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Doctors at Sanford Health will soon use augmented intelligence to scan electronic medical records for dozens of factors that could indicate a patient suffers from obstructive sleep apnea.

Those 67 indicators include body mass index (BMI), age, gender, medical history, clinical symptoms and blood work, among other factors. The physician also conducts a sleepiness questionnaire asking people how tired they are throughout the day. Combined, the information outputs a score of how likely the patient has the condition that afflicts millions of Americans by reducing airflow as they sleep.

Max Weaver, the Sanford Health business intelligence analyst who developed the tool, said the goal is simple.

Helping physicians provide the best quality of care, he said. This model does that by using mathematical modeling to narrow the population down. Its really from 1 million to perhaps 50,000. That kind of scale.

Kevin Faber, M.D., is chair and medical director of sleep medicine at Sanford Health in Fargo, North Dakota, and the projects provider champion. He said its a powerful way to reduce unneeded testing, maximize the physicians time and help patients.

Its a tool to help identify risk. Its not the diagnosis. It doesnt replace the need for a sleep test. It doesnt replace the need for the sleep consult for many patients. But its a tool that can help the primary care practitioner be ultra-efficient with his or her time, as they have precious few minutes with their patients and need to do the things that have the biggest impact, he said.

This tool will allow them to then identify those patients at highest risk, so we can treat them for a condition that they didnt know they had.

Unlike many medical conditions accompanied by pain, discomfort or visible symptoms that prompt people to go to the doctor, most sleep apnea sufferers are unaware of it, Dr. Faber said.

The problem is we need a way to identify the group of people who dont know they have the condition and therefore dont know to seek care, he said.

Intrinsic sleep disorders like sleep apnea are typically unknown by the patient because theyre happening at a time when the patient cant be aware of it. And the moment they could be aware of it, once they wake up, the problem is instantly gone.

Its especially difficult if the person doesnt have a bed partner or someone who is with them when theyre sleeping to let them know they regularly stop breathing or snore loudly, Dr. Faber said.

There are lots and lots of people who have no clue this is going on, he said of the roughly 1 out of 5 patients who have it.

Which means that we have tens of millions of people in our country alone, including at least hundreds of thousands in the Sanford footprint that likely have at least mild obstructive sleep apnea.

Thats why health care providers need better, more efficient tools that spot possible sleep disorders, so a doctor can quickly and accurately diagnose them and prescribe a treatment, Dr. Faber said.

He likens sleep apnea to being the base, a contributing cause, of a whole pyramid of metabolic, cardiovascular and neurocognitive health problems. When people are finally diagnosed, only then do some realize how much their poor sleep contributed to overall poor health.

They dont know that that untreated sleep apnea is what is causing their blood pressure to be so difficult to control, or their diabetes to be so difficult to manage. That it impacts their depression or their anxiety so much and thats why theyre having a harder time controlling it, Dr. Faber said. Sleeping pills dont help because the issue isnt that you need to sedate your brain. The issue is you cant stay asleep because you stop breathing over and over.

Thats where big data and tools like this AI project come in, he said.

Each persons electronic medical record already stores countless vital signs, laboratory results, medical history and other data. The artificial intelligence filters through all that information and ranks each persons chance of having sleep apnea as low, medium or high. Smoking is a risk factor, for example, but not for others who dont smoke.

If you have only a couple of those risk factors, you would be at very low risk. If you had 50 out of those 67, youd imagine Holy smokes, theyre at a much higher risk. Theres a weighting of each of those risk factors. Each has a different impact, Dr. Faber said.

Besides showing the overall risk, the tool displays the top five factors driving the score in that patient, which will change over time if the person, for example, stops smoking, loses weight or controls their diabetes.

This AI algorithm automatically adjusts all of that, Dr. Faber said. For the primary care provider who wants to know, Why is my patient at high risk? he or she can simply mouse over the icon and theres your top five risk factors for that patient. Six months later those top five might be different. There will be an automatic re-analysis of every patients risk every month.

Once a patient is identified as being at higher risk, the provider may either refer them to the sleep clinic for evaluation and a traditional sleep study or they may order a home sleep test conducted through their primary clinic. These tests monitor the patients sleep to count how many times they stop breathing during the night.

Its not feasible for the number of patients we have in Sanford Health population to administer a traditional sleep study on every patient, Weaver said. So that provider, rather than sifting through hundreds of data points about one patient, let alone all the patients they have, can see whos at the highest risk to administer that sleep apnea test. It really narrows it down.

Patients with mild sleep apnea likely wont need an additional sleep study if the home sleep test identifies the problem and initial treatment is effective and well-tolerated by the patient, Dr. Faber said. That saves them time and money. It also prevents unnecessary delays in treatment along with the additional travel and associated expenses, he said.

The main treatment options were once weight loss and continuous positive airway pressure (CPAP) therapy. Now the options also include oral appliances that move the lower jaw forward, some surgeries and Inspire therapy that uses an implanted device for those who dont tolerate CPAP.

All of this stuff is not to simply identify whos at risk but to find whatever the right treatment for their apnea is, which is going to vary from one person to another, Dr. Faber said.

I have some amazing stories, tear-jerking stories actually, of the success that getting rid of moderate to severe sleep apnea can have on somebodys life who was previously unable to treat it because they couldnt tolerate having a mask on their face.

Weaver has validated the model and received Sanford Health stakeholder approval and now is working with the technology team to add the AI tool to the emergency medical record system. Weaver said hes unaware of anything else like it on the market.

Its a big population health initiative that has the potential to help not only the health and welfare and quality of life of the people in the Sanford footprint, Dr. Faber said. But it also helps to lower the cost of care because fewer people have uncontrolled diabetes, hypertension, heart attacks and strokes, all those things that cost the health system, the health plan and therefore individual patients more money.

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Sleep apnea AI tool uses 0s and 1s to increase ZZZs - Sanford Health News

The Qraft AI-Enhanced US Large Cap Momentum ETF (NYSE:AMOM), an exchange-traded fund driven by artificial intelligence, has sold a majority of its holdings in Facebook Inc. (NASDAQ:FB) and Walmart Inc. (NYSE:WMT), while loading up on shares in AMC Entertainment Inc. (NYSE:AMC).

What Happened: The ETFs latest portfolio after rebalancing in early July showed that the fund has also sold major chunks ofits holdings, or entirely divested,in home retailer Home Depot Inc. (NYSE:HD), software company Adobe Inc. (NASDAQ:ADBE) and chipmaker Texas Instruments Inc. (NASDAQ:TXN).

The fund has a history of accurately predicting the price movements of electric vehicle makerTesla Inc.'s (NASDAQ:TSLA) shares.

The ETF now has online dating services provider Match Group Inc. (NASDAQ:MTCH), cybersecurity solutions company Fortinet Inc. (NASDAQ:FTNT) and auto parts retailer OReilly Automotive Inc. (NASDAQ:ORLY) as its three largest investments.

Match Group has a 3.65% weighting in the AMOM portfolio, followed by Fortinet and OReilly with 3.5% weighting each.

The other two stocks that make up the top five holdings in AMOM include auto parts retailer AutoZone Inc. (NYSE:AZO) with a 3.1% weighting and enterprise technology company Zebra Technologies Corp. (NASDAQ:ZBRA) with 2.7%.

AMC Entertainment has beenadded to the portfolio this month with a 2.34% weighting. The movie theater chain's stock is up 2078% year-to-date thanks to a short squeeze conducted by retail investors that refer to themselves as "apes."

Prior to the rebalancing, the ETF had Facebook, Walmart, Home Depot, Adobe and Texas Instruments as its five largest stock holdings.

See Also: Best Exchange Traded Funds

Why It Matters: AMOM, a product of South Korea-based fintech group Qraft, tracks 50 large-cap U.S. stocks and reweighs its holdings each month. The fund uses AI technology to automatically search for patterns that have the potential to produce excess returns and construct actively managed portfolios.

AMOM has delivered year-to-date returns of almost 15.1%, compared to its benchmark the Invesco S&P 500 Momentum ETF (NYSE:SPMO) which has returned 14.4% so far this year.

The fund said last week that it has surpassed an important milestone of $50 million in assets under management (AUM), an increase of nearly 1,500% from its $4.22 million total in August last year.

Price Action: Match Group shares closed almost 2.8% higher in Fridays trading session at $162.63, while Fortinet shares closed 1.5% higher at $256.81.

OReilly Automotive shares closed 1.7% higher in Fridays trading session at $591.65.

Read Next: 5 ETFs To Watch In The Second Half Of 2021

Photo by Samantha Celera on Flickr

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Artificial Intelligence Is On The Side Of Apes? Tesla-Fame's AI-Based ETF Sells Facebook, Walmart And Buys AMC - Markets Insider

The technique will tackle the complexity and size of DNA sequencing datasets and can greatly help in pinpointing key alternations in the genomes of cancer patients

Indian Institute of Technology Madras Researchers has developed an artificial intelligence-based mathematical model to identify cancer-causing alterations in cells.The algorithm uses a relatively unexplored technique of leveraging DNA composition to pinpoint genetic alterations responsible for cancer progression.

The research was led by Prof B Ravindran, Head, RBCDSAI, and Mindtree Faculty Fellow IIT Madras and Dr Karthik Raman, Faculty Member, Robert Bosch Centre for Data Science and AI (RBCDSAI), IIT Madras, and also the Coordinator, Centre for Integrative Biology and Systems Medicine (IBSE), IIT Madras. Shayantan Banerjee, a Masters Student at IIT Madras, performed the experiments and analysed the data. The results have been recently published in the reputed peer-reviewed International JournalCancers.

Explaining the rationale behind this study, Ravindran said, One of the major challenges faced by cancer researchers involves the differentiation between the relatively small number of driver mutations that enable the cancer cells to grow and the large number of passenger mutations that do not have any effect on the progression of the disease.

The researchers hope that the driver mutations predicted through their mathematical model will ultimately help discover potentially novel drug targets and will advance the notion of prescribing the right drug to the right person at the right time.

Elaborating on the need for developing this technique, Dr Raman, said,In most of the previously published techniques researchers typically analysed DNA sequences from large groups of cancer patients, comparing sequences from cancer as well as normal cells and determined whether a particular mutation occurred more often in cancer cells than random. However, this frequentist approach often missed out on relatively rare driver mutations.

Dr Raman further said,Detecting driver mutations, particularly rare ones, is an exceptionally difficult task, and the development of such methods can ultimately accelerate early diagnoses and the development of personalised therapies.

In this study, the researchers decided to look at this problem from a different perspective. The main goal was to discover patterns in the DNA sequences made up of four letters, or bases, A, T, G and C surrounding a particular site of alteration.

The underlying hypothesis was that these patterns would be unique to individual types of mutations drivers and passengers, and therefore could be modelled mathematically to distinguish between the two classes. Using sophisticated AI techniques, the researchers developed a novel prediction algorithm, NBDriver and tested its performance on several open-source cancer mutation datasets.

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IIT Madras develops AI-based algorithm to identify cancer-causing alterations - BSI bureau

Google CEO Sundar Pichai warns that the attack on the open internet has been persisting globally. The company CEO also said that in the upcoming years, the power of quantum computing and artificial intelligence would take over the world.

(Photo : Getty Images/Getty Images for Greentech Festival)BERLIN, GERMANY - SEPTEMBER 16: In this screengrab, Sundar Pichai speaks as part of SWITCH GREEN during day 1 of the Greentech Festival at Kraftwerk Mitte aired on September 16, 2020 in Berlin, Germany. The Greentech Festival is the first festival to celebrate green technology and to accelerate the shift to more sustainability. The festival takes place from September 16 to 18.

In a recent interview withBBC,the CEO said that many countries have been exploiting the free internet for everyone. In addition, there are some of them which limit the information dissemination which is oftentimes the real scenario behind the cameras.

Nowadays, the transition from physical activities to online has been fast-moving, especially since the digital age of the internet is continuously developing. Technological adoption has paved the path for others to access more webs via the internet, but sometimes, it could endanger the users' lives without them knowing.

Internet freedom might be on the tip of our fingers, yet the responsibility in using it is often displaced. Perhaps what Pichai wants to happen is for us to be aware that no one is safe on the internet. Everyone is exposed to the risk of having their data stolen or being suppressed to a lot of misinformation on social media platforms.

Besides warning about the threat circling the web, Pichai also tackled issues like data privacy, taxing technology, and more.

Read Also:Google CEO Sundar Pichai Diet Routine: Why Is He Required of Eating Eggs at This Exact Time?

Back in 2018, the Google manager said that artificial intelligence is more profound than fire and electricity. On Sunday, July 11, The Telegraph reported the same topic involving Pichai.

Pichai noted that AI and quantum computing are the two developments that will have a huge impact on everyone in the future.

Many machines are now capable of copying what humans can do. Surprisingly, some tools can even do tasks better than a normal person. This is what AI does since many activities are considered complicated, the machine is assigned to do them.

If it can do good for humans, there are also some bad impacts that AI could produce. In 2017, Elon Musk said that the "biggest risk" that people face is artificial intelligence. Since artificial intelligence can yield fake outcomes, the South African tycoon mentioned that it's better if the government will regulate its usage.

For the part of quantum computing, some technologists together with the Google CEO support the idea that the said technology will not work for everything. It might be applicable to other methods, but the knowledge about quantum computing might feature new solutions to the world.

In a report by The New York Times viaInc. Magazine,Google boss Sundar Pichai has been receiving a lot of criticisms about his style in leading the company.

Additionally, many employees have been complaining about his slow decision-making which results in delayed action in business. Specifically, it would last for a year until Pichai assigns a particular person to the vacant role at Google. The complainants also mentioned that the company did not acquire Shopify.

Related Article: Alphabet, Google's Q1 Earnings: CEO Sundar Pichai Reveals Hybrid Work Setup, Success in Early 2021

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Written by Joseph Henry

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Google CEO Sundar Pichai Cautions the Dangers of Open Web; AI, Quantum Computing to be Highlight for the Next Few Years - Tech Times

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In movies, theyre the bad guys killer cyborgs with bones of steel and lightning-fast reflexes, perhaps an Austrian accent too. But Peter Scott-Morgan has never been afraid of robots. As a scientist and roboticist by trade, he spent decades researching how artificial intelligence (AI) might transform our lives.

Then, in 2017, Dr Scott-Morgan was diagnosed with motor neuron disease, the same paralysing condition that killed Stephen Hawking. Months after puzzling over his wonky foot falling asleep, he was told he had two years to live.

He had other ideas. To survive, he would turn to the technology he had spent his career researching. He would become the cyborg. Scott-Morgan has now had two major surgeries to help keep himself alive with robotics machine upgrades that breathe for him, help him speak, and hopefully will even see him stand again as the advancing paralysis traps him inside his body. He plans to merge his brain with AI eventually too, so he can speak with his thoughts rather than the flicker of his eyes. And Im OK with giving up some control to the AI to stay me, he says. Though that might change what it means to be human ... Theres a long tradition of scientists experimenting on themselves. But die as a human or live as a cyborg? To me, its a no-brainer.

But what about the rest of us? Is humanity destined to merge with machine? We keep hearing that the robots are coming to take our jobs, how likely are they to stage a coup? And why are Facebook and Elon Musk already building machines to read our thoughts?

Credit:Illustration: Matt Davidson

A century ago, a Spanish scientist mapped the human brain and uncovered a hidden kingdom. As microscopes began to peer deeper into that mass of little grey cells, Santiago Cajal lay bare the wiring within, so dense he called it a jungle. It is from his detailed drawings that the world understood neurons for the first time and how they exchange information in a tangled network, giving rise to the senses, the emotions and possibly even consciousness itself.

Decades later, a philosopher and a young, homeless mathematician wondered if that network could be broken down into the most fundamental binary of logic: true or false. Neurons could, after all, be considered on or off, firing a signal or not. This theory, by Warren McCulloch and Walter Pitts at the University of Chicago, proved to be an incomplete model for the human brain, too simple to capture all the strange magic really going on inside. But it did give rise to the binary code of computers those ones and zeroes now form infinite variations of on or off to tell machines what to do. Scientists have been trying to bring computers closer to human brains, at least in function, ever since.

Because machines interpret the world through this binary code, and algorithms (rules made from that code), they are good at a lot of specific things we find difficult, such as solving complex equations fast (and playing chess better than a grandmaster). Yet they often struggle with the mundane things we, with our more complex, adaptable thinking centres, find easy: recognising facial expressions, making small talk and, most of all, improvising.

To overcome this, machine learning models seek to train computers to categorise and then react to things themselves rather than waiting on human programming. Over the past decade, one such model known as deep learning has charged beyond the rest, fuelling an AI boom. Its why your iPhone can recognise your face and Alexa understands you when you ask her to switch on the lights. And deep learning did it by going back to Cajals neural jungle. The learning is said to be deep because a machine is trained to classify patterns by filtering incoming information through layers of interconnected neuron-like nodes.

Im sorry, Dave, Im afraid I cant do that. In the 1968 sci-fi classic 2001: A Space Odyssey, a computer called HAL (Heuristically programmed ALgorithmic) takes over a spaceship.Credit:Fair Use

While these artificial networks take a staggering amount of data to train compared to a human brain, experts such as Scott-Morgan hope they will only get better and more efficient as computing power increases (it is roughly doubling every two years). Already, AI can translate speech, trade stock, and perform surgery (under supervision). Since his own surgical journey was documented in the British documentary Peter: The Human Cyborg, Scott-Morgan has been upgrading to a very Hollywood cyborg-like interface that uses AI to track the movement of his eyes across its screen with tiny cameras and then offers up phrases for his robot voice to say predictive text based on the letters he has spelt out so far.

As UNSW professor of AI Toby Walsh points out, machines are not limited by biological processing speeds the way humans and animals are. But others suspect that the capability of even this kind of AI is about to hit a wall. At the University of Sheffield, computer scientist James Marshall says deep learning networks are still based on a cartoon of how the [human] brain works. They are not really making decisions, because they do not understand for themselves what matters and what doesnt. That means theyre fragile. To tell a picture of a cat from a dog, for example, an AI needs to sift through a huge trove of images. While it might pick up tiny changes that would escape the notice of a human, such as a few pixels out of place, these tiny changes usually dont matter a lot because we understand the main features that set a cat apart from a dog. But suddenly you change some pixels and the AI thinks its a dog, Marshall says. Or if it sees a drawing of a cat or a cat in real life [in 3D] it might have to start from scratch again.

The tendency of AI, however powerful, to break in unexpected ways is part of the reason those driverless cars we keep being promised are yet to arrive. Machines can be fooled even into seeing things that arent really there driverless cars tricked into accelerating past stop signs when the addition of a few stickers on the sign makes them instead perceive increased speed limits; or facial recognition programs duped into skipping past suspects wearing wigs and glasses.

Any AI network is vulnerable to this kind of manipulation, and if hackers know its weak points they can do more than break it, they can hijack it to perform a new task entirely. Of course, AI can be trained to identify and resist this kind of sabotage too but, at some point, it will encounter a problem it hasnt prepared for.

Perhaps a little paradoxically, some experts say that a way to give deep learning more common sense is to fuse it with the old, more rigid form of AI that came before it, where machines used hard-coded rules to understand how the world worked. Others say deep learning needs to become more flexible yet, writing its own algorithms and programs to perform new functions as it needs to, even testing its actions in the real world through robotics (or at least very good simulators) to help it understand causality. Amazons new line of Alexa assistants look through a camera to better understand the world (and their owners).

But I dont think [deep learning] will ever work for driverless cars, Marshall says. When you have to build a more and more complicated machine for a fairly simple task, maybe the machine is built wrong.

Arnold Schwarzenegger (and his iconic Austrian accent) starred as a killer cyborg in The Terminator franchise.Credit:

Marshall is flying a drone around his lab. Its not bumping into walls, the way drones normally do when trying to distinguish one beige, slab of office wallpaper from another. This drone has a tiny chip in its brain holding an algorithm borrowed from a honeybee. It tells it how to navigate the world as the insect does.

At Marshalls lab in Sheffield, now a company offshoot of his university called Opteran, the team is trying something new modelling machine thinking on animals. Marshall calls it natural intelligence, not artificial intelligence. Autonomy, the kind driverless cars and robot vacuums need to navigate their surrounds, is a solved problem, he says. It happens all the time in the natural world. We require very little brain power ourselves to drive, most of the time were on autopilot.

Bees have a less formidable number of neurons than humans about a million, next to tens of billions and yet they can still perform impressive behaviours: navigating, communicating and problem-solving. Marshall has been mapping their brains, training them to perform tasks such as flying through tunnels and then measuring their neural activity; making silicon models of different regions of their brain according to their function and then converting that into algorithms his machines can follow.

Its like a jigsaw puzzle, Marshall says. We havent mapped it all yet, even those million neurons still interact in really complex ways.

So far, he has converted into code how bees sense the world and navigate it, and is busy finalising algorithms from the decision-making centre of their brains. Unlike Cajol, hes not looking to record all the exquisite detail that keeps the brain alive. We just need how it does the function we want. We dont just reproduce the neurons, we reproduce the computation.

When he first put his bee navigation algorithm in the drone, he was stunned at how much it improved, changing course as people moved around it, as walls came closer. Thats when we saw it could work, he says. But because everyone is focused on deep learning, we decided to make our own company to scale it up.

Marshall is also mapping the brains of ants to improve ground-based robots, imagining a world in which autonomous devices are as common as computers, cleaning and improving the world around us. And as machines get smaller smaller even than the head of a pin or the width of a human hair scientists hope they may help fight disease in the body too, cleaning blood or killing cancer and infection. Perhaps one day these nanobots could even repair the nerves fraying apart in people with motor neuron disease such as Scott-Morgan, or keep humans alive longer.

Marshall hopes to eventually look into the brains of larger animals too, including primates. There scientists might find more complex functions again, beyond just autonomy, and into advanced problem-solving, even moral reasoning. Still, just as Marshall is sure his robot bee is not a real bee, he doubts wed be able to reproduce an entire human brain in silico and fire it up to see if some kind of consciousness springs to life. A lot of this research comes out of that very question: could we just replicate the brain somehow, suppose we had a 3D printer, Marshall says. But the brain isnt just its neurons, its how it all interacts. And we still dont understand it yet.

In his latest book Livewired, US neuroscientist David Eagleman describes in new detail the plasticity of the human brain, where neurons fight for territory like drug cartels. There may even be a kind of evolution, a survival of the fittest being waged within our minds day to day, as new neural connections are forged. Quantum scientists, meanwhile, wonder if reactions are happening inside the brain, at its smallest scale, which we cannot even measure. How then could we ever hope to replicate it accurately? Or upload someones consciousness to a machine (another popular sci-fi plot)?

Will Smith battles another pesky AI that thinks it knows best (and a few thousand robots) in the 2004 film I, Robot.