Daily Archives: February 9, 2024

Like many captive elephants, Nidia suffered from chronic foot problems. Fissures had formed in the 55-year-old Asian elephants foot pads, and her toenails had cracked and become ingrown. Painful abscesses lingered for months. Nidia had lost her appetite and she was losing weight.

Dr. Quetzalli Hernndez, the veterinarian in charge of Nidias care at a wildlife park in Mexico, was desperate. She decided to try cannabidiol, or CBD, the nonintoxicating therapeutic compound found in cannabis.

For help, Dr. Hernndez reached out to Dr. Mish Castillo, the chief veterinary officer at ICAN Vets, a company engaging in veterinary cannabis education and research in Mexico. To Dr. Castillos knowledge, no one had purposely given an elephant medical cannabis. But he and his colleagues hoped it would reduce Nidias pain and stimulate her appetite, as they had seen the drug do for cats, dogs and other species.

They started low and eventually settled on a dose of 0.02 milligrams of CBD per pound of Nidias weight, which she took daily with a chunk of fruit. Calibrated by weight, the dose is one-tenth to one-fortieth of what Dr. Castillo gives to dogs or cats. Yet it worked.

The first sign that the treatment was effective was when Nidia developed a serious case of the munchies. Within days of starting CBD, she went from finishing just one-third of her food to virtually all of it, and sometimes even went for seconds. Within five weeks, she had gained 555 pounds.

After Nidia began eating, her demeanor changed. She was always known as the grumpy one she used to kick doors, Dr. Castillo said. Within the first week to 10 days of her treatment, she started coming out of her enclosure quicker and was in less of a bad mood.

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Curing Pets With Cannabis as Veterinarians Try CBD and THC - The New York Times

Medical cannabis, often in the form of cannabidiol (CBD) oil, is one of the most recent trends in the human health and wellness world. Unsurprisingly, this trend has made its way to our pets, with a recent study suggesting that 38% of surveyed Danish dog owners routinely gave their pets some form of cannabis product.

Because many people actively promote the use of CBD to support their own health and wellbeing, the use of CBD oil for pets is attracting increased attention from vets and pet owners alike.

Previous studies suggest that 80% of dog owners in the US and Canada had bought cannabis products for their pet. While availability and regulatory differences might account for this variance, it is clear that cannabinoids are regularly being given to pets globally.

It is important to note that CBD doesnt contain the psychoactive substance THC (tetrahydrocannabinol) that is responsible for some of the serious effects seen in pets after accidental ingestion of cannabis and derivatives, so its use wont make your pet high or give them the munchies.

But, is CBD safe for our pets and could it be a useful addition to our pets healthcare regime?

The use of CBD oil by people to support conditions such as chronic pain, migraines, anxiety and epilespy has led many people to consider its use for their pets, who often suffer from similar conditions.

While anecdotal reports of the benefits of CBD use are typically positive, many studies have failed to find an effect. This means that its value as a potential therapeutic aid remains poorly understood.

However, in line with increased interest in CBD to support human health, research is exploring potential benefits for pets, too, with some interesting outcomes.

CBD oil has been shown to significantly reduce the signs of stress in dogs during travel and separation two areas of concern for many pet owners.

For dogs suffering from osteoarthritis, CBD oil resulted in increased activity and decreased pain scores, as assessed by a vet. Indeed, 36% of respondents in the Danish study indicated that they used cannabinoids for pain management in their pets. This group also reported high perceived efficacy of CBD in managing their dogs pain.

For dogs with skin irritation as the result of allergy, CBD reduced itching but not skin damage or lesions. In the Danish study, 11% of respondents reported using CBD to help their dog with allergies, and the perceived outcome was good.

While CBD is typically given as drops or oil added to food, hemp-based treats can also be used. Giving CBD-infused treats to pets suffering from noise anxiety, however, failed to show a positive outcome.

In many countries, treating pets with CBD is not authorised or approved. In the UK, only a vet can prescribe a human CBD preparation for a pet.

Cannabidiol is considered a complementary medicine and vets advise that it should not be used in place of proven treatments. CBD could also interact with prescribed drugs in ways that arent currently known.

Toxicity reports are rare, and healthy dogs appear to tolerate long-term, daily doses of CBD. However, side-effects such as vomiting, diarrhoea, lethargy and difficulty moving have been recorded in dogs. Side-effects in cats include excess licking and salivation, pacing, vomiting and grimacing. We still dont have good safety and efficacy data, and effective dose rates are unclear.

A significant challenge in being able to identify consistent outcomes in CBD use is the variability in quality, preparations and potency of the active ingredient. CBD can also be provided in edible treats, oils and supplements or as topical creams to be applied to the skin. These all have different uses, making outcome comparisons tricky.

There is also the potential for mislabelling and contamination of CBD products, and production and distribution regulation is poor. This can make it difficult for pet owners to make informed, safe and effective choices for their pets.

While the use of CBD for pets appears to be common, the potential downsides and concerns do need to be considered. How much CBD can be safely administered to our pets for effective use across a range of conditions remains largely unknown.

If you are thinking about using CBD for your pet, always speak to your vet in the first instance they will be able to advise you on the safest and most legally appropriate way to do so.

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Danish dog owners are medicating their pets with unlicensed cannabis products is it safe? - The Conversation

After the 2018 Farm Bill removed most hemp products from the Controlled Substances Act, cannabis-based consumablesproliferated for dogs, cats and other pets. While hemp seed oil, hearts and protein powder are Generally Recognized as Safe (GRAS) by the U.S. Food and Drug Administration, cannabidiol (CBD) remains in regulatory limbo. Likewise, despite the proliferation of CBD products appearing in the pet supplement space, the actual effects of the chemical on dogs and cats havent been thoroughly evaluated under controlled conditions.

To help meet this need for empirical information about CBD in pet supplements, researchers with Colorado State University and Hills Pet Nutrition collaborated in a long-term study of CBDs effects on dogs. After 36 weeks of CBD supplementation, none of the dogs in the study showed serious health problems. Only at the highest dosage did some of the dogs get loose stools.

This study was important to show that dogs are able to tolerate doses generally much higher than what most of these brands are marketing towards, Breonna Kusick, neurology clinical trials manager at Colorado State University told pet food industry. However, it's important to note that these are all very healthy dogs, and the higher doses may not necessarily be as well-tolerated in dogs with any sort of illnesses or on any additional medications. With that said, I think it's important for CBD-based pet supplement brands to continue reviewing new literature to stay on top of their own recommendations. I also think it's helpful for these brands to understand what to watch for (such as signs of liver disease) for pet parent education.

Dog owners who choose to supplement their pets diets with CBD should watch for signs of liver disease, including vomiting, diarrhea, decreased appetite and general fatigue, Kusick said. Yellowing of the eyes and skin can be signs of more advanced liver disease.

Any pet on CBD experiencing any of those signs should be seen by their veterinarian as soon as possible for bloodwork and possibly more advanced diagnostics, she said.

In the study, the researchers assigned 18 healthy adult Beagles to three groups of

six. Each of those groups received 0, 5 or 10 milligrams of CBD per kilogram of body weight every day for 36 weeks.

This study shows that while the doses are well-tolerated, there is a reported adverse event of softer stools and one liver enzyme is consistently elevated, although not enough to be significant, Kusick said. However, that's only on the highest dose of 10mg/kg/day. So, as the paper mentions, that dose should be used with caution, and it probably wouldn't be helpful in an otherwise healthy dog. In terms of the 5mg/kg/day dose, it's difficult to make any sort of conclusion about a positive or negative influence on pet health since no significant adverse events were seen and the dogs' overall health was the same at the end of the study as it was at the beginning.

The study wasnt designed to examine the positive effects of supplements on dogs' health or behavior. Likewise, the dogs were all healthy to begin with, so there were no disease symptoms to be remedied.

There's still a high need for more studies to be conducted looking at CBD's effect on different disease processes, Kusick said.

While this and other studies havent found low doses of CBD to be harmful to dogs, cannabidiol remains restricted to pet supplements, as does the hemp CBD comes from. Interest in the use of hemp in commercial animal feed has accelerated since the passage of the2018 Agricultural Improvement Act (Farm Bill). While the Farm Bill expanded the legal production of hemp in the United States, the use of hemp and hemp by-products in animal feed, including pet food, remains under the jurisdiction of theU.S. Food and Drug Administration(FDA) and state regulatory programs for commercial animal feed.

This year, as negotiations for thenext U.S. Farm Billcommenced, a coalition of 33 hemp industry groups called for the regulation of CBD and other ingredients derived from hemp under the existing frameworks for dietary supplements and food additives as outlined inHR 1629andS 2451.

There's still a bit of a wild west component to CBD as the market is not regulated so it's important to always look for a certificate of analysis when considering any CBD-based products, Kusick said.

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Long-term CBD for dogs caused few health problems - PetfoodIndustry.com

NEW YORK, Feb. 8, 2024 /PRNewswire/ -- TheCBD oil market is to grow by USD 5.36 billion from 2023to 2027 progressing at a CAGR of27.63% during the forecast period.The report offers an up-to-date analysis regarding the current global market scenario, the latest trends and drivers, and the overall market environment. The market is driven by the growing millennial population in key cannabis markets.The growing millennial population in key cannabis markets is a key factor driving the market growth.

Here is an Exclusive report talking about Market scenarios with a historical period (2017-2021)and forecast period (2023-2027).Download a Free Sample Report in minutes!

Millennials demonstrate a distinct consumer behavior in their preference for consuming cannabis products, particularly in the CBD Oil Market. This preference is driven by their inclination towards experimentation with different variants of cannabis(drugs), especially for recreational purposes, compared to older generations.

The CBD oil market covers the following areas:

CBD Oil Market 2023-2027 - Market Dynamics

Major Trend

The growth in the e-commerce industry is amajor trendin the market.Increasing internet and smartphone usage enhances the convenience and adoption of online shopping by CBD Oil Market consumers. Additionally, secure transactions and cash-on-delivery options boost the online sales of cannabis-infused edible products.

Significant Challenge

The adverse effects of CBD oil products are significantchallenges restricting market growth.The legalization of cannabis in any country carries risks, including the potential for overconsumption, which can lead to respiratory problems and health issues. Additionally, legalizing marijuana may lead to passive consumption by older individuals, presenting significant health risks, particularly for those with post-traumatic stress disorder (PTSD) and dystonia.

CBD Oil Market2023-2027: Market Segmentation

The CBD oil market analysis includes end-user (medical, personal use, pharmaceutical, and wellness), product (marijuana-derived CBD oil and hemp-derived CBD oil), and geography (North America, South America, Europe, APAC, and Middle East and Africa)

This report presents a detailed picture of the market by way of study, synthesis, and summation of data from multiple sources through an analysis of key parameters- View a Free Sample Report

Companies Mentioned

Company Offering

Isodiol International Inc. -The key offerings of the company include CBD oil such as RapidCBD hemp oil.

Aurora Cannabis Inc. - The company offers CBD oil such as Aurora CBD drops.

BIOTA Biosciences LLC - The company offers CBD oil such as Biota premium CBD oil.

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Related Reports

The cannabidiol (CBD) skin care marketsize is estimated to grow at a CAGR of 26.74% between 2022 and 2027. The market size is forecast to increase by USD 2,197.99 million.

The Cannabidiol market size is projected to increase by USD 23,023.51 million and the market size is estimated to grow at a CAGR of 16.28% between 2022 and 2027.

ToC:

Executive Summary

Market Landscape

Market Sizing

Historic Market Sizes

Five Forces Analysis

Market Segmentation by End-User

Market Segmentation by Product

Market Segmentation by Geography

Customer Landscape

Geographic Landscape

Drivers,Challenges, &Trends

Company Landscape

Company Analysis

Appendix

About Us Technavio is a leading global technology research and advisory company. Their research and analysis focus on emerging market trends and provide actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions. With over 500 specialized analysts, Technavio's report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavio's comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios.

Contact Technavio Research Jesse Maida Media & Marketing Executive US: +1 844 364 1100 UK: +44 203 893 3200 Email: [emailprotected] Website: http://www.technavio.com

SOURCE Technavio

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CBD Oil Market to grow by USD 5.36 billion from 2022 to 2027; Aurora Cannabis Inc. and BIOTA Biosciences LLC ... - PR Newswire

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Medallion Green CBD Gummies Reviews: Legit Shark Tank CBD Official? - Deccan Herald

Research suggests the cannabinoids in topical CBD creams may be absorbed more efficiently by the body through the skin, rather than passing through digestion, as is the case with orally ingested CBD products.

Although research in the U.S. is ongoing, preliminary studies show that topical CBD cream may be beneficial when it comes to treating chronic pain conditions, such as arthritis. However, additional well-designed human clinical trials are needed, as much of the existing research is based on animal studies or anecdotal results.

One small, placebo-controlled 2020 study in Current Pharmaceutical Biotechnology examined the use of topical CBD in 29 participants with peripheral neuropathy, a chronic pain condition caused by nerve damage. The results showed that the 15 participants using topical CBD oil experienced significantly less pain compared to the 14 participants using the placebo after four weeks .

Another 2018 study with over 300 participants with knee pain from osteoarthritis found a transdermal synthetic CBD gel significantly improved patients worst pain score and physical function averages. These patients were treated with 350 milligrams of CBD gel per day for 12 weeks .

Additionally, some research suggests that the anti-inflammatory properties of CBD cream may help to improve certain skin conditions such as acne and eczema.

CBD itself is safe and well tolerated, and it has no risks of abuse or dependence, according to the World Health Organization.

Additionally, using CBD topically reduces the likelihood of experiencing side effects typically associated with CBD use, such as drowsiness, fatigue and diarrhea, says Dr. Milanes.

Milanes and Fuentes warn that while CBD itself might be safe, there is a chance you might be allergic or sensitive to another ingredient in a CBD topical, which could cause adverse effects. To avoid unpleasant reactions, they suggest reading ingredient lists carefully.

Phan also recommends talking to your doctor before using CBD if youre on any medications especially blood pressure medications because CBD can also lower blood pressure.

Because CBD creams arent regulated by the Food and Drug Administration (FDA) as topical drug products, its difficult to determine their safety and efficacy as a product category. However, the American Academy of Dermatology (AAD) reports that topical CBD products may be effective in treating conditions including acne, psoriasis and eczema with few or no side effects. Ultimately, safety and efficacy depend on the specific CBD cream product and its formulation.

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10 Best CBD Creams Of 2024 Forbes Health - Forbes