Daily Archives: February 24, 2022

Got a Covid Booster? You Probably Wont Need Another for a Long Time – The New York Times

Posted: February 24, 2022 at 2:35 am

Researchers showed last year that the elite school inside of lymph nodes where the B cells train, called the germinal center, remains active for at least 15 weeks after the second dose of a Covid vaccine. In an updated study published in the journal Nature, the same team showed that six months after vaccination, memory B cells continue to mature, and the antibodies they produce keep gaining the ability to recognize new variants.

Those antibodies at six months are better binders and more potent neutralizers than the ones that are produced one month after immunization, said Ali Ellebedy, an immunologist at Washington University in St. Louis who led the study.

In the newest study, another team showed that a third shot creates an even richer pool of B cells than the second shot did, and the antibodies they produce recognize a broader range of variants. In laboratory experiments, these antibodies were able to fend off the Beta, Delta and Omicron variants. In fact, more than half of the antibodies seen one month after a third dose were able to neutralize Omicron, even though the vaccine was not designed for that variant, the study found.

If youve had a third dose, youre going to have a rapid response thats going to have quite a bit of specificity for Omicron, which explains why people that have had a third dose do so much better, said Michel Nussenzweig, an immunologist at Rockefeller University who led the study.

Memory cells produced after infection with the coronavirus, rather than by the vaccines, seem less potent against the Omicron variant, according to a study published last month in Nature Medicine. Immunity generated by infection varies quite a lot, while the vaccine response is much more consistently good, said Marcus Buggert, an immunologist at the Karolinska Institute in Sweden who led the study.

Although most people, vaccinated or not, show only a small drop in their T cell response against Omicron, about one in five had significant reductions of their responses of about 60 percent, Dr. Buggert said. The differences are most likely because of their underlying genetic makeup, he said.

Still, the recent studies suggest that in most people, the immunity gained from infection or vaccination will hold up for a long while. Even if mutations in new variants change some of the viral regions that T cells recognize, there would still be enough others to maintain a reasonably strong immune response, experts said.

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Got a Covid Booster? You Probably Wont Need Another for a Long Time - The New York Times

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Queen Elizabeth Tests Positive for Covid-19, as England Moves to Relax Rules – The New York Times

Posted: at 2:35 am

Queen Elizabeth II has been infected with the coronavirus, Buckingham Palace said on Sunday, becoming one of the worlds most prominent figures to battle the virus and deeply rattling the country she has led for seven decades.

The palace issued few details about the condition of the queen, who turns 96 in April. She is one of several people at Windsor Castle who are infected, a palace official said, suggesting an outbreak at the royal residence, west of London, where the queen has spent most of her time since the pandemic engulfed Britain in March 2020.

Buckingham Palace confirm that the queen has today tested positive for Covid, the palace said in a statement. Her Majesty is experiencing mild coldlike symptoms but expects to continue light duties at Windsor over the coming week. She will continue to receive medical attention and will follow all the appropriate guidelines.

Elizabeth met earlier this month with her eldest son and heir, Prince Charles, who was later reported to be reinfected with the coronavirus and went into isolation. He last contracted a mild case of the virus in March 2020. The palace on Sunday did not address whether Charles was the source, but officials pointed to the number of cases at Windsor Castle, suggesting she could have been infected by others in the royal household.

The news of the queens illness came as Prime Minister Boris Johnson was poised to relax the remainder of coronavirus restrictions in England, including a requirement to isolate for five days after receiving a positive test. Mr. Johnson will introduce plans on Monday to lift the regulations by the end of February, prompting some members of the opposition Labour Party to warn that he was acting rashly.

Britain reported 25,696 new cases on Sunday, accelerating a decline since the latest wave of the virus peaked in early January with more than 200,000 cases a day. Nearly 1,300 people were admitted to hospitals and 74 people died statistics that are also on the decline, but at a more moderate pace than cases.

Now is the moment for everybody to get their confidence back, Mr. Johnson told the BBCs Sunday Morning show, before the queens condition was made public. Hours later, on Twitter, the prime minister said he wished Her Majesty The Queen a swift recovery from Covid and a rapid return to vibrant good health one of a flood of well wishes from across Britain and around the world.

Britons have no shortage of experience with prominent public figures contracting Covid. In addition to Charles, 73, his wife, Camilla, tested positive four days after he did. His elder son, Prince William, had the virus in early 2020, disclosing it only months later. Mr. Johnson suffered a severe bout of Covid around the same time and ended up in an intensive care unit.

Still, even that alarming episode paled next to news that the queen, who recently marked her 70th anniversary on the throne and has reigned for longer than most Britons have been alive, had contracted a potentially deadly disease.

It comes on top of other health concerns about Elizabeth. In October, she canceled multiple public appearances, including a solemn anniversary to honor Britains wartime dead. She also has stiffness in her legs and has begun using a walking stick.

Last Wednesday, she appeared fragile at an audience with two senior military officers at Windsor Castle. When they asked how she was, the queen, smiling and clutching the stick, gestured to her legs, and said, Well, as you see, I cant move. Neither the queen nor her guests were wearing face masks.

Until recently, Buckingham Palace had gone to extraordinary lengths to protect the queen from exposure to the virus. She retreated to Windsor in early 2020 with her husband, Prince Philip, and lived in virtual quarantine for more than a year. When she addressed the nation during a particularly dark period, in April 2020, she recorded the speech with only a single camera operator in the room.

Elizabeth received a dose of a coronavirus vaccine in January 2021 at Windsor Castle, along with Philip. The palace has not confirmed any subsequent vaccine doses, but she is widely believed to have received two, as well as a booster. Charles and Camilla have confirmed they are fully vaccinated and boosted.

Buckingham Palace has been extremely circumspect with details about the queens health. In October, the palace confirmed that she had been admitted to a hospital for tests only after a London tabloid reported it. It did not say whether she had been tested for the virus after Charles was reinfected this month.

Philip died last April at age 99, and the queen was forced to isolate herself during his funeral service. A photographer captured a poignant image of her, grieving alone and wearing a mask, in a choir stall at St. Georges Chapel at Windsor.

That image has taken on political resonance in recent weeks, as Mr. Johnson has battled a scandal over parties held in Downing Street that violated lockdown restrictions. Two of the gatherings were on the evening before Philips funeral, prompting Mr. Johnson to apologize to the queen.

The circumstances of the queens infection remained wreathed in questions. Charles was at Windsor Castle on Feb. 8 for an investiture ceremony. He got the news that he had tested positive on Feb. 10 and postponed a trip to Winchester, England, at the last minute.

There were similar concerns about the potential exposure of the queen the first time Charles was infected. The princes royal household confirmed his positive test on March 25, 2020. He had met his mother on March 12, only a day before his doctors assessed he could have been infectious. A spokesman for the prince said on Sunday that he did not plan to issue a statement on the queens condition.

Given the transmissibility of the Omicron variant of the coronavirus, which is the dominant variant in Britain, public health experts said the queen could have picked it up from anyone. In addition to the military officers, she played host to other visitors, including a group on Feb. 5 that helped mark the 70th anniversary of her accession to the throne.

Omicron is incredibly infectious possibly the most infectious disease in recent human history and its therefore unsurprising the queen has also tested positive, said Devi Sridhar, the head of the global public health program at the University of Edinburgh. The queens advanced age, she said, was an added challenge.

Buckingham Palace tried to ease concerns about Elizabeth by issuing a congratulatory message from her to Britains womens curling team, which won a gold medal at the Winter Olympic Games in Beijing.

I know that your local communities and people throughout the United Kingdom will join me in sending our good wishes to you, your coaches, and the friends and family who have supported you in your great success, she said.

A palace official said she had signed off on the statement on Sunday morning, before her condition was made public.

In recent weeks, Elizabeth seemed to be moving on multiple fronts to settle the royal familys business. Last week, her second son, Prince Andrew, reached an out-of-court settlement of a sexual assault case filed against him by Virginia Giuffre, who accused him of raping her when she was a teenager.

The settlement spares the royal family the prospect of Andrew having to testify under oath about his contacts with Ms. Giuffre, which would have cast a long shadow over the queens Platinum Jubilee celebrations in June.

On the weekend she marked her accession, the queen said in a statement that she hoped that when Charles succeeded her, Camilla would be known as queen consort an endorsement that the couple had long sought.

We are deeply conscious of the honor represented by my mothers wish, Charles said in a statement. As we have sought together to serve and support Her Majesty and the people of our communities, my darling wife has been my own steadfast support throughout.

On a blustery, rainy day in London on Sunday, people expressed anxiety about the queen, mixed with hope that she would get first-rate medical care. Above all, it seemed to drive home the reality that the coronavirus spares nobody.

It doesnt have boundaries, said Hussein Ahmed, 34, who was waiting for a bus in North London. It does not give a damn about whether you are the queen or a king or a normal civilian, a person in high power you are getting it.

Stephen Castle and Megan Specia contributed reporting.

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One of the most deadly waves | Coronavirus Updates Newsletter – The Philadelphia Inquirer

Posted: at 2:35 am

The gist: The omicron variant is continuing to subside, but its surge was one of the deadliest waves weve seen in Pennsylvania. Meanwhile, Philadelphias promise of $100 for folks who get vaccinated now isnt drawing big crowds, and Pennsylvania schools have likewise been slow to take up a free testing program offered by the state. Vaccines, meanwhile, remain an important tool in fighting the pandemic and they may also help combat long-haul COVID-19, a study has found.

Tell us: Phillys offering $100 for people who get vaccinated. What do you think could encourage vaccinations? Send us a note, and well share some responses in next weeks newsletter. Please keep it to 35 words.

Sign up for News Alerts: Be the first to know whats happening in Philly with our free service delivering timely emails about developing stories right to your inbox.

Nick Vadala (@njvadala, health@inquirer.com)

Despite it being less likely to cause severe illness and death than previous COVID-19 strains, deaths from the highly transmissible omicron variant were still high due to the sheer number of people infected during the latest surge. As a result, more than 9,000 Pennsylvanians have died from COVID-19 since Dec. 1, giving the state one of the nations highest per-capita death rates in what has been called one of the most deadly waves weve seen.

Hospitals throughout Pennsylvania and New Jersey are reporting dramatic drops in COVID-19 patients as the omicron surge continues to subside.

A promise of $100 for people getting vaccinated against COVID-19 hasnt brought big crowds to Philadelphias clinics at least not yet.

Despite spikes in coronavirus infections and low child vaccination rates, schools across Pennsylvania have been slow to enroll in a free testing program.

Long-haul COVID-19, often shortened to long COVID, is less common among people who were vaccinated, a review of multiple studies has found.

Philly-area schools are increasingly ending mask mandates, but how and when theyre deciding to do so is dividing communities.

Delco is the most populous Pennsylvania county without a health department. It is, however, getting one very soon, officials say.

Some Philly restaurant owners are choosing to keep requiring proof of vaccination.

Penn States THON, a 46-hour dance marathon, returned for its 50th year with new safety protocols.

Phillys health department clowned rapper Nicky Minaj over a controversial COVID-19 comment, and a Twitter storm erupted.

Coronavirus cases and hospitalizations are declining in Pennsylvania and New Jersey. Track the latest data here.

Last week, we asked what you think about the vaccine mandate for indoor dining ending. Heres what you told us:

Back to cooking at home. Close quarters, everyone unmasked, everyone speaking up because restaurants are loud; Im not going to be comfortable eating out anymore.

To me, this seems like a cheap campaign move and further erodes the public trust in the health department and city council. Such a disappointment.

Youre forcing maskless conscientious people to sit amongst a crowd of irresponsible unvaccinated people. No thank you, I opt for Jersey Mikes takeout subs.

Glad to see the vaccine mandate go! Doubt it did any good but scare off some restaurant goers like myself who chose to eat outside the city during this time. Hope this provides some relief to restaurant owners and workers!

This is a great way for the city to make even more spaces inaccessible for vulnerable people.

Its not over yet. People concerned about the economy always take steps too quickly and that doesnt work. A few more weeks could make a difference in the return back to normal.

This move may placate the unvaccinated, but it will take away the pleasure and possibly the safety of indoor dining for many.

Presales for the Franklin Institutes highly anticipated Harry Potter exhibition eclipsed presales for all other shows at the museum since 2007. But is it, you know, any good? We took a young Harry Potter fan to check it out and get the skinny on this massive, 20,000-square-foot show. From boggarts to Quidditch, heres what you have to look forward to.

Birria tacos are big right now, and Philly has plenty of meaty, crispy options on offer to satiate all your savory cravings but here are the real standouts.

Burned out on your day-to-day corporate grind? Do like this Fishtown woman did and give it all up to make handheld fishing nets prized by fly fishermen around the world.

Philly (understandably) still has James Harden fever, so here are 13 things you need to know about the newest Sixer.

The social isolation the pandemic has caused is tough, but this group of friends has a unique remedy: Dominoes. Spread across Philly, New York City, New Jersey, and Virginia, they meet twice a week nearly every week for two years now on Zoom to catch up and play a game of bones. Their name? The DominOsos, which loosely translates as the dominos playing bears.

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Op-Ed: Omicron won’t be the last coronavirus variant to haunt us – Los Angeles Times

Posted: at 2:35 am

Think back to late June 2021, when there was containment of the American COVID-19 pandemic with fewer than 12,000 new cases a day and a total of 15,000 patients in the hospital. There was a declaration of independence from the virus on July 4, just as the Delta variant was starting its exponential growth. A major surge ensued, which was followed by yet another one with the Omicron variant, peaking with nearly 160,000 people hospitalized and almost 2,700 deaths per day the most deaths since vaccinations became widely available.

Even now, as we are descending from the Omicron wave, we still have more than 60,000 patients in the hospital and more than 2,000 deaths per day.

The SARS-CoV-2 virus is still with us and is adroit at finding new ways to infect us at scale. As it evolved from the original strain in late 2019, and progressed to the Alpha and Delta variants, it became more virulent and infectious, not less. There is a misconception that the virus is destined to evolve to a more benign form. If weve learned anything from the pandemic, its that the virus has an extraordinary ability to adapt and it is unpredictable.

You can just look at the more than 50 new mutations present in Omicron to know there are seemingly infinite ways for it to further mutate and rearrange the 30,000 base pairs in its genome. Although wed be fortunate for it to morph into a common cold coronavirus cousin, we certainly cant count on that. There are just too many vulnerable hosts out there for more evolution of the virus to take place, including a wide variety of animals, with potential to spill over to humans.

There are more than 7 million Americans who are immunocompromised, who are not only highly vulnerable to infections, but also may provide an opportunity for the virus to evolve inside a person and then infect others. That path may indeed be the way Omicron was created and spread.

Around the world, there are billions of people unvaccinated and likely without any protection from prior infection. In the U.S., there are more than 19 million children under the age 5 for whom there is no vaccine approved, and tens of millions of people have not been vaccinated. We currently rank 67th in the world for being fully vaccinated and 54th for having its population get an all-important booster shot that preserves a high level of protection against hospitalizations and deaths. When the virus is not contained, as is the case in the world now, its spread creates the potential for new variants.

In these new hosts, the virus could possibly evolve to a new, more deleterious version that attaches better and infects other organs, like the heart or gastrointestinal tract, instead of the lungs. We have already seen people with simultaneous co-infections of two different variants, which enables the swapping of RNA between them and generating a hybrid, potentially worse version of the virus. That swap could also be between an animal and human source, akin to human and bird flu recombination.

The result would be much more difficult for humans to recognize, overriding protection from our spike-protein vaccines or infection-induced immunity. While unlikely, full immune escape by a new variant would put us back to square one of the pandemic.

Even if these scenarios dont materialize, lets remember that Omicron, despite being characterized as a milder form of the virus, can still be deadly for people without immunity. The original Omicron known as BA.1 has sister variants, including BA.2 and BA.3, each with many new and different mutations. A recent study in a lab using an animal model suggested that BA.2 is more disease-causing and more immune-evasive than BA.1.

BA.2 has spread rapidly in some countries such as Denmark, South Africa, India and Sweden. However, all the data to date for BA.2 in people do not support any sign of worse disease or lack of protection from vaccines. BA.2 is not gaining legs in the U.S., but the explanations for this and for the rapid decline of Omicron in many countries remain elusive. At this moment, it does not look like BA.2 poses a threat as a major new variant, but it would not be surprising if we see another variant in future months that deserves a separate Greek letter designation.

The good news is that were probably moving to a relatively quiescent phase, with low numbers of cases and limited severe disease, representing containment of the virus. That is not the same as the pandemic being over. Unfortunately, when states or countries proclaim that we just need to live with the virus and end all restrictions, many people interpret that message as meaning the pandemic is actually over for good. That would be a fantasy given the myriad opportunities for the virus to haunt us in the months and years ahead.

We have been extraordinarily lucky to date getting such highly effective vaccines into the arms of billions of people in a time frame that would never have been considered possible before. These vaccines, with boosters, have held up solidly, protecting vaccinated people against severe disease even though they are directed toward the original strain of the SARS-CoV-2 virus.

Lets hope our luck does not run out. Getting prepared for worst-case scenarios is our best defense, with better genomic, wastewater and digital tracking of the virus, and bolstering protection with everything from better air filtration to accelerating efforts for a variant-proof, pan-coronavirus vaccine. Better to be smart against this formidable virus than lucky.

Eric J. Topol is a professor of molecular medicine at Scripps Research and author of the newsletter Ground Truths.

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COVID-19: All remaining coronavirus restrictions lifted in England – Sky News

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People in England who test positive for COVID are no longer legally required to self-isolate.

From today, all remaining restrictions have been replaced by the government's "living with COVID plan".

This comes just days after guidance for staff and students in most education and childcare settings to undertake twice weekly asymptomatic testing was scrapped.

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What changes from 24 February?

Read more: What will 'living with COVID' mean now coronavirus restrictions have ended in England?

The prime minister said on lifting the restrictions: "Because of the efforts we have made as a country over the past two years, we can now deal with it in a very different way, moving from government restrictions to personal responsibility, so we protect ourselves without losing our abilities and maintaining our contingent capabilities so we can respond rapidly to any new variant."

On removing self-isolation support payments, Labour leader Sir Keir Starmer said: "These are decisions which will hit the lowest paid and the most insecure workers the hardest."

Meanwhile, Transport for London (TfL) has announced passengers will no longer have to wear face coverings.

The Government scrapped the requirement for people in England to wear face coverings on public transport on 27 January 27 but TfL kept the rule on its services.

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What about the devolved nations?

Scotland's legal COVID-19 restrictions, including the wearing of face coverings, will end on 21 March.

In Wales from 28 February people will no longer need to wear face coverings in all indoor places - including schools.

However, masks will still be required in shops, health and care facilities and public transport. If cases continue to fall, it is hoped all mask rules will be lifted by the end of March.

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Northern Ireland's health minister revoked all remaining restrictions on 15 February.

This means that people will not be punished for not following restrictions, though they are still encouraged to do so.

Individual business can also still ask customers to follow rules.

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Will you need a second booster shoot? – Los Angeles Times

Posted: at 2:35 am

With Omicron fading and pressure growing to ease mask rules and other pandemic restrictions, there is growing debate among health officials and experts about if or when a second booster shot will be part of this path toward recovery.

Vaccines and boosters proved highly effective against serious illness from Omicron. But what is also clear, though, is that the defense afforded by vaccines while still robust tends to wane over time, leaving even some vaccinated and boosted individuals more vulnerable than others.

Data released earlier this month by the U.S. Centers for Disease Control and Prevention examined people who got a booster shot of a Pfizer-BioNTech or Moderna vaccine after completing a two-dose primary vaccination series.

During a time where Omicron was the dominant coronavirus variant, vaccine effectiveness against COVID-related emergency department or urgent care visits for people was 87% during the two months after the booster shot, but that fell to 81% during the third month and dropped to 66% for the fourth month after the booster.

I think thats kind of a word of caution, said Dr. George Rutherford, a epidemiologist and infectious diseases expert at UC San Francisco.

A subsequent booster would seemingly help address the issue of waning immunity. But not everyone is convinced a second booster will be needed anytime soon.

Dr. Anthony Fauci, President Bidens chief medical advisor, noted last week that a single booster shot still provides high levels of protection against severe disease. During the Omicron surge, vaccine effectiveness against COVID-19-related hospitalization was 91% during the two months after the booster, fell to 88% during the third month and dropped to 78% for the fourth month, according to data published by the CDC.

Nonetheless, the level of 78 is still a good protective area, Fauci said, adding that he and other officials will continue studying the need for a second booster shot. Recommendations, if needed, will be updated according to the data as it evolves.

The CDC has already recommended that those age 12 and older with moderate or severely compromised immune systems who have already received three doses of vaccinations of the Pfizer or Moderna shots get a fourth dose.

For immune compromised people who got the Johnson and Johnson vaccination as their primary inoculation and have already received a second dose of vaccine, officials now recommend an additional shot, for a total of three doses.

But, in terms of universal boosting, I dont think thats where were going to go anytime soon, Rutherford said, although its possible we may eventually get around to it.

Its not just U.S. officials that are weighing the issue. Some other countries, such as Sweden, the United Kingdom and Israel, are making second booster doses available to certain populations such as residents who are older or at higher risk of severe health impacts from COVID-19.

Dr. Robert Wachter, chair of UC San Franciscos Department of Medicine, tweeted Saturday that evidence of efficacy of second booster from Israel is mixed, however, so I doubt well have one soon in U.S.; maybe by the fall, as a prelude to an annual COVID shot.

Personally, second boost would make me more comfy going maskless, but Im OK waiting for additional data, Wachter added.

For most of those living in the U.S., an additional booster dose would mean four shots total an initial two-dose series of either the Pfizer-BioNTech or Moderna vaccines, plus two subsequent boosters. The shots manufactured by Pfizer and Moderna are collectively known as mRNA vaccines.

For those who initially got the single-dose Johnson & Johnson vaccine, a second booster would mean a third overall shot.

The potential future [recommendation] for an additional boost or a fourth shot for mRNA or a third shot for J&J is being very carefully monitored in real time. And recommendations, if needed, will be updated according to the data as it evolves, Fauci said last week.

In San Francisco, health officials have moved ahead of federal guidance and are already allowing Johnson & Johnson recipients to get a second booster shot.

Despite ongoing discussions around the wisdom of even further boosting, many officials say their top priority at the moment is getting more residents to avail themselves of the additional shot for which theyre already eligible.

Recipients of either the Pfizer-BioNTech or Moderna vaccines should get boosted at least five months after completing their initial two-dose series, according to the CDC. The recommended waiting period is two months for those who received the single-shot Johnson & Johnson vaccine.

Statewide, almost 28 million Californians are already fully vaccinated, according to data from the California Department of Public Health. But only about 13.8 million of them have so far gotten a booster.

Significant gaps also persist across age groups. Among Californians who are at least 65 years old, 72.3% of eligible people have already been boosted. The share is lower, 62.1%, for those between the ages of 50 and 64.

However, fewer than half of eligible adults ages 18 to 49 have been boosted so far. And the same is true for only abut 30% of those between the ages of 12 and 17, state data show.

Health officials say dramatically increasing booster coverage as well as getting more people to roll up their sleeves for the first or second time is key to reducing not just an individuals risk of becoming seriously ill with COVID-19, but the dangers posed by potential new surges.

The work that lies ahead will be focused on the kids who have only recently become eligible, or who remain ineligible for vaccines, to get them fully vaccinated, up-to-date on their immunity also on boosters, with a particular focus on our older, disabled, immunocompromised citizens, with a focus on closing yet another emerging equity gap in the current administration of boosters, Dr. Mark Ghaly, Californias health and human services secretary, said during a recent briefing.

According to the latest available state data, unvaccinated Californians remain almost six times more likely to be infected by the coronavirus than those who have been fully vaccinated and boosted. Theyre also nearly 12 times more likely to be hospitalized with COVID-19 and 17 times more likely to die from the disease than their fully vaccinated and boosted counterparts.

Being fully vaccinated provides really excellent protection against COVID-19. But because the vaccines protection fades over time, people do need that booster dose to be optimally protected, said Los Angeles County Public Health Director Barbara Ferrer.

Ongoing concerns about the potential for future surges is one reason why some California elected officials have voiced support for COVID-19 vaccination requirements.

A group of Democratic lawmakers is pushing a bill that would require employees and independent contractors to be vaccinated as a condition of employment unless they have an exemption based on a medical condition, disability or religious beliefs.

And last October, Gov. Gavin Newsom announced a plan to require COVID-19 vaccinations for all public and private schoolchildren. That would initially take effect for grades 7 through 12 for the school term following the U.S. Food and Drug Administrations full approval of the vaccine for children ages 12 to 15.

Children of that age can currently receive the Pfizer-BioNTech vaccine under emergency authorization, but it isnt clear when the FDA might give its full approval. The vaccine has been fully approved by the FDA for those 16 and older.

Unlike with other vaccines required for schoolchildren, Newsoms plan because it was not enacted through the Legislature would allow parents to cite personal beliefs in refusing to inoculate their children against COVID-19.

There are efforts underway to strengthen that pending requirement. One legislator, state Sen. Richard Pan (D-Sacramento), has proposed a bill that would add COVID-19 vaccines to Californias list of required inoculations for attending K-12 schools, which can be skipped only if a student receives a rare medical exemption.

If passed by the Legislature and signed by the governor, the measure would supplant Newsoms plan.

In an interview broadcast on MSNBCs The Sunday Show with Jonathan Capehart, Newsom touted the states handling of the pandemic as one that has saved lives.

State health officials have published data showing how Californias cumulative per capita COVID-19 death rate is lower than the nations five other most populous states: Texas, Florida, New York, Pennsylvania and Illinois.

Newsom said now is the time to prepare for new surges should they come, such as making sure the state is not caught unprepared yet again with shortages of medical equipment like gowns and N95 masks.

Were realizing that were going to have to live with different variants of this disease for many, many years, Newsom said on the program.

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Will you need a second booster shoot? - Los Angeles Times

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What you need to know about Utah’s new ‘Steady State’ COVID-19 response – Utah Governor

Posted: at 2:35 am

Tags: COVID-19

This past week, we announced that its time for Utahs response to the coronavirus pandemic to shift to better match where we are.

By March 31, our response will transition to what we are calling a Steady State. Some elements of the response will transition to being the responsibility of our highly capable health care systems. This will allow our public health system to refocus on things a public health system would normally look after, like disease surveillance, data collection and reporting, vaccinations, and public awareness. If we see another surge, we will maintain teams and contracts that allow for ramping back up quickly if necessary.

Heres what this means for you.

Testing sites across the state will close as we transition away from community sites to health care settings, private providers for events and travel and at-home testing.

We still recommend certain people seek testing, including older people with high-risk conditions, vulnerable populations and those who work with them and those who often visit vulnerable people. These Utahns should seek testing through their health care provider.

Similar to testing, health care and treatments will become more fully based in the health care system. Monoclonal antibody treatments are available in hospitals and urgent cares statewide. Health care providers across the state are now able to prescribe oral antivirals.

State contracts for COVID positive long-term care facilities are drawing to a close and we are demobilizing UDOH treatment sites. Public health will, however, continue to support navigating vulnerable populations to care.

Utah will continue to provide public information, but less often. We will be decreasing dashboard update frequency from daily to weekly.

We know this isnt over and will continue watching the data closely, tracking wastewater, clinic and ER visits, hospitalizations, and deaths. Were also keeping an eye on new variants or any increase in cases and will ramp back up if needed.

Vaccines have been and will be the surest way out of the pandemic. This administration is dedicated to getting vaccines to as many people as possible.

That includes vaccinations for children younger than five as soon as they are authorized. Weve made great strides in preparing for this: At least 79% of the states health care providers who participate in the Vaccines for Children program are also now enrolled to administer COVID vaccines. We will continue to work with the remaining 21% of providers to convince them to offer COVID vaccines to their patients as well.

We know that vaccination remains the best way to protect yourself from the coronavirus. Please help out our community by getting vaccinated today!

This is not the end of the pandemic. Were still keeping an eye on the future and are ready to ramp back up if necessary. But weve made great strides in fighting the pandemic:

In the past two years, weve

All of the key metrics are moving in the right direction. Vaccines are widely available and hopefully soon everyone older than six months will be eligible to receive the vaccine. Treatments are more widely available, and supplies are improving every week. Testing is available in the comfort of your own home! Hospitals and ICUs and the health care workers who staff them are still at high levels, as they trail behind other indicators, but they too are finally starting to see some relief.

As always, you can find coronavirus information at coronavirus.utah.gov and health.utah.gov.

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What you need to know about Utah's new 'Steady State' COVID-19 response - Utah Governor

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As omicron wave fades, is the U.S. heading toward herd immunity? – PBS NewsHour

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Is omicron leading us closer to herd immunity against COVID-19?

Experts say its not likely that the highly transmissible variant or any other variant will lead to herd immunity.

WATCH: COVID-19 latest: Omicron variant, herd immunity, worldwide vaccine access

Herd immunity is an elusive concept and doesnt apply to coronavirus, says Dr. Don Milton at the University of Maryland School of Public Health.

Herd immunity is when enough of a population is immune to a virus that its hard for the germ to spread to those who arent protected by vaccination or a prior infection.

For example, herd immunity against measles requires about 95% of a community to be immune. Early hopes of herd immunity against the coronavirus faded for several reasons.

One is that antibodies developed from available vaccines or previous infection dwindle with time. While vaccines offer strong protection against severe illness, waning antibodies mean its still possible to get infected even for those who are boosted.

Then theres the huge variation in vaccinations. In some low-income countries, less than 5% of the population is vaccinated. Rich countries are struggling with vaccine hesitancy. And young children still arent eligible in many places.

As long as the virus spreads, it mutates helping the virus survive and giving rise to new variants. Those mutants such as omicron can become better at evading the protection people have from vaccines or an earlier infection.

Populations are moving toward herd resistance, where infections will continue, but people have enough protection that future spikes wont be as disruptive to society, Milton says.

Many scientists believe COVID-19 will eventually become like the flu and cause seasonal outbreaks but not huge surges.

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As omicron wave fades, is the U.S. heading toward herd immunity? - PBS NewsHour

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International Space Station largely isolated from tensions over Ukraine – PBS NewsHour

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ATLANTA (AP) Tensions in eastern Ukraine and heightened Western fears of a Russian invasion should not have a significant impact on the International Space Station or U.S.-Russia cooperation in space, the former head of the National Space Council told The Associated Press.

Scott Pace, who served as executive secretary of the space council under President Donald Trump and is now the director of the Space Policy Institute at George Washington University, said the space station has been largely isolated from political events.

Its possible to imagine a break with Russia that would endanger the space station, but that would be at the level of a dropping diplomatic relations, said Pace. That would be something that would be an utterly last resort so I dont really see that happening unless there is a wider military confrontation.

WATCH: Can asteroids be veered away from Earth? New NASA spacecraft aims to find out

The space station, an international partnership of five space agencies from 15 countries, including Canada, several countries in Europe, Japan, Russia and the United States, launched in 1998 and morphed into a complex thats almost as long as a football field, with eight miles of electrical wiring, an acre of solar panels and three high-tech labs.

It marked two decades of people continuously living and working in orbit in 2020.

The first crew American Bill Shepherd and Russians Sergei Krikalev and Yuri Gidzenko blasted off from Kazakhstan on Oct. 31, 2000. Two days later, they swung open the space station doors, and clasped their hands in unity.

The three astronauts got along fine but tension sometimes bubbled up with the two Mission Controls, in Houston and outside Moscow.

Shepherd, during a NASA panel discussion with his crewmates, said he got so frustrated with the conflicting marching orders that he insisted they come up with a single plan.

Russia kept station crews coming and going after NASAs Columbia disaster in 2003 and after the space shuttles retired in 2011.

It is a way of undertaking common endeavors but that power is not infinite and terrestrial conflicts on Earth can still get in the way, said Pace. Space is ever more critical to our daily life and its something everybody should be aware of.

Earlier this year, NATO Secretary-General Jens Stoltenberg, who chaired a meeting of the NATO-Russia Council in Brussels, said he was keen to discuss ways to prevent dangerous military incidents or accidents involving Russia and the Western allies, reducing space and cyber threats, as well as setting limits on missile deployments and other arms control initiatives.

There have been concerns raised in Congress about the impact that conflict over Ukraine could have on the International Space Station.

Lawmakers have specifically exempted space cooperation from previous sanctions and can be expected to make similar arguments against targeting it as the administration considers its next steps over Ukraine.

On Wednesday, Russia began evacuating its embassy in Kyiv, and Ukraine urged its citizens to leave Russia.

Russian lawmakers authorized President Vladimir Putin to use military force outside his country and President Joe Biden and European leaders responded by slapping sanctions on Russian oligarchs and banks.

Both leaders signaled that an even bigger confrontation could lie ahead.

Putin has yet to unleash the force of the 150,000 troops massed on three sides of Ukraine, while Biden held back on the toughest sanctions that could cause economic turmoil for Russia but said they would go ahead if there is further aggression.

The sanctions underscored the urgency felt by Western nations to blunt the conflict.

Four NASA astronauts, two Russian cosmonauts and one European astronaut are currently on the space station.

AP Diplomatic Writer Matthew Lee in Washington contributed to this report.

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International Space Station largely isolated from tensions over Ukraine - PBS NewsHour

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How to incinerate the International Space Station – Engadget

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It took NASA and its partners nearly four dozen trips between 1998 and 2010 to haul the roughly 900,000 pounds worth of various modules into orbit that make up the $100 billion International Space Station. But come the end of this decade, more than 30 years after the first ISS component broke atmosphere, the ISS will reach the end of its venerable service life and be decommissioned in favor of a new, privately-operated cadre of orbital research stations.

NASA

The problem NASA faces is what to do with the ISS once its been officially shuttered, because its not like we can just leave it where it is. Without regular shipments of propellant reactant to keep the station on course, the ISS orbit would eventually degrade to the point where its forward momentum would be insufficient to overcome the effects of atmospheric drag, subsequently plummeting back to Earth. So, rather than wait for the ISS to de-orbit on its own, or leave it in place for the Russians to use as target practice, NASA will instead cast down the station from upon high like Vader did Palpatine.

NASA is no stranger to getting rid of refuse via atmospheric incineration. The space agency has long relied on it in order to dispose of trash, expended launch vehicles, and derelict satellites. Both Americas Skylab and Russias Mir space stations were decommissioned in this manner.

Skylab was Americas first space station, for the whole 24 weeks it was in use. When the final 3-astronaut crew departed in early 1974, the station was boosted one last time to 6.8 miles further out in a 289-mile graveyard orbit. It was expected to remain there until the 1980s when increased solar activity from the waxing 11-year solar cycle would eventually drag it down into a fiery reentry. However, astronomers miscalculated the relative strength of that solar event, which pushed up Skylabs demise to 1979.

In 1978, NASA toyed with the idea of using its soon-to-be-completed Space Shuttle to help boost Skylab into a higher orbit but abandoned the plan when it became clear that the Shuttle wouldnt be finished in time, given the accelerated reentry timetable. The agency also rejected a proposal to blow the station up with missiles while still in orbit. The station eventually came down on July 11th, 1979, though it didnt burn up in the atmosphere as quickly as NASA had predicted. This caused some rather large pieces of debris to overshoot the intended Indian Ocean target South-Southeast of South Africa and instead land in Perth, Australia. Despite NASAs calculations of a 1 in 152 chance that a piece of the lab could hit someone during its de-orbit, no injuries were reported.

Mir's deorbit went much more smoothly. After 15 years of service it was brought down on March 23rd, 2001, in three stages. First, its orbit was allowed to degrade to an altitude of 140 miles. Then, the Progress M1-5 spacecraft basically an attachable rocket designed specifically to help deorbit the station docked with the Mir. It subsequently lit its engine for a little over 22 minutes to precisely put the Mir down over a distant expanse of the Pacific Ocean, east of Fiji.

As for the ISS oncoming demise, NASA has a plan or at least a pretty good idea for whats going to happen. "We've done a lot of studies," Kirk Shireman, deputy manager of NASA's space station program, told Space.com in 2011. "We have found an orbit and a change in velocity that we believe is achievable, and it creates a debris footprint thats all in water in an unpopulated area."

According to NASA standards specifically NASA-STD-8719.14A, Process for Limiting Orbital Debris the risk of human casualty on the ground is limited to less than 1 in 10,000 (< 0.0001). However, a 1998 study conducted by the ISS Mission Integration Office discovered that an uncontrolled reentry would carry an unacceptable casualty probability of between .024 to .077 (2 in 100 to 8 in 100). A number of controllable decommissioning alternatives have been discussed over the decades, including boosting the ISS farther into orbit in the event of an unexpected evacuation of the stations crew.

"We've been working on plans and update the plans periodically," Shireman continued. "We dont want to ever be in a position where we couldnt safely deorbit the station. It's been a part of the program from the very beginning."

Beginning about a year before the planned decommissioning date, NASA will allow the ISS to begin degrading from its normal 240-mile high orbit and send up an uncrewed space vehicle (USV) to dock with the station and help propel it back Earthward. The ultimate crew from the ISS will evacuate just before the station hits an altitude of 115 miles, at which point the attached USV will fire its rockets in a series of deorbital burns to set the station into a capture trajectory over the Pacific Ocean.

NASA has not yet settled on which USV will be employed. A 2019 plan approved by NASAs safety council, ASAP, relied on Roscosmos to outfit and send up another Progress spacecraft to do what it did for the Mir. However, that vehicle might not actually be available when the ISS is set to come down because Russias commitment to the ISS program terminates in 2024. In April of last year, Russian state media began making noise that the country would abandon the station entirely by 2025, potentially stripping parts from this station to reuse in its upcoming national station and leaving the ISS without a reliable way to break orbit. The ESAs Automated Transfer Vehicle or NASA's Orion Multi-Purpose Crew Vehicle, though still in development, are both potential alternatives to the Progress.

NASA is continuing to work with its international partners to ensure a safe deorbit plan of the station and is considering a number of options," spokeswoman Leah Cheshier told UPI via email in 2021, declining to elaborate on what those options might entail but adding that any deorbiting mission would be "shared by the ISS partnership and is negotiation-sensitive at this time."

The fall of the ISS is sure to be a spectacle on par with the international hubbub surrounding Skylabs demise, but is still nearly a decade away and there is plenty of science still left to do. According to the January 2022 International Space Station Transition report:

The ISS is now entering its third and most productive decade of utilization, including research advancement, commercial value, and global partnership. The first decade of ISS was dedicated to assembly, and the second was devoted to research and technology development and learning how to conduct these activities most effectively in space. The third decade is one in which NASA aims to verify exploration and human research technologies to support deep space exploration, continue to return medical and environmental benefits to humanity, continue to demonstrate U.S. leadership in LEO through international partnerships, and lay the groundwork for a commercial future in LEO.

More than half of the experiments performed aboard the ISS nowadays are for non-NASA users, according to the report including nearly two dozen commercial facilities hundreds of experiments from other government agencies, academia, and commercial users to return benefits to people and industry on the ground. This influx of orbital commercial activity is expected and being actively encouraged to further increase over the next few years until humanity can collectively realize Jeff Bezos dream of building a low Earth orbit mixed-use business park.

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How to incinerate the International Space Station - Engadget

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