Category Archives: Cf

This past week in Luxembourg, Valencia CF, TM Grupo Inmobiliario, LALIGA, INNSIDE by Meli Luxembourg and the Luxembourg Chamber of Commerce continued their international tour discussing sustainable tourism. Businessmen, investors, clients and institutional representatives of the country were present at the event.

TM Grupo Inmobiliario, the Alicante-based holding company notable for responsible residential, hotel and vacation tourism and specialists in the construction and promotion of homes along the Mediterranean and Caribbean coast, shared their sustainability and corporate responsibility strategy with 50 environmental, social and good governance commitments. These are structured around the strategic axes of climate action, sustainable construction, people and shared social value.

Jorge Blay, Europe Office Manager for TM, spoke about the possibility of sharing TM's vision of sustainability in this international tour of afterwork events. Luxembourg is one of the countries where clients have shown the greatest interest in this matter, converting it into one of their main decision elements for investment.

Joseba Arriortua, vice president of the Luxembourg Chamber of Commerce, added We are receiving more and more inquiries from residents of Luxembourg and Belgium, who want to invest in the Mediterranean area and especially in the region and city of Valencia. These events allow us to demonstrate that sectors such as residential tourism or construction are pioneering and competitive in terms of sustainability.

Julio Daz, from the Spanish Embassy in Luxembourg, stated that From a professional point of view and as an embassy, any act of this type that involves bringing Spain to Luxembourg is obviously relevant. There is a lot of capital here that is looking to be invested, so it is wonderful that they are committed to promoting Spain, the Mediterranean and Valencia.

Andrea Oriol, Delegate for LALIGA Global Network Benelux, commented that I think we can be proud of how we are all involved in the international expansion of sustainable tourism, sharing our strategies, experiences and successes. Thanks to the support of a partner like TM Grupo Inmobiliario, we have the possibility of communicating in different European countries.

On behalf of the Melia Hotel, Javier Segura, Resident Director at INNSiDE by Luxembourg, said that sustainability is one of the basic pillars of Hotel Melia and INNSiDE by Luxembourg within the 2030 agenda. During the last two years we have been chosen as the most sustainable hotel company worldwide, which is a source of pride."

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Valencia CF, TM Real Estate Group and LaLiga continue their international journey about sustainable tourism - Valencia CF

Cystic Fibrosis Foundation Board Chair - the First Person with CF to Ever Lead the Organization - Discusses the Rare Disease, Outliving Your Life Expectancy, and the Path to a Cure

NEW YORK, NY / ACCESSWIRE / May 20, 2024 / Cystic fibrosis (CF) is a rare, progressive, and genetic disease that currently affects about 40,000 people in the United States. CF is the result of a defective gene, inherited from each parent, and the disease can impact people of all races and ethnicities. Recently, KC White, Board Chair of the Cystic Fibrosis Foundation, participated in a nationwide satellite media tour to discuss the disease, her personal journey, and how the Foundation is helping progress care and treatment options.

A video accompanying this announcement is available at: https://youtu.be/8wj8u0JEqLU

Cystic Fibrosis Foundation Board Chair - the First Person with CF to Ever Lead the Organization - Discusses the Rare Disease, Outliving Your Life Expectancy, and the Path to a Cure

CF is a life-shortening disease that prevents our bodies from clearing mucus. This can lead to lung infections, poor nutrition, lung disease, and a host of unique challenges that can impact every aspect of a person's life. When it was first discovered, it was considered a fatal pediatric disease. But due to transformative advancements in treatments and high-quality care, the life-expectancy for someone born with CF today is 56. While that number is climbing there is still a long way to go and unfortunately, not all people with CF equally benefit from this progress.

KC White was elected chair of the Cystic Fibrosis Foundation's Board of Trustees in 2022 after serving on the Board since 2005. Diagnosed with cystic fibrosis at age 3, White has been a committed volunteer and inspiring advocate for the Foundation since childhood and is the first person with CF to serve as board chair. When she was diagnosed, she wasn't expected to live past high school age, but her family refused to accept that fate, which prompted their dedication to the Foundation's work.

Because of recent treatments known as modulators, about 90% of the CF population (including KC) experienced an incredible transformation in their health. With this though, comes navigating unplanned challenges including careers, finances, family, and more. In addition to fueling the research, particularly in genetic therapies, that will lead to transformative treatments for the entire CF population, the CF Foundation works to support the CF community in all aspects of their lives through support programs and fostering connection opportunities.

Every May, the cystic fibrosis community comes together for CF Awareness Month to educate the public about the rare disease, share personal stories, and encourage people to get involved and unite behind a shared mission: finding a cure for all people with CF. The CF Foundation is committed to finding a cure and providing all people with CF the opportunity to lead long, fulfilling lives. The Foundation is aggressively funding research and drug development, advancing high-quality, specialized care, and partnering with and advocating for the CF community.

For more information, visit CFF.ORG/CFMONTH

About KC White KC White was elected chair of the Cystic Fibrosis Foundation's Board of Trustees in 2022 after serving on the Board since 2005. Diagnosed with cystic fibrosis at age 3, White has been a committed volunteer and inspiring advocate for the Foundation since childhood, speaking at her first Foundation event when she was only 9 years old. She is the first person with CF to serve as board chair. White received her Master of Applied Positive Psychology from the University of Pennsylvania in 2022 and currently serves as an assistant instructor in the program. She is also the Head Varsity Women's Lacrosse coach for the Chagrin Falls, Ohio, Tigers. She and her husband, Justin, have one son, Mac.

About the Cystic Fibrosis Foundation The Cystic Fibrosis Foundation is a donor-supported nonprofit organization leading the relentless pursuit of a cure for cystic fibrosis. The Foundation is committed to providing all people with CF the opportunity to lead long, fulfilling lives by funding research and drug development, advancing high-quality, specialized care, and partnering with and advocating for the CF community.

The Foundation funds more CF research than any other organization, and nearly every CF drug available today was made possible because of Foundation support. The organization supports and accredits a national network of over 130 CF care centers recognized by the National Institutes of Health as a model of care for a chronic disease. Also, the Foundation manages support programs and fosters connection opportunities for the CF community. Based in Bethesda, Md., the Foundation's impact is made possible by the work of nearly 70 local chapters across the country.

Contact Details YourUpdateTV +1 212-736-2727 [emailprotected]

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Shedding Light on Cystic Fibrosis Awareness Month - AccessWire

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MLS: Canadian Championship-Quarterfinal Round-Forge FC Hamilton at CF Montreal - Henry Herald

Inter Miami CF (8 wins, 4 draws, 2 losses) welcomes D.C. United (4-5-4) to Chase Stadium Saturday. Kickoff is set for 7:30 p.m. ET (Apple TV). Below, we previewFanDuel Sportsbookslines around the Inter Miami CF vs. D.C. United odds, and make our best expert MLS picks and predictions.

Inter had its 5-game win streak snap Wednesday in a 0-0 road draw with Orlando City. It still sits atop the Eastern Conference despite the disappointing result. F Lionel Messi, who leads the teams dynamic offense, sat out due to a knee injury but is not on the injury report for Saturday. When Messi captains the team, Inter is 7-1-0. It is 4-2-1 at home this season.

United sits 8th in the Eastern Conference with a -3 goal differential. Its defense has struggled, allowing 23 goals, but its offense has the 5th-most goals in the conference (20). It is coming off a 4-1 home loss to the New York Red Bulls Wednesday. United is just 2-1-3 in its last 6 games. F Christian Benteke is leading the team, having netted 11 goals in 11 matches.

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Provided byFanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:50 a.m. ET.

Inter Miami 3, D.C. United 1

PASS.

Inter is the far more put-together side and has the experience and technical expertise to win the game.

Inter is 4-0 at home when Messi captains the team. The odds reflect that, and at -195, theres not much value in backing the home side.

BET OVER 3.5 (-110).

Messi is the engine that keeps Inter going. Inter has scored 24 goals in the last 6 games in which Messi has played.

United has given up at least 2 goals in 3 straight games to less potent attacking sides. It has also scored 2 goals per game over its last 4. United has strong attacking players in Benteke and should be able to break through on a Miami defense that has allowed 20 goals in 14 matches.

Expect a high-scoring battle, and take OVER 3.5 (-110).

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Inter Miami CF vs. D.C. United odds, picks and predictions - USA TODAY Sportsbook Wire

For the fourth time in tournament history and the second time this week, a Canadian Premier League side has prevailed over its MLS counterpart and this one will be heading to the Canadian Championship semi-finals.

Forge struck first blood against Montreal and backed it up with another goal in the first half, with a beleaguered CF Montreal unable a conjure a coherent comeback against the reigning CPL champions a team theyd never lost to in four previous meetings.

CF Montreal kicked off with a slight advantage in hand through away goals, having gotten away with a 1-1 draw in a well-attended Tim Hortons Field Schoolday match two weeks ago.

Forges starting eleven was largely unchanged from their last outing, with only one roster swap though notably, Smyrniotis called upon Kwasi Poku to start right up top tonight, giving fans their first glimpse of the youngster as a striker.

Montreal, meanwhile, tallied five changes from their squad which had played Forge two weeks ago, and seven from their thumping league defeat against Toronto FC though one consistent was Nigerian striker Sunisi Ibrahim, who once scored a hat trick against Forge and had the sides lone goal against TFC last weekend.

While fans may have raised their eyebrows at Poku in a number nine role, he opened the shooting with a powerful out-of-the-box effort that rose just above the bar. Borges would then slide an inch-perfect through ball to David Choiniere that was only denied by a brilliant tackle from Corbo, showing that Forge had come in hungry for goals.

The warning lights now flashed, Forge pounced soon after: a quick transition from the visitors saw Badibanga send a ball in from the left flank to CF Monterrey loanee David Parra, with the Mexican duly firing above the mitts of Breza to put Forge ahead on aggregate as a quietness enveloped Stade Saputo:

CF Montreal found themselves spurred to life afterwards, generating a slew of rapid-fire chances that tested the Forge backline and young goalkeeper Christopher Kalongo, who held firm with some fine saves.

I Trust In My Ability: Kalongo Enjoying Opportunity To Impress As Forge Starter

The hammers would put themselves up by two after brilliant ball up the right flank saw Kwasi Poku get the best of his marker, with the youngster darting into the box and slotting a left-footed shot beyond Breza to leave Montreal with a mountain to climb.

Now needing three goals, the hosts found themselves subjected to jeers and whistles from fans who would need two hands to count the games since their last win.

The bell would ring for Montreal briefly on the half hour mark as a nice ball in from Ilias Illiadis resulted in an offside goal for the hosts, fooling some of the crowd to spring to their feet momentarily.

The best opportunity for the hosts came in the closing moments of the first half, but Kalongo would keep his clean sheet intact with two fine stops to avoid any changes to the dynamic during the half-time interval.

A weather delay from lightning prolonged the feelings of unease for Montreal, with over an hour and a half passing before the second half of the game could unfold.

Montreal head coach Laurent Courtois made a rare triple change to help breathe life into the hosts for the second half, with Jules-Anthony Vilsaint, Ariel Lassiter, and Fernando Alvarez coming on for Le CFM.

The changes added some definite bit for the hosts, who quickly called Kalongo into action and looked more threatening on the counter, with Bekker verging on the line of a penalty shout from Marie-Soleil Beaudoin as he bowled an attacker over in the box, though no whistle came.

The sustained pressure eventually paid off, with a multitude of corner kits eventually landing an opportunity for Victor Wanyama the chance to ping a powerful header into the back of the net:

Forge boss Bobby Smyrniotis sensed the momentum shift, taking off Poku for the more defensive-minded Malik Owolabi-Belewu after Kalongo was forced to produce another fine save with twenty minutes to go.

Corbo nearly levelled the score fifteen minutes from time, firing a header just inches wide of the post. The hammers would cling on to the result, however, recording not just a win on the night, but a historic victory over CF Montreal as they march on to the semi-final stage.

This low point for CF Montreal now sees them winless in its last eight matches and knocked out of the cup by a team with a much smaller salary cap, positing big questions to club brass. Weather delay or no, there is a big storm brewing -nay, chaotically thriving for the MLS side.

Forge will now march to a semi-final stage that includes two MLS teams with Toronto FC and the Vancouver Whitecaps securing passage earlier this week, though the Caps cut it close. Next week will see Pacific FC and Atletico Ottawa play to determine the other CPL entrant to the penultimate round.

Forge has long-been a flagbearer of the Canadian Premier League, and that was on display tonight after they danced to their own drums in the 514. Having come one match away from lifting the trophy in be belated 2020 Final, theres a firm believe the hammers could go all the way this time in 2024.

Header Image Photo Credit: Audrey Magny

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CF Montreal Falls To Forge In Canadian Championship - Northern Tribune

Itll be Memorial Day weekend inside the United States this last weekend of May. Every year at this time, MMAs top promotion, the UFC, takes time away from the famed Octagon, this year ahead of UFC 302 on June 1. Just because Dana Whites promotion has a bye this week, it doesnt necessarily mean that the cupboard is bare when it comes to competitive violence.

In actuality, the plate is still pretty full even without the UFC in action on the extended holiday weekend stateside. Its a big Saturday of fights and itll kick off in Alkmaar, The Netherlands for Brave CFs second event this month and third in the last five weeks.

Brave CF 83 marks the first card ever to be held in The Netherlands from the promotion, in association with ECE MMA from Enfusion. Saturdays card breaks a record with The Netherlands becoming the 14th host nation in Europe to hold a Brave CF card.

Inside the United States, Brave CF 83 will be seen on DAZN at 11:30 am ET/ 8:30 am PT. All told, absent of any postponed fights between now and the weekend, the final version of the show features six bouts on the docket. At the top of the bill is a nontitle fixture at super-welterweight (175 lbs.) in the Brave CF 83 main event.

Former Brave CF Super-Welterweight Champion Marcin Bandel (22-8-1 MMA, 3-1 Brave CF) returns to the cage to face off against 33-fight veteran Alex Lohore (23-10 MMA, Brave CF promotional debut,) a veteran of fellow DAZN stablemate Oktagon MMA, in the Brave CF 83 main event.

With no title at stake in the Brave CF 83 main event, this headliner is a maximum of three rounds at five minutes per round to close the show.

Heading into the Brave CF 83 main event on Saturday afternoon, debutante Alex Lohore stands as the taller man at 6-foot-1, compared to the 5-foot-11 frame of Marcin Bandel. Bandel owns a 70-inch reach, with no such information available for Alex Lohore at press time.

Currently, the oddsmakers do not have any money lines listed for Saturdays action. If you plan on betting on this or any other fight happening this weekend, please wager responsibly.

Marcin Bandel goes into the Brave CF 83 main event this weekend having gone 4-1 in his last five fights. Most recently, he saw a four-fight winning streak snapped at the hands of undefeated Kamal Magomedov (11-0 MMA, 3-0 Brave CF) at Brave CF 77 in Isa Town, Bahrain (first-round knockout: knees and punches).

Despite the defeat back in December, Bandel has the support of his home country, Poland. A former UFC lightweight who went 0-2 between October of 2014 and April of 2015, hes climbed the mountain over the course of the last nine years and won a championship.

Will Marcin Bandel get his hand raised by the referee on Saturday night? Rest assured, his fellow countrymen will be watching the Brave CF 83 main event and rooting him on.

In the other corner, Alex Lohore, who is also an alumnus of Bellator MMA and Cage Warriors, has posted a record of 2-3 in his last five MMA fights. Hes been a bit of a streaky fighter of late in the cage.

Currently, hes on a two-fight losing streak, one which was extended last time out with a first-round knockout (right hook) by Ion Surdu (14-6 MMA, 2-2 Oktagon) in Oktagon 48 last November. In order to find Lohores last sustained winning streak, youd have to travel back in time almost six years to between September and December of 2018, where he won three consecutive fights in a span of 90 days, including two Cage Warriors fights in a month and a halfs time.

This is a man who once rattled off 10 consecutive wins early on in his career as a fighter. A win in the Brave CF 83 main event on Saturday is a step in the right direction, so will he stop the skid on Saturday? Only time will tell.

Stylistically, the Brave CF 83 main event looks to favor Marcin Bandel, a Brazilian jiu-jitsu practitioner, compared to Alex Lohores background as a boxer.

Statistically speaking, Marcin Bandel has 19 career wins by way of submission, so once a fight goes to the cage mat, it could be a matter of moments before the final bell rings. While there are many prime examples of this on video, Bandels win against Ismail Naurdiev is pretty slick.

During the first round of a scheduled three, Marcin Bandel knocked Ismail Naurdiev down with a crisp punch to the head. He then quickly scrambled to take back mount, grappling with Naurdiev, applying the torque to secure an armbar submission in just under 80 seconds to add a win to his record.

All it will take Marcin Bandel to get back in the win column during the Brave CF 83 main event is to get Alex Lohore down by any means necessary.

In the other corner, just as Marcin Bandel is adept in grappling, Alex Lohore can end the Brave CF 83 main event with one single blow. Just look at the tape of his win against Matus Juracek in Oktagon from the end of 2022.

Right after the command to fight was given in the third and final round of the bout, Lohore absorbed a strike from Juracek, causing the former to move in and land a perfectly-placed left hook to drop Juracek on contact. Lohore landed some ground and pound shots to ensure that enough damage was done and the referee waved off the contest in 16 blistering seconds.

The best way for Alex Lohore to pacify Marcin Bandels ground game on Saturday is to get Bandel on the ground, plain and simple.

Two seasoned veterans of the sport will enter the cage on Saturday. Which one of these men will emerge as the victor?

Prediction: Marcin Bandel by First-Round Submission.

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Super-Welterweights Do Battle in BRAVE CF 83 Main Event - MMA Sucka

The Canyon Endurace CF SLX 8 AXS Aero features that classic Canyon look, with added comfort, and a super-clean monocoque cockpit. Its also got a convenient tool roll integrated into the top tube. Can this combination outperform the all-road competition, and does it live up to its Endurace name?

This bike was tested as part of the 2024 all-road shootout you can find an overview of the test field here: 2024 all-road shootout The four hottest all-road bikes head to head.

The Endurace has a very long tradition in Canyons portfolio. The first model was launched as far back as 2016. Even then, the focus was on long distances, for what used to be called marathon. Either way, the Canyon Endurace is and has always been a bike for long days in the saddle. Also on board since 2016: the now iconic Canyon S15 seat post. And, as hard as it is to believe, they even had models with rim brakes and mechanical shifting back then! But how does the current version fare, priced at 5,499, featuring an integrated tool roll, weighing 8.30 kg, and available exclusively with a wireless drivetrain and disc brake?

High-tech performance meets modern flair in the Canyon Endurace CF SLX 8 AXS Aero. Thats according to some. To others, it looks like a cold, functional engineering design. In any case, the new Endurace has an edgy, rocket-ship look that isnt necessarily aggressive but definitely hints at performance. The structured surface on the fork, seat stays, and seat tube isnt just eye-catching, it also offers aero gains, according to Canyon. Unfortunately, the Desert Grey colour isnt exactly a feast for the eyes. It looks quite vintage and gives the bike a 1996 Opel Astra vibe. Of course, this is a matter of taste, though we feel that it detracts from the bikes otherwise modern look. Fortunately, there are other colours to choose from. Be that as it may, pairing the bronze shimmer with tan-wall tires is a definite no-go! With aero in the name, the Canyon Endurace CF SLX 8 AXS Aero isnt complete without aero details. These include elongated tubing profiles, a cut-out for the rear wheel, and flat faces. The one-piece handlebar and stem unit also matches the bikes aero ambitions.

The spec of the Canyon Endurace CF SLX 8 AXS Aero leans more toward road cycling, especially compared to the other three all-road bikes on test. The deep profile rims, svelte look, and 30/32 mm front and rear tires are clearly at home on the asphalt. However, there is clearance for 35 mm tires, which would cater to gravel road excursions. A knock-block steering limiter prevents the handlebar from damaging the frame. Youve got a 12-speed SRAM Force AXS groupset paired with a 1033 t cassette and 46/33 t crankset ensuring rapid shifting, as well as a power metre. The gearing suits the build and offers sufficient range, provided you dont leave the road. The DT Swiss ERC 1400 DICUT wheelset is an excellent choice, featuring 35 mm deep profile rims with a relatively wide 22 mm internal width, which is in line with the current trend of increasing tire widths. Canyon also include a chainstay protector, which makes perfect sense, despite the road-oriented build. The Canyon S15 VCLS 2.0 CF seat post also matches the bikes looks while offering added comfort.

5,499

Fork Canyon FK0129 CF Disc Seatpost Canyon S15 VCLS 2.0 CF 27.2 mm Brakes SRAM Force AXS HRD 160 mm Drivetrain SRAM Force AXS 12s 2 x 12 Chainring 46/33T Stem Canyon CP0018 Aerocockpit 100 mm Handlebar Canyon CP0018 Aerocockpit 410 mm Wheelset DT Swiss ERC 1400 Dicut 12 x 100/12 x 142 mm Through Axle Tires Schwalbe Pro One TLE 700 x 32c 30 32 Cranks SRAM Force AXS Powermeter 46/33 172.5 mm Cassette SRAM XG 1270 10-33T

Size 3XS 2XS XS S M L XL 2XL

very compact geometry road setup through and through tool kit in the top tube supremely comfortable

Once youve swung your leg over the saddle and are rolling along, the Canyon Endurace CF SLX 8 AXS Aero will soon have you in a compact and comfortable riding position. Its rather aggressive, nevertheless. As such, the name EnduRace suits the bike perfectly in this respect. In contrast to the comfort-oriented Specialized Roubaix, it feels significantly more like it wants to race, which is further underlined by the handling. The bike is stiff and responsive, resulting in a very direct power transfer. It feels super lively upon acceleration as well as on the climbs, raring to go at every opportunity. Add to that the agile and direct steering, letting you control the Canyon Endurace CF SLX 8 AXS Aero with pin-point precision. This combination lets you summit mountains and hills in no time, and ride down even quicker. The hardest part is reigning in your enthusiasm and not pedalling all out all the time. Its a completely different riding experience, especially compared to the more comfortable FOCUS PARALANE 8.9.

The seat post and cockpit on the Canyon Endurace CF SLX 8 AXS Aero compensate for what the stiff frame lacks in terms of compliance. In fact, the Canyon S15 VCLS 2.0 CF seat post made the Endurace by far the most comfortable bike on test, at least at the rear. It takes the sting out of all road conditions, no matter how rough or poorly maintained. The Continental GP5000 tires offer plenty of grip and excellent rolling characteristics on asphalt, though youll want to avoid gravel and dirt roads with this setup. A second wheelset with grippier 35 mm tires, like the Schwalbe G One RS, could make the Endurace significantly more versatile. Lets address the tool roll in the top tube. On the one hand, its extremely convenient and easy to reach, but on the other hand, it is always in your field of view. The tool set includes all the essentials, made up of eight bits, one ratchet, tire levers, a CO cartridge, and Dynaplug, available for an additional 14.95. The set comes to 192 g. Unfortunately, it can be a bit fiddly to use, and the flap got jammed several times during our test. The plastic closure is more reminiscent of a battery compartment on a childrens toy than a premium bike. Overall, its a good idea, but the execution leaves room for improvement.

We cant think of a better name for this bike than Endurace!

The Canyon Endurace CF SLX 8 AXS Aero is a fast endurance bike for winding and fast descents. Its ideal for those who like to ride long AND fast, and predominantly on asphalt. However, with a second set of 35 mm gravel tires, you could turn the Endurace into a gravel racer. It doesnt invite you to cruise along and take in the sights, but rather to churn out watts and eat up kilometres. Group rides, all-day epics, and long-distance events are where its most comfortable.

Tuning tip: Black tires and an Opel Astra in the matching colour

Canyon Endurace CS SLX 8 AXS Aero

Size: 3XS 2XS XS S M L XL 2XL Weight: 8,3 Price: 5,499

The Canyon Endurace CF SLX 8 AXS Aero certainly lives up to its name. It combines race-oriented elements with long distance comfort. Its a bike that makes you want to ride long distances at a fast pace. However, this build is aimed more at asphalt. Before venturing off onto dirt roads, you will need to swap out the tires on the Endurace and max out the 35 mm tire clearance. With the Canyon Endurace CF SLX 8, all-road actually means road, and EnduRace.

For more information visit canyon.com

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Words: Martin Staffa Photos: Jan Richter

Original post:

Canyon Endurace CF SLX 8 AXS Aero All in the name of speed and distance? - GRAN FONDO Cycling Magazine

To capture the hearts and minds of consumers through a shared love for ftbol, Lowes is delivering a hat trick for ftbol fans. Lowes is partnering with the best ftbol player in the world, Lionel Messi, Major League Soccer Club Inter Miami CF and the upcoming CONMEBOL Copa Amrica 2024 USA.

Through a multiyear agreement, Messi also becomes a member of Lowes Home Team, making him the first ftbol player to join the lineup of top NFL and NBA athletes who have helped improve communities around the country since 2020.

Lionel Messi is the GOAT of the assist, said Jen Wilson, Lowe's senior vice president of enterprise brand and marketing. Partnering with him is the perfect reflection of Lowes shared passion for assisting our customers, whether for their business or home.

To kick off his first season, Lowes and Messi will assist Lowes loyalty customers with extra perks. Starting today, all loyalty members will receive 100 points to get them closer to their next reward through Lowes new loyalty program for homeowners, MyLowes Rewards, and Lowes MVPs Pro Rewards for Pros. MyLowes Rewards members must claim points on their account dashboard by May 18.*

Ftbol, much like home improvement, is all about teamwork and the assistance between people, Messi said. I am happy to partner with Lowes, a brand that understands the importance of collaboration and helping people succeed.

Inter Miami has quickly become the focal point of ftbol in North America. The new partnership between Lowes and Inter Miami will drive engagement with ftbol fans with signage and in-stadium activations, community programming, ticket hospitality, player appearances at Lowes locations throughout the Miami market and more.

Inter Miami has worked towards becoming a global reference point of ftbol, so that when people think of ftbol, they think of Inter Miami, said Inter Miami CF Chief Business Officer, Xavier Asensi. Our partnership with Lowes is another proof point of attaining this ambition. We are excited to partner with Lowes, an organization that matches our goal to continue to set the benchmark for the sport and deliver for our ftbol family.

Lowes will also team up with CONMEBOL Copa Amrica 2024 USA, which returns to the United States with Argentina defending its crown beginning June 20. Lowes has a series of exciting initiatives to celebrate the magic of Messi:

To celebrate ftbols rich culture and community, we wanted to partner with an athlete and ftbol affiliations that resonate deeply with our customers, said Gerardo Soto, Lowe's vice president of brand marketing and sports partnerships. These new partnerships provide an opportunity to build trust and credibility with a broader customer base through the athletes and sporting events that matter to them.

The partnerships add to Lowes existing collaboration with Charlotte FC, Lowes hometown Major League Soccer club. As the Official Home Improvement Partner of Inter Miami CF and CONMEBOL Copa Amrica 2024 USA, Lowes will enhance the ftbol experience for fans while bringing them closer to the excitement of Messi's gameplay.

For more information about Lowes partnerships and upcoming ftbol initiatives, visit Lowes.com/hometeam.

* Loyalty Programs subject to Terms & Conditions. Visit Lowes.com/Terms for details. Subject to change.

**All Bonus Points will expire on December 31, 2024, unless extended by Lowes. Reward Center items may vary. Visit Lowes.com/terms for full details.

See the original post:

Lowe's Teams Up with Lionel Messi, Inter Miami CF and CONMEBOL Copa Amrica 2024 USA to Win Over Ftbol ... - Inter Miami CF

A novel treatment strategy for cystic fibrosis (CF) thats based on a cellular structure called the porosome showed promise in cell and animal models of CF caused by the common F508del mutation.

In the cell model, this approach was more potent than tezacaftor and ivacaftor, which are CFTR modulators used in approved CF therapies,according to data presented by Porosome Therapeutics, the company developing the approach.

Findings were showcased at the April summit of the American Physiological Society in Long Beach, California, in the poster Cystic fibrosis rescued using a reprogrammed porosome secretory machinery.

These new results mark a major breakthrough in our efforts to find a path to a cure, not only for CF but for a wide range of debilitating diseases and chronic conditions, Guillermo Marmol, president and CEO of Porosome Therapeutics, said in a press release sent to Cystic Fibrosis News Today. Marmol noted that the company is focused on bringing this approach into clinical testing in people.

We are diligently conducting further studies to comprehensively assess the safety, stability, and optimal dosage of this approach, said Bhanu P. Jena, PhD, the companys founder and chairman.

CF is caused by mutations in the gene that encodes the CFTR protein. This protein normally helps regulate the flow of chloride ions across the cell membrane. Problems in the workings of CFTR lead to the production of abnormally thick, sticky mucus, which builds in organs to drive most disease symptoms.

The porosome is a complex of dozens of proteins, including CFTR, that work together to regulate the movement of molecules out of cells. The therapeutic approach described here basically involves taking porosomes from cells with healthy CFTR protein and transplanting them into CF cells.

Reconstitution of functional porosomes having normal CFTR, therefore holds great promise in treating CF with all different types of CFTR mutations, the researchers wrote.

Researchers first tested this approach in a cell model of CF caused by the most common CF-causing mutation, F508del. As in CF patients, cells in this particular model characteristically secrete lower-than-normal levels of certain mucus proteins, including MUC5B and MUC5AC.

The porosome-based treatment increased secretion of these mucus proteins from CF cells. Notably, the porosome therapy had a significantly more potent effect on mucus protein secretion compared to tezacaftor and ivacaftor, which in CFTR modulators work by boosting the functionality of the faulty CFTR protein.

These findings indicate that porosome-reconstitution therapy is a powerful approach, the researchers wrote.

Scientists next tested the porosome-based treatment in a mouse model of CF caused by the F508del mutation.

In these experiments, they evaluated the effect of the treatment on CFTR function using a well-established measure called the nasal potential difference, which records the small electrical charge that occurs in the airway lining inside the nose. Results indicated that the porosome therapy normalized CFTR function.

Porosomes obtained from functional [healthy] human bronchial epithelial cells were used to treat the nasal passages of CF-affected mice. Remarkably, within 24 hours of treatment, this reconstitution of the porosome rescued chloride secretion in the nasal passage, Jena said.

See the rest here:

Porosome treatment targeting CFTR shows promise in CF models - Cystic Fibrosis News Today

Im Yoon-ah, popularly known as YoonA, is a renowned South Korean actress and a member of the globally acclaimed girl group Girls Generation, or SNSD. In the South Korean entertainment industry, YoonA emerges as a star and an icon.

While YoonA's talents shone on stage and screen, it was her prowess in commercial endorsements that truly set her apart. Even before her official Girls' Generationdebut, she appeared in CFs. From the outset of her career, she demonstrated a natural ability to embody diverse brand images, seamlessly transitioning from cute and bubbly to sophisticated and glamorous as the occasion demanded. Her undeniable influence in the world of commercial endorsements earned her the well-deserved title of "CF Queen."

YoonA has done numerous endorsements as a member of Girls Generation, and her individual CF count is nearly 40. Some of the notable brands she endorsed are SK Telecom, Cartier Jewelry, Michael Kors, Qeelin, S-Oil, Everlands Caribbean Bay, Lee Jeans, Pandora, Ragnarok Mobile, Este Lauder, etc.

YoonA's influence transcends the border of South Korea, and she was appointed as a global ambassador for reputable brands like Miu Miu, Korea Tourism Organization, CROCS, EIDER, INNISFREE, etc.

Despite the ever-changing landscape of the entertainment industry, YoonA has remained a consistent presence in the advertising world, maintaining her relevance and desirability year after year.

Continued here:

The Reign of Girls Generation's YoonA in Endorsements: The CF Queen - allkpop