Category Archives: Alternative Medicine

Phillip D. Wilson, D.D.S., assistant clinical professor in the University of New England College of Dental Medicine (CDM), is one in a team of authors of a clinical research report on oral appliance therapy (OAT) as an alternative treatment for obstructive sleep apnea (OSA), which was recently published in the Journal of Dental Research.

The report, Randomized Trial of 2 Self-Titrated Oral Appliances for Airway Management, compared two widely used oral appliance (OAs) designs and tested whether they differed in reducing the respiratory event index (REI) a figure used to indicate the severity of OSA.

The randomized crossover study examined the differences in reducing REI between two oral appliances: the TAP1 and SomnoDent Flex. Due to design differences, the TAP1 device tends to restrict mouth opening during sleep, while the SomnoDent Flex allows for complete mouth opening. The goal of the research was to determine if these design variances had differing effects and if OAT was even effective in treating OSA.

To complete the study, participants used one dentist-fitted OA nightly for four weeks followed by a one-week washout period, during which participants were instructed to use their CPAP machines instead. This washout period was followed by a second four-week trial during which participants used the alternate OA.

Individuals received training on how to titrate each appliance and were instructed to advance their mandibles based on each manufacturers guidelines if they observed any snoring, OSA events, or persistent daytime sleepiness. To measure REI, home sleep recordings were collected using the NOX T3 recorder, and oxygen saturation was measured with a finger probe pulse oximeter.

After nine weeks, the researchers found that both devices demonstrated equivalent REI attenuation regardless of jaw-opening limitations, and both designs significantly reduced the REI in adults with moderate and severe OSA. These findings were somewhat surprising because the current understanding is that OAT was only effective for those suffering from mild OSA, Wilson said.

When self-titrated over a short period of four weeks, the results suggest that both designs improve upper airway function and stability, reduce its collapsibility, and increase oropharyngeal space, the team wrote. Collectively, our data suggest self-titrated OAs can be routinely offered as a treatment option for OSA patients, and clinicians can expect about a 50% response rate and to bring the REI down to about eight to 16 events per hour after eight weeks among patients, including those with severe OSA.

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Professor's study on alternative treatments for sleep apnea published in Journal of Dental Research - University of New England

A recent review took a look at the promise of measuring circulating tumor DNA (ctDNA) with digital-droplet PCR (ddPCR) in pancreatic ductal adenocarcinoma (PDAC) as the landscape of this cancer continues to shift toward personalized, precision treatment.

Circulating tumor DNA (ctDNA) has emerged as a promising biomarker in several cancers and a viable alternative to traditional blood-based protein biomarkers, including in pancreatic ductal adenocarcinoma (PDAC), one of the deadliest forms of cancer.

A recent review took a look at the promise of measuring the novel biomarker with digital-droplet PCR (ddPCR) in PDAC as the cancer landscape continues to push toward personalized, precision treatment. In this setting, ctDNA allows for a unique approach to exploring genetic mutations that may be translated into the clinical setting, explained the authors of the review.

Liquid biopsy is of great importance in PDAC as adequate tumor tissue is scarce. The trouble of obtaining enough tumor sample to carry out molecular studies in PDAC makes it difficult to advance the field of personalized therapy in this tumor type, wrote the authors. For this reason, the possibility of performing genetic studies in peripheral blood takes on special relevance in PDAC and would probably stimulate the advancement in precision medicine in these patients.

The ddPCR approach hinges on nanoliter-sized water-in-oil emulsion droplet technology and allows for accurate quantification of a small amount of circulating nucleic acids in plasma. The sensitive, accurate approach has suggested the possibility of alternative, unestablished biomarkers in PDAC that have traditionally eluded alternative, more traditional methods.

In one study, ddPCR identified plasma KRAS mutant ctDNA in 8 of 31 patients (26%) that were at various stages of disease. The researchers of the study also found that KRAS mutant detection has significant associations with inferior overall survival (OS). Similar results were shown in several other studies that showed an approximately 30% ctDNA KRAS detection rate with ddPCR and determined associations between KRAS mutations and OS.

NGS approaches have the potential to detect a broad range of molecular targets. Therefore, most studies have focused on the presence of ctDNA mutations in a comprehensive set of genes to highlight tumor heterogeneity and demonstrate clonal evolution over the course of disease progression, wrote the researchers. In these types of studies, ddPCR technology has been performed in order to validate NGS results and to follow-up the disease. Thus, [next-generation sequencing] has been combined with ddPCR for liquid biopsy analysis.

The researchers highlighted one study of 51 patients that used somatic mutations in ctDNA to identify patients who would likely relapse following surgical intervention, tumor tissue whole-exome sequencing revealed different somatic mutations that would likely be detected in ctDNA. Using ddPCR, they focused on alterations in KRAS, BRAF, and PIK3CA both prior to and after tumor resection in localized PDAC. There were alterations found in 43% of patients, and analyses revealed that patients with ctDNA in their plasma after resection were at a higher risk of relapse.

Reference

Huerta M, Rosell S, Sabater L, et al. Circulating tumor DNA detection by digital-droplet PCR in pancreatic ductal adenocarcinoma: a systematic review. Cancers. 2021:13(5):994. doi: 10.3390/cancers13050994

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Measuring ctDNA With ddPCR May Help Drive Precision Medicine in Pancreatic Cancer - AJMC.com Managed Markets Network

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Introduction

Pain is an unpleasant sensory and emotional perception associated with actual or underlying tissue pathology. It has become an important healthcare and social problem for its high incidence, great influence on quality of life and high medical costs. It was estimated that more than 20% of the population visit the clinic with pain as the main complaint every year.1,2 Studies have shown that patients with pain are at risk for illness absenteeism and poor health-related quality of life. An assessment of health care spending in the United States estimates that the annual cost of treating pain is $ 635 billion.3

Due to the complex cause and recurrent symptom, the targets of treatment options for pain are poor. As the most commonly used treatment, medicine (eg, muscle relaxants and non-steroidal anti-inflammatory drugs) can quickly alleviate acute pain, but its side effects can not be ignored.4 So seeking for effective complementary and alternative therapies (C&AT) attracts both patients and practitioners. Acupuncture, as a component of traditional Chinese medicine, has been extensively used in the treatment of pain for more than 3000 years, and hundreds of clinical and experimental studies were published during the last decade, it is a need for reviewing the study status to provide the reference for future studies. This study aims to scientifically collect the literature of acupuncture for pain from 2010 to 2020, including clinical research and animal experiments, review the research status, analyze the research trends and hot spots, and explore the potential problems in this field, so as to promote future research and clinical application.

In this study, we adopted the Web of Science core collection database as our database because it provided references that have been compiled according to the requirements of CiteSpace software for formatting references used for co-citation analysis. Web of Science also has a wide range of references, which may have higher citation rates. Therefore, this database was appropriate for our study.

We selected a core collection of databases from the Web of Science for studies on acupuncture for pain. The data search strategy included the topic acupuncture and pain, with the publication period of the literature ranging from 2010 to 2020. We excluded articles that could not be obtained as full texts and repeated publications. There were no restrictions on language, type of document and type of research including interventions, mechanisms, diagnosis, and other related studies.

We used CiteSpace 5.6 and Excel 2019 to analyze data for articles used in the study. Our analysis included the following: (1) descriptive statistical analysis, descriptive analysis of the annual publication volume, journals, countries, institutions, authors, references, and keywords; (2) co-occurrence analysis, a co-occurrence map for countries, institutions, author cooperation networks, keywords and burst keywords was drawn. A cooperative analysis of institutions and authors was based on all authors, and the section of cited authors was extracted by the first author for analysis. Keywords were analyzed by extracting keywords listed in selected articles. We directly analyzed the original keywords in the data set and supplementary keywords in the database; (3) cluster analysis which involved clustering co-citations of articles to investigate changes in research topics over time.

Research quality was controlled through the following methods: (1) formulation of strict search terms to ensure recall rate, (2) research results for the final knowledge map were confirmed by experts in relevant fields to verify guidance of research conclusions for clinical practice.

A total of 4227 articles were used in this study. The number of articles published each year is shown in Figure 1. The number of articles published increased from 292 in 2010 to 442 in 2020, indicating that the number of publications is increasing but fluctuating.

Figure 1 The number of acupuncture treatment for pain publications from 2010 to 2020.

The number of journals that published 4227 articles on acupuncture treatment for pain was 850. The ten most active journals are listed in Table 1 and publishers of these journals were mostly located in the United States or England. Most of the articles were published in the Journal of Evidence-Based Complementary and Alternative Medicine (Evid Based Complement Alternat Med), followed by the Journal of Acupuncture in Medicine (Acupunct Med) and the Journal of Alternative and Complementary Medicine (J Altern Complem Med). Furthermore, we found that the Cochrane Database of Systematic Reviews (CDSR) with the highest IF is a leading journal and database for systematic reviews in health care, with an IF of 7.89.

Table 1 The Top 10 Journals with the Highest Frequency of Acupuncture Treatment for Pain

The analysis of co-citation of journals indicates a distribution of significant knowledge sources in a particular field. Results of our statistical analysis revealed that the total number of journals that published articles on acupuncture treatment for pain was 963. The most frequently cited journals were Pain, followed by the Journal of Alternative and Complementary Medicine (J Altern Complem Med), Evid-based Compl Alt (Tables 2 and 3). In terms of centrality, the top 5 journals were: Pain, Journal of Neuroscience (J Neurosci), Journal of Applied Physiology (J Appl Physiol), Journal of Advanced Nursing (J Adv Nurs) and Brain Research.

Table 2 The Top 5 Cited Journals with the Highest Frequency of Acupuncture Treatment for Pain

Table 3 Top 5 Cited Journals with the Highest Centrality Associated with Acupuncture Treatment for Pain

We used CiteSpace to generate a map of countries with 85 nodes and 369 links. The size of nodes in the cooperation graph indicated the number of articles published by a country, and the links between nodes represented the strength and time of the cooperative relationship (Table 4 and Figure 2). A total of 4227 articles on acupuncture treatment for pain have been published in 85 countries. The top 5 countries have published 3457 articles, constituting 81.78% of the total publications. The China accounted for 29.62% (1252/4227) of the total publications, followed by the United States (27.04%), South Korea (10.39%), England (8.75%) and Germany (5.98%). The top five countries with centrality were the United States (0.46), England (0.27), China (0.16), Italy (0.12) and Germany (0.09).

Table 4 Top 5 Countries Related to Acupuncture Treatment for Pain

Figure 2 A country cooperation map related to acupuncture treatment for pain research from 2010 to 2020.

We used CiteSpace to generate agency maps with 457 nodes and 1950 links. Agency maps indicated that the 4227 articles were submitted by 457 scientific research institutions. The top 5 institutions based on the number of publications included: Kyung Hee University (5.39%), Beijing University Chinese Medicine (3.24%), Chinese Academy of Chinese Medical Sciences (3.10%), Korea Institute of Oriental Medicine (2.82%) and China Medical University (2.77%) (Table 5 and Figure 3). The top 5 institutions in centrality were Kyung Hee University, University of Maryland, China Medical University, Harvard university and Beijing University Chinese Medicine.

Table 5 Top 5 Institutions Related to Acupuncture Treatment for Pain

Figure 3 An institution cooperation map related to acupuncture treatment for pain research from 2010 to 2020.

CiteSpace software was used to generate a co-authors map showing 565 nodes and 1675 links. The size of nodes in the cooperation graph represented the number of articles published by an author, and the link between them reflected the strength of their cooperative relationship (Table 6 and Figure 4). A total of 4227 articles were published by 565 authors. Lee MS was the most active author in this research field with 51 articles, followed by Liang FR (49 articles) and MacPherson H (48 articles).

Table 6 Top 5 Active Authors Related to Acupuncture Treatment for Pain

Figure 4 A coauthor map related to acupuncture treatment for pain research from 2010 to 2020.

CiteSpace was used to generate a co-authors map displaying 853 nodes and 6914 links. The size of nodes represented the number of author citations and the link between them indicated the strength of co-citation (Table 7). The top 5 most cited authors were MacPherson H (577), Han JS (534), Vickers AJ (500), Linde K (420), and Ernst E (383). The top 5 authors in centrality were Kong J, Itoh K, Cherkin DC, Lund Irene, and White P.

Table 7 Top 5 Cited Authors Related to Acupuncture Treatment for Pain

Co-citation implies that two articles appear together in the reference list of a third cited article thus the two articles form a co-citation relationship. Co-citation suggests that the cited literature and corresponding research are related in content, and the literature usually contains high-quality content which has significant influence in a particular field of research. Moreover, the relationship between literature co-citation is likely to change with time. Study of the network for literature co-citation can facilitate investigation of the developments and evolution in a specific discipline. A total of 99,873 reference articles were extracted from the 4227 articles to analyze cited references. We considered 2010 to 2020 as our time span and a time slice of 1. Fifty most frequently cited or items which appeared were selected from each time slice to form a network diagram of cited references comprising 925 nodes and 5029 links. An analysis in terms of cocitation counts and centrality (Tables 8 and 9) revealed that the data on this topic over the past decade are generally in the form of 1) randomized trials, 2) meta-analysis, 3) research on the mechanism of acupuncture analgesia, and 4) placebo effect of acupuncture.513

Table 8 The Top 5 Cited References for the Highest Frequency of Acupuncture Treatment for Pain

Table 9 The Top 5 Cited References for the Highest Centrality of Acupuncture Treatment for Pain

We applied a logarithmic likelihood ratio (LLR) algorithm to assess nominal terms extracted from the keyword list of articles to naming of clusters to explore research models and emerging trends in knowledge systems, and to obtain key information from cited references. Seventeen clusters were generated with a modularity value of 0.6822, indicating that clustering results were highly reliable (Figure 5). Silhouette was 0.3321, implying that the resulting network community structure was significant. Results proved that our cluster was reasonable. We have listed the first 8 clusters with the largest scale, and the number of articles represented the importance of the clustering domain obtained. The largest group was placebo effect, which consisted of 109 reference articles. Cluster # 4 knee osteoarthritis was drawn using cold colors to indicate that it was a new research direction that had recently emerged.

Figure 5 Reference cocitation map related to acupuncture treatment for pain research from 2010 to 2020.

Research frontiers can be identified by analyzing keywords. A keyword co-occurrence network containing 624 nodes and 6508 links was generated. Table 10 and Figure 6 represent a network of co-occurring keywords with high frequencies; the larger the character, the higher the frequency of the keyword. The most widely used keywords related to acupuncture treatment for pain over the last few years were acupuncture, pain and electroacupuncture.

Table 10 Top 10 Keywords Related to Acupuncture Treatment for Pain

Figure 6 Keyword co-occurrence map related to acupuncture treatment for pain research from 2010 to 2020.

Burst keywords were automatically generated by the software based on the keywords in the list, used to record a keyword that changes greatly within a short period of time. It is considered to be another crucial indicator of research hotspots or future trends. The top 20 keywords that were frequently cited over time are presented in Figure 7.

Figure 7 Top 20 keywords with the strongest citation bursts.

To the best of our knowledge, this is the first bibliometric study of acupuncture for pain management. In this study, we retrieved data from 4227 studies investigating the application of acupuncture for pain, published between 2010 and 2020. Data from these studies were analyzed using CiteSpace and Excel employing descriptive statistical, co-occurrence and cluster analyses.

We found a general increasing trend in acupuncture for pain publications from 2010 to 2020. The trend of increase in articles published can be divided into the following three stages: (1) the number of articles increased rapidly in 2010, reaching a first slight peak, and then declined in 2012; (2) number of articles increased steadily from 2012 to 2015, and decreased from 2015 to 2016; (3) the period from 2016 to 2019 was a rapid development period and reached a second peak in 2019. This trend was consistent with that observed in other research fields and can be well explained by the increased attention of researchers in this field.14

The top 10 academic journals published 1417 articles, accounting for 33.52% of all articles and suggesting that these top 10 journals had strong interest in articles regarding acupuncture treatment for pain research. According to the analysis of the cited journals, the top ranking for both frequency and centrality was Pain. A systematic review of available therapies for hip and knee osteoarthritis patients, which cited an article in the Pain journal was cited 942 times. This study updates the evidence to suggest that non-pharmacological therapies, including acupuncture, are effective in relieving patients pain symptoms.15 We established that most of these journals are relevant to complementary alternative therapies and pain research. These data will help future scholars to select appropriate journals when submitting articles in related fields.

Less collaborations were observed between countries/regions. Asia, as the birthplace of acupuncture, and developed countries, including the United States, were the main research forces related to acupuncture for the treatment of pain, suggesting that scientific research development is inseparable from economic conditions and academic atmosphere. However, global cooperation has not been formed. Cooperation among other countries was weak except for England where scientific cooperation was relatively close in recent years. This may be attributed to the geographical location of countries. Regarding institutions, it is interesting that Kyung Hee University was not only the most prolific institution but also the highest centrality institution, suggesting that Kyung Hee University is the most important institution for researching acupuncture treatment of pain. However, England and Germany, the top 5 countries with the highest number of publications, did not have any institution in the top 10 list. This may indicate that institutions conducting research in this field are relatively few in the country. In addition, cooperation among institutions was mostly limited to countries such as Beijing University Chinese Medicine, China Medical University and Chinese Academy of Chinese Medical Sciences which were among the top 5 institutions. The close cooperation between China scientific research institutions in recent years may also be one of the reasons for the increase in the number of articles published each year.

All of the top 5 active authors published at least 30 articles. A study conducted by Ernst et al, cited 101 times, suggested that apart from neck pain, there is little convincing evidence that acupuncture is effective in reducing pain.16 However, Zhang et al proposed that electroacupuncture combined with low dosages conventional analgesics can provide effective pain control.8 In addition, cooperative relationships among authors are largely confined to their respective institutions. This demonstrates that several authors tend to work with stable collaborative teams, and that cooperative networks for researchers in this field are highly correlated with the cooperative networks of corresponding institutions. Considering the co-cited authors, the top 5 authors with at least 383 co-citations made significant contributions to the field of acupuncture analgesia. A comprehensive analysis found that MacPherson H and Kong J were core strength researchers and their research had an important influence on the development of acupuncture treatment of pain. MacPherson H is mainly engaged in the evaluation of the effectiveness and safety of acupuncture, and the neuroimaging research on the mechanism of acupuncture. In 2010, MacPherson H and colleagues present an updated reporting guideline, which stands for Revised Standards for Reporting Interventions in Clinical Trials of Acupuncture.17 Kong J mainly focuses on the research of acupuncture analgesia. For example, a study in 2020 identified the neural marker of functional magnetic resonance imaging-based migraine and examined its association with acupuncture treatment.18

Co-citation suggests that the cited literature and corresponding research are related in content, and the literature usually contains high-quality content which has significant influence in a particular field of research. Moreover, the relationship between literature co-citation is likely to change with time. The top 1 reference by frequency is a meta-analysis of individual patient data on acupuncture for chronic pain, which confirms the effectiveness of acupuncture for back and neck pain, osteoarthritis, chronic headache, and shoulder pain.5 The top 1 reference by centrality is a randomized controlled trial of acupuncture for chronic shoulder pain, indicating that acupuncture is an effective alternative to conventional orthopedic treatment for this condition.10 In addition, the extracted terms according to the LLR algorithm emphasize research characteristics and can provide the best results in terms of uniqueness and coverage of cluster-related topics. Cluster # 4 knee osteoarthritis was discovered as a research hotspot of researchers in recent years. For example, Tu et al assessed the efficacy of intensive acupuncture (3 times weekly for 8 weeks) versus sham acupuncture for knee osteoarthritis (KOA) in 2020, based on their previous discussion of the efficacy of acupuncture at different frequencies in the treatment of KOA.19

Through analysing the keyword, research frontiers could be identified. Consistent with previous reports, low back pain in the current study is the most common pain disorder that uses acupuncture as an intervention.14 Randomized controlled trial was the most common research method with the strongest level of evidence to prove its efficacy. However, due to the particularity of the acupuncture operation, double-blinding is difficult to achieve; therefore, the placebo effect has attracted the attention of researchers, and this finding is consistent with our findings in the cited reference. In addition, a burst keyword can indicate cutting-edge research topics and reveal studies that have potential or are of interest. Research history of acupuncture treatment of pain can be drawn from the evolution of keywords used in these articles. For example, human brain and placebo needle were the earliest words to have an impact, while burden was widely carried out in 2017 and has since been used.

This study has used bibliometrics for the first time to perform a visual analysis of literature related to acupuncture for pain, summarized research status and key research forces in this field, and predicted the research trend. In addition, we have used a variety of methods to analyze data, which is suitable for multi-angle interpretation of conclusions. However, this study has limitations that need to be addressed. This study only analyzed the core collection database for Web of Science, because CiteSpace is currently unable to analyze cited references for other databases. It is anticipated that the improvement of this software will enable the expansion of the selection range for databases in the future.

In conclusion, this study reveals hot spots and frontier issues in the field of acupuncture for pain. The findings presented here are expected to promote the optimization of treatment options. The frontier issues in the field presented here will guide funding organizations to refocus their funding priorities.

C&AT, complementary and alternative therapies; LLR, logarithmic likelihood ratio; KOA, knee osteoarthritis.

The following information was supplied regarding data availability: the raw data can be directly obtained from the Web of Science Core Collection (WoSCC) of Thomson Reuters.

Thanks to Prof. Chaomei Chen for opening the use of CiteSpace.

All authors made substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data; took part in drafting the article or revising it critically for important intellectual content; agreed to submit to the current journal; gave final approval of the version to be published; and agree to be accountable for all aspects of the work.

This study was supported by the National Natural Science Foundation of China (no. 81673887), the National Science and Technology Support Program of the ministry of science and technology of China (2013BAI05B00), the Science and technology innovation capacity cultivation project of Shanxi University of Traditional Chinese Medicine (2020PY-LP-03). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

The authors declare that they have no conflicts of interest for this work.

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2. Langley PC. The prevalence, correlates and treatment of pain in the European Union. Curr Med Res Opin. 2011;27(2):463480. doi:10.1185/03007995.2010.542136

3. Gaskin DJ, Richard P. The economic costs of pain in the United States. J Pain. 2012;13(8):715724. doi:10.1016/j.jpain.2012.03.009

4. Cohen SP, Hooten WM. Advances in the diagnosis and management of neck pain. BMJ. 2017;358:j3221. doi:10.1136/bmj.j3221

5. Vickers AJ, Cronin AM, Maschino AC, et al. Acupuncture for chronic pain: individual patient data meta-analysis. Arch Intern Med. 2012;172(19):14441453. doi:10.1001/archinternmed.2012.3654

6. Zhao ZQ. Neural mechanism underlying acupuncture analgesia. Prog Neurobiol. 2008;85(4):355375.

7. Haake M, Mller HH, Schade-Brittinger C, et al. German Acupuncture Trials (GERAC) for chronic low back pain: randomized, multicenter, blinded, parallel-group trial with 3 groups. Arch Intern Med. 2007;167(17):18921898. doi:10.1001/Archinte.167.17.1892

8. Zhang R, Lao L, Ren K, Berman BM. Mechanisms of acupuncture-electroacupuncture on persistent pain. Anesthesiology. 2014;120(2):482503. doi:10.1097/ALN.0000000000000101

9. Cherkin DC, Sherman KJ, Avins AL, et al. A randomized trial comparing acupuncture, simulated acupuncture, and usual care for chronic low back pain. Arch Intern Med. 2009;169(9):858866. doi:10.1001/archinternmed.2009.65

10. Molsberger AF, Schneider T, Gotthardt H, Drabik A. German Randomized Acupuncture Trial for chronic shoulder pain (GRASP) a pragmatic, controlled, patient-blinded, multi-centre trial in an outpatient care environment. Pain. 2010;151(1):146154. doi:10.1016/j.pain.2010.06.036

11. Harris RE, Zubieta JK, Scott DJ, Napadow V, Gracely RH, Clauw DJ. Traditional Chinese acupuncture and placebo (sham) acupuncture are differentiated by their effects on mu-opioid receptors (MORs). NeuroImage. 2009;47(3):10771085. doi:10.1016/j.neuroimage.2009.05.083

12. Kietrys DM, Palombaro KM, Azzaretto E, et al. Effectiveness of dry needling for upper-quarter myofascial pain: a systematic review and meta-analysis. J Orthop Sports Phys Ther. 2013;43(9):620634. doi:10.2519/jospt.2013.4668

13. Lee JH, Choi TY, Lee MS, Lee H, Shin BC, Lee H. Acupuncture for acute low back pain: a systematic review. Clin J Pain. 2013;29(2):172185. doi:10.1097/AJP.0b013e31824909f9

14. Li R, Sun J, Hu H, et al. Research trends of acupuncture therapy on knee osteoarthritis from 2010 to 2019: a bibliometric analysis. J Pain Res. 2020;13:19011913. doi:10.2147/JPR.S258739

15. Zhang W, Nuki G, Moskowitz RW, et al. OARSI recommendations for the management of hip and knee osteoarthritis: part III: changes in evidence following systematic cumulative update of research published through January 2009. Osteoarthritis Cartilage. 2010;18(4):476499. doi:10.1016/j.joca.2010.01.013

16. Ernst E, Lee MS, Choi TY. Acupuncture: does it alleviate pain and are there serious risks? A review of reviews. Pain. 2011;152(4):755764. doi:10.1016/j.pain.2010.11.004

17. MacPherson H, Altman DG, Hammerschlag R, et al. Revised STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA): extending the CONSORT statement. PLoS Med. 2010;7(6):e1000261. doi:10.1371/journal.pmed.1000261

18. Tu Y, Zeng F, Lan L, et al. An fMRI-based neural marker for migraine without aura. Neurology. 2020;94(7):e741e751. doi:10.1212/WNL.0000000000008962

19. Tu JF, Yang JW, Shi GX, et al. Efficacy of intensive acupuncture versus sham acupuncture in knee osteoarthritis: a randomized controlled trial. Arthritis Rheum. 2020.

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[Full text] Research Trends of Acupuncture Treatment | JPR - Dove Medical Press

9 April 2021,A leading market research company, Facts and Factors recently published a research report onComplementary and Alternative Medicine Market by Intervention (Acupuncture, Botanicals, Magnetic Intervention, and Body, Mind & Yoga); by Distribution Channel (E-Training, Direct Contact and Distance Correspondence): Global Industry Perspective, Comprehensive Analysis, and Forecast, 2019 2026. This report is a broad review that includes a detailed overview of the Complementary and Alternative Medicine industry. The report explains the type of Complementary and Alternative Medicine and its application in different verticals of the market with regard to various countries and key regions. The analysis has listed and evaluated all the key players in theComplementary and Alternative Medicine marketand compared them on the basis of different metrics such as annual sales shipments volume, historical growth rates, market revenue, and marketing strategies. On the basis of all these findings, the Complementary and Alternative Medicine industry study report proposes strategic plans to improve market positions for existing market participants.

According to the Facts and Factors research analysis,Global complementary and alternative medicine market to grow at a CAGR of 16.8% and is predicted to grow over USD 190 Billion by 2026. Alternative medicine is a term that refers to medicines that do not establish standard medicines but are used in combination with standard clinical medicines..

This Report covers the manufacturers data, including shipment, price, revenue, gross profit, interview record, business distribution, etc., these data help the consumer know about the competitors better. This report also covers all the regions and countries of the world, which shows a regional development status, including market size, volume, and value, as well as price data.

The report provides a cross-sectional analysis of the Complementary and Alternative Medicine market in terms of market estimates and forecasts for all the segments across different geographic regions. The report covers all the prevalent trends and technologies playing a major role in the growth of the Complementary and Alternative Medicine market over the forecast period. It also highlights various drivers, restraints, and opportunities expected to influence the market growth during the said period.

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Key Questions Answered in this Report

1) What was the impact of COVID-19 on the Complementary and Alternative Medicine market?

2) What is the market size, share of the Complementary and Alternative Medicine market?

3) Who are the top market players in the Complementary and Alternative Medicine market?

4) What are the major regions in the Complementary and Alternative Medicine market?

Top Market Players in the Complementary and Alternative Medicine Market:

In finalizing their position in the Complementary and Alternative Medicine market player positioning, recent events for these firms, such as new solution/product releases, marketing projects, R&D, partnerships, mergers & acquisitions (M&A), regional expansions, and technical innovations, are considered. For all the key stakeholders of the Complementary and Alternative Medicine market value chain and technology ecosystem, the information provided in the Complementary and Alternative Medicine market research report is expected to be beneficial.

This report also provides valuable suggestions for established and new players around the world. Furthermore, the research report includes a precise analysis of business strategy for the growth of the key market players.

For Additional List of Revised Market Players, Request Free Sample Report Here:https://www.fnfresearch.com/sample/complementary-and-alternative-medicine-market-by-intervention-acupuncture

Short Term and Long Term Impact of COVID-19 Pandemic on Businesses

We at Facts and Factors (www.fnfresearch.com)understand how difficult it is for you to plan, strategize, or make business decisions, and as such, we have your back to support you in these uncertain times with our research insights. Our team of consultants, analysts, and experts has developed an analytical model tool for markets that helps us to assess the impact of the virus more effectively on the industrial markets. We are further implementing these insights into our reports for a better understanding of our clients.

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In addition, the study also recommends business penetration plans for potential entrants to the business. Furthermore, the Complementary and Alternative Medicine industry study report has listed the main manufacturers and distributors operating in all the major regions. It is expected that this research and data will enable industry players to improve their networks of market penetration and broaden their geographical scope.

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Complementary and Alternative Medicine Market Size 2020 Analysis with changing market dynamics, current and future market trends, market statistics...

Herbal extracts are a popular item around the world as they are used as herbal medicine, alternative medicine, and food additives same as vanilla, almond, or orange extract in baking. They are liquid solutions made of herbs and alcohol. The herb and alcohol are mixed then the solid part is removed leaving behind the oils and alcohol. This process is known as extraction and thats why it is called herbal extract. They generally have a long shelf life from 1-5 years depending on the base and how you store them. Its recommended to store them in the refrigerator.

As mentioned above they are used for several different purposes. These purposes range from medicinal to cooking. So, what are things you need to know and why should you try one?

Before your try or use any product you should do research beforehand. Weve gone over what it is but there is some other useful information that you should know. Below is a short list of things you need to know about herbal extracts.

Most herbs are used and marketed for their active component. This active part of the herb is what makes a particular herb popular to use in various situations. The research of a particular herb is focused on this special prosperity. An extract of a particular herb is in essence taking a concentrated amount of the active property of the herb which would otherwise require large doses to obtain. When trying or purchasing herbs, researching what the active component is and what the benefits and uses are can help to determine which is right for your particular use.

There are four main types of extracts; liquid extracts, dried powdered extracts, essential oils, and liposomal blends.

Liquid extracts are a very concentrated form of extract and because of this, only a small amount is needed to see the benefits. If you bake then would have seen them in the forms of vanilla, almond, lemon, orange, etc. All things used to give your baked goods more flavor.

Dried powdered extracts these are made by soaking the plant in a solvent that is later evaporated. The concentrated powder is then mixed with whole herb powder and placed in capsules, tablets, or powder form. There are a lot of popular plants used in this form; green tea, kratom, and ginseng are among the most popular. These are the strongest form of herbal extracts even more so than liquid and so a little goes a long way.

Essential oils these are made through a steaming process that allows for the oil to be collected. These are potent and only a few drops are needed. Essential oils are used mainly for aromatherapy purposes.

Liposomal blends Uses the phytochemical components and mixed with fat (liposomes), this is the newest type of preparation. They are usually in capsule or tablet form. The benefit of this type is that the fat added helps to coat the stomach. However, the fat takes up a larger portion of the mixture meaning that you get less of the extract.

There are many other types of herbal extracts. The list provided is the most common type. It is of course recommended that you review the type that you are using. Check the ingredients and make sure that youre purchasing them from a reputable source.

There is a wide range of things herbal extracts are used for. A few examples include:

Cosmetics Medicines Cooking Aromatics Dietary supplements

Many benefits have been purported about herbal extracts throughout time. They have been used in cultures around the world for centuries as natural and alternative medicines. A few reasons why you should give them a try are:

Their health benefits as herbal extracts are concentrated versions of natural herbs, you will gain a lot of health benefits from the active properties in them. These benefits would normally take a large amount of consumption of that particular herb to gain.

Potency plants simply dont contain the same level of potency as their extracted form. Using extracts gives you more for less.

Easy to consume and have versatile uses they dont have to be prepared in the same way as raw herbs would mean that they can be consumed a lot easier and in a more convenient way. They also allow for more versatile use in various products and situations.

The world of herbal extracts is expanding constantly. With more research being done into their properties and uses, the opportunities are endless. It is important though to research and decide for yourself if using extracts is right for you. Whether in your food, for medicinal use, or aromatic purposes knowing what youre using and why can help you to make the best decision for you and your family.

KHTS FM 98.1 and AM 1220 is Santa Claritas only local radio station. KHTS mixes in a combination of news, traffic, sports, and features along with your favorite adult contemporary hits. Santa Clarita news and features are delivered throughout the day over our airwaves, on our website and through a variety of social media platforms. Our KHTS national award-winning daily news briefs are now read daily by 34,000+ residents. A vibrant member of the Santa Clarita community, the KHTS broadcast signal reaches all of the Santa Clarita Valley and parts of the high desert communities located in the Antelope Valley. The station streams its talk shows over the web, reaching a potentially worldwide audience. Follow @KHTSRadio on Facebook, Twitter, and Instagram.

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What You Need To Know About Herbal Extracts And Why You Should Try One - KHTS Radio

Increasing investments in noninvasive treatments for chronic ailments have been increasing potential applications for magnetic therapy devices

Fact.MR, Rockville MD: A new report on the magnetic therapy devices market by market research firm Fact.MR has projected a steady rate of growth through 2021. The covid-19 pandemic has resulted in a moderate slump in the demand for magnetic therapy devices owing to restraints on production activities during the crisis period. High potential for applications in low-cost therapeutics with minimal requirements for hospitalization, are important factors that will support long-term growth prospects for market players.

According to the National Institute of Health, therapeutic devices integrated with permanent magnets are available widely and at low costs, while being fairly easy to use. Magnets are also viewed among consumers as potentially safer alternative to conventional medicine such as analgesic compounds. Health service researchers are pushing to test magnetic therapy devices to minimize the economic burden of chronic musculoskeletal ailments.

Magnets are fairly cheap to produce. Consequently, they are considered ideal for long-term treatments. On the other hand, high-quality scientific evidence in terms of effectiveness, safety and cost is not widely available. As a result, clinical trials on the efficacy of magnetic therapy devices are key to the future of the industry.

Extensive investments for research into alternative medicine and the introduction of technologies such as extremely low frequency magnetic field therapy and microTesla magnetic field therapy, in addition to widespread adoption of magnetic therapy devices among end users is expected to be a major driving factor for revenue generation opportunities in global magnetic therapy devices market, comments a Fact.MR analyst.

Request a report sample to gain detailed insights at https://www.factmr.com/connectus/sample?flag=S&rep_id=3412

Key Takeaways from Fact.MRs Magnetic Therapy Devices Market

Magnetic Therapy Devices Market Prominent Drivers

Magnetic Therapy Devices Market Key Restraints

Discover more about the magnetic therapy devices market with figures data tables and table of contents. You can also find detailed market segmentation at https://www.factmr.com/report/3412/magnetic-therapy-devices-market

Competitive Landscape

Major players in the magnetic therapy devices market include but are not limited to BEMER, EMD Medical Technologies, Swiss Bionic Solutions Holding GmbH, Iskra Medical d.o.o, and Curatronic Ltd.

Leading players in the magnetic therapy devices market are focused on the development and launch of new products in line with medical regulatory standards, to consolidate geographical expansion strategies.

In April 2021, Somavedic Technologies announced the launch of Somavedic Medic Sky a new frequency therapy device aimed towards minimizing side effects of geopathic stress, and electromagnetic fields.

In March 2021, MagVenture announced the launch of its Flow Arm patent-pending technology aimed towards non-invasive brain stimulation positioning applications.

In August 2020, the FDA approved transcranial magnetic stimulation therapy as a viable treatment option for patients with obsessive compulsive disorders.

More Insights on the Magnetic Therapy Devices Market

In its latest report, Fact.MR offers unbiased analysis of the global magnetic therapy devices market. In order to understand the global market potential, its growth, and scope, the market is segmented on the basis of product type (constant energy magnets and pulsed electromagnetic field energy), magnetic field therapy type (microTesla Magnetic Field Therapy and Extremely Low Frequency Magnetic Field (ELF MF) Therapy), end user (hospitals, specialty clinics, and homecare settings), and application (multiple sclerosis, scalp acupuncture, pain management, arthritis, soft tissue injuries, bone fracture healing, and others) across seven regions (North America, Latin America, Europe, East Asia, South Asia, Oceania, and Middle East & Africa).

Explore Fact.MRs Coverage on the Healthcare Domain

Nicotine Replacement Therapy Market: A recent study by Fact.MR on the nicotine replacement therapy market offers a 10-year forecast analysis for the period 2018 to 2028. The study analyzes key trends that are currently determining the growth of the market. This report covers key dynamics, including drivers, restraints, and opportunities for leading market players along with key stakeholders and emerging players.

Skeletal Deformation Correction Market: Fact.MRs extensive coverage on the skeletal deformation correction market offers in-depth insights about the prominent growth dynamics that are likely to aid expansion of growth prospects in the near future. Data has been presented in the form of key segments across prominent geographies, along with important information concerning key manufacturers operating within the industry.

Dental Cements Market: The global dental cements market study published by Fact.MR offers an unbiased analysis of the prominent drivers, opportunities and trends expected to shape future expansion outlook. The report provides a comprehensive assessment on the prominent segments and geographies which are likely to benefit market players in forthcoming years.

About Fact.MR

Market research and consulting agency with a difference! Thats why 80% of Fortune 1,000 companies trust us for making their most critical decisions. We have offices in US and Dublin, whereas our global headquarter is in Dubai. While our experienced consultants employ the latest technologies to extract hard-to-find insights, we believe our USP is the trust clients have on our expertise. Spanning a wide range from automotive & industry 4.0 to healthcare & retail, our coverage is expansive, but we ensure even the most niche categories are analyzed. Reach out to us with your goals, and well be an able research partner.

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Potential in Pain and Bone Treatment Applications Bolsters Prospects of Magnetic Therapy Devices Market: Fact.MR - BioSpace

LONDON, April 09, 2021 (GLOBE NEWSWIRE) -- Based in the UK, SpectrumX is currently raising capital to expand its testing operations alongside other innovative public health products. These include a sanitisation tunnel to disinfect larger crowds attending mass events, new non-alcohol based disinfectants and skincare products.

Antimicrobial resistance (AMR) has been defined as one of the major potential health crises of the 21st century. Medical research has intensified its focus on addressing this issue, however, a bridge has certainly been crossed. Notable bacteria are resistant to nearly all antibiotics and some have even become resistant to all forms of treatment.

AMR occurs naturally, but the misuse and overuse of antibiotics in human medicine and agriculture has accelerated the developmental pace of antibiotic resistance strains. Its currently estimated that 700,000 deaths per year are caused by AMR. The AMR Review predicts that, by 2050, AMR will account for 10,000,000 deaths annually.

Cancer currently accounts for 8,200,000 deaths globally.

AMR doesnt respect lockdowns. From contaminated agricultural runoff water to denser living conditions, our current defences against AMR are worrying. Despite the reduction in international travel, antibiotic resistance has accelerated at an unprecedented rate with Health Secretary Matt Hancock calling it the silent pandemic when speaking with other ministers at the 2018 G7 summit.

A month before our world changed pretty dramatically in 2020, Chief Medical Officer, Dame Sally Davies explained that AMR is ...just as important and deadly as climate change and international terrorism If COVID-19 has taught us one thing, its that these previous warnings require a drastic change in approach.

Although no new class of antibiotics has been brought to the market for decades, new developments in treatments for bacterial infection are providing glints of hope. 43 new antibiotics are being actively researched and tested. 13 are currently at the final phase 3 stage. On the surface this appears promising, however, these treatments tackle infections in the same way those that became resistant do.

Thats why pharmaceutical research is exploring alternative treatments to provide more security against history repeating itself.

One such interesting development is Hypochlorous Acid (HOCL). A highly oxidised, mildly acidic antimicrobial solution, HOCL is produced in the human body when white blood cells attack pathogens. It was first discovered in 1834 and has multiple FDA approvals. It is 300 times stronger than bleach yet completely safe and has broad spectrum antiviral, antifungal and antimicrobial properties.

Historically, HOCL has been overlooked by Big Pharma. This is in large part due to that fact that it has never previously been patent protectable. However, in 2020 the SpectrumX Group in collaboration with Spectrum Antimicrobials announced the completion of the development of SCP-069. SCP-069 is a new class of HOCL-based therapy designed to treat viral, bacterial and fungal infections in the lung and respiratory tract. It was primarily developed to eradicate AMR 'Superbugs.

The ongoing COVID-19 pandemic has accelerated research and investment into HOCL-based therapies. Phase 2 academic clinical trials are currently being led by the Medical University Hospital Innsbruck, testing the nebulised treatment of COVID-19 patients with SCP-069. Nebulisers are medical devices that disperse vapour into the deeper areas of the respiratory system (like lung tissue). Dr Jerry Stonemetz, Medical Director at Johns Hopkins University Hospital explains that:

HOCL has been well researched, published and later cleared by FDA in different therapeutic areas including reduction of topical inflammation and topical pain as well as disinfection of food and food preparation areas. However, none of the above mentioned products have been able to provide stability at lower concentrations for safe use of the product on people. Spectrum Antimicrobials unique and patented formulations provide rapid disinfection in the presence of soil and other organic matter, at concentrations of 0.032% where other HOCL based products have been shown to certainly fail in stability and performance.

The primary endpoints of the study are to demonstrate that inflammation symptoms of patients are reduced, allowing easier breathing after treatment and increased recovery time to reversal of symptoms. With the benefit of successful trial data, several other potential infection treatment possibilities, pertinent to the ongoing AMR crisis, could be investigated. These include pneumonia, bronchitis, asthma, flu and the common cold.

Media contact - E-mail - info@spectrumx.com Company - SpectrumX Holdings Limited

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Why COVID is just the tip of a terrifying, but potentially revolutionary, antibiotic resistant iceberg - GlobeNewswire

STEAMBOAT SPRINGS Local residents might be surprised to learn Steamboat Springs is home to nine respected acupuncturists, which is just one example of the wide variety of health care providers offering complementary wellness services in Routt County.

Whether the therapies are called complementary, non-traditional, natural, integrative, alternative, non-pharmaceutical or holistic, Routt County is home to a growing volume of care options when it comes to healing the human body.

Grace Charles, a naturopathic doctor and licensed acupuncturist in Steamboat Springs for seven years, said non-traditional care options are expanding locally because the health conscious and active community is looking for a variety of treatments for optimal health, strong energy and good sleep. She said the interest in non-traditional medical options is increasing everywhere in the U.S. but certainly in Steamboat Springs.

I think its representative of the patient needs, Charles said. We have a community that is interested in furthering their health care and are going further than whats conventionally considered good health.

As the list of local non-traditional health care options continues to grow, some of the services may be lesser known as available in the community, ranging from prolotherapy injections to placenta medicine to Ayurveda medicine. For example, Routt County is home to approximately 10 chiropractic offices, at least two naturopathic doctors, several herbalists and many massage therapists who offer everything from acupressure to prenatal massage to raindrop techniques. Some other locally available services in complementary care include: allergy elimination techniques, dry needling, hypnotherapy, midwifery, functional medicine, neurofeedback treatments, nutritional therapies, platelet rich plasma injections, rolfing and yoga therapy.

For a small community, we have a lot of services, said Stephanie Loomis, owner of an independent physical therapy practice in Steamboat Springs for 30 years. It gives us more freedom to choose difference types of healing and wellness.

A Steamboat Springs resident for 21 years, full-time technical project consultant and mom, Melanie Timmins was looking for options and collaborative care when struggling to have a second child near age 40. She turned to naturopathic doctor Charles for whole-body help with nutrition, vitamin supplements and exercise for stress relief and good sleep. Although her obstetrician was fantastic, she said, natural medicine filled gaps in her care.

When her second healthy child was born when Timmins was 42, her recovery difference was night and day with a positive post-partum experience after her second childbirth.

(Charles) just added that extra time and extra care for the whole body and really helped me before, during and after pregnancy, said Timmins, adding the combined traditional and non-traditional health care team was an ideal situation.

I hope that can become recognized by the health insurance system, so that non-traditional therapies can be covered as well as traditional, Timmins said.

One downside to natural health care options is not all medical insurance plans or Medicaid cover those services. Some insurance plans may cover services such as acupuncture, and chiropractic or acupuncture visits may be covered under workers compensation or vehicle accidents.

Meg Holpuch, a naturopathic doctor practicing in Steamboat Springs for three years after working in primary care in Oregon, said health care as a team approach where conventional and complementary medicine works hand-in-hand is invaluable for patients.

Its about the network that lifts people up finding health and wellness, said Holpuch, who owns Sumovia Naturopathic Healthcare.

Nicole McGuffin, a doctor of psychology who is licensed and board certified in neurofeedback, has practiced in Steamboat Springs for three years after establishing a clinic in Denver that she later moved to Vail. She said Routt County residents are incredibly open to and seek out alternative methods of treatment here.

This county does feel embracing and progressive of non-traditional healing therapies, McGuffin said.

In addition to her psychology counseling practice specializing in relationships and developmental trauma, McGuffin offers neurofeedback, also known as brain wave training, to help patients with issues such as anxiety, ADHD, cognition, depression, focus, mood, performance and traumatic brain injuries.

Holpuch, who earned a doctorate in naturopathic medicine, said the more health practitioners available to allow patients to stay local for care the better.

When you can get the care you need locally, generally health and wellness is more successful, Holpuch said.

Dr. Jenni McPeek, a board-certified physician specializing in osteopathic manipulative medicine, said the community has a valuable, informal network of complementary wellness professionals who refer patients to each other. Through her practice in Steamboat Springs since 2008, McPeek often refers patients to local complementary health experts.

I love to network as it often takes a few approaches to help someone, said McPeek, who uses gentle hands-on techniques to help the musculoskeletal, nervous and immune systems.

If you are not a candidate for surgery and pharmaceuticals arent a good fit for you, Charles said, then its important to remember you have all of these health care provider options in Steamboat.

Originally posted here:

Complementary health care services continue to expand in Steamboat - Steamboat Pilot and Today

Kolkata: Advocate Sankar Naskar rubbishes misleading and factually incorrect reports published in a section of media without any empirical evidence, and thereby damaging the reputation of Indian Board of Alternative Medicines, and its Officials, Dr. Suresh Kumar Agarwal and Chandan Agarwal.

The Legal Opinion along with annexures of Court Orders and Government Notifications can be viewed here.

Indian Board of Alternative Medicines was a legally constituted Institution duly incorporated under Act XXVI of 1961 of the Government of West Bengal based on the Central Government Act XXI of 1860 and the Literary and Scientific Institutions Act of 1854.

Indian Board of Alternative Medicines conducted courses in alternative systems of medicine, and its activities were appreciated and applauded by several dignitaries and institutions of repute worldwide, including the President of India; Vice-President of India; Prime Minister; Central Ministers; Governors; Chief Ministers; State Ministers; Noble Laureates; International Organizations like United Nations, WHO, UNESCO, etc.

Courses in alternative systems of medicine do not fall under the purview or jurisdiction of Medical Council of India / West Bengal Medical Council, the regulatory body for Modern (Allopathic) Medicines, as per their Letter No. MCI-34(1)/96-Med/10984. Therefore, Indian Board of Alternative Medicines did not require any approval or recognition from Medical Council of India / West Bengal Medical Council to conduct courses in alternative medicines.

Further, the teaching and practice of Alternative Medicines in India can be carried out as per the Ministry of Health and Family Welfare, Government of India Order No. V 25011/276/2009-HR dated 5th May, 2010; Supreme Court of India in the matter of SLP 23572/2009, and Calcutta High Court in the matter of 546 of 1988.

Despite the fact that Indian Board of Alternative Medicines did not require any approval or affiliation of West Bengal Medical Council, as it was conducting courses in alternative systems of medicine only, and not Modern (Allopathic) Medicines, the Government Council had filed a complaint dated 25th May, 2017 alleging that several institutions in West Bengal, including the Indian Board of Alternative Medicines and its courses and certificates awarded, are fake as they are not listed in the Council Register.

Subsequently, a section of media without any empirical evidence published certain misleading information stating that Indian Board of Alternative Medicines was a fake Institution, used forged seals, issued several lakh fake certificates that Officials namely, Dr. Suresh Kumar Agarwal and Chandan Agarwal, were running from law, etc., which were factually incorrect and devoid of substance.

Indian Board of Alternative Medicines was a legally constituted Institution, conducting courses in alternative systems of medicine and awarding its own certificates in the same. It did not require approval of the West Bengal Medical Council in the first place. Subsequent to filing of the Complaint, the Officials of IBAM had approached the Calcutta High Court for Quashing of the FIR proceedings vide Matter No. 1971/2017.

To expedite the hearing of the matter and get a speedy judgment, Dr. Agarwal and Chandan Agarwal approached the Honble Supreme Court in New Delhi, which was pleased to pass an Order on 28th August 2017 vide Diary Number 24565/2017, directing the Calcutta High Court to expeditiously hear the matter. However within a week, they were detained on 6th September, 2017 in New Delhi, before the Calcutta High Court could even complete its hearings and pass a judgment on the Quashing matter filed by the Indian Board of Alternative Medicines.

Therefore, the question of Indian Board of Alternative Medicines being fake, or its Officials running from Law, while they were actually in the middle of following legal procedures, does not arise.

Further, none of the allegations in the Complaint are applicable on Indian Board of Alternative Medicines or its Officials.

In lieu of the above facts, Advocate Sankar Naskar rubbished and junked the misleading and factually incorrect reports published in a section of media without paying attention to the facts and circumstances of the case and without any empirical evidence, thereby damaging the reputation of Indian Board of Alternative Medicines, and its Officials, Dr. Suresh Kumar Agarwal and Chandan Agarwal.

The Legal Opinion along with annexures of Court Orders and Government Notifications can be viewed here.

Disclaimer: This article has been produced on behalf of Indian Board of Alternative Medicines by Mediawire team.

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Advocate rubbishes misleading media reports without any empirical evidence against Indian Board of Altern - Times of India