Category Archives: Alternative Medicine

Alternative Medicines Market is valued at USD 62.33 Billion in 2019 and expected to reach USD 293.56 Billion by 2026 with the CAGR of 19.6% over the forecast period

Alternative Medicines Market: Global Size, Trends, Competitive, Historical & Forecast Analysis, 2020-2026-Rising awareness about the benefits relating to alternative medicines is a key impacting factor driving the growth of the Global Alternative Medicines Market.

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Alternative medicineis the term used for medical products and practices that arent a part of standard care. For examples of alternative medicines include homeopathy, traditional medicine, chiropractic, and acupuncture. It consists of a wide range of health care products, therapies and practices. Alternative practices specialize in stimulating the bodys ability to heal itself via energy alignment, herbal supplementation and other balancing techniques. The medical profession does not support these healing systems as traditional treatment systems. Some of these treatments are accepted to be of value for certain conditions. Herbal medicines include drugs that are derived from plants. Herbal medicines are either used for therapeutic purpose, or as supplements to improve well-being or health. It is available as teas, extracts, powders, capsules, tablets and others. These products are natural and have the ability to cure almost all the types of diseases.

Global Alternative Medicines Market report is segmented on the basis of drug class, dosage form, distribution channel and by region & country level. Based upon drug class, alternative medicines market is classified into herbal products, nutraceutical products, and probiotics. Based upon dosage form, alternative medicines market is classified into tablets, powder, syrup, capsules, teas, extracts, and others. Based upon distribution channel, global alternative medicines market is classified into online pharmacies, retail pharmacies, and hospital pharmacies.

Alternative and complementary medicine comprises application of conventional techniques of medicines such as herbs and other body and mind healing methods mostly based on the belief and faith. Most of the methods employed in alternative medical treatment are not accepted by many regulatory agencies all over the globe. Many regulatory bodies and governments have put up efforts in discovering clinical support for the inclusion into alternative treatments to assist enhance the market and treatment techniques.

Alternative medical treatment comprises non-vitamin, non-mineral, and natural substances. By modality, alternative medicine market can be divided into herbal medicine, homeopathic medicine, acupuncture, naturopathy, ayurvedic medicine, and traditional Chinese medicine, and others. Alternative therapies comprise herbal therapies, magnetic therapy, mud therapy and oil massage therapy, yoga, osteopathic manipulation, deep breathing exercise, and meditation. Alternative medicines and therapies are employed in neurological diseases, chronic diseases, lowering depression & pain, and others.

The regions covered in this alternative medicines market report are North America, Europe, Asia-Pacific and Rest of the World. On the basis of country level, market of alternative medicines is sub divided into U.S., Mexico, Canada, U.K., France, Germany, Italy, China, Japan, India, South East Asia, GCC, Africa, etc.

Alternative medicines market report covers prominent players are The Healing Company Ltd, AYUSH Ayurvedic Pte Ltd, Nordic Nutraceuticals, Columbia Nutritional, Sheng Chang Pharmaceutical Company, Ramamani Iyengar Memorial Yoga Institute, Herb Pharm, John Schumacher Unity Woods Yoga Centre, Pure Encapsulations, LLC and others.

News:

New Findings Indicate Polyphenols from Blueberry and Grape Extracts Prevent Age-Related Memory Decline.

July 25th, 2018; According to Journals of Gerontology, blueberry and grape extracted alternative medicines has improved memory in healthy older adults. The potentially innovative results from researchers at the Institute of Nutrition and Functional Foods (INAF) in Canada and the University of Bordeaux in France demonstrated an improvement of a significant discovery in an era when an estimated 16 million people in the United States are living with and suffering from, cognitive decline. Neurophenol is a polyphenol-rich extract of blueberry and grape that provides a proprietary profile of polyphenols with neuroprotective properties.

Global Alternative MedicinesMarket Dynamics

Rising awareness about the benefits relating to alternative medicines is a key impacting factor driving the growth of the global alternative medicines market. According to the World Health Organization, about 7080% of the world populations trust on nonconventional medicines mainly of herbal sources in their healthcare. In addition, alternative medicines are categorized in various drug classes such as herbal products, nutraceutical products and probiotics. Among all these, nutraceutical products are more popular to enhance growth of the alternative medicines market.

As per NCBI, Nutraceuticals medicines may be used to improve health, prevent chronic diseases, delay the aging process, increase life expectancy, or support the structure or function of the body. Furthermore, increasing side effects and adverse drug reactions due to usage of allopathic medicines will propel growth of markets in forecast period. According to National Center for Biotechnology Information (NCBI), Public interest for the treatment with complementary and alternative medicine is mainly due to the increased side effects in synthetic drugs, high cost of new drugs, microbial resistance, lack of curative treatment for several chronic diseases and emerging diseases, etc.

However, high capital investment and slow healing ability of alternative medicines may hamper the development of alternative medicines market. In spite of that, advance development in healthcare sectors and the increasing investment in research may provide various opportunities for the further growth of alternative medicines market. Governments are additionally presenting good approaches that will enhance the worldwide alternative medicines market during forecast period.

Global Alternative MedicinesMarket Regional Analysis

North America is expected to dominate the global alternative medicines market with the highest share within the forecast period due to the rising awareness among the people about advanced treatment for healthcare in this region. In addition, growing consumption of nutraceutical products to improve health, established healthcare infrastructure and availability of alternative therapies and increase in number of research collaborations are also expected to accelerate the market growth in this region. Furthermore, increasing number of cancer patients is also one of the major factors fostering the market growth in this region.

Cancer is one among the leading causes of death and disease within the U.S. The American Cancer Society (ACS) estimates that roughly 1.7 million new cases of cancer are going to be diagnosed within the U.S. in 2017. According to a survey conducted by the American Society of Clinical Oncology, almost 40% of Americans believe cancer can be cured through alternative therapies alone. As per U.S. National Library of Medicine, In the U.S., the term nutraceutical products are regulated as drugs, food ingredients and dietary supplements and nutraceuticals have received high interests due to potential nutritional and safety profile other than therapeutic capability.

The Asia Pacific is expected to emerge as the fastest-growing regional market over the forecast period owing to the increase in healthcare expenditure, rising awareness about early diagnosis, and availability of effective herbal treatment in emerging countries, such as China and India. Asia Pacific has leading innovation in the ayurvedic treatments by developing and providing transformational treatments that extend and enhance lives. As per NCBI, China has about 95% of Department of Traditional Medicine in their government hospitals.

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Alternative Medicines Market Company Profiles, Segments, Size, Landscape, Demand and Recent Trends, Industry Analysis, Business Outlook, Current and...

Facts & Factors (FnF) published a market research report on AYUSH and Alternative Medicine Market Overview By Trends, Industry Top Manufactures, Size, Industry Growth Analysis & Forecast Till 2026 includes 190+ pages research PDF with TOC including a list of table and figures in its research offerings.

FnF Research presents an updated and Latest Study on AYUSH and Alternative Medicine Market 2020-2026. The report contains market predictions related to market size, revenue, production, CAGR, Consumption, gross margin, price, and other substantial factors. While emphasizing the key driving and restraining forces for this market, the report also offers a complete study of the future trends and developments of the market. The report further elaborates on the micro and macroeconomic aspects including the socio-political landscape that is anticipated to shape the demand of the AYUSH and Alternative Medicine market during the forecast period (2020-2029).

The historical and forecast information provided in the report span between 2018 and 2026. The report provides detailed volume analysis and region-wise market size analysis of the market.

According to the research report, Global breathalyzer market is expected to grow at a CAGR of 7.5% and is anticipated to reach around USD 1070.01 Million by 2026. Breathalyzer is a tool to measure the blood alcohol concentration of the breath sample. This system is commonly used by different industries for the monitoring of alcohol and substance addiction.

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AYUSH and Alternative Medicine Market by Top Manufacturers (2020-2026)

Sydler India Pvt Ltd

SBL Mathur

Patanjali

Hootone Remedies

Himalaya Wellness

Hamdard

GR Herbals

Ganga Pharmaceuticals

Dabur India

Baidyanath

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Industry study presents the global AYUSH and Alternative Medicine market size, historical breakdown data (2014-2019), and forecast (2020-2026). Production, revenue, and market share by key vendors, key regions, and type; The consumption of AYUSH and Alternative Medicine market in terms of volume is also provided for major countries (or regions), and for each application and product at the global level.

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In this study, the years considered to estimate the market size of AYUSH and Alternative Medicine Market:

Geographically,this report is segmented into severalkey regions, with sales, revenue, market share, and growth rate of AYUSH and Alternative Medicine in these regions, from 2020 to 2026, covering

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Segmentation

As discussed earlier, there is segmentation in theAYUSH and Alternative Medicine Marketreport, to improve the accuracy and make it easier to collect data. The categories which are the dividing factors in the industry are distribution channels, application, and product or service type. With this level of segmentation, it becomes easier to analyze and understand the AYUSH and Alternative Medicine Market. At the same time, there is an emphasis on which type of consumers become the customers in this industry. When it comes to distribution channels, the AYUSH and Alternative Medicine Market report looks at the different techniques of circulation of the product or service.

Regional Overview

In this part of theAYUSH and Alternative Medicine Marketreport, we will be taking a look at the geographical areas and the role they play in contributing to the growth of this line of business. The areas of interest in this document are as follows the Middle East and Africa, South and North America, Europe, and the Asia Pacific. From the AYUSH and Alternative Medicine Market report, it becomes clear which region is the largest contributor.

Latest Industry News

From thisAYUSH and Alternative Medicine Marketreport, the reader will also get to learn about the latest developments in the industry. The reason is that these products or services have the potential to disrupt this line of business. If there is information about company acquisitions or mergers, this information will also be available in this portion of the AYUSH and Alternative Medicine Market report.

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AYUSH and Alternative Medicine Market Insights 2020: Top Impacting Factors, Growth Analysis and Industry Predictions And Outlook 2026 The Courier -...

Government initiatives play a major role in propelling the demand for integrative health and complementary medicine practices by strengthening targeted expenditure, setting up government facilities, and releasing guidelines to ensure appropriate usage of complementary and alternative medicine (CAM). Regulatory bodies are also focusing on the promotion of medical tourism as it attracts people from other places and helps them seek world-class alternative medical treatment. For instance, Indian regulatory authorities have made significant investments in the development and standardization of alternative medical facilities in some of the states.

Conventional and Alternative Pain Treatment Marketresearch is an intelligence report with meticulous efforts undertaken to study the right and valuable information. The data which has been looked upon is done considering both, the existing top players and the upcoming competitors.

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Conventional and Alternative Pain Treatment Market is growing at a 22.03% CAGR during the forecast period 2021-2027. The increasing interest of the individuals in this industry is that the major reason for the expansion of this market.

Business strategies of the Conventional and Alternative Pain Treatment key players and the new entering market industries are studied in detail. Well explained SWOT analysis, revenue share and contact information are shared in this report analysis. It also provides market information in terms of development and its capacities.

Top Players Are: Abbott Laboratories, Baxter International, Eli Lilly & Co., GlaxoSmithKline, and Johnson & Johnson

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Various factors are responsible for the markets growth trajectory, which are studied at length in the report. In addition, the report lists down the restraints that are posing threat to the global Conventional and Alternative Pain Treatment market. It also gauges the bargaining power of suppliers and buyers, threat from new entrants and product substitute, and the degree of competition prevailing in the market. The influence of the latest government guidelines is also analyzed in detail in the report. It studies the Conventional and Alternative Pain Treatment markets trajectory between forecast periods.

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The cost analysis of the Global Conventional and Alternative Pain Treatment Market has been performed while keeping in view manufacturing expenses, labor cost, and raw materials and their market concentration rate, suppliers, and price trend. Other factors such as Supply chain, downstream buyers, and sourcing strategy have been assessed to provide a complete and in-depth view of the market. Buyers of the report will also be exposed to a study on market positioning with factors such as target client, brand strategy, and price strategy taken into consideration.

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Global Conventional and Alternative Pain Treatment Market Report 2021 Growth, Trend and Forecast to 2027

Chapter 1 Conventional and Alternative Pain Treatment Market Overview

Chapter 2 Global Economic Impact on Conventional and Alternative Pain Treatment Industry

Chapter 3 Global Conventional and Alternative Pain Treatment Market Competition by Manufacturers

Chapter 4 Global Production, Revenue (Value) by Region (2014-2021)

Chapter 5 Global Supply (Production), Consumption, Export, Import by Regions (2014-2021)

Chapter 6 Global Production, Revenue (Value), Price Trend by Type

Chapter 7 Global Market Analysis by Application

Chapter 8 Manufacturing Cost Analysis

Chapter 9 Industrial Chain, Sourcing Strategy and Downstream Buyers

Chapter 10 Marketing Strategy Analysis, Distributors/Traders

Chapter 11 Market Effect Factors Analysis

Chapter 12 Global Conventional and Alternative Pain Treatment Market Forecast (2021-2027)

Chapter 13 Appendix

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Photo courtesy of True Nature Healing ArtsHow to Live a Better Life Right Now

Day spas are great, but long-term health and happiness require so much more. Here are seven places that offer distinctive, purposeful approaches to soothing body, mind, and spirit.

Has there been a year in recent memory when its been harder to feel and be well? Social and physical restrictions, instituted to keep us healthy, couldnt help but also make us feel so, so bad. This makes it all the more important that in 2021, we define wellness broadlynot just a back massage and cucumber slices over the eyes, but a practice of living that treats the self, the community, and the climate with care and respect. Whether theyre a hundred-person operation or a one-woman show, whether they involve ancestral practice or innovative new inventions, the following wellness experiences aspire to that definition.

Note: 5280 encourages you to do your own research and consider consulting with your doctor before engaging in alternative medicine practices.

Why its special: From muscle work to moon reiki to psychedelic coaching and more, Nurture might fairly be called Denvers wellness mecca. Over 60 independent health practitioners and retailers operate out of Nurtures open-concept building, which also features a cafe, bar, sauna, organic hair salon, and Himalayan salt room. Plan a visit ahead of timeperhaps to see Georgia Grey, who offers holistic nutrition coaching for those who, like her, struggle with autoimmune conditionsor explore the offerings at your leisure. You can even drop off your kids at Nurturelings, a childcare service with mindful programming run by Rebecca Kanov of Arts & Minds. Ultimately, co-founder Peter Strauss wants the space to help you be a true, non-compartmentalized version of yourself.

Whats new in 2021: Nurture just launched a new booking platform, complete with gift certificates that can be spent across almost all the stores and services in the building. Theyre also in the process of launching a corporate wellness program for Colorado businesses.

If you go: 2949 Federal Blvd.; Prices vary between practitioners; Nurtures spaces are open to the public.

Why its special: Medical clinician Nancy Rae Kochis (Apache Nation of Colorado, Carlana Tribe, Mountain Buffalo Band) orchestrates a network of indigenous health workers in rural communities and reservation areas across seven states. The intention behind our medicine is justice, Kochis says. That survivors get help, and that perpetrators and their descendants also find peace. Anyone, including non-Natives, can sign up for telehealth appointments on their client portal to learn about and involve themselves in Herbal Gardens lifestyle health practices, which combine Western medicine with two millenia-worth of botanical and spiritual Apache teachings. Herbal Gardens, a nonprofit organization, then takes earnings from these classes, as well as grants from organizations like the Chinook Fund, and uses them to care for Native people most in hope (a term Kochis prefers to in need) across the West. This looks something like Kochis reviewing medical records for someone who needed retinal reattachments, speaking with a Lakota woman about treatment options, and coordinating a grocery drop-off for a diabetic woman soon to return from surgery.

Whats new in 2021: Most of Herbal Gardens work with non-Natives is virtual, but Kochis is beginning to host in-person workshops in Hartsel, Colorado and elsewhere this spring.

If you go: A holistic health assessment is $95; a wellness coaching session is $125; Herbal Gardens uses the money from these outward-facing programs to provide health services to indigenous communities free of charge.

Why its special: Tasha Madison opened the only full-day, Black-owned spa in Aurora on February 1 last year. Less than two months later, though, On The Go had to close because of the pandemic. Theyve since reopened with a wide array of mix-and-match spa packages. To help with migraines and fatigue, Madison recommends the oxygen therapy treatment combined with essential oils like eucalyptus and bergamot; the facials and hot stone massages are also quite popular. She prides herself on the cool, relaxing ambience of the lounge, which always has complimentary wine and fresh tea available to sip. And when you leave, grab a bottle of On The Gos essential skincare productsa cleanser, a toner, a moisturizer, and a sunscreento take the guesswork out of your skin health.

Whats new in 2021: The pandemic initially dashed Madisons hopes to host spa parties for bridal showers, but On The Go is now able and eager to accommodate them.

If you go: 2295 S Chambers Rd, Unit I, Aurora; The magnesium foot detox is $65; thirty minutes of oxygen therapy is $25; day spa packages start at $175.

Why its special: From time to time in the wellness world, you might run into practitioners who take themselves too seriouslybut not Curious Sunshines Sarah Iverson, who wants to create a community that allows you to be goofy. Iverson synthesizes influences as diverse as ecopsychology, visual art, and Afropunk to create what she calls quirkshops: collaborative sessions of mindfulness, curiosity, and play designed especially for people of color. (She often partners with groups like Black Womens Alliance and Soul 2 Soul Sisters.) The quirkshops are on pause during the pandemic, but when they resume, attendees can expect to blow bubbles, meditate outdoors, and write group poetry. In the meantime, you can complete puzzles and emotional self-check-ups in Black In Color: A Melanated Activity Guide to Liberation, Iversons wellness activity book.

Whats new in 2021: Iverson is planning an April release of a new online wellness course with a series of modules all about tapping into our inner sunshine.

If you go: Hourlong quirkshops vary in price; Black in Color costs $15.

Why its special: Even though American women experience mental health challenges like depression and anxiety at roughly twice the rate of men, according to a 2017 report by the American Psychiatric Association, amid the responsibilities of work and home life, they seek out mental health specialists less often than their counterparts. With this trend in mind, psychologist and professor Dr. Nikki Jones founded her telehealth womens wellness collective, Rise, in November 2019 to serve clients who could make time to get help during their lunch break or while their kids nap. Rise was conveniently well-situated to adapt to the new, remote normalJones and her Grand Junctionbased team now serve clients across the state and the country. Rises premier offering is its TheraCoaching program, which gives clients virtual, one-on-one sessions with both a licensed psychologist and a life or mindfulness coach. After all, the internal changes necessary for self-actualization are rarely separable from the external onesyou heal from trauma as you change careers, you try to rescript negative self-talk as you adapt to a new exercise routine.

Whats new in 2021: Group workshops for women, starting with but not limited to workplace dynamics, that Jones hopes will be held in-person.

If you go: TheraCoaching sessions start at $100.

Why its special: Natnicha Aey Lappichate couldnt find traditional Thai massages practiced by Thai people when she moved to Colorado in the mid-2000s. So she returned to her native Bangkok to study the art and craft of delicate and deliberate stretching, twisting, pulling, and pushing along a bodys ten energy lineswhat she calls lazy yoga. At Siam Sensation, Lappichate has been practicing, teaching, and refining these techniques for over a decade. Expect to be soothed not just by a masseuses hands and feet but also by time-honored accoutrements like wrapped Thai fabrics and steam-heated herbal balls. The Tok Sen massage, which involves tapping a two-pronged wooden mallet to break down fascia and help with nerve pain, is particularly beloved. Lappichate hopes her customers dont think of massage as an out-of-the-ordinary luxury but as a regular, integral element of their everyday selfcare.

Whats new in 2021: A bamboo roller massage intended to reach ones deep tissue.

If you go: Located at 5330 Manhattan Cir., Suite G, Boulder, and 16 Mountain View Ave., Suite 102, Longmont; $190 for a two-hour Tok Sen massage, $85 for a one-hour foot reflexology massage.

Why its special: What began in 2007 as a 500-square-foot space for meditation and yoga has ballooned into a multi-acre campus dedicated to practically all forms of personal growth. Theres a peace garden, an organic cafe that serves produce grown in the peace garden, a Kiva event center that seats 100, an apothecary, outdoor labyrinth, and a spa specializing in ayurvedic treatments. Locals can drop by just to have a cup of coffee ensconced in gorgeous architecture while out-of-towners can drive up for themed retreats. According to co-founder Eaden Shantay, the four petals of the lotus flower on True Nature Healing Arts logo represent the sites four core values: inspiration, connection, self-discovery, and service.

Whats new in 2021: To hybridize its business model, the center is scaling up its virtual class offerings and online boutique.

If you go: 100 N 3rd Street, Carbondale; Drop-in yoga classes are $18; spa treatments start at $125; retreats start at $220; the peace garden is free.

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Where to Find Unique Wellness Experiences in Colorado - 5280 | The Denver Magazine

When Jo Anne Schatz, 69, talks about the latest treatment she received for her endometrial cancer, she describes it as an eraser.

It was amazing, Schatz says. It just wiped my cancer out.

The drug, Keytruda (pembrolizumab), is a type of cancer treatment called immunotherapy, designed to harness a persons immune system to identify and destroy the cancer. It is just one of the targeted treatments approved by the Food and Drug Administration (FDA) for or being developed for the treatment of endometrial cancer.

Unlike traditional chemotherapy, which acts against cancer cells and healthy cells alike, targeted treatments are aimed at specific aspects of the cancer cells.

Keytruda hitting its target is what Schatz credits with saving her life.

Schatz, a former addiction specialist from Philadelphia, received a diagnosis of endometrial cancer in May 2015 after experiencing unexpected vaginal bleeding. She had never heard of the disease.

My primary care doctor told me to contact my gynecologist; within two weeks, I was seeing a specialist at Fox Chase Cancer Center and headed in for a complete hysterectomy, Schatz says.

Endometrial cancer is a disease in which cancer cells form inside the lining of the endometrium, or uterus. Vaginal bleeding and pelvic pain are common symptoms.

Endometrial cancer is the most common of all gynecological cancers in the United States, says Dr. Christina S. Chu, professor in the Department of Surgical Oncology at Fox Chase Cancer Center in Philadelphia. Fortunately, the vast majority of endometrial cancers can be treated surgically with the removal of the uterus, ovaries, fallopian tubes and cervix. Most are cured with this surgery plus or minus radiation.

Some patients 13% who receive a diagnosis of endometrial cancer, however, will have their disease recur. After surgery, Schatz underwent several rounds of radiation and chemotherapy to destroy any remaining cancer cells. After a brief remission, her cancer recurred, metastasizing to the peritoneal lining, and her physicians began to look for more targeted treatment options.

When we started to get down to the genomic levels of these tumors, we realized that just because some endometrial cancers may look (similar) under the microscope, they may still behave biologically different based on genomic signature, says Dr. Emily M. Ko, assistant professor of obstetrics and gynecology at Pennsylvania Hospital of Penn Medicine in Philadelphia. Based on that genomic signature, there may be biologic pathways that we can target.

That is what happened to Schatz, who was told that her type of endometrial cancer had a genetic component called MSI-high.

MSI stands for microsatellite instability. When disease is MSI-high, the cancer cells have a high number of mutations within microsatellites, which are short, repeated sequences of the DNA. These signify abnormalities in DNA repair, which can be targeted with certain drugs.

In 2017, the FDA approved Keytruda for use as a treatment for any solid tumor that was MSI-high, had progressed after prior treatment and had no satisfactory alternative treatment options.

This was important for patients with endometrial cancer because (approximately) 30% of patients with endometrial cancer will have tumors that are MSI-high, explains Dr. Shannon N. Westin, associate professor in the Department of Gynecologic Oncology and Reproductive Medicine at The University of Texas MD Anderson Cancer Center in Houston.

One study evaluating the use of Keytruda in patients with MSI-high tumors showed that among a small group of women with endometrial cancers, more than half saw their tumor respond to the treatment, and the majority had at least some clinical benefit.

A larger proportion of patients with endometrial cancer will have microsatellite-stable disease, Westin says. For those patients, there is a newer FDA-approved targeted therapy combining Keytruda with Lenvima (lenvatinib).

Indeed, in late 2019, the FDA approved the immuno- therapy Keytruda with Lenvima for patients with endo- metrial cancer that is not MSI-high and whose disease has come back after prior chemotherapy. Lenvima is a multiple-receptor tyrosine kinase inhibitor. The drug works by blocking the action of abnormally activated proteins that signals cancer cells to multiply. A study of this combination showed that approximately one-third of endometrial tumors responded.

Finally, some patients with endometrial cancer may qualify for treatment with a drug targeting NTRK gene fusions, which are estimated to occur in only a small percentage of endometrial cancers. Rozlytrek (entrectinib) and Vitrakvi (larotrectinib) are approved for adults who have solid tumors with this specific genetic alteration.

Not every endometrial cancer that comes back or spreads will have one of the characteristics to qualify for the currently available targeted treatments. These women may want to ask their physicians about potential alternatives, Ko says.

Kim Bryant, 61, a former special education teacher from Texas, did just that when she was told in May 2019 that her endometrial cancer had spread. After receiving her diagnosis in March 2016, Bryant initially underwent surgery and radiation for the cancer. After its first recurrence a year later, she had additional surgery followed by radiation and chemotherapy.

At that point, my local oncologist said he had done all he could and referred me to MD Anderson, Bryant says. I was given a choice between two trials. I was enrolled in one for about a year and my cancer progressed. I have had more success with the second trial.

The second clinical trial is testing a three-drug combination of the hormone therapy Femara (letrozole); Afinitor (everolimus), a drug designed to target a protein called mTOR that promotes cell growth; and Kisqali (ribociclib), a CDK 4/6 inhibitor that is designed to interrupt the cell cycle that drives growth of cancer cells.

CDK 4/6 inhibitors have been studied in breast cancer and are thought to potentially be synergistic when used with other hormonal drugs, Ko says.

For her first clinical trial, Bryant had been making a four- hour drive once a week from Dallas to Houston to receive treatment. On the current trial, all three drugs are oral and can be taken at home.

All three oral treatments (are) so much easier because there are no infusions, Bryant says. I only have to go down once every three months for bloodwork and other testing.

Bryant remains on treatment and says that, so far, the cancer is responding well.

In addition to mTOR and CDK 4/6 inhibitors, clinical trials are also testing a class of drugs that inhibit poly (ADP-ribose) polymerase more commonly known as PARP inhibitors. This class of drugs is approved for certain breast and ovarian cancers that have an inherited mutation in the BRCA gene

or have a certain genomic instability called homologous recombination deficiency (HRD), a type of DNA repair defect.

There are a number of trials exploring these drugs alone or in combination with other targeted agents to see if there is activity in endometrial cancer, Westin says. Probably about 20% of endometrial cancers have mutations in BRCA or other abnormalities in HRD pathway members, but there may be other abnormalities in endometrial cancer that predict benefit, so none of the trials (is) being selective.

There are also trials exploring other immunotherapy drugs that target a protein called PD-1 or PD-L1, immunotherapy drugs in combination with chemotherapy or other targeted agents, and agents targeted against other disease pathways such as the PI3K or MEK pathways, Westin says.

Right now, these targeted therapies are considered second- line treatments given after a first disease recurrence because they are not as effective as primary chemotherapy for most patients, according to Chu.

Trials are ongoing to test targeted therapies in combination with chemotherapy in the first-line setting, though, Chu says.

There have not been any completed clinical trials yet comparing the standard chemotherapy with these new targeted treatments, but they are in progress, according to Ko.

What we are learning is that perhaps side effect profiles may be better in targeted treatment, meaning it may be worthwhile to consider an alternative targeted therapy up front in treatment rather than saving it for down the road, explains Ko.

For example, immunotherapy drugs such Keytruda do not have the traditional side effects seen with chemotherapy, such as hair loss, nausea or vomiting. Because the drug works by attempting to stimulate the immune system, many of the side effects seen with Keytruda are related to the immune system, Chu says. Similarly, side effects seen with Lenvima, which works by affecting blood vessels, can be related to a patients blood vessels, such as high blood pressure.

Schatz says that during her treatment with Keytruda, she experienced muscle aches, pains and fatigue. Other common side effects associated with Keytruda include headache, fever, skin rash, constipation, loss of appetite and diarrhea.

On chemotherapy, I was often sick for a full week, then a little better before preparing to go back for another treatment, Schatz says. On the trial, I was able to cook and care for myself and establish a routine.

Bryant says that side effects during her most recent clinical trial also have been tolerable.

I have had some decrease in appetite and some fatigue, but not enough that it keeps me from doing what I want to do, Bryant says. It has only slowed me down some.

Many of the side effects related to targeted therapies can be managed easily if caught early, Westin says.

This takes good communications between a patient and their health care team and preparation so that a patient knows what to look for, Westin says.

In addition to a patients tumor having the right target, the health care team will consider these possible side effects in their decision on whether a patient might qualify for treatment with a targeted therapy.

We look at the best data we have available, the tumor characteristics and the overall health of each patient to decide if a targeted therapy is best, Ko says.

Schatz credits much of her progress not only to targeted therapy but also to advocating for herself and her treatment. She had one doctor who encouraged her to continue treatment, whereas another told her to stop. Since stopping treatment with Keytruda, Schatz has follow-up scans every four months, as well as other regular monitoring. I am also healthier, she says. I am on a cancer-fighting plant-based diet. I take it one day at a time, but I am grateful to be alive and can feel my creativity coming back.

Bryant, too, has been able to maintain an upbeat, glass-half-full attitude throughout her cancer journey, she says.

I have surrounded myself with my faith, family and friends, she says.

Westin applauds patients such as Schatz and Bryant for raising their voices and sharing their stories about endometrial cancer.

Other tumor types get more attention, but endometrial cancer is one of the only cancer types where the incidence is growing, Westin says. A lot of women with endometrial cancer will be cured, but we have to be aware of their sisters in diagnosis who do not do as well and together raise our voices to shine more light on this problem. Hopefully that will allow us to get more funding and more companies interested in exploring new agents to treat endometrial cancer.

For more news on cancer updates, research and education, dont forget tosubscribe to CUREs newsletters here.

Link:

Targeted Therapies Take Aim at Endometrial Cancer - Curetoday.com - Curetoday.com

Orestis Tsonis,1 Fani Gkrozou,2 Zoi Barmpalia,1 Annamaria Makopoulou,3 Vassiliki Siafaka4

1Department of Obstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, Greece; 2Department of Obstetrics and Gynaecology, University Hospitals of Birmingham, Birmingham, UK; 3School of Psychology, College of Human Sciences, Bangor University, Bangor, Wales, UK; 4Department of Speech and Language Therapy, School of Health Sciences, University of Ioannina, Ioannina, Greece

Correspondence: Orestis TsonisSenior Registrar in Obstetrics and Gynaecology, Department of Obstetrics and Gynaecology, University Hospital of Ioannina, Stavrou Niarchou Avenue, Ioannina, 45500, GreeceTel +306986620604Email orestis.tsonis@gmail.com

Objective: This narrative review aims to identify alternative ways to improve the symptoms of primary dysmenorrhea (PD).Background: PD refers to endometrial painful cramps during the premenstrual period. This condition affects a lot of women worldwide and is accompanied with absenteeism and high economic costs, thus, risk-free, and effective therapeutic approaches are needed. Pharmacological agents such as non-steroidal anti-inflammatory drugs (NSAIDs) and oral contraceptive pills (OCPs), which are widely prescribed for these women, demonstrate adequate efficacy in alleviating pain and discomfort. The long natural course of the disease dictates remedies that focus on lifestyle changes and on improvement of Quality-of-Life (QoL) for women suffering with PD.Materials and Methods: Five major search engines, namely MEDLINE, PubMed, EMBASE, and Cochrane Library were searched for articles published prior to October 2020 focused in PD. A total of 74 paper were included.Discussion: Physical activity, for instance yoga, aromatherapy massage, and other forms of relaxation, vitamins and dietary changes, acupressure and acupuncture,a and some psychological interventions are just few of the proposed health behavior targeted approaches in cases of PD. This review focuses on lifestyle changes and alternative methods that could potentially result in minimizing symptoms of PD and in improving overall QoL for these patients, by providing current scientific evidence on their efficacy.Conclusion: Complementary and alternative medicine practices (CAM) are widely accepted by women. International literature provides controversial scientific evidence, thus further studies need to be conducted in order to prove or disregard their efficacy in cases of PD.

Keywords: primary dysmenorrhea, quality-of-life, therapy, complementary and alternative medicine, pain relief

Primary dysmenorrhea (PD) is recurrent menstrual cramps during the menstrual period and painful menses that are not associated with any other obvious medical pathology, with an indigenous sensation of pain, a few days prior to menstruation, that normally persists approximately, 4872 hours after the onset of menstrual bleeding.1 PD is considered the commonest complaint for adolescents as well as, women of reproductive age, and this condition manifests through a wide variety of symptoms, either physical or affective,2 such as back pain, abdominal and pelvic pain, headaches, migraines, insomnia, nausea, dizziness, fatigue, sweating, cramps, irritability, depression, and emotional instability, with a negative impact on overall Quality-of-Life (QoL) compared to healthy women.1,3 International literature lacks consistent scientific evidence with regards to PDs prevalence, reporting various trends of between 4595% due to different methods of measurements and definitions used worldwide.1,4

This condition is postulated to arise from an abundant production of indigenous prostaglandins that result in an irregular pattern of endometrial contractions along with a decrease in the overall endometrial blood supply. Current medical agents against PD have been well established, such as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) and COPs (Combined Oral Contraceptives), and act in a way that minimizes the production of prostaglandins. Unfortunately, these drugs come with unpleasant side-effects, such as nausea, vomiting, GI bleeding, acne, and asthma, to name a few, especially when administered for long-term use.3

The long physical course of PD demands therapeutic approaches that regard complementary medications and a holistic management for these patients without jeopardizing patients overall QoL. Patients ought to adopt novel lifestyle targeted habits with regards to nutrition, physical activity, and complementary practices that minimize the effects of PD while improving QoL.3 That said, absenteeism at school and work, which is clearly linked with increased financial cost for society, make this lifestyle targeted change imperative for these patients in order to establish an approach that could relieve individuals suffering from PD by maintaining highest therapeutic efficacy along with improved QoL.

Over the last decades researchers have studied health behaviors change in a wide variety of conditions. Achieving a change in a persons health behaviors is a difficult and complex process. Consequently, the deviations vary and may have a significant impact on the individuals health and on the health system. Theories for understanding and enhancing health beliefs (eg, Health Belief Model, Health Promotion Model, and Theory of Reasoned Action) argue that it is relatively easier to achieve onset, than to maintain it in the long-term. The pattern of health behavior change seems to be common, with high recurrence rates varying early after the change. In addition, social factors influence behavior, with an ambiguous impact on both initiating and maintaining health behavior change.5

In the literature, a plethora of complementary and alternative medicine (CAM) practices and medications have been suggested, but the efficacy of these suggestions remain still controversial.6 Similarly as in the case of post-menopausal symptoms, neutraceutical alternates have been suggested. Women that refuse hormonal replacement treatment (HRT) can potentially use Isoflavones, herbal derivatives, vitamins, and other compounds such as polyphenols.7 Over the last 10 years, CAM therapies have been proposed, especially in regions of Africa and Asia where traditional medicine remains trusted by the majority of patients, therefore, approximately all studies conducted regarding CAM efficacy originated from these countries.2,8,9 Physical activity, for instance yoga, aromatherapy, psychotherapy, and other forms of relaxation, vitamins and dietary changes, acupressure and acupuncture are just few of the proposed lifestyle targeted therapies in cases of PD.3 This review focuses on lifestyle changes that could potentially result in minimizing symptoms of PD and in improving overall QoL for these patients, by providing current scientific evidence on their efficacy.

Five major search engines, namely MEDLINE, PubMed, EMBASE, and Cochrane Library, were searched for articles published prior to October 2020 that matched any combination of the following key words: [primary dysmenorrhea] OR [dysmenorrhea] OR [menstrual pain] AND [life-style] OR [alternative medicine] OR [complementary medicine] OR [diet] OR [physical activity] OR [herbs] OR [acupressure] OR [acupuncture] OR [aromatherapy] OR [heat therapy] AND [emotional support] AND [psychological support] AND [psychotherapy]. Only scientific papers in English were included. A total of 74 papers were included.

This paper presents the results of a narrative review. The review focuses on lifestyle modifications that alleviate painful symptoms in patients suffering from Primary Dysmenorrhea. All complementary and alternative therapeutic approaches focusing on lifestyle changes, that are supported by valid scientific evidence, are presented.

These are nutrition, physical activity, Body Mass Index (BMI), herbs, essential oils, and medical plants. In addition, less explored approaches, the relevant sociocultural issues, and psychological aspects are mentioned, in order to present all the available information in the literature. Acupressure, acupuncture, and reflexology are also mentioned, since these methods are alternative types of medicine which represent a different lifestyle and encourage people to differ their everyday life and habits. They are based on a different philosophy and approach than the general western lifestyle.

Papers addressing secondary dysmenorrhea or other evident pathologies that could cause menstrual pain, such as endometriosis, have been excluded.

Maintaining a healthy diet containing dairy products and fibre has been postulated to positively act against PD symptoms.1 Salt and animal fat restrictions have also been proposed as effective for this condition.10 Interestingly, skipping breakfast is linked with PD, while overall low calorie intake has been found to be a risk factor for this condition.1 A possible pathophysiologic explanation is that a normal BMI is associated with regular ovulation and menses, whereas extreme BMIs lead to a prostaglandin abundance that causes painful menstruation. Scientific evidence remains inconclusive, and further studies need to be conducted in order to check the validity of such hypotheses.

Warm beverages and food were found to be preferred by women suffering from PD in order to alleviate their symptoms. Moreover, women with PD with a family history of PD in their mothers were more likely to adopt a healthier nutrition plan, suggesting that PD awareness might increase lifestyle focused approaches into the management of Primary Dysmenorrhea.11 Reduction in beverages containing caffeine was also a nutritional modality that was adopted by patients with the disease, as well as meat restriction, in order to minimize the unpleasant impact of PD in their QoL.4

A 2016 Cochrane review study revealed the insufficiency of scientific evidence so far, and, while vitamin E supplements are not considered effective, fish oil and vitamin B1 evidence is very limited to safely draw a conclusion about their use in cases of PD.12

With regards to body fitness, maintaining a stable Body Mass Index (BMI), between 1924.9 kg/m2, is associated with lower rates of PD, whereas weight extremes exacerbate painful symptoms in patients with PD, as a recent Chinese cross-sectional study suggests.1

Yoga is considered an excellent tool in reducing pain duration and severity in cases of PD.13 More specifically, women with PD are instructed to follow a 20-minute session daily during their luteal phase, emphasizing in cobra, cat, and fish postures to alleviate their painful symptoms.14 Yoga intervention was associated with improved QoL and decreased physical pain and discomfort.15,16 More specifically, patients with PD who trained by yoga for at least 6 months were more likely to reporthigher levels of energy and concentration, as well as lower occurrence of sleep disturbances, insomnia, and confusion. These patients demonstrated stress relief, more social relationships, and higher work capacity by participating actively in their daily activities.15

Other forms of physical activity, such as isometric exercise and stretching, running, Kegel exercises, and relaxation postures have also been proposed to release pain and discomfort in dysmenorrhea, when performed regularly.1719 It seems that 50 minutes of exercise at least 3-times per week has a positive impact in women suffering from painful menses. Physical activity is an excellent tool in maintaining a healthy body, normal cardiovascular function, and improved emotional balance, while physical inactivity is considered the fourth most important risk factor of mortality worldwide as it is strongly linked with cancer, diabetes, and cardiovascular disease.18 Aerobic activity results in an indigenous release of opioids that improve overall QoL and reduce pain sensitivity in women with PD.18

A wide variety of herbs has been suggested to improve symptoms in patients suffering from PD. Chamomile, fennel, cinnamon, and aloe vera are only a few of the herbal regimens that are proposed to treat the severity of symptoms by their anti-inflammatory and anti-spasmodic properties.3

Chamomile is widely used in European traditional medicine for its analgesic and anti-inflammatory effects. A number of studies have suggested its action on the uterus by increasing blood flow and minimizing pain symptoms for patients with PD. Chamomile has been proven to treat cases of migraines and muscle pain, thus, its potential therapeutic effect on dysmenorrhea is quite possible. Matricaria chamomilla minimizes mood swings, anger, and depression, as well as pain perceived severity, fatigue, and lethargy compared to control group patients that received no medication.12,20

Fennel originated by Umbelliferae contains anethole, fenchone, and limonene, which act as dopamine-like agents.21 Anethole blocks dopamine receptors and inhibits endometrial contractions caused mainly by prostaglandins.3 Thus, fennel supplements decrease pain perception in these patients. Along with the analgesic properties of this plant, mainly used as a herb in Chinese culture, the lack of side-effects during its use make it ideal therapy in cases of PD, where long-term treatment is required. Foeniculum vulgar Mill, publicly known as fennel, lowers pain scores in patients with PD and improves overall QoL.12,22

Zataria multiflora is another commonly used herb in patients suffering from PD due to its inhibitory effect against prostaglandin production. More specifically, thymol, as the main ingredient of this plant, blocks calcium channels that are responsible for endometrial cramps.12 The effect of Zataria multiflora oil has been suggested to minimize the severity of pain in women with PD as well as to shorten the duration of pain.12,23,24

Other herbs, such as ginger (Zingiber officinale),25 Valeriana officinalis,21 Cinnamomum (cinnamon),26 and lavender oil,27 provide pain intensity reduction equal to pharmacological agents, such as mefenamic acid, although their exact therapeutic mechanism remains unclear.20,2836 A 2016 Cochrane 2016 emphasized the existence of limited evidence so far in herbal medicine and proposed further RCTs in order to assess the overall effect of herbal medicine in cases of PD.12 Research in the international literature shows dozens of herbal plants used in PD with promising results. Thus, well-designed RCTs should be employed in order to provide valid scientific evidence on their efficacy since, so far, the findings are inconsistent.

In cases of PD, neuromuscular manipulation and acupressure have been adopted by many patients who consistently report a meaningful improvement in pain intensity and duration.37 Although of low quality, the majority of studies report the effectiveness of this CAM modality in patients suffering from PD.38 Many sites have been proposed, while auricular acupressure gained much popularity due to the simplicity of self-therapy.38 Acupressure by trained personneldemonstrates higher rates of efficacy among studies,39,40 but self-administered acupressure remains a risk-free and efficient CAM modality in patients with dysmenorrhea.39,41 The effect of acupressure has also been proven in cases of obesity, smoking cessation, acne, and emotional stability, but the exact mechanism of action remains unclear.42 In cases of PD though, patients who received acupressure were found to have increased uterine blood flow that potentially minimized the pain and discomfort experienced during menses.38 Many patients adopt manipulative therapy as an adjunct therapeutic tool in the management of PD.43 A recent RCT that investigates the effect of acupressure in PD concluded that manipulating menstrual pain zones during 1015 sessions provided pain relief for patients with PD along with high rates of satisfaction.44 The exact therapeutic duration of each manipulation though needs to be further explored, as international literature fails to present long-term reduction of painful symptoms for these patients.45,46

Many studies so far have praised the effect of acupuncture in minimizing the pain of PD.39,47,48 The evidence shows that acupuncture reached higher overall improvement of pain in these patients compared to NSAIDs monotherapy.19,47,49 Unfortunately, despite the success noted by the vast majority of studies on the subject, the Cochrane Database of Systematic Review found very low quality of evidence, mainly attributed to risk of bias, poor reporting, inconsistency, and risk of publication bias.47 In terms of QoL in women with PD that receive acupuncture alternative therapy, the evidence shows improved physical function, mental health, bodily pain, vitality, social function, and emotional role, while no adverse outcomes by this intervention were reported.3,50 Nevertheless, authors suggest 20-minutes of acupuncture per day applied for half the days of a month during a trimester as effective in reducing dysmenorrhea.48,51 The ost common needle sites for effective acupuncture in these cases, that have been proposed by the international literature, are SP6, BL54, and ST28.52,53

Aromatherapy massage has also been suggested as beneficial in minimizing pain and discomfort in patients with PD. During aromatherapy massage, essential oils are applied directly to the skin, or during a bath, or they are inhaled. Abdominal massage follows as the essential oils, mainly lavender, rose damascene, cinnamon, and clove, penetrate deep within the tissues. A recent metanalysis54 found that aromatherapy massage with the use of these essential oils is superior to placebo oils in reducing pain perception and discomfort in women with PD.55 More specifically, lavender oil was found to be better in alleviating painful symptoms in these patients compared to other mixed essential oils.27,54 Another meta-analysis by Song et al56 confirmed the positive effect of aromatherapy in reducing dysmenorrhea, but the authors underlined the high diversity and heterogeneity among studies that could potentially increase the risk of bias.

Despite the traditional approaches in use, a wide range of futuristic, novel approaches on the management of PD have been documented. Some show evidence of a possible positive effect on painful menses, while others, although widely used, are largely abandoned for this condition, such as homeopathy, due to limited scientific data.57

Hydrotherapy and heat therapy have been proposed as beneficial in pain reduction in cases of PD.58 With regards to hydrotherapy, warm baths and hip/sitz baths have been speculated as therapeutic for painful menses, while Heat patches containing iron chips have also been suggested to provide relief of PD discomfort equal to ibuprofen.59 Nevertheless, a recent systematic review and metanalysis revealed only little-to-moderate pain reduction in heat therapy.19 In other words, the role of naturopathic medicine in general might be subjective and it remains solely down to the womans initiative whether she uses such modalities. Although these practices have existed in European traditional culture since the 18th century, their contemporary use is limited.

Kinesio taping along with body awareness have demonstrated favorable outcomes with regards to minimizing pain during menses in women with PD, but the evidence is not enough to support its use widely. Similar, in that cases more studies are necessary to support or not its efficacy.10 In patients with chronic pain such as PD, studies have shown a distorted body awareness and body sensitivity, thus physiotherapy of any form (kinesio taping, electrotherapy, spinal manipulation, heat therapy, etc.) increases body awareness. The effect size of these interventions, though, is yet to be estimated in future studies.10

Another peculiar approach, in treating symptoms of PD is low-light laser level skin-adhesive therapy (LLLT), reaching a reduction of 83% compared to a placebo, as a randomized, double-blind, placebo-controlled pilot trial suggests.60 Light properties in cases of PD have also been tested with near-infrared belts used by these patients. Authors have suggested that the warmth produced by these tools improves abdominal blood supply and their efficacy can be safely compared to the use of oral analgesics.61

A number of lifestyle modifications has been found to alleviate painful symptoms accompanying PD, which should be examined under a cultural context.11 In other words, Asians and Africans were more likely to trust traditional medicine and to opt into a lifestyle that includes herbs and medicinal plants. In a recent Chinese cross-sectional study, adolescents with PD were more like to reduce physical activity and to adopt heat therapy by using warmer clothes during painful menses. Furthermore, these patients were more likely to change their diet by increasing their warm beverage and food intake. Also, these patients reported low levels of self-meditation, but were more likely to express their negative emotions due to PD to their peers in order to seek emotional support.11 On the other hand, western cultures were more likely to seek medical advice and to use pharmacological agents in order to minimize their painful symptoms and discomfort.4 Interestingly, a recent Malaysian study demonstrated that the need to reduce pharmacological agents was independent to the use of CAM modalities, but CAM users found that the absence of side-effects in CAM therapies improved their QoL62 (Figure 1).

Figure 1 Benefits of lifestyle targeted approaches on the management of PD.

Abbreviations: PD, primary dysmenorrhea; CAM, complementary and alternative medicine; QoL, quality-of-life.

Alcohol consumption and smoking is reported as a risk factor for developing PD.1,4 Unfortunately, at this time the scientific evidence does not quantify alcohol consumption, smoking, or environmental tobacco smoke for patient with PD.4 In general, although no threshold can be estimated, potentially smoking cessation and overall alcohol withdrawal are wise strategies to improve their QoL regardless of the existence of underlying PD.

Socio-economic status seems to play a crucial role in young adolescents during first years of university, when various studies report that the symptoms of PD are accompanied by an extreme severity.1 Possibly, different cultural and religious beliefs seem to exacerbate painful feelings of dysmenorrhea that are exacerbated among peers of different racial backgrounds, as it is usually the case in universities. Women of families of lower monthly income present with severe menstrual pain, a fact that might be explained by the inability to seek medical attention for their condition.1

The correlation between psychological factors and primary dysmenorrhea has been thoroughly described in the literature.63,64 The experience of recurrent menstrual pain increases the risk of mental disorders and especially stress, anxiety, and depression, but also alcohol abuse and somatic symptoms disorders.64 In addition, the comorbidity of dysmenorrhea and depression may contribute to an increased focus on symptoms and by extent on the perceived intensity of pain.63,65

The tendency to maximize negative thoughts about pain is known as pain catastrophizing and seems to be associated with the frequency and intensity of pain and emotional distress, as well as with the consequent decreased functionality. Research suggests that women with dysmenorrhea report high levels of catastrophizing pain,66 as well as increased pain intensity, lower perceived effectiveness of over-the-counter drugs, and significant lack of functionality.67 Although it remains unclear whether pain catastrophizing is a personality trait or a coping strategy, it seems to be associated with the adoption of poor coping strategies both cognitively (eg, distraction and imagery) and behaviorally (eg, reduced activity).6769

It is widely accepted that the experience of pain should be considered through an interdisciplinary approach. Support programs, and in particular those including the Cognitive Behavioral Therapy (CBT), appear to be effective in increasing knowledge about primary dysmenorrhea and reconstructing dysfunctional cognition with more rational ones, as well as increasing self-regulation skills. These interventions result in a better understanding of the meaning of pain, decrease of symptoms, and reduction of analgesic use.70,71 Well-designed studies are needed for a deeper understanding of the relationship between common mental health conditions and primary dysmenorrhea that will ensure a better clinical approach.

Since it has been well-established that body image awareness and general health perception affect the intensity and duration of pain for these women, trained specialists should promote a more holistic approach by integrating lifestyle changes into the management of primary dysmenorrhea.62,72,73 Lifestyle alterations could benefit the overall health of these women and improve their Quality-of-Life.74 Figure 2 comprises the aforementioned lifestyle focused approaches into the management of PD.

Figure 2 Integrating lifestyle focused approaches into the management of PD.

Abbreviations: BMI, body mass index; CAM, complementary and alternative medicine.

CAM modalities seem to be widely accepted and adopted by women in adolescence or of reproductive age affected with perimenstrual pain and discomfort. International literature provides controversial scientific evidence with regards to their benefits, while the majority of them hide undocumented risks.

CAM approaches are non-pharmacological and promise to offer relief and to reduce side-effects. These CAM remedies are often self-prescribed with little or no professional caregivers oversight, thus further studies need to be conducted in order to prove or disregard their efficacy in cases of PD.

All authors declare no conflicts of interest nor funding of any kind.

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34. Gao L, Jia C, Zhang H, Ma C. Wenjing decoction (herbal medicine) for the treatment of primary dysmenorrhea: a systematic review and meta-analysis. Arch Gynecol Obstet. 2017;296(4):679689. doi:10.1007/s00404-017-4485-7

35. Jesuno FW, Reis JP, Whitaker JCP. Effect of synadenium grantii and its isolated compound on dysmenorrhea behavior model in mice. Inflammopharmacology. 2019;27(3):613620. doi:10.1007/s10787-018-0501-1

36. Seo J, Lee H, Lee D, Jo H-G. Dangguijagyag-san for primary dysmenorrhea. Medicine (Baltimore). 2020;99(42):e22761. doi:10.1097/md.0000000000022761

37. Barassi G, Bellomo RG, Porreca A, Di Felice PA, Prosperi L, Saggini R. Somato-visceral effects in the treatment of dysmenorrhea: neuromuscular manual therapy and standard pharmacological treatment. J Altern Complement Med. 2018;24(3):291299. doi:10.1089/acm.2017.0182

38. Cha NH, Sok SR. Effects of auricular acupressure therapy on primary dysmenorrhea for female high school students in South Korea. J Nurs Scholarsh. 2016;48(5):508516. doi:10.1111/jnu.12238

39. Abaraogu UO, Igwe SE, Tabansi-Ochiogu CS. Effectiveness of SP6 (Sanyinjiao) acupressure for relief of primary dysmenorrhea symptoms: a systematic review with meta- and sensitivity analyses. Complement Ther Clin Pract. 2016;25:92105. doi:10.1016/j.ctcp.2016.09.003

40. Zhao MY, Zhang P, Li J, et al. Influence of de qi on the immediate analgesic effect of SP6 acupuncture in patients with primary dysmenorrhoea and cold and dampness stagnation: a multicentre randomised controlled trial. Acupunct Med. 2017;35(5):332338. doi:10.1136/acupmed-2016-011228

41. Bldt S, Pach D, Eisenhart-Rothe SV. Effectiveness of app-based self-acupressure for women with menstrual pain compared to usual care: a randomized pragmatic trial. Am J Obstet Gynecol. 2018;218(2):227.e1227.e9. doi:10.1016/j.ajog.2017.11.570

42. Zhai SJ, Ruan Y, Liu Y, et al. Time-effective analgesic effect of acupressure ankle strip pressing wrist and ankle acupuncture point on primary dysmenorrhea: study protocol clinical trial (SPIRIT compliant). Med. 2020;99:12. doi:10.1097/MD.0000000000019496

43. Abaraogu UO, Igwe SE, Tabansi-Ochiogu CS, Duru DO. A systematic review and meta-analysis of the efficacy of manipulative therapy in women with primary dysmenorrhea. Explore. 2017;13(6):386392. doi:10.1016/j.explore.2017.08.001

44. zgl S, zelpasaci E, Orhan C, Baran E, Beksa MS, Akbayrak T. Short-term effects of connective tissue manipulation in women with primary dysmenorrhea: a randomized controlled trial. Complement Ther Clin Pract. 2018;33:16. doi:10.1016/j.ctcp.2018.07.007

45. Demirtrk F, Yilar Erkek Z, Alparslan , Demirtrk F, Demir O, Inanir A. Comparison of reflexology and connective tissue manipulation in participants with primary dysmenorrhea. J Altern Complement Med. 2016;22(1):3844. doi:10.1089/acm.2015.0050

46. Ruffini N, DAlessandro G, Cardinali L, Frondaroli F, Cerritelli F. Osteopathic manipulative treatment in gynecology and obstetrics: a systematic review. Complement Ther Med. 2016;26:7278. doi:10.1016/j.ctim.2016.03.005

47. Smith CA, Armour M, Zhu X, Li X, Lu ZY, Song J. Acupuncture for dysmenorrhoea. Cochrane Database Syst Rev. 2016;2016(4). doi:10.1002/14651858.CD007854.pub3

48. Shetty GB, Shetty B, Mooventhan A. Efficacy of acupuncture in the management of primary dysmenorrhea: a randomized controlled trial. J Acupunct Meridian Stud. 2018;11(4):153158. doi:10.1016/j.jams.2018.04.001

49. French L. Dysmenorrhea. Am Fam Physician. 2005;71(2):285292.

50. Gaubeca-Gilarranz A, Fernndez-De-Las-Peas C, Medina-Torres JR, et al. Effectiveness of dry needling of rectus abdominis trigger points for the treatment of primary dysmenorrhoea: a randomised parallel-group trial. Acupunct Med. 2018;36(5):302310. doi:10.1136/acupmed-2017-011566

51. Armour M, Dahlen HG, Zhu X, Farquhar C, Smith CA. The role of treatment timing and mode of stimulation in the treatment of primary dysmenorrhea with acupuncture: an exploratory randomised controlled trial. PLoS One. 2017;12(7):120. doi:10.1371/journal.pone.0180177

52. Armour M, Smith CA. Treating primary dysmenorrhoea with acupuncture: a narrative review of the relationship between acupuncture dose and menstrual pain outcomes. Acupunct Med. 2016;34(6):416424. doi:10.1136/acupmed-2016-011110

53. Wang H, Cao Y, Jin X, et al. Effect of an acupuncture technique of penetrating through zhibian (BL54) to shuidao (ST28) with long needle for pain relief in patients with primary dysmenorrhea: a randomized controlled trial. Pain Res Manag. 2019;2019:16. doi:10.1155/2019/7978180

54. Sut N, Kahyaoglu-Sut H. Effect of aromatherapy massage on pain in primary dysmenorrhea: a meta-analysis. Complement Ther Clin Pract. 2017;27:510. doi:10.1016/j.ctcp.2017.01.001

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[Full text] Integrating life-style focused approaches into the managemen | IJWH - Dove Medical Press

Latest launched research document on Global Complementary and Alternative Medicine Market study of 114 Pages provides detailed analysis with presentable graphs, charts and tables. The Research Study presents a complete assessment of the Market and highlights future trend, growth factors & drivers, leaders opinions, facts, and primary validated market data. The research study provides estimates for Global Complementary and Alternative Medicine Forecast till 2026*.

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The in-depth information by segments of the Global Complementary and Alternative Medicine market helps monitor future profitability & to make critical decisions for growth. The information on drivers, trends and market developments focuses technologies, CAPEX cycle and the changing structure industry players of the Global Complementary and Alternative Medicine Market.

Global Complementary and Alternative Medicine Product Types In-Depth: , Botanicals, Acupuncture, Mind, Body, and Yoga & Magnetic Intervention

Professional players: Herbal Hills, Iyengar Yoga Institute, Columbia Nutritional, Nordic Naturals, Helio USA, Yoga Tree, Pure Encapsulations, Inc, Quantum Touch, The Healing Company, John Schumacher?s Unity Woods Yoga Center, Herb Pharm & Deepure Plus

Global Complementary and Alternative Medicine Major Applications/End users: E-Sales & Direct Sales

**The market is valued based on weighted average selling price (WASP) and includes all applicable taxes on manufacturers. All currency conversions used in the creation of this report have been calculated using constant annual average 2020 currency rates.

The Global Complementary and Alternative Medicine is estimated at US$ XX million in 2020 and will reach US$ YY million by the end of 2026, growing at compound annual growth rate of ZZ% during 2021-2026.

Geographical Analysis: Regional and country level analysis integrating the demand and supply forces that are influencing the growth of the market, currently covering North America (Covered in Chapter 6 and 13), United States, Canada, Mexico, Europe (Covered in Chapter 7 and 13), Germany, UK, France, Italy, Spain, Russia, Others, Asia-Pacific (Covered in Chapter 8 and 13), China, Japan, South Korea, Australia, India, Southeast Asia, Others, Middle East and Africa (Covered in Chapter 9 and 13), Saudi Arabia, UAE, Egypt, Nigeria, South Africa, Others, South America (Covered in Chapter 10 and 13), Brazil, Argentina, Columbia, Chile & Others

** For global or regional version of report, list of countries by region are listed below can be provided as part of customization at minimum cost.

North America (United States, Canada & Mexico)Asia-Pacific (Japan, China, India, Southeast Asian Countries & Australia etc)Europe (Germany, UK, France, Italy, Spain, Russia, Netherlands & Belgium etc)Central & South America (Brazil, Argentina, LATAM etc)Middle East & Africa (United Arab Emirates, Qatar, Saudi Arabia, Israel & South Africa etc)

For detailed insights on Global Complementary and Alternative Medicine Market Size, competitive landscape is provided i.e. Revenue Share Analysis (Million USD) by Players (2018-2020), Revenue Market Share (%) by Players (2018-2020) and further a qualitative analysis is made towards market concentration rate, product differentiation, new entrants are also considered in heat map concentration.

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In this study, the years taken into consideration to estimate the market size of Global Complementary and Alternative Medicine are : History Year: 2015-2020; Base Year: 2020; Forecast Year 2021 to 2026

Key Target Stakeholders Covered in Study:==> Complementary and Alternative Medicine Manufacturers==> Global Complementary and Alternative Medicine Distributors/Traders/Wholesalers==> Complementary and Alternative Medicine Component / Raw Material Producers==> Downstream Vendors

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About Author:HTF Market Report is a wholly owned brand of HTF market Intelligence Consulting Private Limited. HTF Market Report global research and market intelligence consulting organization is uniquely positioned to not only identify growth opportunities but to also empower and inspire you to create visionary growth strategies for futures, enabled by our extraordinary depth and breadth of thought leadership, research, tools, events and experience that assist you for making goals into a reality. Our understanding of the interplay between industry convergence, Mega Trends, technologies and market trends provides our clients with new business models and expansion opportunities. We are focused on identifying the Accurate Forecast in every industry we cover so our clients can reap the benefits of being early market entrants and can accomplish their Goals & Objectives.

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Complementary and Alternative Medicine Market to Witness Huge Growth from 2021 to 2027 Cabell Standard - Cabell Standard

BURBANK, Calif., March 16, 2021 (GLOBE NEWSWIRE) -- via NewMediaWire -- Medolife Rx, Inc. ("Medolife"),a global integrated bioceutical company with R&D, manufacturing and consumer product distribution, which is a majority owned subsidiary of Quanta, Inc. (OTC PINK: QNTA),announced today results from an independent efficacy test conducted on the Companys polarization technology where the subject compound showed an increased efficacy of 497 percent when compared to its non-polarized counterpart, validating the polarization technology that is being used in most of Medolifes clinical programs and consumer products.

The aim of the study was to compare the efficacy of polarized and non-polarized Mitragyna speciosa, more commonly known as Kratom. Kratom is a natural ingredient that has been used in herbal medicine since at least the 19th century and more recently has seen an increase in interest as a potential alternative medical treatment to control withdrawal symptoms and cravings caused by addiction to opioids or to other addictive substances such as alcohol. The study measured the Adenosine triphosphate (ATP) production levels in primary human fibroblast cells and that data was used to validate the effectiveness of polarization in cellular functions. Fibroblasts were plated in 96 well plates at 10,000 cells per well and were treated for 24 hours, allowing research as to the percentage change between polarized and non-polarized versions of Kratom.

The results showed that polarization of Kratom demonstrates sufficient polarizability, which is the ability of compounds to absorb photon emission through electromagnetic resonance. The ATP production in the primary human fibroblast cells of the Polarized Kratom sample is 497 percent higher than the Non-Polarized Kratom sample.

The study is important to the Companys overall pharmaceutical and nutraceutical product research and development programs as most of the Companys products utilize the polarization technology, which was designed to increase the potency of single molecules and complex compounds. This study further validates the technology and positions the Company for further research to increase the effectiveness of various APIs, decreasing side effects of harsh compounds as well as the raw material input of medicines and nutraceutical products.

The proprietary polarization technology is the cornerstone of our medical and consumer product development programs, including our Escozine clinical program which is currently in review for product registration as a treatment for COVID-19 in the Dominican Republic, and this study further validates our technology, said Medolife CEO Dr. Arthur Mikaelian. While many pharmaceutical companies are working with new and novel compounds, our company is unique in that we could apply this technology to almost any API, currently in use or in the clinic, to increase the efficacy of those compounds for their intended purposes, a true differentiator in our space. While we may not work with Kratom in the near-term, we plan to further validate our technology with various compounds and eventually bring new clinical programs to our pipeline using the technology, that are in high-impact patient focus areas. We are pursuing clinical programs in the United States as well as in other countries around the world.

Medolifes lead clinical development programs include Escozine, a proprietary formulation consisting of small molecule peptides derived from Rhopalurus princeps scorpions, which is amplified by the Companys polarization technology and is being researched as a treatment of various indications, including COVID-19 and cancer. The Companyrecently announced results from a toxicity studyon the drug candidate that showed that at maximum dose levels the product is non-toxic and safe. The Company is seeking product registration for the treatment of COVID-19 in the Dominican Republic and has filed study data in pre-IND format with the US FDA.

About MedolifeRx

Medolife Rx, Inc. is a global biotechnology company with operations in clinical research, manufacturing, and consumer products. MedolifeRx was created through the merger of Medolife, a private company founded by Dr. Arthur Mikaelia who pioneered the unlaying polarization technology that makes the Companys portfolio of pharmaceutical and nutraceutical products so effective, and Quanta, Inc., a direct-to-consumer wellness product portfolio company. The Companys lead clinical development programs include Escozine, a proprietary formulation consisting of small molecule peptides derived from Rhopalurus princeps scorpions which is amplified by the Companys polarization technology and is being researched as a treatment of various indications, including COVID-19 and cancer. The Company has completed preclinical safety and efficacy research on Escozine and is pursuing product registration and drug approval in various countries, including the United States and throughout Latin America.

Through its subsidiary QuantRx, Medolife manufactures and distributes consumer wellness and nutraceutical products in high-impact consumer areas such as pain relief, beauty, and general wellness. QuantRx products are designed using Dr. Mikaelias polarization technology which applies advances in quantum biology to increase the potency of active ingredients. Currently, QuantRx supports product formulations in pain management, anti-inflammation, skincare, agriculture, nutritional supplements, and plant-based consumables. Ultimately, Quanta's mission is to deliver better, more effective ingredients to elevate product efficacy, reduce waste, and facilitate healthier, more sustainable consumption.

Beyond its own clinical and consumer applications, the polarization technology used by Medolife and its subsidiaries has many potential applications. From potentiating bio-ingredients, to producing more-effective carbon-trapping plants, to transformative anti-aging solutions, Medolife has the opportunity to upend how commercial and pharmaceutical products are made and increase their benefits, while decreasing their chemical concentration.

Forward-Looking Statements

Safe Harbor Statement under the U.S. Private Securities Litigation Reform Act of 1995: This release contains statements that are forward-looking in nature which express the beliefs and expectations of management including statements regarding the Company's expected results of operations or liquidity; statements concerning projections, predictions, expectations, estimates or forecasts as to our business, financial and operational results and future economic performance; and statements of management's goals and objectives and other similar expressions concerning matters that are not historical facts. In some cases, you can identify forward-looking statements by terminology such as "anticipate," "estimate," "plan," "project," "continuing," "ongoing," "expect," "we believe," "we intend," "may," "will," "should," "could," and similar expressions. Such statements are based on current plans, estimates and expectations and involve a number of known and unknown risks, uncertainties and other factors that could cause the Company's future results, performance or achievements to differ significantly from the results, performance or achievements expressed or implied by such forward-looking statements. These factors and additional information are discussed in the Company's filings with the Securities and Exchange Commission and statements in this release should be evaluated in light of these important factors. Although we believe that these statements are based upon reasonable assumptions, we cannot guarantee future results. Forward-looking statements speak only as of the date on which they are made, and the Company undertakes no obligation to update publicly or revise any forward-looking statement, whether as a result of new information, future developments or otherwise.

Contacts:Phil Sandshttps://ir.quantrx.com/818-659-8052

Kyle Portermedolife@cmwmedia.com858-264-6600

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MedolifeRx Announces Results From Efficacy Test on Polarization Technology Showing 497 Percent Increase in Efficacy of API When Polarized -...

HOUSTON, Texas, March 17, 2021 (GLOBE NEWSWIRE) -- via NewMediaWire -- China Infrastructure Construction Corp.(OTC: CHNC)https://www.chnc-hdh.com/:With all hands on deck, and an axiomatically relentless effort to endure and continue to withstand the test of time, CHNC intends to continue to improve its overall performance. And, in addition to its short and long-term promising projects, as well as the need and desire to provide our shareholders andpartnersa great return on their investment; suitably, the board of directors at CHNC by virtue of a cash transaction sealed a buyback of4billion shares, with no dilution effect to shareholders.All the same, shareholders can restassuredwith shrewd knowledge that the ownership of the company that each one hasintheirpossession has not been reducedor diluted. The four billion shares acquired have nowbecome part of the treasury of the company, says Elizabeth Hernandez, COO of CHNC. This move resembles the re-acquisition by a company of its own shares known as a Buyback. Some of you may remember that such transactions used to be deemed as market manipulation, and thats why it was illegal until 1982. After that, buybacks became a frequent practice, and are better used because of different reasons such as ownership consolidation, undervaluation, financial statements, even for compensation purposes (for instance an Employee Stock Option Plan). Among the companies that have performed a buyback we find Apple, Microsoft, Oracle, Berkshire Hathaway, and others. Without a doubt, buybacks have slowly overtaken dividends as a preferred way to increase shareholder value.

On a different note, we continue to nurture and water the collegiate development of our educational training programs aimed at a different public than just consumers/experts of cannabis, whereby, we are now educating doctors, businessmen, legislators, and politicians. Before the present, medical cannabis as a stable business was just a multicolor hallucination, or a political suicide for public office legislators, but with patience and education, cannabis as medication has slowly gained weight and relevance. As an example with accredited educational standards, Colombia, a country with a well-known bloodstained historicalwar on drugs, swiftly took a great step of legalizing cannabis for medical purposes in 2017, gradually changing to be one of the most profitable educational destinations of our franchises and academic venues. Therefore, we are pleased to inform of the novel and renewed alliances made with educational entities such as UTADEO (Universidad Jorge Tadeo Lozano) located in Bgota-Colombia, which for 3 years has collaborated with our firm and featured our educational 12 and 14 weeks Diplomado Curricula, making us pioneers of our Accredited University Diploma Courses, to certified cannabis pedagogical programs in Latin America. It should be noted that these curriculums have had an international reach, with students, health professionals, agronomists, chemists, and patients from countries such as Brazil, Spain, France, Uruguay, Mexico, Peru, USA, and Chile traveling from around the world to Colombia to attend our Diplomados.

Close to the wind, once more we proudly announce our freshest and right out of the oven alliance with the UTB (Universidad Tecnolgica de Bolvar), located in Cartagena Colombia, where we will continue to bet and plant seeds for awareness of cannabis as medicine, research and education.Whats more, we intend to expand our participation to include international exchange programs,as wellasone week summer symposiums with Cannabis leaders-executives from around the world.

If one has ever readOne Hundred Years of Solitude, you will remember that the magical realism of this book, awarded with a Nobel Literature Prize, was inspired by the history of the Caribbean. Hence, given the circumstances, CHNC intends to write a second live oracle edition of the celebrated manuscript, by helpingwrite a page in the history of cannabis in Colombia that will not be tainted or stained with blood, says Anne Graham, In-house Legal Counsel for CHNC. Instead, a scientific story that describes the palliative effects of the flower as medication for the medicinal use of those that have been left behind by traditional medication, in other words out with the opioids in with the cannabinoids, says Dr. Julian Gonzalez, Advisory Board Member of CHNC.Whereby, we can create a new paradigm shift and an introduction to medical therapies, employment and financial opportunities to the magical land ofMacondo.And so, our new academic alliance will commence its history in the cities that inspired the magicalstory; as well Students from all over the world who participate in our diplomas will have the opportunity to visit Cannabis cultivation facilities in Santa Marta, Colombia, (where some of the most recognized cannabis strains in the world originated,ColombianGold), they will also be able to participate in exchanges with already operating cannabis enterprises within the region.

For sure, a lot of progress has taken place in the Latin land, but cannabis goes beyond borders via its transmutation reconstruction and by slowly liberating itself. Be that as it may, the United States is not staying behind in this process, with a 35% increase over 2019, legal medical and adult-use cannabis proceeds that reached the amount of $12.9 billion, and according to statistical outlooks, the sales will hit $20.4 billion by 2022.What is more,with continuedlegalization taking place in parts of the USA, Mexico, and other countries;plus,if we consider the unfortunately still illegal marijuana sales during the last years, we apparently are in front ofindustry revenues inthe vastness of $48.5 billion by 2022, with a quantitative outlook with a pledge promise of a boundless place to be, for a research and educational firm.

Therefore, CHNC reiterates its commitment to the medical cannabis industry, to patients affected by a variety of conditions who seek a natural and efficient alternative to healthcare and to professionals who wish to learn or enhance their knowledge; similarly, to those whose interest was awakened and seek answers to their uneducated present condition.Precisely, this is why we are as pleased as a dog with two tails about the fact that our project "Phytotherapy with cannabinoids for the reduction of symptoms of COVID-19" is presently being sent to executives from different corporations and countries. Our firm is finally beginning to have a life of its own! says Henry Levinski, Treasurer of CHNC. The communiqu that is being sent to some of the most recognized companies, people or funds in the world, can be read at this link https://www.chnc-hdh.com/covid-19.Likewise, for all those interested in knowing who we are sending the Phytotherapy presentation to, can see the list at the following linkhttps://www.chnc-hdh.com/covid-19-contact.

More to the point, please know that our digital publications Cannamed and Cannalaw will soon be enjoying a new sister publication that has been baptized by the name Cannatrade, focusing solely on the up-to-the-minute business aspects of the industry. The cannabis trade is constantly changing; we are surrounded by new businesses, legal challenges and ground-breaking discoveries on a daily basis without any precedent. We understand how overwhelming it can be to keep up with a market that is evolving more and more by the minute and is now an international commerce. Therefore, Cannatrade is attentive to the exciting changes that are stirring the industry such as how is the cannabis stock market, what companies are growing and are attractive to invest, what international businesses are being conducted, what are the alliances that have materialized between countries. With Cannatrade we wish to give the user updated financial information, knowledge on what is out there and how they can by education become part of the speed of light global evolution. For a limited time only, if you would like to apply for an early subscription visit the following linkhttps://www.chnc-hdh.com/canna-trade.

With our new magazine we wish to continue to grow as our currentdigital publicationsthat havepresently reached distribution in an astonishing 70 countries (Andorra, Algeria, Arab Emirates, Argentina, Australia, Austria, Bahrain, Bolivia, Bonaire, Brazil, Cabo Verde, Canada, Chile, Colombia, Costa Rica, Curacao, Czech Republic, Denmark, Dominican Republic, Ecuador, Egypt, El Salvador, Estonia, France, Germany, Guinea, Equatorial Guinea, Greece, Guatemala, Honduras, Iraq, Ireland, Israel, Italy, Ivory Coast, Jamaica, Jordan, Kuwait, Lesotho, Lebanon, Libya, Mexico, Morocco, Malta, Mauritania, Nicaragua, Norway, New Zealand, Palestinian Territories, Panama, Paraguay, Peru, Portugal, Puerto Rico, Qatar, Saudi Arabia, Spain, Syria, Sudan, Sweden, Switzerland, Tunisia, United Kingdom (UK), United States, Uruguay, Venezuela, Yemen and Zambia)... and what is yet to come.

Conclusively, CHNC would like to thank all of our shareholders for their persistent support, inspiration and constant communication that at times for legal reasons we cannot always respond. But be certain that we are here with every intention to victoriously make it to the fourth quarter. Equally important, my gratitude to our front-line partners that tirelessly provide us with their indomitable exertion and support so that we can day by day taste the fruits of our healthy disregard for the impossible. And call to mind that "Every day is an opportunity to innovate and work for global health, from the field of alternative medicine," says Dr. Jose Torres, Director and International Medical Director of CHNC.

Safe Harbor Statement

The information posted in this release may contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. You can identify these statements by use of the words "may," "will," "should," "plans," "explores," "expects," "anticipates," "continue," "estimate," "projects," "intends," and similar phrases. Forward-looking statements involve risks and uncertainties that could cause actual results to differ from those projected or anticipated. These risks and uncertainties include, but are not limited to, general economic and business conditions, effects of geopolitical conditions, competition, changes in technology and methods of marketing, and various other factors beyond the company's control.

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CHNC: Intensity, Determination and a Magical Unwavering Direction Transports CHNC to Become the Macondo of Medical Cannabis Research - GlobeNewswire

When it comes to wellness, the gut is the cornerstone of the overall health and wellbeing of people. However, according to Dr. Saya Pareeth and Dr. Hafeel Ambalath, the founders of The Healers Clinic in Dubai, its a topic that is particularly important, yet is ignored.

With both having extensive experience in holistic care and Ayurvedic treatments, the clinics clear mantra is about healing from the core. In our 20 years together, we have devised innovative protocols in traditional and integrative medicine and have advised people in this arena, the co-founders explain.

In-keeping with the clinics holistic health methods, ensuring the root cause of health issues are dealt with rather than just the symptoms, gut health directly reflects this. Gut health has always been the starting point for age-old health traditions and our practice too, has always been deeply rooted in this concept, they explain.

Dr. Pareeth and Dr. Ambalath sat down withEmirates Womanto discuss their five-year journey with The Healers Clinic, what they focus on and the importance of shining a light on gut health.

One of the challenges was to first understand why we are born on this planet and then are given this huge opportunity to be able to serve people. As a medical professional, often we are overawed with the burden and responsibility placed on us. One of the primary reasons to start The Healers Clinic was to look beyond an okay life and spread the knowledge of traditional medicine, to lead a holistic life. On another level, the rather small number of facilities offering holistic and integrative care was one of the driving forces behind The Healers Clinic.

Our primary aim was to fill the gap between individuals or families and an integrative or holistic family-physician. We wanted to make integrative and holistic care, easily accessible to all who needed it. We also aimed to build awareness in individuals as well as families, on preventive care, rejuvenation, and maintenance of good health, by way of our unique methodologies and practices. And of course, we wanted to see Dubai as a hub of health tourism, where the world got to experience what traditional and alternative medicine can do.

Holistic refers to a complete form of healthcare that does not reject conventional medicine. Instead, it considers a comprehensive and individualized picture of health while using safe, effective and appropriate options for prevention or healing. It involves looking at an individual as a whole, to determine the underlying balances that may affect his or her health.

Speaking of ourselves while we function on the ancient philosophy of preventive health care systems, and practice traditional healing we adapt them and implement them through modern and scientific platforms. We do not restrict ourselves to any one form or method of medical treatment. Incorporating approaches from across the world, we choose a course of treatment best suited to an individuals needs and tailored to individual lifestyles. This briefly describes the holistic approach we have successfully taken, to health and wellness. This also is the beauty of The Healers Clinic as we focus on the overall wellbeing of individuals and on strengthening their core health pillars than indulge in superficial quick fixes.

The bodys gastrointestinal tract and its functions are the cornerstones of our well-being. Numerous studies have shown the connection between our gut health and our immune system, mental health, skin health, endocrine and early points in pathogenesis. Gut health has always been the starting point for age-old health traditions and our practice too has always been deeply rooted in this concept.

It is a large part of discussions doing rounds in health and wellness space because, in simple language, you are talking about a stronger immune system, clearer skin, weight control, hormones, improved state of mind, less bloating, better quality of sleep and improved digestion.

Our gastrointestinal tract is a universe and an ecosystem within us. It is a contained world of complex chemistry and microbes controlled by indefinable energy of intricate movements and messenger systems. The digestive membrane, which makes the walls of this passage and storage space, with little processing units of its own, determines the nature of chemical relations with the outside world of tissues and cells.

In other words, the digestive system decides just what and how much becomes a part of our energy and tissues! A healthy gut reflects not just on your skin but also on your immune system, mood, sleep, digestion, hormonal balance and weight it is the foundation of overall wellbeing.

We would suggest facilitating the body to do what it actually wants to do. We would also suggest reducing pressure on the gut by simplifying the way one treats oneself by eating well and in a healthy manner, getting sufficient sleep, exercising regularly and more. Always listen to the body. Watch what you eat. Watch your day, watch your bowels and your energy levels. Most of the learning happens here. As an integrative and holistic care facility, The Healers Clinic uses age-old, traditional and time-tested eastern ways of understanding the gut with tools and investigations made available by modern western science, such us non-linear health screening. A treatment plan is then designed for an individual.

Vegetables and seasonal fruits are the best. Go slow on grain though. Fish and occasionally, chicken or meat could be a part of your meal plan, but you do not have to consume meat every day. Eating a range of diverse foods that can give rise to new types of bacteria can be beneficial to gut health. Include whole fruits and vegetables that are fibrous and fermented foods like yoghurt, kimchi and sauerkraut.

No single form of treatment or medication can replace proper and healthy eating or lifestyle habits. The Healers Clinic, which is a centre of excellence in integrative and holistic care, encourages people to start on a journey of detox and rejuvenation, wherein we introduce or reinstate healthy gut habits. We take our learning from world cultures and the ancient Ayurveda to introduce cleansing and strengthening gut-health practices. The experience we have gained through our work in the local community, embracing different health cultures it gives us the confidence to say that prevention of disorders and sustenance of good health can be made possible by respecting traditional wisdom along with the modern and scientific understanding. This is what we have made our Vision and our vision is what made us start The Healers Clinic.

We believe that wellness refers to more than just the absence of an ailment. To be precise, it refers to a state of health which is a result of an actively pursued, daily goal. It involves change and therefore growth and is a state of mental, physical and social fitness and stability. We aspire to help people achieve this state! Watch what you eat, when you eat, and how you eat. Avoid overeating and having meals at improper timings. Watch your bowels. The body tells you a lot you need to know. Listen to it.

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What you need to know about gut health and how it affects your body Emirates Woman - Emirates Woman