Global Display Library Technologies and Affiliated Services Market to 2030 by Type of Technology, Type of Molecule, and Regions -…

DUBLIN--(BUSINESS WIRE)--The "Display Library Technologies and Affiliated Services Market by Type of Technology, Type of Molecule, and Key Geographical Regions, Industry Trends and Global Forecasts: 2021-2030" report has been added to ResearchAndMarkets.com's offering.

This report features an extensive study of the current landscape of display library technologies and services market and the future opportunities associated with such technologies. It features an in-depth analysis, highlighting the capabilities of various stakeholders engaged in this domain.

Biologics are one of the fastest growing classes of therapeutics in the pharmaceutical industry. However, the development of such large molecule drugs is inherently complex, involving elaborate target selection and validation, hit generation, lead selection/optimization and characterization protocols. Of the aforementioned steps, hit (potential drug candidates against validated biological targets) generation is a highly resource-intensive process. In fact, it is estimated that an average of 18 months is spent in generating hits against a validated target.

Additionally, there is an approximate 25% chance of failure in the hit generation to lead identification phase of drug discovery. Over time, a variety of methods/approaches have been developed for the generation of viable therapeutic leads; these include the hybridoma technology, B-cell cloning, transgenic animal-based techniques, in vitro display methods (using phages, ribosomes, mRNA, and cDNA) and cell surface display methods (involving mammalian, yeast, and bacterial cells). Despite being responsible for the development of several successful therapies, the hybridoma and B-cell based hit generation techniques are limited in several aspects; for instance, drugs/drug candidates developed using the aforementioned technologies are often highly immunogenic, and developers also find it difficult to develop and produce stable molecules with noteworthy affinities for their respective targets. As a result, innovator companies have demonstrated a preference for some of the relatively newer hit generation methods, which involve the use of display-libraries.

In modern medical research, display libraries have been successfully employed for the generation of various novel therapeutics and offer certain advantages over conventional drug screening methods, including (but not limited to) the ability to facilitate large-scale, high throughput screening, incorporation of greater diversity in viable lead identification, and eliminating the threat of possible immune response to pharmacological candidates identified through this approach. Out of the available display technologies, those based on phages are the most popular, primarily owing to the simplicity of the selection method they offer and the fact that they can be used to generate hits against several complex antigens.

In addition to other elements, the report features:

Companies Mentioned

Key Questions Answered

Key Topics Covered:

1. PREFACE

2. EXECUTIVE SUMMARY

3. INTRODUCTION

4. MARKET LANDSCAPE: LIBRARY-BASED DISPLAY TECHNOLOGIES AND SERVICES

5. MARKET LANDSCAPE: DISPLAY LIBRARY TECHNOLOGIES AND AFFILIATED SERVICES

6. COMPANY PROFILES

7. CASE STUDY: BIOLOGICS DISCOVERED USING PHAGE DISPLAY METHOD

8. PARTNERSHIPS AND COLLABORATIONS

9. PUBLICATION ANALYSIS

10. PATENT ANALYSIS

11. MARKET SIZING AND OPPORTUNITY ANALYSIS

12. CONCLUDING REMARKS

13. EXECUTIVE INSIGHTS

14. APPENDIX

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Global Display Library Technologies and Affiliated Services Market to 2030 by Type of Technology, Type of Molecule, and Regions -...