Daily Archives: September 3, 2022

Neanderthals died out 40,000 years ago, but there has never been more of their DNA on Earth – The Conversation Indonesia

Posted: September 3, 2022 at 4:57 pm

Neanderthals have served as a reflection of our own humanity since they were first discovered in 1856. What we think we know about them has been shaped and moulded to fit our cultural trends, social norms and scientific standards. They have changed from diseased specimens to primitive sub-human lumbering cousins to advanced humans.

We now know Homo neanderthalensis were very similar to ourselves and we even met them and frequently interbred. But why did they go extinct, while we survived, flourished and ended up taking over the planet?

Neanderthals evolved over 400,000 years ago, most likely from an earlier ancestor Homo heidelbergensis. They were extremely successful and spread across an area from the Mediterranean to Siberia. They were highly intelligent, with brains on average bigger than Homo sapienss.

They hunted for big game, collected plants, fungi, and seafood, controlled fire to cook, made composite tools, made clothes from animal skins, made beads from shells, and were able to carve symbols on to cave walls. They took care of their young, old and weak, created shelters for protection, lived through harsh winters and warm summers, and they buried their dead.

Neanderthals did meet our ancestors on several occasions over the course of tens of thousands of years and the two species shared the European continent for at least 14,000 years. They even mated with each other.

The most significant difference between Neanderthals and ourselves is that they went extinct about 40,000 years ago. The precise cause of their demise still eludes us, but we think it was probably the result of a combination of factors.

First the climate of the last ice age was very variable, shifting from cold to warm and back again, which put pressure on animal and plant food sources and meant Neanderthals constantly had to adapt to environmental change. Second there were never that many Neanderthals, with the overall population never exceeding the tens of thousands.

They lived in groups of five to 15 individuals, compared with Homo Sapiens that had groups of up to 150 individuals. These small isolated Neanderthal populations may have been increasingly genetically unsustainable.

Third there was competition with other predators, particularly the groups of modern humans that emerged from Africa about 60,000 years ago. We speculate that many Neanderthals may have been assimilated into the larger bands of Homo sapiens.

Neanderthals left numerous traces for us to examine tens of thousands of years later, much of which can be seen at the special exhibition we have helped curate at the Natural History Museum of Denmark. Over the past 150 years we have collected fossil bones, stone and wooden tools, found trinkets and jewellery they left behind, uncovered burials, and now mapped their genome from ancient DNA. It seems that 99.7% of Neanderthal and modern human DNA is identical and they are our closest extinct relatives.

Perhaps the most surprising fact was evidence of interbreeding that has left traces of DNA in living humans today. Many Europeans and Asians have between 1% and 4% Neanderthal DNA while African people south of the Sahara have almost zero. Ironically, with a current world population of about 8 billion people, this means that there has never been more Neanderthal DNA on Earth.

The Neanderthal genome also helps us understand more of what they looked like, as there is evidence that some Neanderthals evolved pale skin and red hair long before Homo sapiens. The many genes that are shared between Neanderthals and modern humans are linked to anything from the ability to taste bitter foods to the capacity to speak.

We have also increased our knowledge of human health. For instance, some Neanderthal DNA that might have been beneficial to humans tens of thousands of years ago now seems to cause issues when combined with a modern western lifestyle.

There are links to alcoholism, obesity, allergies, blood clotting, and depression. Recently, scientists suggested an ancient gene variant from Neanderthals might increase the risk of serious complications from contracting COVID-19.

Like the dinosaurs, the Neanderthals didnt know what was coming. The difference is that the dinosaurs disappeared suddenly following a giant meteorite hit from outer space. To the Neanderthals extinction happened gradually. They eventually lost their world, a comfortable home they had successfully occupied for hundreds of thousands of years that slowly turned against them, until existence itself was unsustainable.

In that sense, Neanderthals now serve a different purpose. We see our reflection in them. They didnt know what was happening to them and they had no choice but to continue down the road that eventually led to extinction. We on the other hand are painfully aware of our situation and the impact we have on this planet.

Human activity is changing the climate and is leading straight into a sixth mass extinction. We can reflect on the mess we have landed ourselves in and we can do something about it.

If we dont want to end up like the Neanderthals, we better get our act together and collectively work for a more sustainable future. Neanderthal extinction reminds us that we should never take our existence for granted.

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Ambry Genetics Publishes 43,000 Patient Study Showing Combined RNA and DNA Analysis Identifies Patients Who Are High-Risk for Cancer but Would Have…

Posted: at 4:57 pm

The largest RNA study ever conducted in hereditary cancer analyzed more than 43,000 patients who received Ambrys +RNAinsight testing and found that 1 in 950 had an elusive clinically actionable result that would have been missed by DNA-only testing.

Combined DNA and RNA testing identified cancer risk in an additional 1 out of 79 patients compared to DNA-only testing.

ALISO VIEJO, Calif., August 29, 2022--(BUSINESS WIRE)--Ambry Genetics, a leader in clinical diagnostic testing and a subsidiary of REALM IDx, Inc., announced today the findings of a study that showed paired RNA and DNA genetic testing, conducted at the same time, detected elusive pathogenic variants in 1 of every 950 patients that were missed by DNA testing alone. The findings, published in npj Genomic Medicine, highlight the importance of combining RNA and DNA analysis in hereditary cancer testing to give clinicians and their patients the most accurate and comprehensive genetic data needed to inform patient care and achieve the best outcomes.

According to the National Library of Medicine, as of August 2017, there were approximately 75,000 genetic tests on the market, representing 10,000 unique test types. Unfortunately, many of these DNA-only tests exclude large portions of DNA such as introns, a sequence of DNA that is spliced out before an RNA molecule is translated into a protein. In addition to omitting large portions of introns, DNA-only testing lacks the functional context to determine whether a variant increases cancer risk, which can lead to inconclusive results. These limitations may prevent patients and their families from getting accurate results to inform their preventative or therapeutic care.

Concurrent RNA and DNA testing helps identify more patients at risk by determining if an uncertain result from DNA testing is normal or disease-causing, and expands the range of genetic testing to identify mutations that DNA-only testing misses.

"With our +RNAinsight test we were the first company to offer upfront paired DNA and RNA sequencing to give clinicians and their patients the most accurate and comprehensive information about their cancer risk," said Tom Schoenherr, CEO, Ambry Genetics. "This study confirms that conducting RNA and DNA testing together is critical to help identify high-risk individuals who would have been missed by DNA-only testing."

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Previously, published evidence of the value of RNA sequencing has been limited by studies with small sample sizes and enriched cohorts. This study by Ambry is the largest to examine the impact of paired DNA and RNA analysis in hereditary cancer testing. In the study, tests from 43,524 patients who underwent paired DNA-RNA genetic testing using Ambrys +RNAinsight from March 2019 through April 2020 were examined to determine if the paired sequencing detected more pathogenic variants than DNA testing alone. The analysis identified patients who had disease-causing alterations that DNA testing alone would have misinterpreted. Examining the RNA data resolved variant findings in 549 patients (1 in 79 patients) by providing the required functional data for more accurate interpretation of splicing variants. In addition, the analysis showed that 1 of every 950 patients had a pathogenic deep intronic variant that would not have appeared in DNA testing alone.

The results from the study may underestimate the total clinical impact because some of the patients families who are now eligible for genetic testing were not tested. In addition, the ripple effect created by these updated results extends to past and future patients. These downstream benefits were not quantified in the current study.

"This is the largest study of its kind to show the importance of RNA testing in predicting cancer risk," said Carrie Horton, senior clinical research specialist for oncology and first author of the study. "Its clear that RNA analysis has the potential to become a standard practice for genetic testing to improve hereditary cancer care."

A webinar, open to the media, genetic counselors, clinicians and other interested parties, will be conducted on Thursday, September 15 at 10 a.m. PT to review the study findings. Registration information is here.

Ambrys +RNAinsight was the first test to provide comprehensive gene coverage for RNA analysis to help classify and detect DNA variants associated with a variety of cancers including breast, ovarian, prostate, colon, pancreatic and uterine. +RNAinsight enables more accurate identification of patients with increased genetic risks for cancer, finds actionable results that may otherwise be missed and decreases the frequency of inconclusive results.

About Ambry Genetics

Ambry Genetics, a subsidiary of REALM IDx, Inc., translates scientific research into clinically actionable test results based upon a deep understanding of the human genome and the biology behind genetic disease. It is a leader in genetic testing that aims to improve health by understanding the relationship between genetics and disease. Its unparalleled track record of discoveries over 20 years, and growing database that continues to expand in collaboration with academic, corporate and pharmaceutical partners, means Ambry Genetics is first to market with innovative products and comprehensive analysis that enable clinicians to confidently inform patient health decisions.

View source version on businesswire.com: https://www.businesswire.com/news/home/20220829005605/en/

Contacts

Media Contact

Brad LottermanCommunications DirectorREALM IDx949-401-0465blotterman@realmidx.com

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Worker shortage is driving up construction costs in the Triangle – WRAL News

Posted: at 4:56 pm

By Matt Talhelm, WRAL reporter

A struggle to hire construction workers is delaying and driving up the cost of building projects in the Triangle. A new survey from the Associated General Contractors of America says of general contractors in the state, 100% of them are having trouble filling positions.

The survey says the shortage threatens the progress on billions of dollars worth of new infrastructure projects.

"We've got probably, 22, 23 projects going on right now, and there's not a single one of them where us, or our subcontractors, don't wish we had more people, said Charlie Wilson, the president of C.T. Wilson Construction Company, which was founded in 1952 by his grandfather.

Ryan O'Keefe started with C.T. Wilson Construction Company sweeping floors and doing demolition. He's now a superintendent managing projects and crews. The shortage of workers is getting in the way of O'Keefe adding to his headcount under hard hats.

"It's pretty much across the board, all the trades plumbing, electrical, mechanical, sprinkler, carpentry, sheet rock, all that," said O'Keefe.

The AGCA's survey points to a lack of skilled labor as the biggest problem filling positions.

"The reality is that there are too many open positions and not enough people to fill them," said Betsy Bailey, who represents the statewide association of contractors.

Bailey said contractors have more work than they can take on, especially in the Triangle.

"Youve got a lot of public investment, and thats spurring a lot of private investment, a lot of growth in the state, so there are just a ton of projects out there right now," she said.

More projects are in the works with an influx of funding for infrastructure upgrades to roads, bridges, broadband and public buildings.

"I don't think they'll be impossible," said Wilson. "They'll definitely probably cost more and take longer to do."

Wilson said his company has raised wages and is offering bonuses to try to recruit workers.

"There's a lot of other industries competing against us for employees," he said.

O'Keefe said he moves his crews around as he can to keep projects on pace.

"We just try to get creative to still meet the deadline with the shortage of help," said O'Keefe.

The trade association here is getting ready to launch a Construction Bootcamp at a dozen or more community colleges across the state. Students will graduate from the free, eight-week program with two construction certifications to start work immediately to help fill some of these positions.

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Chris Rock Says Will Smith Oscars Slap Followed His ‘Nicest’ Joke – We Got This Covered

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Image via Netflix

It was the slap heard (and watched) round the world, and Chris Rock is still getting mileage out of it.

During a European comedy tour, Rock brought up the incident in which Will Smith slapped the comedian on national television. During a show in Liverpool, England, he asked the audience, as reported by Deadline, Did that sh*t hurt? Goddamn rightThe motherf*cker hit me over a bullsh*t joke, the nicest joke I ever told.

This years Academy Awards have gone down in infamy for Smiths bad decision. On a night when he should have been celebrated for finally taking home the Oscar for Best Performance by an Actor in a Lead Role for his work in King Richard, all anyone talks about is The Slap. At the awards show in March, Rock, the host of the 94th Oscars, made a joke at the expense of Smiths wife, Jada Pinkett Smith, who suffers from the skin condition alopecia. Smith seemed to initially laugh at the joke before charging the stage to slap the comedian. After returning to his seat, Smith yelled obscenities at Rock, all on national television.

Smith has since apologized for his behavior and resigned from the Academy of Motion Picture Arts & Sciences, but its apparently still too soon for most fans. For the time being, hes remained relatively quiet. But, of course, this is Hollywood, and itll all be forgotten when the Fresh Prince has his next blockbuster hit.

Meanwhile, Rock is still talking about his awkward Oscars moment. In May, an audience member tackled Dave Chappelle on stage during his set at the Hollywood Bowl for the Netflix Is a Joke Fest. Rock took to the stage in the aftermath and quipped to the audience, Was that Will Smith?

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This Band Made a $3.44 Music Video. Then They Went Viral – WIRED

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Smoko originally blew up when a local surf shop posted it on its Facebook page. By the time the video surpassed a half a million views, the Chats were being profiled on the local news. Soon after, they started touring the world. Its just a constant pinching-yourself moment, Sandwith says. How do these people know about us? Let alone like us enough to come watch us?

And all this for a band that is almost calculatingly insular. The band name came from a term drummer Matt Boggis picked up in Sydney. All of a sudden, he was like, thats chat, this is chat. We were like, What the fuck does that mean? Boggis explains, Its just something you say when somethings really shit. So they named themselves the Chats. Then they kept pumping out songs informed by the particular world view of their friend group. Their latest single, Ive Been Drunk in Every Pub in Brisbane, spends a good chunk of its 97-second run time naming said bars. It was almost an in-joke, Sandwith says, to use all manner of vernacular that only certain people from our area would understand. Not even Australian people! Just people from our town.

When touring abroad, particularly in the US, Sandwith says, theres a bit of weird tokenism. People are very much like, Oh, can you say Gday? I guess Australia is almost a mythical place they imagined. What differentiates the Chats in particular is that theyre a rare media representation for the Sunshine Coast, or Sunny Coast, in the northern state of Queensland. Queensland in general is seen as more of a redneck kind of place, especially to people from the southern states, Sandwith explains. But to me, its just like, a place. And its their eternal muse. The more insular they go, the more the world loves it. Its just our world. Its what we see and what we do. I mean, it wouldnt make heaps of sense for us to write a song about fucking Paris or something.

When Smoko first started doing numbers, Sandwith didnt get carried away. I remember thinking, I know how the internet works! Somethings cool for a bit and then its like pffffft. Everyone could just go back to not giving a fuck about us next week. But here they are, five years later. I didnt think it would stand the test of time, where people would still care about us, he says. But they still do!

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The Predictions: Can Cabrillo keep up with Lompoc in the Big Game? – Santa Ynez Valley News

Posted: at 4:56 pm

There's some rivalry action on tap for this weekend.

Lompoc and Cabrillo are set to square off in the Big Game and Arroyo Grande and San Luis Obispo meet in their big SLO County throwdown.

That means it's the perfect time to make some predictions.

Lompoc (2-0) at Cabrillo (2-0)

The last time the Big Game had this much hype was in 2011. Then Cabrillo and Lompoc actually played twice, with Lompoc beating Cabrillo in the regular season finale and then 21-0 in the CIF Southern Section Northwest Division title game.

A lot has changed since then. Cabrillo and Lompoc are now in the CIF Central Section and a part of the Central Coast Athletic Association.

Cabrillo last started 2-0 in the 2014 season under then coach Don Willis. Cabrillo also started the 2011 season with a 2-0 record.

Lompoc coach Andrew Jones has never lost to Cabrillo since taking over the head coaching job in 2010. Is this the year Cabrillo can knock off the Braves? I don't see it happening.

Cabrillo is clearly much improved this year, but Lompoc is Lompoc. The Braves have beaten the Conqs 17 of the last 19 times. Too much speed, too much talent and Lompoc is too well coached.

Cabrillo, though, can turn its focus to Ocean League play where the Conqs should be much more competitive.

The Pick: Lompoc 42, Cabrillo 6.

Righetti (0-2) at Pioneer Valley (0-2)

The Warriors haven't won yet, but they've played two of the top teams in Santa Barbara County, with losses to Bishop Diego and Santa Barbara.

The Panthers lost to Bakersfield Independence 7-0 in their opener and then were blasted by Lompoc 54-7 last week.

Pioneer Valley just doesn't have the offense to keep up with Righetti. People tend to look at Righetti's record, but remember the Warriors play tough teams, whether its in league or non-league.

Righetti has too much firepower on offense and just too much talent all over the field.

The Pick: Righetti 42, Pioneer Valley 8

Arroyo Grande (0-2) at San Luis Obispo (2-0)

This rivalry is a lot like the Big Game. After not being very competitive over the last 20 years, there's some intrigue in this one. Arroyo Grande has beaten SLO 14 of the past 18 times the teams have played.

This time, though, the once underdogs are now the favorites. San Luis Obispo should win this game. The Eagles did beat the Tigers 42-14 a year ago, but SLO has played well this year while Arroyo Grande has struggled. It should be close, but the Tigers are the pick. They've beaten Nipomo and Caruthers, two middling programs, but SLO has confidence and momentum on its side.

The Pick: SLO 35, Arroyo Grande 27.

Morro Bay (1-1) at Santa Ynez (1-0)

The Battle of the Pirates is back! Santa Ynez looked great in its 35-0 win over Atascadero in the opening week of the season and was off last week. Morro Bay lost to San Marcos and then beat Carpinteria 41-7 last year. Carp went 0-10 a year ago.

Santa Ynez should cruise in this one, though Morro Bay isn't a team to sleep on. They did win the CIF Central Section Division 6 title a year ago and Nicky Johnson can sling the rock all over the field. One thing is for sure: The Pirates will win this game.

The Pick: Santa Ynez 42, Morro Bay 20.

East Bakersfield (0-2) at Templeton (0-1)

Templeton started the season with a bye and then lost to Coalinga 39-15 on Friday. East lost to Santa Maria 24-22 and to Bakersfield Golden Valley 28-7.

This one could be close.

The pick: Templeton 29, East 22.

Paso Robles (0-1) at Atascadero (0-2)

This used to be THE SLO County rivalry. It'll probably get to that level in the future, but it's not there now.

Paso Robles has gone 12-6 against Atascadero over the last 18 years. Atascadero lost to Santa Ynez 35-0 in its opener and was beat by North Bakersfield 37-14 in its second game.

Paso Robles was smacked by Kingsburg 35-0. Kingsburg is really good. Paso Robles is just in another league from Atascadero. Literally. Paso is up in the Mountain and Atasadero is down in the Ocean.

Look for Leo Kemp to have a big night running the ball for Paso. Atascadero has some pieces, but the Hounds aren't quite there yet.

The Pick: Paso Robles 44, Atascadero 18.

McLane (1-1) at Mission Prep (0-1)

McLane has a 20-14 win over Mendota this year and was beaten 14-6 by Porterville.

Mission Prep was beaten by a decent Bakersfield Christian squad. Mission Prep just has too much talent for McLane.

The Pick: Mission Prep 39, McLane 9.

Saturday

Nipomo (0-2) at Santa Maria (1-1)

This is a tough one. The Saints looked pretty solid in their opener beating East Bakersfield 24-22 and then was beat handily by San Marcos. Now they get 0-2 Nipomo, which hasn't had a good start to the season, falling 35-0 to SLO and 13-6 to Cabrillo.

If the Saints have made any progress over the past 12 months, they should beat a team like Nipomo. (This game has been moved to Saturday night at 7 p.m. due to an officials shortage).

The Pick:Santa Maria 24, Nipomo 10.

8-man

Orcutt Academy (0-1) at Valley Christian Academy (0-0)

There's some great 8-man action on tap Saturday. The Spartans were too big and too strong for the Lions a few years ago and the teams hadn't played each other. The matchup now figures to be much more competitive. VCA has a lot of returners with QB Sean Swain and do-everything standout Jacob Sanders. I'll go with the Lions. Expect lots of points.

The Pick: VCA 66, Orcutt Academy 50.

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Franz Ferdinand at the Rooftop at Pier 17 / August 13, 2022 – Aquarian Weekly

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Franz Ferdinand is a rock band. Franz Ferdinand is a pop band. Franz Ferdinand is a dance band.

Formed in 2002 in Glasgow, Scotland, Franz Ferdinand across five studio albums also has been labeled as indie rock, post-punk revival, dance-punk, dance-rock, and art rock, all of which may be partially correct. The pop-rock-dance tag seems like the best fit, however, exhibited by the success of Take Me Out in 2004 and Do You Want To in 2005 in the United States.

Franz Ferdinand presently consists of two founding members, vocalist/guitarist Alex Kapranos and bassist Bob Hardy, along with keyboardist Julian Corrie, rhythm guitarist Dino Bardot, and drummer Audrey Tait. The bands newest product is a greatest hits package,Hits to the Head, released on March 11. The album collected many of the bands better-known songs, and included two new songs which the band released in advance of the album in 2021.

With no new music since 2018, Franz Ferdinand performed the concert that anyone would have expected a retrospective celebrating the bands 20 years. For the most part, the songs were slick, high-energy pop-rockers, given a stronger presence by Alex Kapranos effervescent showmanship. Kapranos wide-legged jumps repeatedly drew cheers from the audience.

Kapranos was in fine voice, and the well-rehearsed band played a tight support. Flourishes were added to some of the songs, including a slightly longer introduction to Take Me Out. The live setting made the adrenaline-pumping faster songs that much more dynamic.

Toward the end of the set, roadies brought a set of tom toms to the center of the stage. New drummer Audrey Tait moved forward to beat a rhythm. The other musicians joined her in playing percussion around the stage, even using her main drum kit. This lasted only a few moments, but gave another sparkle of flash to the concert.

Franz Ferdinand lit and maintained a spirit of enjoyment throughout its performance. The Hits to the Head tour was a rousing victory lap for a band whose new music output has diminished in recent years. It also was an opportunity for the fans to enjoy the bands catalog the way it is best appreciated live and loud.

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Top Quarterback Bets for 2022: Will Russell Wilson Lead the League in Passing yards? – Sportsbook Review

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Quarterback Russell Wilson of the Denver Broncos runs onto the field before a preseason game against the Minnesota Vikings at Empower Field at Mile High on August 27, 2022 in Denver, Colorado. Photo by Dustin Bradford/Getty Images/AFP.

Can Russell Wilson lead the league in passing yards? Let's examine that and more with our top NFL quarterback bets for 2022.

The first game of the 2022 NFL season is officially one week away. Yes, life will be worth living again, and we'll also be able to enjoy our Sundays shortly after the Thursday night opener. Maybe I'm speaking for myself, but I'm sure you fall into this category too. Don't deny it.

With the season fast approaching, there's not much time left to make futures bets. Let's break down a few of the top quarterback futures plays for the 2022 NFL season (odds via DraftKings Sportsbook, FanDuel Sportsbook, and Caesars Sportsbook).

This number is slightly over 350 yards fewer than what Carr finished with in 2021.

He now gets the offensive-minded Josh McDaniels as his head coach. McDaniels is adept at tailoring game plans around individual players. Carr will also be throwing to his former college teammate, Davante Adams. He's been the NFL's best receiver for the past two seasons while racking up nearly 3,000 yards and 29 touchdowns, and Adams has already built up chemistry with Carr.

The passer also works with other dynamic receiving weapons in Darren Waller and Hunter Renfrow.

Another factor in Carr's favor here is playing in the AFC West.Each team boasts star quarterbacks and elite offensive weapons, and the Raiders will consistently be in shootouts.

Everything aligns perfectly for Carr to register a significant passing yards total again.

Check out the latest comprehensive and most trustedSportsbook Reviewsby SBR.

Mayfield only exceeded this total twice during his four years with the Cleveland Browns. He's now on a Carolina Panthers team that leans on defense.

The signal-caller will benefit from throwing to solid weapons in DJ Moore and Robbie Anderson. But we can assume he'll be checking down or handing it off to the lethal Christian McCaffrey often. Run CMC is the focal point of Carolina's offense, and head coach Matt Rhule will lean on him and the defense to do most of the work.

The Panthers will also face the 12th-hardest schedule in 2022, and a brutal stretch in October that includes the Los Angeles Rams and Tampa Bay Buccaneers. Mayfield is a viable NFL starter, but he's nothing more than a game-manager. Don't expect him to be slinging the rock all over this season.

This will finally be the year we see Russ cook. Wilson now finds himself on a Denver Broncos team with exceptional receiving talents, and a head coach inNathaniel Hackett who will allow him to play freely offensively.

In Seattle, head coach Pete Carroll insisted on running the ball.Though the Broncos boast a solid running back duo in Javonte Williams and Melvin Gordon, Hackett and offensive coordinator Justin Outten will let Wilson air it out.

Much like Carr, Wilson will be letting it fly in games against AFC West foes, and he'll be throwing to a fantastic receiving tandem in Jerry Jeudy and Courtland Sutton. Sutton is an elite red-zone and outside target, and Jeudy is a top-tier option between the numbers. Third-year receiver and downfield threat KJ Hamler is poised to take the next step, too, creating even further problems through the air for opposing defenses.

The stars are finally aligning for Wilson to produce his best offensive season yet, and it wouldn't be surprising to see him lead the NFL in passing yards in 2022.

Here are ourtop-rated sportsbooks:

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SEE ALSO: Allpicks,odds, andsports betting news. Be sure to check out SportsbookReview.coms communityforumsandbetting tools.

Jordan Anderson is a Content Editor and Sports Betting Analyst at SportsbookReview.com. He's previously written at BettingPros and has spent most of his career in content marketing. Jordan's first love is hockey, and he covers the NHL, the NFL, and PGA. A long-time suffering Buffalo Bills fan, he is thoroughly enjoying the Bills' current wave of success before they ultimately break his heart again. Jordan holds a bachelor's degree in Sport Management from SUNY Cortland and a Master's in Integrated Marketing Communication from Marist College. You can find him watching sports and playing hockey and golf in his free time.

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Muse: Will of the People Review Oozing With Paranoia and Chaos – Music Feeds

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Muses Will of the People is Music Feeds Album of the Week. Tiana Speter reviews.

Muse have been making a living blasting social, technological, and interpersonal dystopias since exploding into the mainstream at the turn of the century. It seems inevitable that the British trio would emerge from years of global unrest armed with an album that leans heavily into these themes. But while Muses ninth album,Will of the People, goes hard on the alarm-raising fanfare, its also an authentic snapshot of the current state of the world.

Blending elements from Queen and Radiohead with prog experimentation and straight-up bombast, Muse have outlasted many of their contemporaries largely through taking steep diversions from album to album. Theyve embraced concept albums, made excursions into dubstep and rock opera, and built an identity founded in predictable unpredictability.

WithWill of the People, the band shed the fictionalised aspects of 2018sSimulation Theory in favour of something that chimes with the current news cycle. Many tracks here ooze with paranoia and chaos, but theres also a lot of fun to be found in this soundtrack to the apocalypse.

Will Of The People is a whirlwind of genres, with metal, glam rock, synthpop and arena rock all contributing to the mix across the albums 38 minutes. In the wrong hands, thisgenre-cluster might lead to self-implosion, but with front personMatt Bellamy at his larger-than-life best throughout, the grandiosity feels like a familiar friend returning home to deliver some hysterical messages.

Opening track, Will Of The People, is a stomping call to arms that borrows the chugging beat from Marilyn Mansons The Beautiful People; Wont Stand Down and Kill Or Be Killed hint at the sonic acrobatics of earlier Muse. Amid Bellamys trademark falsetto, Chris Wolstenholmes fuzzy bass and Dom Howards thunderous drums, there are lashings of ethereal piano and heavy metal guitar playing, including a Van Halen-aping solo on standout track You Make Me Feel Like Its Halloween.

Bellamys lyrics encompass Black Lives Matter, wildfires, political discourse, the COVID-19 pandemic, online vitriol, and even the January 6 attack on the US Capitol.The album closes with We Are Fucking Fucked, the title of which is a blunt summary of the agenda Muse have long pursued. But in 2022, these paranoid political themes feel especially salient, even given the surrounding sonic absurdity.

Will Of The People may at times be overdressed for dinner, but it isnt your average pandemic moan and groan. As Bellamy himself declares, Welcome to the desecration, baby / Well build you right up and well tear you down / Welcome to the celebration, baby / The chances are turning, this future is ours. If this is how the world ends, its with a bang, not a whimper.

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Muse: Will of the People Review Oozing With Paranoia and Chaos - Music Feeds

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Moosebots gear up for another year of robotics – kdll.org

Posted: at 4:54 pm

The 19 students and one teacher at the Moose Pass School one of the smallest on the Kenai Peninsula arent the only ones roving around the schools three classrooms.

There are also robots.

Nine-year-old Maddy Aigeldinger holds a small Lego robot that sits no taller than three inches atop a pair of tiny blue wheels. She said each of their names: there's Ottie, the favorite, and then L5 and Bob the Destroyer, their testing robots.

Aigeldinger is one of the Moosebots the Moose Pass Schools Lego robotics team. The Moosebots design and build robots that they put to the test in annual competitions against schools across Alaska.

Although the Moose Pass school is tiny, its team still brings home trophies year after year. In 2021, Aigeldinger and her fellow Moosebots won the coveted Robot Design Challenge at the state-level competition. In the past, theyve competed internationally in the FIRST Lego League Challenge a global robotics and design competition for elementary and middle schoolers.

On the first day of robotics this year, students buzzed with excitement about getting back to work on their robots.

Wendy Bryden brought Lego robotics to the Moose Pass School eight years ago when her two sons, both passionate about robotics, were students.

Bryden didnt have any experience with robotics then.

I knew Legos, but I didnt know much about programming. Im a mom, Im not an engineer, she said.

But Bryden learned along with the kids. Today, she organizes Lego robotics competitions for the entire state of Alaska. And although her sons have since graduated, she still works with students in Moose Pass every week to design robots and build the Lego bridges and obstacles they interact with.

For the statewide competition last year, held remotely due to the pandemic, the Moosebots designed a device to stop boxes from getting damaged at the post office by dividing them by size. They even presented the device to the local postmaster.

Sometimes, Bryden said, the teams go on to get their designs patented

The theme for this years statewide competition is energy. Students are working on designing a water wheel, modeled after a historic Moose Pass landmark. Bryden said theyre also thinking about the Grant Lake hydroelectric project while they work with the theme.

She said local impact is one of the core values the FIRST Lego League highlights in its mission. Its a set of values the students know well.

Teamwork, inclusion, impact, fun, discovery, innovation, Ruby Boyle, one of the Moosebots, read off.

Sandra Barron, the teacher at Moose Pass, said an important part of life at Moose Pass is that every student is involved in everything.

She said when theres a school play, everyones in it. And when theres a robotics competition, everyone is involved. Boyle said thats a key part of their success.

Its really important, because youve gotta work together to make things, she said.

With fewer than 20 students from kindergarten to eighth grade, the Moose Pass School has always been a place where students across age groups work together on the same projects.

Bryden said grade level isnt important to students, which shes found to be a really great model for education. Thats been true during their robotics lessons, when she often has an older group of students mentoring younger ones.

I think thats such a huge part of this program, that the kids teach each other what they know, she said.

Bryden also hopes the program helps students improve their problem solving skills and that it maybe even kickstarts lifelong passions for engineering.

She said that was the case for her sons.

I think part of this definitely inspired both of my kids to think like engineers, and to potentially want to pursue that as a career, Bryden said.

Its true for some current Moosebots, as well but not all of them. While Ruby Boyle said engineering might be in her future, Maddy Aigeldinger said shes staying committed to her life-long dream of owning a donut shop.

The Moosebots will compete in the annual statewide FIRST Lego League competition this winter.

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Moosebots gear up for another year of robotics - kdll.org

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