Common wisdom has long held that each dog year is equivalent to seven human years. But a new equation developed to measure how a dog ages finds the family pup may be a lot older than we realize.
Researchers studying chemical changes to canine DNA found that dogs age very quickly during their first five years and much more slowly later on.
The findings, published recently in the journal Cell Systems, calculate that a 5-year-old dog would be pushing 60 in human years.
Puppies age super quickly, said Trey Ideker, the studys senior author and a professor of genetics at the University of California, San Diego, School of Medicine. By the time a dog is a year old, at a molecular level, hes much more like a 30-year-old human. Retrospectively, we did know these things. It didnt make any sense that the equivalent to a 7-year-old human would be able to have puppies.
Ideker and colleagues noticed that dogs, just like humans, have chemical marks on their DNA, called methylation marks, that change with age.
The genome itself doesnt change with age, Ideker said. "What does change is marks on the genes that control a dog or human's growth pattern."
The methylation marks, or as Ideker calls them wrinkles on the genome, change in predictable ways as we and dogs age.
We are able to quantify this at the molecular level and tell how fast someone is aging, and we can align it across dogs and humans, Ideker said. But we dont know exactly what it all means.
To find the mathematical relationship connecting dog aging to human aging, Ideker and his colleagues studied 104 Labrador retrievers whose ages ranged from weeks-old puppies to 16-year-old dogs.
Let our news meet your inbox. The news and stories that matters, delivered weekday mornings.
When they compared the dog DNA data to information from humans, the researchers came up with a new equation to figure out the dog's comparable human age.
The equation: 16 ln(dog age) + 31 = human age.
For iPhone calculators that have the natural logarithm, or "ln," function, first type in the dog's age. Then hit the "ln" button. Multiply that result by 16; then add 31.
If you're using Googles scientific calculator: First, hit "ln," then type in the dogs age, then equal it out. Next, multiply by 16, and then add 31.
Using that equation:
By this time, dog aging has slowed down, so an 8-year-old dog is like a 64-year-old human.
According to this equation, the average 12-year Labrador lifespan is equivalent to a human living to about 70.
Ideker suspects there will be some variation based on dog breed but that they will all follow a similar pattern.
The new dog-age math has given Ideker some pause when he thinks about taking his own dogs on runs: He now realizes his 6-year-old dog is actually pushing 60 in human years.
Margret Casal, a specialist in veterinary genetics, said the new calculations match what shes observed in her dog patients.
It validates what a lot of other researchers have been saying, said Casal, a professor of medical genetics, pediatrics and reproduction at the University of Pennsylvania School of Veterinary Medicine.
Researchers knew the 1-to-7 comparison was off, but they did not know what the specific relationship was, she added.
It will be interesting to look at different breeds," Casal said. "We know that some smaller breeds live longer and some larger ones dont live quite as long.
For owners hoping to help a beloved dog live as long as possible, Casal offered a few tips:
Lastly, take your dog for yearly wellness visits.
Thats really important, Casal said. I can say as an owner of a dog, sometimes you dont see something is wrong and your vet might be able to see it better.
Linda Carroll is a regular health contributor to NBC News and Reuters Health. She is coauthor of "The Concussion Crisis: Anatomy of a Silent Epidemic" and "Out of the Clouds: The Unlikely Horseman and the Unwanted Colt Who Conquered the Sport of Kings."
Original post:
How old is your dog? New equation shows how to calculate its age in human years - NBC News
- SCARY GHOST ENCOUNTER! (The Hidden) - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- Human Genetics and Genomics: The Science for the 21st Century - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- DNA Research - 07-09-2012 - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- Replying to Equestions on Junk DNA - Video [Last Updated On: September 7th, 2012] [Originally Added On: September 7th, 2012]
- 2013 Rosalind Franklin Young Investigator Awards Announced [Last Updated On: September 8th, 2012] [Originally Added On: September 8th, 2012]
- Jackson Lab CEO Leads From Heart [Last Updated On: September 28th, 2012] [Originally Added On: September 28th, 2012]
- Love of science lifts Hobe Sound teen to genetics conference in Germany [Last Updated On: September 30th, 2012] [Originally Added On: September 30th, 2012]
- Nobel Laureates and Experts Gather to Discuss Genetics and Society [Last Updated On: September 30th, 2012] [Originally Added On: September 30th, 2012]
- Seattle Genetics and Millennium Complete Enrollment in Phase III AETHERA Trial of ADCETRIS® for Post-Transplant ... [Last Updated On: September 30th, 2012] [Originally Added On: September 30th, 2012]
- GENETICS Journal Highlights for October 2012 [Last Updated On: October 2nd, 2012] [Originally Added On: October 2nd, 2012]
- Myriad Genetics Sponsors Cancer Awareness Initiatives in Support of National Hereditary Breast and Ovarian Cancer Week [Last Updated On: October 3rd, 2012] [Originally Added On: October 3rd, 2012]
- Study Says Genetics Of Intelligence Remains A Riddle, For Now [Last Updated On: October 3rd, 2012] [Originally Added On: October 3rd, 2012]
- ORF Genetics to Offer endotoxin- and Animal-free FGFb and mLIF for Stem Cell Research [Last Updated On: October 4th, 2012] [Originally Added On: October 4th, 2012]
- Research and Markets: Human Genes and Genomes. Science, Health, Society Provides Students and Professionals Alike With ... [Last Updated On: October 5th, 2012] [Originally Added On: October 5th, 2012]
- Mosquito genetics may offer clues to control malaria, researchers say [Last Updated On: October 5th, 2012] [Originally Added On: October 5th, 2012]
- Delphi Genetics Grants Merck License for the Use of the StabyExpress™ System [Last Updated On: October 8th, 2012] [Originally Added On: October 8th, 2012]
- This Week in PNAS [Last Updated On: October 10th, 2012] [Originally Added On: October 10th, 2012]
- Outsmarting breast cancer [Last Updated On: October 10th, 2012] [Originally Added On: October 10th, 2012]
- Economics and genetics meet in uneasy union [Last Updated On: October 10th, 2012] [Originally Added On: October 10th, 2012]
- Nurture trumps nature in study of oral bacteria in human twins, study finds [Last Updated On: October 12th, 2012] [Originally Added On: October 12th, 2012]
- Nurture trumps nature in study of oral bacteria in human twins, says CU study [Last Updated On: October 12th, 2012] [Originally Added On: October 12th, 2012]
- Claim That Links Economic Success and Genetic Diversity Draws Criticism [Last Updated On: October 12th, 2012] [Originally Added On: October 12th, 2012]
- Master-builder of the Human Genetics Unit [Last Updated On: October 15th, 2012] [Originally Added On: October 15th, 2012]
- Genetics Society of America announces 2013 award recipients [Last Updated On: October 15th, 2012] [Originally Added On: October 15th, 2012]
- Myriad Genetics to Announce First Fiscal Quarter 2013 Results on Monday, November 5, 2012 [Last Updated On: October 15th, 2012] [Originally Added On: October 15th, 2012]
- Petes Wins Lifetime Achievement Award in Genetics [Last Updated On: October 16th, 2012] [Originally Added On: October 16th, 2012]
- 23andMe Names Christine Castro, Neil Rothstein and Jonathan Ward to Leadership Positions [Last Updated On: October 16th, 2012] [Originally Added On: October 16th, 2012]
- Privately owned genetic databases may hinder diagnosis and bar the way to the arrival of personalized medicine [Last Updated On: November 2nd, 2012] [Originally Added On: November 2nd, 2012]
- Neil Risch - Wiki Article - Video [Last Updated On: November 2nd, 2012] [Originally Added On: November 2nd, 2012]
- GHOST DANCE (The Hidden) - Video [Last Updated On: November 2nd, 2012] [Originally Added On: November 2nd, 2012]
- SCARY GAME - "The Hidden" With Mr.Mitch361, Charlie, and ChildDolphin - Video [Last Updated On: November 2nd, 2012] [Originally Added On: November 2nd, 2012]
- International Academy of Cardiology: Neil Bowles, Ph.D.: GENETIC CAUSES OF CONGENITAL HEART DEFECTS - Video [Last Updated On: November 2nd, 2012] [Originally Added On: November 2nd, 2012]
- The Best Of: "The Hidden" - Video [Last Updated On: November 2nd, 2012] [Originally Added On: November 2nd, 2012]
- MEAT SHIELD (The Hidden) - Video [Last Updated On: November 4th, 2012] [Originally Added On: November 4th, 2012]
- The 10000 Year Explosion: How Civilization Accelerated Human Evolution - , Henry Harpending - Video [Last Updated On: November 4th, 2012] [Originally Added On: November 4th, 2012]
- Humans, chimpanzees and monkeys share DNA but not gene regulatory mechanisms [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- Surprising findings from NHLBI Exome Sequencing Project reported [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- New method helps link genomic variation to protein production [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- Ariosa Diagnostics to Present Clinical Data on the Harmony™ Prenatal Test at American Society of Human Genetics Annual ... [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- ALEX JONES Talks To DAVID ICKE: Human Genetics, Election FRAUD [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- David Icke Exposes ROYAL PAEDOPHILES - Video [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- Alex Jones - David Icke: Human Genetics, The Religion Of Death - Video [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- David Icke - Infowars Election Coverage 2012 - Video [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- David Icke: Human Genetics, The Religion of Death - Video [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- Evening with the UC Davis Genome Center - Oct 6, 2012 - David Segal - Video [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- The Hidden - (Blood For The Blood God, I Must Feed) - Video [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- GHOST ISSUES (The Hidden) - Video [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- The Hidden - (Fart Grenades And Friendly Fire) - Video [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- GHOST ISLAND (The Hidden) - Video [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- Growth Hormone - Video [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- Social Anthropology And Human Origins - Alan Barnard - Video [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- Protein Structural Biology In Biomedical Research. Advances In Molecular And Cell Biology, Volume 22 - Video [Last Updated On: November 7th, 2012] [Originally Added On: November 7th, 2012]
- Exome sequencing: Potential diagnostic assay for unexplained intellectual disability [Last Updated On: November 9th, 2012] [Originally Added On: November 9th, 2012]
- Unexplained intellectual disability explained by state-of-the-art genetic analysis [Last Updated On: November 9th, 2012] [Originally Added On: November 9th, 2012]
- DNA variants explain over 10 percent of inherited genetic risk for heart disease [Last Updated On: November 9th, 2012] [Originally Added On: November 9th, 2012]
- Novel type 2 diabetes genetic study involves 5 major ancestry groups [Last Updated On: November 9th, 2012] [Originally Added On: November 9th, 2012]
- Significant relationship between mortality and telomere length discovered [Last Updated On: November 9th, 2012] [Originally Added On: November 9th, 2012]
- Alex Jones on David Icke 2001 - The Turd - Video [Last Updated On: November 9th, 2012] [Originally Added On: November 9th, 2012]
- David Icke Human Genetics [Last Updated On: November 9th, 2012] [Originally Added On: November 9th, 2012]
- BLINDNESS (The Hidden) - Video [Last Updated On: November 9th, 2012] [Originally Added On: November 9th, 2012]
- Human Genetics, The Religion of Death : David Icke - Video [Last Updated On: November 9th, 2012] [Originally Added On: November 9th, 2012]
- Alex Jones Show - David Icke: Human Genetics, Paedophile Gov., The Religion of Death - Video [Last Updated On: November 9th, 2012] [Originally Added On: November 9th, 2012]
- Human Genetics - Video [Last Updated On: November 9th, 2012] [Originally Added On: November 9th, 2012]
- DAVID ICKE: Human Genetics, The Religion of Death (11/6/2012) - Video [Last Updated On: November 9th, 2012] [Originally Added On: November 9th, 2012]
- Human Genetics: The Basics - Ricki Lewis - Video [Last Updated On: November 9th, 2012] [Originally Added On: November 9th, 2012]
- The Hidden - (Meat Shields Everywhere, Face Of Protection) - Video [Last Updated On: November 9th, 2012] [Originally Added On: November 9th, 2012]
- Leading Genomic Services Company and Its Partners Raise More Than $150,000 in Support of Pediatric Genetics Research [Last Updated On: November 11th, 2012] [Originally Added On: November 11th, 2012]
- Verinata Health Announces New Findings At The American Society Of Human Genetics [Last Updated On: November 11th, 2012] [Originally Added On: November 11th, 2012]
- DAVID ICKE: Human Genetics, The Religion of Death! ALEX JONES [INFOWARS Nightly News] - Video [Last Updated On: November 11th, 2012] [Originally Added On: November 11th, 2012]
- ALEX-JONES-Talks-To-DAVID-ICKE--Human-Genetics,-Election-FRAUD-n-The-Religion-Of-DEATH - Video [Last Updated On: November 11th, 2012] [Originally Added On: November 11th, 2012]
- Illumina Bioninformatics Overview at ASHG 2012 - Video [Last Updated On: November 11th, 2012] [Originally Added On: November 11th, 2012]
- The Hidden - Fun With No Silence [Last Updated On: November 11th, 2012] [Originally Added On: November 11th, 2012]
- David Icke - Human Genetics, The Religion of Death [11/06/2012] - Video [Last Updated On: November 11th, 2012] [Originally Added On: November 11th, 2012]
- Genetics Center takes part in global meet [Last Updated On: November 12th, 2012] [Originally Added On: November 12th, 2012]
- Half Life 2 Mods: The Hidden | Part 4 | TO WIN, OR NOT TO WIN! - Video [Last Updated On: November 12th, 2012] [Originally Added On: November 12th, 2012]
- US-X - Video [Last Updated On: November 12th, 2012] [Originally Added On: November 12th, 2012]
- Personalized Medicine From Genomics and Bioinformatics Highlighted at UCSF Genetics Symposium [Last Updated On: November 14th, 2012] [Originally Added On: November 14th, 2012]
- News in Brief: Highlights from the American Society of Human Genetics annual meeting [Last Updated On: November 14th, 2012] [Originally Added On: November 14th, 2012]
- Star Visitors - Dr. Richard Boylan - Coast to Coast AM Classic - Video [Last Updated On: November 14th, 2012] [Originally Added On: November 14th, 2012]
- Protein Structural Biology In Biomedical Research, Part A - C. Woodward - Video [Last Updated On: November 14th, 2012] [Originally Added On: November 14th, 2012]