown how roots and other types of axes developed in this ancient plant. The fossil is preserved in chert (a type of flint) found near village of Rhynie in Aberdeenshire, Scotland. The specimens are exceptionally well-preserved in the 407-million-year-old rocks from the Early Devonian period.
The extinct genus Asteroxylon belongs to the group of plants called the lycophytes, a class that also comprises living representatives such as isoetes and selaginella. The reconstruction has allowed researchers, for the first time, to glean both anatomical and developmental information of this mysterious fossil. This is of particular significance because previous interpretations of the structure of this fossil plant were based to a large extent on comparisons of fragmentary images with extant plants.
Thin slice of the 407 million-year-old Rhynie chert mounted on a glass slide showing the amazing preservation of fossil plants preserved within. Specimen number 4178 in the paleobotanical collection at the University of Mnster, Germany. Each interval on the scale bar is 1 mm. Credit: Sandy Hetherington
The reconstruction demonstrates that these plants developed roots in an entirely different way than extant plants develop roots today. The rooting axes of A. mackiei are the earliest known types of plant roots.
These are the oldest known structures that resemble modern roots and now we know how they formed. They developed when a shoot-like axis formed a fork where one prong maintained its shoot identity and the second developed root identity, says Dolan. This mechanism of branching, called dichotomous branching, is known in living plants within tissues that share structural identity. However, as Dolan stresses: No roots develop in this way in living plants, demonstrating that this mechanism of root formation is now extinct. Their findings demonstrate how a now extinct rooting system developed during the evolution of the first complex land plant.
View over the village of Rhynie in Aberdeenshire, Scotland. The fossil deposit known as the Rhynie chert is named after the village of Rhynie were it was first discovered just over a century ago. Credit: Sandy Hetherington
100 Years after the discovery of the fossils in Rhynie, our reconstruction demonstrates what these enigmatic plants really looked like! The reconstruction also demonstrates how the roots formed exclaims GMI group leader Liam Dolan, co-corresponding author on the work. Understanding the structure and evolution of these plants from the Early Devonian period provides us with an insight into events at a key time in Earth history just after plants colonized the dry surfaces of the continents as they began to spread radiate across the land.
Their evolution, radiation, and spread across all continents had a dramatic impact on the Earth system. Plant roots reduced atmospheric CO2 levels, stabilized the soil and revolutionized water circulation across the surfaces of continents, states first author and co-corresponding author Alexander (Sandy) J. Hetherington, group leader at the University of Edinburgh. At the root of the environmental and ecological impact of plant evolution are the plant roots themselves!
Hetherington highlighted how his research was enabled by fossils that were collected by generations of paleontologists that are housed in many different museums and universities. The answers to so many of the key questions of evolution are lying in shelves in these institutions said the scientist who is now based at the University of Edinburgh. Using digital 3D techniques it is possible for the first time to visualize the complex body plan of A. mackiei allowing us to discover how these enigmatic plants developed. It was brilliant to finally see details that had previously been hidden.
Reference: An evidence-based 3D reconstruction of Asteroxylon mackiei, the most complex plant preserved from the Rhynie chert by Alexander J Hetherington, Siobhn L Bridson, Anna Lee Jones, Hagen Hass, Hans Kerp and Liam Dolan, 24 August 2021, eLife.DOI: 10.7554/eLife.69447
Continue reading here:
400-Million-Year-Old Fossils Reveal How the First Roots Evolved - SciTechDaily
Posted in Evolution
Comments Off on 400-Million-Year-Old Fossils Reveal How the First Roots Evolved – SciTechDaily
Evolution of the probiotics from common food to targeted bacteriotherapy – Express Healthcare
Posted: at 2:29 pm
Referring to the quality of probiotic products, Kanwaldeep Singh, founder and chief executive, Next Gen Pharma highlights that despite significant advances in understanding the potential uses and health benefits of some probiotic strains, clinicians, researchers, and consumers remain unclear by the probiotic umbrella concept heavily promoted by the probiotic/pharmaceutical industry
The market for probiotics is growing exponentially foods, dietary supplements, and drugs- for the well-being of people ranging from health conscious to those that need a treatment for disease conditions. Probiotics have come a long way, from being considered as an adjuvant to an independent therapy, with proven efficacies in treating difficult to treat chronic conditions or orphan disease conditions and thus addressing some of the Unmet needs. Take for example a proprietary mix referred to as SLAB-51 has shown promising evidence in reducing the progression of the dieses and mortality among moderate to serious COVID-19 patients. Likewise, another probiotic containing Lactobacillus brevis CD2, available under the brand Mucofan, has been proven to prevent Chemo-radiotherapy induced Oral Mucositis, a difficult to treat condition which impairs the ability to eat/chew among cancer patients, and may result in cessation of therapy.
Regulation of probiotics varies from region to region, resulting in a heterogeneous regulatory framework. Probiotics are regulated as dietary supplements unless they make disease-specific health claims, and regulation focuses on the legality of each claim based on efficacy, safety, and quality. Probiotics can also be classified as medical foods when prescribed for the dietary management of diseases needing a distinctive nutritional profile not met by a regular diet alone. A probiotic product can be classified as a medical food only if supported by high-quality clinical trials. In some countries including India, Russia etc. select Probiotics have been also registered as drugs and have been approved to treat or prevent disease conditions based on the evidence provided by clinical trials.
Despite significant advances in understanding the potential uses and health benefits of some probiotic strains, clinicians, researchers, and consumers remain unclear by the probiotic umbrella concept heavily promoted by the probiotic/pharmaceutical industry. The umbrella concept extends the benefits obtained with a particular formulation to other probiotic products. All the information regarding the product specificity, dosage, duration of administration, combination of strains, and methods used to prepare the original studied formulations are often ignored and at times seems like willful neglect. Manufacturing processes, conditions, and ingredients are crucial to product performance. Even for established brands/products, changes in manufacturing location may result in a product that is not identical to the original in terms of efficacy and safety unless appropriate measures and controls are taken. Since many probiotics properties are strain-specific, safety and efficacy results for specific products should not be generalized to other probiotics. Unfortunately, current trademark law and the lack of strict regulation of probiotics means that brand owners may sell any product under the same brand name, even if the new product differs significantly from the original one previously studied for safety and efficacy.
For example, In the USA, on July 23, 2019, a group of patients filed a class-action lawsuit against the sellers of the VSL#3 product manufactured by Actial/ VSL Pharmaceuticals Inc. The class action alleges that Actial/VSL developed a new VSL#3 product different from the original one. The suit alleges that the new VSL#3 is different from the formulation sold under the same trademark VSL#3 until 2016. Consumers are seeking hundreds of millions of dollars in damages. In the USA, the Federal Court since June 2019 has entered a permanent injunction against the current and former distributors of VSL#3 to stop their false advertising. The product is available in India, under the same brand VSL#3! Locally in India, a recent study published in November 2020 by an independent team of investigators from Chennai analyzed 20 most commonly available brands of probiotics and found poor correlation between the declared content on the pack and the lab results from their analysis. The regulatory loopholes thus exploited have severe implications for patients when probiotics are used as part of a treatment recommended in clinical guidelines for painful conditions such as inflammatory bowel disease, liver diseases, juvenile autoimmune diseases, etc. This leads to a very important question! Should Indian Authorities intervene? It is important for doctors to note that they become responsible for prescribing a product whose safety, efficacy and consistency of quality have not been tested and this can have serious implications, both in terms of the risk to patients and the related legal consequences. In this context, controlling probiotic products is mandatory to determine their authenticity and ensure consistency with manufacturers claims. Unfortunately, genomic analysis alone is not sufficient to characterize the complexity of probiotics. Genetically identical strains grown under different conditions or different culture methods have other phenotypic characteristics, such as viability, enzymatic activity, and compound metabolism. Until a few years ago, doctors and authorities did not realize the need to develop a method to verify the authenticity of probiotic products.
Probiotics represent a major opportunity in healthcare for patients and the industry alike. The sooner we have a robust, working regulatory framework suited to the Indian context, the better it will be for everyone. Given the recent focus on healthcare, a rapid response to this priority is the need of the hour.
Go here to see the original:
Evolution of the probiotics from common food to targeted bacteriotherapy - Express Healthcare
Posted in Evolution
Comments Off on Evolution of the probiotics from common food to targeted bacteriotherapy – Express Healthcare
Watch The Fascinating Evolution Of The Batmobile – CarBuzz
Posted: at 2:29 pm
Next up is the Batmobile of 2005, otherwise known as "The Tumbler". In this design, we see that the Batmobile has evolved from a symbol of humanity and hope into an obsessive, vengeful, angry, purpose-driven machine of war - just like the character that drives it. All that matters is being invulnerable and shutting out anything that can hurt or harm the person or the car. As Stephenson notes, this could be the villain's car, and the line between good and evil is extremely blurred. And as the Joker says, "people are only as good as you allow them to be."
Finally, we get to the upcoming Batmobile that we've only seen some teasers of. Things will get even darker, with a dystopian flavor that implies pain, struggle, and a general lack of hope. Ultimately, as Stephenson notes throughout, each Batmobile symbolizes the era in which it debuted on the silver screen. If Batman films are indeed a social commentary, the future is going to be a very scary place...
Read more from the original source:
Posted in Evolution
Comments Off on Watch The Fascinating Evolution Of The Batmobile – CarBuzz
Data Evolution: Harnessing Intelligent Data to Improve the Customer Experience & Uncover Growth Opportunities – Banking Exchange
Posted: at 2:29 pm
Its undeniable that the pace of digital transformation has accelerated. The pandemic sped up the creation and adoption of digital platforms across a number of industries, including financial services.
More than ever, banking customers are using mobile apps and online platforms to handle financial transactions. This increased use of digital tools has created a wealth of valuable data that financial institutions can leverage to pursue customer intelligence initiatives, but only if the right next-generation banking solutions are in place.
Taking Advantage of Customer Intelligence
Customer intelligence involves the gathering and analyzing of customer data to get a better understanding of their behaviors and activities in order to strengthen customer relationships, provide greater customer value and enable data-driven decision making. For banks, customer intelligence can be an incredibly valuable predictor of growth and profitability, especially given increased adoption of digital service channels and the untapped data sources that go along with it.
However, deriving key data insights to better understand evolving customer needs and respond to them with precision, speed and efficiency requires intelligent data solutions.
Leveraging the Right Tools to Deliver Smart Data
By using next-generation banking solutions, financial institutions can glean meaningful data to learn what their customers value most, and better determine how to give them what they want. This not only benefits the customer by improving their experience, but benefits the organization by helping to attract and retain customers while increasing revenue.
According to McKinsey, A survey of US retail banking customers found that at the banks with the highest degree of reported customer satisfaction, deposits grew 84% faster than at the banks with the lowest satisfaction ratings. In addition, Research shows that the stronger the experience and the more satisfied the customer, the more likely it is that the bank will generate higher revenue: a more satisfied customer typically accounts for approximately 2.4 times more revenue than a neutral customer.
This is where harnessing intelligent data comes in. With the right technology in place, banks can assess transaction data in real time to deliver personalized insights to customers and uncover upsell and cross-sell opportunities for new products and services based on customer actions. In this way, data takes the burden off the customer when it comes to figuring out how to navigate a digital banking app or determine what next steps to take. An easy and intuitive experience equals a positive one.
But, before useful data aggregation can occur and actionable insights can be realized, financial institutions must overcome two pervasive issues: integration of legacy systems and breaking down silos.
This takes a solution that can, in effect, stitches different experiences together, from front-end user interfaces to back-end data applications. Many financial institutions use an array of digital platforms and databases that arent necessarily aware of each other or able to communicate with one another. With the right solution in place, legacy systems can seamlessly share information and overcome fragmentation by aggregating siloed dataso that all an end user ever realizes is a great, engaging experience.
5 Ways Intelligent Data Can Improve the Customer Experience
Bank customers have come to expect relevant, personalized digital experiences that match their digital experiences in other aspects of life. A financial institution that deeply understands their needs will win out over one that offers generic, cookie-cutter experiences.
For a financial institution to grow and thrive in modern times, it must cater to the customer experience. Here are 5 ways the use of intelligent data can inform customer offerings.
Final Thoughts
Leveraging customer intelligence and smart data can help financial institutions foster greater connections with customers and create a more meaningful, thoughtful experience. But as banks make the move to invest in technology that makes this possible, its important to remember to be deliberate in how its rolled out.
Many financial institutions have data that goes back decades, and not all of it is useful. It might be repetitive, incorrect or simply outdated. Its best to ensure only quality data is used. Its also crucial to achieve multiple integrations via varying data sources. This includes data generated via chat or with a voice assistant, and even via social media, in addition to CRM systems and credit systems. But, to get there, start by mining just one data set and widening the net from there. It will help to cut down on errors while simplifying the data aggregation process.
Achieving data aggregation is where banks need to be. To set the stage for future growth and success, financial institutions must embrace data and analytics to transform the business in a way that exceeds evolving customer expectations. That will require a digital makeover across all touchpoints within the organization.
By Marc Jones, CTO, Alkami
More:
Posted in Evolution
Comments Off on Data Evolution: Harnessing Intelligent Data to Improve the Customer Experience & Uncover Growth Opportunities – Banking Exchange
Mitch Gould and Nutritional Products International Celebrate 15th Anniversary of ‘Evolution of Distribution’ – PRNewswire
Posted: at 2:29 pm
BOCA RATON, Fla., Aug. 30, 2021 /PRNewswire/ --Mitch Gould developed the "Evolution of Distribution" platform in 2008, just a few years after Facebook started and YouTube was still in its infancy.
"A lot has changed in the past 15 years," said Gould, CEO of Nutritional Products International in Boca Raton, FL. "I have watched retail and consumer buying trends carefully, which is why I recently enhanced my 'Evolution of Distribution' platform to coincide with its 15th anniversary."
The "Evolution of Distribution" platform is a one-stop, turnkey operation for companies that want to launch new health and wellness products in the U.S.
"We import, distribute, and promote through a turnkey one-stop solution in the largest marketplace in the world," Gould added.
NPI brings together the services companies need to successfully launch products with the "Evolution of Distribution" platform.
"NPI becomes their U.S. headquarters. NPI's team becomes their staff," Gould said. "I have salespeople, support staff, operations manager, regulatory guidance officer, and a marketing team working together on behalf of NPI's clients.
"I am proud that NPI's executive team has retail professionals who have worked for major retailers in the country, such as Amazon, Walmart, and Glanbia Performance Nutrition, the largest sports nutrition company in the world."
Gould said NPI emphasizes cost efficiency and speed to market.
However, the "Evolution of Distribution" platform had to adapt to keep up with the changing trends.
"Because of the rapid acceleration of online shopping during the pandemic, NPI in 2020 increased its emphasis on e-commerce and just recently added TV marketing to its promotions."
NPI adapted because the pandemic and technology have changed consumer buying habits forever.
"The convergence of the internet and smartphone technology kick-started the online e-commerce industry," Gould said. "Then you had the vision of Jeff Bezos, who decided to sell everything online."
In the early 2000s, Amazon launched its health and wellness category.
"I heard about Amazon's new category and realized I had the contacts to place major health and wellness sports nutrition brands with the soon-to-be online giant," he said.
"The internet, smartphones, and Bezos have changed the retail sector," he added. "There is no going back."
For more information, visitnutricompany.com.
MORE ON NPI AND ITS FOUNDER
NPI is a privately-held company that specializes in the retail distribution of nutraceuticals, dietary supplements, functional beverages, and skin-care products. NPI offers a unique, proven approach for product manufacturers worldwide seeking to launch or expand the distribution of their products in the U.S. retail market.
Mitch Gould, the founder of NPI, is a third-generation retail distribution and manufacturing professional. Gould, known as a global marketing guru, has represented icons from the sports and entertainment worlds such as Steven Seagal, Hulk Hogans, Ronnie Coleman, Roberto Clemente Jr., Chuck Liddell, Wayne Gretzky.
Media Contact:
Andrew Polin561-421-3045[emailprotected]
SOURCE Nutritional Products International
Continue reading here:
Posted in Evolution
Comments Off on Mitch Gould and Nutritional Products International Celebrate 15th Anniversary of ‘Evolution of Distribution’ – PRNewswire
Evolution Deniers Are Finally a Minority in the U.S. – Gizmodo
Posted: August 20, 2021 at 5:47 pm
A skull on display as part of the Neanderthal exhibition at the Musee de lHomme in Paris on March 26, 2018. Photo: STEPHANE DE SAKUTIN/AFP (Getty Images)
Americans continue to have a challenging relationship with science, modern medicine, and at times reality, but a review of annual surveys from 1985 to 2019 does yield some good news: Over half of surveyed participants believed in the science of evolution. Thats a win, I guess.
Nearly a century ago, the Scopes trial of 1925 pitted a science teacher and his curriculum (which included evolutionary theory) against the state of Tennessee, which had just banned the subject in schools because, they said, it contradicted the Bibles creation story. Evolutionary theory is the idea that living organisms change over time, adapting to their environments through a process called natural selection. The naturalist Charles Darwin observed and chronicled such adaptations in the beaks of finches in the Galapagos Islands. Like every other living thing, humans have evolved over time, and its that fact that certain folks seem to take the most issue with.
Over the decades, more and more Americans have accepted evolution by natural selection as a driving force of life on Earth. For a long time, though, the split was pretty much half-and-half, but a new study from the University of Michigan has found that the deniers are finally in the minority. The paperpublished this week in the journal Public Understanding of Sciencelooked at opinions on evolution in public opinion surveys conducted since 1985. It found that a recent surge has pushed Americans over the halfway line in believing in the theory put forth by Darwin in his 1859 book On the Origin of Species.
Anti-evolution books being sold in Dayton, Tennessee, where the Scopes trial happened.Photo: Topical Press Agency (Getty Images)
From 1985 to 2010, there was a statistical dead heat between acceptance and rejection of evolution, said Jon D. Miller, a researcher who specializes in public understanding of science at the Institute for Social Research at the University of Michigan and lead author of the paper, in a university press release. But acceptance then surged, becoming the majority position in 2016.
G/O Media may get a commission
The surveys analyzed by the team were conducted by the National Science Board, NASA, and subsidiaries of the National Science Foundation, which posed the following statement to American adults to agree or disagree with: Human beings, as we know them today, developed from earlier species of animals. For the first 20 years of the study, the yes-and-no results were pretty even. Not so anymore: 54% of survey participants agreed with the statement in 2019.
In a time filled with disinformation, distrust of expertise, and utter foolishness, some folks previously not keen on the idea of evolution have decided its not so bad. Maybe its because denialists have moved on to hotter topics like covid-19 and climate change. Evolution is just old hat, perhaps.
Though the number of participants who identified as religious fundamentalists declined in the last decade, the research team found that even those individuals have started to come around. In 1988, only 8% of self-described fundamentalists accepted evolution; in 2019, the number was 32%.
Co-author Mark Ackerman noted that more than twice as many Americans had college degrees in 2018 than in 1988; while that may play a role, the more clear-cut connection is political. In 2019, the most recent year included in the work, only 34% of people who identified as conservative Republican said they accepted evolution, while 83% of people who identified as liberal democrats said the same.
More: Pope Rails Against Intelligent Design, Says God Isnt A Magician
Read more:
Evolution Deniers Are Finally a Minority in the U.S. - Gizmodo
Posted in Evolution
Comments Off on Evolution Deniers Are Finally a Minority in the U.S. – Gizmodo