New colorectal cancer risk factor identified

Posted: December 16, 2014 at 5:45 am

PUBLIC RELEASE DATE:

15-Dec-2014

Contact: Kathryn Ryan kryan@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News @LiebertOnline

New Rochelle, NY, December 15, 2014-Adiponectin, a collagen-like protein secreted by fat cells, derives from the ADIPOQ gene. Variations in this gene may increase risk for type 2 diabetes, cardiovascular disease, and various cancers. A new study that links specific variations in the ADIPOQ gene to either higher or lower colorectal cancer risk is published in Genetic Testing and Molecular Biomarkers, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available on the Genetic Testing and Molecular Biomarkers website until January 11, 2014.

Xin Guo, First Affiliated Hospital of Harbin Medical University, China, and Jiaqi Liu, Liuping You, Gang Li, Yuenan Huang, and Yunlong Li, Second Affiliated Hospital of Harbin Medical University, explored the relationship between two polymorphisms in the adiponectin gene and the risk of colorectal cancer in the article "Association Between Adiponectin Polymorphisms and the Risk of Colorectal Cancer." They also showed that these genetic variations may interact with environmental factors, such as red meat intake, to affect cancer risk.

"This paper suggests that adiponectin gene sequence may have significant prognostic value for colorectal cancer," says Kenneth I. Berns, MD, PhD, Editor-in-Chief of Genetic Testing and Molecular Biomarkers, and Director of the University of Florida's Genetics Institute, College of Medicine, Gainesville, FL.

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About the Journal

Genetic Testing and Molecular Biomarkers is an authoritative peer-reviewed journal published monthly online with Open Access options and in print that reports on all aspects of genetic testing, including molecular and biochemical based tests and varied clinical situations; ethical, legal, social, and economic aspects of genetic testing; and issues concerning effective genetic counseling. Genetic Testing and Molecular Biomarkers is the official journal of Genetic Alliance. Complete tables of content and a free sample issue may be viewed on the Genetic Testing and Molecular Biomarkers website.

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New colorectal cancer risk factor identified

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