Daily Archives: October 8, 2022

From Neanderthal genome to Nobel prize: meet geneticist Svante Pbo – Nature.com

Posted: October 8, 2022 at 3:56 pm

  1. From Neanderthal genome to Nobel prize: meet geneticist Svante Pbo  Nature.com
  2. Svante Pbo Awarded Nobel For Examining The Ancient Human Genome  Science Friday
  3. Genome Of Ancient Humans Is The Winning Field Of 2022's Nobel Prize in Medicine  IFLScience
  4. Nobel awarded to Swedish scientist who deciphered the Neanderthal genome  The Washington Post
  5. Nobel Prize Awarded to Scientist Who Sequenced Neanderthal Genome  The New York Times
  6. View Full Coverage on Google News

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From Neanderthal genome to Nobel prize: meet geneticist Svante Pbo - Nature.com

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Revealing the genome organization of the earliest common ancestor of all mammals – Tech Explorist

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From a platypus to a blue whale, all living mammals today are descendants of a single ancestor that existed around 180 million years ago. However, less is known about this animal.

Now, an international team has computationally reconstructed the organization of its genome. The reconstructed ancestral genome could help in understanding mammals Evolution and conservation of modern animals. The reconstructed ancestral genome could help in understanding mammals Evolution and conservation of modern animals.

The earliest mammal ancestor likely looked like the fossil animal Morganucodon, which lived about 200 million years ago.

Harris Lewin, distinguished professor of evolution and ecology at the University of California, Davis, said,Our results have important implications for understanding the evolution of mammals and conservation efforts.

Scientists drew on high-quality genome sequences from 32 living species representing 23 of the 26 known orders of mammals. They included chimpanzees, humans, wombats, domestic cattle, rhinos, bats, pangolins, and manatees. The genomes of the chicken and Chinese alligators were also analyzed as comparison samples. The Earth BioGenome Project and other extensive biodiversity genome sequencing initiatives produce some of these genomes. The Working Group for the Earth BioGenome Project is presided over by Lewin.

Joana Damas, the first author of the study and a postdoctoral scientist at the UC Davis Genome Center, said,The reconstruction shows that the mammal ancestor had 19 autosomal chromosomes, which control the inheritance of an organisms characteristics outside of those controlled by sex-linked chromosomes, (these are paired in most cells, making 38 in total) plus two sex chromosomes. The team identified 1,215 blocks of genes that consistently occur on the same chromosome in the same order across all 32 genomes. These building blocks of all mammal genomes contain genes critical to developing a normal embryo.

The scientists found nine whole chromosomes or chromosome fragments in the mammal ancestor whose gene arrangement is similar to modern birds chromosomes.

Lewin said,This remarkable finding shows the evolutionary stability of the order and orientation of genes on chromosomes over an extended evolutionary timeframe of more than 320 million years. In contrast, regions between these conserved blocks contained more repetitive sequences and were more prone to breakages, rearrangements, and sequence duplications, which are major drivers of genome evolution.

Professor William Murphy, Texas A&M University, who was not an author of the paper, said,Ancestral genome reconstructions are critical to interpreting where and why selective pressures vary across genomes. This study establishes a clear relationship between chromatin architecture, gene regulation, and linkage conservation. This provides the foundation for assessing the role of natural selection in chromosome evolution across the mammalian tree of life.

Scientists could follow the ancestral chromosomes forward in time from the common ancestor. Scientists, in time, could trace ancestral chromosomes from the same ancestor. They discovered that there were variations in chromosomal rearrangement rates among mammal lineages. For instance, when an asteroid strike 66 million years ago wiped out the dinosaurs and gave rise to mammals, the rearrangement process in the ruminant lineagewhich gave rise to contemporary cattle, sheep, and deeraccelerated.

Co-author Dr. Camilla Mazzoni said,The results will help to understand the genetics behind adaptations that have allowed mammals to flourish on a changing planet over the last 180 million years.

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Mitochondrial DNA Is Working Its Way Into the Human Genome – Technology Networks

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Scientists at the University of Cambridge and Queen Mary University of London have discovered that mitochondrial DNA can make its way into nuclear DNA. The study is published in Nature.

Mitochondria are often referred to as the powerhouses or batteries of a cell, due to their role in energy conversion, among other critical molecular processes. They possess their own circular DNA called mitochondrial DNA (mtDNA), which is particularly interesting to scientists due to its distinct properties, such as a high rate of polymorphisms and mutations.

Another unique feature of mtDNA is that it is inherited by offspring via the maternal line i.e., the DNA is passed down from our mother, not our father. This characteristic of mitochondria was widely accepted until a 2018 paper from researchers at the Cincinnati Childrens Hospital Medical Center proposed it had found evidence of paternal transmission.

Mitochondria are a type of organelle that are found in the cytoplasm of almost all eukaryotic cells. They convert chemical energy obtained via nutrients to a form of energy that can be used by the cell, via a process known as oxidative phosphorylation. In the mitochondria, a reaction called the Krebs cycle produces the chemical NADH, which is then used by enzymes to create adenosine triphosphate (ATP). Dysfunction of the mitochondria resulting in their inefficiency is a hallmark of aging and many chronic diseases.

In 2020, a team led by Professor Patrick Chinnery from the Medical Research Council Mitochondrial Biology Unit utilized data from Genomics Englands 100,000 Genomes Project to study DNA from 11,000 families to explore these claims and hunt for further evidence.

What is the 100,000 Genomes Project?

The 100,000 Genomes Project is a British initiative to sequence 100,000 genomes with the aim of understanding the role our genes play in health and disease.

Essentially, they did discover mtDNA in the nuclear DNA of some children, which they call nuclear-mitochondrial segments (NUMTs). However, these inserts were not present in the parents DNA, meaning they could not have been inherited via the paternal line. Chinnery and colleagues proposed that the earlier work in 2018 had likely discovered these inserts but had reached an incorrect conclusion regarding their origin. We conclude that rare cryptic mega-NUMTs can resemble paternal mtDNA heteroplasmy, but find no evidence of paternal transmission of mtDNA in humans, they wrote in the publication.

The new study published in Nature is an expansion of the 2020 work, adopting an even larger sample size 66,083 people, including 12,509 people with cancer to explore the NUMTs landscape.

They discovered that new inserts of mtDNA into nuclear DNA are happening frequently and offer new insights into the evolution of the human genome. Billions of years ago, a primitive animal cell took in a bacterium that became what we now call mitochondria. These supply energy to the cell to allow it to function normally, while removing oxygen, which is toxic at high levels. Over time, bits of these primitive mitochondria have passed into the cell nucleus, allowing their genomes to talk to each other, Chinnery said. This was all thought to have happened a very long time ago, mostly before we had even formed as a species, but what we've discovered is that thats not true. We can see this happening right now, with bits of our mitochondrial genetic code transferring into the nuclear genome in a measurable way.

The scientists estimate that this DNA transfer occurs once in every 4,000 births. The molecular mechanisms that enable this transfer are not yet clear, but Chinnery hypothesizes that the process occurs within the egg cells of the mother.

Fifty eight percent of the mtDNA insertions were found to occur in protein-coding genome regions. Thus, the transfer of mtDNA will inevitably increase the size of the genome. However, the team found an inverse correlation between NUMT size and the frequency of its occurrence, which they suggest points towards a selective process counter-balancing NUMT insertion, maintaining genome size and removing NUMTs that influence gene expression.

When analyzing the DNA samples from cancer patients, the researchers found a high distribution of NUMTs, arising in around 1 in 1,000 cancers, which they believe reflects genomic instability. In some cases, the insertion of mtDNA contributes to the development of cancer. Our nuclear genetic code is breaking and being repaired all the time, said Chinnery. Mitochondrial DNA appears to act almost like a band-aid, a sticking plaster to help the nuclear genetic code repair itself. And sometimes this works, but on rare occasions if might make things worse or even trigger the development of tumors.

Chinnery and colleagues also questioned whether mtNDA can absorb elements of nuclear DNA, but there was no evidence that this occurs. They attribute this to the large number of mtDNA copies that exist versus the number of copies of nuclear DNA theres a far greater chance that mtDNA will be broken and pass into the nucleus than there is for the reverse to occur. In addition, mtDNA is neatly packaged within two membranes that are not porous, so it would be a challenge for nuclear DNA to work its way in. However, holes in the membrane that protects nuclear DNA can occur, so mtDNA has an easier passageway.

Reference: Wei W, Schon KR, Elgar G, et al. Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes. Nature. 2022. doi:10.1038/s41586-022-05288-7.

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Animated Map: Where to Find Water on Mars – Visual Capitalist

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Explainer: The Different Types of Volcanoes on Earth

Even if you dont live near a volcano, youve been impacted by their activity.

Its estimated that more than 80% of our planets surface has been shaped by volcanic activity. Theyve helped create our mountain ranges, plains, and plateaus, and have even helped fertilize the land that we now use to grow crops.

These critical mounds come in many shapes and sizes. This graphic by Giulia De Amicis provides a brief introduction to volcanoes, explaining their different types of shapes and eruptions.

A volcano starts to form when molten rock rises from a crack in the Earths surface, which often emerge along tectonic plate boundaries.

Magma rises to the Earths surface because its lighter than rock. When it surfaces or erupts, its referred to as lava.

There are various types of volcanic eruptions, depending on the lavas temperature, thickness, and composition. Generally speaking, high gas content and high viscosity lead to explosive eruptions, while low viscosity and gas content lead to an effusive, or steadily flowing, eruption.

Volcanoes vary in size and structure, depending on how theyre formed. Most volcanoes types fall into four main groups:

Shield volcanoes are built slowly, from low-viscosity lava that spreads far and quick. The lava eventually dries to form a thin, wide sheet, and after repeated eruptions, a mount starts to form.

From the top, these types of volcanoes look like a shield, hence the name. While these volcanoes take a while to form, they arent necessarily low. In fact, the worlds tallest active volcano, Mauna Kea in Hawaii, is a shield volcano.

Also known as composite volcanoes, stratovolcanoes are built relatively fast, at least compared to shield volcanoes. This is because, in between lava eruptions, composite volcanoes emit ash and rock, which helps add structure to the mound rather quickly.

Some well-known composite volcanoes are Mount Fuji in Japan, Mount St. Helens in Washington, and Mount Cotopaxi in Ecuador.

Opposite to shield volcanoes, volcanic domes are formed when lava is highly-viscous. Because the thick lava cant travel very far, it starts to pool around the volcanos vent.

This can sometimes create a pressure build-up, meaning dome volcanoes are prone to explosive eruptions.

These types of volcanoes typically dont release lava. Rather, their eruptions typically emit volcanic ash and rocks, known as pyroclastic products.

Cinder cones are characterized by a bowl-shaped crater at the top, and usually dont exceed 400 m (1,312 ft) in height.

Volcanoes have a number of ecological benefits. Once broken down, volcanic materials create exceptionally fertile soil, which can help build prospering new habitats for animals and plants.

Volcanic eruptions can also help cool our climate. When a volcano explodes, ash and sulfur gas from the eruption combine with water droplets and get trapped in the atmosphere for years. This has a cooling effect which is extremely beneficial to us, especially given our current global warming situation.

Dr. Tracy Gregg, associate professor for the University at Buffalos geology department, told Accuweather that volcanoes have actually helped to keep the world about 2 to 3 degrees cooler than it otherwise may be.

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SEC and Crypto: Is Cryptocurrency A Security? – Forbes

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Editorial Note: We earn a commission from partner links on Forbes Advisor. Commissions do not affect our editors' opinions or evaluations.

The Securities and Exchange Commission (SEC) and other U.S. market regulators are getting serious about reigning in the crypto market.

But there is one big unsettled question central to their goals: Is cryptocurrency a security?

The latter half of the crypto portmanteau belies the dilemma: currency, a deliberate choice by the movements founders, underscoring their ambition to supplant fiat currencies as both a store of value and a means of exchange.

Its fair to say that since Bitcoin (BTC) launched in January 2009, crypto has become the Wild West of financial markets. In the past, its decentralized nature kept it from the prying eyes of governments and other regulatory bodies.

Cryptos lack of oversight is the very thing thats so compelling for many enthusiasts. But with few regulations in place, the doors are wide open to nefarious actors who prey on naive investors.

The May crash of stablecoin TerraUSD wiped out more than $600 billion in value and caused a rash of insolvenciesnot to mention deepening the crypto winter. The Biden administration responded by outlining a framework for crypto development that included nods in the direction of crypto regulation.

Lets look at the state of play in crypto regulationand see if we get clarity on whether or not crypto is a security.

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SEC Chair Gary Gensler is on record voicing his displeasure with the current state of crypto regulation

Gensler famously said in June that crypto exchanges that dont cooperate with the SEC are operating outside of the law and may be at risk of enforcement action.

At the heart of Genslers pitch for making the SEC the sheriff of crypto is the argument that cryptocurrencies are securities.

But what are securities? The Securities Act of 1933 and the Securities Exchange Act of 1934 lay out the definition of a security in painful detail. But a more helpful guide can be found in the Howey Test.

The Howey Test comes from a 1946 Supreme Court ruling in the SEC v. W.J. Howey Co., which has been reaffirmed in the courts several times. Under the Howey Test, a transaction is considered to be a security if it meets the following four criteria:

Promoters are marketing and the investing public is buying most of these tokens, touting or anticipating profits based on the efforts of others, Gensler said in a Sept. 8 statement.

In a recent appearance on CNBC, he reiterated his case on crypto. The law is clear. I believe based on the facts and circumstances most of these tokens are securities, he said.

And that means those cryptos must be registered with the SEC under federal laws for securities.

The SEC announced in May that it was nearly doubling its Crypto Assets and Cyber Unit in May. Since then, the SEC, Commodity Futures Trading Commission (CFTC) and Department of Justice (DOJ) have become more active with crypto enforcement. Take a look at some of the laundry list of charges:

Bloomberg reported that the SEC was investigating popular crypto exchange Coinbase (COIN) for allowing users to trade unregistered securities. The SEC also filed an insider trading complaint against a former Coinbase product manager and identified nine cryptocurrencies as securities, and Coinbase insists it doesnt list securities.

Two additional cases have been particularly high-profile in the recent regulatory crypto enforcement actions.

In early October, reality TV star and social media influencer Kim Kardashian agreed to pay a $1.2 million settlement to the SEC tied to charges that she failed to disclose compensation she received for promoting crypto asset EthereumMax on Instagram in June 2021. The SEC fine was over four times more than what she made from the promotion.

Based on the penalty doled out to Kardashian, the SEC might be more interested in the visibility of its crypto crackdowns.

The other major ongoing cryptocurrency regulatory battle is in the courtroom between the SEC and Ripple (XRP) over the sale of its cryptocurrency XRP.

The SEC has brought charges against Ripple, alleging that the companys sales of XRP are illegal securities offerings and that they raised over $1.3 billion through an unregistered, ongoing digital asset securities offering.

Ripple counters the accusation, claiming XRP is a virtual currency, not an investment contract, and therefore not subject to SEC securities laws.

Gordon Allott, CEO of BroadPeak Partners, says the Ripple case should be settled soon and taking on the SEC is an uphill battle. What you do with your crypto can turn it into a security. If you use crypto issuance to fund your operations, it will get the SECs attention.

Attorney William Powers, a partner at Nossaman, said that the Stop Trading on Congressional Knowledge Act of 2012, otherwise known as the 2012 STOCK Act, could provide crypto investors with insight into where Congress stands on the issue.

The 2012 STOCK Act requires all members of Congress to publicly disclose transactions of stocks, bonds, commodities futures, and other forms of securities within 45 days on their websites.

The U.S. House and U.S. Senate ethics guidance explicitly calls for members of Congress to disclose cryptocurrency transactions, seemingly implying that they are classified under the STOCK Act as other forms of securities.

Several members of Congress have subsequently disclosed their crypto trades.

These disclosures demonstrate that there appears to be consensus that cryptocurrencies are considered a type of security covered under the STOCK Act, at least when it comes to trading by members of Congress, Powers said.

Currently, U.S. crypto regulations future remains in the air as regulators continue investigating the market and determining the best path forward.

The U.S. Treasury Dept. is expected to complete an illicit finance risk assessment on decentralized finance (DeFi) and non-fungible tokens (NFTs) in early 2023. Meanwhile, Gensler has asked SEC staff to fine-tune compliance for crypto security tokens.

But more regulations may not necessarily be bad for crypto investors, some experts say.

Having cryptocurrency regulations in place would mean that projects, exchanges, and all cryptocurrency-related businesses are held to a higher standard and as such, are beneficial to investors. Additionally, it protects investors interest, allowing for legal recourse against crypto scams and projects that breach these regulations, says Bobby Ong, co-founder and chief operating officer of CoinGecko.

But Jeremy Wagner, financial analyst at Trading Pedia, says crypto regulation will also cost crypto enthusiasts. More regulation could also lead to more restrictions on how cryptocurrencies can be bought, sold, and used. Additionally, more regulations could make it more difficult for innovative new projects to launch in the cryptocurrency space.

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Why Now? Isn’t It Too Late To Make Money With Cryptocurrency? – FinSMEs

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With 2022 being a rough year for Bitcoin and cryptocurrency in general, many may be looking elsewhere to invest their money.

However, those who have been tracking the crypto market for more than a few years are starting to see familiar patterns re-emerge, and there are increasing rumblings of the cycle repeating. If these people are correct, cryptocurrency may be repeating a cycle of all-time highs being followed by a sell-off and crypto-winter where prices and interest in cryptocurrency is relatively low. This is often followed by a rebound and new all-time highs being reached. So, if youre thinking about investing in crypto, you may not be alone.

Any good investor worth their salt will tell you that before you jump into any investment, you should explore all the downsides and potential risks as well as the upsides. So, with that in mind, lets take a look at some of the biggest issues you need to be aware of when investing in crypto.

The Lack of Regulation

Cryptocurrency is still a largely unregulated market, which can be both good and bad. On the one hand, it allows for more freedom and flexibility when it comes to investing. On the other hand, it also means that there are fewer protections in place if things go wrong. While the US government has begun to take steps to regulate the crypto market, it is still very much in its infancy. This lack of regulation also means that there are no rules or standards when it comes to things like disclosures, insider trading, and other potential issues. As an investor, you need to be aware of these risks and do your own due diligence before investing in any cryptocurrency.

Manipulation by whales

The term whale is used to describe a large holder of a particular cryptocurrency. These whales can often manipulate the market by selling or buying large amounts of a particular coin. This can often lead to price swings that can hurt smaller investors, while the whales take advantage of their pump and dump to reap profits. Its debated if and how often this occurs, but its something to be aware of nonetheless.

Exchanges getting hacked

Another big issue in the crypto world exchanges getting hacked. This can lead to a loss of funds for investors, as well as a loss of confidence in the market. Some of the biggest hacks in recent years have been on exchanges like Mt. Gox, Bitfinex, and Coincheck. While these hacks are often newsworthy, they are also relatively rare. However, they do highlight the need for investors to be aware of the risks involved in storing their coins on an exchange. Many experts recommend only keeping the amount you need on an exchange to trade, and storing the rest in an offline cold storage wallet.

The Potential for Fraud

Another big issue with investing in cryptocurrency is the potential for fraud. This is especially true when it comes to initial coin offerings (ICOs). An ICO is when a company raises funds by selling crypto tokens to investors. These tokens can be used to access the companys products or services, or they may just be a way for the company to raise money. Either way, there have been a number of cases where companies have raised millions of dollars through an ICO only to then disappear with the funds. As an investor, you need to be very careful when considering investing in any ICO. Make sure you do your research and only invest in projects that you believe have a solid chance of success.

The Volatile Nature of the Market

Cryptocurrencies are notoriously volatile, which can make them a risky investment. Prices can swing wildly up and down, and this volatility can be exacerbated by news events or even rumors. This makes it very important for investors to have a solid understanding of the market before investing any money. Its also important to remember that cryptocurrencies are still a relatively new asset class, so they may be more volatile than other investments like stocks or bonds.

Complexity and lack of knowledge or understanding about Crypto Assets by the general public

The majority of people are still not familiar or comfortable with the concept of digital currencies which makes it difficult for them to invest in it. Many people still do not understand how these digital assets work and the potential benefits they offer. This lack of understanding can lead to a lot of people being hesitant to invest in crypto. While some may argue that this will change over time, or that the average investor doesnt need to understand the technology behind crypto to invest, it is still an issue that needs to be considered.

Growing Toll on the Environment

The process of mining for cryptocurrencies requires a lot of energy. This is because the computers that are used to mine need to be constantly running, which uses a lot of electricity. This has led to some concerns about the environmental impact of crypto mining. While there are ways to offset the impact, it is still something that investors need to be aware of. Some estimates suggest that the daily energy expenditure of bitcoin is equal to the entire country of Ireland.

What Are The Best Ways To Mitigate The Risks And Invest In Cryptocurrency Safely?

Despite the risks involved in investing in cryptocurrency, there are still many people who are eager to get involved in the market. If youre considering investing in crypto, there are a few ways you can mitigate the risks:

Do your research

This one is pretty obvious, but its worth repeating. Before investing in any cryptocurrency, make sure you do your research. This means reading up on the history of the project, the team behind it, and the community that supports it. Its also important to understand the technology behind the project and what problem it is solving. The more you know about a project, the better equipped you will be to make an informed investment decision.

Diversify your portfolio

Dont put all your eggs in one basket. When investing in crypto, its important to diversify your portfolio. This means investing in a variety of different projects. This will help to mitigate the risks associated with any one particular project.

Invest only what you can afford to lose

Cryptocurrencies are a risky investment, so its important to only invest what you can afford to lose. This way, if the market takes a turn for the worse, you wont be left bankrupt.

Consider Cryptocurrency IRAs

If youre looking for a way to invest in crypto without putting all your money at risk, you may want to consider investing in a cryptocurrency IRA or 401k. These are retirement accounts that allow you to invest in crypto without having to worry about taxes. They also insulate you from some of the volatility associated with the market.

These are just a few of the biggest issues to consider before investing in cryptocurrency. While the market is full of potential, its important to remember that there are still risks involved. By doing your research and investing only what you can afford to lose, you can help to mitigate some of these risks.

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The Next Big Cryptocurrency Altcoins to Buy in 2022: Shiba Inu, Big Eyes Coin, And Stellar | Bitcoinist.com – Bitcoinist

Posted: at 3:55 pm

Cryptocurrency prices have consistently climbed over the last several years due to how simple and secure blockchain technology is. The market is currently focused on the daily introduction of a new cryptocurrency, as well as appealing features such as trading, NFTs, and so on.

When it comes to cryptocurrency investing, the many blockchain advancements allow investors to make educated choices that are in their best interests. This article focuses on various prominent coins, including Big Eyes Coin (BIG), Shiba Inu (SHIB), and Stellar (XLM).

Shiba Inu (SHIB), sometimes known as the Dogecoin killer, is a famous meme coin. Shiba Inu is one of the cryptocurrencies with a high concentration of whales, or exceptionally large cryptocurrency holders, who are likely to impact the cryptocurrencys recent resurgence substantially.

According to recent cryptocurrency news, Shiba Inu (SHIB), a competitor to Dogecoin, jumped from seventh to second place due to Ethereum whales raising their holdings by more than 580%. This coin, like many others, is not based on cash flows or assets.

Most of the apparent value of meme coins like Shiba Inu (SHIB) is based on speculation and ongoing hype. Not surprisingly, when the Shiba Inu (SHIB) excitement faded in the face of negative market conditions, Shiba Inu (SHIB) token values plummeted, now trading at 87% of their ATH.

SHIB is a meme currency becoming increasingly popular owing to its versatility. It can be used as a value store and a means of payment and aspires to join the NFT market. It is only two years old, but it has the endorsements of influential figures. Musk and Buterin have shown their admiration for SHIB, which helped spread the word about the coin.

There are various reasons why investing in SHIB may be a wise decision. For starters, SHIB has a formidable community behind it, which is critical for any cryptocurrencys long-term development.

Stellar (XLM), a blockchain-based payment network, allows for the digital representation of all types of money, including cryptocurrency and fiat. As a result, the exchange is very broad, and respected financial institutions prefer it. Stellar (XLM) prices may rise before the end of the year.

Stellar (XLM) essentially allows large investors, corporations, and institutions to move funds around with less trouble and at reduced transaction costs. Stellar (XLM) primarily enables smart contracts and allows users to send multiple currencies to other users via different currencies if they own Lumens. Stellar (XLM) does not, like Bitcoin (BTC), allow mining solely on proof of work.

When the Stellar (XLM) network initially became active in 2014, 100 billion Lumens were generated, with annual inflation of 1%. Nonetheless, the community later agreed to reduce the overall amount of Lumens to roughly 50 billion while abandoning the decision to inflate. As a result, half of the 50 billion Lumens are in circulation, with the other half being utilized by the Stellar Development Foundation to sustain the Stellar (XLM) ecosystem.

Stellar (XLM) is one of the most effective altcoin projects available and will play an important role in developing digital money. According to analysts, the value of Stellar (XLM) could rise to $10 per XLM, a significant increase from the present cost.

Big Eyes Coin (BIG) is now making headlines and drawing a lot of interest in its presale period, especially as it has already raised a whopping 3.791 million dollars. This meme coins whitepaper is evidence that it has been paying close attention to the trajectory of the current green investment trends.

This meme coin is committed to giving 5% of all its coins to organizations that help the preservation of our oceans.

Big Eyes Coins (BIG) charitable donation is in line with the Ethereum (ETH) networks recent switch to Proof-of-Stake (PoS). This upgrade significantly lowered the energy required to transfer or mine cryptocurrency (a huge enhancement to the old proof-of-work system).

Instead, individuals in this PoS blockchain network must opt-in as stake validators, enhancing sustainability, a sense of community ownership, and an incentive to join.

Big Eyes Coin (BIG) is now in a good position to attract new potential investors who may have yet to consider trading in cryptocurrencies before this update. Big Eyes Coin (BIG) is waving a green flag to a new audience eager to embrace a community that upholds sustainable values and is dedicated to rescuing the planet. Dont miss out; here is your opportunity potentially make a lot of money!

For More Information on Big Eyes Coin (BIG), visit the links below:

Presale: https://buy.bigeyes.space/Website: https://bigeyes.space/Telegram: https://t.me/BIGEYESOFFICIAL

Disclaimer:This is a paid release. The statements, views and opinions expressed in this column are solely those of the content provider and do not necessarily represent those of Bitcoinist. Bitcoinist does not guarantee the accuracy or timeliness of information available in such content. Do your research and invest at your own risk.

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The Next Big Cryptocurrency Altcoins to Buy in 2022: Shiba Inu, Big Eyes Coin, And Stellar | Bitcoinist.com - Bitcoinist

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Russian Cryptocurrency Banned by the EU – PaymentsJournal

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Many of Russias largest banks have been denied access to the SWIFT network, save for certain energy-related payment activities.There have also been a number of other restrictions placed on Russias ability to move funds around by key members of the G20. In response, Russia legalized cross-border payments with cryptocurrencies.

According to a recent article at Cointelegraph, European Union (EU) regulators have pushed back by completely banning members from receiving cryptocurrency payments from Russia.

The EU and United States have been very active in the Russia sanctions area, given the ongoing conflict with Ukraine and subsequent steps taken by Russia to annex regions of Ukraine. We commented earlier in PaymentsJournal on some of the payments workarounds being utilized by Russians, including the use of CBDCs with China. I expect that the real impact of the sanctions has not been felt yet, and that the brunt of the sanctions will be felt by the Russian people.

Overview bySteve Murphy, Director, Commercial and Enterprise Payments Advisory Service at Mercator Advisory Group.

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Cryptocurrency In A Declining Market: What Lawyers Need To Know About Bankruptcy, Regulation, And Other Trends – Above the Law

Posted: at 3:55 pm

Like any other investment, cryptocurrency can be exciting and rewarding when the market is hot and when it cools down, investors, funds, and the lawyers who advise them can face tricky questions.

As noted in a recent Practising Law Institute Briefing, Cryptocurrency and Bankruptcy: What Lawyers Need to Know Now That Crypto Winter Is Here, crypto is not immune to the effects of a declining market nor to bankruptcy and its related laws.

During the information-packed One-Hour Briefing, presenter Noah Schottenstein, of DLA Piper, walks attendees through the basics of the crypto finance market, defining its unique features as compared to traditional finance. He goes on to explore novel legal issues that bankruptcy courts are only beginning to face.

As explained by Schottenstein, the crypto winter that began earlier this year was associated with the crash of the Terra/Luna cryptocurrencies. The dramatic dip in the crypto market ultimately saw high-profile bankruptcy filings, including the Three Arrows Capital hedge fund and the retail-focused crypto platforms Voyager and Celsius.

The Briefing continues with discussion of topics such as the application of avoidance actions to cryptocurrency transactions, the types of claims and protections retail depositors and other counterparties may hold in bankruptcy proceedings, and the overlay between regulatory structures and bankruptcy law.

In-house counsel, outside attorneys, and compliance, finance, and other allied professionals interested in the structure of cryptocurrency finance markets and bankruptcy law can get up to date with this program and learn why expectations surrounding the impact of bankruptcy may be upended in this evolving landscape.

Crypto and securities regulation

The bankruptcy program comes at a time when the intersection of regulations and crypto is an increasingly hot topic. At The SEC Speaks in 2022, presented by PLI with the SEC in Washington, D.C. on September 8 and 9, a main topic was crypto, crypto, crypto, said Kurt Wolfe, co-host of PLIs inSecurities podcast, in an episode about the conference. Every single panel that I attended talked about crypto, even some of the ones you wouldnt think of, like trading and markets, he said.

Wolfe and co-host Chris Ekimoff discussed the significance of Chairman Genslers opening remarks for The SEC Speaks, titled Kennedy and Crypto. In his speech, the Chairman asserted, Nothing about the crypto markets is incompatible with the securities laws. Investor protection is just as relevant, regardless of underlying technologies.

Interested in learning more?

PLI offers a wealth of resources on cryptocurrency.

If youd like to brush up on the basics, check out the one-day program Think Like a Lawyer, Talk Like a Geek 2022: Get Fluent in Technology, taking place via live webcast and in person on October 14. This unique program is designed to give lawyers the necessary background to become more knowledgeable advocates in technology-related matters and understand the emerging trends in this field, including blockchain, cryptocurrencies, and NFTs.

For those interested in diving into the growing crypto trend of DAOs, or decentralized autonomous organizations, PLI will offer Decentralized Automated Organizations (DAOs): Practical Applications and Legal Framework. Register for the November 16 One-Hour Briefing to learn how DAOs have the potential to disrupt the traditional economic system as they become active investors and lenders, while raising significant issues of securities, tax, and corporate law.

See additional crypto-related content on PLIs website.

Practising Law Institute is a nonprofit learning organization dedicated to keeping attorneys and other professionals at the forefront of knowledge and expertise. PLI is chartered by the Regents of the University of the State of New York and was founded in 1933 by Harold P. Seligson. The organization provides the highest quality, accredited, continuing legal and professional education programs in a variety of formats which are delivered by more than 4,000 volunteer faculty including prominent lawyers, judges, investment bankers, accountants, corporate counsel, and U.S. and international government regulators. PLI publishes a comprehensive library of Treatises, Course Handbooks, Answer Books and Journals also available through the PLI PLUS online platform. The essence of PLIs mission is its commitment to the pro bono community. View PLIs upcoming programs here.

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Cryptocurrency In A Declining Market: What Lawyers Need To Know About Bankruptcy, Regulation, And Other Trends - Above the Law

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Cryptocurrency Price Today 8 Oct: Altcoins Tank As Inflation Soars – CoinGape

Posted: at 3:54 pm

Cryptocurrency Price Today 8th Oct:- The crypto market is down once again as the macroeconomic outlook keeps getting worse. Bitcoin fell below the $20k mark once again and is currently trading at $19,481. It fell close to 2.42% in the last 24 hours.

Altcoins continue to face the major brunt of the sluggishness in the crypto market. Ethereum fell by 2.62% in the last 24 hours and is currently trading at $1327.

Binance Coin or BNB was one of the biggest losers of the crypto market. After facing a major hack with an attempted steal of $600 million, BNB fell by 1.42% in the last 24 hours. It is currently trading at $281.32.

Solana and DOGE both fell close to 2% in the last 24 hours and are trading at $32.91 and $ 0.6236 respectively.

Algorand suffered a major blow as well and fell by over 2% on the last day.

The market eyes the unemployment data due today with great interest. It can give a possible indication of the future policy guidance of the Fed.

The crypto market is struggling due to the aggressive stance of the Federal Reserve. Despite the continuing threat of a recession, the Fed appears to be in lockstep in their quantitative tightening.

The unemployment data is threatening to further bolster the Feds hawkish stance. It highlights that the economy and the labor market are too strong for the Fed to pivot to monetary easing.

The decision from the Organization of Petroleum Exporting Countries to cut oil supply to raise prices will not help matters. However, President Biden claims that his administration is looking into other options to counter OPECs move.

Minnesota Fed President Neel Kashkari claims that the current economic condition may look a lot like stagflation but is only a transitionary period. However, in a bizarre statement, he claims that there is no evidence that inflation has peaked.

As back-to-back data highlights high inflation, the Fed will eye the CPI data next week before making a decision on the next interest rate hike on the 1st of November.

Nidhish is a technology enthusiast, whose aim is to find elegant technical solutions to solve some of society's biggest issues. He is a firm believer of decentralization and wants to work on the mainstream adoption of Blockchain. He is also big into almost every popular sports and loves to converse on a wide variety of topics.

The presented content may include the personal opinion of the author and is subject to market condition. Do your market research before investing in cryptocurrencies. The author or the publication does not hold any responsibility for your personal financial loss.

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Cryptocurrency Price Today 8 Oct: Altcoins Tank As Inflation Soars - CoinGape

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