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Category Archives: Alternative Medicine

Gluconite Reviews Is It Worth The Money or Fake Formula? – GlobeNewswire

Posted: April 17, 2021 at 12:06 pm

Chicago, IL, April 16, 2021 (GLOBE NEWSWIRE) --

Gluconite is a daily remedy for optimizing blood sugar levels and improved sleep. The formula can be found through the official website Gluconite.com, and it is easy to take each night to let the formula work while the user sleeps as it only takes just one cup to target erratic blood sugar overnight.

All supplements have two things in common: a problem and a solution, and Gluconite is one of the more complete and robustly formulated metabolism and sleep support supplements on the market. For Gluconite, the problem is a familiar and important one. Gluconite attempts to address the problem of blood sugar imbalance in people using all potent ingredients in a uniquely blended product that is causing quite a stir in the natural health community. Millions of men and women with diabetes struggle with high blood sugar, which can cause a number of related health problems. High blood sugar can be deadly, according to most modern scientific studies. Gluconite focuses on one particular way to solve this important health issue: sleep. A growing body of scientific research has uncovered an important relationship between nighttime sleep quality and blood sugar regularity.

Gluconite is formulated to provide both metabolic and sleep support to users. The formula is a once-daily dietary supplement that features scientific research from Harvard Medical School, Institute of Medicine of Taiwan and the Phytotherapy Research journal.Taken as a powder, the formula attempts to improve blood sugar by helping people sleep more regularly. The ingredients within the supplement have been studied extensively by scientists in the alternative health sector, and evidence seems to support at least a few of the important claims in the official product website. The formula is compiled inside of a FDA-evaluated and GMP certified facility, which helps to ensure the purity and legitimacy of the supplement.

But Gluconite is currently being sold at a rate as low as $49 per bottle. This may be a bit troubling for some individuals, as it makes it one of the more expensive high-end supplements in the blood sugar formula market, but there is no doubt that in a world where consumers spent a whopping $3.31 trillion dollars in health and wellness last year along (2020), that you often get what you pay for and opting to use cheap supplements likely results in cheap results. However, we do know from experience that some supplements with a high price tag are nevertheless worth the money because the ingredients have high integrity and standards that make it well worth the additional cost. It is also important to remember that blood sugar pills are far more expensive than $69 per bottle and with the bulk buy discount (recommended timeframe for optimal results is three months per the official manufacturer) it is not near as pricey as some of these ineffective formulations out there attempting to tackle one but not all of these three main areas of health like Gluconite. So the high price of this extra strength 15-ingredient supplement means that we want to answer one big question with this review: is Gluconite worth the money?

The answer to this core question is going to be found in the research and other Gluconite reviews simply will not tell you. We want the facts, not the hype and sales pitch so this research is all about does it work and actually revealing what it is they will not tell you before ordering today. Can Gluconite help you improve your metabolism and sleep with only all natural ingredients? Can this formula provide benefits to the metabolism while helping blood sugar levels and nighttime metabolism? Keep reading to learn more and have your Gluconite questions answered.

MUST SEE: Shocking New Gluconite Report is Available! This May Change Your Mind!

What is Gluconite?

By now, everyone knows the time that an individual sleeps is a healing time. The mind may seem like it is at rest, but it is going through many different repairs that are only done during these hours. Getting enough sleep without interruption helps heal the mind's connections that control other processes throughout the body. It is essential to muscle recovery, memory retention, and more. However, the creators behind Gluconite aim to use this time as a way to eliminate blood sugar issues as well.

Working as the user sleeps, Gluconite focuses on improving the metabolism and keeping the user asleep at night. The formula works quickly while the user is resting to keep blood sugar levels balanced the next day. Sleep is essential to the body's general health, which plenty of research backs up. The average person tends to be a lot happier and healthier when they get enough rest through the night, but that is only part of the solution.

The formula is primarily created to help with a diabetes diagnosis, but a doctor does not prescribe it. Instead, the formula is made to be found on the official website, which offers several different packages to save on costs. It doesn't replace any current prescribed remedy with the doctor, but users can integrate it as a preventative measure.

The reason that blood sugar levels are so important to Gluconite is that their management helps with weight loss. Individuals that frequently deal with fluctuations in their blood sugar levels tend to snack much more, adding more calories to the body then it needs. By controlling the appetite, users have a better chance of improving their weight loss.

As users take Gluconite, they will get all of the benefits of the lengthy list of ingredients. Many of these ingredients are considered to be superfoods, and they are not blended with any other supplement today.

How Gluconite Improves Blood Sugar

The reason that Gluconite so effective has to do with the ingredients included in it. Those ingredients are:

The robust lineup of Gluconite ingredients as listed on the nutritional label supplement facts reveal powerful vitamins and minerals that consist of vitamin A (retinyl acetate) (1,000 IU), vitamin C (ascorbic acid) (50 mg), vitamin D as cholecalciferol (1,000 IU), vitamin K from primrose (60 mcg), zinc citrate (5mg), chromium amino acid chelate (10mcg), along with high profile of superfood nutrient extracts in chamomile flower powder extract (500mg), hibiscus powder (1g), passionflower extract (30mg), tryptophan (150mg), gamma-aminobuytric acid (GABA) (500mg), stevia (90% rebaudioside A) (100mg), hops flower powder (30mg), white willow bark extract (367mg) and melatonin (3mg).

Every single ingredient is backed by scientific evidence that is listed below for further evaluation and reading to your heart's liking. To understand exactly why each of these ingredients is important, read it down below to learn a little more about each one.

Willow Bark

Willow bark, which also goes by the name of white willow bark, is primarily included in this formula as a way to promote weight loss. While some researchers have found that using this extract helps with weight loss by reducing the appetite, other people have found that it stimulates thermogenesis. Either of these functions would improve the user's ability to lose weight.

White willow bark can reduce inflammation, especially when it is brought on by diabetes. Some sources say that it is helpful in pain relief as well

Passionflower

Passion flower extract is an adaptogen, helping to alleviate stress on the body. It can reduce both physical and mental stress, improving the users ability to relax at night.

By integrating passionflower into the user's daily diet, it becomes easier to lower cholesterol levels and manage blood sugar in individuals with diabetes. However, further research is needed to show the impact that it may have on blood sugar.

(SPECIAL OFFER) Click Here to Get Gluconite with an Exclusive Discount Price Online

Chamomile

Chamomile is one of the most popular teas to use at bedtime to help the user relax and become more tired. The relaxing effect of this formula is due to benefits it offers as an adaptogen. Along with better sleep, this beverage helps deal with the daily stresses that the body goes through.

Hibiscus

Hibiscus flower has become just as popular as chamomile in teas. The soothing extracts bring relaxation to the user, purging the toxins that can build up in the body and trigger cortisol spikes.

Hops

Hops is a rather unique ingredient to include in a remedy that reduces high blood sugar or promotes better sleep period. Instead, this ingredient is rather helpful to the brain with the way that it supports GABA activity. With the improved health of these neurotransmitters, users can sleep better each night.

As far as blood sugar goes, hops extract does not seem to have any effect.

Tryptophan

Tryptophan is it necessary to the way that the body takes advantage of proteins. It is not typically available in the body normally, which is why it needs to come from outside sources. Most people consume tryptophan in high abundance at least one time a year at Thanksgiving dinner. It is the chemical found in Turkey that makes people feel so tired after eating it. Perhaps that's why it is so helpful in a supplement that is used to promote better sleep.

Melatonin

Unlike tryptophan, melatonin naturally occurs in the body when the users surroundings become darker, causing them to become more tired. However, research has shown that it is safe to take at night to help the body fall asleep. Essentially, it triggers the natural release of the hormone as well, balancing the users circadian rhythm.

Vitamins

Much like a multivitamin, Gluconite includes small amounts of vitamin A comma vitamin C, vitamin D, and vitamin K. All of these vitamins can support balance in the body, extending to sleep. Many diseases have been linked to deficiencies in these vitamins, which just makes more essential.

Minerals

There are only two minerals found in this formula zinc and chromium. Though they're both rather low doses, chromium has been linked to healing and reversal of diabetics. After all, individuals with diabetes tend to have lower levels of chromium than individuals who do not.

Purchasing Gluconite

Even though there are many supplements available on the market today, the only way to order Gluconite for blood sugar, metabolism and sleep support is by going through the official website. A few different packages are offered, providing varying quantities that can work with the user's routine. Even though they all have incredible value, buying more of the product at once will reduce the price per bottle greatly.

Currently, consumers can choose from:

As an added benefit for purchasing multiple bottles at the same time, the only package that incurs a shipping fee is the single-bottle option. If the user finds that this is not the right product for their needs, they have up to 180 days to get a full refund.

Frequently Asked Questions About Gluconite

Are there any side effects associated with Gluconite?

Not at this time. The formula is made with all-natural ingredients that are safe for the body, and they're all tested for purity.

For whom does Gluconite work?

This supplement is meant from both men and women, and individuals of all ages can use it. However, individuals that currently have a prescription regimen with their doctor may want to speak with them before integrating a supplement as well.

How much will users actually have to pay? Is there a subscription?

Users will only have to pay the aforementioned amount for the package that they choose. There is no subscription option, so users will not have to worry about being billed multiple times.

For any other questions or concerns, send an email to the customer service team at support@gluconite.com.

Summary

Gluconite helps consumers who have multiple issues that they want to handle in their body at the same time and are seeking quality support for metabolism, sleep and relaxation. Sleep should be a priority for every person, which is why there are so many ingredients that trigger it healthily. Better sleep has many inherent benefits for the body, especially when it comes to weight loss. However, the creators target weight loss and directly by managing blood sugar levels instead that will induce a deeper sleep per night, resulting in a healthier approach day in and day out towards life.

Our final verdict is that Gluconite might very well be worth the money due to the highly beneficial nutrients that can lower appetite, optimize healthy blood sugar levels and enhance immunity. There are plenty of natural sleep aid supplements available, and there is no shortage of blood sugar formulas within the supplement sector, but Gluconite clearly stands out above the rest for a number of reasons. The great thing about Gluconite is that it combines these two important benefits together and all users have to do is mix a single scoop with six to eight ounces of water approximately 30-60 minutes before bedtime to enjoy the formula's features. Our bodily processes are closely interrelated, and it is important that revolutionary supplements take advantage of the interrelated processes of the body. Gluconite uses a number of completely natural and pure ingredients to help you sleep better at night, which has been scientifically proven to benefit the blood sugar.

Always talk to your doctor if youre experiencing a serious health issue. Blood sugar imbalances can quickly turn into life-threatening conditions if they are left untreated. However, the high cost and significant side effects of blood sugar pills means that a growing portion of high blood sugar sufferers are turning to supplementation. If youre one of these people, consider buying a bottle of Gluconite today due to its unique lineup of ingredients and ability to start optimizing whole body wellness via deeper, more meaningful sleep, resulting in more energy, optimized blood sugar levels and healthy metabolism support.

Scientific References for Gluconite Ingredients

The official Gluconite video presentation is lengthy and quite compelling, and will reference all of the following studies and medical literature for further analysis and evaluation:

(1) Effects of normal meals rich in carbohydrates or proteins on plasma tryptophan and tyrosine ratios. Richard J Wurtman, Judith J Wurtman, Meredith M Regan, Janine M McDermott, Rita H Tsay Jeff J Breu. Am J Clin Nutr. 2003.

(2) Leptins hunger-suppressing effects are mediated by the hypothalamicpituitaryadrenocortical axis in rodents. Rachel J. Perry, Jon M. Resch, Amelia M. Douglass, Joseph C. Madara, Aviva Rabin-Court, Hakan Kucukdereli, Chen Wu, Joongyu D. Song, Bradford B. Lowell, and Gerald I. Shulman. PNAS. 2019

(3) Leptin action on GABAergic neurons prevents obesity and reduces inhibitory tone to POMC neurons. Vong L, Ye C, Yang Z, Choi B, Chua S Jr, Lowell BB. Neuron. 2011

(4) Biologically inactive leptin and early-onset extreme obesity. Wabitsch M, Funcke JB, Lennerz B, Kuhnle-Krahl U, Lahr G, Debatin KM, Vatter P, Gierschik P, Moepps B, Fischer-Posovszky P. N Engl J Med. 2015

(5) Epidemiology of Obesity and Diabetes and Their Cardiovascular Complications. Shilpa N. Bhupathiraju and Frank B. Hu. Circ Res. 2016

(6) The 95%: Why women embrace diets that dont work. Cora J. Wilen. The University of North Carolina. May 2013

(7) Sleep Disorders in the Older Adult A Mini-Review. Ariel B. Neikrug and Sonia Ancoli-Israel. Gerontology. 2010

(8) Association Between Sleep Architecture and Measures of Body Composition. Madhu N. Rao, Terri Blackwell. Sleep. 2009

(9) Sleep deprivation and obesity in adults: a brief narrative review. Christopher B Cooper, Eric V Neufeld, Brett A Dolezal, Jennifer L Martin. BMJ. 2018

(10) Short sleep duration and weight gain: a systematic review. Patel SR, Hu FB. Obesity (Silver Spring). 2008

(11) Impact of sleep and sleep loss on glucose homeostasis and appetite regulation. Kristen L Knutson. Sleep Med Clin. 2007

(12) Sleep and immune function. Luciana Besedovsky, Tanja Lange, and Jan Born. Pflugers Arch. 2012

(13) Sleep problems and risk of all-cause cognitive decline or dementia: an updated systematic review and meta-analysis. Xu W, Tan C, Zou J, et al. Journal of Neurology, Neurosurgery & Psychiatry. 2020

(14) Sleep Duration as a Risk Factor for Cardiovascular Disease- a Review of the Recent Literature. Michiaki Nagai, Satoshi Hoshide, and Kazuomi Kario. Curr Cardiol Rev. 2010

(15) Effects of Serotonergic Activation by 5-Hydroxytryptophan on Sleep and Body Temperature of C57BL/6J and Interleukin-6-Deficient Mice are Dose and Time Related. Jonathan D. Morrow, MD,PhD, Sundeep Vikraman, Mark R. Opp. Sleep. 2009

(16) Brain serotonin, carbohydrate-craving, obesity and depression. Wurtman RJ, Wurtman JJ. Obes Res. 1995

(17) Effects of oral 5-hydroxy-tryptophan on energy intake and macronutrient selection in non-insulin dependent diabetic patients. Cangiano C, Laviano A, Del Ben M, Preziosa I, Angelico F, Cascino A, Rossi-Fanelli F. Int J Obes Relat Metab Disord. 1998

(18) Melatonin Supplementation Lowers Oxidative Stress and Regulates Adipokines in Obese Patients on a Calorie-Restricted Diet. Karolina Szewczyk-Golec, Pawe Rajewski,Alina Woniak. Oxid Med Cell Longev. 2017

(19) A Pre-Exercise Dose of Melatonin Can Alter Substrate Use During Exercise. Cardyl P. Trionfante, Greggory R. Davis, Arnold G. Nelson. Int J Exerc Sci. 2017

(20) Reduced fat mass and increased lean mass in response to 1 year of melatonin treatment in postmenopausal women: A randomized placebo-controlled trial. Amstrup AK, Sikjaer T, Pedersen SB, Heickendorff L, Mosekilde L, Rejnmark L. Clin Endocrinol (Oxf). 2016

(21) The effectiveness of melatonin for promoting healthy sleep: a rapid evidence assessment of the literature. Rebecca B Costello, Cynthia V Lentino,Patricia A Deuster. Nutr J. 2014

(22) Can Magnesium Enhance Exercise Performance? Yijia Zhang, Pengcheng Xun, Ka He. Nutrients. 2017

(23) Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies. Hruby A, Ngwa JS, Renstrm F, Wojczynski MK, Ganna A, Hallmans G, Houston DK, Jacques PF, Kanoni S, Lehtimki T, Lemaitre RN. J Nutr. 2013 .

(24) Vinegar Improves Insulin Sensitivity to a High-Carbohydrate Meal in Subjects With Insulin Resistance or Type 2 Diabetes. Carol S. Johnston, Cindy M. Kim and Amanda J. Buller. Diabetes Care. 2004

(25) Vinegar: Medicinal Uses and Antiglycemic Effect. Carol S. Johnston and Cindy A. Gaas. MedGenMed. 2006

(26) Curcumin Attenuates Oxidative Stress and Activation of Redox-Sensitive Kinases in High Fructose- and High-Fat-Fed Male Wistar Rats. Nachimuthu Maithili Karpaga Selvi, Magadi Gopalakrishna Sridhar, Ramalingam Sripradha. Sci Pharm. 2015

(27) Restorative effects of curcumin on sleep-deprivation induced memory impairments and structural changes of the hippocampus in a rat model. Noorafshan A, Karimi F, Kamali AM, Karbalay-Doust S, Nami M. Life Sci. 2017

(28) Anti-inflammatory Action of Curcumin and Its Use in the Treatment of Lifestyle-related Diseases. Kana Shimizu, Masafumi Funamoto, Tatsuya Morimoto. Eur Cardiol. 2019

(29) Effects of curcumin on learning and memory deficits, BDNF, and ERK protein expression in rats exposed to chronic unpredictable stress. Liu D, Wang Z, Gao Z, Xie K, Zhang Q, Jiang H, Pang Q. Behav Brain Res. 2014

(30) The effects of curcumin on the prevention of atrial and ventricular arrhythmias and heart failure in patients with unstable angina: A randomized clinical trial. Mostafa Dastani, Leila Bigdelu, Masoumeh Salari. Avicenna J Phytomed. 2019

(31) Curcumin: A Review of Its Effects on Human Health. Susan J. Hewlings and Douglas S. Kalman. Foods. 2017

(32) Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Benzie IFF, Wachtel-Galor, Boca Raton. CRC Press/Taylor & Francis. 2011

(33) Immune system effects of echinacea, ginseng, and astragalus: a review. Block KI, Mead MN. Integr Cancer Ther. 2003

(34) Frequency of consuming foods predicts changes in cravings for those foods during weight loss: The POUNDS Lost Study. Apolzan, John W., Candice A. Myers, Catherine M. Champagne, Robbie A. Beyl, Hollie A. Raynor, Stephen A. Anton, Donald A. Williamson, Frank M. Sacks, George A. Bray, and Corby K. Martin. Obesity (Silver Spring, Md.). 2017

(35) Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial. Ebbeling Cara B, Feldman Henry A, Klein Gloria L, Wong Julia M W, Bielak Lisa, Steltz Sarah K. BMJ. 2018

ALSO READ: Gluconite Customer Reviews and User Testimonials: Does It Work For Everyone?

Official Website: https://gluconite.com/

Contact Details: Gluconite

support@gluconite.com

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Gluconite Reviews Is It Worth The Money or Fake Formula? - GlobeNewswire

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Improving Quality of THC-Based Medications Proving to be Lucrative Path for Cannabis Companies – PRNewswire

Posted: at 12:06 pm

PALM BEACH, Fla, April 15, 2021 /PRNewswire/ 2020 was a prosperous year for medical marijuana. In fact, North America medical marijuana market size alone was over USD 8.1 billion in 2020. The medical cannabis market has made some remarkable continued growth in revenues. Medical marijuana, also known as MMJ or medical cannabis, is the marijuana plant and derived products used for the treatment of several illnesses and conditions such as chronic pain and nausea, among others. It is used for various medical purposes such as pain management, epilepsy among others. Various efforts are underway to legalize the use of medical marijuana across major markets in Asia Pacific and Middle East region. Accordingto Global Market Insights the Medical Marijuana Marketsize surpassed USD 22.4 billion in 2020 and is estimated to register over 19.3% CAGR between 2021 and 2027. "The increasing awareness among patients as well as healthcare professionals regarding the benefits of medical marijuana has compelled the regulatory authorities to consider and legalize medical cannabis. Over 30 countries have legalized its medical use through various national programs. Several states in the U.S. have also approved its medical use. However, the drug remains to be identified as illegal at the federal level, irrespective of medical or recreational use, which places it in The Controlled Substance Act of 1970, Schedule I in the U.S. As several research and development initiatives studying the medical use of marijuana are noted across countries, a dynamic legislative scenario is expected during the forecast period." Active companies in news today include: Nextleaf Solutions Ltd. (OTCQB: OILFF) (CSE: OILS), GW Pharmaceuticals plc (NASDAQ: GWPH), Organigram Holdings Inc. (NASDAQ: OGI) (TSX: OGI), Canopy Growth Corporation(NASDAQ: CGC) (TSX: WEED), British American Tobacco p.l.c. (NYSE: BTI).

The Global Market Insights report continued: "Medical marijuana continues to remain widely researched and debated for several decades. The proven medical benefits of specific marijuana-based formulations have led to the commercial approval of multiple medications from The U.S. Food and Drug Administration (FDA). The rising prevalence of cancer has led to an increasing number of patients undergoing chemotherapy and largely experiencing nauseatic conditions. These are studied to be nullified with the help of THC-based medications. THC-based medications are also noted to act as appetite stimulators in cases with wasting syndrome caused owing to AIDS. Further, several THC and CBD-based medications are approved or are undergoing clinical trials for the treatment of neuropathic pain and muscle spasms. As medical marijuana is noted to act as an alternative medicine to its traditional counterparts, an increasing prevalence of illnesses is fueling the market growth."

Nextleaf Solutions Ltd.(OTCQB: OILFF) (CSE: OILS) BREAKING NEWS- Nextleaf Solutions Awarded U.S. Patent for Synthesizing THC-O-Acetate - Nextleaf Solutions Ltd. ("Nextleaf", "OILS", or the "Company"), the world's most innovative cannabis processor, is pleased to announce that the United States Patent and Trademark Office has granted the Company a patent pertaining to a novel synthetic route of modifying Tetrahydrocannabinol ("THC") found in cannabis distillate into a more potent prodrug version of THC-O-acetate.

The Company believes the THC-derived prodrug produced under its patented process may hold significant potential as a therapeutic product due to THC-O-acetate reportedly having pronounced psychedelic effects compared THC, and positive outcomes in the treatment of chronic pain, PTSD, and alcohol use disorder.

"The U.S. continues to be the focal point of our global IP strategy," said Nextleaf CEO Paul Pedersen. "Between operating our cannabinoid innovation lab under strict federal regulations in Canada where cannabis is federally legal and owning one of the largest U.S. patent portfolios of any cannabis company, Nextleaf has the type of robust intellectual property portfolio and scalable commercial platform that large pharmaceuticals and big tobacco companies have already targeted with M&A in 2021."

On March 31, 2021 New York became the 16th state to legalize cannabis. The event increases pressure on the United States to progress federal marijuana reform and it is expected that legislation will be reintroduced and voted on with the Senate Majority Leader Chuck Schumer leading the way.

"This U.S. patent covers our method of THC acetylation and follows our previous patent for synthesizing THC-O-acetate, with improvements to reaction efficiencies," said Nextleaf Solutions R&D Lead, Dr. David Novitski. "Our latest patented method reduces processing time and costs, which are critical when scaling up any drug delivery technology, and THC-O-acetate is no different."

Nextleaf is exploring opportunities to commercialize this patent through IP licensing to a pharmaceutical partner or producing and distributing THC-O-acetate as a therapeutic product under the Company's Health Canada licenses.

"To the best of our knowledge, Nextleaf is the first company in the world, publicly traded or private, to be issued patents for the production of THC-O-Acetate, a specialty molecule not legally available anywhere in the world," said Pedersen. Read more news for Nextleaf Solutions by visiting: https://www.nextleafsolutions.com/press-releases/

In other industry news of note:

Canopy Growth Corporation(NASDAQ: CGC) (TSX: WEED), a world-leading diversified cannabis, hemp, and vaporization device company, recently announced the launch of Vert, the Company's firstQuebec-exclusive brand. The first two strains to launch under the Vert brand are 'Green Cush' and 'Sour Kush', which will be sold via the Socit qubcoise du cannabis (SQDC) in dried flower and pre-roll joint formats. Vert Green Cush is a sativa-dominant strain and Sour Kush is an indica-dominant strain.

"At Canopy Growth, we understand the importance of providing theQuebecmarket with a regionally-exclusive brand," saidKelly Olsen, Vice President of Global Flower Business at Canopy Growth. "Vert cannabis is grown by an experienced community of Quebecois cultivators. We're excited to bring a new offering of local cannabis flower to SQDC shelves."

GW Pharmaceuticals plc (NASDAQ: GWPH), the world leader in the science, development, and commercialization of cannabinoid prescription medicines, along with U.S. subsidiary Greenwich Biosciences, recently announced that the company will present results from completed trials of EPIDIOLEX(cannabidiol) oral solution and nabiximols, known as Sativexoutside of the U.S., at the virtual American Academy of Neurology (AAN) Annual Meeting taking place April 17-22. The company will also present findings of a survey in partnership with the North American Research Committee on Multiple Sclerosis (NARCOMS) the world's largest voluntary, patient-driven multiple sclerosis (MS) registry highlighting the prevalence of cannabis use among people with MS. Additionally, the company will share an update on cannabis-based products, including the evidence-based pathway to FDA approval and related regulatory challenges.

Organigram Holdings Inc. (NASDAQ: OGI) (TSX: OGI) recently announced a C$221 million strategic investment from a wholly-owned subsidiary of BAT (NYSE:BTI). The BAT subsidiary has subscribed for approximately 58.3 million common shares of OGI, which represents a 19.9% equity interest1on a post-transaction basis for total proceeds of approximately C$221 million ("Investment Proceeds") at a price per share of C$3.792, based on a five-day volume weighted average price on the TSX ending March 9, 2021.

Organigram Inc., a leading licensed cannabis producer and a subsidiary of Organigram Holdings Inc. (together, "Organigram" or "the Company"), and BAT have also entered into a Product Development Collaboration Agreement (the "PDC Agreement") pursuant to which a "Center of Excellence" will be established to focus on developing the next generation of cannabis products with an initial focus on CBD. The Center of Excellence will be located at Organigram's indoor facility in Moncton, New Brunswick, which holds the Health Canada licenses required to conduct research and development ("R&D") activities with cannabis products. Both companies will contribute scientists, researchers, and product developers to the Center of Excellence which will be governed and supervised by a steering committee consisting of an equal number of senior members from both companies. Under the terms of the PDC Agreement, both Organigram and BAT have access to certain of each other's intellectual property ("IP") and, subject to certain limitations, have the right to independently, globally commercialize the products, technologies and IP created by the Center of Excellence pursuant to the PDC Agreement.

DISCLAIMER: FN Media Group LLC (FNM), which owns and operates Financialnewsmedia.com and MarketNewsUpdates.com, is a third party publisher and news dissemination service provider, which disseminates electronic information through multiple online media channels. FNM is NOT affiliated in any manner with any company mentioned herein. FNM and its affiliated companies are a news dissemination solutions provider and are NOT a registered broker/dealer/analyst/adviser, holds no investment licenses and may NOT sell, offer to sell or offer to buy any security. FNM's market updates, news alerts and corporate profiles are NOT a solicitation or recommendation to buy, sell or hold securities. The material in this release is intended to be strictly informational and is NEVER to be construed or interpreted as research material. All readers are strongly urged to perform research and due diligence on their own and consult a licensed financial professional before considering any level of investing in stocks. All material included herein is republished content and details which were previously disseminated by the companies mentioned in this release. FNM is not liable for any investment decisions by its readers or subscribers. Investors are cautioned that they may lose all or a portion of their investment when investing in stocks. For current services performed FNM expects to be compensated forty five hundred dollars for news coverage of the current press releases issued by Nextleaf Solutions Ltd. by a non affiliated third party. FNM HOLDS NO SHARES OF ANY COMPANY NAMED IN THIS RELEASE.

This release contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E the Securities Exchange Act of 1934, as amended and such forward-looking statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. "Forward-looking statements" describe future expectations, plans, results, or strategies and are generally preceded by words such as "may", "future", "plan" or "planned", "will" or "should", "expected," "anticipates", "draft", "eventually" or "projected". You are cautioned that such statements are subject to a multitude of risks and uncertainties that could cause future circumstances, events, or results to differ materially from those projected in the forward-looking statements, including the risks that actual results may differ materially from those projected in the forward-looking statements as a result of various factors, and other risks identified in a company's annual report on Form 10-K or 10-KSB and other filings made by such company with the Securities and Exchange Commission. You should consider these factors in evaluating the forward-looking statements included herein, and not place undue reliance on such statements. The forward-looking statements in this release are made as of the date hereof and FNM undertakes no obligation to update such statements.

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Global Innovator and Startup Series with Dr. N Balakrishnan, One of the renowned Personalities in Ayurveda – thepolicytimes.com

Posted: at 12:06 pm

The Policy Times in its uniquely transformative initiative to shed light on the new and pioneering innovation and budding start-ups in India brought the Global Innovator and Startup Series. In one such series Mr. Akram Hoque, Founder-Editor of The Policy Times interviewed Dr. N Balakrishnan, Founder, Integrated International Holistic Cure Centre, India, one of Indias renowned alternative care or more precisely Ayurveda doctor.

Ayurveda has emerged as one of the most sought-after alternative medical care in India and getting rapidly popular in the world. The market value of Ayurveda in India was INR 300 billion in 2018 Billion and is expanding 16% annually and the market is predicted to expand INR 710.87 billion by 2024. In 2018, around 75% of Indian households used Ayurvedic products against only 67% in 2015. It is a promising field and Dr. Balakrishnan is one of the renowned figures in the field.

Full Interview Link: https://www.youtube.com/watch?v=0Sa0cNfVpfQ&t=407s

As an engineer, I used to think human beings are super computers, and if we could go about devising human treatment like servicing computers by aligning opposite elements and making them work in tandem. From a medical point of view, humans have bilateral organs and in Ayurvedic Panchmahabhoot philosophy human body is made up of five basic elements viz. Space, Air, Fire, Water & Earth akin to nucleotides of DNA. At the onset of a disease, the proportion of these five elements could change, and if we could align the elements of both bilateral organs and balance those by making them work in tandem. Thus, I came up with Finger Tip Revolution(FTR) which is a unique method of keeping your fingers of both hands in a particular sequence suited to your constitution and it is different than Reiki or other palm or fingertip treatment. By a comprehensive understanding of nature, divine creator, and human system matrix I could design treatment through mathematical calculation and align the elements of bilateral organs.

I would go with the thousands of-year-old Ayurvedic Panchmahabhoot philosophy human structure and try to find a treatment by realigning macrocosm and microcosm of the human system matrix.

Vision largest, affordable, safe healthcare system out of India.

Mission Transform the healthcare space by providing scientific, effective, easy, and affordable care using age-old Ayurveda knowledge for the benefit of mankind.

Aim is to reach the needy and underprivileged

USP

Recently, I have brought first-of-its-kind water-based bio-film spray Aquanative, with treated herbal water and nano-particles and it is super effective in case of pain, inflammation and provides protection against virus transmission if used within 30 minutes post-vaccination for covid-19 and also effective for other viruses and bacteria for people of any age. The product is ready and our primary market in India but we would also like to have global outreach for this product. We plan to raise 2 crores for initial funding of this product and we aim to capture 1% of the global market(total 50BN) in the next 5 years.

The series was Chaired and Mentored by Dr.P.Sekhar, Chairman Unleashing India, Global Smart City Panel, MTGF.

In his concluding remark Dr. Sekhar brought out an apt comprehensive summary of the current scenario, even today in India Ayurveda is considered alternative medical care but Ayurveda is gaining a steady foothold in the world from Europe to now Middle-East. It is remarkable for Dr. Balakrishnan to venture into the field of engineering to healthcare and medicine. Although Ayurveda time-tested healthcare system it would need a comprehensive and time-appropriate scientific outlook and documentation for it to gain the desired traction. Every claim needs to be validated scientifically for it to gain trust and global acceptance.

For Further Details about his Approach to Ayurveda, Dr. Balakrishnan can be contacted at [emailprotected],[emailprotected]

Summary

Article Name

Global Innovator and Startup Series with Dr. N Balakrishnan, One of the renowned Personalities in Ayurveda

Description

The human body is made up of five basic elements viz. Space, Air, Fire, Water & Earth akin to nucleotides of DNA.

Author

TPT News Bureau

Publisher Name

THE POLICY TIMES

Publisher Logo

Link:

Global Innovator and Startup Series with Dr. N Balakrishnan, One of the renowned Personalities in Ayurveda - thepolicytimes.com

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Complementary and Alternative Medicine Market To Register a Strong Growth Rate and Huge Profits The Courier – The Courier

Posted: at 12:06 pm

TheComplementary and Alternative Medicine Marketresearch report thoroughly explains each and every aspect related to the Global Complementary and Alternative Medicine Market, which facilitates the reports reader to study and evaluate the upcoming market trend and execute the analytical data to promote the business.This report introduces manufacturing process analysis, market share of Complementary and Alternative Medicine industry participants, and industry chain structure.

Complementary and Alternative Medicine Market Insight:

Complementary and alternative medicine market is expected to gain market growth in the forecast period of 2020 to 2027. Data Bridge Market Research analyses the market is growing with the healthy CAGR in the above-mentioned research forecast period. Rising prevalence cancer and other serious diseases worldwide and emerging markets are the factors responsible for the growth of this market.

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The report also inspects the financial standing of the leading companies, which includes gross profit, revenue generation, sales volume, sales revenue, manufacturing cost, individual growth rate, and other financial ratios.

Manufacturers covered in this report are:

Nordic Naturals, Natures Bounty, Unity Woods Yoga Center, Columbia Nutritional, First Natural Brands Ltd., Ayush Ayurveda, Sheng Chang Pharmaceutical Company, Pure Encapsulations, LLC. Quantum-Touch, and Herb Pharm, LLC among others.

Competitive landscape:

Competitive analysis was carried out in the report. This competitive analysis provides insightful data about industry market leaders. The purpose is to help customers understand the existing market participants and potential market participants in the industry. The way the report is made allows customers not only to make the right decisions about the industry but also to maintain steady growth in the industry in the long run. The purpose is to guide customers towards the steady development of their industry growth.

This report includes the following deliverable

TheComplementary and Alternative Medicine marketreport provides successfully marked contemplated policy changes, favorable circumstances, industry news, developments, and trends. This information can help readers fortify their market position. It packs various parts of information gathered from secondary sources, including press releases, web, magazines, and journals as numbers, tables, pie charts, and graphs. The information is verified and validated through primary interviews and questionnaires. The data on growth and trends focuses on new technologies, market capacities, raw materials, CAPEX cycle, and the dynamic structure of the Complementary and Alternative Medicine market.

Major Regions as Follows:

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The report includes accurately drawn facts and figures, along with graphical representations of vital market data. The research report sheds light on the emerging market segments and significant factors influencing the growth of the industry to help investors capitalize on the existing growth opportunities.

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Table Of Contents: Complementary and Alternative Medicine Market

Part 01:Executive Summary

Part 02:Scope of the Report

Part 03:Research Methodology

Part 04:Market Landscape

Part 05:Pipeline Analysis

Part 06:Market Sizing

Part 07:Five Forces Analysis

Part 08:Market Segmentation

Part 09:Customer Landscape

Part 10:Regional Landscape

Part 11:Decision Framework

Part 12:Drivers and Challenges

Part 13:Market Trends

Part 14:Vendor Landscape

Part 15:Vendor Analysis

Part 16:Appendix

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Finally,the Complementary and Alternative Medicine Market report is a source of convincing research reports that can accelerate your business exponentially. The report provides the main regional settings, economic conditions, and the value, benefits, restrictions, generation, supply, demand, and market development speed and figures of the project.

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Complementary and Alternative Medicine Market To Register a Strong Growth Rate and Huge Profits The Courier - The Courier

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Global Complementary And Alternative Medicine Market Share, Growth, Trends And Forecast To 2028 – The Courier

Posted: at 12:06 pm

Trending Report: Complementary And Alternative Medicine Market

The Complementary And Alternative Medicine industry overview, market segment analysis, regional market overview, market defination, limitations, opportunities, industry news and Trends are just some of the topics covered in this report. The report presents the market analysis based on several factors. Different exploratory techniques such as qualitative and quantitative analysis have been used to give data accurately. For a better understanding of the customers, it uses effective graphical presentation techniques, such as graphs, charts, tables as well as pictures.

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Major Market Players Profiled in the Global Complementary And Alternative Medicine Market Report include

The insights in the report are easy to understand and include a graphical representation of the numbers in the form of histograms, bar graphs, pie charts, etc. Components such as market drivers, restraints, challenges, and opportunities for the Complementary And Alternative Medicine market are elaborated in detail. It also presents a complete assessment of the anticipated behaviour about the future market and continuously transforming market scenario. Making an informed business decision is a tricky job; this report gives several strategic business methodologies to support you in making those decisions.

Complementary And Alternative Medicine Market Segmentation:

Based on Type

Based on Application

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Based on Region

North America (NA) US, Canada & Rest of North America

Europe (EU) UK, Germany, France & Rest of Europe

Asia Pacific (APAC) China, Japan, India & Rest of APAC

Latin America (LA) Brazil & Rest of Latin America

Middle East & Africa (MEA) Middle East and Africa

The report provides insights on the following pointers:

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Global Complementary And Alternative Medicine Market Share, Growth, Trends And Forecast To 2028 - The Courier

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Genome Sequencing: An Alternative for Risk Stratification in Myeloid Cancers – Cancer Therapy Advisor

Posted: at 12:06 pm

Whole-genome sequencing was found to provide rapid and accurate genomic profiling for patients with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS), and this technology may be a potential replacement for conventional cytogenetic and sequencing approaches to risk stratification, according to the results of a study published in the New England Journal of Medicine.

Implementing whole-genome sequencing for clinical testing can provide a unified, stable, and extensible platform that minimizes laboratory-specific bias and that can be standardized throughout the world, study researchers stated. Although our study focused on myeloid cancers, many of the advantages of whole-genome sequencing that we observed will directly apply to patients with other cancers, the researchers concluded.

Patients who have AML or MDS often undergo genetic profiling for diagnostic classification and risk assessment. This study tested whether whole-genome sequencing could be streamlined and applied to diagnostic clinical samples in real time. The study included genomic profiles from 263 patients with myeloid cancers, including 235 who had undergone cytogenetic analysis.

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In this study, whole-genome sequencing identified all 40 recurrent translocations and 91 copy-number alterations that were detected using cytogenetic analysis. In addition to these mutations, whole-genome sequencing identified new clinically reportable genomic events in 40 of the 235 patients (17%).

Prospective sequencing was performed on samples taken from 117 consecutive patients in a median of 5 days. These 5 days included 2 days for library preparation, 2 days for sequencing, and less than 1 day for analysis. Results provided new genetic information in 29 patients (24.8%), and risk category changed in 19 patients (16.2%).

According to the researchers, risk prediction based on the whole-genome sequencing results correlated with outcomes. Significantly longer overall survival was observed in the 21 patients with intermediate or favorable risk compared with the 6 patients with adverse risk.

This survival difference was superior to that resulting from the assignment of patients to risk groups on the basis of gene mutations alone, the researchers noted. Although larger studies involving more patients will be required to firmly establish the clinical

performance of whole-genome sequencing, our proof-of-concept study shows that this method has the potential to add prognostic value by expanding risk stratification to more patients, especially for those with inconclusive results on cytogenetic analysis, where whole-genome sequencing could have an immediate effect on treatment decisions.

Disclosure: Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.

Reference

Duncavage EJ, Schroeder MC, OLaughlin M, et al. Genome sequencing as an alternative to cytogenetic analysis in myeloid cancers. N Engl J Med. 2021;384:924-935. doi:10.1056/NEJMoa2024534

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Genome Sequencing: An Alternative for Risk Stratification in Myeloid Cancers - Cancer Therapy Advisor

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INOVIO’s COVID-19 Vaccine Candidate, INO-4800, Provides Broad Cross-reactive Immune Responses In Humans Against Variants of Concern – BioSpace

Posted: at 12:06 pm

PLYMOUTH MEETING, Pa., April 15, 2021 /PRNewswire/ --Inovio (NASDAQ:INO), a biotechnology company focused on rapidly bringing to market precisely designed DNA medicines to treat and protect people from infectious diseases, and cancer, today announced the results of a study focusing on the human immune responses induced by INOVIO's DNA vaccine candidate for COVID-19, INO-4800, against variants of concern. The results showed that INO-4800 induced a robust T cell response against all spike protein variants tested, which the company believes will be key in providing protection against SARS-CoV-2 variants, in addition to providing similar levels of neutralizing activity against both the UK and Brazilian variants as those against the original strain. The study, entitled "INO-4800 DNA Vaccine Induces Neutralizing Antibodies and T cell Activity Against Global SARS-CoV-2 Variants," has been submitted for peer review and can be viewed at https://www.biorxiv.org/content/10.1101/2021.04.14.439719v1.

Dr. J. Joseph Kim, INOVIO's President & CEO, said, "These results are consistent with our expectation that INO-4800, which was found to be well-tolerated and able to produce a balanced immune response in our Phase 1 trial, is able to generate both neutralizing antibodies and robust T cell responses both of which will be essential to protect against the emerging variants of concern."

Regarding INO-4800 development Dr. Kim said, "We will report Phase 2 results in 2Q, and, with FDA concurrence, expect to move into Phase 3 in the second quarter of this year. Our COVID vaccine's projected safety profile, its stability at room temperature for more than a year, and likely ability to safely boost numerous times positions INOVIO's COVID-19 vaccine as an important factor in addressing the virus in its pandemic and endemic states."

In the study, clinical samples were collected at varying timepoints post-immunization from subjects in INOVIO's Phase 1 US-based INO-4800 clinical trial. Antibodies capable of neutralizing activity were measured against the spike protein variants tested, including B.1.1.7 (UK variant), B.1.351 (South African variant) and P.1. (Brazilian variant). The study showed the T cell responses induced by INO-4800 vaccination were fully maintained against the UK, South African and Brazilian variants when compared to the T cell responses to the original Wuhan strain. The neutralization levels of INO-4800 against South Africa and UK variants were reduced to the levels similar to the previous reports of mRNA or viral vector vaccines. Furthermore, despite recent reports showing a reduction in neutralizing activity against the Brazilian variant by the mRNA or viral vector vaccines, INO-4800 generated robust neutralizing antibodies at levels against Brazilian variant which were comparable to those against the Wuhan strain. Taken together with the data showing the maintenance of T cell activity, the results reported in this study provide a comprehensive overview of cross-reactive cellular and humoral immune responses against SARS-CoV-2 variants for INO-4800 vaccinated individuals that may be important for protection against variant strains of SARS-CoV-2.

Collectively, the studies showcase how the combination of robust T cell responses in conjunction with neutralizing antibody responses provide an important defense against both emerging and potential future viral variants, exhibiting broad protection against the virus and less impacted by the mutational changes a virus may undergo.

About INO-4800

INO-4800 is INOVIO's DNA vaccine candidate against SARS-CoV-2, the novel coronavirus that causes COVID-19. Composed of an optimized DNA plasmid, INO-4800 is delivered directly into cells in the body via a proprietary smart device to produce a robust and tolerable immune response. INO-4800 is the only nucleic-acid based vaccine that is stable at room temperature for more than a year, at 37o C for more than a month, has a five-year projected shelf life at normal refrigeration temperature and does not need to be frozen during transport or storage all of which are important considerations when preparing for mass immunizations.

About INOVIO's DNA Medicines Platform

INOVIO has 15 DNA medicine clinical programs currently in development focused on infectious diseases, cancer and HPV-associated diseases. DNA medicines are composed of optimized DNA plasmids, which are small circles of double-stranded DNA that are synthesized or reorganized by a computer sequencing technology and designed to produce a specific immune response in the body.

INOVIO's DNA medicines deliver optimized plasmids directly into cells intramuscularly or intradermally using INOVIO's proprietary hand-held smart device called CELLECTRA. The CELLECTRA uses a brief electrical pulse to reversibly open small pores in the cell to allow the plasmids to enter, overcoming a key limitation of other DNA and nucleic acid approaches, such as mRNA. Once inside the cell, the DNA plasmids enable the cell to produce the targeted antigen, which is processed naturally in the cell and triggers the desired T cell and antibody-mediated immune responses. INOVIO's DNA medicines do not interfere with or change in any way an individual's own DNA. The advantages of INOVIO's DNA medicine platform are how fast DNA medicines can be designed and manufactured; the stability of the products, which do not require cold storage or transport; and the robust immune response, safety profile, and tolerability that have been observed in clinical trials.

With more than 3,000 patients receiving INOVIO investigational DNA medicines in more than 7,000 applications across a range of clinical trials, INOVIO has a strong track record of rapidly generating DNA medicine candidates with potential to meet urgent global health needs.

About INOVIO

INOVIO is a biotechnology company focused on rapidly bringing to market precisely designed DNA medicines to treat and protect people from infectious diseases, cancer, and diseases associated with HPV. INOVIO is the first and only company to have clinically demonstrated that a DNA medicine can be delivered directly into cells in the body via a proprietary smart device to produce a robust and tolerable immune response. Specifically, INOVIO's lead candidate VGX-3100 met primary and secondary endpoints for all evaluable subjects in REVEAL 1, in the first of two Phase 3 trials for precancerous cervical dysplasia, demonstrating ability to destroy and clear both high-grade cervical lesions and the underlying high-risk HPV 16 and 18. INOVIO is also evaluating INO-4800, a DNA vaccine candidate against COVID-19, in a Phase 2 clinical trial in the U.S., as well as Phase 2 trials in China and South Korea. Partners and collaborators include Advaccine, ApolloBio Corporation, AstraZeneca, The Bill & Melinda Gates Foundation, Coalition for Epidemic Preparedness Innovations (CEPI), Defense Advanced Research Projects Agency (DARPA)/Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense (JPEO-CBRND)/Department of Defense (DOD), HIV Vaccines Trial Network, International Vaccine Institute (IVI), Kaneka Eurogentec, Medical CBRN Defense Consortium (MCDC), National Cancer Institute, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Ology Bioservices, the Parker Institute for Cancer Immunotherapy, Plumbline Life Sciences, Regeneron, Richter-Helm BioLogics, Thermo Fisher Scientific, University of Pennsylvania, Walter Reed Army Institute of Research, and The Wistar Institute. For more information, visit http://www.inovio.com.

CONTACTS:

Media: Jeff Richardson, 267-440-4211, jrichardson@inovio.comInvestors: Ben Matone, 484-362-0076, ben.matone@inovio.com

This press release contains certain forward-looking statements relating to our business, including our plans to develop DNA medicines and in particular our clinical work relating to INO-4800 and its potential effectiveness against SARS-CoV-2 variants, our expectations regarding our research and development programs, including the planned initiation and conduct of preclinical studies and clinical trials and the availability and timing of data from those studies and trials, and our ability to successfully manufacture and produce large quantities of our product candidates if they receive regulatory approval. Actual events or results may differ from the expectations set forth herein as a result of a number of factors, including uncertainties inherent in pre-clinical studies, clinical trials, product development programs and commercialization activities and outcomes, our ability to secure sufficient manufacturing capacity to mass produce our product candidates, the availability of funding to support continuing research and studies in an effort to prove safety and efficacy of electroporation technology as a delivery mechanism or develop viable DNA medicines, our ability to support our pipeline of DNA medicine products, the ability of our collaborators to attain development and commercial milestones for products we license and product sales that will enable us to receive future payments and royalties, the adequacy of our capital resources, the availability or potential availability of alternative therapies or treatments for the conditions targeted by us or our collaborators, including alternatives that may be more efficacious or cost effective than any therapy or treatment that we and our collaborators hope to develop, issues involving product liability, issues involving patents and whether they or licenses to them will provide us with meaningful protection from others using the covered technologies, whether such proprietary rights are enforceable or defensible or infringe or allegedly infringe on rights of others or can withstand claims of invalidity and whether we can finance or devote other significant resources that may be necessary to prosecute, protect or defend them, the level of corporate expenditures, assessments of our technology by potential corporate or other partners or collaborators, capital market conditions, the impact of government healthcare proposals and other factors set forth in our Annual Report on Form 10-K for the year ended December 31, 2020, and other filings we make from time to time with the Securities and Exchange Commission. There can be no assurance that any product candidate in our pipeline will be successfully developed, manufactured or commercialized, that final results of clinical trials will be supportive of regulatory approvals required to market products, or that any of the forward-looking information provided herein will be proven accurate. Forward-looking statements speak only as of the date of this release, and we undertake no obligation to update or revise these statements, except as may be required by law.

View original content:http://www.prnewswire.com/news-releases/inovios-covid-19-vaccine-candidate-ino-4800-provides-broad-cross-reactive-immune-responses-in-humans-against-variants-of-concern-301269572.html

SOURCE INOVIO Pharmaceuticals, Inc.

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INOVIO's COVID-19 Vaccine Candidate, INO-4800, Provides Broad Cross-reactive Immune Responses In Humans Against Variants of Concern - BioSpace

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Complementary and alternative medicine therapies and COVID-19: a systematic review – DocWire News

Posted: April 11, 2021 at 5:41 am

This article was originally published here

Rev Environ Health. 2021 Apr 12. doi: 10.1515/reveh-2021-0012. Online ahead of print.

ABSTRACT

OBJECTIVES: Despite the high prevalence of coronavirus and various treatment approaches, including complementary and alternative medicine (CAM), there is still no definitive treatment for coronavirus. The present study aimed to evaluate the effect of CAM interventions on COVID-19 patients.

CONTENT: Four databases (Web of Science, PubMed, Scopus, and EMBASE) were searched from the inception of databases until July 16, 2020. Keywords included complementary and alternative medicine therapies and Coronavirus.

SUMMARY AND OUTLOOK: Of the 1,137 studies searched, 14 studies performed on 972 COVID-19 patients entered the systematic review final stage. The results showed that different CAM interventions (acupuncture, Traditional Chinese medicine [TCM], relaxation, Qigong) significantly improved various psychological symptoms (depression, anxiety, stress, sleep quality, negative emotions, quality of life) and physical symptoms (inflammatory factors, physical activity, chest pain, and respiratory function) in COVID-19 patients. The results showed that various CAM interventions have a positive effect on improving the various dimensions of coronavirus disease but since there are few studies in this regard, further studies using different CAM approaches are recommended.

PMID:33838089 | DOI:10.1515/reveh-2021-0012

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Complementary and alternative medicine therapies and COVID-19: a systematic review - DocWire News

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Antibiotics need further study in cancer treatments – Chicago Daily Herald

Posted: at 5:41 am

You might be surprised to learn that a cancerous tumor is not a single set of cells and some of these tumor cells are more prone to spread to different parts of the body. They are the reason for cancer metastasizing. That subset of tumor cells are known as cancer stem cells and they also are more resistant to anti-cancer medications and radiation therapy.

Recent medical studies have shown cancer stem cells seem to be sensitive to common medications and some dietary supplements. With these therapies, their ability to metastasize may be reduced by as much as 90%. As a result, some researchers suggest cancer therapy should also include therapies that target cancer stem cells.

Cancer stem cells, or CSCs, are a small subpopulation of cells within tumors with capabilities of self-renewal, differentiation and tumorigenicity. The clinical relevance of CSCs demonstrates that CSCs quickly develop resistant to chemotherapy and radiation treatment. CSCs were first described by John Dick in 1994. He discovered that CSCs are slower growing than other tumor cells. Traditional anti-cancer therapies focus on fast-growing cells so it is not unusual for CSCs to "escape" and travel to other parts of the body.

Dick stated that "to get rid of the cancer, you have to find ways of eliminating the stem cells." CSCs may be susceptible to common antibiotics.

All cells contain a unique organelles called mitochondria. It is in the mitochondria that much of the energy used in the cell is made. Both the cell and its mitochondria independently make needed proteins through a protein-based "machine" termed a ribosome. Ribosomes of the cell and the mitochondria are quite different. Indeed, mitochondrial ribosomes are more related to bacterial ribosomes than cellular ribosomes. Some antibiotics kill bacteria by inactivating their ribosomes and there is some research indicating these antibiotics, by the same mechanism, affect the mitochondrial ribosomes of CSCs.

One study published in the medical journal Aging demonstrated that two antibiotics and vitamin C reduced propagation of CSCs by 90%. This was a study done in test tube (in vitro) but the results are compelling. The two antibiotics, doxycycline and azithromycin, bind to CSCs ribosomes at different sites. Vitamin C enhances the effects of the antibiotics. The end result dramatically reduces the metabolic activity of the CSCs, reducing their ability to metastasize.

An additional benefit of azithromycin is that, by a different mechanism, it may reduce the ability of CSCs to survive. Another, less well-known antibiotic, salinomycin (Chemistry, 2020), induces CSCs death by forcing the cells to accumulate toxic levels of iron.

The clinical trials for antibiotics and CSCs is limited but positive. However, given the low toxicity associated with these antibiotics and the potential gain for cancer patients, antibiotic therapy should be considered in combination with chemotherapy, radiation therapy and even surgery. In the fight against cancer, no stone should be left unturned.

Dr. Patrick Massey is medical director of complementary and alternative medicine at Alexian Brothers Hospital Network, and president of ALT-MED Medical and Physical Therapy, 1544 Nerge Road, Elk Grove Village.

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Integrative Health or Complementary and Alternative Medicine Market Emerging Trends and Technology 2021 to 2026 Arab Yoga Foundation (AYF), Soul…

Posted: at 5:41 am

The report gives definite information about Integrative Health or Complementary and Alternative Medicine Market development, market size, CAGR, top driving key players and detailed investigation about market patterns. It assists with upgrading the business procedures, and to develop business opportunities.Integrative Health or Complementary and Alternative MedicineMarket research report shows the latest market insights, current situation analysis with upcoming trends and breakdown of the products and services. This report contains Market segmentation on the basis of its types, applications and regions.

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The report presents the market competitive landscape and a corresponding detailed analysis of the major vendor/key players in the market. Top Companies in the Global Integrative Health or Complementary and Alternative Medicine Market: Arab Yoga Foundation (AYF), Soul Warrior, Sukoun, Aura Wellness, Intouch Clinic, Landmark Fitness Ltd., Osana Family Wellness, Cairo Osteopathy, Blue Tree Clinics, House of Nature Medical Center, Zen Yoga, Salmiya SKY Meditation Centre, Jordan Chiropracti and others.

Global Integrative Health or Complementary and Alternative Medicine Market Split by Product Type and Applications:

This report segments the global Integrative Health or Complementary and Alternative Medicine market on the basis of Types are:

Traditional Alternative Medicine & Botanicals

Mind Healing

Body Healing

Sensory Healing

On the basis of Application, the Global Integrative Health or Complementary and Alternative Medicine market is segmented into:

Cardiovascular Diseases (CVDs)

Obesity

Diabetes

Infertility

Others

Regional Analysis For Integrative Health or Complementary and Alternative Medicine Market:

For comprehensive understanding of market dynamics, the global Integrative Health or Complementary and Alternative Medicine market is analyzed across key geographies namely: United States, China, Europe, Japan, South-east Asia, India and others. Each of these regions is analyzed on basis of market findings across major countries in these regions for a macro-level understanding of the market.

Influence of the Integrative Health or Complementary and Alternative Medicine market report:

-Comprehensive assessment of all opportunities and risk in the Integrative Health or Complementary and Alternative Medicine market.-Integrative Health or Complementary and Alternative Medicine market recent innovations and major events.-Detailed study of business strategies for growth of the Integrative Health or Complementary and Alternative Medicine market-leading players.-Conclusive study about the growth plot of Integrative Health or Complementary and Alternative Medicine market for forthcoming years.-In-depth understanding of Integrative Health or Complementary and Alternative Medicine market-particular drivers, constraints and major micro markets.-Favourable impression inside vital technological and market latest trends striking the Integrative Health or Complementary and Alternative Medicine market.

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What Are The Market Factors That Are Explained In The Report?

Key Strategic Developments:The study also includes the key strategic developments of the market, comprising R&D, new product launch, M&A, agreements, collaborations, partnerships, joint ventures, and regional growth of the leading competitors operating in the market on a global and regional scale.

Analytical Tools:The Global Integrative Health or Complementary and Alternative Medicine Market Report includes the accurately studied and assessed data of the key industry players and their scope in the market by means of a number of analytical tools. The analytical tools such as Porters five forces analysis, SWOT analysis, feasibility study, and investment return analysis have been used to analyze the growth of the key players operating in the market.

Key Market Features:The report evaluated key market features, including revenue, price, capacity, capacity utilization rate, gross, production, production rate, consumption, import/export, supply/demand, cost, market share, CAGR, and gross margin. In addition, the study offers a comprehensive study of the key market dynamics and their latest trends, along with pertinent market segments and sub-segments.

Customization of the Report: This report can be customized as per your needs for additional data up to 3 companies or countries or 40 analyst hours.

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