Daily Archives: August 15, 2022

Selenium Yeast Market to Exceed US$ 375.9 Mn by 2032 as Adoption of Organic Selenium Yeast as a Health Supplement Grows | Future Market Insights, Inc….

Posted: August 15, 2022 at 6:44 pm

NEWARK, Del, Aug. 11, 2022 (GLOBE NEWSWIRE) -- The global selenium yeast market is set to witness growth at a CAGR of 3.7% and top a valuation of US$ 375.9 Mn by 2032, as per Future Market Insights (FMI). Selenium as an important trace element is required to maintain good health and a balanced nutrient profile.

Selenium yeast is an essential compound product containing selenoproteins which is required by several other important anti-oxidants to convert hormones from inactive to active form. As an optimal selenium level is very important in order to maintain a healthy and proper body function, intake of selenium-based diet and supplements should be accurate, which can be provided by selenium yeast perfectly.

Selenium yeast in any form is utilized by selenoprotein synthesis of the body and it works best when organically sourced. This is easily metabolized as a cellular storage form of selenium, known as hydrogen selenide.

Selenomethionine absorption works best, as organic selenium yeast uses same active transport mechanism like methionine, which is an essential amino acid. This can only be dietary selenium which is more efficient than inorganic forms of selenium in terms of selenomethionine absorption. Some selenium yeast supplements include vitamin E as well to further facilitate selenium absorption and increase its antioxidant effects.

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Key Takeaways from Market Study

Organic selenium yeast supplements are essential due to several facilities it provides to human health including higher anti-oxidant activities and other nutrients absorption, which is driving the growth in food, pharmaceuticals, and animal feed industries over the forecast period, says a Future Market Insights analyst.

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Competitive Landscape

Key selenium yeast brands are focusing on sustainable and organic product developments, while extending the product portfolio with extensive research procedures and several modifications to capture more market share in global arena and to further boost the industry growth.

Explore More Valuable Insights

Future Market Insights, in its new report, offers an impartial analysis of the global selenium yeast market, presenting historical data (2017-2021) and estimation statistics for the forecast period of 2022-2032.

The study offers compelling insights based on nature (organic and conventional), grade (food grade and feed grade), and application (food & beverages, nutraceuticals & dietary supplements, animal feed, and others), across seven major regions of the world.

About Food & Beverage Division at Future Market Insights

The Food & Beverage team at Future Market Insights provides all the necessary insights and consulting analysis to fulfill the unique business intelligence needs of clients worldwide. With a catalog of more than 500 reports pertaining to the latest statistics and analysis from the food & beverage industry, the team is happy to help with every business intelligence research and consulting requirement.

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Table of Content

1. Executive Summary

1.1. Global Market Outlook

1.2. Demand-side Trends

1.3. Supply-side Trends

1.4. Technology Roadmap Analysis

1.5. Analysis and Recommendations

2. Market Overview

2.1. Market Coverage / Taxonomy

2.2. Market Definition / Scope / Limitations

3. Market Background

3.1. Market Dynamics

3.1.1. Drivers

3.1.2. Restraints

3.1.3. Opportunity

3.1.4. Trends

3.2. Scenario Forecast

3.2.1. Demand in Optimistic Scenario

3.2.2. Demand in Likely Scenario

3.2.3. Demand in Conservative Scenario

3.3. Product launches & Recent Developments

3.4. Macro-Economic Factors

3.5. Value Chain Analysis

Read More TOC

Have a Look at Related Research Reports of Food and Beverage

Nutritional Yeast Market Forecast: Nutritional yeast market size exceeded USD 201.4 Mn in 2022 and is estimated to grow at over 14.0% CAGR between 2022 and 2032

Organic Dry Yeast Market Demand: Organic dry yeast is yeast that is processed and grown according to organic farming principles. Organic dry yeast converts sugar and starch into carbon dioxide bubbles and alcohol, making them useful in bread, beer and wine production

Inactive Dried Yeast Market Outlook: Conventional inactive dried yeast is expected to hold about 96.9% share in the global inactive dried yeast market. Its easy availability and rising demand in the animal feed industry are supporting expansion of the conventional inactive dried yeast segment in the global market

Chelated Selenium Market Analysis: Chelated selenium is an essential element of glutathione antioxidant agent which helps in overcoming the effect of free radicals include premature aging. Additionally, chelated selenium has multiple applications such as developing and functioning of cells in human and other animals

Confectionery Ingredients Market Value: Valued at US$ 83,276 Million in 2022, the market for confectionery ingredients is expected to showcase substantial growth. From 2022-2032, sales of confectionery ingredients are forecast to incline at a 5.7% value CAGR, reaching US$ 130,743.3 Million

Alternative Protein Market Sales: The global alternative protein market garnered a market value of US$ 73.44 Billion in 2022 and is expected to accumulate a market value of US$ 496.56 Billion by registering a CAGR of 21% in the forecast period 2022-2032

Dry Mixes Market Growth: The global dry mixes market is anticipated to be valued at US$ 8,700.0 Million in 2022, forecast to grow at a CAGR of 5.9% to be valued at US$ 15,434.0 Million from 2022 to 2032

Melaleuca Alternifolia Market Size: The melaleuca alternifolia market is anticipated to achieve a CAGR of 7.4% through 2032 and is expected to reach a value of US$ 48 Million in 2022. By 2032, the melaleuca alternifolia market size is projected to increase to US$ 98 Million

Catalase Market Trends: The global catalase market is anticipated to be valued at US$ 387.4 Million in 2022, forecast to grow at a CAGR of 2.9% to be valued at US$ 516.6 Million from 2022 to 2032

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Selenium Yeast Market to Exceed US$ 375.9 Mn by 2032 as Adoption of Organic Selenium Yeast as a Health Supplement Grows | Future Market Insights, Inc....

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Animal Feed Additives Market is Estimated to Progress at a CAGR of 5.2% during the Forecast Period, notes TMR Study – GlobeNewswire

Posted: at 6:44 pm

Wilmington, Delaware, United States, Aug. 09, 2022 (GLOBE NEWSWIRE) -- Transparency Market Research Inc. - The revenue of animal feed additives market is likely to surpass US$ 66.23 Bn by 2031. The global market is expected to rise at a CAGR of 5.2% during the forecast period, from 2021 to 2031. Amino acids are crucial for many biological functions, such asmetabolism,food consumption, digestion, and also reproduction Methionine, one of the several forms of amino acids, is mostly employed in the poultry business, whereas lysine is utilized in the pork business. Extensive use of amino acids is likely to emerge as largest opportunity for animal feed additives market in the near future.

Large producers of animal feed additives are vying for certifications from reputable organizations that are in charge of protecting the welfare of animals and upholding high standards for food quality. The standards andquality of company's products could be raised, and their acceptance rate in various local markets could rise, by acquiring these certifications. This factor is a recent developments in the animal feed additives market.

Producers of animal feed additives from a variety of sources are increasingly shunning globalization trends in favour of a localized strategy that entails procuring raw ingredients from certain regions and countries. Many producers of feed additives are also building local distribution networks, which aids in insulating their companies from external influences and risky trade regulations.

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Key Findings of Market Report

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Global Animal Feed Additives Market: Growth Drivers

Global Animal Feed Additives Market: Key Players

Some of the key market players are

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Global Animal Feed Additives Market: Segmentation

Type

Source

Form

Livestock

By Regions

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Animal Feed Additives Market is Estimated to Progress at a CAGR of 5.2% during the Forecast Period, notes TMR Study - GlobeNewswire

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The Worldwide Food Fortifying Agents Industry is Expected to Reach $128 Billion by 2027 – PR Newswire

Posted: at 6:44 pm

DUBLIN, Aug. 15, 2022 /PRNewswire/ -- The "Food Fortifying Agents Market by Type (Minerals, Vitamins, Carbohydrates, Prebiotics, Probiotics), Application (Cereal & Cereal-based Products, Bulk Food Items), Process (Drum Drying, Dusting) and Region - Global Forecast to 2027" report has been added to ResearchAndMarkets.com's offering.

The food fortifying agents market is projected to reach USD 128.0 Billion by 2027 growing at a CAGR of 10.1% from 2022 to 2027. Increasing consumer awareness with respect to the health benefits associated with fortifying agents and growing preventive healthcare measures undertaken by the consumers is proliferating the demand for food fortifying agents market.

The vitamins segment dominates the market with 26.0% of total market share in terms of value

Vitamins, also known as vital amines, are essential in micro quantities to ensure normal metabolism and growth of the body. They are classified as micronutrients because they are normally required in small amounts; usually a few milligrams (mg) or micrograms (?g) per day. A total of 13 vitamins have been identified, namely, vitamin A & provitamin A, vitamin B (B1, B2, B3, B5, B6, B9, and B12), vitamin C, vitamin D, vitamin E, and vitamin K.

Most vitamins cannot be synthesized by the body, as a result of which, they must be obtained through external sources. An exception is vitamin D, which can be synthesized by the action of sunlight on the skin. The segment held the largest share owing to rising risks of chronic diseases and consumer awareness regarding benefits of vitamins.

Food fortifying agents have high demand in bulk food items industry

The dominance of this application can be attributed due to the increasing demand for high-quality food products and changing health trends, which in turn increases the demand for food fortifying agents. The market is driven by the growing health awareness among consumers, urging companies to offer various food fortifying agents for various applications, such as functional foods, beverages, dietary supplements, infant formula, and dairy, due to their health benefits.

Fortification of bulk food items is an appropriate vehicle for the micronutrient and is widely consumed by the general population; it is intended for intervention programs to address the deficiency in a specific target population.

Asia Pacific is projected to witness the growth of 10.8% during the forecast period

The food fortifying agents market in Asia Pacific is growing at a CAGR of 10.8% due to the increasing health-consciousness among the consumers and the multi-benefits of food fortifying agents. The Asia Pacific food fortifying agent market is competitive in nature having a large number of domestic and multinational players competing for market share.

Emphasis is given on the merger, expansion, acquisition, and partnership of the companies along with new product development as strategic approaches adopted by the leading companies to boost their brand presence among consumers.

Key Topics Covered:

1 Introduction

2 Research Methodology

3 Executive Summary

4 Premium Insights4.1 Brief Overview of the Food Fortifying Agents Market4.2 North America: Food Fortifying Agents Market, by Application and Country4.3 Food Fortifying Agents Market, by Type4.4 Food Fortifying Agents Market, by Application4.5 Food Fortifying Agents Market, by Application and Region

5 Market Overview5.1 Introduction5.1.1 Drivers5.1.1.1 Consumer Awareness About the Health Benefits of Fortifying Agents and Increasing Focus on Preventive Healthcare5.1.1.2 Increasing Demand for Fortifying Agents in Dietary Supplements5.1.1.3 Increase in Application Profiling and Existing Applications Finding New Markets5.1.1.4 Increasing Cases of Chronic Diseases5.1.2 Restraints5.1.2.1 High Cost Involved in R&D Activities5.1.3 Opportunities5.1.3.1 Growing Applications of Food Fortifying Agents5.1.3.2 Technical Assistance by Governments5.1.3.3 Growing Demand from Emerging Economies5.1.4 Challenges5.1.4.1 Price Differences in Fortified Vs. Non-Fortified Products5.1.4.2 Multi-Page Labeling on the Rise

6 Industry Trends6.1 Introduction6.2 Supply Chain Analysis6.3 Key Industry Insights6.4 Porter's Five Forces Analysis6.4.1 Threat of New Entrants6.4.2 Threat of Substitutes6.4.3 Bargaining Power of Suppliers6.4.4 Bargaining Power of Buyers6.4.5 Intensity of Competitive Rivalry6.5 Key Conferences & Events in 2022-2023

7 Regulatory Framework7.1 Overview7.2 North America7.2.1 Canada7.2.2 US7.2.3 Mexico7.3 European Union (Eu)7.4 Asia-Pacific7.4.1 Japan7.4.2 China7.4.3 India7.4.4 Australia & New Zealand7.5 Rest of the World (Row)7.5.1 Brazil7.6 Dietary Trends7.6.1 Recommended Nutrient Intakes

8 Food Fortifying Agents Market, by Type8.1 Introduction8.2 Minerals8.2.1 Increasing Application of Minerals in Food Products due to Rising Health Benefits8.3 Vitamins8.3.1 Growing Consumer Awareness of Cardiovascular Health8.4 Lipids8.4.1 Rising Consumption of Omega-3 Fatty Acids to Reduce the Risk of Chronic Heart Diseases8.5 Carbohydrates8.5.1 Growing Application of Nutrients in Food & Beverage Products8.6 Proteins & Amino Acids8.6.1 Increasing Health Benefits of Proteins & Amino Acids to Support Market Growth8.7 Prebiotics8.7.1 Growing Preference for Natural Alternatives Over Conventional Medicines8.8 Probiotics8.8.1 Growing Application of Probiotics in Dietary Supplements8.9 Other Types8.9.1 Increasing Application of Other Food Fortifying Agents to Maintain Spine Health Supports Market Growth

9 Food Fortifying Agents Market, by Application9.1 Introduction9.2 Cereals & Cereal-Based Products9.2.1 Fortified Breakfast Cereals Play a Significant Role in Ensuring Nutritional Adequacy9.3 Dairy & Dairy-Based Products9.3.1 Enhances the Nutritional Value of Dairy & Dairy-Based Products9.4 Fats & Oils9.4.1 Increasing Popularity of Fortified Edible Oil Among Consumers9.5 Bulk Food Items9.5.1 Fortification of Bulk Food Items is an Appropriate Vehicle for Micronutrients9.6 Beverages9.6.1 There is Increasing Awareness Among Consumers Regarding Gut Health and Immunity9.7 Infant Formula9.7.1 Rising Economic Growth of Consumers with a Preference for Convenience Foods9.8 Dietary Supplements9.8.1 Growing Omega-3 Supplements' Demand due to Numerous Health Benefits9.9 Other Applications9.9.1 Increasing Focus on Feed, with Increased Opportunities in Dairy and Meat Industries, Contributes to the Growth of this Segment

10 Food Fortifying Agents Market, by Process10.1 Overview10.2 Types of Technologies and Processes Used in Food Fortification10.2.1 Powder Enrichment10.2.2 Premixes and Coatings10.2.3 Drum Drying10.2.4 Dusting10.2.5 Spray Drying Under the Microencapsulation Process

11 Food Fortifying Agents Market, by Region

12 Competitive Landscape12.1 Overview12.2 Market Share Analysis, 202112.3 Historical Revenue Analysis of Key Players12.4 Company Evaluation Matrix for Key Players12.4.1 Stars12.4.2 Pervasive Players12.4.3 Emerging Leaders12.4.4 Participants12.4.5 Food Fortifying Agents: Footprint, by Type (Key Players)12.5 Company Evaluation Matrix for Other Players12.5.1 Progressive Companies12.5.2 Starting Blocks12.5.3 Responsive Companies12.5.4 Dynamic Companies12.6 Competitive Scenario12.6.1 New Product Launches12.6.2 Deals12.6.3 Other Developments

13 Company Profiles13.1 Key Players13.1.1 Cargill13.1.2 Ingredion13.1.3 Tate & Lyle13.1.4 Dsm13.1.5 Arla Foods Amba13.1.6 Chr. Hansen Holding A/S13.1.7 Dupont13.1.8 Archer Daniels Midland Company13.1.9 Basf Se13.1.10 Nestle Sa13.1.11 Wenda Ingredients, LLC13.1.12 Royal Cosun13.1.13 Stratum Nutrition13.1.14 A&B Ingredients, Inc.

14 Adjacent and Related Markets

15 Appendix

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The Worldwide Food Fortifying Agents Industry is Expected to Reach $128 Billion by 2027 - PR Newswire

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A Systematic Review of Nutritional Interventions on Key Cytokine Pathways in Rheumatoid Arthritis and Its Implications for Comorbid Depression: Is a…

Posted: at 6:44 pm

The inflammatory profile of rheumatoid arthritis (RA)

RA is a chronic disease characterized by the autoimmune destruction of joints and synovial tissues, which results in pain, deformity, and reduced quality of life in patients with RA[1].Because of the chronic painpatients with RA endure, the mainstay of treatment aims to reduce inflammation to both suppress symptoms and prevent further joint damage whenever possible [1]. RA is associated with both local and systemic inflammatory processes via the aberrant regulation of inflammatory pathways and imbalances in several mediators of inflammation which are looked at in detail in this study [2]. These systemic inflammatory processes link RA with other inflammatory comorbidities such as cardiovascular disease, malignancy, lung disease, osteoporosis, and neuropsychiatric diseases including depression [3-4]. Due to the expense and side effect profiles of drug regimens for pharmaceutical disease management, [1], and the increasing number of publications addressing the role of nutrition in RA treatment [1,5-6], and the correlation of RA with depression, [3,7-10], the primary objective of this review was to identify and summarize which specific dietary patterns and nutritional interventions go beyond symptom management to improve the response to known inflammatory cytokines and other inflammatory markers in the RA disease process.

Cytokines are chemical messengers in the body that are secreted by the immune system and can influence communication between cells [11]. Cytokines including tumor necrosis factor-alpha (TNF-), interleukin (IL)-1B, IL-6, IL-17, and IL-18, as well as inflammatory markers like C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) that have been used in diagnosing and tracking the progression of RA [11-12]. In many immune reactions and disease processes, TNF-, IL-6, and IL-1B increase inflammation and leukocyte recruitment, while counter-regulatory cytokines IL-4 and IL-10 decrease inflammation [11]. Dysregulation and imbalance of these systems is the mechanism behind the autoimmune dysfunction seen in RA [11]. Activated macrophages in the joint tissues of RA patients secrete various pro-inflammatory cytokines [11,13]. TNF- activates fibroblasts and IL-1B causes fibroblast proliferation [13]. This chain of reactions subsequently activates transcription factor nuclear factor-kB (NF-kB), which is one of the main inflammatory pathways seen in RA [13]. In this pathway, the receptor activator of nuclear factor kappa-B ligand (RANKL), which via increased osteoclast activity is involved in bone regeneration and remodeling, is both triggered by and produces high levels of IL-1, TNF-, and IL-6 [13]. Increased NK-kB expression also results in increased levels of metalloproteinases (MMPs), specifically MMP-2 and MMP-9, which are the enzymes responsible for breaking down cartilage in the synovial fluid of RA patients [11]. Additionally, IL-18 is found in relatively higher concentrations in the synovial tissues of RA patients, which, also via activation of NF-B, induces interferon-gamma (IFN-) production from T-cells and natural killer cells in synovial tissues [14]. Finally, studies have shown that IL-17 expression and serum concentrations of IL-6 correlate with RA clinical disease activity [15-16]. IL-17, in addition to provoking the production of pro-inflammatory cytokines IL-6 among others; also encourages Th17 immune cell differentiation, a pro-inflammatory immune pathway, which in patients with RA increases RANKL expression and subsequent osteoclastic activity [17]. In summary, the cytokine processes responsible for disease progression and inflammation in RA involve complex feedback mechanisms principally among interleukins IL-1B, IL-6, IL-17, IL-18, and TNF-, which is why this review has sought out dietary patterns and nutritional interventions that have attempted to measure impact upon these pathways.

The impact of various dietary patterns and nutritional interventions on the disease activity in RA has been investigated by several recent systematic reviews [1,5-6]. The findings from these previous publications support the link between various dietary components, inflammatory markers, and disease activity in RA [1,5-6]. For example, elimination diets, which focus on the removal of common inflammatory foods such as dairy, wheat, and refined sugars, have been shown to lower serum CRP, ESR, IL-1B, and TNF- a, while subsequent food challenges showed increasein these inflammatory markersand subsequent worsening of RA symptoms [1,5]. Other studies have shown that supplementation with high doses of polyunsaturated fatty acids (PUFAs) reduces ESR, CRP, and IL-1B levels while improving Disease Activity Score-28 (DAS-28) scores and quality of life measures in patients with RA [5,6]. Other established findings further supporting the role of dietary intervention in the management of disease in patients with RA include evidence for lowered disease activity with interventions including the Mediterranean diet, flavonoid-containing spices (ginger powder, cinnamon powder, saffron), antioxidants (quercetin and ubiquinone), and probiotics [1,6]. While previous reviews have established the important role diet plays in the management of RA, they have not focused on specific cytokine pathways, nor have they addressed inflammatory comorbid conditions like depression.

While depression is commonly found in patients who suffer from chronic illnesses, it is especially prevalent in the RA population, up to 42% [8,10]. Compared to healthy matched controls, patients with RA are more than twice as likely to develop depression[3,9]. This has important consequences for patient quality of life, as studies have shown that patients with RA and comorbid depression are more likely to be unemployed (30% versus patients with RA without depression symptoms) and that patients with RA and depression generally display higher DAS and levels of functional disability, with disability correlating to the severity of depression [8,18]. Additionally, Timonen et al. (2003) found reports of suicidal ideations in 14% of female patients with RA and 3% of male patients with RA in a prospective 13-year cohort study [19]. In patients with RA, 52.6% of suicides are by females versus 18.2% in victims who had neither RA nor osteoarthritis (OA), and the median age of completion was 61.7 years old versus 41.3 years old in victims with neither RA nor OA [19]. The pathology of depression is associated with systemic inflammation, which is a known outcome of RA and may explain this strong association [10]. Cytokines IL-6, IL-1, and TNF-, known mediators involved in the progression of RA, are strongly associated with stress-related disorders including depression and anxiety [7,10]. The presence of these cytokines is also correlated with the severity and duration of depression, marking a possible signal to the potential use of cytokines in diagnosing and following the progression of depression not only in patients with RA but also in others [10]. This is where the present review of literature postulates the potential for nutrition and dietary-based interventions playing a role in improving cytokine profiles in patients with RA not only in the hopes of improving traditional disease progression markers focused solely on the musculoskeletal system but also of improving other cytokine-mediated comorbidities, especially depression.

While various dietary patterns and nutritional interventions, as well as supplement studies, have been carried out to propose alternative treatments that might augment traditional pharmaceutical therapy for individuals with RA [5-6,20], given the importance of inflammatory cytokines on the disease progression in RA, on disabling comorbidities like depression, and on their use as biomarkers for disease activity, a new look at nutrition and diet studies was warranted with cytokines and other inflammatory markers specifically in mind. Focusing on a broader cytokine profile than those included in the commonly used DAS-28 for RA (CRP and ESR) allows for a better understanding of how nutritional interventions or dietary patterns directly influence the chronic inflammatory processes of RA. It also allows for more questions to be asked regarding the effect of such interventions on comorbid inflammatory conditions in patients with RA, which share many of the same inflammatory pathways and markers. In summary, identifying nutritional interventions and dietary patterns that improve the inflammatory cytokine profile, and therefore disease progression and inflammatory comorbidities of RA will help further focus research on treatments that may provide a better overall improvement in quality of life for RA patients by focusing on root cause inflammatory processes that affect not only joint description but also depression-rated disability.

Search Strategy

A computer-assisted systematic literature review was performed using PubMed for primary source research articles examining nutritional interventions in the cytokine profiles of patients with RA. The PubMed word search included rheumatoid arthritis and nutrition or diet and c-reactive protein or IL-1 or IL-6 or IL-17 or IL-18 or cytokines. Articles were filtered to include those published between 2016 and 2022 to improve efficacy of the review and capture the most recent and prominent research. The reference list of retrieved articles was also considered when found to be relevant and if those additional articles fit the search criteria but were not discovered through the initial search. The relevance of these articles was assessed through a hierarchical approach, with evaluation first of the title, then the abstract, followed by the full manuscript. For any articles not freely available, access was gained through the Nova Southeastern University library.

Selection Criteria

Studies were considered eligible if they examined specific nutritional interventions in the disease modification of RA and measured the interventions effect on one or multiple serum cytokines. Eligible study designs included randomized control trials (RCT), prospective and retrospective cohort studies, cross-sectional studies, case studies, and other studies on human patients and/or human cell lines. Exclusion criteria included meta-analyses, systematic reviews, editorials, non-human studies, and lack of access to the available text. A flow diagram was developed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 outline [21] (Figure 1).

A total of 236 articles were identified from the initial electronic database search. Seventy-sixarticles were excluded based on lack of relevance found during the title and abstract screening, and 18 duplicates were removed. Of the remaining 124 articles, 83 were excluded for no nutritional intervention mentioned, minimal focus on RA, ineligible study design (based on exclusion criteria), or lack of access to the full text. A total of 41 articles remained for inclusion in this review (Table 1). Most of the publications identified (35 of 41) analyzed dietary patterns or dietary supplements, and the remaining sixlooked at herbal or other supplements. None of the articles measured any improvements or worsening of symptoms of depression as a result of the studied intervention(s).

From the analyzed publications, four main overarching themes stand out: 1. Poor diet quality and/or poor adherence to anti-inflammatory diets in patients with RA results in increased inflammatory markers and pain scores [22-31]; 2. Dietary consumption of antioxidants, PUFAs, and fiber have preferable disease outcomes in patients with RA, whereas salt does not [32-38]; 3. Flavanoid supplementation, particularly with barbary extract, cinnamon, cranberry juice, curcumin, garlic, saffron, pomegranate extract, sesamin, and diindolylmethane (DIM) in patients with RA has shown promising results in reducing inflammatory cytokines active in the RA disease process [39-51]; and 4. Probiotic supplementation may be beneficial in ameliorating the profile of gut microbiota in patients with RA, also resulting in decreased disease activity [52-56].

Dietary Patterns

A significant number of the publications (26 of 41) identified focused on dietary evaluations or interventions. The studies looked at various factors like anthropometrics and diet quality, in addition to identifying various interventions analyzing the effect of fasting diets, other specific diets, and intake of salt, fiber, antioxidants, and PUFAson the inflammatory status of patients with RA. Generally, poor diet quality and diets considered inflammatory has been shown to worsen cytokine profiles and DAS [22,24-28]. Several studies in this review [24-28], found that diets defined as poor in quality (diets with low intake of fish, shellfish, whole grains, fruits, and vegetables and high intake of smoked meats and sweets), diets with higher dietary inflammatory index (DII) scores, diets with low adherence to the Anti-inflammatory Diet in Rheumatoid Arthritis (ADIRA) protocol, or diets with low adherence to the Mediterranean diet are associated with poorer outcomes including higher CRP and ESR levels and increased pain levels. Elimination diets excluding foods known to trigger inflammatory processes, for example, red meat, gluten, and dairy have also been explored as adjuvant treatment for RA patients, with one study showing a significant reduction in CRP levels, in addition to improved pain scores, lower levels of circulating leukocytes and neutrophils, and improved quality of life in patients with RA compared to controls [22].

In addition to dietary content, several other studies identified additional considerations in dietary patterns like timing and underlying anthropometrics. Intermittent fasting in the setting of diurnal fasting during Ramadan was explored as a potential method for remediating inflammation in RA in two studies [29-30]; both found improvements in inflammatory markers and pain scores during the month of fasting. One study that investigated the relationship between anthropometric measurements concluded that weight, BMI, and waist circumference were positively correlated with disease activity in RA [31]. Serum concentrations of CRP and ESR increased with increasing BMI, suggesting dietary interventions aimed solely at weight loss may positively impact disease activity and overall patient quality of life [31]. In regard to the aforementioned adipokines, ADMA, but not nesfatin-1, was associated with higher BMI and disease activity in RA patients [31].

Dietary Consumption of Salt, Antioxidants, and PUFAs

Specific dietary consumption studies included publications evaluating the effect of salt, antioxidants, fiber, and PUFAs consumption [23,32-38]. Recently, the relationship between sodium chloride (NaCl) intake and inflammation has been investigated as a potential modifier of autoimmune diseases such as RA and systemic lupus erythematosus (SLE) [33]. Studies in this review have found that synovial fluid NaCl concentration was associated with enhanced Th17 cell proliferation and resultant increases in disease activity [33] and that patients on a low sodium diet resulted in reduced Th17 cell concentrations and reductions in IL-9 and tumor growth factor beta (TGF-) after just three weeks [34].

Antioxidants play an important role in the balance between pro- and anti-inflammatory processes within the human body and are the subject of one publication in this review. Dietary recalls revealed that patients with RA generally had higher intakes of selenium and copper, and lower intakes of zinc, vitamin E, and magnesium than recommended guidelines [23]. Adequate vitamin C intake was associated with decreased IL-1, zinc intake was associated with decreased IL-2, and magnesium intake was associated with decreased levels of both IL-1 and IL-2, whereas deficient intake of vitamin E and copper were noted to decrease catalase expression, an enzyme largely involved with anti-inflammatory pathways [23].

Five of the articles in this sample discuss the role of PUFAs in reducing inflammation in patients with RA. PUFAs, primarily omega-3 long-chain fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are precursor molecules in the biosynthesis of anti-inflammatory prostaglandins and leukotrienes and act as inhibitors in the conversion of arachidonic acid to inflammatory prostaglandins and leukotrienes [63]. Omega-6 fatty acid alpha-linolenic acid (ALA) also exhibits similar anti-inflammatory activity [63]. Omega-3 supplementation has also been shown to reduce the synthesis of IL-1 and TNF- in monocytes and IL-6 in endothelial cells [64]. Additionally, higher omega-6:omega-3 ratios have been correlated with overproduction of proinflammatory cytokines [64]. Three of the five studies evaluated PUFA consumption via dietary recall [33,37-38]. The first study found that subjects who consumed fish, a food high in PUFA content, two or more times a week to have significantly lower combined DAS-28-CRP scores when compared to RA patients who ate fish never or <1 time/month, and that for each additional serving of fish per week, DAS-28-CRP was significantly reduced [38]. The second study found that diets low in omega-3 PUFAs and diets with greater omega-6:omega-3 ratios were directly associated with unacceptable and refractory pain, but not with inflammatory pain or systemic inflammation, suggesting that omega-3 PUFAs might help with pain control in RA [37]. The last PUFA dietary recall study demonstrated an inverse relationship with erythrocyte levels of the n-6 PUFA linoleic acid, specifically with risk of RA development [35].

Supplementation with PUFAs, Fiber, Flavanoids, and Probiotics

A study [43] concerning supplementation with PUFAs showed statistically significant reductions in DAS-28 scores and adiponectin levels compared to controls in the fish oil only group, and interestingly, better results when consuming fish oil supplements together with cranberry juice, resulting in further reductions in ESR, CRP, and IL-6 levels versus fish oil alone.Another PUFA supplement study with flaxseed showed improved DAS-28 scores but no changes in inflammatory markers[36].

Another dietary component under investigation for RA symptom relief is dietary fiber. Supplementation with high fiber bars developed to contain 30 grams of a combination of non-digestible soluble and insoluble carbohydrates of three or more monomeric units given daily over a 30-day period showed increased systemic short-chain fatty acid (SCFA) levels in RA patients, which are known to decrease inflammation by upregulating Treg cells, decreasing T cell proliferation, and decreasing IL-18 concentrations [32].

Flavonoids are a type of polyphenolic secondary metabolites found in plants [33]. They are widely known to exhibit powerful antioxidant, anti-inflammatory, and immunomodulatory properties [65]. Thirteen of the 41 articles analyzed involved supplement and food interventions known to be high in flavanoid concentrations. RCTsevaluating barbary extract, cinnamon, cranberry juice, garlic, saffron, pomegranate extract, sesamin, polyphenolic extract from olive oil, and DIMextract from cruciferous vegetables showed reductions in several inflammatory cytokines (see Table 1 for cytokines measured with p values) [39-51]. There were mixed results with curcumin with one RCT finding no significant improvements, while another did see decreased CRP, ERP, and other inflammatory markers in patients with RA [44-45]. Finally, no effect was seen in the RCT evaluating Brazilian propolis [40].

Five of the 41 articles analyzed involved interventions with probiotics. Patients with RA were observed to have different gut microbiomes from healthy controls [54-55]. These differences in intestinal bacteria have been shown to contribute to impaired insulin metabolism, further perpetuating inflammation and oxidative stress in patients with RA [55]. Additionally, the gut microbiota is closely linked to systemic inflammatory processes due to its manipulation of macrophage activity [66]. Regarding RA pathogenesis specifically, it is hypothesized that luminal bacterial translocation secondary to increased epithelial permeability and exposure to variable categories and amounts of bacterial antigens are potential links between gut dysbiosis and joint inflammation [28]. Two RCTs found that daily treatment with probiotics in patients with RA resulted in decreased serum hs-CRP levels and improved DAS-28 scores [55-56]. Another RCT evaluating a mixed probiotic showed improvements in inflammatory profiles with reductions in white blood cell count, TNF-, and IL-6 plasma levels, but no difference with placebo in IL-10 levels, adiponectin, CRP, ESR, ferritin, or DAS-28 [52]. Two in vitro interventions with probiotic supplementation showed inhibited levels of IL-6, IL-8, and TNF- [53] and inhibited Th17 cells and IL-17 related genes as well as several other proinflammatory mediators [54].

Of note, the Mediterranean diet, known for its balanced nutrient profile and various antioxidant and anti-inflammatory properties, has been commonly investigated regarding its impact on patients with RA [28]. In addition to demonstrating improvements in inflammatory markers and pain scores, one study in this review sought to evaluate the effect of the Mediterranean diet on the gut microbiota [28]. Their study reported significant decreases in Lactobacillaceae and Prevotella copri species in patients who were highly adherent to the Mediterranean diet, which indicated a healthier gut microbiota compositioncompared to the studys moderate/low adherence counterparts [28].

Other Interventions

Three of the 41 articles identified in this review were RCTs that evaluated the anti-inflammatory benefits of herbal supplements in patients with RA [57-59]. Supplementation with Nigella sativa extract, commonly used in Middle and far Eastern countries as botanical medicine, consumption of stachysschtschegleevii (SSC), a common herbal medicine consumed in the form of tea, and supplementation with Chinese herbal medicine Xinfeng all showed improvements inflammatory markers and DAS [57-59].

The final three studies evaluated do not fit into any of the prior intervention categories. They include human studies on Vitamin K1, n-acetyl cysteine (NAC), and silicon intake [60-62]. Vitamin K1 supplementation, compared to placebo, demonstrated no significant reduction in DAS-28 scores or serum IL-6 levels after adjusting for relevant confounders [62]. Supplementation with NAC, an important facilitator of phase 1 and phase 2 detoxification in the liver that has been shown to improve inflammation profiles, resulted in significantly lower levels of malondialdehyde, NO, and total thiol groups, but no statistically significant difference in serum IL-6, TNF-, ESR or CRP levels between the control and intervention groups [60]. Finally, silicon, which is a common food additive and also ingested from dietary sources like cereals and certain vegetables, is retained by connective tissues and has been correlated with higher collagen concentrations in the skin and cartilage, improved bone density, and some anti-inflammatory responses; however, hypercalcemia causes oxidative stress, and non-dietary sources of silicon (implants) have been found to increase the risk for autoimmune diseases in humans [61]. The study on silicon found that patients with RA, compared to healthy controls, had significantly higher serum concentrations of silicon, and exhibited a negative correlation between silicon levels and the number of swollen joints and serum IL-6 levels, however, these results were only found in females [66]. The study is overall inconclusive, noting that albumin levels, smoking status, and gender interfered with the results [61].

Final Considerations

None of the articles identified in this review measured any improvements or worsening of symptoms of depression as a result of the studied intervention(s). We propose that further studies on RA interventions should track outcomes in inflammatory and cytokine markers, and utilize validated scales and/or accepted measures of disease activity to evaluate any changes in comorbid inflammatory conditions, especially depression, to best provide comprehensive quality of life improvements for patients with RA.

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A Systematic Review of Nutritional Interventions on Key Cytokine Pathways in Rheumatoid Arthritis and Its Implications for Comorbid Depression: Is a...

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Illinois hemp farmers call market the ‘Wild West’: ‘The sky is the limit’ – Shaw Local

Posted: at 6:42 pm

Growing hemp, a plant that was illegal in the U.S. for more than 70 years, is now akin to the Wild West, two northern Illinois farmers said.

Once the 2018 federal farm bill legalized hemp, farmers across the state and country rushed to plant it. Growers were getting several hundred dollars per pound of biomass to produce cannabidiol oil, said Stacy McCaskill of Woodstock.

She and her wife run Hempstock Pharm on West South Street Road and began farming hemp in 2019.

With too many farmers planting hemp at first the market crashed and it crashed bad, McCaskill said. Overnight, it became worthless.

There are not enough processors for growers and not enough buyers for crude CBD oil, she said.

A jar of pure crude CBD oil, grown on Stacy McCaskill's Hempstock Pharm, is shown here at the McHenry County Fair on Aug. 6, 2022. The oil is added to many CBD-infused products McCaskill sells. (Janelle Walker jwalker@shawmedia.com)

Neither are there many processors turning hemp fiber into some of its uses textiles, biodegradable plastic, rope or paper Phil Montgomery of Kirkland said.

He runs AM and PM Hemp Farm with his wife, Amanda Montgomery.

Always a researcher, Montgomery said he got into hemp and CBD for the health benefits and decided to plant a few acres of hemp on their DeKalb County corn and soybean farm.

How many farmers have given hemp a try?

According to a February 2022 USDA report, in 2021 there were 255 acres of hemp planted in Illinois. Of that, 210 acres were harvested.

Across the country, 54,152 acres were planted in 2021, with 33,480 acres harvested, according to the USDA.

Some have had more success than others.

Phil Montgomery of Kirkland is one of the northern Illinois farmers who planted hemp after its legalization in 2018. Seen here at the McHenry County Fair on Aug. 6, 2022, Montgomery has left his day job off the farm to run their AM and PM Hemp Farm, making CBD-infused products. (Janelle Walker jwalker@shawmedia.com)

Since the Montgomerys planted their first 20-acre crop, Phil Montgomery has given up his day job to run their hemp business.

He hopes that Amanda also can leave her day job soon, Montgomery said.

McCaskill spends her days touting her line of CBD-infused products at county fairs, farmers markets and community festivals. On Saturdays, the Hempstock Pharm store is open at 4023 W. South Street Road.

A former executive director of the Sauk Valley Community College Small Business Development Center, McCaskill started researching how to promote and grow hemp shortly after legalization. She found workshops to learn about the plant and potential markets, becoming an evangelist for CBD and its uses.

Both Montgomery and McCaskill were selling products made from hemp grown on their farms during the McHenry County Fair.

A hemp plant in the fields at Hempstock Pharm outside of Woodstock on Aug. 6, 2022. Stacy McCaskill and family began the hemp operation in 2019 and offer CBD products made from the plants grown there. (Janelle Walker jwalker@shawmedia.com)

McCaskill has 13 acres and just one planted with hemp, entirely for the CBD oil.

Montgomery has less than three acres in CBD hemp, and 17 acres they are growing for fiber.

The sky is the limit for what hemp fiber, and future markets for it, can do, he said.

But the infrastructure is not there. That is the biggest hinderance to the fiber side, Montgomery said.

The lack of processing bottlenecked the market, Phillip Alberti said. He is researching hemp for the University of Illinois College of Agricultural, Consumer and Environmental Sciences.

That bottleneck is evidenced by the difficulty in finding companies to distill hemp biomass into crude CBD oil or process the fiber, he said.

With the glut of CBD on the market, Alberti has seen a shift from the cannabidiol hemp the plants processed as CBD oil and toward grain and fiber plants of industrial, Alberti said.

There is more research and education funneled into that avenue of production, he said.

Fiber plants can be found in ditches around the country.

Stacy McCaskill operates Hempstock Pharm outside of Woodstock and sold products made from her crop at the McHenry County Fair on Aug. 6, 2022. She has become an evangelist for the hemp plant and CBD-infused products since she began farming it in 2019. (Janelle Walker jwalker@shawmedia.com)

During World War II, the federal government allowed hemp farming to make rope. Plants escaped their fields and began to grow wild. Often called ditch weed, states have spent decades trying to eradicate the plant, although it had very low to none of the THC that gives users a high.

That is the stuff that we want to hold onto and put it in our program 70 years of natural selection and it thrived without human interaction, Alberti said.

The University of Illinois Extension service has planted variety trials to determine which plants do well here, and published a midwestern hemp database to help farmers decide which varietals to grow.

One potential use for hemp is animal feed, Alberti said.

Growers are waiting on the Food and Drug Administration to rule on whether or not that will be an allowed use, he said.

There are market estimates that suggest approval by the FDA for use as an animal feed would increase [hemps] scope by four-fold, Alberti said.

A jar of pure crude CBD oil, grown on Stacy McCaskill's Hempstock Pharm, is shown here at the McHenry County Fair on Aug. 6, 2022. The oil looks like honey, is slightly sticky, and has a smell reminiscent of its cousin, the marijuana plant. (Janelle Walker jwalker@shawmedia.com)

But still, Montgomery said, there is a lot of misinformation about hemp, CBD oil and its relation to marijuana.

Both he and McCaskill use third-party testing to ensure their CBD-only products from roll-on lotions to pet treats have 0.3% or less THC as mandated by the federal government.

When CBD products began showing up in stores, there were a lot of non-quality products out there, he said. They would claim to have CBD [in them] and dont that left a bad impression for consumers.

Because of hemps formerly illegal status, there was little research into the effectiveness of CBD oils for any ailments. FDA approval and additional research would change that, Montgomery said.

I feel this is such a new thing, and there are a ton of questions. The war on drugs skewed perceptions and left it with a ton of stigma, McCaskill said.

Fight the stigma it is about healing and a better alternative, she said.

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Cannabidiol (CBD) Skin Care Market Is Expected to Grasp the Value of USD 7583.91Million with Growing CAGR of 29.60 %: by 2029, Analyzed by Size,…

Posted: at 6:42 pm

SAN FRANCISCO, Aug. 09, 2022 (GLOBE NEWSWIRE) -- Data Bridge Market research has recently issued an inclusive industry study on Global Cannabidiol (CBD) Skin Care Market which includes growth analysis, regional marketing, challenges, opportunities, and drivers analyzed in the report. Cannabidiol (CBD) Skin Care market research reports point out that the global market is anticipated to surge at a steady rate in the coming years. This report provides a comprehensive review of the global market. Analysts have identified the key market drivers and restraints in the overall market. The historical milestones achieved by the global market and rising trends have also been studied in this Cannabidiol (CBD) Skin Care market report. Adopting such a market research report is becoming very essential for businesses as it supports better decision making, revenue generation, prioritizing market goals, and profitable business.

Global Cannabidiol (CBD) Skin Care Market was valued at USD 952.91 million in 2021 and is expected to reach USD 7583.91 million by 2029, registering a CAGR of 29.60% during the forecast period of 2022-2029.

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Summary:-

Cannabidiol (CBD) is a non-intoxicating compound, which is generally extracted from marijuana or hemp plants in the form of powder and is used for various skin care purposes. The skincare and personal care products infused with cannabidiol (CBD) possess various types of beneficial skin-soothing, relaxing, anti-anxiety, pain-relieving properties, hydrating, antioxidant and anti-inflammatory properties which aids in treating dry skin or certain inflammatory skin disorders.

Cannabidiol (CBD) skin care has largely gained popularity due to its effective usage for various skin benefits. Moreover, they are also further effective in tackling inflammation, anxiety and insomnia and also helps to improve the physiological and cognitive functions in an individual along with regulation the mood, pain and memory. Cannabidiol (CBD) is one of 113 identified cannabinoids in cannabis plants and accounts for up to 40% of the plant's extract. As a result, its increased popularity regarding its benefits is projected to aid the market growth over forecast period.

Some of the major players operating in the cannabidiol (CBD) skin care market are

The unprecedented health and economic crisis created by the COVID-19 pandemic has severely impacted industrial activities. Businesses have either been forced to shut down or are experiencing massive revenue losses. To enable your business to survive these trying times, Data Bridge Market research offers comprehensive Global Cannabidiol (CBD) Skin Care Market research report based on our experience and expertise. These reports contain a detailed impact analysis of the coronavirus pandemic on the market of your concern.

Recent Development

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Opportunities for Players

Furthermore, the increasing number of technological advancements driven with a view to minimize the production costs coupled with the developmental operations directed towards sustainable development to ensure optimum and judicious use of resources generate lucrative opportunities to the market players in the forecast period of 2022 to 2029.

The surging funding from federal government pertaining to the research and development proficiencies are projected to expand the future growth of the cannabidiol (CBD) skin care market. Moreover, the various research and development (R & R&D) activities aimed at lowering THC content and a growing emphasis on obtaining faster regulatory approval will positively influence market growth.

How the Report Aids Your Business Decision?

Key Drivers

The cannabidiol skin care is becoming increasingly popular across the globe, owing to the increased awareness about the benefits of cannabidiol and its medicinal properties. Moreover, the increasing adoption of CBD skin care products as it possess antioxidant properties counteracting the signs of aging boosts the overall demand for the .

Furthermore, the factors such as surge in public-private funding for targeted research activities, high disposable income, rapid urbanization, changing lifestyles, and rising product innovations and development due to technological advancements worldwide boost the market value. Moreover, increased internet penetration, continued product development and commercialization, government supportive regulations for the use of cannabis-related products, particularly in developing nations, and rising per capita expenditure will all contribute to the market's future growth rate.

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Regional Analysis-

The countries covered in the cannabidiol (CBD) skin care market report are U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, Israel, Egypt, South Africa, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.

North America dominates the market in terms of market share and market revenue and will continue to flourish its dominance during the forecast period of 2022-2029. The market growth over this region is attributed to the legalization of marijuana in Canada and U.S and the presence of large number of key players within the region.

On the other hand, Asia-Pacific is estimated to show lucrative growth over the forecast period of 2022-2029, due to the rising awareness about the benefits of cannabidiol-infused beauty products within this region.

TABLE OF CONTENTS

Part 01: Executive Summary

Part 02: Scope Of The Report

Part 03: Research Methodology

Part 04: Market Landscape

Part 05: Pipeline Analysis

Part 06: Market Sizing

Part 07: Five Forces Analysis

Part 08: Market Segmentation

Part 09: Customer Landscape

Part 10: Regional Landscape

Part 11: Decision Framework

Part 12: Drivers And Challenges

Part 13: Market Trends

Part 14: Vendor Landscape

Part 15: Vendor Analysis

Part 16: Appendix

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Cannabidiol (CBD) Skin Care Market Is Expected to Grasp the Value of USD 7583.91Million with Growing CAGR of 29.60 %: by 2029, Analyzed by Size,...

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Anti-Aging Conference and Olympia Weekend Set for Back-to-Back Weekends in Vegas – Muscle & Fitness

Posted: at 6:41 pm

The world of science and anti-aging continues to align with the world of bodybuilding and overall fitness, a reality that will be on full display during a unique scheduling phenomenon this December in Las Vegas.

The people and companies that make up the world of bodybuilding have a mission to help build a better body and improve the quality of life for those that support it. The anti-aging movement has committed decades to helping folks maximize the quality and quantity of life by providing solutions and strategies to slow down the aging process so people live better, longer.

When Joe and Ben Weider began their fitness crusade in the 1940s, they werent only thinking about building muscles and being strong in their 20s and 30s, they were working to create a movement that could serve people and help them enhance their fitness and wellness as they aged. It wasnt only looking better; it was about living a better and longer life well into the later years.

Joining them for a long portion of this movement is a man that has worked to carry it forward well into the 21st century. Dr. Robert Goldman is known within fitness circles for several reasons. Hes a sixth-degree black belt, set over 20 world records for various physical feats of endurance and strength listed numerous times in the Guinness Book of World Records, hes worked alongside the IFBB & NPC as the Chief Medical Advisor and Chairman of the IFBB/NPC Medical Committee overseeing the over 190 nations of the federation, he created the first personal trainer certification through founding the National Academy of Sports Medicina (NASM), and hes the founder of the International Sports Hall of Fame. Goldman can also be considered the godfather of the anti-aging movement. In the late 1980s and early 1990s, a time that the phrase anti-aging was used as a marketing tool to promote cosmetic products, Goldman was laying the groundwork for change. Part of that groundwork included developing the American Academy of Anti-Aging Medicine (A4M) Conference World Congresses as well as the website worldhealth.net, the second medical website in existence and the go-to source for anti-aging and life extension information.

The American Medical Association beat us online by 30 days, Goldman said. We have decades and tens of thousands of medical articles and even videos by Nobel laureates whom have lectured over the past 30 years. Many of them have since died, and that massive archive of information for consumption. People can self-educate, print these articles, then go to their doctors about whatever their concern is.

Many people in the anti-aging community look at Goldman the same way that many longtime bodybuilding fans see Joe Weider. In what is the first of several common threads between the two industries, Goldman credits that success to his background working under the tutelage of the Weiders.

Bodybuilding actually had a part in that because it came from me serving under Ben and Joe. I got introduced to many Ministers of Health and Ministers of Sport in numerous countries. Bodybuilding gave me the wherewithal to form national and international governing bodies. So, what they were doing for bodybuilding, I was doing by setting up anti-aging conferences around the world.

The first A4M conference was held in 1992 with 12 doctors getting involved a far cry from the over 100 that are expected to speak and over 6,000 expected at the 30th Annual World Congress on Antiaging & Regenerative Medicine. Goldman described the mission as teaching the teachers. The doctors and experts that come in give their lectures to the doctors that will go home and serve their patients directly with the goal of promoting natural and healthy solutions that could serve as life extension. A4M has held multiple conferences around the world every year, having trained over 150,000 doctors to better serve their patients.

Just like the Weider brothers had to face challenges throughout their journey in fitness, Goldman & his A4M CoFounder, Dr. Ronald Klatz, and their allies had to face obstacles created both outside and inside the medical community. As far as the establishment at the time was concerned, this movement should have never happened to begin with.

The goal was to destroy it, not unlike what the fitness industry went through when gyms were being told to close, and they as the old-world medical establishment were trying to stunt the growth of the sports nutrition industry, he suggested. They would rather have people taking prescription drugs instead of focusing on exercise, nutrition, and other natural solutions. The goal was to diminish and shut down natural forms of medicine such as homeopathy, wholistic nutrition, etc. They wanted to destroy that.

Goldman said that the doctors and advocates for anti-aging were fighting an uphill battle in the early years because of hypocrisy and greed and control. They would even go as far as offer support to advertisers and the media that would be considered counterproductive.

Believe it or not, the goal was to also support cigarette companies. There would even be full page ads in the medical journals like the Journal of the American Medical Association with doctors smoking cigarettes. This is similar to when research was coming out showing that a healthy diet and exercise could diminish the risk of heart disease in the 1960s. They were shutting down gyms in California, and they even went after the Weiders at that time.

Dr. Klatz was one of Goldmans allies in the beginning, and hes as involved now as hes ever been. He recalled how the movement originally started in 1991, while they were both working in sports medicine.

We had come to a barrier that was beyond elite sports nutrition, and that was long-term healthcare. It wasnt just about improving performance for your sport, but it was about improving performance in later years, and ultimately, your lifespan, he said. It required a change in the paradigm of healthcare because healthcare wasnt healthcare back then. It was disease maintenance. The established belief of medicine at the time was that aging was inevitable, and nothing can be done about it.

In spite of the challenges and struggles they faced from opposition year in and year out, the A4M and their movement has not only survived they have thrived. According to Goldman, the anti-aging industry is now a $260 billion (yes, with a b) movement, and its growing at a rapid pace. The 2022 A4M conference will be their 30th anniversary. They are now the biggest event for the healthcare, medical, and wellness professionals in the field. For the medical and anti-aging movement, A4M has become appointment traveling.

We have over 100 world-class people speaking at our conference, and these people could book their own seminars alone and people would pay to come see just one of them. Now consider that there are dozens and dozens of sessions that they can choose from every day.

Dr. Klatz agrees with Goldman, and he feels that if there was ever a year to attend a conference of this magnitude, the 2022 conference is it.

Were really living in unprecedented times with regard to Covid, even long Covid, and long-term health challenges, said Klatz. A lot of people are feeling them, and a lot more are going to be feeling them. So, the more youre involved in healthcare, and the more you focus on your metabolism and your future health, the greater chance you have of survival.

Similarly, the marquee brand for the world of bodybuilding and fitness enthusiasts is the Joe Weider Olympia Fitness and Performance Weekend. The movement that began with Larry Scott being crowned the first Mr. Olympia in 1965 has also become a billion-dollar movement. Olympia owner Jake Wood and president Dan Solomon will lead their team and host the Olympia in Las Vegas for the first time since 2019. Fans from across the globe gather to get a taste of the industry they love and watch the champions they admire compete for glory and legacy. Wood and Solomon are carrying the mission that the Weiders created so a whole new generation can focus on fitness and enhance their quality of life. Goldman expressed appreciation for their efforts. He hopes that the people that attend A4M will notice as well.

Under the leadership of Jake and Dan and their ancillary partners, we can open up a whole new world that would be beneficial to both communities with a more synergistic, positive outcome.

Both A4M and the Olympia have their differences, but their missions are quite similar help people live longer and better. These two powerhouse events have been making their own differences and seen tremendous success over the years. However, 2022 will mark a transformational year because it will be the first time that both the A4M and the Olympia will be held on back-to-back weekends in the same venue.

Olympia President Dan Solomon adds, The opportunity to attend the A4M Conference and the Olympia in back-to-back weekends will be a powerful experience. Those who take advantage of this opportunity will leave Las Vegas with enough inspiration and education to fuel an entire year of transformational education and inspiration.

The Olympia will be taking place in Las Vegas on the weekend of December 15th through 18th. One week before that, the A4M conference will be held from December 8th through 11th. Coincidentally, both events will even be in the same building the Venetian Resort. The A4M conference will cover over 500,000 square feet and feature world-class speakers offer their guidance that can provide value to the listeners long after they go home and a massive Expo of hundreds of medical health companies. Sports legends and Hollywood movie stars have attended A4M and express wishes to return. In Goldmans opinion, Olympia fans would be well served booking that flight and hotel one week in advance and attend A4M.

The exhibits will feature booths that focus more on anti-aging and longevity. The companies that will be there would greatly benefit fitness minded people, he shared. More importantly, there will be thousands of doctors from anywhere from 30 to 60 countries to present and learn from each other. It will be unlike any educational opportunity they have ever experienced.

This is very important because experts and insiders on both sides of the fence have expressed concerns about athletes experiencing health issues, or worse, at a young age. The people that are interested in the Olympia could benefit from learning more and applying strategies that they can hear about directly from doctors that they otherwise may not get to speak with, so they can learn and apply information they otherwise may not get. As far as Goldman is concerned, this is a great opportunity to potentially save lives.

You know the challenges weve had in bodybuilding and other communities, with athletes not faring well, health wise some even dying. So, its time for us to circle the wagons and utilize the medical technology and information that is available to protect the community.

The two events being so close together can serve as a landmark opportunity for businesses that considers health and fitness a priority as well. Doctors and trainers and gym owners can discuss how to join forces with the goal of serving clients and patients in a coordinated fashion. In Goldmans eyes, this is a rare moment that needs to be taken advantage of. It should also be a call to action.

This is a historical situation with both of these world class events being in the same city, same venue, and even the same exhibit hall, said Goldman. These are different, intertwining industries, and it is now time for them to cooperate with each other. Trainers can interface with doctors, and doctors can talk to people that run the gyms and spas, which could help improve career opportunities and create a synergy.

One of those trainers that sees the opportunity available is Rob Fletcher, founder of Americas Next Great Trainer. Fletcher and Goldman had worked together for years with hopes of having trainers and physicians work side by side.

This is a huge step for all. For years Dr, Bob and I had conversations about bringing the worlds together bodybuilding, sports, health, fitness, and anti-aging. There is tremendous value and benefits on so many levels, Fletcher said. It is the ultimate strategic partnership or marriage bringing physicians, athletes, trainers, and gym owners together to educate and raise awareness for optimal health and performance.

Because of his background in bodybuilding, Goldman and the team that run A4M understands how they can benefit from the Olympia as well. He suggested that the exhibitors that present at their conference should consider hanging around for another weekend to reach a new massive market of consumers they may not be able to reach otherwise.

If I was a doctor and I wanted to integrate sports medicine, health related patients of all ages, and not (even) only competitors but 60-70% of the people there or more dont compete. Right in front of them would be tens of thousands of potential patients at the Olympia. They will be rolling around Las Vegas that weekend like these world-class doctors will at A4M, he noted. Why not stay around an extra few days and have my services offered to a whole new consumer base?

Likewise, thousands of people will gather in Las Vegas for the Olympia, and many of them may have questions about their own health and wellness situations. This has never been truer than two years after the onset of the pandemic. What better place could they learn more about what to do and how to do it than the place where the best minds in medicine will gather as well? Goldman is extending the olive branch and wants to invite his fellow fitness community members to join him.

They will learn more at this years A4M conference than if you were to go to 20 other conferences. The doctors at A4M hope they will come because they would like to meet these potential patients and offer their services.

For more information about A4M and make arrangements to attend, go to http://www.a4m.com and http://www.Worldhealth.net. For more information about the Olympia Weekend, go to http://www.mrolympia.com.

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Anti-Aging Conference and Olympia Weekend Set for Back-to-Back Weekends in Vegas - Muscle & Fitness

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A son steps aboard the Eagle and into his father’s world – Journal Inquirer

Posted: at 6:41 pm

NEW LONDON When he was a boy, Jeffrey Glowski said he built a toy model of the ship his father sailed across the Atlantic Ocean.

Now, 76 years after the Coast Guard barque Eagle first arrived in New London, Glowski was aboard the ship he previously had never seen in person.

It was just a little sentimental, really, Glowski said of the experience. Amazing.

Glowskis father, Jerome Glowski, was a member of the original commissioning crew that pieced Eagle back together in the aftermath of World War II in Bremerhaven, Germany. Jerome had been stationed in Newfoundland for most of the war on submarine duty, Jeffrey said, but was one of the few who flew to Germany with Cmdr. Gordon McGowan to claim the USCGs war prize, named Horst Wessel at the time, while the allies divvied up the remnants of the German fleet.

Glowski, 72, said his father, a radio operator aboard Eagle, didnt tell too many stories of the maiden voyage nor of the crew pieced together of Coast Guardsmen, former German crewmen and some borrowed German ex-navy volunteers from a British minesweeping project.

He talked about the hurricane, Glowski said of his late father. That was a scary time going through that. Not much more.

McGowan and his crew were a day or so away from their destination when they found themselves in the middle of a hurricane that ripped apart Eagles sails and caused an estimated $20,000 in damages. Glowski detailed how he too had been sailing once when confronted by a storm that packed 70 knot winds with main sails in the water and the boat on its side.

That was scary, he said.

He much preferred to re-enact the other parts of his fathers tenure on Eagle, like visiting the same radio room his father had many years back.

Glowski, led by Eagles Sail Master, Chief Warrant Officer Melissa Polson, toured all 295 feet of the tall ship. While the radio control room was at the top of the list, Glowski saw it all. The tour made stops in the captains quarters, the mess deck, the sleeping quarters. From the ships bow to its stern, Glowski took every step, and a few photos for keepsakes.

I just cant imagine back then, Glowski said, looking at a photo of Coast Guardsmen resting in hammocks to accommodate the tight space.

Nowadays, for the Coast Guards training ship, there are rows of bunk beds.

While modern amenities, like electronics, cooking equipment and laundry machines, have made their way to Eagle, the majority of the ship is original. Polson explained how parts of the hull had to be replaced and the main decking was redone in the 1980s, but the majority of the hull, the fittings and structures, and the main mast, are all original.

In 2014 through 2018, Eagle underwent a Service Life Extension Project to address the ships longevity, and will do so again in 2028 to address concerns for the following 15-20 years.

This winter, the ship will dry dock for a mast overhaul, Polson said. She explained the foremast, the running rigging, the standing rigging, blocks, lines, sails and yards will all come off and be re-overhauled before she sets sail again.

Before Glowski set sail back home to Indiana, where he grew up with his two brothers, he gifted Polson a photo of his father, sitting in Germany with Eagle in the distance. It was placed in front of a photo Polson said she shows all guests, one of Eagle in its dilapidated state in Germany, nearly identical to Glowskis photo.

Across the room hung a painting of Eagle commissioned by the son of the ships original captain. Polson said Glowskis father likely sailed across the ocean with the painter aboard the ship.

Just such a unique collaboration of ... Polson said, her thoughts drifting.

...history, Glowski finished.

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A son steps aboard the Eagle and into his father's world - Journal Inquirer

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Class to teach healthy living for those with chronic conditions – The Maryville Forum

Posted: at 6:41 pm

MARYVILLE, Mo. Living a Healthy Life with Chronic Conditions, a program that will discuss strategies for daily management of any chronic condition, will run from Aug. 24 through Sept. 28 at the Maryville Public Library, according to a news release.

An evidence-based program, Living a Healthy Life with Chronic Conditions consists of six, two-and-a-half hour classes that will be held on Wednesdays from 2 to 4:30 p.m.

The free classes are open to anyone who deals with a chronic condition or is a caregiver for someone with a chronic condition.

According to a press release, topics covered will include weekly action planning and problem solving; techniques to deal with frustration, fatigue, pain and isolation; appropriate use of medications; nutrition; appropriate exercise for maintaining and improving strength, flexibility and endurance; communicating effectively with family, friends and health professionals; how to evaluate new treatments and more.

Each participant will receive the Living a Healthy Life with Chronic Conditions book and a Relaxation for Body & Mind CD.

Classes will be co-taught by University of Missouri Extension Nutrition and Health Education Specialist Debbie Bennett and Vickie Kempf from Mosaic Medical Center - St. Joseph.

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New application for disinfection of fresh-cut fruits by means ozone in the packaging – hortidaily.com

Posted: at 6:41 pm

PerfoTec is delighted to announce a new innovation partnership with Blue Skies to develop an new -safe and natural- application for disinfection of fresh-cut fruits by means of active oxygen (ozone) in the packaging.

Blue Skies is searching for an application to kill micro-organisms to extend the freshness of Fresh-cut Fruits in a natural and safe way, without changing the quality and appearance of packed fruit. PerfoTec and Blue Skies are joining forces to finalize the development of this technology, calledPerfoTec O3Control, to add a specific dose of ozone safely into the topseal packs to kill bacteria, yeast, and mould spores whilst optimising the protective atmosphere. Since 2004 PerfoTec has developed several practical tools to extend the freshness of Fresh Produce, and the development of this new technology fits well within PerfoTecs mission. Both PerfoTec and Blue Skies are aiming to finalize this new technology for validation and optimization in a real production environment during 2022/23.

PerfoTecs mission is to combat the waste of fresh vegetables, fruits and flowers by applying the best possible protective atmosphere inside the packaging. This Dutch-based post-harvest company is the worlds leader in this field, and works together with many companies and customers around the world to improve the freshness of their products. Together with the clients quality teams, PerfoTec creates the optimal solution for the fresh produce packaging in a natural way. When the ideal atmosphere is reached in the pack, the freshness will be extended to the maximum, both for retail and bulk packaging. PerfoTecs technology can be integrated onto every new or existing packaging line, from topseal packaging machines, vertical packaging machines to flowpack machines.

Founded in 1997, Blue Skies, is a world leader in Fresh-cut Fruits, and, unlike many other companies looks to add value at the source. This means that Blue Skies produces the finished product where the fruit is grown. The approach is simple: fruit will be harvested only when fully mature, cut when naturally ripe and delivered fresh from harvest. Blue Skies collaborate with PerfoTec in two areas: One is the extension of life for fruits that they store at their factories in Africa and the other is extension of life for finished prepared fruit products that they send to European retailers. Both of these areas are critical to reduce food waste and increase food production and distribution sustainability. Extension of the time for which Blue Skies can store fruits that they use at their factory in Ghana by clever manipulation of gas concentrations reduces the amount that they send to their compost site before processing. Additionally, this approach increases the quantities that Blue Skies can use from West African sources so that they do not need to import expensive fruits from Brazil and South Africa that take a long time to reach Ghana and have lower yield figures when processed.

This new technology can become a game-changer for the fresh-cut fruit industry, initially for the UK and North America. The partnership between our two companies is an exciting opportunity and we are thrilled to be working with Blue Skies, a business closely aligned with our own ambition to provide science-led shelf-life extension solutions to the market, according to PerfoTecs Founder and CEO, Bas Groeneweg.

Blue Skies CEO, Hugh Pile, adds : Use of ozone as a sanitising agent for finished products may improve food safety and extend the time that the product remains visually acceptable to the consumer thus reducing waste at the point of sale. This has long been a holy grail in the industry and PerfoTec have developed a system that permits this use of ozone gas in a populated environment.

Once the new PerfoTec technology will be successfully operational within Blue Skies, after an initial optimization period, other customers will be welcomed so they can enjoy the benefits as well.

For more information:Bas GroenewegPerfoTecKlompenmakersweg 163449 JB Woerden+31 (0)297 25 55 54info@perfotec.comwww.perfotec.com

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New application for disinfection of fresh-cut fruits by means ozone in the packaging - hortidaily.com

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