Category Archives: Cf

Dividend paying stocks like CF Industries Holdings, Inc. (NYSE:CF) tend to be popular with investors, and for good reason some research suggests a significant amount of all stock market returns come from reinvested dividends. If you are hoping to live on your dividends, its important to be more stringent with your investments than the average punter. Regular readers know we like to apply the same approach to each dividend stock, and we hope youll find our analysis useful.

A 2.5% yield is nothing to get excited about, but investors probably think the long payment history suggests CF Industries Holdings has some staying power. The company also returned around 6.3% of its market capitalisation to shareholders in the form of stock buybacks over the past year. Some simple analysis can offer a lot of insights when buying a company for its dividend, and well go through this below.

Click the interactive chart for our full dividend analysis

Companies (usually) pay dividends out of their earnings. If a company is paying more than it earns, the dividend might have to be cut. Comparing dividend payments to a companys net profit after tax is a simple way of reality-checking whether a dividend is sustainable. CF Industries Holdings paid out 60% of its profit as dividends, over the trailing twelve month period. This is a healthy payout ratio, and while it does limit the amount of earnings that can be reinvested in the business, there is also some room to lift the payout ratio over time.

We also measure dividends paid against a companys levered free cash flow, to see if enough cash was generated to cover the dividend. CF Industries Holdingss cash payout ratio last year was 24%, which is quite low and suggests that the dividend was thoroughly covered by cash flow. Its encouraging to see that the dividend is covered by both profit and cash flow. This generally suggests the dividend is sustainable, as long as earnings dont drop precipitously.

As CF Industries Holdings has a meaningful amount of debt, we need to check its balance sheet to see if the company might have debt risks. A rough way to check this is with these two simple ratios: a) net debt divided by EBITDA (earnings before interest, tax, depreciation and amortisation), and b) net interest cover. Net debt to EBITDA measures total debt load relative to company earnings (lower = less debt), while net interest cover measures the ability to pay interest on the debt (higher = greater ability to pay interest costs). CF Industries Holdings has net debt of 2.13 times its EBITDA. Using debt can accelerate business growth, but also increases the risks.

We calculated its interest cover by measuring its earnings before interest and tax (EBIT), and dividing this by the companys net interest expense. With EBIT of 4.07 times its interest expense, CF Industries Holdingss interest cover is starting to look a bit thin.

Before buying a stock for its income, we want to see if the dividends have been stable in the past, and if the company has a track record of maintaining its dividend. For the purpose of this article, we only scrutinise the last decade of CF Industries Holdingss dividend payments. The dividend has been stable over the past 10 years, which is great. We think this could suggest some resilience to the business and its dividends. During the past ten-year period, the first annual payment was US$0.08 in 2009, compared to US$1.20 last year. Dividends per share have grown at approximately 31% per year over this time.

Its rare to find a company that has grown its dividends rapidly over ten years and not had any notable cuts, but CF Industries Holdings has done it, which we really like.

While dividend payments have been relatively reliable, it would also be nice if earnings per share (EPS) were growing, as this is essential to maintaining the dividends purchasing power over the long term. Over the past five years, it looks as though CF Industries Holdingss EPS have declined at around 17% a year. A sharp decline in earnings per share is not great from from a dividend perspective, as even conservative payout ratios can come under pressure if earnings fall far enough.

To summarise, shareholders should always check that CF Industries Holdingss dividends are affordable, that its dividend payments are relatively stable, and that it has decent prospects for growing its earnings and dividend. First, we think CF Industries Holdings has an acceptable payout ratio and its dividend is well covered by cashflow. Its not great to see earnings per share shrinking. The dividends have been relatively consistent, but we wonder for how much longer this will be true. In sum, we find it hard to get excited about CF Industries Holdings from a dividend perspective. Its not that we think its a bad business; just that there are other companies that perform better on these criteria.

Given that earnings are not growing, the dividend does not look nearly so attractive. Businesses can change though, and we think it would make sense to see what analysts are forecasting for the company.

Looking for more high-yielding dividend ideas? Try our curated list of dividend stocks with a yield above 3%.

We aim to bring you long-term focused research analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material.

If you spot an error that warrants correction, please contact the editor at editorial-team@simplywallst.com. This article by Simply Wall St is general in nature. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. Simply Wall St has no position in the stocks mentioned. Thank you for reading.

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Would CF Industries Holdings, Inc. (NYSE:CF) Be Valuable To Income Investors? - Simply Wall St

Zooming in on shares of CF Industries Holdings, Inc. (NYSE:CF), we note that the average target price is presently $54.75. This is the consensus target based on projections provided by the covering analysts polled. Wall Street analysts have the ability to provide price target predictions for stocks that they cover. Price target estimates can be calculated using various methods. Many investors will track stock target prices, especially when analysts make changes to the projections. A good research report will generally give detailed reasoning for a specific target price estimate. Some investors may follow analyst targets very closely and use the information to complement their own stock research.

Trading the stock market can sometimes feel like a wild roller coaster ride. When stocks are soaring, investors may feel like they cant lose. When markets are sinking, investors may feel like there is nothing that they can do. Individual investors may have experienced both ends of the spectrum. Sometimes, an investor may secure some winning trades right out of the gate. This may cause the individual to become overconfident in their ability. Markets have the ability to shoot down overconfidence very quickly. On the other side, investors may only experience losses right off the bat and become highly discouraged. Figuring out how to manage winners and losers can big a big help to the investors psyche in the long-term. Frequently assessing which trades worked and examining why they worked may greatly assist the investor. The same can be said for trades that did not pan out.

Checking in on stock price activity for CF Industries Holdings, Inc. (NYSE:CF), we have recently seen shares trading near the $48.65 mark. Investors will often track the current stock price in relation to its 52-week high and low levels. The 52-week high is currently $56.06, and the 52-week low is presently $39.01. When the current stock price is trading close to either the 52-week high or 52-week low, investors may pay closer attention to see if there will be a breakthrough that level. Over the past 12 weeks, the stock has seen a change of 4.31%. Going back to the start of the calendar year, we can see that shares have moved 11.81%. Pulling the focus closer to the past 4 weeks, shares have seen a change of .81%. Over the past 5 trading days, the stock has moved -2.72%.

Taking a quick look at analyst opinions, we can see that the current average broker recommendation on shares of CF Industries Holdings, Inc. (NYSE:CF) is presently 2.11. Out of the covering analysts polled by Zacks Research, 4 have put a Strong Buy or Buy rating on the stock.

As earnings season comes into focus, investors will be closely tracking sell-side estimates. According to analysts polled by Zacks Research, the current quarter EPS consensus estimate is currently sitting at .34 for shares of CF Industries Holdings, Inc. (NYSE:CF). The number consists of estimates provided by 5 contributing analysts. For the last reporting period, the company posted a quarterly EPS of 1.28. The consensus estimate for last quarter before the earnings report was .81. Looking out further to the next quarter EPS estimate, the consensus is currently resting at .49. This consensus estimate includes 3 analysts taken into consideration by Zacks. Shifting the focus to the current fiscal year EPS estimate, the number is currently 1.48. Widening the gaze to the next fiscal year, we can see that the consensus EPS estimate is presently 2.29.

Active traders are typically striving to spot winning entry and exit points for trades. Following technical indicators may help traders gain some insight on how best to do this. There are plenty of indicators that have helped traders make winning trades. Because there are so many to choose from, beginning traders may want to start by focusing on a few different combinations to start with. Professional chartists may have ultra complex charts set up to spot perfect trade entries. Others may use one or two simple indicators to aide with setting up the trade. Keeping track of all the data may be a challenge at first, but there are many platforms out there that have made the process much simpler than ever before. Setting up a winning strategy may take some time and perseverance, but taking the time to acquire the proper knowledge may mean the difference between winning and losing trades in the future.

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Watching the Consensus Target Price on These Shares: CF Industries Holdings, Inc. (NYSE:CF) - Blackwell Bulletin

The lung clearance index (LCI) is more sensitive to changes in lung function in patients with mild cystic fibrosis (CF) than conventional spirometry parameters, a study asserts.

The findings were reported in the study, Lung clearance index to detect the efficacy of Aztreonam lysine inhalation in patients with cystic fibrosis and near normal spirometry A single-centre feasibility study, published recently in the journalPLOS One.

The first clinical trials evaluating the effectiveness of inhaled antibiotics in patients with moderate or severe CF have used spirometry parameters, such as forced expiratory volume in one second (FEV1, the total amount of air a patient is able to exhale in one second after taking a deep breath), as a readout of lung function.

Previous studies showed thatGilead Sciences Cayston (aztreonam lysine), an inhaled antibiotic often used to treat infections caused by the bacteria Pseudomonas aeruginosa in CF patients, was found to be superior to tobramycin, another antibiotic normally prescribed to patients who develop P. aeruginosa lung infections.

However,many patients have normal or near normal FEV1despite chronicP.aeruginosa infection, the researchers wrote. In addition, when working with small patient groups it is difficult to detect changes after treatment using FEV1 as an endpoint [goal], they added.

For that reason, scientists have been looking for alternative readouts that would be more sensitive than FEV1, and better suited to evaluate lung function in patients with milder forms of CF who have chronic lung infections caused by P. aeruginosa.

At the CF Centre Innsbruck, we have been using the multiple breath washout (MBW) technique for many years to measure lung clearance index (LCI). Abnormal LCI is associated with early structural lung disease detectable by high resolution computerized tomography (HRCT) scans when FEV1 may still be normal, the investigators wrote.

In the study, researchers reported the findings of an observational, open-label trial (2013-004295-35), in which the effects of several inhaled anti-pseudomonal antibiotics in patients with mild CF were assessed using the standard FEV1 and LCI parameters.

The study was divided into two treatment phases: in phase 1 (weeks 0-8), patients received standard treatment with inhaled tobramycin, using either TOBI (300 mg/5 ml, twice a day), or TOBI Podhaler (112 mg, twice a day). In phase 2 (weeks 8-16), patients received treatment with Cayston (75 mg, three times a day).

The study enrolled a total of eight CF patients between the ages of 15-49 (median age of 28 years), who had chronic lung infections caused by P. aeruginosa for more than six years, and had been taking inhaled anti-pseudomonal antibiotics for approximately four years.

At baseline, FEV1 ranged between 76.3% and 123.8%, with a median of 87%, which is considered normal or near normal. (FEV1 lower than 75% is indicative of lung function impairment.)

At baseline, LCI values ranged between 6.4 and 11.4, with a median of 8.59, which is above the upper limit of a normal range (7.0), indicating the presence of lung disease.

After four weeks of treatment with Cayston, LCI values decreased in seven of the eight patients participating in the study. Conversely, while receiving standard treatment with tobramycin, only half of the patients (four patients) experienced a significant improvement in LCI values.

No significant differences were found in FEV1 values while patients were receiving standard treatment with tobramycin, or afterward with Cayston.

Respiratory symptoms showed clinically important improvements after AZLI [Cayston] treatment (median change +8.5), and better results than after tobramycin (median -3.0). Treatments were well tolerated, and no adverse events were reported, researchers wrote.

Based on the results regarding the two lung function parameters tested, the team believes lung clearance index can be used to detect treatment induced changes in subjects with mild lung disease, and should be considered as a clinical endpoint for trials.

In line with their results, the team noted thatexpert committees have previously stated LCI is a valuable potential outcome parameter in patients with normal FEV1, since LCI can detect treatment differences even in small patient groups, they wrote.

Joana holds a MSc in Biology and a MSc in Evolutionary and Developmental Biology from Universidade de Lisboa. She is currently finishing her PhD in Biomedicine and Clinical Research at Universidade de Lisboa. Her work has been focused on the impact of non-canonical Wnt signaling in the collective behavior of endothelial cells cells that made up the lining of blood vessels found in the umbilical cord of newborns.

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Patrcia holds her PhD in Medical Microbiology and Infectious Diseases from the Leiden University Medical Center in Leiden, The Netherlands. She has studied Applied Biology at Universidade do Minho and was a postdoctoral research fellow at Instituto de Medicina Molecular in Lisbon, Portugal. Her work has been focused on molecular genetic traits of infectious agents such as viruses and parasites.

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LCI More Sensitive Than FEV1 in Patients With Milder CF, Study Contends - Cystic Fibrosis News Today

MLS expansion side Inter Miami (set to begin play in 2020) announced the signing of 19-year-old attacking midfielder George Acosta. The Miami native is the fifth player and first American to join Inter Miami.

Acosta joins Miami from USL Championship side Austin Bold FC, which he signed for in August after leaving Argentine powerhouse Boca Juniors. Acosta played for Bocas U-20 and reserve teams, but was unable to break into the first team.

He will remain with the Bold until January 2020. He has made two appearances for the club and recorded one assist.

Acosta has been a long-time U.S. youth international and was called in for a U-23 training camp in June. He played with the U.S. at the 2017 FIFA U-17 World Cup in India, making two appearances and scoring one goal.

The U.S. advanced to the quarterfinals in that tournament before losing 4-1 to Brazil. While Acosta has only featured for U.S. youth teams, he is also eligible to represent Colombia.

Originally posted here:

Inter Miami CF signs U.S youth international George Acosta - Stars and Stripes FC

CHIPPEWA FALLS When the Chippewa Falls Area Chamber of Commerce announced plans in 2002 to begin an Oktoberfest event, chamber programs director Jill Herriges jumped into planning the event.

I planned the first 11 Oktoberfests and I managed the first 10, she said.

On Friday, Jill and Steve Herriges were honored as the 2019 Festmeister and Festmeisterin, becoming royalty for the annual event now in its 17th year in Chippewa Falls.

Oktoberfest is a huge part of our life, with my family and my extended Oktoberfest family, Jill Herriges said. Its a huge honor.

Jerry Jacobson, 2003 Festmeister, praised the selection of the Herrigeses.

She was instrumental in getting it started. She did all the grunt work in the beginning, Jacobson said. Without her, we wouldnt have had an Oktoberfest. Its great to see her as part of the royalty.

Jill Herriges left the chamber in 2014. She served as marketing director at Northwestern Bank and also was director of the Chippewa Area Mentor Program. In August 2018, she became executive director of the Community Foundation of Chippewa County. Steve Herriges works in human resources at JAMF in Eau Claire. He said they have been to at least one day of the event all of the past 16 years.

It is awesome for Jill and I to be here. Were humbled, he said.

Bill Febry, the first-ever Festmeister in 2003, described the couple as great community members.

She developed the event, beginning in 2002, until it actually began in 2003, Febry said. Its the appreciation of what theyve done.

Ian Kopp, 2016 Festmeister, echoed praise for the Herrigeses.

Its their leadership and vision at the beginning, Kopp said. They created such an amazing event that benefits so many people in Chippewa Falls.

Jake Leinenkugel, 2012 Festmeister, said hes known the couple for more than a decade, saying they have always been attached to the community.

I cant think of a more deserving couple, and they always have smiles on their faces, Jake Leinenkugel said.

Peg Leinenkugel, 2013 Festmeisterin, was pleased with the announcement.

Jill and Steve have done so much for the community, she said. Jill has quietly worked for so many different organizations and events, and she never expects any recognition. Shes just an exceptional person.

Jill Herriges, 49, was born and raised in Chippewa Falls. They lived in Mount Horeb, moving back to the area in 2000.

The identity of the royal couple is always a secret. Fewer than five people including the royals know the winners until the unveiling. Jill and Steve Herriges were asked in the spring, but they couldnt tell anyone.

You want to share the excitement, and intimately see the reactions on faces, so its been tough (keeping the secret), Steve Herriges said.

Jill Herriges added: (Lying) is not the norm for me. I look at it as keeping information from people, not lying.

Even their 18-year-old daughter Emma didnt find out until she saw their outfits Wednesday night.

Her reaction was, Youve got to be kidding me, Jill Herriges said.

Oktoberfest typically draws 14,000 patrons over the course of the weekend.

Since the beginning of Oktoberfest in 2003, the Planning Committee has donated more than $345,000 to local community groups and non-profits, including $20,000 last November from the 2018 event.

Todays events include a keg rolling competition at noon, the Glockenspiel comedy team has performances at 4 p.m. and 9 p.m., the beer stein holding competition is at 7 p.m., and the sauerkraut eating competition at 7:45 p.m.

Performers today include the Marshall Star Band, Rural Route 5, Maleks Fisherman and Shirts & Skins.

Sunday includes the polka ecumenical celebration at 10:30 a.m. and magician Kevin Hall at 12:30 p.m.

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Former CF Chamber official, husband honored as Oktoberfest royalty - Leader-Telegram

Wefunder, the leading crowdfunding platform using the Reg CF securities exemption, has posted a comment letter on the Securities and Exchange Commissions concept release authored by Wefunder co-founder and CEO Nick Tommarello.

The SECs concept release is an ongoing consultation on the current regulatory environment for exempt securities offerings. Wefunder has offered securities under Reg CF as a FINRA regulated funding portal but the platform has also issued securities under both Reg D and Reg A+. It is widely known that Reg CF has been an effective tool for companies to raise capital but current rules have hampered its development and success. Under Reg CF, issuers may raise capital from both accredited and non-accredited investors via FINRA regulated funding portals or broker-dealers within a strict set of limitations.

According to Tommarello;

As the rules stand right now, Regulation Crowdfunding (Reg CF) is most often a funding option of last resort. Issuers even often choose to raise no money rather than potentially hamstring their future.

Tommarello provides advice as to how to fix the shortcomings of Reg CF while providing insight into necessary changes to the definition of an accredited investor as well as comments on both Reg A+ and Reg D.

Regarding improvements to Reg CF, Tommarello suggests the following:

Regarding the definition of an accredited investor, Wefunder recommends a fix that allows for a sophistication qualification as a wealth metric is not the best method of judging investing acumen.

Pertaining to Reg D, a securities exemption currently only available to accredited investors, Wefunder believes it is important that non-accredited investors are able to access these investments but only if:

There is more.

Wefunder is not alone in advocating for fixes to Reg CF, as well as improvements to Reg D, Reg A+ and the definition of an accredited investor. The SEC Concept Release is accepting comments until September 24th. It is not clear what changes the SEC will be willing to make or if the Commission expects Congressional action.

The Wefunder letter is embedded below.

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Wefunders Nick Tommarello Posts Comment on SEC Concept Release: Currently, Reg CF is Most Often a Funding Option of Last Resort - Crowdfund Insider

NEW YORK--(BUSINESS WIRE)--Kroll Bond Rating Agency (KBRA) is pleased to announce the assignment of preliminary ratings to 18 classes of CF 2019-CF2 (see ratings list below), a $802.9 million CMBS conduit transaction collateralized by 48 commercial mortgage loans secured by 136 properties.

The collateral properties are located in 26 states, with the top three states represented by Florida (11.9%), New York (11.5%), and California (10.9%). The pool has exposure to all the major property types, with the top three being retail (19.9%), multifamily (18.6%), and office (16.5%). The loans have principal balances ranging from $3.0 million to $68.0 million for the largest loan in the pool, GNL Office and Industrial Portfolio (8.5%), which is secured by 12 single-tenant industrial and office properties located in 10 states that together comprise 2.2 million sf. The five largest loans, which also include Uline Arena (5.2%), Ocean Edge Resort & Golf Club (5.0%), Inland Life Storage Portfolio (4.9%) and Bushwick Avenue Portfolio (4.5%), represent 28.1% of the initial pool balance, while the top 10 loans represent 46.8%.

KBRAs analysis of the transaction incorporated our multi-borrower rating process that begins with our analysts' evaluation of the underlying collateral properties' financial and operating performance, which determine KBRAs estimate of sustainable net cash flow (KNCF) and KBRA value using our U.S. CMBS Property Evaluation Methodology. On an aggregate basis, KNCF was 7.1% less than the issuer cash flow. KBRA capitalization rates were applied to each assets KNCF to derive values that were, on an aggregate basis, 42.5% less than third party appraisal values. The pool has an in-trust KLTV of 99.4% and an all-in KLTV of 106.4%. The model deploys rent and occupancy stresses, probability of default regressions, and loss given default calculations to determine losses for each collateral loan that are then used to assign our credit ratings.

For complete details on the analysis, please see our pre-sale report published at http://www.kbra.com. The preliminary ratings are based on information known to KBRA at the time of this publication. Information received subsequent to this release could result in the assignment of ratings that differ from the preliminary ratings.

Preliminary Ratings Assigned: CF 2019-CF2

Class

Initial Class Balance

Expected KBRA Rating

A-1

$20,649,000

AAA (sf)

A-2

$40,987,000

AAA (sf)

A-SB

$28,718,000

AAA (sf)

A-3

$39,556,500

AAA (sf)

A-4

$100,000,000 - $214,000,000

AAA (sf)

A-5

$218,123,500 - $332,123,500

AAA (sf)

A-S

$67,243,000

AAA (sf)

B

$36,131,000

AA+ (sf)

C

$37,134,000

A (sf)

D

$24,087,000

BBB+(sf)

E

$18,066,000

BBB (sf)

F

$19,069,000

BB (sf)

G

$8,029,000

B+ (sf)

NR-RR

$31,113,052

NR

X-A

$562,034,000

AAA (sf)

X-B

$140,508,000

AAA (sf)

X-D

$42,153,000

BBB (sf)

X-F

$19,069,000

BB (sf)

X-G

$8,029,000

B+ (sf)

Loan-Specific Certificates3

SWA

$5,130,000

NR

SWB

$5,070,000

NR

SWC

$5,890,000

NR

SWD

$6,190,000

NR

SWE

$5,620,000 - $5,820,0004

NR

SWRR

$1,900,000 - $2,100,0004

NR

SWX1

$10,200,000

NR

SWX2

$12,080,000

NR

1 The exact initial certificate balances will not be determined until final pricing, however, they are expected to fall within the above ranges; the aggregate initial certificate balance of the Class A-4 and Class A-5 certificates is expected to be approximately $431.1 million.2 Notional balance.3 Loan-specific certificates are only entitled to amounts received with respect to The Stanwix Subordinate Companion Loan.4 The exact initial certificate balances will not be determined until final pricing, however, they are expected to fall within the above ranges; the aggregate initial certificate balance of the SWE and SWRR certificates is expected to be approximately $7.2 million.

To access ratings, reports and disclosures, click here.

Related Publications: (available at http://www.kbra.com)

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About KBRA and KBRA Europe

KBRA is a full-service credit rating agency registered with the U.S. Securities and Exchange Commission as an NRSRO. In addition, KBRA is designated as a designated rating organization by the Ontario Securities Commission for issuers of asset-backed securities to file a short form prospectus or shelf prospectus. KBRA is also recognized by the National Association of Insurance Commissioners as a Credit Rating Provider, and is a certified Credit Rating Agency (CRA) by the European Securities and Markets Authority (ESMA). Kroll Bond Rating Agency Europe Limited is registered with ESMA as a CRA.

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KBRA Assigns Preliminary Ratings to CF 2019-CF2 - Business Wire

The top strikers and forwards in FIFA 20 and where to findthem.

The best FIFA Strikers are the kings of the game's business end, and with this year opening up to a few more goals than previous editions, they'll play as important a role as they ever have.

Here on this page, we'll be listing FIFA 20's best strikers - which includes the best FIFA ST, the best FIFA CF, and the best LFs and RFs, too, ranked in order of their overall rating.

Be sure to take also look at the specifics depending on what you want out of them, beyond the obvious points of Finishing, and Long Shots, and think about aspects like Ball Control and Short Passing if you prefer to play with two up top, or Heading and Strength if you like a big target man who's a threat in the air.

For other stats-based guides, it's worth taking a look at our list of the highest potential FIFA 20 wonderkids, plus we have pages on FIFA 20's best Goalkeepers, FIFA 20's best Defenders, the FIFA 20's best Midfielders and FIFA 20's best Wingers in the game, too.

Without further ado then, let's dive in! Messi moving over to Right Wing leaves Cristiano Ronaldo a clear run at top spot, while Arsenal's front two looks rather formidable, especially with FIFA 20 bringing back the speed meta.

FIFA 20 best Strikers (ST)

No LFs or RFs make the combined top 10 of the "Forward" positions this year, as those positions do less and less to justify their inclusion at all. Griezmann takes top spot, and Roberto Firmino can rightfully feel a little hard done by in 6th, as one of the very best False 9s in the real world.

FIFA 20 best Centre Forwards and Forwards (CF, RF, LF)

Looking for more on FIFA 20? So far we have the key details on the FIFA 20 release date, a list of the top FIFA 20 potential wonderkids: the best young players and hidden gems, the full FIFA 20 player ratings and top 100 players, an in-progress FIFA 20 Ones to Watch OTW players list, and a full FIFA 20 Icons list, too. Finally, check out our pages on FIFA 20 five star skillers, plus the best FIFA 20 goalkeepers, best FIFA 20 defenders, best FIFA 20 midfielders, best FIFA 20 wingers, and best FIFA 20 strikers for an in-depth look at each position.

As we alluded to above, there are a few additional things to bear in mind when choosing your strikers and forwards in FIFA 20, with slightly different factors becoming more or less important depending on the mode and formation you're playing.

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FIFA 20 best strikers - the best ST, CF, LF and RFs in FIFA - Eurogamer.net

Soccer is 90 percentabout goals. If you can score goals and lots of them, then chances area win is imminent. In FIFA 20, the game is as much a player likeyou. It has equal opportunities of planting a shot down and having it the back of the net as you do with your controller. You can get yourself in a fantastic position for a shot on goal, but itdoesnt guaranteethey're going toscore.

So when it comes to FIFA 20 and scoring, you need players who can finish and competewell. Having strikers rated 60 in front of a team made up of 85+ midfielders and defense can only take you so far. Thats where this guide comes into play.

Here are a selection of the best strikers in FIFA 20 Career Mode, with age taken into consideration

Its difficult to put into words how easy Lionel Messi makes scoring goals look. Last season, he bagged 51 goals in 50 appearances. And hes still only 32! Fantastic finisher with unbelievable dribbling skills, Messi is STILL one of, if not the best strikerin the world, and thats reflected in FIFA 20.

Stats:

Finishing: 95

Composure: 94

Dribbling: 97

Ball Control: 96

Reactions: 95

Its fair to say that Eden Hazard carried Chelsea for a long time. His skill and ability on the ball is a level above almost anyone in the Premier League. Its no wonder Real Madrid splash the cash on this astounding player.

Stats:

Acceleration/Balance: 94

Finishing: 84

Dribbling: 95

Ball Control: 94

Composure: 91

A huge contributing factor to the success of Liverpool manager Jurgen Klopps reign, Salah went from an outstanding winger to a dynamite attacker altogether. Lightning quick, and he's great on the ball. Salah might work best as a winger, but you can turn him into a fantastic striker.

Stats:

Acceleration: 94

Sprint Speed: 92

Finishing: 90

Reactions: 92

Dribbling/Ball Control: 89

The amount of hype surrounding Mbapp after his successful first season at Monaco was unlike anyone ever before him. The expectation to deliver for a man who cost a reported 180 million at 18 years old was monstrous. In his first season, he got 21 goals in 44 games. Last year, 39 goals in just 43 caps. Mbapp was already a superstar, but right now, in life and FIFA 20 Career mode, hes set to become the best in the world.

Stats:

Acceleration/Sprint Speed: 96

Agility: 92

Finishing: 89

Positioning: 89

Dribbling: 91

One ofFIFA 20s best finishers, Harry Kane is a little different from other players on this list. He doesnt pace quite as they do. Instead, he relies on being one of the best footballing brains in the business. His height also makes him deadly on a cross and is one of the best penalty takers you can buy too.

Stats:

Finishing: 94

Heading Accuracy: 86

Positioning: 93

Composure/Reactions: 91

Shot Power: 90

A player who is significantly cheaper thanthe above, Timo Werner has great attributes in all the right places. Excellent finishing, pacey, with good agility and reactions, and attacking positioning all point to a striker who knows how to score goals. Still, room to improve too. If Mbapp is out of your price range, Werner is an excellent choice.

Stats:

Acceleration: 93

Sprint Speed: 92

Finishing: 86

Positioning: 85

Ball Control: 84

Read more from the original source:

FIFA 20 Best Strikers in Career Mode | Best ST, CF - Gamepur

A biosimilar of dornase alfa inhalation solution, with the same therapeutic activity asPulmozyme, its reference therapy, was approved foruse in Russia,Selexis and Generium Pharmaceutical announced.

A biosimilar is like a generic formulation of an approved biological treatment in that it is clinically similar to its reference medicine.

Named Tigerase, this is the first dornase alfa biosimilar made available anywhere in the world to treat people with cystic fibrosis (CF). We believe patients will be able to maintain a higher quality of life on our dornase alfa inhalation solution, Dmitriy Kudlay, MD, CEO of Generium, said in a press release.

CF is caused by mutations of the CFTR gene that prevent cells from managing their salt and water balance. This imbalance triggers an accumulation of thick mucus in the organs that include the lungs, resulting in inflammation, repeated bacterial infections, increased scarring (fibrosis), and the possibility of respiratory failure.

Pulmozyme, marketed by Genentech, has been a standard therapy for CF patients since it was first approved in the 1990s. It is a synthetic version of the human deoxyribonuclease I enzyme (or rhDNase I), which selectively breaks down the long strands of DNA sequences that contribute to mucus thickening. Pulmozymes use makes the mucus thinner and easier to cough up.

Used in combination with antibiotics, bronchodilators, and steroids, Pulmozyme can significantly improve airway flow and help prevent bacterial infections.

The new dornase alfa biosimilar was developed using Selexiss SUREtechnology Platform, which uses the companys proprietary, high-performance mammalian cell line (SURE CHO-M Cell Line) to generate higher yields and more stable production of recombinant proteins that can be used as therapeutic agents.

There are currently 122 clinical programs in development utilizing our platform. The increasing number of Selexis-generated research cell banks used in clinical programs, and now a sixth marketed product, continue to validate the value of our scientific innovation, said Igor Fisch, PhD, CEO of Selexis. We are extremely proud of our ability to help our partners address complicated and intractable diseases by developing complex protein therapeutics faster, safer and more cost efficiently.

Generium, a Russian biopharmaceutical company focused on diagnostic tools and therapies that include those for rare diseases, describes itself as the first worldwide to develop and market a biosimilar of dornase alfa.

The orphan drugs market has been growing significantly over the last several years. Biotechnology, as a science, is developing rapidly, providing new products for the treatment of the most severe and rare diseases, Kudlay said.

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1st CF Biosimilar of Dornase Alfa Inhalation Solution Approved in Russia - Cystic Fibrosis News Today