The ‘absolute limit’ of the human lifespan is 150, scientists say – Newshub

In this latest study scientists used human blood count data from the UK Biobank to calculate a single variable called the 'dynamic organism state indicator' (DOSI), which was "associated with expected variables such as age, illness, and lifestyles".

The more a person's DOSI figure fluctuated over time, the less resilient they were - so less able to recover from health setbacks.

The progressive loss of resilience as people age pointed to 150 as being the absolute upper limit for the human lifespan - and there's nothing we know of yet which can push that back further.

"No dramatic improvement of the maximum lifespan and hence strong life extension is possible by preventing or curing diseases without interception of the aging process, the root cause of the underlying loss of resilience," the study reads.

"The loss of resilience cannot be avoided even in the most successfully aging individuals and, therefore, could explain the very high mortality seen in cohorts of super-centennials characterized by the so-called compression of morbidity."

The 'compression of morbidity' refers to a phenomenon seen amongst centenerains, who live lives generally free of serious illness but die not long after getting sick - their excessive age making them less resilient, so the illness takes them out quicker than it might someone who's still in double-digits.

"The proximity of the critical point revealed in this work indicates that the apparent human lifespan limit is not likely to be improved by therapies aimed against specific chronic diseases or frailty syndrome... We conclude that the criticality resulting in the end of life is an intrinsic biological property of an organism that is independent of stress factors and signifies a fundamental or absolute limit of human lifespan."

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The 'absolute limit' of the human lifespan is 150, scientists say - Newshub