Category Archives: Cf

2021, 2012, 1992.

Montrealers saw signs emblazoned with those three years around town and online in the leadup to their MLS clubs rebranding announcement on Thursday, a hint of another new era for professional soccer in the City of Saints.

First came the birth of the Montreal Impact, at the time a lower-division side who began life in the old APSL. Nine years ago lImpact moved up to the top flight as an MLS expansion club. And now theyve been reborn as Club de Foot Montral, with a new crest, a new motto (droit devant, meaning straight ahead or always forward) and a goal of becoming a truly international outfit to better match the reputation of their cultured metropolis.

I love the Impact. This is a club and a passion project that I started along with only three full-time employees 28 years ago. And it's hard to let go of things you love, owner Joey Saputo said in Montreals live-streamed unveiling. But here's the reality. To make an impact, we need to retire the Impact. The Montreal Impact will always be that local club that made global strides, and all that, we can be proud of. In fact, that is what this vision is all about. Building a collective.

Saputo, club president and CEO Kevin Gilmore, creative co-director Justin Kingsley and head coach Thierry Henry delved into great detail to explain the roots of the rebrand one that has been greeted with some trepidation among some of the clubs hardcore supporters, but reflects the organizations conclusion that their leagues rapid evolution in turn merits fresh thinking and bold action on their part.

I asked Joey what the Impact name meant, said Gilmore. He wanted to have an impact on our sport, in the city, in this province, to which I responded, mission accomplished. That was his objective.

I asked him, Gilmore added, if he was willing to entertain, a change in branding, or name. And he said, 'I'm open to it. If you come back to me with something that is compelling. I want you to do research. I don't want to change things for the sake of changing things. There has to be a strong enough reason to do this in terms of something that speaks to who we are and who we want to be.'

So the clubs most recent marketing campaign, LImpact Montrealais, served a dual function as a research project to learn more about how fans and citizens perceived the club and their place in the citys fabric.

Soon Kingsley, a Canadian writer, filmmaker and marketer who helped coin the brand identity of the North American 2026 World Cup bid, hopped on board with his creative partner Paul Labont. They helped hatch the new crest and name and tweaked colors, which take inspiration from Montreals history, climate, architecture, arts, economy, music and even its public transportation.

In the 80s UNESCO designated Montreal as a global city of design, and it wasn't just in graphic design, it was in all facets of design, Kingsley explained on Thursday. But the reason they did this is because of the great global design era that was born here in the 60s with Expo 67, Man and His World, and then the 76 Olympic Games and all the famous, iconic design that came from those periods. So we decided to tell our modern, contemporary story to anchor ourselves in some of the visual icons that are known all over the world.

We are like snowflakes in a storm, he said. And I've seen criticisms. In fact, if you Google that word, you'll see in slang that being called a snowflake for some people is an insult. Fine. Go ahead. Insult us. Underestimate us, underestimate our team and our coach. I invite you to. To see a snowflake as a weak thing? Fine. What I'll tell you about a snowflake is that when we come together we are all individuals, we are all different and every single one of us is unique but when we come together, we form that impenetrable wall. Good luck to you defeating our storm, our blizzard.

Why Club de Foot? The desire for a traditional moniker with a specifically local, and Francophone, twist.

It was always going to be a French name, said Gilmore, but leaving that debate aside, people were saying, well, you're just going to be like everybody else FC, FC, FC. And there are X number of MLS clubs that have the FC moniker attached to it. And that's exactly it. We didn't want to be the same.

So instead of choosing between football and soccer, it's common practice in Montreal for people in French to refer to the sport as foot And Anglophones sometimes often refer to it as footy. So let's assume that, let's assume that as part of our name. Lets assume that we are different.

Saputo and Gilmore sought to place this updated identity in the wider context of Henry a world-renowned icon of the sport and sporting director Olivier Renard taking up leadership of soccer operations, as well as new hires on the communications side and what Saputo called a new partnership structure with Bologna, the Italian club he also owns.

When I first joined, Joey said, I want to take this club to another level. And to do that you have to evolve, said Gilmore. And what does that mean? We are a forward-thinking, constantly-evolving, and innovative organization. And everybody that works in this organization has to think that way.

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CF Montral explain rebrand: "To make an impact, we need to retire the Impact" - MLSsoccer.com

BETHESDA, Md.--(BUSINESS WIRE)--Today, the Cystic Fibrosis Foundation announced a new award of up to $2 million to Eloxx Pharmaceuticals Inc. to support the global Phase 2 clinical program of ELX-02, a potential therapy to treat people with cystic fibrosis who have nonsense mutations. In 2019, the Foundation provided Eloxx with an award of up to $1.6 million to support the development of ELX-02 in the U.S. This additional funding will provide continued support for a Phase 2 proof-of-concept clinical study currently being conducted in the U.S, and a related international Phase 2 study being conducted in Europe and Israel in people with CF who have at least one G542X mutation.

Preliminary results from these trials are expected in the first half of this year, which is contingent on no further disruptions due to COVID-19.

The Cystic Fibrosis Foundation is committed to accelerating treatments for the underlying cause of disease for all people with CF, said JP Clancy, MD, vice president of clinical research at the Cystic Fibrosis Foundation. We are excited to support the clinical development of a therapy with the potential to benefit individuals who currently have no approved treatment options.

Nonsense mutations (also known as x or stop mutations) cause cells to stop the production of the CFTR protein midway through the process, resulting in shortened, non-functional protein that the cell recognizes as defective and destroys. The investigational drug ELX-02 could potentially read through or bypass these premature stop signals in people with CF, resulting in the production of full-length functioning protein.

According to the Cystic Fibrosis Foundation Patient Registry, nearly 13% of people with CF in the U.S. have at least one nonsense mutation. Of that number, about 3% cannot benefit from any currently available therapy. In addition to ELX-02, the Foundation is supporting three other programs specifically focused on nonsense mutations, as well as four clinical development programs that could help people regardless of their CFTR mutations.

About the Path to a Cure

The CF Foundation launched its $500 million Path to a Cure initiative in October 2019. This initiative centers around three core strategies to address the underlying cause of CF: repairing broken CFTR protein, restoring CFTR protein when none exists, and fixing or replacing the underlying genetic mutation to address the root cause of CF. Each approach requires a different set of scientific tools and knowledge, leading the Foundation to bring together researchers and industry leaders from a range of disciplines to advance multiple areas of research in parallel. Innovators who are interested in pursuing programs in cystic fibrosis can learn more on our Path to a Cure page, which includes links to our specific funding opportunities.

About the Cystic Fibrosis Foundation

The Cystic Fibrosis Foundation is the world's leader in the search for a cure for cystic fibrosis. The Foundation funds more CF research than any other organization, and nearly every CF drug available today was made possible because of Foundation support. Based in Bethesda, Md., the Foundation also supports and accredits a national care center network that has been recognized by the National Institutes of Health as a model of care for a chronic disease. The CF Foundation is a donor-supported nonprofit organization. For more information, visit cff.org.

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CF Foundation Awards Up to $2M to Eloxx Pharmaceuticals for Additional Support of Phase 2 Clinical Studies of Potential Therapy for Nonsense Mutations...

After more than a year away from the cage, former UFC flyweight title challenger Ali Bagautinov is all set to make his return to the sport at Brave CF 46.

The event, which takes place at the WOW Arena in Sochi, Russia, represents the Bahraini promotions first foray into Russia, and the organization has stacked the card with Russian talent for the event, with Bagautinovs return set to feature in the co-main event slot.

Bagautinov (18-7) fell short in his bid to capture the Fight Nights Global flyweight strap in his last MMA outing in October 2019, and, during a year away from the cage, he ventured into boxing and defeated Belarusian Fighting Championship (BFC) flyweight MMA champion Andrey Kalechits via unanimous decision last November.

Now Puncher King is all set for his return to MMA action, and will take on fellow countryman Oleg Lichkovakha in a 130-pound catchweight matchup, with the former UFC veteran keen to return with a win on his Brave CF debut.

I dont think much of my opponent Oleg, a confident Bagautinov admitted ahead of their matchup. Let him think of me. And I calmly wait and prepare for Jan. 16. I missed the cage very much, I am hungry and angry. I want to show my best fighting qualities.

Lichkovakha, meanwhile, said hes happy to play the role of underdog against his more illustrious opponent, and the 24-year-old said hes sure Bagautinov is underestimating him ahead of their matchup.

I see him on Instagram sledding downhill in the snow and having fun. He thinks he can easily win against me, thats why he is relaxed, he said. He thinks Im a nobody, but Im fired up, I want to win. I will beat him and shock the MMA community.

Ali may have better stamina, but I have lasted three rounds in many fights and my endurance is much much better than him. His last fight was in boxing, he probably doesnt even train wrestling anymore. Im a better wrestler and grappler, I can submit him.

I will use wrestling, striking, grappling, jiu-jitsu, everything to show I am the better fighter since everyone considers me an underdog. Ali, do not relax. Ride less on the slides and be careful. Dont pull out cause you dont want to face me.

The event is headlined by a lightweight title bout as Russias reigning Brave CF super lightweight champion Eldar Eldarov puts his 165-pound title on the line against Brazilian former UFC welterweight Leonardo Mafra.

Also set for action on the card are Russian talents Roman Bogatov, Konstantin Erokhin and Rustam Chsiev.

Confirmed bouts for Brave CF 46 include:

MAIN CARD (Fite TV, 10 a.m. ET)

Here is the original post:

Brave CF 46: Returning Ali Bagautinov 'hungry and angry' ahead of Brave CF debut - MMA Junkie

Weve made it to another Friday folks. Another week is in the books in this offseason mode as we pertinently wait on when the preseason will kick off for FC Dallas and the rest of MLS.

// FC Dallas //

FC Dallas trades for Homegrown winger Kalil ElMedkhar - Big D SoccerFC Dallas makes a play for a young winger by trading for a HGP that is out of their system.

Report: FC Dallas signs Venezuelan winger on loan - Big D SoccerIt looks like FC Dallas is about to add a player that fits the mold of the type of signing we're very accustom to here.

Top Five Moments in FC Dallas SuperDraft History | FC DallasI had to read the headline on this one a couple of times, at first I thought it was top draft picks but then I saw Atuahene at number five. Moments, it talks about moments in the draft. Big difference.

Report: FC Dallas Homegrown Bryan Reynolds looks set to join Juventus | MLSsoccer.comIt seems as though every day this week a new tweet comes out stating how much closer we're at to getting this deal done.

// MLS //

CF Montral explain rebrand: "To make an impact, we need to retire the Impact" | MLSsoccer.comMontreal's new branding is a bit...eh. From dropping the name Impact (which wasn't terrible) to adding a snowflake looking butt logo (hello Greendale Community College), this one seems like a weird step in a direction that wasn't needed.

Toronto FC's next era comes to focus with Chris Armas hiring, next signings | Tom Bogert | MLSsoccer.comIt certainly wasn't the pick most Toronto fans were looking for as the club looks to move on from Greg Vanney.

For better or for worse, Armas hire means this is Ali Curtis team now - Waking The RedAli Curtis has the right motives behind what he is doing in Toronto, I will say that. But will they pan out the way he envisions them to?

Chris Henderson could be leaving Sounders for Inter Miami - Sounder At HeartOf all the moves in MLS this winter, I honestly think this could be one of the biggest.

Excerpt from:

Friday Links: Thoughts on the new CF Montreal branding - Big D Soccer

Inter Miami CF/Instagram David Beckham

David Beckham can still bend it like ... well, himself!

The retired professional soccer star, 45, joined Inter Miami CF, of which he serves as president and co-owner, for a training session on Thursday with the team's youth Academy.

After first posting a pair of snapshots last weekend that showed him visiting Inter Miami CF Stadium for the first time since the beginning of the 2020 season amid the COVID-19 pandemic (which he captioned in part, "Grateful to be back in Miami"), Beckham shared a video on Thursday of himself and the Academy members running various drills at the facility.

Other videos shared to the Inter Miami CF official Instagram feed showed the "suited up" Beckham running along the pitch, interacting with the young players and showing off the right techniques for "passing precision."

"Loved joining in with the academy players, reminded me of my early Manchester United days," the former pro midfielder wrote alongside his post. "The development of young players in our football club is so important for our future @intermiamiCF."

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Inter Miami CF/Instagram David Beckham trains with the Inter Miami CF Academy

Inter Miami CF/Instagram David Beckham

RELATED: David Beckham Buys a Luxury Penthouse in Miami, Reportedly Paying at Least $20 Million

Beckham announced the launch of his Miami Major League Soccer team during a press conference at the Florida city's Knight Concert Hall in January 2018, surrounded by fans, his financial backers and local officials.

"Bringing an MLS club to Miami has been a hell of a journey," he said at the event. "The team that we bring into this league will be one of the best teams will be the best team. When I was awarded the team, there was only one city for me. Only one city, and it was here."

Story continues

Beckham signed with the Los Angeles Galaxy in 2007 and made a deal that allowed him to buy a franchise of his own at a reduced rate, according to NPR. He first announced plans to bring a soccer franchise to Miami four years previous.

"It was very difficult at times," he said of his journey to Miami. "There was times we sat back and said, 'This is not gonna happen. This dream is not gonna happen. It's too difficult, it's too hard. There's too many bumps in the road.' But I don't give up."

RELATED VIDEO: David Beckham Teaches 6-Year-Old Daughter Harper How to Bend It Like Daddy in "First Football Lesson"

David Beckham is doing his best to make sure his sporting legacy continues and it is adorable

In April, the former captain of England's national team closed on a full-floor penthouse residence at One Thousand Museum Residences in downtown Miami, after house hunting for at least a year and a half.

"With the launch of Inter Miami CF, David and his team are spending significant amounts of time in Miami," a rep for Beckham stated in a release obtained by PEOPLE confirming the sale. "One Thousand Museum is a very special building, and we are excited to join the community here."

The real-estate acquisition was completed under Beckham Brand Limited, the partnership and licensing company owned by the superstar athlete.

Inter Miami CF began playing in MLS last year at Inter Miami CF Stadium, the site of the former Lockhart Stadium in Fort Lauderdale, Florida. They ended their inaugural season by placing 19th out of 26 teams.

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Back on the Pitch! David Beckham Joins Inter Miami CF Academy for Youth Academy Training Session - Yahoo Entertainment

RIVER FALLS, Wis.-- In the first of two games in four nights against Chippewa Falls/Menomonie, the St. Croix Valley Fusion skated to a 5-3 victory over the Sabers Tuesday night, Jan. 12, in Baldwin. The two teams will meet again Friday night, Jan. 15 in Chippewa Falls.

Jaden Woiwode scored two goals, including the go-ahead goal 19 seconds into the third period, while Olivia Dumond finished with 32 saves.

Woiwode scored her second goal 5:49 into the third to extend the Fusion lead to 4-2 and Jadyn Erickdson scored just over a minute later before CF/M scored a late goal to make the final 5-3.

Tyan Mittl scored the only goal of the first period to five the Fusion a 1-0 lead while Juneau Paulsons second period goal was sandwiched between a pair of Saber scores to make it a 2-2 game after two.

Trinity Mittl assisted on three of St. Croix Valleys five goals while Paulson, Kendall Sundby and Makenzie Weiss earned one assist each.

The win evened the Fusions record at 5-5 heading into a game against the second ranked Eau Claire Area Stars Thursday, Jan. 14 before facing the Sabers again Friday night in Chippewa Falls.

The fifth-ranked Hudson girls hockey team dominated the third period against No. 2 Eau Claire Area Tuesday night at home but it wasnt enough in a 4-3 loss to the Stars.

The Raiders trailed 3-1 going into the third and outshot the Stars 16-3 in the final 17 minutes, scoring twice, but Eau Claire was able to get a goal of its own with just under six minutes remaining to escape with the 4-3 win.

Eau Claire led 1-0 after one before Bayley Glasspoole knotted it up with a power play goal midway through the second period, assisted by Avery Johnson and Nikki Olund. But Eau Claire scored twice in the final four minutes of the period to open up a 3-1 lead.

Leah Parker made it a one-goal game at the 8:49 mark of the third, assisted by Maddy Mielke and Olund, but Eau Claire scored again at the 11:58 mark before Olund scored unassisted with under a minute remaining to make the final 4-3.

Hudson goalie Amelia Halunen finished with 16 saves as the Raiders outshot the Stars 26-20.

The Raiders, now 6-2-0 overall, will visit Chippewa Falls/Menomonie Thursday, Jan. 14, before hosting Superior in their annual Cancer Awareness Game at noon at Gornick Arena.

Originally posted here:

Fusion take round one against CF/Menomonie - RiverTowns

Every week, Combat Press takes a look at three regional, developmental and international cards from the upcoming weekend, previewing from each a single fight to which people should pay close attention. We will also list other significant bouts from the card, as well as information on how to follow each promotion and watch the events.

Lets discover those prospects that fight in obscurity, waiting for their shot at the bright lights and big stage of the UFC, and those veterans looking for one more chance at stardom.

It all begins here, from the small convention centers and high school gymnasiums to the developmental leagues that serve as a launching pad to the big show. It all begins with promotions such as these

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UAE Warriors 15/Eagle Fighting Championship 32

Spotlight Fight:Rinat Fakhretdinov (19-2) vs. Eric Spicely (12-5)

The second of this weeks collaborative efforts comes courtesy of UAE Warriors and Eagle Fighting Championship. UFC legend Khabib Nurmagomedov is heavily involved with the latter of these promotions, and this upcoming show will be a tribute to his late father. The lineup is, without a doubt, the deepest of the weekends regional and international offerings. There are a lot of bouts that demand attention, but Rinat Fakhretdinovs impressive 19-2 mark will be put to a true test against grizzled veteran and ex-UFCer Eric Spicely.

Fakhretdinov, 29, has been competing as a pro since 2013, when he suffered a debut loss. He won his next six outings before suffering another setback, this time against Igor Svirid. The Gladiator has been perfect ever since, accumulating 13 more victories while encountering varying levels of competition. While hes primarily seen very green fighters, Fakhretdinov has also managed to get the better of experienced pros like M-1 veteran Denis Gunich, UFC castoff Alberto Uda, and Brazils Jhonny Carlos. The Russian is a finisher who has registered 10 knockouts and seven submission victories in his career.

Spicely is perhaps the most familiar face here to American fight fans. He was a CES regular until his tenure on The Ultimate Fighter 23. He won two of his three bouts on the reality series, where his only defeat came in a 47-second knockout delivered by Andrew Sanchez. Zebrinha was still granted a spot on the UFC roster, but he struggled throughout his six-fight stint with the company. He was able to beat future light-heavyweight title challenger Thiago Santos in a middleweight affair and also topped Alessio Di Chirico, but those triumphs were sandwiched between a loss to Sam Alvey and a trio of setbacks handed to him by Antonio Carlos Junior, Gerald Meerschaert and Darren Stewart. Spicely, who has spent time with the Tristar camp and Syndicate MMA, returned to CES for two victories and then was brought back on short notice by the UFC, but his tough luck continued with a decision loss to Deron Winn in 2019. Spicely had a rough 2020 in which a failed weight cut led to another parting of ways with the UFC on the tail end of four scrapped fight bookings. The 34-year-old has seven submissions and four knockouts on his resume.

Spicely is an ideal gatekeeper for Fakhretdinov. The Massachusetts native is not a world-beater by any means, but hes a strong grappler who has managed to come out on top occasionally against UFC talent. However, all but one of his official UFC losses ended in a stoppage. He was submitted by Alvey and Junior, and he was finished via strikes by Meerschaert and Stewart. Fakretdinovs own high finishing rate will be put to the test against someone who can be finished in numerous ways.

Its easy to dismiss Spicely based on his losses, but they all came inside the Octagon. Furthermore, he was extremely competitive in the outings against Meerschaert and Junior. Outside of the UFC, he remains perfect while scoring numerous first-round stoppages and only going the distance twice. If Fakhretdinov does beat him, it would be a solid indicator that the Russian is ready for the big show.

Spicely is extremely awkward on the feet. His striking has improved slightly since he first joined the UFC, but his primary goal is still to get his opponent to the mat and implement his ground game. Spicely is comfortable fighting off his back and transitions well. The key to defeating him is to keep the fight standing and pick him apart, as Alvey, Stewart and Winn all managed to do.

Fakhretdinov has strong wrestling and outstanding top control, but he prefers to smother opponents rather than chaining together submission attempts. His stand-up arsenal is superior to that of Spicely. However, he does throw looping punches and lacks the polished technique that typically gives Spicely the most issues.

The outcome of this contest will depend heavily on Fakhretdinovs ability to overwhelm Spicely on the feet and not get tangled up in a grappling affair. If the fight does go to the canvas, well finally have an opportunity to see Fakhretdinovs submission defense. Spicely is certain to try to tie up his foe and could even pull guard to bring the action into his realm. Given Fakhretdinovs resume thus far and lack of action against this caliber of competition, its likely that he becomes the latest non-UFCer to fall victim to Spicely and tap out.

Other key bouts: Bruno Azeredo (14-9) vs. Mickael Lebout (20-10-3) for the lightweight title, Shamil Zavurov (38-6-1) vs. Renato Gomes (26-12), Elias Boudegzdame (16-6) vs. Jesse Arnett (17-6), Saygid Izagakhmaev (17-1) vs. Carlston Harris (14-4), Muin Gafarov (15-3) vs. Walter Zamora (11-3), Sultan Zholdoshbekov (14-1) vs. Vinicius de Oliveira (14-2), Abdurakhman Gitinovasov (5-1) vs. William Starks (4-1), Martun Mezhlumyan (10-2) vs. Daniel Vega (12-3-1), Avliyohon Hamidov (9-3-1) vs. Louis Jourdain (5-2), Shamil Magomedov (10-2-1) vs. Jayson Margallo (6-7), Mohamad Osseili (1-0) vs. Elijas Paknys (2-1), Shakhban Alkhasov (3-0) vs. Vasile Suprovici (3-3), Imamshafi Aliev (4-0) vs. Pim Kusters (2-1)

Legacy Fighting Alliance 97

Spotlight Fight:Nick Browne (10-1) vs. Arthur Estrzulas (12-4)

[Ed. Note This fight preview originally appeared on Combat Press prior to the scheduled fight between Browne and Estrzulas at LFA 95 in November. After its publication, the fight was rescheduled for LFA 97. The preview has been lightly edited here to account for the change in events.]

The Legacy Fighting Alliance lightweight title is once again vacant. Thats what happens when a promotion serves as a reliable developmental organization for the UFC. The next set of 155-pounders to essentially audition for the big show via an LFA championship affair are Nick Browne and Arthur Estrzulas, who meet in the headliner of the organizations 97th show.

Browne made his pro debut in 2014. Nyquil finished his first three foes, including future Bellator fighter Sidney Outlaw, and eventually ran his record up to a perfect 7-0 before suffering his first taste of defeat. His setback came to fellow undefeated prospect John Gunther, who used the victory as a springboard to The Ultimate Fighter 27 and, eventually, the UFC proper. Browne, meanwhile, has rebounded with three additional victories. His last two wins have come under the LFA banner against a pair of 15-fight veterans with identical 12-3 marks entering their respective contests with Browne. The 30-year-old has a solid finishing rate while nabbing five submissions and two knockouts.

Estrzulas, who debuted in 2010, enters this affair with a slight edge in experience over his fellow title hopeful. The 31-year-old Kings MMA product went 6-2 on the regional circuit in Brazil, but both of his losses and a win came in a trilogy of fights against Leandro Rodrigues. Eventually, Estrzulas moved on to bigger stages, including King of the Cage, the Resurrection Fighting Alliance, Bellator and the Professional Fighters League. He registered mixed results along the way, scoring wins in KOTC and Bellator while suffering decision losses in the RFA and PFL. His PFL appearance came against UFC veteran Thiago Tavares and ended in a split decision that didnt go his way. Estrzulas, who has a career tally of eight submissions and two knockouts, joined the LFA in 2019 and has thus far recorded two first-round submission victories, both by way of rear-naked choke.

Browne does an excellent job of chaining together punches and kicks, but its primarily a means to set up takedowns for the Brazilian Jiu-Jitsu black belt. The All-American MMA Academy instructor is a strong grappler who also has a collegiate wrestling background. His moniker of Nyquil hints at his affinity for the rear-naked choke, which he has used to secure four of his submission wins at the pro level. He scrambles well, too, and is not content to be kept on his back. However, he can sometimes get sloppy against a fellow grappler and end up spending time on the bottom.

Estrzulas can lull his opponent into a false sense of confidence that leads to their downfall. His LFA foes, Steve Kozola and Dominic Clark, both started strong against the Brazilian before they ended up getting caught in chokes in the first round. The aforementioned Tavares also had to fend off an armbar from Estrzulas after taking the Kings MMA fighter to the ground. Given Brownes tendency to surrender position, Estrzulas should have at least a few chances to lock in a submission even if he is otherwise losing the fight.

Brownes success lies in his ability to remain disciplined, stay in safe positions, and escape any submission holds that Estrzulas locks in. If he ends up overcommitting and losing the upper hand against Estrzulas like he sometimes did against Ben Egli at LFA 87, then this could get ugly. Estrzulas, who is also a BJJ black belt, is quick to jump on any mistake from an opponent and turn it into a fight-ending moment. Estrzulas is also far better with his submissions than Egli, which will make this a tough fight for Browne. Itll be a seesaw battle, but eventually Estrzulas will coax a tapout from his opponent.

Other key bouts: Jose Martinez (11-4) vs. Jacob Rosales (12-6), Kelly DAngelo (4-3) vs. Loveth Young (2-1-1), Michael Stack (4-1) vs. Jordan Mapa (3-2), Thomas Petersen (2-0) vs. Richard Luis (2-2), Josh Quinlan (3-0) vs. Joe Boerschig (6-3), Claire Guthrie (1-1) vs. Nadine Mandiau (1-1)

Brave Combat Federation 46/Krepost Selection 10

Spotlight Fight:Roman Bogatov (10-1) vs. Nurzhan Akishev (11-1)

This weeks theme appears to be collaboration. Brave Combat Federations 46th effort will be conducted in combination with the 10th edition of Krepost Selection. The lineup is a solid one that features such notables as Ali Bagautinov, Leonardo Mafra and Eldar Eldarov. The event also shines a spotlight on Roman Bogatov, who is set to meet Nurzhan Akishev in a 148-pound contest.

Bogatov returns to his homeland following a brief UFC stint in which he lost his lone appearance to Leonardo Santos via unanimous decision at UFC 251. He had previously been an undefeated mainstay under the M-1 Challenge banner, where he reigned as the leagues lightweight champion. Bogatov has collected victories over Rubenilton Pereira, Michel Silva and Mickael Lebout since turning pro in 2016. The 30-year-old has tallied five of his wins by way of submission.

The 27-year-old Akishev has only been competing at the professional level since late 2017, but he has seen action in one more fight than his upcoming opponent. The Kazakh natives first bout took place with the Fight Nights Global organization, but he has bounced around numerous regional companies en route to a perfect mark through seven appearances. Bizon suffered his first and only loss due to a doctors stoppage when he clashed with Nabi Ashurlaev in late 2019. His three most recent victories came in a single night of action for Bushido FC.

Bogatovs UFC release after just one fight might seem surprising at first glance, but his inability to avoid illegal strikes was his undoing. In his fight with Santos, Bogatov was warned after landing two low blows in the third stanza. He then delivered a knee to his downed opponent, which prompted the referee to deduct two points. The point deduction didnt significantly impact the outcome of the contest, which would have been awarded to Santos regardless. However, Bogatovs reputation took a hit as a result. The Brave Combat Federation decided to scoop him up, though, and give him a shot at redemption.

Akishev has already quipped that he wants to have a big family while urging Bogatov to keep the fight clean. The Kazakh fighter, who has eight submission victories and two knockouts, has a lot to prove and a marquee name to do it against. The question is whether this immense leap up in competition will prove to be too much. While he has dispatched a few veterans, Akishevs victims tend to be fighters with five to 10 fights each and modest winning percentages. Bogatov may have come out flat in his UFC bout and only made things worse with his infractions but he was already accustomed to a higher level of competition in his time with M-1. He finished Silva and essentially stopped Lebout. He also tapped out Tahir Abdullaev and Raul Tutarauli, a pair of fighters who held a combined 29-4 mark when they collided with Bogatov.

Bogatov was fortunate to have survived round two in his fight with Santos. The Brazilian had Bogatov reeling, but he just couldnt seal the deal. All of the fouls came in the third round, a frame that began with the Russian bent over in exhaustion. The groin strikes seemed accidental, but the knee to the head was a complete mental lapse by the former M-1 champ. Santos exposed some holes in Bogatovs striking game, but the Russian is a skilled grappler who can cause trouble for anyone on the ground.

Akishev plays right into Bogatovs wheelhouse. The Kazakh upstart will swing wildly on the feet, but hes also a ground technician. Akishevs takedown defense is lacking, and he can be held down and controlled. He likes to scramble and roll for submissions, which has worked well against low-level foes. Hell likely find far less success with this approach against someone like Bogatov. As long as the Russian avoids Akishevs submission attempts from the bottom, he should get the better of the action and perhaps even find a way to submit his less-renowned opponent.

Other key bouts: Eldar Eldarov (12-1) vs. Leonardo Mafra (15-5) for the 165-pound title, Ali Bagautinov (18-7) vs. Oleg Lichkovakha (15-4), Abdysalam Uulu Kubanychiev (16-3) vs. Jahongir Saidjamolov (14-4), Murtaza Talha Ali (1-0) vs. Dmitriy Krivulets (4-1), Zhyrgalbek Chomonov (9-0) vs. Konstantin Erokhin (9-4), Gamzat Khiramagomedov (9-1) vs. Rustam Chsiev (3-2), Alexander Keshtov (9-1) vs. Bair Shtepin (9-3)

Angels Fighting Championship 15: Jae Young Kim (25-13) vs. Jong Hwan Lee (1-1) for the middleweight title

Natal Fight Championship 18: Anderson Queiroz (20-8) vs. Arthur Lima (7-1)

Federal Fight 3: Laura Fontoura (4-0) vs. Tayn Lamounier (3-2) for the womens flyweight title

Last Weeks Scorecard

Ghag couldnt get the predicted TKO finish over Saini, but she did as expected by consistently scoring takedowns and pounding away on her young opponent. Ghag was particularly fond of headlock takedowns that she converted into crucifix-style top positions. Saini was fortunate to survive to the final bell while frequently prone to undefended ground-and-pound flurriesArriaga and Neal engaged in a close affair, but Arriaga just missed out on the predicted decision win. The nod ultimately went Neals way, but the judges were split on the outcomeThere were noBest of the Rest selections in last weeks preview.

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LFA 97, Brave CF 46 and UAE Warriors 15 Preview and Predictions - Combat Press

SEEF DISTRICT._ BRAVE CFs lineup for BRAVE CF 46, the promotions debut event in Russia, already looks stacked. However, another fight will be added to the card, bringing the total number of fights to 13.

An exciting 59 KG matchweight fight has been added to BRAVE CF 46. Kamalov Magomed vs Zokirzhon Khoshimov will be in the preliminaries and will be the second fight of the night.

Magomed from Russia is a Sambo Master and Combat Sambo Champion of Russia. He is 4-1-1 and has never finished in a fight.

Nicknamed the Bullet, the 30-year-old fights on Fight Club Motiv. Zokirzhon Khoshimov is on a 5-fight winning streak. He has only one career decision win as he submitted or KO / TKO all other opponents. A talented fighter, he is a national wrestling champion of Uzbekistan.

BRAVE CF 46 takes place at the WOW Arena (Krasnaya Polyana area), on January 16, in association with Krepost Selection.

The undercard is headlined by a title fight in which super lightweight champion Eldar Eldarov puts his belt on the line against Leonardo Mafra.

The co-main event features MMA legend Ali Bagautinov, who will fight Oleg Lichkovakha. Russian stars like Konstantin Erokhin and Roman Bogatov are also confirmed for action.

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Boxe : Added one more fight to complete the BRAVE CF 46 fight card - Explica

Rolando Dy is set to spend his prime years with BRAVE CF.

The enigmatic Filipino lightweight signed a three-year, five-fight deal with the promotion based in the Middle East.

And for the 2020 BRAVE CF Fighter of the Year and The Hit List Comeback Fighter of the Year, he is just grateful to find a home after an uncertain 2019.

I was getting very proud and confident again. I was slowly forgetting who put me in this position and thats the Lord Jesus Christ, said the second generation fighter.

My career was almost over. I was humbled, but I asked God to give me a second chance and I will preach His Name in front of the world.

After his release from UFC back in 2018, Dy fought five times in 2019. Though going 3-2 for the year, he dropped his last two bouts by way of finishes.

Despite the pandemic, Dy did not stop, eventually being booked by BRAVE last September to go up against Maciek Gierszewski. He won the bout via split decision to earn a title eliminator match against John Brewin in November.

Dy put up one of his finest performances, taking a dominant unanimous decision win that paved the way for a shot at gold and a very good contract.

I would like to thank my God for giving me a good fighting contract in BRAVE Combat Federation.

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Rolando Dy renews ties with BRAVE CF - Tiebreaker Times

The European Commission as approved use of Vertex' Symkevi (tezacaftor/ivacaftor) with Kalydeco (ivacaftor) for eligible children with cystic fibrosis (CF) aged 6-11 years.

The combination therapy offers another treatment option for CF patients who are homozygous for F508del in this age group, and is the only medicine to treat the underlying cause of CF in this patient group.

Specifically, approval covers use of the combination in patients aged six years and older who have two copies of the F508del mutation in the CF transmembrane conductance regulator (CFTR) gene or one copy of the F508del mutation and one copy of one of 14 mutations in the CFTR gene that result in residual CFTR activity: P67L, R117C, L206W, R352Q, A455E, D579G, 711+3AG, S945L, S977F, R1070W, D1152H, 2789+5GA, 3272-26AG, and 3849+10kbCT.

With this approval, children with CF in Europe ages 6 to 11 years with the most common mutation, F508del, have a new treatment option and children with certain residual function mutations will, for the first time, have a treatment option available that addresses the underlying cause of their CF, said Reshma Kewalramani, chief executive and president at Vertex.

In Europe, the medicine is already approved for the treatment of people with CF ages 12 years and older who have either two copies of the F508del mutation in the CFTR gene, or one copy of the F508del mutation and a copy of one of the following 14 mutations in which the CFTR gene results in residual CFTR protein activity: P67L, R117C, L206W, R352Q, A455E, D579G, 711+3AG, S945L, S977F, R1070W, D1152H, 2789+5GA, 3272-26AG, and 3849+10kbCT.

CF accounts for 9,500 hospital admissions and over 100,000 hospital bed days a year. A third of these are used by children under 15.

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Symkevi/Kalydeco cleared for use in young CF patients - PharmaTimes