Daily Archives: November 17, 2021

Eloxx Pharmaceuticals Reports Positive Topline Results from Monotherapy Arms of Phase 2 Clinical Trial of ELX-02 in Class 1 Cystic Fibrosis Patients -…

Posted: November 17, 2021 at 1:33 pm

ELX-02 monotherapy dosed at 1.5mg/kg/day demonstrated a statistically significant 5.4mmol/L mean sweat chloride reduction, an established surrogate for restoration of CFTR biological activity

ELX-02 monotherapy results support advancement of ELX-02 into Phase 3 clinical development

First patient dosed in Phase 2 ELX-02 expansion treatment arms evaluating combination with ivacaftor; topline data expected by the end of the first half of 2022

Company to host conference call and webcast Wednesday, November 17, 2021 at 8:30 am ET

WATERTOWN, Mass., Nov. 17, 2021 (GLOBE NEWSWIRE) -- Eloxx Pharmaceuticals, Inc. (NASDAQ: ELOX), a leader in ribosomal RNA-targeted genetic therapies for rare diseases, today announced positive topline results from the monotherapy arms of its Phase 2 clinical trial of ELX-02 in Class 1 cystic fibrosis (CF) patients with at least one G542X nonsense allele mutation. ELX-02 was well tolerated and achieved a statistically significant 5.4mmol/L reduction in sweat chloride in patients at the1.5mg/kg/day dose.

The intra-patient dose escalation stage of the trial has successfully identified 1.5 mg/kg/day as the dose for further development. Based on the statistically significant monotherapy results observed at the 1.5mg/kg/day dose, planning for the advancement of ELX-02 into Phase 3 clinical development has started. The U.S. Food and Drug Administration (FDA) has granted Fast Track designation for ELX-02. In addition, ELX-02 has also been granted Orphan Drug Designation for the treatment of CF patients with nonsense mutations by the FDA and orphan medicinal product designation by the European Medicines Agency.

We are highly encouraged with the topline results from the monotherapy arms of our Phase 2 trial, and believe that ELX-02, if approved, has potential to transform the lives of Class 1 CF patients with nonsense mutations, who do not have any available therapies, said Sumit Aggarwal, President and Chief Executive Officer of Eloxx.

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Topline Results of ELX-02 Phase 2 Monotherapy Trial in Class 1 Nonsense CF Patients

The Phase 2 clinical trial of ELX-02 was designed to evaluate safety and assess biological activity in G542X nonsense mutation Class 1 CF patients as monotherapy and in combination with ivacaftor. Topline results for the intra-patient dose escalation monotherapy arms are summarized below:

ELX-02 was generally well tolerated in the trial, with no treatment-related serious adverse events noted.

The study met a key secondary endpoint by showing a statistically significant reduction in mean sweat chloride of 5.4 mmol/L (p value=0.0218, n=12 patients) after one week of therapy for ELX-02 dosed at 1.5mg/kg/day.

Short term reductions in sweat chloride have been shown to correlate with biologic activity of the CFTR protein and translate to lung function improvement over the long term.

A potential dose response trend was also seen in mean sweat chloride reduction, with a stronger dose response trend in the subset of patients (post-hoc) that completed the 1.5mg/kg/day dosing.

The reduction in mean sweat chloride in Class 1 CF patients with nonsense mutations who received 1.5mg/kg/day in the trial is similar to the activity in Class 1 CF patient organoids treated with ELX-02 in preclinical experiments.

As expected, no change was observed in forced expiratory volume (FEV1) due to short treatment duration.

While the trial was not designed as a longer-term efficacy study and did not compare ELX-02 to any other agent, results from prior Phase 2 trials with FDA-approved agents for CF can serve as a contextual reference for the level of sweat chloride reduction observed and its potential clinical relevance.

Results of a Phase 2 study with lumacaftor and lumacaftor/ivacaftor combination (Orkambi), an FDA-approved combination CF agent, demonstrated 4.1mmol/L to 5.1 mmol/L reductions in sweat chloride over two- and three-week study durations in Class 2 CF patients with HomF50del mutations.

Results of a phase 2 study with tezacoftor/ivacaftor combination (Symdeko), an FDA-approved combination CF agent, demonstrated a 1.8mmol/L to 5.2 mmol/L reduction in sweat chloride over 28 days in Class 2 CF patients with HomF50del mutations.

Treatment with both these agents resulted in improved lung function as measured by forced expiratory volume FEV1 with longer treatment duration in subsequent Phase 3 trials with Orkambi and Symdeko.

These significant results for sweat chloride, a surrogate for CFTR protein function in patients, are very exciting. I look forward to working with Eloxx on future development of ELX-02, said Prof. Eitan Kerem, Head of The Division of Pediatrics Hadassah Medical Center.

Planned Next Steps for ELX-02 CF Program

ELX-02 in combination with other CF therapies.

First patient dosing has occurred in the expansion arm of the Phase 2 trial, which includes a combination of ELX-02 and Kalydeco (ivacaftor), a CFTR protein potentiator. In preclinical studies, Class 1 CF patient organoids had a 2- to 3-fold higher swelling response with a combination of ELX-02 and Kalydeco than with ELX-02 as a monotherapy. Topline results are expected by the end of the first half of 2022.

With dosing of the first patient, we have now advanced ELX-02 into the Phase 2 combination study and have begun preparations for Phase 3 clinical development, said Vijay Modur MD, PhD, Head of Research & Development of Eloxx.

Inhaled delivery of ELX-02

Eloxx has also begun evaluation of inhaled (nebulizer-based) delivery of the current subcutaneous formulation of ELX-02. Eloxx believes that inhaled delivery has the potential to further improve the activity of ELX-02 as a single agent and in combination with other drugs given potential for increased drug exposure in the lung versus plasma. Prior animal studies have shown a 19-fold increase in ELX-02 exposure at a similar dose when administered as an inhalation agent versus subcutaneously. We expect to submit an Investigational New Drug application the second half of 2022.

About Class 1 CF

CF patients with a Class 1 nonsense mutation remain highly underserved with no approved disease modifying therapies. An estimated 10-12% of CF patients are Class 1 patients with one or both alleles harboring nonsense mutations, leading to less than full length CFTR proteins on the cell membrane in these patients.

Conference Call and Webcast

Eloxxs management will host a conference call and webcast today at 8:30 a.m. ET. A live webcast of the conference call can be accessed through the Investors tab on the Eloxx website, and a replay will be available online after the call. For those planning to ask a question, the dial-in number for the conference call is (866) 913-8546 for domestic participants and (210) 874-7715 for international participants, with Conference ID # 2393967. Please dial in at least 15 minutes in advance to ensure a timely connection to the call.

About Eloxx Pharmaceuticals

Eloxx Pharmaceuticals, Inc. is engaged in the science of ribosome modulation, leveraging its innovative TURBO-ZM chemistry technology platform in an effort to develop novel Ribosome Modulating Agents (RMAs) and its library of Eukaryotic Ribosome Selective Glycosides (ERSGs). Eloxxs lead investigational product candidate, ELX-02, is a small molecule drug candidate designed to restore production of full-length functional proteins. ELX-02 is in clinical development, focusing on cystic fibrosis (US Trial NCT04135495, EU/IL Trial NCT04126473). Eloxx also has preclinical programs focused on select rare diseases, including inherited diseases, cancer caused by nonsense mutations, kidney diseases, including autosomal dominant polycystic kidney disease, as well as rare ocular genetic disorders.

For more information, please visit http://www.eloxxpharma.com.

Forward-looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements other than statements of present and historical facts contained in this press release, including without limitation, statements regarding our expected cash burn and future financial results, the expected timing of trials and results from clinical studies of our product candidates and the potential of our product candidate to treat nonsense mutations are forward-looking statements. Forward-looking statements can be identified by the words aim, may, will, would, should, expect, explore, plan, anticipate, could, intend, target, project, contemplate, believe, estimate, predict, potential, seeks, or continue or the negative of these terms similar expressions, although not all forward-looking statements contain these words.

Forward-looking statements are based on management's current plans, estimates, assumptions and projections based on information currently available to us. Forward-looking statements are subject to known and unknown risks, uncertainties and assumptions, and actual results or outcomes may differ materially from those expressed or implied in the forward-looking statements due to various important factors, including, but not limited to: our ability to progress any product candidates in preclinical or clinical trials; the uncertainty of clinical trial results and the fact that positive results from preclinical studies are not always indicative of positive clinical results; the scope, rate and progress of our preclinical studies and clinical trials and other research and development activities; the competition for patient enrollment from drug candidates in development; the impact of the global COVID-19 pandemic on our clinical trials, operations, vendors, suppliers, and employees; our ability to obtain the capital necessary to fund our operations; the cost of filing, prosecuting, defending and enforcing any patent claims and other intellectual property rights; our ability to obtain financial in the future through product licensing, public or private equity or debt financing or otherwise; general business conditions, regulatory environment, competition and market for our products; and business ability and judgment of personnel, and the availability of qualified personnel and other important factors discussed under the caption Risk Factors in our Quarterly Report on Form 10-Q for the quarter ended September 30, 2021, as any such factors may be updated from time to time in our other filings with the SEC, accessible on the SECs website at http://www.sec.gov and the Financials & Filings page of our website at https://investors.eloxxpharma.com/financial-information/sec-filings.

All forward-looking statements speak only as of the date of this press release and, except as required by applicable law, we have no obligation to update or revise any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances or otherwise.

Contact

InvestorsJohn Woolfordjohn.woolford@westwicke.com443.213.0506

MediaLaureen Cassidylaureen@outcomescg.com

SOURCE: Eloxx Pharmaceuticals, Inc.

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‘This is my last option:’ Ottawa woman with cystic fibrosis says insurance won’t cover life-saving medication – CTV Edmonton

Posted: at 1:33 pm

OTTAWA -- An Ottawa 23-year old with cystic fibrosis says shes in need of a life-saving medication which costs $300,000 dollars a year, but says her private insurance wont pay for it.

I have been basically told that this is my last option, Sara Aldrich says.

Aldrich was diagnosed with cystic fibrosis at an early age, and has lived a mostly active life.

Both my brother and I played competitive soccer, I played for eleven years, she says, we were always out and doing something - some kind of sport.

But she says over the past three years, that changed. Her condition, which affects the lungs, got worse - making everyday tasks difficult.

When I was healthy, I never even thought about how easy it was to do, but now , walking up the stairs I usually cough, I usually end up throwing up. So my life has kind of completely altered since my lung function has gone down.

Aldrich says a new treatment, called Trifakta would change her life.

My lung function is the lowest its ever been, and I cant see it ever going back up unless I get Trikafta.

The drug is approved for use in Canada, but not covered by her private insurance.

The price would need to be reduced by at least 80 to 90 percent for them to be able to pay for it; and, they said that the price of the drug is currently outweighing the benefits of it.

Kim Steele, director of government and community relations with Cystic Fibrosis Canada, says Aldrich is not the only one to be denied,

Were in this weirdly unique situation, in which Canadas public-payers, so our governments, have moved to cover this drug more quickly, than most private insurers, and that just doesnt happen in Canada, she says.

Not everybody can get public insurance; if you have private insurance, depending on where you live in Canada, your government wants to bill them first; and, if your private insurer is not covering it, its a whole bunch of work to try and get it through the public system.

Steele adds that Trikafta treats 98 per cent of the cystic fibrosis community,

Its the single biggest transformation in the history of cystic fibrosis. Its a therapy that is not only slowing the progression of the disease in people, but it is helping people get off the lung transplant list and get on with life.

Aldrich is applying for an OHIP program aimed at young people to hopefully pay for the drug. But her goal is to raise awareness about her situation and help others.

Continuing to fight for everyone else that has CF, and needs this drug - I dont want to stop here.

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Iowa grandmother starts charity devoted to curing cystic fibrosis, gets attention of Iowa State’s Matt Campbell – Ames Tribune

Posted: at 1:33 pm

Lynn Marr-Moore of Kelly broke down in tears eight years ago when she found out her granddaughter Charlotte Charlie Hugunin would be born with cystic fibrosis.

The tears gave way to a determination to find a cure for the life-threatening illness that affects the respiratory and digestive systems.

I cried for two weeks because we knew Charlie was going to be born with CF, but its remarkable now how much more hope we have than we did eight years ago, Marr-Moore said. We went from feeling so hopeless to feeling so hopeful.

Eight years ago, Marr-Moore formed a nonprofit called Charlies Angels. It startedwith a fundraising bicycle ride, a suggestion of Charlies father Tim, a Nevada High School graduate. The family, including mother Jenny and older sister Alex, lives in Norwalk.

The nonprofit hasgrown to include about a half-dozen events a year, including the Breathing Life Into the Future gala, which will be held Saturday, Nov. 20, at the Hotel Pattee in Perry.

As long as we are going to raise money for research, we are going to have a good time doing it, Marr-Moore said. Charlie is my everyday loving reminder of what I am supposed to be doing with my life.

More Ames news: $200,000 in Arts Capital Grants available, applications due Dec. 3

To date, Charlies Angels has raised about $165,000 and has been recognized by the Cystic Fibrosis Foundation.

For a group our size, we raised the most money of all the groups in the United States, Marr-Moore said. We were honored, but were really just here to get this child well, along with the other children with CF.

Cystic fibrosis is considered an orphan disease. Worldwide, there are only about 300,000 patients. Children had a life expectancy of just 3 or 4 years in the beginning. Now we actually have patients who are 74 because the research has come so far.

All of the money raised by Charlies Angels goes to fund research. It is 100% volunteer work.

When we raise money for cystic fibrosis through Charlies Angels, our money actually stays in the state of Iowa, Marr-Moore said. There are 10 research centers nationwide. Our research center is located at the University of Iowa. Its not part of the university, but they have the lab facilities.

Its the only research center in the United States that's working on the cure. And we have been invited over there several times to meet with the researchers.

The Breathing Life Into the Future gala starts at 5:30 p.m. with check-in and a cash bar. Dinner is at 6 p.m. The evening will includeguest speaker Jim Scholten, a live auction, and a performance by the dueling pianos of Mike and Andy from 8-10 p.m.

More: Whimsical Wine Trailer owner recognized in '40 Women to Watch' list, continues to grow biz

Charlie has won the heart of Iowa State football coach Matt Campbell, Marr-Moore said. She said it began when she was in his office one day hoping to talk to him.

I told him I have a sick granddaughter, and he was so receiving, Marr-Moore said. He said, Tell me about Charlie. So I did, and when I was done he asked how he could help.

Thats how the event Lunch with the Coach started. It is an annual opportunity for Cyclone fans to attend a luncheon and hear from Campbell.

I think Charlie was 3 years old the year coach Campbell invited her to spring practice, Marr-Moore said. She was wearing her Iowa State shirt and a tutu and her cowboy boots. After practice, Matt walked over to us and picked up Charlie.

She told coach Campbell, You know, my dad likes those Hawkeyes. And Matt just smiled and said, Well fix that.

More: Sitting more is linked with worse mental health, Iowa State study says. Light exercise can help

It's Charlie's job tointroduceCampbell at the lunch. The last time, she stood on a chair so she could reach the microphone.

Charlie said, Matt Campbell is my best friend. Hes helping me so Im not sick. And hes really cute, and the place just exploded, Marr-Moore said.

Events to watch for in 2022 include Noodles and Doodles, a pasta dinner by gourmet chef Tim Winter; apainting class with Slater artistShawn Palek; the annual bike ride in the summer; a fashion show starring Charlie; and a continual can drive, where people can donate their empties anytime.

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Matt Gurney: Canada’s aging fighter jets will keep on aging because Trudeau has no incentive to replace them – National Post

Posted: at 1:33 pm

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This may be an impossible problem to solve, but it's an easy one to diagnose

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My colleague David Pugliese reported in the Ottawa Citizen this week that the seemingly never-ending effort to replace our fighter jet fleet has run into yet another delay, marking just the latest low point in our appalling efforts to procure military equipment, of which much is needed. The government was supposed to have selected finalists among the would-be providers of our next generation jet this month, with the selection of a final winner scheduled for early next year. The government no longer says it is committed to that timeline. Its hard to imagine that that means anything else than yet more delays, which is typical of a pattern of deliveries not matching announcements flashy press releases have promised more Rangers with modern weapons, reconnaissance drones, Arctic patrol ships for the Navy, and eventually, new fighter planes to replace the aging CF-18s. Its a long-running problem.

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How long running, you might ask? Well, long running enough that in the paragraph above, everything from flashy to aging CF-18s was plucked verbatim out of a column from 2009, written by yours truly in this very same newspaper.

As is the way of things, those aging jets have kept right on aging. There has been some progress. During these last 12 years, we were able to get new bolt action rifles for the Rangers, and one of the Arctic patrol ships is now in service. That concludes the good news.

The only thing that has really changed during that time is that now we have Liberals in power instead of Conservatives, and our elderly CF-18s are even more elderly. If anything, the geopolitical situation around the world has only gotten worse as our jets have gotten older. Canada now routinely sends jets to Europe to assist eastern European NATO allies patrol their skies. A Canadian warship recently joined other allied vessels in a show of strength near Taiwan, which is in Beijings crosshairs. Our alliance with the United States, long our guarantor of protection from external threat, has been through incredible strains these last few years. We simply cannot take for granted that they would defend us in a way that generations of Canadian policymakers had comfortably, if perhaps wrongly, assumed.

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This may be an impossible problem to solve, but its an easy one to diagnose: both Stephen Harper and Justin Trudeau have publicly recognized the necessity of replacing the CF-18s; both of them have privately clearly paled at the tens of billions of dollars it will cost to do so. This has been an urgent priority for 20 years. There is simply no incentive for someone to step up, take the reins and fix this problem. And theres always something more politically sexy to spend the money on.

So our pilots take off every day in planes that are at risk of honest-to-God metal fatigue failure if they have to fly too fast or turn sharply. Flying fast and turning sharply, as the reader may know, is the sort of thing that fighter jets could conceivably need to do in the middle of, you know, a mission or something.

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Today its the jets, tomorrow it will be something else. Maybe we will try and fail again to replace our 9mm pistols, which were built when Hitlers panzers roamed France. Maybe our plan to replace our navy surface warships will run into some other program-threatening delay or budget overrun. And God help us all, but were gonna need to get going on a submarine replacement sooner rather than later, and if we do an exceptionally good job at it, perhaps my great grandchildren will one day be writing columns in the Planetary Post noting the ongoing delays in delivery.

Conservatives will blame Trudeau for the latest CF-18 delay, and fairly so. He is the guy in the big chair. Hes the boss. Weve had a few elections of late and Trudeaus party keeps winning them. Theres nothing wrong with saying the buck stops with him, because, frankly, it does. Liberals, of course, for their part will note that the Conservatives also dropped the ball on this file and left Trudeau, way back in 2015, not only with a few dozen ancient fighter jets but also a navy that had rusted out. Those Liberals, right as they are, will shift uncomfortably in their seats when its pointed out that theyve been in office for six years since, and as noted above, not much has gotten better.

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And it wont. It just wont. This is not a political problem. Its easy to blame Liberals, or Conservatives, or politicians generally, but at this point that is a cop out. This ones on us. This is a Canadian problem. We are bad at this because we do not value it. If we valued it, the government would at least attempt to meet the demand for better. Canadian government competency is something no one has ever gone bust betting against, but we arent even trying. The man who was until very recently the minister of national defence couldnt even seem to get on top of the militarys HR problems, amid the unfolding backdrop of the sexual misconduct omnishambles at the top of the Forces command structure. But sure, this government will get right on replacing many tens of billions of dollars of equipment.

Anyway, what more can be said? Lets check back in another 12 years. Perhaps by then well be flying new jets. But then again, maybe not.

National Post Twitter.com/MattGurney

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Why Is Freedom of Speech an Important Right? When, if Ever …

Posted: at 1:32 pm

While the text and principle of the First Amendment have stayed the same, the courts interpretation has indeed changed over time. Judges, lawmakers and scholars continue to struggle with balancing strong speech protections with the necessity of maintaining a peaceful society.

What do you think? Why is the freedom of speech an important right? Why might it be important to protect even unpopular or hurtful speech? And yet, when might the government draw reasonable limits on speech, and why?

_________

Before answering this question, read the full text of the amendment. What does it say about speech?

Congress shall make no law respecting an establishment of religion, or prohibiting the free exercise thereof; or abridging the freedom of speech, or of the press; or the right of the people peaceably to assemble, and to petition the Government for a redress of grievances.

Next, read these excerpts from three recent articles about free speech cases that might affect your life:

In a September 2017 article, High Schools Threaten to Punish Students Who Kneel During Anthem, Christine Hauser writes:

The controversy over kneeling in protest of racial injustice moved beyond the world of professional sports this week, when a number of schools told students they were expected to stand during the national anthem.

On Long Island, the Diocese of Rockville Centre, which runs a private Catholic school system, said students at its three high schools could face serious disciplinary action if they knelt during the anthem before sporting events.

In a June 2018 article, Colleges Grapple With Where or Whether to Draw the Line on Free Speech, Alina Tugend writes:

It has happened across the country, at small private colleges and large public universities: an invited guest is heckled or shouted down or disinvited because of opposing political views.

And the incident is followed by a competing chorus of accusations about the rights of free speech versus the need to feel safe and welcome.

Its something those in higher education have grappled with for decades. But after the 2016 presidential election and the increasing polarization of the country, the issue has taken on a new resonance.

In another June 2018 article, Supreme Court Strikes Down Law Barring Political Apparel at Polling Places, Adam Liptak writes:

The Supreme Court on Thursday struck down a Minnesota law that prohibits voters from wearing T-shirts, hats and buttons expressing political views at polling places.

In a cautious 7-to-2 decision, the court acknowledged the value of decorum and solemn deliberation as voters prepare to cast their ballots. But Chief Justice John G. Roberts Jr. wrote that Minnesotas law was not capable of reasoned application.

Students, read at least one of the above articles in its entirety, then tell us:

Why is the freedom of speech an important right? Why do you think its worth protecting?

What is the value in protecting unpopular speech?

The Supreme Court has determined that certain types of speech, such as fighting words, violent threats and misleading advertising, are of only low First Amendment value because they dont contribute to a public discussion of ideas, and are therefore not protected. Even though the text of the First Amendment does not make any distinction between low and high value speech, do you think the court is correct in ruling that some categories of speech are not worth protecting? What types of speech would you consider to be low value? What types of speech are high value, in your opinion?

What do you think about the free speech issues raised in the three articles above? For example:

Should students be allowed to kneel during the national anthem? Why? Should colleges be allowed to forbid controversial or offensive guests from speaking on campus? Why? Should individuals be able to wear overtly political T-shirts or hats to the polling booth? Why?

When might the government draw reasonable limits to the freedom of speech, and why?

We now want to ask you an important constitutional question: When does the First Amendment allow the government to limit speech? We want to hear what you think. But to clarify, were not asking for your opinion about policy. In other words, were not asking whether a certain type of speech, like flag burning or hate speech, should be protected or prohibited. Instead, were asking you to interpret the Constitution: Does the First Amendment protect that speech?

Do your best to base your interpretation on the text of the amendment itself and your knowledge of how it can be understood. You may want to consult this essay in the National Constitution Centers Interactive Constitution to learn more about how scholars and judges have interpreted the First Amendment, but rest assured, you dont have to be a Supreme Court justice to have an opinion on this matter, and even the justices themselves often disagree.

When you interpret the First Amendment, what do you think it has to say about the free speech issues raised in the three articles. For example:

Does the First Amendment protect the right of students at government-run schools (public schools) to protest? What about students who attend private schools? Does the First Amendment allow private colleges to prohibit certain controversial speakers? What about government-run colleges (public colleges)? Finally, does the First Amendment protect voters right to wear whatever they want to the polling booth?

Are any of your answers different from your answers above, when you answered the three should questions?

When scholars, judges and lawmakers try to balance strong speech protections with the goal of maintaining a peaceful society, what ideas or principles do you think are most important for them to keep in mind? Explain.

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Opinion | Democrats Shouldnt Panic. They Should Go Into Shock. – The New York Times

Posted: at 1:32 pm

At the same time, Bruce Cain of Stanford suggested that a Democratic defeat in 2022 could be a potentially favorable development for the partys long term prospects:

It is quite possible that losing in the 2022 midterm is the best path to winning the presidency in 2024. It will put the Republicans in a put up or shut up spot vis--vis problems facing the country, and Biden meanwhile can work the middle without looking over his left shoulder.

Cain took this logic a step further to argue that

In retrospect the worst thing that happened to Biden was the Democrats winning the two seats in Georgia. It raised expectations among some in his party that they could go left legislatively while the political sun was shining when in reality the political math was not there for that kind of policy ambition.

Cain added:

The best hope for the Democrats is that Trump will undermine some Republicans during his vengeance tour and that the weakness of the people who want to run under his banner will create some unexpected wins for the Democrats.

Howard Rosenthal, a political scientist at N.Y.U., added this observation:

Pundits, who have to earn a living, always want to impute causality to election losses. However, the midterm cycle is just normal. Voters tend to balance the president. Over time, they also create divided government at the state level.

A surprising number of those I contacted made the case that the chaotic withdrawal from Afghanistan did more lasting damage to Biden than might have been expected.

The extended wall-to-wall media coverage of the hurried exit from Afghanistan probably served as a catalyst for some folks to update their views on Bidens performance and take into consideration both the foreign and domestic concerns, Ted Brader, a political scientist at the University of Michigan, wrote in an email:

Im skeptical that those events themselves drove the lower assessments; Americans weigh domestic events much heavier than foreign affairs. But the heightened attention and criticism can serve as an attention-getting call to re-evaluate the president: Wait, how well is he doing his job? As political science research has convincingly demonstrated, bipartisan criticism, as we saw with the Afghan withdrawal, in particular, opens the door to weaker support among independents and members of the presidents own party.

Gary Jacobson, a political scientist at the University of California, San Diego, wrote me that things touching on competence (Afghanistan, border, congressional inaction) are probably the most important in driving down Bidens ratings, but for the future, it is inflation and the general economy that will matter most, I think.

Herbert Kitschelt, a political scientist at Duke, contended in an email that the problems facing Biden and his Democratic colleagues run deeper than any single issue:

Biden was elected as a moderate to put back some sanity into government through a steady hand and incremental reforms. Instead, a wing of the Democratic Party took the 2020 election in which the Democratic Party lost a surprising number of House seats as a voter mandate to implement a pretty fundamental program of social reform and sociocultural change. While I personally might like a lot of these policy initiatives myself, I also realize that this programmatic ambition is consistent with the wishes of only a minority of core Democratic voters, and certainly not that of the centrist voters who prevented Trump from being re-elected.

The history of midterm elections suggests that substantial House losses for the party of the incumbent president are inevitable, barring such unusual circumstances as public hostility to the Republican-led impeachment of Bill Clinton in 1998 and the Sept. 11 terrorist attacks raising Republican support in 2002 the only two times since that the incumbent party gained seats since World War II.

In 2010, Joseph Bafumi, Robert Erikson and Christopher Wlezien, political scientists at Dartmouth, Columbia and the University of Texas at Austin, published Balancing, Generic Polls and Midterm Congressional Elections, in which they argued that between February and Election Day, the presidential partys vote strength almost always declines. But, they continued,

the degree of decline is unrelated to the publics evaluation of the president. Clearly, during the midterm election year, the electorate shifts away from the presidential party in its vote choice for reasons that have nothing to do with the electorates attitudes toward the president. By default, this is balancing: The electorate votes against the presidential party to give more power to the other party.

In a 1988 paper, The Puzzle of Midterm Loss, Erikson examined every midterm contest since 1902 and explicitly rejected the theory that such contests are a negative referendum on presidential performance. Instead, Erikson wrote,

A presidential penalty explanation fits the data nicely. By this explanation, the midterm electorate penalized the presidents party for being the party in power: Holding constant the presidential year House vote, the presidents party does much worse at midterm than it would if it did not control the presidency.

While substantial midterm losses for the incumbent presidents party are inevitable under most circumstances, that does not mean external developments have no influence on the scope of the outcome.

Kitschelt, quoting James Carville, noted in his email: Its the economy, stupid. And that means inflation, the supply chain troubles and the inability of the Democrats to extend the social safety net in an incremental fashion.

The inflation rate, Dritan Nesho, the director of civic technology and engagement at Microsoft and a co-director of the Harvard-Harris Poll, wrote in an email,

is now outpacing wage growth. As a consequence close to 4 in 10 voters are saying that their personal financial situation is getting worse. This figure is up from the low 20s in May and importantly, majorities of voters are not confident in either the Biden administration keeping inflation at bay (56 percent not confident/44 percent confident) and also of the Federal Reserve (53 percent not confident/47 percent confident).

In addition, Nesho said,

over two-third of voters (68 percent) believe illegal monthly border crossings have increased since Biden took office, 65 percent blame Bidens executive orders for encouraging illegal immigration, and 68 percent want stricter policies to reduce the flow of people across the border.

In January 2021, the month Biden took office, the University of Michigans consumer sentiment index stood at 79. By Nov. 1, the index had fallen to 66.8, the lowest it has been since November 2011. Richard Curtin, director of the consumer sentiment survey, wrote in a commentary accompanying the report: Consumer sentiment fell in early November to its lowest level in a decade due to an escalating inflation rate and the growing belief among consumers that no effective policies have yet been developed to reduce the damage from surging inflation.

Similarly, when Biden took office in January, the Bureau of Labor Statistics reported that the inflation rate was 1.4 percent; as of October this year, the rate had risen to 6.2 percent.

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House Democrats have a new strategy to engage voters of color in the midterm elections – NPR

Posted: at 1:32 pm

Democratic congressional candidate Rochelle Garza speaks with voters in Brownsville, Texas, in September. Many Latino voters in South Texas turned against Democrats during last year's presidential election and winning them back could prove critical to the party's hopes of retaining control of Congress during next year's midterms. Eric Gay/AP hide caption

Democratic congressional candidate Rochelle Garza speaks with voters in Brownsville, Texas, in September. Many Latino voters in South Texas turned against Democrats during last year's presidential election and winning them back could prove critical to the party's hopes of retaining control of Congress during next year's midterms.

The Democratic Congressional Campaign Committee is launching a new, multimillion-dollar effort to engage and mobilize voters of color ahead of the midterm elections, including investments in local organizing and a seven-figure research and polling effort.

The plan, the details of which were shared first with NPR, includes an initial $30 million investment to hire local community organizers, launch targeted advertising campaigns aimed at nonwhite communities, as well as building voter protection and education programs. The committee is also working to combat disinformation efforts that are specifically focused on voters of color.

The announcement comes as Democrats are preparing to defend their slim congressional majorities in 2022, and as many in the party are still assessing their unexpected losses in significant elections this month. It is an early signal of how national Democrats plan to work to ensure that the racially diverse coalition that elected President Biden and delivered victories in key states across the country that gave Democrats a bare Senate majority shows up again.

"What we have learned from studying the 2020 election is when we invest in communities of color, it pays real dividends," New York Rep. Sean Patrick Maloney, chair of the Democratic Congressional Campaign Committee, said in an interview.

The announcement is also an indication that party leaders are aware that the broad, racially diverse coalition of voters that elected Democrats must be engaged consistently, and must not be treated as monolithic groups. While Democrats won the White House last year, they lost ground among nonwhite voters without a college education. Biden's campaign faced criticism over mixed results among varied segments of the Latino electorate, missteps that were blamed for setbacks in critical states like Florida and Texas, where a number of key House races will be decided in 2022.

Democrats are also facing aggressive redistricting by Republicans in some states, as well as souring approval ratings for the president and the Democratic Party.

Georgia Rep. Nikema Williams, a freshman who is leading the committee's efforts around voting rights and voter education, said that "we can't just show up in a community and expect people to listen to us and turn out overnight."

Williams, who is also the chair of the Georgia Democratic Party, said that recent Democratic victories in her state were the result of years of aggressive and consistent work.

"And I had a novel idea, what if we did year-round organizing and continued to bring information to the voters and continued to let voters know how Democrats were delivering for them? That's what we did in Georgia, that's how we won in Georgia, and that's what we're doing with the DCCC," Williams said.

Maloney said that as part of the Building our Base Project, he wants "boots on the ground much earlier, not just showing up at election time, and putting the resources behind it with a culturally competent, diverse team that knows what it's doing."

The Democratic Congressional Campaign Committee itself was the subject of complaints over diversity in its leadership, prior to Maloney's tenure as chairman. The committee says its staff is currently comprised of nearly 50% people of color, and the senior leadership team is 71% people of color. The DCCC also elevated Tasha Cole, the deputy executive director for diversity, equity and inclusion, as a member of the senior leadership team and added Missayr Boker to lead the committee's independent expenditure. Boker is the first Black person and person of color to hold that role.

The committee also plans to target Republican efforts to spread misinformation, as well as to cast all Democratic candidates as far-left. The committee says it will have a particular focus on social media platforms frequently used in communities of color. Voters of color were flooded with disinformation in the days leading up to the November 2020 election, and some Democrats say the party didn't do enough to combat it.

"It's not enough to just wave it away and pretend it doesn't matter. We need to take these lies and distortions seriously," Maloney said. "We need to have a robust effort to counter that disinformation, and we need to do research so we understand exactly how to do that without turning off our most reliable voters."

The Democratic National Campaign Committee is also launching its own voter protection team and increasing its efforts to educate voters. Federal voting rights legislation remains stalled in the Senate, despite repeated attempts by Democrats to pass bills in response to a wave of state-level laws championed by Republicans that restrict ballot access. Democrats and voting rights advocates say those laws have a disproportionate impact on people of color.

"We're making sure that we are doubling down on making sure that people know how to navigate all of these new rules and new laws, and making sure that any roadblocks to the ballot box are 'un-hurdled' by the DCCC," Williams said. "We should not have to out-organize our way out of voter suppression, but we're not giving up."

House Republicans have been taking cues from Democrats in many ways when it comes to candidate recruitment in recent years as they focus on a more diverse slate of recruits. The National Republican Congressional Committee says this year that nearly 90% of its 70 target districts have a female, veteran or minority candidate already filed to run.

It's a strategy the GOP used in 2020 when it was able to significantly narrow Democrats' majority in the House, even as Republicans lost control of the Senate and White House.

Asked about Republican recruiting efforts, Maloney said the House Republican Caucus "is not a diverse group of people that represents the full mosaic of the United States."

"What I can tell you is that we will field a truly diverse group of candidates. And I should point out, that some of our candidates who are running in the toughest districts are people of color, and we know that they have done an extraordinary job of telling their story and bringing voters to their cause."

Maloney ticked off the names of a number of Democratic incumbents of color: Reps. Lucy McBath of Georgia, Antonio Delgado of New York, Jahana Hayes of Connecticut and Lauren Underwood of Illinois.

"They have all done an extraordinary job of winning tough districts that are not diverse. And so we believe, absolutely in our hearts, that our diverse candidates are our true strength, not just in districts that are diverse, but in some of the most competitive districts of the country," he added.

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How one election left this powerful Democratic organization fighting to survive – POLITICO

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News of a federal wiretap didnt hurt Norcross clout. Neither did Democratic Gov. Phil Murphy, an ally of public sector unions who hired lawyers to dig deeply into Norcross use of the state's tax incentives. Nor did progressive efforts to disrupt Norcross' power in the region's principal city of Camden or its suburbs.

Instead, the biggest hit to the power of Norcross came this month, when a truck driver who spent $10,000 on his campaign defeated Sweeney. It was one of the biggest political upsets in New Jersey history and the biggest in the nation this year a dark omen for Democrats worried about the 2022 midterms. That night, South Jersey Democrats also lost two of their six state Senate seats and four of their 12 state Assembly seats, accounting for most of the Democratic Partys losses in New Jersey, where Murphy stumbled to a narrow, 3-point reelection victory.

Now, Trenton insiders are looking slack-jawed at the diminishment of South Jersey Democrats dominance. Sweeney, Norcross and their machine fell victim to a blue collar revolt where the partys decades-long cultivation of conservative-leaning voters and adherence to flawed internal polling failed to predict or resist a Republican wave.

The arithmetic is undeniable in the fact that weve lost seats in the southern region, said state Assemblymember John Burzichelli (D-Gloucester), a 19-year incumbent in Sweeneys district who also lost his seat this month. I think that speaks for itself.

In this 2018 file photo, New Jersey Gov. Phil Murphy addresses a gathering in the Assembly chamber of the Statehouse in Trenton, New Jersey. | Mel Evans/AP Photo

The outcome says something important about Democratic chances in the suburbs ahead of next year, when the country will hold 36 governors races on top of congressional elections. The same red wave that handed Sweeney his loss and put Glenn Youngkin in the Virginia governor's mansion did less damage to Democrats in the more white-collar suburbs in the northern half of New Jersey. As the Democrats in South Jersey also sustained losses at the local level, losing several county offices in the region, Democrats in the north flipped one Senate seat and lost just one Assembly seat. Murphy appeared to do better in some of those areas, too.

That suggests the Republican resurgence of 2021 is not a reversal of the 2018 midterms, when Democrats made remarkable strides in suburbs across the country including in New Jersey. Affluent and middle-class suburbs and exurbs that turned from purple to blue three years ago may still be Democratic. Its in more blue-collar communities, places that already backed Donald Trump, where voters who had supported moderate Democrats for years decided to vote Republican this time around.

Here in Trenton, the impact is already being felt: While South Jersey Democrats still compromise a substantial voting bloc in the state Legislature, January will be the first time in 16 years that one of their own does not preside at the top of either the General Assembly or state Senate.

With Assembly Speaker Craig Coughlin set to stay in place and state Sen. Nicholas Scutari (D-Union) in line to replace Sweeney, its a political sea change. Sweeney had worked hand-in-hand with Christie to pare down pensions for new public workers and cut health benefits. Together, they took over struggling Atlantic City and overhauled its finances, restructured South Jerseys university system and designed a tax credit system that directed millions to Camden.

Prior the pandemic, Sweeneys relationship with Murphy was strained at the best of times, while the two engaged in open political warfare during the worst times something that almost led to a government shutdown as they fought over Murphys first budget. Scutaris rise to power owes more to the now-larger Democratic delegation in Middlesex County, in Central Jersey, whose priorities will be different than those of South Jersey Democrats.

Weve got to get away from those years when Mr. Norcross and Mr. Christie were an oversized influence, said state Sen. Richard Codey (D-Essex), whom Sweeney ousted as senate president 12 years ago.

How did it happen? In a somber concession announcement Wednesday, Sweeney blamed a red wave. Norcross, in an interview with POLITICO shortly after the election, blamed a national anti-Democratic mood defined by the partys progressive wing. Voters massively rejected that notion, which was largely defined from the top in Washington, then down through New Jersey, he said.

Steve Kush, a Republican consultant who has spent years running unsuccessful legislative candidates against the South Jersey Democratic machine and, in 2003, nearly came to blows with now-congressman Donald Norcross, Georges brother referred back to the man who beat Sweeney: Edward Durr.

Ed Durr said it best. Two words: Phil Murphy, said Kush, who helped Durrs longshot campaign. Kush said he believes that a general disenchantment with the South Jersey Democrats patronage machine may have also played a role. Theres a lot of folks with jobs in the county government who feel they have to be loyal to the machine. None of them will ever say it out loud. But they tell you. Im a Democrat because I have a job, he said.

The Murphy campaign, in a memo meant for public consumption, blamed the national environment for the close result in the governors race, in which Murphy beat Republican Jack Ciattarelli by about 75,000 votes. The memo credited a smart, aggressive turnout strategy of vote-by-mail and early voting that enabled it to deliver a victory in the face of historic New Jersey voting patterns, strong GOP turnout, and a challenging national environment for the Democratic Party. And progressives who detest the South Jersey Democratic machine celebrated Sweeney's defeat albeit to a conservative who had a history of anti-Muslim social media posts for which he's since apologized.

There is a dent in the machine. Theres an opening a small little hole and if you keep pushing it, the hole keeps getting bigger and bigger, said Ronsha Dickerson, a Camden activist and Norcross critic who said she left the Democratic Party because she lost faith in it but still votes that way.

In this Dec. 10, 2015, photo, Steve Sweeney speaks to a gathering at the Statehouse in Trenton, New Jersey. | Mel Evans/AP Photo

There have been signs of Democratic vulnerabilities in South Jersey for years. Trump, for instance, narrowly won Sweeneys district in 2016 and 2020.

Democrats pains in South Jersey werent felt as acutely further north, though a couple Democratic North Jersey counties Bergen and Passaic, for instance were far closer than expected, with Murphy winning them by a relatively narrow margin.

Ironically, though, it may have been a backlash against Murphy by rural and suburban blue collar South Jersey voters that helped doom Sweeney and the other South Jersey Democrats.

[Murphy] dragged the party so far left and I think the voter perception was [South Jersey Democrats] didnt do enough to stop him, said Chris Russell, a Ciattarelli campaign consultant. Ultimately, I think voters made a decision that, if theyre not going to stand up to him and get in his way, why have him? Theyre going to elect Republicans.

In 2017, Murphy won Gloucester County, Sweeneys home county, by about 13 points. In 2021, he lost it by 10. That result wasnt driven by Murphy getting less votes he got about 2,600 more than he did four years ago but by Ciattarelli getting 22,500 more votes than the last Republican gubernatorial candidate, Kim Guadagno.

Sweeney got only a few hundred less votes accross his district than he did in 2017, according to the latest tally. But Durr got over 11,000 more votes than Sweeneys Republican challenger, Fran Grenier, did four years ago. Thats despite the fact that the New Jersey Education Association, the states largest public sector union, spent over $5 million to boost Greniers candidacy as it feuded with Sweeney over pension contributions.

South Jersey Democrats built their dominance of the region by engaging with Republicans, independents and moderate Democrats, a less blue voting base than up north, without Democratic powerhouses like Essex and Hudson counties. But Democrats have also made inroads in central and northern New Jerseys suburbs. In once-solidly Republican Somerset County a more affluent suburban area of Central Jersey thats home to Ciattarelli as well as former Republican Gov. Christie Whitman Murphy did better than he did in 2017, and Democrats picked up a state Senate seat that had been held by a Republican for decades.

It doesnt bode well for the south, Somerset County Democratic Chair Peg Schaffer said. But we didnt anticipate this, that the Republican vote down there was very significant. Its very conservative down there and we have a progressive governor.

In North Jerseys wealthy Morris County, which used to be one of the biggest Republican vote plurality producers in the state, Ciattarelli netted 21,000 more votes than Murphy less than half of what Christie, a Morris County resident, netted over Democratic Gov. Jon Corzine in 2009.

Democrats cant count on Cumberland, Salem or Gloucester anymore, said Cook Political Report Editor Dave Wasserman, a New Jersey native, referring to the three counties in Sweeneys district. Their future is in Somerset and Morris Counties.

Were talking about a long-term realignment in voters support for the parties, he said.

But Republicans, having seen Norcross raise millions of dollars to spend against their candidates by hosting a couple fundraisers, arent celebrating their impending doom.

Knowing George Norcorss the way I know George Norcross, what it means is hes going to raise even more money and come at us even harder, Kush said. It means we better hunker down.

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Democrats plan an aggressive strategy on critical race theory claims – Business Insider

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They've called it a "racist dog whistle" and a "lie."

But those messages haven't helped Democrats tamp down the uproar Republicans are fueling over "critical race theory," now a misused catch-all term for teaching on race and diversity in K-12 schools that's firing up protests at school board meetings around the country.

In Virginia, Republican Gov.-elect Glenn Youngkin exploited the term and pledged to "ban" it in classrooms on his first day as governor, even though critical race theory an academic approach to examining racial bias is most often taught in law schools. Republicans plan to lean into the issue in the 2022 election cycle.

Democratic strategists say the party should hit back harder against "divisive" GOP claims while not losing sight of the priority for voters; the economy.

"On a political level it's a real threat that is allowing Republicans to claw back the inroads that Democrats have made in the suburbs over the last couple of election cycles," said Jim Manley, a longtime aide to former Senate Minority Leader Harry Reid.

Democrats haven't yet pushed back on this issue enough, but the "good news" is the party's response is effective and there's time to make the case before the 2022 elections, said Jesse Ferguson, a Democratic strategist. They just need to make the case "relentlessly," he said.

"Voters run from the Republicans when Democrats peel back the onion on what these claims really mean," he said. "It's not just that Republicans want a bigger role for parents in education, it's that Republicans are willing to let white supremacists write curricula."

The Democratic Congressional Campaign Committee, the House campaign arm for Democrats, downplayed the threat to the party in congressional races. This fall, they tested responses to false claims about critical race theory in K-12 schools. The messages they say resonate most with battleground voters: Democrats want to teach the truth about US history and honor those who fought to make the country better, Republicans are trying to divide Americans and Democrats want to deliver for American families.

Democrats' message to voters in 2022 will be more compelling than "Republicans' divisive lies," said Chris Taylor, a DCCC spokesman.

"House Democrats safely reopened schools, delivered tax relief in the Child Tax Credit, and we're fighting for universal pre-K and paid family leave," he said in a statement to Insider. "Republicans stand in opposition to American families. Our bet heading into 2022 is that voters will choose progress over division."

The message tracks with a new Washington Post-ABC News poll that found most Americans overall said public schools should teach "a good amount" or more about how the history of racism affects the US today. While most Democrats and independents said schools should teach about the effects of racism, just about 4 in 10 Republicans agreed.

But Manley said the results in Virginia's recent gubernatorial race show that Republicans used critical race theory as a wedge issue to raise broader concerns among suburban voters. To suggest it's just an issue for the GOP base is "kind of like putting your head in the sand," he said.

"We need to figure out how to address this phenomenon without overplaying our hand and or allowing Republicans to, you know, break the education system in this country," Manley said.

A Fox News Voter Analysis survey found 25 percent of Virginia voters polled cited the critical race theory debate as the most important factor in their support for a gubernatorial candidate, and most of those voters went for Youngkin over Democrat Terry McAuliffe.

DCCC chair, Rep. Sean Maloney of New York, told The Washington Post that Democrats have "learned from the lies and distortions of the last election." Democrats will argue that "children need to learn their history all of it without censorship or politics limiting what they can learn," Maloney told columnist Greg Sargent.

Democratic pollster Celinda Lake said Democrats are on "strong terrain" when they talk about "teaching the truth" about racism in history and they should be more aggressive in their responses.

"Voters are wildly, wildly in favor of it and even half of Republicans think some of this stuff should be taught," she said. "Their strategy is, mobilize their base and distract us, and shame on us if we get distracted."

That's not to say there aren't lessons to be learned from Virginia. Lake said the bigger problem for McAuliffe wasn't about critical race theory, but his "problematic" statement during a debate that parents shouldn't be "telling schools what they should teach." Now, House Republicans are calling for a "parents bill of rights" in education.

Democrats need a better answer about parental involvement, Lake added, and the "irony" is that more Democrats are parents than Republicans. "We ought to be very comfortable with this," she said.

The real issue for voters is whether a candidate is on the side of parents and students or not, Ferguson said. And Democrats have a strong case to make about providing money for schools and blocking "censorship," but they need to lean into it.

"When Democrats talk about how Republican plans would put politicians in charge of classrooms and censor teachers, the swing voters who Republican voters thought they were winning quickly flee," he said.

It's not enough to say that Republicans are lying about critical race theory being taught in classrooms when right-wing media is driving the issue and parents are also hearing about it from other parents at their schools, Ferguson said.

"It can't be dismissed as just a lie," he said. "It needs to be defeated as a way to put politicians in charge of the classroom and white supremacists in charge of the curriculum."

"Culture wars" will be a problem in 2022 races, and "Democrats are always on defense," said former Ohio state Sen. Nina Turner, a progressive leader. Democrats shouldn't run from the conversation about critical race theory, but they need to quickly pivot to real economic challenges people are facing in their everyday lives.

"If the Democrats would focus most of their time delivering on the promises that they made in 2020, then people couldn't get distracted with all this other nonsense that the Republicans are throwing out there," she said.

Lake said the critical issue for Democrats is the economy and not education.

"I don't minimize the amount that the Republicans are doing to try to energize their base with this issue," Lake said. "But this is not a threat to us. The economy is the much bigger threat than critical race theory."

Insider would like to know how your school district is handling the critical race theory controversy. Please contact Nicole Gaudiano at ngaudiano@insider.com.

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The Memo: Democrats may rue pursuit of Bannon | TheHill – The Hill

Posted: at 1:31 pm

Democrats and other critics of former President TrumpDonald TrumpBiden sends 2016 climate treaty to Senate for ratification US, China ease restrictions on journalists Americans keep spending MORE celebrated when criminal charges were leveled againstStephen Bannon late last week.

But the political downside of the pursuit of Bannon is becoming clearer by the day.

Theres no guarantee that the underlying purpose of the prosecution to compel Bannon to cooperate with the House committee investigating the Jan. 6 insurrection will work.

Bannon may ultimately prefer the risk of a fairly short jail sentence, and the martyrdom it would confer on him from Trump supporters, over testifying.

Even if he were to cooperate, the question then becomes whether the public will learn anything more damning than it already knows about Bannon and his former boss.

After all, Bannon said on his podcast the day before the riot that all hell is going to break loose tomorrow. And Trumps central role in inciting the insurrection was so blatant that he became the first president in American history to be impeached twice.

Above all, the criminal case has given Bannon the biggest platform he has enjoyed in years.

The news that he had been indicted on two counts of contempt of Congresson Friday was the lead story on the websites of The New York Times and other leading news organizations.

Bannons initial court appearance on Monday was another media circus, with network newscasts running footage of Trumps former chief White House strategist lambasting the prosecution and President BidenJoe BidenIdaho state House passes worker vaccine compensation bill Biden sends 2016 climate treaty to Senate for ratification Rubio vows to slow-walk Biden's China, Spain ambassador nominees MORE. Bannon live streamed his comments outside the court on the social network Gettr, a favorite among pro-Trump conservatives.

On Thursday, Bannon will get another bite of the publicity cherry if, as expected, he is formally arraigned.

Bannon revels in it. He loves it, said Allan Lichtman, a professor of history at American University, who compared the former Trump aides zeal for media attention to that of another associate of the former president, Roger StoneRoger Jason StoneThe Memo: Democrats may rue pursuit of Bannon DeSantis floats formation of police force to crack down on election crimes Stone says he'll run for Florida governor if DeSantis doesn't do audit MORE.

Bannons ardor for the spotlight is well known throughout Washington including among reporters who find him more personally engaging than his sinister public persona suggests.

He had seemed to be a marginalized figure after Trump disowned him back in early 2018 following the publication of a damaging book by the journalist Michael Wolff. But Bannon ultimately made his way back into Trumps good graces, conferring with him following the then-presidents election loss last year.

Now, in seeking to get details of what exactly was said between Trump and Bannon, the former aides adversaries have restored him to the center of the political stage. From there, he is sure to amplify Trump's fictions about election fraud, among other things.

But does all of that mean that Democrats and Merrick GarlandMerrick GarlandThe Memo: Democrats may rue pursuit of Bannon Unions sue in bid to represent Connecticut National Guard members Top Senate Democrat calls on attorney general to fire prisons chief MOREs Department of Justice (DOJ) are wrong tohave pressed the case against him?

Not necessarily.

The DOJ would presumably not pursue the case if it was not confident of conviction.Announcing the indictment, Garland said he was honoring a promise to "show the American people by word and deed that the department adheres to the rule of law."

Allowing Trump and Bannon together to thumb their noses at a congressional inquiry into the grave attack on the Capitol was simply unacceptable for most Democrats and many other Trump critics.

Reps. Bennie ThompsonBennie Gordon ThompsonThe Memo: Democrats may rue pursuit of Bannon Trump allies target Katko over infrastructure vote Meadows 'between a rock and a hard space' with Trump, Jan. 6 panel MORE (D-Miss.) and Liz CheneyElizabeth (Liz) Lynn CheneyThe Memo: Democrats may rue pursuit of Bannon House to vote Wednesday to censure Gosar, remove him from committees Gosar defends anime Ocasio-Cortez video to GOP MORE (R-Wyo.), the chairman and vice chairwoman of the Jan. 6 committee said in a statement that the indictment should send a clear signal to anyone who thinks they can ignore the Select Committee or try to stonewall our investigation: No one is above the law.

Some prominent Democrats were even more emphatic.

The indictment showed that even the insurrectionist allies of Donald Trump are not above the law and the American justice system is back in business, Rep. Jamie RaskinJamin (Jamie) Ben RaskinThe Memo: Democrats may rue pursuit of Bannon Subpoenas show Jan. 6 panel's focus on Trump's plans Overnight Energy & Environment Presented by American Clean Power Democrats prepare to grill oil execs MORE (D-Md.) tweeted.

Welcome back to the rule of law, Rep. Eric SwalwellEric Michael SwalwellThe Memo: Democrats may rue pursuit of Bannon Mo Brooks says he would 'be proud' if staff helped organize Jan. 6 rally GOP ekes out win in return of Congressional Baseball Game MORE (D-Calif.) tweeted as the news of Bannons indictment broke.

But, for Democrats, the problem is that the enemy Bannon and the GOP gets a votetoo.

In Bannons case, that means characteristically pugnacious rhetoric outside the courthouse about how he is taking down the Biden regime and how his criminal prosecution is going to be the misdemeanor from hell for Biden, Garland and others.

More substantively, the door is now open to future use of the same process by Republicans at whatever point they win back control of Congress an outcome that looks odds-on to happen a year from now.

Some Trump loyalists are already salivating at the prospect.

Joe Biden has eviscerated Executive Privilege, Rep. Jim JordanJames (Jim) Daniel JordanThe Memo: Democrats may rue pursuit of Bannon Meadows comes under growing Jan. 6 panel spotlight Sunday shows preview: Biden administration confronts inflation spike MORE (R-Ohio) tweeted on Friday.

Referring to key Biden aides, he added, There are a lot of Republicans eager to hear testimony from Ron KlainRon KlainThe Memo: Democrats may rue pursuit of Bannon Manchin uncertain Biden plan will address inflation Biden aides offer praise for Harris after critical CNN report MORE and Jake SullivanJake SullivanRubio vows to slow-walk Biden's China, Spain ambassador nominees The Memo: Democrats may rue pursuit of Bannon US, China get chance for cool-down with virtual summit MORE when we take back the House.

HouseRepublican Conference Chairwoman Elise StefanikElise Marie StefanikThe Memo: Democrats may rue pursuit of Bannon Virginia emerging as ground zero in battle for House majority Republicans look to education as winning issue after Virginia successes MORE (R-N.Y.) complained, also on Twitter, that during former President ObamaBarack Hussein ObamaBriahna Joy Gray: White House is setting Harris up to move past her The Memo: Democrats may rue pursuit of Bannon Biden's decision on Fed chair said to be 'imminent' MOREs time in office, both former Attorney General Eric HolderEric Himpton HolderThe Memo: Democrats may rue pursuit of Bannon Ben Affleck, Tracee Ellis Ross join anti-gerrymandering fundraiser with Clinton, Holder North Carolina legislature approves new US House map MORE and former IRS official Lois Lerner were held in contempt of Congress and no indictments or arrests were made.

Even some Republicans critical of Trump question whether the precedents currently being set will have bad consequences further down the line.

This is dangerous ground, said Rick Tyler, a GOP strategist who has been strongly critical of Trump for years. Its tit-for-tat. When you have power, you dont use it to govern, you use it to exact revenge from your political enemies.

Others,including Lichtman, counter by saying that Democrats need to show some determination in their pursuit of figuressuch as Bannon.

One of the failings of the Democrats is that they dont have much of a backbone, he said. Republicans are ruthless, they will do whatever it takes.

Democrats are trying to take a page from that playbook now.

But the risks are higher than they might have imagined.

The Memo is a reported column by Niall Stanage.

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