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Monthly Archives: September 2023
Targeting Tumors with Photosynthetic Bacteria – Optics & Photonics News
Posted: September 17, 2023 at 11:45 am
Illustration of a colon cancer cell. [Image: Kateryna Kon / Science Photo Library / Getty Images]
The treatment of malignant tumors has long presented a challenge for cancer researchers. Bacteria-based therapiesin which microbes, often souped-up by genetic engineering or nanotechnology, are put to work as on-site cancer killersshow promise for improving upon conventional methods. But these techniques have drawbacks, including the risk of antibiotic resistanceand the need for complicated procedures that could degrade the bacteria.
Now, researchers in Japan have demonstrated a new approach for enhancing purple photosynthetic bacteria, which they say is an ideal strain for effective cancer phototherapy (Nano Today, doi: 10.1016/j.nantod.2023.101966). Their process, which involves simple chemical functionalization, preserves the innate medicinal qualities of the bacteria while enhancing their ability to fight cancer.
The researchers chose the purple photosynthetic bacteria Rhodopseudomonas palustris(RP) as an optimal candidate for cancer treatment because it is spatiotemporally activatable by near-infrared light and shows strong photothermal conversionthe ability to turn laser light energy into heat, in this case to selectively eliminate cancer cells. This is thanks to its bacteriochlorophyll (BChl) light-harvesting nanocomplexes, which are useful for targeted optical cancer therapies.
RP demonstrated excellent properties, such as near-infrared (NIR) fluorescence, photothermal conversion and low cytotoxicity, explainedlead author Eijiro Miyako, Japan Advanced Institute of Science and Technology (JAIST), in a press release accompanying the paper.Itabsorbs NIR light and produces free radicalsa property that can be utilized to kill cancer cells.
The membranes of photosynthetic bacteria were PEGylated, and fluorescent markers and an anti-PD-L1 antibody were attached to enable tumor-targeting and immunological activation. The engineered bacteria demonstrated effective tumor suppression and immunological responses in a mouse model of colon cancer. [Image: Eijiro Miyako] [Enlarge image]
After selecting their preferred bacteria, the researchers looked to improve them through a series of modifications. First, they attached polyethylene glycol (PEG) derivatives, including one called Biocompatible Anchor for Membrane (BAM), to the bacterial cell walls. Known as PEGylation, this process has a number of benefits, including helping the complex evade host immune response and facilitating attachment of other biomolecules. The team then affixed a fluorescent Alexa488-BSA conjugate to the BAM, which allowed it to be tracked with fluorescence microscopy and used for locating tumors.
Finally, the researchers tacked on an immune checkpoint inhibitor antibody known as anti-PD-L1 using the same BAM method. Cancer cells express a protein called Programmed Cell Death Ligand 1 (PD-L1), which suppresses the hosts immune response and allows cancer cells to evade detection and elimination. Anti-PD-L1 antibodies block PD-L1, thus preventing cancer cells from flying under the immune radar and allowing them to be targeted by the hosts immune system.
To examine the efficacy of the various bacterial complexes, the researchers pitted them against colon cancer in mice in a series of experiments. Tests showed that anti-PD-L1BAMRP, BAMRP and RP inhibited tumor growth when injected in mice with colon cancer. However, all the varieties had an especially dramatic anticancer effect when excited with an NIR laser at 0.7 W for 3 minutes.
During the 30-day follow-up period after the experiment, solid tumors disappeared completely in mice that underwent laser irradiation of injected anti-PD-L1BAMRP, BAMRP, or RP. Laser-induced anti-PD-L1BAMRP was the most effective during the primary treatment stage and also cured tumors faster than the others.
Our findingsrevealed that light-driven functional bacteria demonstrated effective optical and immunological functions in the murine model of colon cancer. Moreover, the NIR fluorescence of the engineered bacterial complexes was used to locate tumors, effectively paving the way for future clinical translation, saysMiyako. We believe that this bacterial technology could be available for clinical trials in 10 years and have positive implications for cancer diagnosis and therapy.
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Artificial Photosynthesis Breakthrough Researchers Produce … – SciTechDaily
Posted: at 11:45 am
Researchers have utilized in-cell engineering to produce hybrid solid catalysts for artificial photosynthesis using protein crystals. These catalysts, created through genetically modified bacteria, are highly active, durable, and eco-friendly, paving the way for a novel approach in enzyme immobilization.
Researchers at Tokyo Tech have demonstrated that in-cell engineering is an effective method for creating functional protein crystals with promising catalytic properties. By harnessing genetically altered bacteria as a green synthesis platform, the researchers produced hybrid solid catalysts for artificial photosynthesis. These catalysts exhibit high activity, stability, and durability, highlighting the potential of the proposed innovative approach.
Protein crystals, like regular crystals, are well-ordered molecular structures with diverse properties and a huge potential for customization. They can assemble naturally from materials found within cells, which not only greatly reduces the synthesis costs but also lessens their environmental impact.
Although protein crystals are promising as catalysts because they can host various functional molecules, current techniques only enable the attachment of small molecules and simple proteins. Thus, it is imperative to find ways to produce protein crystals bearing both natural enzymes and synthetic functional molecules to tap their full potential for enzyme immobilization.
Against this backdrop, a team of researchers from Tokyo Institute of Technology (Tokyo Tech) led by Professor Takafumi Ueno has developed an innovative strategy to produce hybrid solid catalysts based on protein crystals. As explained in their paperpublished inNano Letterson 12 July 2023, their approach combines in-cell engineering and a simplein vitroprocess to produce catalysts for artificial photosynthesis.
Graphic explaining the research. Credit: Professor Takafumi Ueno, Tokyo Institute of Technology
The building block of the hybrid catalyst is a protein monomer derived from a virus that infects theBombyx morisilkworm. The researchers introduced the gene that codes for this protein intoEscherichia colibacteria, where the produced monomers formed trimers that, in turn, spontaneously assembled into stable polyhedra crystals (PhCs) by binding to each other through their N-terminal -helix (H1). Additionally, the researchers introduced a modified version of the formate dehydrogenase (FDH) gene from a species of yeast into theE. coligenome. This gene caused the bacteria to produce FDH enzymes with H1 terminals, leading to the formation of hybrid H1-FDH@PhC crystals within the cells.
The team extracted the hybrid crystals out of theE. coli bacteria through sonication and gradient centrifugation and soaked them in a solution containing an artificial photosensitizer called eosin Y (EY). As a result, the protein monomers, which had been genetically modified such that their central channel could host an eosin Y molecule, facilitated the stable binding of EY to the hybrid crystal in large quantities.
Through this ingenious process, the team managed to produce highly active, recyclable, and thermally stable EYH1-FDH@PhC catalysts that can convert carbon dioxide (CO2) into formate (HCOO) upon exposure to light, mimicking photosynthesis. In addition, they maintained 94.4% of their catalytic activity after immobilization compared to that of the free enzyme. The conversion efficiency of the proposed hybrid crystal was an order of magnitude higher than that of previously reported compounds for enzymatic artificial photosynthesis based on FDH, highlights Prof. Ueno. Moreover, the hybrid PhC remained in the solid protein assembly state after enduring bothin vivoandin vitroengineering processes, demonstrating the remarkable crystallizing capacity and strong plasticity of PhCs as encapsulating scaffolds.
Overall, this study showcases the potential of bioengineering in facilitating the synthesis of complex functional materials. The combination ofin vivoandin vitrotechniques for the encapsulation of protein crystals will likely provide an effective and environmentally friendly strategy for research in the areas of nanomaterials and artificial photosynthesis, concludes Prof. Ueno.
And we sure hope that these efforts will lead us to a greener future!
Reference: In-Cell Engineering of Protein Crystals into Hybrid Solid Catalysts for Artificial Photosynthesis by Tiezheng Pan, Basudev Maity, Satoshi Abe, Taiki Morita and Takafumi Ueno, 12 July 2023, Nano Letters. DOI: 10.1021/acs.nanolett.3c02355
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BASF patent on watermelons upheld: European Patent Office rejects … – Bio Eco Actual
Posted: at 11:45 am
The European Patent Office (EPO) has rejected an opposition filed against a BASF (Nunhems) patent on watermelons with bushy growth habit (EP2814316). No Patents on Seeds! filed the opposition because the patent is not inventive and patents on conventionally-bred plant varieties are prohibited.
The bushy growth of the plants was a random occurrence and, according to the patent description, the plants were simply a discovery in a home-garden. Their advantage: less land is needed for cultivation. The EPO granted the patent in 2021 as the patent holder had applied an additional well-established method (for generating triploid plants) to reduce the number of kernels. Clearly, neither the applied method nor the detection of the bushy growth habit is based on an invention.
Christoph Then, coordinator at No Patents on Seeds! the international coalition that filed the opposition: The EPO decision is in direct contradiction to the law and to the basic principles of the patent system. No one can claim an invention if a discovery is combined with well-known methods and the results are not surprising. The prohibitions in regard to patentability of conventional bred plants are severely violated. This decision is setting an extreme precedence in regard to life patents.
Patents can only be granted if the plant characteristics are obtained from genetic engineering
According to European patent law, patents on plant varieties are generally prohibited. Patents can only be granted if the plant characteristics are obtained from genetic engineering.
In Europe, the plant variety protection (PVP) law guarantees that breeders can use all conventionally-bred varieties to breed and market improved varieties. In contrast, patents can be used to hamper or block access to biodiversity needed by all breeders. If such patents are granted, only big companies can survive in the long-term, and they will then decide what is grown and harvested, as well as what food is marketed at which price.
No Patents on Seeds! plans to appeal the EPO decision and is demanding that politicians take their responsibility seriously and finally implement the existing prohibitions in patent law. Patents on conventionally-bred plants and animals have to be stopped. The Austrian government has already decided to amend national patent laws as a first step, other European countries may follow soon.
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Space Industry Is Growing Faster Than Its Workforce, Analysts Say – Slashdot
Posted: at 11:44 am
Analysts are concerned that a lack of skilled labor in the space industry "could impact aerospace's growth in recent years, putting key projects on hold or preventing space startups from gaining traction," reports ExtremeTech. From the report: According to the Space Foundation's annual Space Report, job opportunities within the U.S. space industry have grown 18% over the past five years. Meanwhile, American colleges saw a decline in engineering students across the same period, prompting the industry to wonder whether the workforce could keep up with demand. Indeed, the Space Foundation says only 17% of NASA's workforce is under 35; not only does the agency tend to hire workers who have accumulated a lot of experience, but there aren't as many young professionals under consideration as there could be.
The industry isn't just short on engineers, though. Although STEM degrees requiring an intimate familiarity with astronomy, physics, robotics, computing, mathematics, and other technical topics are certainly one path toward space, the industry relies on workers proficient in a much wider range of skills. Welders, electricians, crane operators, and other blue-collar workers are essential to manufacturing and ground operations. In contrast, marketers, PR representatives, bookkeepers, lawyers, and other office workers keep things running in the background. In fact, as of writing, SpaceX is even hiring a barista.
As Space Foundation CEO Tom Zelibor put it in the nonprofit's Q1 2023 report, the space industry might benefit from informing the public of the benefits of space exploration. These benefits are apparent to some, but others find space exploration nonessential or frivolous. Other people interested in the space industry might be scared off from pursuing it as a career, thanks to its reputation for requiring advanced degrees and mathematical prowess. From the Space Foundation's own educational projects to those run by The Planetary Society and Space for Humanity, public outreach could be the key to bolstering industry engagement. The report notes that the "space economy" has ballooned to $464 billion (up 159% from 2010) and is predicted to reach a $1 trillion valuation by 2030, according to some analysts.
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New ‘Inverse Vaccine’ Shows Potential to Treat MS and Other … – Slashdot
Posted: at 11:44 am
This week saw an announcement from the University of Chicago's Pritzker School of Molecular Engineering. A new type of vaccine "has shown in the lab setting that it can completely reverse autoimmune diseases like multiple sclerosis and type 1 diabetes all without shutting down the rest of the immune system." A typical vaccine teaches the human immune system to recognize a virus or bacteria as an enemy that should be attacked. The new "inverse vaccine" does just the opposite: it removes the immune system's memory of one molecule. While such immune memory erasure would be unwanted for infectious diseases, it can stop autoimmune reactions like those seen in multiple sclerosis, type I diabetes, or rheumatoid arthritis, in which the immune system attacks a person's healthy tissues. The inverse vaccine, described in Nature Biomedical Engineering, takes advantage of how the liver naturally marks molecules from broken-down cells with "do not attack" flags to prevent autoimmune reactions to cells that die by natural processes. Pritzker School of Molecular Engineering researchers coupled an antigen a molecule being attacked by the immune system with a molecule resembling a fragment of an aged cell that the liver would recognize as friend, rather than foe. The team showed how the vaccine could successfully stop the autoimmune reaction associated with a multiple-sclerosis-like disease...
Jeffrey Hubbell [lead author of the new paper] and his colleagues knew that the body has a mechanism for ensuring that immune reactions don't occur in response to every damaged cell in the body a phenomenon known as peripheral immune tolerance, which is carried out in the liver. They discovered in recent years that tagging molecules with a sugar known as N-acetylgalactosamine (pGal) could mimic this process, sending the molecules to the liver where tolerance to them develops. "The idea is that we can attach any molecule we want to pGal and it will teach the immune system to tolerate it," explained Hubbell. "Rather than rev up immunity as with a vaccine, we can tamp it down in a very specific way with an inverse vaccine."
In the new study, the researchers focused on a multiple-sclerosis-like disease in which the immune system attacks myelin, leading to weakness and numbness, loss of vision and, eventually mobility problems and paralysis. The team linked myelin proteins to pGal and tested the effect of the new inverse vaccine. The immune system, they found, stopped attacking myelin, allowing nerves to function correctly again and reversing symptoms of disease in animals. In a series of other experiments, the scientists showed that the same approach worked to minimize other ongoing immune reactions...
Initial phase I safety trials of a glycosylation-modified antigen therapy based on this preclinical work have already been carried out in people with celiac disease, an autoimmune disease that is associated with eating wheat, barley and rye, and phase I safety trials are under way in multiple sclerosis. Those trials are conducted by the pharmaceutical company Anokion SA, which helped fund the new work and which Hubbell cofounded and is a consultant, board member, and equity holder. The Alper Family Foundation also helped fund the research.
"There are no clinically approved inverse vaccines yet, but we're incredibly excited about moving this technology forward," says Hubbell. Thanks to Slashdot reader laughingskeptic for sharing the news.
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Police get new images of area break-in suspect – Southwest Virginia Today
Posted: September 15, 2023 at 10:12 am
From staff reports
Armed with new security camera images, area police are continuing to ask for the publics help in tracking down a suspect in multiple break-ins the most recent on Tuesday evening in Bland County.
According to the Bland County Sheriffs Office, a man carrying a rifle and backpack broke in to a North Scenic Highway residence near South Gap while the property owners were gone.
On Sunday morning, a woman in Bland said a man, who was also armed with a rifle, had a garden pick near her back door before retreating into the woods.
The Sheriffs Office said this week that the man in Tuesdays break-in appears to be the same suspect sought in Wythe and Pulaski counties for similar crimes.
Anyone with information about the man is asked to call 911.
Bland County man convicted of Wythe truck theft
A Bland County man got jail time on Sept. 6 after pleading to four felonies in Wythe County Circuit Court.
Christopher Jennings Sizemore, 44, of Bastian, was convicted of Feb. 17 charges of automobile larceny, grand larceny, conspiracy to commit automobile larceny and conspiracy to commit grand larceny.
According to court records, Sizemore took a bucket truck and tools belonging to D.H. Elliot Co.
As part of a plea agreement, Sizemore was sentenced to serve one year and three months in jail with credit for time served while awaiting trial.
After his release, hell be on supervised probation for three years, during which time hell waive his Fourth Amendment protections. He was also ordered to pay D.H. Elliot Co. $12,350 in restitution and must stay away from the companys property and employees.
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Napolitano: Is the CIA in your underwear? | News, Sports, Jobs – Standard-Examiner
Posted: at 10:12 am
In a year, if a friend asks you if the CIA is in your underwear, youd probably not take the question seriously. Youd be wrong. The CIA is spending millions in tax dollars to get into your underwear next year.
Eleven years ago, when this column asked if the CIA was in your kitchen, folks who read only the title of the column mocked it. Yet, then-CIA Director Gen. David Petraeus gave a talk to CIA analysts that he fully expected to be kept secret. In the talk he revealed that CIA vendors had discovered a means to log on to the computer chips in kitchen microwave ovens and dishwashers. From there, they could listen in real time to the conversations in a kitchen if those chatting were nearby the appliances.
Unfortunately for Petraeus, but fortunately for the Constitution, one of his analysts was so critical of the CIAs disdain for constitutional norms that the analyst recorded a major portion of Petraeuss talk and leaked it to the media. Is the CIA in your kitchen? Yes, not physically, but virtually.
The CIA, notwithstanding a clause in its charter that prohibits it from engaging in surveillance in the United States or from engaging in any law enforcement activities, has a long history of domestic spying without search warrants.
That last phrase without search warrants when used in conjunction with CIA spying is redundant. The CIA does not deal with search warrants. It behaves as if the Fourth Amendment and the First (protecting the freedom of speech and of the press) and Fifth (protecting life, liberty and property), for that matter do not exist or somehow do not pertain to its agents.
Not long ago, I was challenged to a public debate at the Conservative Political Action Conference by the general who was then the head of the National Security Agency, the CIAs domestic surveillance cousin. The topic of the debate was whether domestic warrantless spying is constitutional. I accepted the challenge and aggressively pressed the general on the notorious lack of fidelity that the 17 federal spying agencies have for the Constitution in general, and specifically the Fourth Amendment.
The general gave me two answers, both of which would have flunked a bar examination. First, he argued that the Fourth Amendment only protects against unreasonable surveillance, and his 60,000 domestic spies were behaving reasonably. After the laughter died down, I pointed out that the Supreme Court has held that all searches and seizures all surveillance conducted without search warrants are as a matter of law unreasonable, and thus violative of the amendment.
Then he retreated to a post-9/11 argument crafted by the Department of Justice in the George W. Bush administration. That argument offers that the Fourth Amendment only restrains law enforcement; it does not restrain the intelligence community. I pointed out that this view is defied by both language and history.
The plain language of the amendment has no exceptions to it. Rather, it protects the right of the people to be secure in their persons, houses, papers, and effects.
I then reminded him we were friends, mind you; but I could not let him get away with publicly trashing the document he and I had both sworn to preserve, protect and defend that the Fourth Amendment was written in the aftermath of British intelligence agents breaking down the doors of colonists homes ostensibly looking for compliance with the Stamp Act of 1765 but really looking for subversive materials by folks whom today we call the Founding Fathers.
I present this brief background so as to offer a flavor for the mindset of the feds who spy on us and to address the latest craze among senior level intelligence folks in the Biden administration.
Last week, the Director of National Intelligence she is the nominal head of all 17 federal surveillance agencies revealed to Congress that she had spent $22 million in order to develop cotton fibers that she called smart clothing. The fibers will enable the CIA and other federal spies to record audio, video and geolocation data from your shirt, pants, socks and even your underwear. She billed this as the largest single investment ever made to develop Smart ePants.
Smarty pants how appropriate is that name for federal intrusion? Smarty pants is the jerk who cant stop talking and wont change the subject.
The CIA does not directly develop its ability to connect to your kitchen microwave and dishwasher or your socks and underwear. Rather, it hires outside groups to do so. In the case of smarty pants, 28 American tech firms and laboratories have helped to develop this monstrosity. Most are not household names, but some are like the University of Virginia (which is owned by the state of Virginia), Penn State (which is owned by the state of Pennsylvania) and DuPont (which owns most of the state of Delaware).
You cant make this stuff up. The federal governments appetite for surveillance is quite literally insatiable. And its respect for the individual natural right to be left alone is nonexistent. It traffics in evading and avoiding the Constitution, using absurd and puerile arguments that have never been accepted by the courts, even though every single federal employee has sworn an oath of fidelity to the Constitution as it is generally understood and interpreted.
When the DNI told Congress about this while Congress was on its summer break not a peep was heard from anyone in Congress or from the sleepy White House for whom the DNI works.
Does the government work for us, or do we work for the government? What employee gets to spy on his bosses by putting trick textiles into the bosses underwear and then gets away with it? When will Congress protect our liberties? When will enough of this warrantless spying be enough?
To learn more about Judge Andrew Napolitano, visit https://JudgeNap.com.
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Bulletin: Maryland Juvenile Services Head Says Violence Among … – The Trace
Posted: at 10:12 am
Top Story
After a summer punctuated by high-profile shootings and other crimes involving young people, officials in Maryland are weighing whether the states juvenile justice system should be reformed. Some argue that the system, which has moved away from carceral punishment in recent years, should be overhauled and better hold young people accountable.
But Department of Juvenile Services head Vincent N. Schiraldi says perceptions of a youth crime wave are overblown, pointing to a new report showing that overall youth violence has been declining for more than a decade. [The Baltimore Banner/The Washington Post]
New Mexicos temporary gun carry ban has, justifiably, gotten a lot of attention since Governor Michelle Lujan Grishams administration ordered it last week. The ban which is applicable only on public and state property in Albuquerque and surrounding Bernalillo County is largely unprecedented, and it received immediate pushback from gun rights and gun reform proponents alike.
While there is some limited evidence that such an approach could curtail gun violence, New Mexicos gun carry ban isnt a long-term solution. And the order raises some more pressing questions: Is the ban enforceable? Is it constitutional? And what does the order actually do? The Traces Jennifer Mascia and Chip Brownlee explain.
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Public libraries have always sought to build stronger, more resilient communities. These days, theyre playing an important role in gun violence prevention: The library system in Anne Arundel County, Maryland, for example, offers free gun locks at all of its branches. Thats in addition to an array of programs that foster community well-being, like GED classes and computers on loan initiatives that aim to alleviate social conditions associated with gun violence.
Libraries across the country offer services like these, Chip Brownlee reports in the latest edition of The Trajectory. And theres research showing that, even as they face political and financial challenges, libraries are uniquely equipped to help improve public safety.
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A federal judge tossed out the National Shooting Sports Foundations challenge to Delawares public nuisance law, which enables the states attorney general or a private citizen to sue gun companies for failing to follow laws governing the industrys sales and marketing practices. The judge said it was too soon to rule on the law because it had not yet been used in litigation when NSSF filed its challenge. [Reuters]
Floridas extreme risk protection order law allows police to confiscate weapons from people deemed a threat, but its not an automatic process. Could it have saved 24-year-old Dayana Hurtado, whose boyfriend allegedly shot and killed her two weeks after she told law enforcement her life might be in danger? [Miami New Times]
As the manhunt for Danelo Cavalcante a convicted murderer who escaped from a Pennsylvania prison on August 31 and was recaptured this morning entered its 11th day, private citizen Ryan Davis sat in a Wawa parking lot in Chester County, carrying a firearm and operating a drone that scanned the surrounding area looking for movement. He was one of a handful of amateur sleuths, many of them armed, who took the search for Cavalcante into their own hands much to the displeasure of police. [The Philadelphia Inquirer]
Crime data can be difficult to parse, not in small part because of poor reporting practices and inexact definitions of what constitutes a crime. A recent story about gun violence in Canada that conflated shootings with the crime of discharging firearm with intent provides a cautionary tale. [Jeff Asher]
Federal judges rarely throw out evidence based on Fourth Amendment challenges. But in Memphis, where police waged an intense campaign to get guns and drugs off the streets in recent years, the number of successful Fourth Amendment challenges appears significantly higher than in the rest of the country an indication that the department has a problem with overzealous policing. [The Marshall Project]
The University of Chicagos Community Violence Intervention Leadership Academy officially kicked off this week, welcoming a cohort of community leaders into a six-month program designed to enhance violence interruption initiatives by providing guidance on program management, staff retention, evaluation, and more. [Chicago Sun-Times]
Violence Interruption Programs Are Receiving Millions. This Initiative Wants to Make Sure Theyre Prepared: Chico Tillmon, the director of the University of Chicago Crime Labs new leadership academy, discusses the challenges facing community-based organizations and the tools they need to succeed. (June 2023)
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Tased horseman’s excessive force claims clear bar Rhode Island … – Rhode Island Lawyers Weekly
Posted: at 10:12 am
A man on horseback sufficiently alleged excessive force claims against a Lynchburg police officer who tased a him when he fled the attempted service of a permitted warrant, the Western District of Virginia found.
The officer moved to dismiss for failure to state a claim. But U.S. District Court Judge Norman K. Moon said the mans allegations were plausible and rejected the officers qualified immunity defense for now.
Taking all the allegations as true Plaintiff sufficiently alleges a violation of a clearly established constitutional right, the judge held. However, Defendant [] may raise qualified immunity again at a later stage in the proceedings.
In March 2021, the Lynchburg Police Department notified all units that a permitted warrant for an alleged protective order violation was outstanding for Steve Rucker Jr. A warrant is permitted if an officer is required to serve an individual and release them with a summons.
The notice to officers said Rucker was entering the city on horseback. Upon finding Rucker, an LPD officer activated his unmarked cruisers lights and siren. Rucker refused the officers request to stop. A chase ensued through downtown Lynchburg.
The chase lasted about seven minutes, and Rucker turned down about a dozen streets. A pursuing officer told Rucker that they just had paperwork for him. Another officer tried to tase Rucker. He missed and caused the horse to speed up to about 25 mph.
A few minutes later, LPD Officer Zachary Miller tased Rucker. The horse again sped up, and Rucker fell off after two blocks. While Rucker lay in the street, LPD Officer Michael Johnson Jr. jumped out of a nearby cruiser, but it began drifting toward a retaining wall.
Johnson hopped back into his cruiser, turned it hard right, and stepped on the accelerator. The cruiser rolled over Rucker, causing him multiple injuries that required hospitalization.
Rucker sued Miller and Johnson in the Western District of Virginia for excessive force under 42 U.S.C. 1983, as well as state law claims for gross negligence, willful and wanton misconduct, and battery.
Arguing that Rucker failed to state a claim and that qualified immunity shielded him from liability, Miller moved to dismiss.
Excessive force
All claims that law enforcement officials have used excessive force deadly or not in the course of an arrest, investigatory stop, or other seizure of a free citizen are properly analyzed under the Fourth Amendments objective reasonableness standard, Moon explained.
The court must consider the severity of the crime at issue, whether the suspect poses a threat to the safety of the officers or others, and whether the suspect is resisting arrest or attempting to flee arrest.
A court must also consider that officers must make split second judgements in circumstances that are tense, uncertain, and rapidly evolving about the amount of force that is necessary in a particular situation, the judge added.
Moon said the first factor weighed heavily in Ruckers favor because he was not wanted for any crime when the pursuit began.
The circumstances of the alleged protective order violation were not detailed; nothing established that Rucker committed or was suspected of committing any violent or other serious crime.
The second factor also favored Rucker. Moon noted that the allegations did not indicate Rucker was armed, violent or a threat to officers or the public, nor was there a suggestion that Rucker was riding in a violent or reckless manner.
The officer claimed that riding a horse at night through traffic posed a danger. Moon was not swayed but acknowledged that further facts may support a different conclusion.
The third factor also tipped in Ruckers favor, Moon said.
Plaintiff does not suggest he was resisting arrest, but merely avoiding service of a summons, the judge noted. Plaintiff argues that he was also not fleeing arrest because there was no arrest to begin with. Again, considering the allegations in the light most favorable to Plaintiff, the factors demonstrate a plausible claim of excessive force against Defendant Miller.
Moon then pointed out that, according to the 4th U.S. Circuit Court of Appeals, using a taser is a serious use of force that should only be deployed in dangerous situations.
The Fourth Circuit further held that [t]asers may only be deployed when a police officer is confronted with an exigency that creates an immediate safety risk and that is reasonably likely to be cured by using the taser, the judge wrote.
Based on its analysis, Moon found that Rucker did not pose a safety risk to the officer or the public to warrant use of a taser.
Qualified immunity
Rucker claimed he sufficiently alleged a violation of a clearly established constitutional right. As such, Miller was not entitled to qualified immunity. Rucker also contended that the court should wait to decide on qualified immunity until the record was more developed.
Moon acknowledged that excessive force by police is a clearly established violation of the Fourth Amendment and that use of a taser except in exceptional circumstances is excessive force.
Thus, as Plaintiff has sufficiently alleged an excessive force violation and Defendant is not entitled to qualified immunity at this stage in litigation, Defendant Millers motion to dismiss will be denied as to the excessive force claim, Moon wrote, adding that the officer may raise qualified immunity at a later stage in the proceedings.
Richmond litigator Mark Dix, who represents Rucker, said his client was hospitalized for almost a month and incurred more than $288,000 in medical bills from his injuries.
We are very confident that qualified immunity would not provide any kind of obstacle to us getting to the jury, he told Virginia Lawyers Weekly. The 4th Circuit has been clear as day since 2016 in Armstrong v. Village of Pinehurst that you do not use a taser to enforce compliance.
He pointed out that his brief cites scholarship about qualified immunity being based on factual fiction.
It turns out that this doctrine of qualified immunity was based upon somebody altering the United States Code in the late 1800s or early 1900s, but the 4th Circuit found it was bound to apply stare decisis, Dix explained. At some point, courts are going to have to grapple with the sordid history of how 1983 was altered.
He noted that there are cases about the validity of qualified immunity making their way to the U.S. Supreme Court.
Dix said he has not received a settlement offer from the city. The case now proceeds to discovery.
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The absurdity of fact-checkers | Columnists | leader-call.com – leader-call.com
Posted: at 10:12 am
A couple of years ago, I shared a post on Facebook that mocked misinformation. The photo allegedly showed a 206-year-old Tibetan monk who had just been discovered alive in a mountain cave. The caption said he had been in a meditative state called takatet for years. It continued, Among his things, they found an old scroll that read, Stop believing all the crap you read on Facebook.
Recently, the post popped up as a memory on my Facebook page and I shared it again. This time, though, independent fact-checkers blocked it, writing, Independent fact-checkers say this information has no basis in fact. Well, duh!
Last Friday, the 5th U.S. Circuit Court of Appeals ruled against the Biden administrations suppression of information on social media platforms, including Facebook, YouTube and Twitter, regarding posts related to COVID-19 and allegations of election fraud. The ruling specifically applied to the White House, surgeon general, CDC and FBI.
Before the 5th Circuits hearing, a lower-court judge had ruled that U.S. officials illegally coerced social media platforms into censoring those posts. The 5th Circuit agreed, writing that such coercion violated the First Amendments free speech protections. The panel wrote, The government is not permitted to advance these interests to the extent that it engages in viewpoint suppression.
Initiated in July 2016, Crossfire Hurricane was likely the most egregious example of information-suppression and manipulation. The FBI operation occurred at the end of the Obama administration to smear Donald Trump during the 2016 campaign for president and inaugurate Hillary Clinton as president.
After four years of continual media and Democrat charges of Russian collusion, Special Counsel John Durham was appointed in October 2020 to investigate the origins of Crossfire Hurricane. Durhams final report was released May 15, 2023. It documented the roles played by Hillary Clinton, Barack Obama, James Comey and a host of other top administration officials to smear Trump with a Russian Hoax from the summer of 2016 to the end of his term in 2021.
President Biden didnt miss a beat on Jan. 21, 2021, when he began tearing down all that Trump had accomplished during his four years in office. Of course, as we have seen, Biden and his administration worked hand-in-glove with a complicit media to suppress all information that contradicted the establishments mantra about COVID-19, election interference and, the party favorite, climate change.
What can we expect between now and November 2024? Well see national emergencies that will serve as pretense for suspending First, Second, Third, Fourth, Fifth and 10th amendment rights. As weve seen, the courts have ruled the Biden administration has violated Americans right to freedom of speech. The right to bear arms has been under continual attack. New Mexico Gov. Michelle Lujan Grisham just decreed a temporary gun ban in parts of her state commenting that the Second Amendment is not absolute.
And what about our protection from illegal government search and seizure (Fourth Amendment)? Or, our Fifth Amendment right to due process? Ask Jan. 6 prisoners about their rights to a speedy trial as well as excess bail or fines and cruel and unusual punishment (Eighth Amendment).
The Bill of Rights protects Americans only as long as the government respects and abides by its constitutional limitations. Its absurd to give fact-checkers positions of adjudication.
Daniel L. Gardner is a columnist who lives in Starkville. Cntact him at PJandMe2@gmail.com.
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